Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0653 | 0.0802 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0653 | 0.0802 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0653 | 0.1189 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.003 | 0.0484 | 0.0874 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0093 | 0.1977 | 0.366 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.006 | 0.1186 | 0.1186 |
Echinococcus multilocularis | RUN | 0.006 | 0.1186 | 0.1186 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.0552 | 0.0552 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0239 | 0.5374 | 0.5374 |
Schistosoma mansoni | intermediate filament proteins | 0.0055 | 0.1082 | 0.1082 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.025 | 0.1007 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1186 | 0.2183 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.3021 | 0.5609 |
Brugia malayi | hypothetical protein | 0.012 | 0.2594 | 0.4811 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.1977 | 0.1977 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0653 | 0.0592 |
Schistosoma mansoni | hypothetical protein | 0.006 | 0.1186 | 0.1186 |
Brugia malayi | hypothetical protein | 0.0239 | 0.5374 | 1 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0027 | 0.0416 | 0.0416 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0653 | 0.0592 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.025 | 0.1007 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0016 | 0.0016 |
Onchocerca volvulus | 0.0037 | 0.0653 | 0.112 | |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0312 | 0.707 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.1977 | 0.1977 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0055 | 0.1082 | 0.1989 |
Brugia malayi | hypothetical protein | 0.006 | 0.1186 | 0.2183 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0055 | 0.1082 | 0.1989 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0653 | 0.0802 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.1288 | 0.1288 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.2594 | 0.4811 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.025 | 0.1007 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0653 | 0.3197 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0202 | 0.4515 | 0.8396 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0027 | 0.0416 | 0.0416 |
Onchocerca volvulus | 0.0055 | 0.1082 | 0.1873 | |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0511 | 0.0924 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0553 | 0.0553 |
Trichomonas vaginalis | set domain proteins, putative | 0.0253 | 0.5707 | 0.8001 |
Loa Loa (eye worm) | intermediate filament protein | 0.0055 | 0.1082 | 0.1989 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0653 | 0.0802 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0653 | 0.1189 |
Onchocerca volvulus | 0.0037 | 0.0653 | 0.112 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0653 | 0.3882 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0553 | 0.1002 |
Brugia malayi | hypothetical protein | 0.006 | 0.1186 | 0.2183 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0653 | 0.1302 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0202 | 0.4515 | 0.8396 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.1288 | 0.1288 |
Schistosoma mansoni | rab6-interacting | 0.006 | 0.1186 | 0.1186 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0553 | 0.0553 |
Schistosoma mansoni | rab6-interacting | 0.006 | 0.1186 | 0.1186 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0653 | 0.1189 |
Echinococcus granulosus | dna polymerase eta | 0.002 | 0.025 | 0.025 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0093 | 0.1977 | 0.366 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0074 | 0.1512 | 0.1512 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0653 | 0.1302 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0074 | 0.1512 | 0.1512 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0356 | 0.8117 | 0.8117 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1182 | 0.3008 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0653 | 0.0802 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0074 | 0.1512 | 1 |
Brugia malayi | N-terminal motif family protein | 0.0193 | 0.4299 | 0.7993 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0054 | 0.1051 | 0.7867 |
Schistosoma mansoni | lamin | 0.0055 | 0.1082 | 0.1082 |
Brugia malayi | MH2 domain containing protein | 0.0128 | 0.2773 | 0.5146 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.025 | 0.1007 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.006 | 0.1186 | 0.1186 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0033 | 0.0553 | 0.0553 |
Onchocerca volvulus | 0.0055 | 0.1082 | 0.1873 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0653 | 0.1189 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.1288 | 0.1288 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.0552 | 0.0552 |
Brugia malayi | Doublecortin family protein | 0.006 | 0.1186 | 0.2183 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.025 | 0.025 |
Schistosoma mansoni | regulator of G protein signaling | 0.0009 | 0.0016 | 0.0016 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.1977 | 0.1977 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.025 | 0.1007 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0193 | 0.4299 | 0.7526 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0016 | 0.0016 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0016 | 0.0016 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.1977 | 0.1977 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0933 | 0.0933 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0054 | 0.1051 | 0.8876 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.025 | 0.1007 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.051 | 0.051 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.1182 | 0.1182 |
Schistosoma mansoni | polycystin 1-related | 0.006 | 0.1186 | 0.1186 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0054 | 0.1051 | 0.6346 |
Loa Loa (eye worm) | hypothetical protein | 0.0202 | 0.4515 | 0.8396 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.1977 | 0.1977 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.1977 | 0.1977 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0653 | 0.1302 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0312 | 0.707 | 1 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0074 | 0.1512 | 0.1851 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0653 | 0.0802 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0074 | 0.1512 | 0.1512 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0653 | 0.1189 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0416 | 0.0746 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.005 | 0.0962 | 0.0962 |
Loa Loa (eye worm) | hypothetical protein | 0.0239 | 0.5374 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0054 | 0.1051 | 0.6714 |
Echinococcus granulosus | GPCR family 2 | 0.0064 | 0.1288 | 0.1288 |
Schistosoma mansoni | lamin | 0.0055 | 0.1082 | 0.1082 |
Onchocerca volvulus | 0.0031 | 0.0511 | 0.087 | |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0962 | 0.1764 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.003 | 0.0484 | 0.0874 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.025 | 0.025 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.2594 | 0.453 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0653 | 0.0802 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0653 | 0.1302 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0011 | 0.0041 | 0.0046 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0064 | 0.1288 | 0.1288 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.025 | 0.0436 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0653 | 0.0592 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.1182 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.1186 | 0.2183 |
Echinococcus granulosus | tumor protein p63 | 0.0342 | 0.7767 | 0.7767 |
Echinococcus granulosus | geminin | 0.0341 | 0.7753 | 0.7753 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0511 | 0.0511 |
Onchocerca volvulus | 0.0049 | 0.0933 | 0.161 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0653 | 0.1189 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.025 | 0.0436 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0024 | 0.0358 | 0.0358 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0074 | 0.1512 | 0.1851 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0074 | 0.1512 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0033 | 0.0553 | 0.0553 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.025 | 0.1007 |
Onchocerca volvulus | 0.0253 | 0.5707 | 1 | |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0044 | 0.0044 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0074 | 0.1512 | 1 |
Schistosoma mansoni | loxhd1 | 0.006 | 0.1186 | 0.1186 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.025 | 0.1007 |
Echinococcus granulosus | lamin | 0.0055 | 0.1082 | 0.1082 |
Brugia malayi | hypothetical protein | 0.0054 | 0.1051 | 0.1931 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.025 | 0.0436 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0653 | 0.5466 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1182 | 0.1182 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.1182 | 0.1182 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0016 | 0.0016 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0653 | 0.0653 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0653 | 0.1189 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0653 | 0.1189 |
Brugia malayi | Pre-SET motif family protein | 0.0033 | 0.0553 | 0.1002 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0653 | 0.0653 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0606 | 0.11 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0016 | 0.0016 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0074 | 0.1512 | 0.1512 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.1288 | 0.1288 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.006 | 0.1186 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0653 | 0.0802 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0653 | 0.1189 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0128 | 0.2773 | 0.5146 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0033 | 0.0553 | 0.4607 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.118 | 0.9978 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0653 | 0.0802 |
Schistosoma mansoni | lipoxygenase | 0.0356 | 0.8117 | 0.8117 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0074 | 0.1512 | 1 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0653 | 0.1189 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1512 | 0.2792 |
Onchocerca volvulus | 0.006 | 0.1186 | 0.2055 | |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0011 | 0.0044 | 0.0044 |
Schistosoma mansoni | hypothetical protein | 0.0138 | 0.3021 | 0.3021 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0202 | 0.4515 | 0.8396 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.1182 | 0.1852 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.025 | 0.025 |
Echinococcus multilocularis | lamin | 0.0055 | 0.1082 | 0.1082 |
Onchocerca volvulus | 0.005 | 0.0962 | 0.1661 | |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0653 | 0.0653 |
Brugia malayi | Pre-SET motif family protein | 0.0223 | 0.4991 | 0.9285 |
Brugia malayi | intermediate filament protein | 0.0055 | 0.1082 | 0.1989 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0933 | 0.0933 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1182 | 0.3008 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0009 | 0.0016 | 0.0016 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0033 | 0.0553 | 0.0553 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1051 | 0.1931 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0653 | 0.0653 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.4299 | 0.7993 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1182 | 0.3008 |
Schistosoma mansoni | hypothetical protein | 0.0341 | 0.7753 | 0.7753 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.1977 | 0.1977 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0016 | 0.0016 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0653 | 0.1189 |
Echinococcus granulosus | intermediate filament protein | 0.0055 | 0.1082 | 0.1082 |
Echinococcus granulosus | lamin dm0 | 0.0055 | 0.1082 | 0.1082 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0009 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | doublecortin family protein | 0.006 | 0.1186 | 0.2183 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0653 | 0.1189 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.025 | 0.025 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.1288 | 0.1288 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.025 | 0.025 |
Echinococcus multilocularis | lamin dm0 | 0.0055 | 0.1082 | 0.1082 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0009 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0128 | 0.2773 | 0.5146 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0552 | 0.0552 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0312 | 0.707 | 1 |
Schistosoma mansoni | dep domain containing protein | 0.0009 | 0.0016 | 0.0016 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.025 | 0.1007 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.707 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0653 | 0.3197 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.025 | 0.1007 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0064 | 0.1288 | 0.2374 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.025 | 0.1007 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1059 | 0.1945 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.006 | 0.1186 | 0.1186 |
Onchocerca volvulus | 0.006 | 0.1186 | 0.2055 | |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.1288 | 0.2374 |
Echinococcus granulosus | RUN | 0.006 | 0.1186 | 0.1186 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0064 | 0.1288 | 0.1288 |
Echinococcus multilocularis | tumor protein p63 | 0.0342 | 0.7767 | 0.7767 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0152 | 0.3349 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.1182 | 0.7385 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.2594 | 0.4811 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0511 | 0.0924 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.707 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1182 | 0.1182 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0074 | 0.1512 | 0.1512 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0016 | 0.0016 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0312 | 0.707 | 0.5 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.707 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0356 | 0.8117 | 0.8117 |
Echinococcus multilocularis | GPCR, family 2 | 0.0064 | 0.1288 | 0.1288 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0239 | 0.5374 | 0.5374 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.707 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0064 | 0.1288 | 0.2374 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.025 | 0.1007 |
Plasmodium falciparum | LCCL domain-containing protein | 0.006 | 0.1186 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0235 | 0.5282 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0064 | 0.1288 | 0.1288 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0074 | 0.1512 | 0.1512 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0358 | 0.0358 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.2594 | 0.453 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0074 | 0.1512 | 0.1512 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0009 | 0.0016 | 0.0016 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0653 | 0.0592 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0152 | 0.3349 | 0.6158 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0024 | 0.0358 | 0.0358 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0138 | 0.3021 | 0.5609 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0933 | 0.171 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0653 | 0.1302 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0074 | 0.1512 | 0.1851 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.707 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.025 | 0.0436 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0033 | 0.0553 | 0.0553 |
Onchocerca volvulus | 0.0033 | 0.0553 | 0.0944 | |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0033 | 0.0553 | 0.0553 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.006 | 0.1186 | 0.1186 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0074 | 0.1512 | 0.1851 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0392 | 0.0702 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1082 | 0.1989 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0653 | 0.0592 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.707 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0341 | 0.7753 | 0.7753 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.025 | 0.025 |
Echinococcus multilocularis | geminin | 0.0341 | 0.7753 | 0.7753 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0653 | 0.0592 |
Onchocerca volvulus | 0.0037 | 0.0653 | 0.112 | |
Brugia malayi | Latrophilin receptor protein 2 | 0.0064 | 0.1288 | 0.2374 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.025 | 0.1007 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0074 | 0.1512 | 0.2792 |
Trypanosoma brucei | unspecified product | 0.002 | 0.025 | 0.1007 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0074 | 0.1512 | 0.1851 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.006 | 0.1186 | 0.1186 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0653 | 0.0802 |
Echinococcus multilocularis | dna polymerase eta | 0.002 | 0.025 | 0.025 |
Leishmania major | hypothetical protein, conserved | 0.0054 | 0.1051 | 0.6346 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.707 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0392 | 0.0702 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.025 | 0.025 |
Loa Loa (eye worm) | histone methyltransferase | 0.0011 | 0.0044 | 0.0051 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0152 | 0.3349 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.707 | 1 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0074 | 0.1512 | 0.1512 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.0552 | 0.0552 |
Schistosoma mansoni | lipoxygenase | 0.0249 | 0.5613 | 0.5613 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0653 | 0.3197 |
Echinococcus multilocularis | musashi | 0.0055 | 0.1082 | 0.1082 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0223 | 0.4991 | 0.9285 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0653 | 0.1583 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0066 | 0.1342 | 0.1342 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0054 | 0.1051 | 0.6346 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.006 | 0.1186 | 0.1186 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.025 | 0.1007 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 0 % | Antagonist activity at human recombinant GluR6 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx at 10 uM by luminescence reporter assay relative to control | ChEMBL. | 19819046 |
Inhibition (functional) | = 17 % | Antagonist activity at human recombinant GluR5 expressed in HEK cells coexpressing aequorine assessed as inhibition of glutamate-induced Ca2+ influx at 10 uM by luminescence reporter assay relative to control | ChEMBL. | 19819046 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.