Detailed information for compound 1069015

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 333.329 | Formula: C18H17F2NO3
  • H donors: 1 H acceptors: 1 LogP: 2.17 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@]12CO[C@H](N2[C@H](OC1)c1ccc(cc1)F)c1ccc(cc1)F
  • InChi: 1S/C18H17F2NO3/c19-14-5-1-12(2-6-14)16-21-17(13-3-7-15(20)8-4-13)24-11-18(21,9-22)10-23-16/h1-8,16-17,22H,9-11H2/t16-,17+,18-
  • InChiKey: AEZQGSQEXPUADE-BCDXTJNWSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0342 0.2169 0.4963
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.0033 0.0058 0.0058
Brugia malayi Pip kinase protein 1 0.0055 0.0212 0.0277
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0046 0.013
Onchocerca volvulus 0.0123 0.0679 0.1308
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0043 0.0127 0.0167
Schistosoma mansoni terminal deoxycytidyl transferase 0.0244 0.1501 0.1501
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0075 0.0348 0.0493
Brugia malayi hypothetical protein 0.0041 0.0113 0.0147
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0058 0.0233 0.0307
Echinococcus multilocularis geminin 0.0195 0.1165 0.1649
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0467 0.1308
Echinococcus multilocularis cpg binding protein 0.0103 0.0535 0.0758
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0025 0.0033
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0113 0.0113
Giardia lamblia DNA repair protein RAD52 0.0336 0.2134 0.5974
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0115 0.0115
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0233 0.0652
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0051 0.0186 0.052
Loa Loa (eye worm) DOMON domain-containing protein 0.003 0.0043 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0118 0.0638 0.0638
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0396 0.2542 0.3599
Schistosoma mansoni hypothetical protein 0.0437 0.2819 0.2819
Loa Loa (eye worm) hypothetical protein 0.008 0.0383 0.0501
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0323 0.0738
Brugia malayi PXA domain containing protein 0.0041 0.0113 0.0147
Treponema pallidum NADH oxidase 0.0161 0.0938 0.2528
Giardia lamblia DINP protein human, muc B family 0.0264 0.1641 0.4593
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0233 0.0305
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0092 0.0466 0.0609
Trypanosoma brucei DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Trichomonas vaginalis chromobox protein, putative 0.0148 0.0845 0.1105
Brugia malayi Protein kinase domain containing protein 0.0033 0.0058 0.0076
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0115 0.0618 0.0631
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0119 0.0645 0.0843
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0081 0.0385 0.0504
Echinococcus granulosus beta-adrenergic receptor kinase 0.0041 0.0115 0.0162
Mycobacterium ulcerans 6-phosphofructokinase 0.0115 0.0618 0.0652
Echinococcus multilocularis PHD finger protein rhinoceros 0.0093 0.0467 0.0661
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.004 0.0109 0.0249
Plasmodium falciparum acyl-CoA synthetase 0.006 0.0244 0.0684
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0314 0.1981 0.4533
Plasmodium falciparum SUMO-activating enzyme subunit 1 0.0047 0.0153 0.043
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0201 0.1206 0.2761
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.003 0.0041 0.0116
Loa Loa (eye worm) hypothetical protein 0.0034 0.0067 0.0088
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0172 0.101 0.2828
Treponema pallidum exodeoxyribonuclease (exoA) 0.0058 0.0233 0.053
Trichomonas vaginalis glucosylceramidase, putative 0.0405 0.2602 0.3404
Leishmania major trypanothione reductase 0.0466 0.3018 0.6906
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0043 0.0127 0.0291
Leishmania major NADH dehydrogenase, putative 0.0043 0.0127 0.0291
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0055 0.0212 0.0484
Loa Loa (eye worm) PXA domain-containing protein 0.0041 0.0113 0.0147
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.037 0.236 0.3342
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.008 0.0383 0.0329
Schistosoma mansoni hypothetical protein 0.0033 0.0058 0.0058
Brugia malayi Pip kinase protein 2 0.0688 0.4533 0.5929
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0127 0.0291
Trypanosoma cruzi DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Trichomonas vaginalis glucosylceramidase, putative 0.0384 0.2461 0.3219
Leishmania major hypothetical protein, conserved 0.0054 0.02 0.0458
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0209
Onchocerca volvulus 0.0183 0.1083 0.2088
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0342 0.2169 0.6072
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0344 0.2188 0.6075
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0326 0.2066 0.2492
Entamoeba histolytica recQ family helicase, putative 0.004 0.0105 0.0293
Trypanosoma brucei ubiquitin-activating enzyme E1, putative 0.0031 0.0044 0.0101
Loa Loa (eye worm) hypothetical protein 0.0065 0.0279 0.0364
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0043 0.0127 0.0167
Schistosoma mansoni glutamate synthase 0.0043 0.0127 0.0127
Trichomonas vaginalis dullard protein, putative 0.0027 0.0021 0.0027
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0323 0.0738
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0161 0.0938 0.2146
Echinococcus multilocularis sodium channel protein 0.0168 0.0983 0.1392
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0547 0.3572 0.4428
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0688 0.4533 0.6418
Schistosoma mansoni voltage-gated cation channel 0.0396 0.2542 0.2542
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0192 0.1149 0.1503
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0041 0.0115 0.015
Trichomonas vaginalis glucosylceramidase, putative 0.0586 0.3838 0.5019
Mycobacterium ulcerans fatty-acid-CoA ligase 0.006 0.0244 0.0156
Entamoeba histolytica hypothetical protein 0.0096 0.0489 0.1368
Loa Loa (eye worm) hypothetical protein 0.0047 0.0153 0.0201
Echinococcus multilocularis ubiquitin conjugating enzyme e2 i 0.0024 0.0000044955 0.0000063651
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0113 0.0147
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0348 0.0797
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0043 0.0127 0.018
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0011 0.0016
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0043 0.0127 0.018
Loa Loa (eye worm) ThiF family protein 0.0031 0.0044 0.0058
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0113 0.0159
Trichomonas vaginalis mercuric reductase, putative 0.0161 0.0938 0.1226
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0093 0.0472 0.1081
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.1181 0.7905 1
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0032 0.0054 0.0152
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0304 0.0304
Trypanosoma brucei DNA polymerase kappa, putative 0.0264 0.1641 0.3755
Leishmania major mitochondrial DNA polymerase beta 0.0664 0.4369 1
Trichomonas vaginalis glucosylceramidase, putative 0.0384 0.2461 0.3219
Trichomonas vaginalis bromodomain-containing protein, putative 0.0138 0.0779 0.1018
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0027 0.0021 0.0059
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0051 0.0186 0.0263
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0075 0.0348 0.0797
Echinococcus granulosus peregrin 0.0106 0.0562 0.0795
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0047 0.0062
Echinococcus granulosus sumo-activating enzyme subunit 2 0.0031 0.0044 0.0063
Brugia malayi glutamate synthase 0.0043 0.0127 0.0167
Loa Loa (eye worm) hypothetical protein 0.0145 0.0822 0.1076
Brugia malayi Bromodomain containing protein 0.0106 0.0562 0.0735
Brugia malayi Hemopexin family protein 0.038 0.2432 0.3181
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0342 0.2169 0.2169
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0119 0.0645 0.17
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0075 0.0348 0.0455
Brugia malayi polk-prov protein 0.0158 0.0915 0.1197
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0348 0.0797
Loa Loa (eye worm) hypothetical protein 0.0041 0.0113 0.0147
Loa Loa (eye worm) hypothetical protein 0.0341 0.2167 0.2834
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0233 0.0533
Loa Loa (eye worm) hypothetical protein 0.0081 0.0385 0.0504
Brugia malayi Matrixin family protein 0.0268 0.1666 0.218
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.02 0.0561
Plasmodium falciparum glutathione reductase 0.0161 0.0938 0.2625
Brugia malayi F/Y-rich N-terminus family protein 0.0045 0.0144 0.0188
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0046 0.013
Schistosoma mansoni hypothetical protein 0.0093 0.0467 0.0467
Schistosoma mansoni sex comb on midleg homolog 0.0151 0.0865 0.0865
Leishmania major hypothetical protein, conserved 0.0043 0.0127 0.0291
Schistosoma mansoni sulfide quinone reductase 0.0043 0.0127 0.0127
Echinococcus multilocularis 0.0027 0.0021 0.003
Giardia lamblia Thioredoxin reductase 0.0043 0.0127 0.0357
Plasmodium vivax JmjC domain containing protein 0.0048 0.016 0.0448
Brugia malayi CXXC zinc finger family protein 0.0099 0.051 0.0666
Plasmodium falciparum phosphoglycerate kinase 0.0547 0.3572 1
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0466 0.0609
Schistosoma mansoni hypothetical protein 0.0043 0.0127 0.0127
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0618 0.0808
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0011 0.0016
Echinococcus multilocularis polycomb protein SCMH1 0.0151 0.0865 0.1225
Leishmania major cathepsin L-like protease 0.0071 0.0323 0.0738
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0147 0.0192
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0043 0.0127 0.0357
Entamoeba histolytica hypothetical protein 0.0232 0.1419 0.3973
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0344 0.2188 0.6075
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0096 0.0492 0.1376
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0161 0.0938 0.1042
Echinococcus granulosus Regulator of G protein signaling 20 0.0041 0.0113 0.0159
Echinococcus multilocularis disco interacting protein 2 0.0082 0.0392 0.0555
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0041 0.0115 0.0264
Leishmania major phosphatidylinositol (3,5) kinase, putative 0.0055 0.0212 0.0484
Schistosoma mansoni lipoxygenase 0.0083 0.0402 0.0402
Entamoeba histolytica hypothetical protein 0.0051 0.0186 0.052
Echinococcus granulosus MAM 0.0033 0.0058 0.0082
Echinococcus granulosus axis inhibition protein axin 0.0041 0.0113 0.0159
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0043 0.0127 0.0357
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0046 0.013
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0041 0.0113 0.0147
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0396 0.2542 0.3599
Loa Loa (eye worm) hypothetical protein 0.0137 0.077 0.1007
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0077 0.0362 0.0362
Echinococcus multilocularis transcription factor Dp 1 0.0198 0.1186 0.1679
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0048 0.016 0.016
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0301 0.1891 0.2267
Echinococcus granulosus jumonji domain containing 1A 0.0048 0.016 0.0226
Loa Loa (eye worm) hypothetical protein 0.0027 0.0019 0.0024
Echinococcus multilocularis chromobox protein 1 0.0148 0.0845 0.1196
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0081 0.0385 0.0546
Trypanosoma brucei DNA polymerase IV, putative 0.0306 0.1924 0.4404
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0222 0.0122
Plasmodium falciparum phosphatidylinositol-4-phosphate 5-kinase 0.0055 0.0212 0.0593
Trypanosoma brucei unspecified product 0.0306 0.1924 0.4404
Plasmodium vivax acyl-CoA synthetase, putative 0.006 0.0244 0.0684
Loa Loa (eye worm) RGS-3 protein 0.0041 0.0113 0.0147
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0232 0.1419 0.2009
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0113 0.0147
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0027 0.0021 0.003
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0161 0.0938 0.2625
Echinococcus multilocularis Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0055 0.0212 0.03
Trypanosoma cruzi phosphatidylinositol 4-phosphate 5-kinase alpha, putative 0.0055 0.0212 0.0484
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.02 0.0458
Schistosoma mansoni serine/threonine protein kinase 0.0092 0.0466 0.0466
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0161 0.0938 0.2146
Loa Loa (eye worm) hypothetical protein 0.0138 0.078 0.102
Onchocerca volvulus 0.0783 0.5187 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Schistosoma mansoni protein phosphatase 2C 0.0048 0.016 0.016
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.0348 0.0455
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0027 0.0021 0.0059
Giardia lamblia PHD finger protein 15 0.0093 0.0467 0.1308
Trypanosoma brucei hypothetical protein, conserved 0.0043 0.0127 0.0291
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0314 0.1981 0.4533
Trypanosoma brucei DNA damage repair protein, putative 0.0076 0.0352 0.0805
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0351 0.2234 0.2234
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0081 0.0385 0.0546
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0113 0.0159
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0226 0.1377 0.1607
Echinococcus granulosus PHD finger protein rhinoceros 0.0093 0.0467 0.0661
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0075 0.0348 0.0493
Schistosoma mansoni apoptosis regulator bax 0.0088 0.0439 0.0439
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0077 0.0362 0.0473
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0161 0.0938 0.2146
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0046 0.013
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0547 0.3572 0.4428
Treponema pallidum fructose-bisphosphate aldolase 0.0312 0.1967 0.5448
Loa Loa (eye worm) hypothetical protein 0.0158 0.0915 0.1197
Leishmania major hypothetical protein, conserved 0.0048 0.016 0.0366
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0466 0.0609
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.1149 0.1627
Echinococcus multilocularis regulator of G protein signaling 0.0041 0.0113 0.0159
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0664 0.4369 1
Entamoeba histolytica acyl-coA synthetase, putative 0.008 0.0383 0.1073
Brugia malayi glutaminase DH11.1 0.1143 0.7646 1
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0055 0.0212 0.0212
Toxoplasma gondii small ubiquitin family modifier, putative 0.0033 0.0058 0.0164
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0083 0.0401 0.0773
Loa Loa (eye worm) phosphofructokinase 0.0115 0.0618 0.0808
Toxoplasma gondii aldehyde dehydrogenase 0.0068 0.0299 0.0837
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0234 0.1432 0.4008
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0116 0.0625 0.0885
Brugia malayi jmjC domain containing protein 0.0182 0.108 0.1413
Brugia malayi SET domain containing protein 0.0028 0.0029 0.0038
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0344 0.2188 0.6126
Loa Loa (eye worm) glutaminase 2 0.1143 0.7646 1
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0093 0.0467 0.0467
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0352 0.0805
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0043 0.0127 0.0357
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0822 0.1164
Onchocerca volvulus 0.0341 0.2167 0.4178
Schistosoma mansoni zinc finger protein 0.0034 0.0067 0.0067
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0183 0.1083 0.1416
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0027 0.0021 0.0059
Echinococcus multilocularis phd:f box containing protein 0.0048 0.016 0.0226
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0043 0.0127 0.0291
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0606 0.3976 0.563
Echinococcus multilocularis phosphatidylinositol phosphate 5 kinase type III 0.0055 0.0212 0.03
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1967 0.2572
Chlamydia trachomatis phosphoglycerate kinase 0.0547 0.3572 1
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0041 0.0113 0.0113
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0051 0.0186 0.052
Loa Loa (eye worm) matrixin family protein 0.0595 0.3897 0.5098
Brugia malayi jmjC domain containing protein 0.0048 0.016 0.0209
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0232 0.1419 0.2009
Schistosoma mansoni blooms syndrome DNA helicase 0.0041 0.0115 0.0115
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0113 0.0113
Toxoplasma gondii selenide, water dikinase 0.0043 0.0127 0.0357
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0043 0.0127 0.0167
Loa Loa (eye worm) CXXC zinc finger family protein 0.0099 0.051 0.0666
Brugia malayi PHD-finger family protein 0.0034 0.0067 0.0088
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0113 0.0147
Brugia malayi acetyltransferase, GNAT family protein 0.0464 0.3003 0.3928
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.004 0.0105 0.0293
Trichomonas vaginalis glucosylceramidase, putative 0.0384 0.2461 0.3219
Schistosoma mansoni glutamate synthase 0.0043 0.0127 0.0127
Echinococcus multilocularis lysine specific demethylase 6a 0.0048 0.016 0.0226
Loa Loa (eye worm) hypothetical protein 0.0041 0.0113 0.0147
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.016 0.0209
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0113 0.0113
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0138 0.0779 0.218
Entamoeba histolytica thioredoxin reductase, putative 0.0043 0.0127 0.0357
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0051 0.0186 0.052
Entamoeba histolytica disulphide oxidoreductase, putative 0.0043 0.0127 0.0357
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0041 0.0115 0.015
Entamoeba histolytica ubiquitin like protein 0.0033 0.0058 0.0164
Mycobacterium leprae PROBABLE HYDROLASE 0.0326 0.2066 0.2492
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0618 0.0808
Echinococcus multilocularis tumor protein p63 0.0327 0.2069 0.2929
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0043 0.0127 0.018
Echinococcus granulosus chromobox protein 1 0.0148 0.0845 0.1196
Loa Loa (eye worm) jmjC domain-containing protein 0.0191 0.1141 0.1492
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0233 0.0305
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0048 0.016 0.0448
Brugia malayi Matrixin family protein 0.0268 0.1666 0.218
Echinococcus multilocularis Small ubiquitin modifier 2 0.0033 0.0058 0.0083
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0043 0.0127 0.0357
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0161 0.0938 0.2625
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0116 0.0625 0.0625
Loa Loa (eye worm) pip kinase 1 0.0055 0.0212 0.0277
Loa Loa (eye worm) apoptosis regulator protein 0.0088 0.0439 0.0574
Plasmodium falciparum ferrodoxin reductase-like protein 0.0043 0.0127 0.0357
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0051 0.0186 0.0263
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1967 0.2572
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0027 0.0021 0.0059
Trypanosoma brucei phosphoglycerate kinase 0.0547 0.3572 0.8174
Brugia malayi AF-10 protein 0.003 0.0041 0.0054
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0113 0.0147
Loa Loa (eye worm) hypothetical protein 0.0041 0.0115 0.0151
Echinococcus multilocularis muscleblind protein 0.0145 0.0822 0.1164
Echinococcus multilocularis voltage dependent calcium channel 0.0396 0.2542 0.3599
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0448 0.2899 0.3792
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0088 0.0439 0.0439
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0081 0.0385 0.0504
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.004 0.0109 0.0305
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0115 0.0618 0.0631
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.1149 0.1627
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0233 0.0533
Loa Loa (eye worm) voltage-dependent calcium channel 0.0083 0.0402 0.0525
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0116 0.0625 0.0625
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0348 0.0455
Echinococcus multilocularis Chromobox protein 3 0.0024 0.000000028002 0.000000039647
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0301 0.1891 0.5295
Trichomonas vaginalis DNA helicase recq1, putative 0.0165 0.0963 0.1259
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0048 0.016 0.0366
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-kinase 0.0055 0.0212 0.0593
Echinococcus granulosus CTD small phosphatase protein like 0.0027 0.0021 0.003
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0168 0.0983 0.1392
Loa Loa (eye worm) hypothetical protein 0.0083 0.0401 0.0524
Trichomonas vaginalis glucosylceramidase, putative 0.0405 0.2602 0.3404
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0161 0.0938 0.0938
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0041 0.0095
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0244 0.1501 0.1963
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0152 0.0876 0.0963
Brugia malayi hypothetical protein 0.0232 0.1419 0.1856
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1967 0.2572
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0043 0.0127 0.0291
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0342 0.2169 0.2836
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0046 0.0061
Loa Loa (eye worm) hypothetical protein 0.0059 0.0235 0.0307
Trypanosoma cruzi DNA polymerase eta, putative 0.0402 0.2581 0.5906
Onchocerca volvulus Matrilysin homolog 0.0268 0.1666 0.3213
Echinococcus granulosus ubiquitin conjugating enzyme e2 i 0.0024 0.0000044955 0.0000063651
Echinococcus granulosus transcription factor Dp 1 0.0198 0.1186 0.1679
Echinococcus multilocularis Protein lozenge 0.0059 0.024 0.034
Echinococcus granulosus tumor protein p63 0.0327 0.2069 0.2929
Schistosoma mansoni DNA polymerase eta 0.0402 0.2581 0.2581
Loa Loa (eye worm) hypothetical protein 0.0172 0.1008 0.1318
Entamoeba histolytica phosphoinositide kinase, putative 0.0055 0.0212 0.0593
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0618 0.1414
Onchocerca volvulus Huntingtin homolog 0.0138 0.078 0.1504
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0688 0.4533 0.4533
Trypanosoma cruzi major cysteine proteinase, putative 0.0056 0.0218 0.0499
Brugia malayi Matrixin family protein 0.0268 0.1666 0.218
Mycobacterium ulcerans acyl-CoA synthetase 0.008 0.0383 0.034
Giardia lamblia Hypothetical protein 0.0055 0.0212 0.0593
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0068 0.0299 0.0221
Loa Loa (eye worm) hypothetical protein 0.0078 0.037 0.0483
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0222 0.0122
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0021 0.0048
Treponema pallidum ATP-dependent DNA helicase 0.0041 0.0115 0.0196
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0233 0.0305
Loa Loa (eye worm) hypothetical protein 0.0041 0.0115 0.015
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.006 0.0244 0.0562
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0077 0.0359 0.0509
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0119 0.0645 0.1807
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0075 0.0348 0.0493
Echinococcus multilocularis 6 phosphofructokinase 0.0115 0.0618 0.0875
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0785 0.5197 0.7358
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0233 0.0305
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like protein 0.0055 0.0212 0.0484
Loa Loa (eye worm) bromodomain containing protein 0.003 0.0041 0.0053
Echinococcus granulosus SAM and MBT domain containing protein 0.0151 0.0865 0.1225
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0042 0.0118 0.0118
Brugia malayi Bromodomain containing protein 0.0093 0.0471 0.0616
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0113 0.0147
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.1181 0.7905 1
Loa Loa (eye worm) MBCTL1 0.0172 0.1008 0.1318
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0043 0.0127 0.0167
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0618 0.173
Trypanosoma brucei phosphatidylinositol phosphate kinase alpha 0.0055 0.0212 0.0484
Brugia malayi glutathione reductase 0.0466 0.3018 0.3947
Echinococcus multilocularis SAM and MBT domain containing protein 0.0151 0.0865 0.1225
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.008 0.0383 0.0329
Loa Loa (eye worm) hypothetical protein 0.0048 0.016 0.0209
Brugia malayi serine/threonine-protein kinase plk-2 0.0092 0.0466 0.0609
Plasmodium vivax ataxin-2 like protein, putative 0.0054 0.02 0.0561
Loa Loa (eye worm) hypothetical protein 0.0473 0.3067 0.4011
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0043 0.0127 0.0357
Brugia malayi hypothetical protein 0.0473 0.3067 0.4011
Entamoeba histolytica hypothetical protein 0.0232 0.1419 0.3973
Schistosoma mansoni disulfide oxidoreductase 0.0043 0.0127 0.0127
Brugia malayi jmjC domain containing protein 0.0048 0.016 0.0209
Schistosoma mansoni chromobox protein 0.0148 0.0845 0.0845
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0081 0.0385 0.0546
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0396 0.2542 0.3599
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0055 0.0212 0.0212
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0041 0.0116
Brugia malayi Ubiquitin-like protein SMT3 0.0033 0.0058 0.0076
Echinococcus multilocularis jumonji domain containing protein 0.0129 0.0715 0.1012
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0028 0.0026 0.0037
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0046 0.0061
Plasmodium falciparum thioredoxin reductase 0.0161 0.0938 0.2625
Toxoplasma gondii thioredoxin reductase 0.0466 0.3018 0.8449
Echinococcus multilocularis JmjC domain containing protein 4 0.0048 0.016 0.0226
Toxoplasma gondii hypothetical protein 0.0073 0.0333 0.0933
Onchocerca volvulus 0.003 0.0043 0.0082
Onchocerca volvulus 0.0033 0.0058 0.0112
Schistosoma mansoni glutamate synthase 0.0043 0.0127 0.0127
Schistosoma mansoni amyloid beta A4 protein related 0.0143 0.0808 0.0808
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0233 0.0652
Loa Loa (eye worm) heterochromatin protein 1 0.0148 0.0845 0.1105
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1967 0.2572
Echinococcus granulosus cpg binding protein 0.0103 0.0535 0.0758
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.1149 0.1149
Brugia malayi Thioredoxin reductase 0.0466 0.3018 0.3947
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0114 0.0612 0.14
Trypanosoma cruzi DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0469 0.3042 0.3042
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0113 0.0113
Schistosoma mansoni regulator of G protein signaling 0.0046 0.0151 0.0151
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0092 0.0466 0.1066
Trypanosoma cruzi small ubiquitin protein, putative 0.0033 0.0058 0.0134
Echinococcus multilocularis beta adrenergic receptor kinase 0.0041 0.0115 0.0162
Echinococcus granulosus SUMO activating enzyme subunit 1 0.0047 0.0153 0.0217
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0547 0.3572 1
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0043 0.0127 0.018
Loa Loa (eye worm) glutathione reductase 0.0466 0.3018 0.3947
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0618 0.173
Onchocerca volvulus 0.003 0.0043 0.0082
Plasmodium falciparum histone acetyltransferase GCN5 0.0124 0.0684 0.1915
Trichomonas vaginalis chromobox protein, putative 0.0148 0.0845 0.1105
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0043 0.0127 0.0357
Trypanosoma brucei trypanothione reductase 0.0466 0.3018 0.6906
Mycobacterium ulcerans hydrolase 0.0326 0.2066 0.2578
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0051 0.0186 0.052
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0043 0.0127 0.0167
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0113 0.0159
Trichomonas vaginalis glutaminase, putative 0.1143 0.7646 1
Onchocerca volvulus Huntingtin homolog 0.0138 0.078 0.1504
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0047 0.0062
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0028 0.0026 0.0037
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0055 0.0212 0.0484
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0056
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0344 0.2188 0.3098
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.037 0.236 0.3342
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0077 0.0359 0.0509
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0344 0.2188 0.5983
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0043 0.0127 0.0167
Brugia malayi Bloom's syndrome protein homolog 0.0165 0.0963 0.1259
Loa Loa (eye worm) hypothetical protein 0.0473 0.3067 0.4011
Schistosoma mansoni hypothetical protein 0.003 0.0041 0.0041
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0547 0.3572 0.4671
Loa Loa (eye worm) ube2i2 protein 0.0024 0.0000044955 0.0000058799
Plasmodium vivax DNA repair protein REV1, putative 0.0076 0.0352 0.0985
Trypanosoma brucei NADH dehydrogenase 0.0043 0.0127 0.0291
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.004 0.0109 0.0109
Entamoeba histolytica phosphatidylinositol-4-phosphate 5-kinase, putative 0.0055 0.0212 0.0593
Brugia malayi Matrixin family protein 0.0731 0.4832 0.632
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0043 0.0127 0.0167
Trypanosoma brucei DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0055 0.0212 0.0593
Onchocerca volvulus Matrix metalloproteinase homolog 0.0595 0.3897 0.7514
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0241 0.1482 0.3391
Loa Loa (eye worm) hypothetical protein 0.0088 0.0439 0.0574
Plasmodium vivax ferrodoxin reductase, putative 0.0043 0.0127 0.0357
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0312 0.1967 0.5507
Brugia malayi jmjC domain containing protein 0.037 0.236 0.3087
Brugia malayi ImpB/MucB/SamB family protein 0.0402 0.2581 0.3375
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0046 0.013
Trypanosoma brucei DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Onchocerca volvulus 0.0099 0.051 0.0982
Brugia malayi CHD4 protein 0.0028 0.0026 0.0034
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0547 0.3572 0.8174
Leishmania major hypothetical protein, conserved 0.0043 0.0127 0.0291
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0222 0.0122
Echinococcus granulosus histone lysine methyltransferase setb 0.0118 0.0638 0.0903
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0161 0.0938 0.2528
Loa Loa (eye worm) hypothetical protein 0.0268 0.1666 0.218
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0099 0.0513 0.1437
Plasmodium falciparum glutathione reductase 0.0466 0.3018 0.8449
Echinococcus granulosus regulator of G protein signaling 3 0.0041 0.0113 0.0159
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0116 0.0625 0.0625
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0323 0.0738
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0161 0.0938 0.2146
Brugia malayi A-kinase anchor protein 10, precursor 0.0041 0.0113 0.0147
Trypanosoma brucei DNA polymerase kappa, putative 0.0158 0.0915 0.2094
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0323 0.0738
Onchocerca volvulus 0.0688 0.4533 0.8739
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0161 0.0938 0.2146
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0161 0.0938 0.2146
Trypanosoma brucei DNA polymerase kappa, putative 0.0189 0.1123 0.2571
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0027 0.0021 0.0027
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0027 0.0021 0.0027
Brugia malayi hypothetical protein 0.0341 0.2167 0.2834
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0047 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0083 0.0402 0.0525
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0147 0.0192
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0108 0.0573 0.1606
Leishmania major 4-coumarate:coa ligase-like protein 0.008 0.0383 0.0877
Schistosoma mansoni jumonji/arid domain-containing protein 0.0182 0.108 0.108
Loa Loa (eye worm) CHromoDomain protein family member 0.0028 0.0026 0.0034
Loa Loa (eye worm) hypothetical protein 0.0033 0.0058 0.0076
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0055 0.0212 0.0484
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0043 0.0127 0.0291
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0244 0.1501 0.1501
Plasmodium falciparum phd finger protein, putative 0.0093 0.0467 0.1308
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0161 0.0938 0.2146
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0444 0.0581
Echinococcus granulosus ubiquitin specific protease 41 0.0075 0.0348 0.0493
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0172 0.1008 0.1427
Echinococcus granulosus regulator of G protein signaling 7 0.0041 0.0113 0.0159
Echinococcus granulosus thioredoxin glutathione reductase 0.0468 0.3032 0.4293
Loa Loa (eye worm) hypothetical protein 0.006 0.0244 0.032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0323 0.0738
Entamoeba histolytica hypothetical protein 0.0041 0.0113 0.0315
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.1063 0.7095 0.8958
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0043 0.0127 0.018
Schistosoma mansoni hypothetical protein 0.0088 0.0439 0.0439
Leishmania major hypothetical protein, conserved 0.0043 0.0127 0.0291
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0046 0.013
Schistosoma mansoni phosphoglycerate kinase 0.0547 0.3572 0.3572
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0043 0.0127 0.0291
Loa Loa (eye worm) matrix metalloproteinase 0.0268 0.1666 0.218
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0043 0.0127 0.0357
Brugia malayi AMP-binding enzyme family protein 0.008 0.0383 0.0501
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0041 0.0113 0.0113
Schistosoma mansoni DNA helicase recq5 0.0081 0.0385 0.0385
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0161 0.0938 0.2146
Brugia malayi regulator of G-protein signaling rgs-7 0.0041 0.0113 0.0147
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.1063 0.7095 0.8958
Loa Loa (eye worm) hypothetical protein 0.0093 0.0467 0.0611
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0077 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0043 0.0127 0.0167
Toxoplasma gondii hypothetical protein 0.0119 0.0645 0.1807
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0047 0.0062
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0259 0.0366
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0048 0.016 0.0366
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0043 0.0127 0.0291
Echinococcus granulosus jumonji domain containing protein 0.0129 0.0715 0.1012
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0299 0.0228
Trypanosoma brucei DNA polymerase kappa, putative 0.0158 0.0915 0.2094
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0047 0.0062
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0161 0.0938 0.1226
Plasmodium vivax phosphoglycerate kinase, putative 0.0547 0.3572 1
Echinococcus multilocularis SUMO activating enzyme subunit 2 0.0031 0.0044 0.0063
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0043 0.0127 0.0167
Echinococcus multilocularis glutamate synthase 0.0043 0.0127 0.018
Plasmodium falciparum small ubiquitin-related modifier 0.0033 0.0058 0.0164
Trichomonas vaginalis apoptosis inducing factor, putative 0.0043 0.0127 0.0167
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0055 0.0212 0.0484
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0098 0.0505 0.1155
Trichomonas vaginalis glucosylceramidase, putative 0.0586 0.3838 0.5019
Trypanosoma brucei DNA damage repair protein, putative 0.0076 0.0352 0.0805
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.004 0.0109 0.0305
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0041 0.0113 0.0147
Onchocerca volvulus 0.0043 0.0127 0.0246
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0027 0.0021 0.0027
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0396 0.2542 0.2542
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0075 0.0348 0.0493
Leishmania major DNA polymerase eta, putative 0.0402 0.2581 0.5906
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0323 0.0738
Leishmania major DNA damage repair protein, putative 0.0076 0.0352 0.0805
Brugia malayi SEA domain containing protein 0.003 0.0043 0.0056
Trypanosoma cruzi PAB1-binding protein , putative 0.0054 0.02 0.0458
Trichomonas vaginalis glutathione reductase, putative 0.0161 0.0938 0.1226
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0547 0.3572 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0586 0.3838 0.5019
Leishmania major DNA polymerase kappa, putative 0.0076 0.0352 0.0805
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0161 0.0938 0.2146
Mycobacterium tuberculosis Probable dehydrogenase 0.1063 0.7095 0.8958
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0051 0.0186 0.0075
Echinococcus granulosus histone acetyltransferase KAT2B 0.0138 0.0779 0.1102
Toxoplasma gondii DNA methyltransferase 2, putative 0.004 0.0109 0.0305
Loa Loa (eye worm) mbt repeat family protein 0.0151 0.0865 0.1132
Brugia malayi PHD-finger family protein 0.0093 0.0467 0.0611
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0046 0.0061
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0161 0.0938 0.2625
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0118 0.0638 0.0638
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0043 0.0127 0.0291
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0618 0.0618
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0466 0.3018 0.3716
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0326 0.2064 0.27
Echinococcus granulosus Chromobox protein 3 0.0024 0.000000028002 0.000000039647
Loa Loa (eye worm) hypothetical protein 0.0041 0.0113 0.0147
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0011 0.0011
Brugia malayi FYVE finger-containing phosphoinositide kinase, putative 0.0055 0.0212 0.0277
Onchocerca volvulus 0.0032 0.0052 0.01
Echinococcus multilocularis expressed protein 0.0792 0.5248 0.743
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.0348 0.0455
Plasmodium vivax small ubiquitin-related modifier, putative 0.0033 0.0058 0.0164
Schistosoma mansoni jumonji domain containing protein 0.0048 0.016 0.016
Onchocerca volvulus Serine\/threonine kinase homolog 0.0092 0.0466 0.0898
Schistosoma mansoni lozenge 0.0059 0.024 0.024
Echinococcus granulosus polycomb protein SCMH1 0.0151 0.0865 0.1225
Plasmodium falciparum JmjC domain-containing protein, putative 0.0048 0.016 0.0448
Toxoplasma gondii LsmAD domain-containing protein 0.0054 0.02 0.0561
Giardia lamblia Phosphatidylinositol-4-phosphate 5-kinase, putative 0.0055 0.0212 0.0593
Echinococcus granulosus disco interacting protein 2 0.0082 0.0392 0.0555
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0075 0.0348 0.0348
Trypanosoma cruzi cruzipain precursor, putative 0.0071 0.0323 0.0738
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0093 0.0472 0.1081
Loa Loa (eye worm) hypothetical protein 0.0055 0.0209 0.0273
Onchocerca volvulus 0.003 0.0043 0.0082
Plasmodium vivax phosphatidylinositol-4-phosphate 5-kinase, putative 0.0055 0.0212 0.0593
Schistosoma mansoni chromobox protein 0.0148 0.0845 0.0845
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0192 0.1149 0.1627
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0098 0.0505 0.1155
Giardia lamblia Histone acetyltransferase GCN5 0.0124 0.0684 0.1915
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0203 0.0265
Loa Loa (eye worm) hypothetical protein 0.006 0.0244 0.032
Brugia malayi Phosphoglycerate kinase 0.0547 0.3572 0.4671
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0323 0.0738
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0048 0.016 0.0448
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0119 0.0645 0.1807
Treponema pallidum oxidoreductase 0.0043 0.0127 0.023
Schistosoma mansoni cpg binding protein 0.0103 0.0535 0.0535
Echinococcus granulosus L aminoadipate semialdehyde 0.0183 0.1083 0.1533
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0047 0.0062
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0119 0.0646 0.0914
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0051 0.0186 0.0078
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0618 0.0808
Brugia malayi hypothetical protein 0.0035 0.0071 0.0092
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.1058 0.7063 1
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0055 0.0212 0.0484
Schistosoma mansoni hypothetical protein 0.0929 0.618 0.618
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0043 0.0127 0.018
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0075 0.0348 0.0348
Loa Loa (eye worm) hypothetical protein 0.008 0.0383 0.0501
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0151 0.0865 0.0865
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0466 0.0609
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0396 0.2542 0.3599
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0323 0.0738
Echinococcus granulosus Small ubiquitin modifier 2 0.0033 0.0058 0.0083
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.006 0.0244 0.015
Trypanosoma cruzi phosphatidylinositol (3,5) kinase, putative 0.0055 0.0212 0.0484
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0201 0.1206 0.2761
Loa Loa (eye worm) hypothetical protein 0.0138 0.078 0.102
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0041 0.0113 0.0159
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0119 0.0646 0.0914
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.008 0.0383 0.0329
Schistosoma mansoni sulfide quinone reductase 0.0043 0.0127 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0113 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0236 0.0308
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0241 0.1482 0.3391
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0081 0.0385 0.1079
Trypanosoma brucei DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Loa Loa (eye worm) hypothetical protein 0.0151 0.0865 0.1132
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0062 0.0259 0.0169
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0054 0.0152
Loa Loa (eye worm) X11 protein 0.0143 0.0808 0.1057
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0233 0.0141
Loa Loa (eye worm) hypothetical protein 0.003 0.0043 0.0056
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1967 0.2572
Trypanosoma cruzi NADH dehydrogenase, putative 0.0043 0.0127 0.0291
Echinococcus multilocularis DNA methyltransferase 2, putative 0.004 0.0109 0.0154
Trichomonas vaginalis glutamate synthase, putative 0.0043 0.0127 0.0167
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0233 0.0533
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1967 0.2572
Schistosoma mansoni sex comb on midleg homolog 0.0151 0.0865 0.0865
Loa Loa (eye worm) hypothetical protein 0.0041 0.0113 0.0147
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0082 0.0392 0.0392
Schistosoma mansoni jumonji/arid domain-containing protein 0.0182 0.108 0.108
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0046 0.013
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0043 0.0127 0.0291
Echinococcus multilocularis voltage dependent calcium channel 0.0396 0.2542 0.3599
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0161 0.0938 0.2625
Schistosoma mansoni phosphoglycerate kinase 0.0547 0.3572 0.3572
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0342 0.2169 0.3071
Schistosoma mansoni blooms syndrome DNA helicase 0.0124 0.0682 0.0682
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0119 0.0645 0.0666
Echinococcus multilocularis peptidase Clp (S14 family) 0.0226 0.1377 0.195
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0301 0.1891 0.2346
Brugia malayi ube2i2 protein 0.0024 0.0000044955 0.0000058799
Echinococcus multilocularis dnaJ subfamily B 0.0437 0.2819 0.3992
Echinococcus granulosus voltage dependent calcium channel 0.0396 0.2542 0.3599
Loa Loa (eye worm) pip kinase 2 0.0688 0.4533 0.5929
Toxoplasma gondii histone lysine methyltransferase SET1 0.0076 0.0351 0.0983
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0088 0.0439 0.0621
Loa Loa (eye worm) hypothetical protein 0.0396 0.2542 0.3325
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0043 0.0127 0.0167
Brugia malayi Pre-SET motif family protein 0.0688 0.4538 0.5935
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0233 0.0533
Brugia malayi regulator of G-protein signaling egl-10 0.0041 0.0113 0.0147
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0161 0.0938 0.2625
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0226 0.1377 0.1607
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0043 0.0127 0.018
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0118 0.0638 0.0903
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0323 0.0738
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0201 0.1206 0.2761
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0068 0.0299 0.0424
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0688 0.4533 0.4533
Brugia malayi mbt repeat family protein 0.0151 0.0865 0.1132
Onchocerca volvulus 0.003 0.0043 0.0082
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0046 0.0061
Mycobacterium ulcerans acyl-CoA synthetase 0.008 0.0383 0.034
Entamoeba histolytica hypothetical protein 0.0041 0.0113 0.0315
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0081 0.0385 0.1079
Plasmodium vivax SET domain protein, putative 0.0099 0.0513 0.1437
Brugia malayi AMP-binding enzyme family protein 0.008 0.0383 0.0501
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0688 0.4538 0.5935
Schistosoma mansoni ubiquitin-conjugating enzyme E2 I 0.0024 0.0000044955 0.0000044955
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0161 0.0938 0.1328
Leishmania major hypothetical protein, conserved 0.0027 0.0021 0.0048
Entamoeba histolytica phosphofructokinase, putative 0.0115 0.0618 0.173
Brugia malayi ImpB/MucB/SamB family protein 0.0244 0.1501 0.1963
Schistosoma mansoni ap endonuclease 0.0058 0.0233 0.0233
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0464 0.3003 0.3003
Echinococcus multilocularis histone acetyltransferase MYST2 0.0172 0.1008 0.1427
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0352 0.0805
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0043 0.0127 0.0357
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0259 0.0175
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0342 0.2169 0.4963
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0068 0.0299 0.0424
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0116 0.0625 0.0885
Brugia malayi Bromodomain containing protein 0.0052 0.0191 0.025
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0244 0.1501 0.2125
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0344 0.2188 0.6075
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0115 0.0618 0.1414
Brugia malayi AMP-binding enzyme family protein 0.008 0.0383 0.0501
Schistosoma mansoni phosphatidylinositol-4-phosphate-5-kinaseputativ e 0.0055 0.0212 0.0212
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0075 0.0348 0.0975
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0352 0.0805
Onchocerca volvulus 0.038 0.2432 0.4689
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.016 0.0209
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0099 0.0513 0.0727
Loa Loa (eye worm) hypothetical protein 0.0344 0.2188 0.2862
Schistosoma mansoni hypothetical protein 0.0088 0.0439 0.0439
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0152 0.0876 0.0963
Plasmodium vivax hypothetical protein, conserved 0.0093 0.0467 0.1308
Echinococcus granulosus 6 phosphofructokinase 0.0115 0.0618 0.0875
Echinococcus granulosus expressed protein 0.0792 0.5248 0.743
Leishmania major ATP-dependent phosphofructokinase 0.0115 0.0618 0.1414
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0618 0.0808
Schistosoma mansoni axis inhibition protein axin 0.0041 0.0113 0.0113
Trypanosoma brucei unspecified product 0.0168 0.0984 0.2251
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0264 0.1641 0.1945
Echinococcus multilocularis MAM 0.0033 0.0058 0.0082
Loa Loa (eye worm) hypothetical protein 0.006 0.0244 0.032
Loa Loa (eye worm) glutaminase 0.1143 0.7646 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0323 0.0738
Brugia malayi hypothetical protein 0.0033 0.0058 0.0076
Loa Loa (eye worm) hypothetical protein 0.0145 0.0822 0.1076
Loa Loa (eye worm) hypothetical protein 0.0033 0.0058 0.0076
Leishmania major phosphoglycerate kinase B, cytosolic 0.0547 0.3572 0.8174
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0075 0.0348 0.0975
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0161 0.0938 0.2146
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0096 0.0489 0.1368
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0323 0.0738
Schistosoma mansoni kinase 0.0047 0.0155 0.0155
Echinococcus granulosus lysine specific demethylase 6a 0.0048 0.016 0.0226
Brugia malayi chromobox protein homolog 3 0.0083 0.0401 0.0524
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0062 0.0259 0.0366
Trypanosoma cruzi trypanothione reductase, putative 0.0161 0.0938 0.2146
Trichomonas vaginalis glucosylceramidase, putative 0.0586 0.3838 0.5019
Loa Loa (eye worm) hypothetical protein 0.0048 0.0162 0.0211
Trypanosoma cruzi DNA damage repair protein, putative 0.0076 0.0352 0.0805
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0301 0.1891 0.2267
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0161 0.0938 0.1078
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0161 0.0938 0.2146
Echinococcus granulosus lysine specific demethylase 5A 0.0182 0.108 0.1529
Leishmania major 4-coumarate:coa ligase-like protein 0.008 0.0383 0.0877
Trichomonas vaginalis glucosylceramidase, putative 0.0384 0.2461 0.3219
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0027 0.0021 0.0027
Loa Loa (eye worm) hypothetical protein 0.0041 0.0113 0.0147
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0068 0.0299 0.0684
Loa Loa (eye worm) thioredoxin reductase 0.0466 0.3018 0.3947
Loa Loa (eye worm) hypothetical protein 0.0183 0.1083 0.1416
Brugia malayi jmjC domain containing protein 0.0048 0.016 0.0209
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0043 0.0127 0.018
Echinococcus granulosus bloom syndrome protein 0.0165 0.0963 0.1363
Trypanosoma cruzi hypothetical protein, conserved 0.0043 0.0127 0.0291
Trypanosoma brucei DNA polymerase eta, putative 0.0402 0.2581 0.5906
Trichomonas vaginalis glucosylceramidase, putative 0.0586 0.3838 0.5019
Loa Loa (eye worm) TK/ALK protein kinase 0.0033 0.0058 0.0076
Mycobacterium leprae conserved hypothetical protein 0.0051 0.0186 0.0075
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0055 0.0212 0.0277
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0396 0.2542 0.2542
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0401 0.0524
Echinococcus granulosus voltage dependent calcium channel 0.0083 0.0402 0.0569
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0299 0.0299
Leishmania major cathepsin L-like protease 0.0071 0.0323 0.0738
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0081 0.0385 0.0546
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0113 0.0147
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0344 0.2188 0.2649
Loa Loa (eye worm) jmjC domain-containing protein 0.0182 0.108 0.1413
Leishmania major phosphopantetheinyl transferase-like protein 0.0051 0.0186 0.0425
Loa Loa (eye worm) PHD-finger family protein 0.0093 0.0467 0.0611
Schistosoma mansoni transcription factor LCR-F1 0.0232 0.1419 0.1419
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0116 0.0625 0.0625
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0344 0.2188 0.2741
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0688 0.4533 0.6418
Loa Loa (eye worm) SMO-1 protein 0.0033 0.0058 0.0076
Trypanosoma brucei hypothetical protein, conserved 0.0051 0.0186 0.0425
Giardia lamblia Sgs1 DNA helicase, putative 0.0081 0.0385 0.1079
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0043 0.0127 0.0357
Trypanosoma brucei DNA polymerase IV, putative 0.0326 0.2064 0.4724
Mycobacterium ulcerans hypothetical protein 0.008 0.0383 0.034
Trypanosoma brucei DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Echinococcus granulosus histone acetyltransferase KAT2B 0.0448 0.2897 0.4102
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0097 0.0137
Schistosoma mansoni z-protein (S1r protein) 0.0041 0.0113 0.0113
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0586 0.3838 0.5019
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0466 0.0609
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0161 0.0938 0.2146
Giardia lamblia Sentrin 0.0033 0.0058 0.0163
Trichomonas vaginalis dullard protein, putative 0.0027 0.0021 0.0027
Giardia lamblia Kinase, PLK 0.0092 0.0466 0.1304
Trypanosoma brucei phosphoglycerate kinase 0.0201 0.1206 0.2761
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0088 0.0439 0.0621
Loa Loa (eye worm) runx1 0.0059 0.024 0.0314
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.1149 0.1149
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0026 0.0015 0.0034
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0299 0.0228
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0323 0.0738
Brugia malayi Pre-SET motif family protein 0.0099 0.0513 0.0671
Trypanosoma brucei DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0344 0.2188 0.6126
Schistosoma mansoni hypothetical protein 0.0033 0.0058 0.0058
Loa Loa (eye worm) calcium channel 0.0396 0.2542 0.3325
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0022 0.0029
Toxoplasma gondii hypothetical protein 0.0047 0.0153 0.043
Schistosoma mansoni ubiquitin-activating enzyme E1b 0.0031 0.0044 0.0044
Brugia malayi Muscle positioning protein 4 0.003 0.0043 0.0056
Brugia malayi ThiF family protein 0.0047 0.0153 0.0201
Leishmania major phosphoglycerate kinase C, glycosomal 0.0547 0.3572 0.8174
Trichomonas vaginalis glutamate synthase, putative 0.0043 0.0127 0.0167
Leishmania major phosphatidylinositol-4-phosphate-5-kinase-likep ro tein 0.0055 0.0212 0.0484
Schistosoma mansoni cpg binding protein 0.0099 0.051 0.051
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0172 0.1008 0.1427
Mycobacterium tuberculosis Conserved hypothetical protein 0.035 0.2223 0.2695
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0161 0.0938 0.2146
Trypanosoma cruzi trypanothione reductase, putative 0.0466 0.3018 0.6906
Onchocerca volvulus Glucosylceramidase homolog 0.0384 0.2461 0.4745
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0055 0.0212 0.0593
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0233 0.033
Leishmania major modification methylase-like protein 0.004 0.0109 0.0249
Schistosoma mansoni jumonji domain containing protein 0.0307 0.1934 0.1934
Onchocerca volvulus 0.0268 0.1666 0.3213
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0046 0.0061
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0161 0.0938 0.2352
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0113 0.0113
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0041 0.0115 0.0323
Plasmodium vivax thioredoxin reductase, putative 0.0466 0.3018 0.8449
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0043 0.0127 0.0357
Trypanosoma cruzi DNA damage repair protein, putative 0.0076 0.0352 0.0805
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0097 0.0137
Schistosoma mansoni hypothetical protein 0.0232 0.1419 0.1419
Loa Loa (eye worm) hypothetical protein 0.0075 0.0348 0.0455
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.016 0.0209
Trypanosoma cruzi NADH dehydrogenase, putative 0.0043 0.0127 0.0291
Echinococcus multilocularis amyloid beta A4 protein 0.0143 0.0808 0.1145
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0138 0.0779 0.218
Trypanosoma brucei phosphoglycerate kinase 0.0547 0.3572 0.8174
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0043 0.0127 0.0167
Brugia malayi 6-phosphofructokinase 0.0115 0.0618 0.0808
Loa Loa (eye worm) FYVE finger-containing phosphoinositide kinase 0.0055 0.0212 0.0277
Toxoplasma gondii PHD-finger domain-containing protein 0.0093 0.0467 0.1308
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0172 0.1008 0.1318
Echinococcus granulosus Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0055 0.0212 0.03
Onchocerca volvulus 0.008 0.0383 0.0739
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0161 0.0938 0.1078
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0055 0.0212 0.0484
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0089 0.0444 0.0856
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0161 0.0938 0.2146
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0081 0.0385 0.1079
Leishmania major DNA polymerase kappa, putative 0.0264 0.1641 0.3755
Schistosoma mansoni phd/f-box containing protein 0.0048 0.016 0.016
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0027 0.0021 0.0059
Trichomonas vaginalis glucosylceramidase, putative 0.0384 0.2461 0.3219
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0027 0.0021 0.0059
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0466 0.0609
Echinococcus multilocularis ubiquitin specific protease 41 0.0075 0.0348 0.0493
Entamoeba histolytica hypothetical protein 0.0041 0.0113 0.0315
Trypanosoma cruzi ubiquitin-activating enzyme, putative 0.0031 0.0044 0.0101
Toxoplasma gondii exonuclease III APE 0.0058 0.0233 0.0652
Plasmodium falciparum SUMO-activating enzyme subunit 2 0.0031 0.0044 0.0124
Schistosoma mansoni hypothetical protein 0.0027 0.0019 0.0019
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0113 0.0159
Brugia malayi PXA domain containing protein 0.0041 0.0113 0.0147
Trypanosoma brucei chrX additional, unordered contigs 0.0076 0.0352 0.0805
Trypanosoma brucei small ubiquitin-related modifier 0.0033 0.0058 0.0134
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.0027
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.1063 0.7095 0.8958
Schistosoma mansoni hypothetical protein 0.0195 0.1165 0.1165
Schistosoma mansoni lipoxygenase 0.0119 0.0646 0.0646
Echinococcus granulosus JmjC domain containing protein 4 0.0048 0.016 0.0226
Schistosoma mansoni myelin transcription factor 1 myt1 0.0172 0.1008 0.1008
Giardia lamblia DNA damage repair protein 0.0076 0.0352 0.0985
Loa Loa (eye worm) hypothetical protein 0.0033 0.0058 0.0076
Onchocerca volvulus Matrilysin homolog 0.0678 0.4465 0.8609
Toxoplasma gondii hypothetical protein 0.0107 0.0566 0.1585
Trichomonas vaginalis set domain proteins, putative 0.0783 0.5187 0.6784
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0161 0.0938 0.1328
Mycobacterium ulcerans DNA polymerase IV 0.0326 0.2064 0.2576
Entamoeba histolytica hypothetical protein 0.0232 0.1419 0.3973
Entamoeba histolytica deoxycytidyl transferase, putative 0.0244 0.1501 0.4202
Mycobacterium ulcerans hypothetical protein 0.035 0.2223 0.2788
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0115 0.0115
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0041 0.0115 0.0264
Entamoeba histolytica acetyltransferase, GNAT family 0.0124 0.0684 0.1915
Entamoeba histolytica phosphoglycerate kinase, putative 0.0547 0.3572 1
Brugia malayi mbt repeat family protein 0.0151 0.0865 0.1132
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0396 0.2542 0.3599
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0352 0.0805
Loa Loa (eye worm) matrixin family protein 0.0731 0.4832 0.632
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0115 0.0618 0.1622
Brugia malayi 6-phosphofructokinase 0.0115 0.0618 0.0808
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0342 0.2169 0.3071
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0047 0.0062
Loa Loa (eye worm) hypothetical protein 0.0688 0.4533 0.5929
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0116 0.0625 0.0885
Echinococcus multilocularis zinc finger protein 0.0034 0.0067 0.0094
Entamoeba histolytica recQ family DNA helicase 0.0041 0.0115 0.0323
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0076 0.0352 0.0985
Trypanosoma brucei polo-like protein kinase 0.0092 0.0466 0.1066
Schistosoma mansoni aldehyde dehydrogenase 0.0068 0.0299 0.0299
Echinococcus granulosus geminin 0.0195 0.1165 0.1649
Trichomonas vaginalis glucosylceramidase, putative 0.0384 0.2461 0.3219
Mycobacterium ulcerans aldehyde dehydrogenase 0.0068 0.0299 0.0228
Echinococcus multilocularis L aminoadipate semialdehyde 0.0183 0.1083 0.1533
Giardia lamblia Glutamate synthase 0.0043 0.0127 0.0357
Schistosoma mansoni ap endonuclease 0.0058 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0268 0.1666 0.218
Echinococcus multilocularis lysine specific demethylase 5A 0.0178 0.1054 0.1492
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0041 0.0113 0.0159
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0088 0.0439 0.0621
Brugia malayi Heterochromatin protein 1 0.0148 0.0845 0.1105
Trypanosoma cruzi DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Mycobacterium tuberculosis Probable oxidoreductase 0.1181 0.7905 1
Brugia malayi Matrixin family protein 0.0268 0.1666 0.218
Entamoeba histolytica serine/threonine protein kinase, putative 0.0092 0.0466 0.1304
Onchocerca volvulus 0.0078 0.037 0.0713
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0192 0.1149 0.1503
Echinococcus granulosus dnaJ subfamily B 0.0437 0.2819 0.3992
Mycobacterium ulcerans acyl-CoA synthetase 0.008 0.0383 0.034
Echinococcus multilocularis dna polymerase eta 0.0402 0.2581 0.3654
Loa Loa (eye worm) RecQ helicase 0.0165 0.0963 0.1259
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0051 0.0186 0.0396
Plasmodium vivax ubiquitin activating enzyme, putative 0.0047 0.0153 0.043
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0043 0.0127 0.0357
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0138 0.0779 0.1018
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0043 0.0127 0.0167
Plasmodium vivax glutathione reductase, putative 0.0466 0.3018 0.8449
Schistosoma mansoni peptidase Clp (S14 family) 0.0344 0.2188 0.2188
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0055 0.0212 0.0484
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.1063 0.7095 0.8958
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0119 0.0645 0.0843
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0043 0.0127 0.0357
Brugia malayi hypothetical protein 0.0054 0.02 0.0262
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0547 0.3572 0.4671
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0062 0.0259 0.0338
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0344 0.2188 0.6126
Schistosoma mansoni 6-phosphofructokinase 0.0115 0.0618 0.0618
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0046 0.013
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0344 0.2188 0.6126
Trichomonas vaginalis glucosylceramidase, putative 0.0586 0.3838 0.5019
Trypanosoma brucei DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Giardia lamblia Phosphoglycerate kinase 0.0547 0.3572 1
Plasmodium vivax hypothetical protein, conserved 0.0055 0.0212 0.0593
Schistosoma mansoni glutaminase 0.1143 0.7646 0.7646
Trypanosoma brucei DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0062 0.0259 0.0592
Mycobacterium tuberculosis Putative ferredoxin reductase 0.1063 0.7095 0.8958
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0113 0.0159
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0342 0.2169 0.2836
Brugia malayi Phosphoglycerate kinase 0.0201 0.1206 0.1578
Onchocerca volvulus 0.003 0.0043 0.0082
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0043 0.0127 0.0357
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0342 0.2169 0.4963
Loa Loa (eye worm) 6-phosphofructokinase 0.0115 0.0618 0.0808
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0344 0.2188 0.3098
Trichomonas vaginalis phosphofructokinase, putative 0.0115 0.0618 0.0808
Schistosoma mansoni bromodomain containing protein 0.0081 0.0385 0.0385
Echinococcus granulosus muscleblind protein 0.0145 0.0822 0.1164
Giardia lamblia Fructose-bisphosphate aldolase 0.0312 0.1967 0.5507
Brugia malayi jmjC domain containing protein 0.0048 0.016 0.0209
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0547 0.3572 0.8174
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0396 0.2542 0.3599
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0323 0.0738
Loa Loa (eye worm) hypothetical protein 0.0176 0.104 0.136
Schistosoma mansoni sumo-1-activating enzyme E1a 0.0042 0.0124 0.0124
Brugia malayi ThiF family protein 0.0031 0.0044 0.0058
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0047 0.0062
Entamoeba histolytica acyl-CoA synthetase, putative 0.008 0.0383 0.1073
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0041 0.0115 0.015
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0161 0.0938 0.2352
Echinococcus granulosus histone acetyltransferase MYST2 0.0172 0.1008 0.1427
Toxoplasma gondii transporter, cation channel family protein 0.0083 0.0402 0.1124
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0244 0.1501 0.2125
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0098 0.0505 0.1155
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0547 0.3572 1
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type I 0.0055 0.0212 0.0212
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0606 0.3976 0.563
Trypanosoma cruzi DNA polymerase eta, putative 0.0234 0.1432 0.3276
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0043 0.0127 0.0291
Onchocerca volvulus 0.0033 0.0058 0.0112
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0233 0.0136
Onchocerca volvulus 0.0473 0.3067 0.5913
Mycobacterium tuberculosis Conserved hypothetical protein 0.0244 0.1501 0.1766
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0051 0.0186 0.0078
Plasmodium falciparum thioredoxin reductase 0.0466 0.3018 0.8449
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0183 0.1083 0.1083
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0301 0.1891 0.5295
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.008 0.0383 0.0329
Trypanosoma brucei phosphatidylinositol (3,5) kinase, putative 0.0055 0.0212 0.0484
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0314 0.1981 0.4533
Brugia malayi Muscleblind-like protein 0.0145 0.0822 0.1076
Entamoeba histolytica acyl-CoA synthetase, putative 0.008 0.0383 0.1073
Onchocerca volvulus 0.0048 0.0162 0.0312
Loa Loa (eye worm) programmed cell death 8 0.0043 0.0127 0.0167
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0046 0.0129
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0027 0.0021 0.0027
Loa Loa (eye worm) hypothetical protein 0.0351 0.2234 0.2923
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0027 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0547 0.3572 0.4671
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.0348 0.0797
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0161 0.0938 0.1078
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.004 0.0109 0.0305
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0027 0.0021 0.003
Echinococcus multilocularis peregrin 0.0106 0.0562 0.0795
Toxoplasma gondii hypothetical protein 0.0172 0.101 0.2828
Trypanosoma brucei phosphoglycerate kinase, putative 0.0201 0.1206 0.2761
Trichomonas vaginalis glucosylceramidase, putative 0.0384 0.2461 0.3219
Brugia malayi Disco-interacting protein 2 homolog 0.0078 0.037 0.0483
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.008 0.0383 0.034
Echinococcus multilocularis axis inhibition protein axin 0.0041 0.0113 0.0159
Mycobacterium tuberculosis Probable reductase 0.1063 0.7095 0.8958
Loa Loa (eye worm) hypothetical protein 0.0118 0.0638 0.0834
Giardia lamblia NADH oxidase lateral transfer candidate 0.0161 0.0938 0.2625
Echinococcus granulosus peptidase Clp S14 family 0.0226 0.1377 0.195
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0043 0.0127 0.018
Schistosoma mansoni hypothetical protein 0.003 0.0043 0.0043
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0027 0.0021 0.0048
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.008 0.0383 0.034
Loa Loa (eye worm) hypothetical protein 0.0041 0.0113 0.0147
Loa Loa (eye worm) hypothetical protein 0.008 0.0383 0.0501
Entamoeba histolytica hypothetical protein 0.0232 0.1419 0.3973
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0201 0.1206 0.2761
Trichomonas vaginalis ubiquitin-conjugating enzyme rad6, putative 0.0024 0.0000044955 0.0000058799
Trichomonas vaginalis glucosylceramidase, putative 0.0586 0.3838 0.5019
Trichomonas vaginalis DNA polymerase eta, putative 0.0326 0.2064 0.27
Echinococcus multilocularis jumonji domain containing 1A 0.0048 0.016 0.0226
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0092 0.0466 0.066
Mycobacterium ulcerans fatty-acid-CoA ligase 0.008 0.0383 0.034
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0048 0.016 0.0366
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0093 0.0472 0.1081
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0466 0.1066
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0336 0.2134 0.5974
Mycobacterium ulcerans DNA polymerase IV 0.0326 0.2064 0.2576
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0055 0.0212 0.0277
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0152 0.0876 0.0996
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0081 0.0385 0.0504
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0323 0.0738
Loa Loa (eye worm) hypothetical protein 0.0073 0.0333 0.0436
Echinococcus multilocularis bloom syndrome protein 0.0165 0.0963 0.1363
Toxoplasma gondii melibiase subfamily protein 0.0116 0.0625 0.175
Echinococcus granulosus dna polymerase eta 0.0402 0.2581 0.3654
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0025 0.0033
Plasmodium vivax SUMO-activating enzyme subunit 2, putative 0.0031 0.0044 0.0124
Echinococcus multilocularis Regulator of G protein signaling 20 0.0041 0.0113 0.0159
Echinococcus granulosus glutamate synthase 0.0043 0.0127 0.018
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0046 0.0061
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0043 0.0127 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0236 0.0308
Treponema pallidum thioredoxin reductase (trxB) 0.0043 0.0127 0.023
Onchocerca volvulus Alhambra homolog 0.0093 0.0467 0.0901
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0051 0.0186 0.0169
Loa Loa (eye worm) hypothetical protein 0.0076 0.0351 0.0459
Loa Loa (eye worm) hypothetical protein 0.0326 0.2066 0.2702
Schistosoma mansoni hypothetical protein 0.0088 0.0439 0.0439
Treponema pallidum phosphoglycerate kinase 0.0547 0.3572 1
Entamoeba histolytica recQ family helicase, putative 0.0098 0.0505 0.1413
Echinococcus multilocularis regulator of G protein signaling 7 0.0041 0.0113 0.0159
Trichomonas vaginalis DNA helicase recq, putative 0.0165 0.0963 0.1259
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0043 0.0127 0.018
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0192 0.1149 0.1627
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0233 0.033
Trypanosoma brucei unspecified product 0.0168 0.0984 0.2251
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0043 0.0127 0.0167
Echinococcus granulosus phd:f box containing protein 0.0048 0.016 0.0226
Loa Loa (eye worm) hypothetical protein 0.0402 0.2581 0.3375
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0466 0.0609
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.004 0.0109 0.0305
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0107 0.0563 0.1576
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.003 0.0041 0.0095
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0664 0.4369 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1967 0.2572
Echinococcus granulosus zinc finger protein 0.0034 0.0067 0.0094
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0055 0.0212 0.0484
Brugia malayi phosphofructokinase 0.0115 0.0618 0.0808
Trichomonas vaginalis dullard protein, putative 0.0027 0.0021 0.0027
Echinococcus granulosus DNA methyltransferase 2, putative 0.004 0.0109 0.0154
Trichomonas vaginalis CAMK family protein kinase 0.0092 0.0466 0.0609
Leishmania major DNA polymerase eta, putative 0.0234 0.1432 0.3276
Leishmania major cathepsin L-like protease 0.0071 0.0323 0.0738
Brugia malayi PHD-finger family protein 0.004 0.0106 0.0138
Leishmania major ubiquitin-activating enzyme-like protein 0.0031 0.0044 0.0101
Loa Loa (eye worm) FYVE zinc finger family protein 0.0055 0.0212 0.0277
Treponema pallidum hypothetical protein 0.0301 0.1891 0.5233
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0162 0.0162
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.008 0.0383 0.034
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0051 0.0186 0.0396
Plasmodium falciparum DNA repair protein REV1, putative 0.0076 0.0352 0.0985
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0148 0.0843 0.2362
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0264 0.1641 0.3755
Loa Loa (eye worm) hypothetical protein 0.006 0.0244 0.032
Trypanosoma brucei DNA polymerase kappa, putative 0.0189 0.1123 0.2571
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0161 0.0938 0.2146
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0062 0.0259 0.0175
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0344 0.2188 0.2741
Schistosoma mansoni regulator of G protein signaling 0.0041 0.0113 0.0113
Brugia malayi Melibiase family protein 0.0077 0.0362 0.0473
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0664 0.4369 1
Onchocerca volvulus 0.0151 0.0865 0.1668
Brugia malayi Probable ClpP-like protease 0.0344 0.2188 0.2862
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0113 0.0159
Echinococcus granulosus amyloid beta A4 protein 0.0143 0.0808 0.1145
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0464 0.3003 0.4252
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0043 0.0127 0.0357
Echinococcus multilocularis regulator of G protein signaling 3 0.0041 0.0113 0.0159
Schistosoma mansoni DNA polymerase IV / kappa 0.0076 0.0352 0.0352
Trypanosoma brucei PAB1-binding protein , putative 0.0054 0.02 0.0458
Schistosoma mansoni cpg binding protein 0.0103 0.0535 0.0535
Schistosoma mansoni phosphatidylserine receptor 0.0048 0.016 0.016
Brugia malayi hypothetical protein 0.0137 0.077 0.1007
Echinococcus granulosus dna polymerase kappa 0.0326 0.2064 0.2923
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.1058 0.7063 1
Schistosoma mansoni hypothetical protein 0.038 0.2432 0.2432
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0123 0.0679 0.0679
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0062 0.0259 0.0259
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0043 0.0127 0.0357
Brugia malayi Regulator of G protein signaling domain containing protein 0.0041 0.0113 0.0147
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0326 0.2066 0.2702
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0473
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0201 0.1206 0.2761
Trypanosoma brucei DNA polymerase IV, putative 0.0326 0.2064 0.4724
Schistosoma mansoni hypothetical protein 0.0195 0.1165 0.1165
Trypanosoma cruzi small ubiquitin protein, putative 0.0033 0.0058 0.0134
Mycobacterium ulcerans hypothetical protein 0.0076 0.0352 0.0298
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase type II beta, putative 0.0055 0.0212 0.0484
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0233 0.0652
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0043 0.0127 0.0291
Trichomonas vaginalis chromobox protein, putative 0.0089 0.0444 0.0581
Plasmodium falciparum ataxin-2 like protein, putative 0.0054 0.02 0.0561
Mycobacterium ulcerans glutaminase 0.1143 0.7646 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0092 0.0466 0.1066
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0057 0.0222 0.0122
Echinococcus granulosus chromobox protein 1 0.0148 0.0845 0.1196
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0127 0.0706 0.0923
Mycobacterium ulcerans phosphoglycerate kinase 0.0547 0.3572 0.4581
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0099 0.0513 0.0513
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0201 0.1206 0.2761
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0396 0.2542 0.3599
Toxoplasma gondii ThiF family protein 0.0031 0.0044 0.0124
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0342 0.2169 0.4963
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0312 0.1967 0.5507
Echinococcus multilocularis SUMO activating enzyme subunit 1 0.0047 0.0153 0.0217
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0043 0.0127 0.0167
Trichomonas vaginalis conserved hypothetical protein 0.0083 0.0401 0.0524
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0088 0.0439 0.0574
Loa Loa (eye worm) acetyltransferase 0.0464 0.3003 0.3928
Echinococcus multilocularis dna polymerase kappa 0.0326 0.2064 0.2923
Leishmania major 4-coumarate:coa ligase-like protein 0.008 0.0383 0.0877
Loa Loa (eye worm) hypothetical protein 0.006 0.0244 0.032
Echinococcus multilocularis thioredoxin glutathione reductase 0.0468 0.3032 0.4293
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0226 0.1377 0.1607
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0138 0.0779 0.218
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0043 0.0127 0.0291
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0088 0.0439 0.0621
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0027 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0054 0.02 0.0262
Echinococcus multilocularis phosphoglycerate kinase 1 0.0547 0.3572 0.5057
Leishmania major small ubiquitin protein, putative 0.0033 0.0058 0.0134
Toxoplasma gondii NADPH-glutathione reductase 0.0161 0.0938 0.2625
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0043 0.0127 0.018
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0065 0.028 0.0641
Brugia malayi hypothetical protein 0.0138 0.078 0.102
Schistosoma mansoni DNA helicase recq1 0.0081 0.0385 0.0385
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0093 0.0472 0.1081
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0047 0.0062
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.1181 0.7905 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0028 0.0026 0.0026
Echinococcus granulosus phosphatidylinositol phosphate 5 kinase type III 0.0055 0.0212 0.03
Trypanosoma cruzi DNA polymerase kappa, putative 0.0326 0.2064 0.4724
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0043 0.0127 0.018
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0095 0.0484 0.0685
Loa Loa (eye worm) hypothetical protein 0.0073 0.0333 0.0436
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0396 0.2542 0.3325
Echinococcus multilocularis chromobox protein 1 0.0148 0.0845 0.1196
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0192 0.1149 0.1149
Chlamydia trachomatis thioredoxin reductase 0.0043 0.0127 0.023
Echinococcus granulosus phosphoglycerate kinase 1 0.0547 0.3572 0.5057
Trichomonas vaginalis DNA helicase recq, putative 0.0098 0.0505 0.066
Brugia malayi hypothetical protein 0.0041 0.0113 0.0147
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0161 0.0938 0.2146
Onchocerca volvulus 0.0065 0.0279 0.0537
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0233 0.0652
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0092 0.0466 0.066
Trypanosoma brucei DNA polymerase kappa, putative 0.0189 0.1123 0.2571
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0151 0.0865 0.1668
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0058 0.0076
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0312 0.1967 0.2572

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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