New in this release
Example lists of prioritized targets for:
M. tuberculosis
P. falciparum
T. brucei
T. cruzi
L. major
B. malayi (Kumar et al.)
Disclaimer: these prioritized lists have been created and made public by users of the site and reflect the criteria and interests of the respective authors. They may contain complete prioritized genomes or just subsets of genes (i.e. only kinases).
There are more updates in this release of TDR Targets. Check the release notes for a detailed description of all changes.
News
TDR Targets v3 release.
Posted: 24.Mar.2009
This is our third release, which brings increased data coverage for all genomes. Check the release notes for a detailed description of changes in this release.
TDR Targets publication.
Posted: 24.Mar.2009
A paper describing the TDR Targets database has been published in the November, 2008 issue of Nature Reviews Drug Discovery.
New TDR Targets release.
Posted: 30.Jun.2008
This is our second release (since we started versioning the database, that is). Check the release notes for a detailed description of changes in this release.
New genomes in TDR Targets.
Posted: 7.Mar.2008
The genomes of Brugia malayi and its Wolbachia endosymbiont, Mycobacterium leprae, Toxoplasma gondii and Plasmodium vivax are now included in TDR Targets. For a summary of available data for these genomes, check the summary table at the bottom of this page.
Read old news posts here.
Welcome
This site is part of a WHO/TDR project seeking to exploit the availability of diverse datasets to facilitate the identification and prioritization of drug targets in pathogens causing neglected diseases.
The TDR Targets database functions both as a website where researchers can look for information on their targets of interest; and as a tool for prioritization of targets in whole genomes. Using the database as a tool, researchers can quickly prioritize a genome of interest by performing any number of individual queries on a species of interest, then assigning numerical weights to each query (in the history page) to finally obtain a ranked list of genes by combining the weighted queries.
Getting started
- If you are a first time user and you want to leverage the full benefits of the database, you may want to quickly browse our slideshow tutorials.
- To search for targets, click on search.
- To examine and work with queries that you have previously run (for example to give scores to each query and then combine them to obtain a prioritized list of targets), click on history.
- To examine queries that others have made publicly available, click on posted lists of targets.
- To examine the entries in the targets Survey, click on drug targets survey.
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