Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0323 | 0.0239 |
Onchocerca volvulus | 0.0031 | 0.0162 | 0.2138 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.0162 | 0.0229 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0038 | 0.0242 | 0.0535 |
Brugia malayi | jmjC domain containing protein | 0.0033 | 0.0188 | 0.0319 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0031 | 0.0162 | 0.0068 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0404 | 0.0325 |
Brugia malayi | MH2 domain containing protein | 0.024 | 0.2852 | 0.9831 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0188 | 0.0341 |
Brugia malayi | hypothetical protein | 0.0244 | 0.2899 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0162 | 0.0251 |
Schistosoma mansoni | bromodomain containing protein | 0.0135 | 0.1493 | 0.1481 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 0.364 | 1 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0098 | 0.0014 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0031 | 0.0162 | 0.0229 |
Echinococcus multilocularis | RUN | 0.004 | 0.0271 | 0.0188 |
Brugia malayi | ecdysteroid receptor | 0.0031 | 0.0162 | 0.0229 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0048 | 0.0376 | 0.0295 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0507 | 0.6295 | 0.6264 |
Schistosoma mansoni | jumonji domain containing protein | 0.0033 | 0.0188 | 0.0095 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.0162 | 0.0083 |
Schistosoma mansoni | heat shock protein | 0.0032 | 0.0168 | 0.0074 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.004 | 0.0271 | 0.0198 |
Echinococcus granulosus | FTZ F1 alpha | 0.0031 | 0.0162 | 0.0083 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0044 | 0.0323 | 0.0824 |
Echinococcus granulosus | geminin | 0.0527 | 0.6545 | 0.6851 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0031 | 0.0162 | 0.0251 |
Echinococcus granulosus | neuropeptide s receptor | 0.0507 | 0.6295 | 0.6587 |
Schistosoma mansoni | endoplasmin | 0.0032 | 0.0168 | 0.0074 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0162 | 0.0079 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.0162 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0387 | 0.1052 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0037 | 0.024 | 0.0165 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 0.364 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0033 | 0.0188 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0162 | 0.0251 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0387 | 0.1032 |
Trichomonas vaginalis | heat shock protein, putative | 0.0032 | 0.0168 | 0.0437 |
Brugia malayi | jmjC domain containing protein | 0.0129 | 0.1423 | 0.4729 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0188 | 0.0095 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.0162 | 0.0079 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.0162 | 0.0229 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0031 | 0.0162 | 0.0068 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0301 | 0.364 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0032 | 0.0168 | 0.896 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0404 | 0.0339 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0031 | 0.0162 | 0.0229 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0129 | 0.1423 | 0.1407 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.024 | 0.2852 | 0.9831 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0036 | 0.0225 | 0.0149 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0125 | 0.137 | 0.1297 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0031 | 0.0162 | 0.0229 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0404 | 0.0322 |
Echinococcus granulosus | zinc finger protein | 0.0042 | 0.0294 | 0.0223 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0507 | 0.6295 | 0.6264 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.004 | 0.0271 | 0.0198 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.024 | 0.2852 | 0.9831 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0757 | 0.9513 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0271 | 0.0637 |
Schistosoma mansoni | nuclear hormone receptor | 0.0031 | 0.0162 | 0.0068 |
Echinococcus granulosus | phd:f box containing protein | 0.0033 | 0.0188 | 0.0109 |
Onchocerca volvulus | 0.005 | 0.0398 | 1 | |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 0.364 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0301 | 0.364 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 0.364 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0031 | 0.0162 | 0.0068 |
Echinococcus multilocularis | geminin | 0.0527 | 0.6545 | 0.6515 |
Schistosoma mansoni | lipoxygenase | 0.0105 | 0.1112 | 0.1076 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0036 | 0.0225 | 0.0135 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0129 | 0.1423 | 0.1407 |
Onchocerca volvulus | 0.004 | 0.0271 | 0.5752 | |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.004 | 0.0271 | 0.0188 |
Echinococcus granulosus | RUN | 0.004 | 0.0271 | 0.0198 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0036 | 0.0225 | 0.0142 |
Schistosoma mansoni | polycystin 1-related | 0.004 | 0.0271 | 0.0183 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0098 | 0.0014 |
Schistosoma mansoni | zinc finger protein | 0.0033 | 0.0177 | 0.0084 |
Echinococcus multilocularis | zinc finger protein | 0.0042 | 0.0294 | 0.0212 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0031 | 0.0162 | 0.0229 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0031 | 0.0162 | 0.0251 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0098 | 0.0022 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 0.364 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0031 | 0.0162 | 0.0229 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 0.364 | 1 |
Loa Loa (eye worm) | doublecortin family protein | 0.004 | 0.0271 | 0.0637 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.0162 | 0.0068 |
Brugia malayi | jmjC domain containing protein | 0.0125 | 0.137 | 0.4542 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0025 | 0.0085 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0033 | 0.0188 | 0.0341 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0162 | 0.0251 |
Schistosoma mansoni | heat shock protein | 0.0032 | 0.0168 | 0.0074 |
Schistosoma mansoni | rab6-interacting | 0.004 | 0.0271 | 0.0183 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0033 | 0.0188 | 0.0095 |
Trichomonas vaginalis | heat shock protein, putative | 0.0025 | 0.0085 | 0.0207 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0033 | 0.0188 | 0.0341 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0031 | 0.0162 | 0.0251 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0507 | 0.6295 | 0.6587 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0033 | 0.0188 | 0.0109 |
Schistosoma mansoni | endoplasmin | 0.0032 | 0.0168 | 0.0074 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0025 | 0.0085 | 0.4506 |
Brugia malayi | Bromodomain containing protein | 0.0081 | 0.0808 | 0.2534 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0031 | 0.0162 | 0.0079 |
Trichomonas vaginalis | heat shock protein, putative | 0.0025 | 0.0085 | 0.0207 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0147 | 0.1654 | 1 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0033 | 0.0188 | 0.0095 |
Brugia malayi | heat shock protein 90 | 0.0032 | 0.0168 | 0.025 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0033 | 0.0188 | 0.0109 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0033 | 0.0188 | 0.6819 |
Schistosoma mansoni | lipoxygenase | 0.0177 | 0.2035 | 0.2057 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0031 | 0.0162 | 0.0251 |
Schistosoma mansoni | phd/f-box containing protein | 0.0033 | 0.0188 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0188 | 0.0342 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.1697 | 0.5718 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0033 | 0.0188 | 0.0341 |
Brugia malayi | Doublecortin family protein | 0.004 | 0.0271 | 0.0616 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0098 | 0.0014 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0129 | 0.1423 | 0.4741 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0048 | 0.0376 | 0.0309 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0387 | 0.1032 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0032 | 0.0168 | 0.0271 |
Brugia malayi | Endoplasmin precursor | 0.0032 | 0.0168 | 0.025 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0757 | 0.9513 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.0032 | 0.0168 | 0.0089 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0033 | 0.0188 | 0.0104 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0031 | 0.0162 | 0.0079 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0127 | 0.1395 | 0.1321 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0404 | 0.0339 |
Schistosoma mansoni | zinc finger protein | 0.0042 | 0.0294 | 0.0208 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0025 | 0.0085 | 0.4506 |
Plasmodium falciparum | LCCL domain-containing protein | 0.004 | 0.0271 | 1 |
Echinococcus multilocularis | heat shock protein 90 | 0.0032 | 0.0168 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0162 | 0.0251 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0031 | 0.0162 | 0.0079 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0031 | 0.0162 | 0.0068 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0031 | 0.0162 | 0.0251 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0031 | 0.0162 | 0.0251 |
Echinococcus granulosus | lamin | 0.0026 | 0.0098 | 0.0015 |
Trypanosoma cruzi | ISWI complex protein | 0.0033 | 0.0177 | 0.9438 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0033 | 0.0188 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.0162 | 0.0079 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0162 | 0.0083 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0301 | 0.364 | 1 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0033 | 0.0188 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0162 | 0.0251 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0188 | 0.0341 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0036 | 0.0225 | 0.0135 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.0398 | 0.0319 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0404 | 0.1113 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0031 | 0.0162 | 0.0229 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0031 | 0.0162 | 0.0229 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0031 | 0.0162 | 0.0251 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0031 | 0.0162 | 0.0079 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0404 | 0.1093 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0177 | 0.0084 |
Schistosoma mansoni | hypothetical protein | 0.0527 | 0.6545 | 0.6847 |
Schistosoma mansoni | hypothetical protein | 0.0527 | 0.6545 | 0.6847 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0031 | 0.0162 | 0.0083 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0031 | 0.0162 | 0.0083 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0271 | 0.0183 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0098 | 0.0015 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0037 | 0.024 | 0.0157 |
Trypanosoma brucei | ISWI complex protein | 0.0033 | 0.0177 | 0.4595 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0031 | 0.0162 | 0.0079 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0031 | 0.0162 | 0.0083 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0031 | 0.0162 | 0.0068 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0032 | 0.0168 | 0.896 |
Schistosoma mansoni | jumonji domain containing protein | 0.0125 | 0.137 | 0.1351 |
Brugia malayi | jmjC domain containing protein | 0.0033 | 0.0188 | 0.0319 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.004 | 0.0271 | 0.0188 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0033 | 0.0188 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0033 | 0.0188 | 0.0319 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0031 | 0.0162 | 0.0068 |
Brugia malayi | jmjC domain containing protein | 0.0033 | 0.0188 | 0.0319 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0031 | 0.0162 | 0.0229 |
Loa Loa (eye worm) | endoplasmin | 0.0032 | 0.0168 | 0.0271 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.2899 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0048 | 0.0376 | 0.0294 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 0.364 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0076 | 0.0743 | 0.0664 |
Plasmodium falciparum | heat shock protein 90 | 0.0032 | 0.0168 | 0.6071 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0404 | 0.0322 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0033 | 0.0188 | 0.0104 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0398 | 0.0319 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0177 | 0.2035 | 0.2069 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0031 | 0.0162 | 0.0083 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0031 | 0.0162 | 0.0251 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0033 | 0.0188 | 1 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0036 | 0.0225 | 0.0142 |
Echinococcus multilocularis | phd:f box containing protein | 0.0033 | 0.0188 | 0.0104 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0147 | 0.1654 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0025 | 0.0085 | 0.0207 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0098 | 0.0022 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0031 | 0.0162 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.081 | 0.2557 |
Echinococcus granulosus | heat shock protein | 0.0032 | 0.0168 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0927 | 0.2975 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0098 | 0.0015 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0225 | 0.0475 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0031 | 0.0162 | 0.0229 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0031 | 0.0162 | 0.0068 |
Schistosoma mansoni | loxhd1 | 0.004 | 0.0271 | 0.0183 |
Leishmania major | hypothetical protein, conserved | 0.0033 | 0.0188 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0031 | 0.0162 | 0.0068 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.004 | 0.0271 | 0.0188 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0387 | 0.1052 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0033 | 0.0188 | 0.0109 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0032 | 0.0168 | 0.896 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0757 | 0.9513 | 0.9509 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0127 | 0.1395 | 0.1389 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0031 | 0.0162 | 0.0083 |
Trypanosoma cruzi | ISWI complex protein | 0.0033 | 0.0177 | 0.9438 |
Plasmodium vivax | JmjC domain containing protein | 0.0033 | 0.0188 | 0.1902 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0147 | 0.1654 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.0398 | 0.1072 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0404 | 0.0325 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0031 | 0.0162 | 0.2138 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0162 | 0.0251 |
Brugia malayi | hypothetical protein | 0.004 | 0.0271 | 0.0616 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0875 | 0.2788 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0036 | 0.0225 | 0.0149 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.004 | 0.0271 | 0.0198 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0177 | 0.2035 | 0.1967 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0162 | 0.0251 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0036 | 0.0225 | 0.0135 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0031 | 0.0162 | 0.0068 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0032 | 0.0168 | 0.896 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0031 | 0.0162 | 0.0079 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0032 | 0.0168 | 0.896 |
Echinococcus multilocularis | heat shock protein | 0.0032 | 0.0168 | 0.0084 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0031 | 0.0162 | 0.0068 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0188 | 0.0321 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0301 | 0.364 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0031 | 0.0162 | 0.0229 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0125 | 0.137 | 0.1297 |
Schistosoma mansoni | coup transcription factor | 0.0031 | 0.0162 | 0.0068 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0033 | 0.0188 | 1 |
Brugia malayi | steroid hormone receptor | 0.0031 | 0.0162 | 0.0229 |
Brugia malayi | Bromodomain containing protein | 0.016 | 0.1814 | 0.6127 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0301 | 0.364 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0031 | 0.0162 | 0.0229 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0031 | 0.0162 | 0.2138 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.004 | 0.0271 | 1 |
Schistosoma mansoni | protein phosphatase 2C | 0.0033 | 0.0188 | 0.0095 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0032 | 0.0168 | 0.0235 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0036 | 0.0225 | 0.0135 |
Leishmania major | hypothetical protein, conserved | 0.0033 | 0.0177 | 0.8976 |
Brugia malayi | PHD-finger family protein | 0.0053 | 0.0441 | 0.1223 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0076 | 0.0743 | 0.0698 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0125 | 0.137 | 0.1364 |
Brugia malayi | nuclear hormone receptor | 0.0031 | 0.0162 | 0.0229 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0031 | 0.0162 | 0.2138 |
Schistosoma mansoni | rab6-interacting | 0.004 | 0.0271 | 0.0183 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0244 | 0.2899 | 0.2985 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0129 | 0.1423 | 0.1419 |
Onchocerca volvulus | 0.004 | 0.0271 | 0.5752 | |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0031 | 0.0162 | 0.0229 |
Brugia malayi | nuclear receptor NHR-88 | 0.0031 | 0.0162 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0188 | 0.0341 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0244 | 0.2899 | 0.2838 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0031 | 0.0162 | 0.0229 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0271 | 0.0637 |
Brugia malayi | hypothetical protein | 0.004 | 0.0271 | 0.0616 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0404 | 0.0325 |
Leishmania major | heat shock protein 83-1 | 0.0032 | 0.0168 | 0.8106 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0098 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0162 | 0.0251 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 0.94 % | Analgesic activity in mouse assessed as protection against acetic acid-induced writhing at one-tenth of LD50 administered subcutaneously 30 mins before acetic acid challenge measured after 1 hr relative to control | ChEMBL. | 19527932 |
Activity (functional) | = 1.18 % | Analgesic activity in mouse assessed as protection against acetic acid-induced writhing at one-tenth of LD50 administered subcutaneously 30 mins before acetic acid challenge measured after 4 hrs relative to control | ChEMBL. | 19527932 |
Activity (functional) | = 2.84 % | Analgesic activity in mouse assessed as protection against acetic acid-induced writhing at one-tenth of LD50 administered subcutaneously 30 mins before acetic acid challenge measured after 2 hrs relative to control | ChEMBL. | 19527932 |
Activity (functional) | = 9.47 % | Analgesic activity in mouse assessed as protection against acetic acid-induced writhing at one-tenth of LD50 administered subcutaneously 30 mins before acetic acid challenge measured after 3 hrs relative to control | ChEMBL. | 19527932 |
LD50 (ADMET) | = 330 mg Kg-1 | Toxicity in sc dosed albino mouse up to 24 hrs | ChEMBL. | 19527932 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.