Detailed information for compound 1069307

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 454.903 | Formula: C24H23ClN2O5
  • H donors: 3 H acceptors: 3 LogP: 3.84 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: ONC(=O)c1ccc(cc1)NC(=O)CCc1ccc(c(c1)OC)OCc1ccccc1Cl
  • InChi: 1S/C24H23ClN2O5/c1-31-22-14-16(6-12-21(22)32-15-18-4-2-3-5-20(18)25)7-13-23(28)26-19-10-8-17(9-11-19)24(29)27-30/h2-6,8-12,14,30H,7,13,15H2,1H3,(H,26,28)(H,27,29)
  • InChiKey: ZUURCJSEHOWMNK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens histone deacetylase 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trypanosoma cruzi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum ko:K01463 Hdac3 [EC:3.5.1.-], putative Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium parvum RPD3/HD1 histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma mansoni histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Neospora caninum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Giardia lamblia Histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium knowlesi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania major histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei gambiense histone deacetylase 1,histone deacetylase-like 1 protein, putative Get druggable targets OG5_126742 All targets in OG5_126742
Babesia bovis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium yoelii histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi Histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium hominis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium vivax histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma congolense histone deacetylase-like 1 protein, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania braziliensis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma mansoni histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Schistosoma japonicum ko:K06067 histone deacetylase 1/2, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium falciparum histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus multilocularis histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi histone deacetylase 3 (HD3) Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma cruzi histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus granulosus histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Plasmodium berghei histone deacetylase 1, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Brugia malayi histone deacetylase 1 (HD1) Get druggable targets OG5_126742 All targets in OG5_126742
Toxoplasma gondii histone deacetylase HDAC3 Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium hominis histone deacetylase Get druggable targets OG5_126742 All targets in OG5_126742
Toxoplasma gondii histone deacetylase HDAC2 Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania major histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trypanosoma brucei histone deacetylase 1 Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania infantum histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Cryptosporidium parvum histone deacetylase HDA2/Rpd3p Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania mexicana histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Theileria parva histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Leishmania donovani histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Entamoeba histolytica histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Neospora caninum hypothetical protein Get druggable targets OG5_126742 All targets in OG5_126742
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126742 All targets in OG5_126742
Candida albicans one of two distinct genes with strong similarity to S. cerevisiae RPD3 (YNL330C) SIN3 histone deacetylase complex component Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative Get druggable targets OG5_126742 All targets in OG5_126742
Trichomonas vaginalis histone deacetylase, putative Get druggable targets OG5_126742 All targets in OG5_126742
Echinococcus multilocularis histone deacetylase 3 Get druggable targets OG5_126742 All targets in OG5_126742
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni lamin 0.0027 0.0132 0.0216
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0132 0.0468
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.0446
Echinococcus multilocularis histone deacetylase 1 0.0077 0.0753 0.0753
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0397 0.0649
Loa Loa (eye worm) histone deacetylase 3 0.0077 0.0753 0.266
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0162 0.0265
Loa Loa (eye worm) hypothetical protein 0.0029 0.0154 0.0543
Echinococcus multilocularis histone deacetylase 0.0022 0.0067 0.0067
Onchocerca volvulus Alhambra homolog 0.0029 0.0154 0.0327
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.1525 0.2492
Loa Loa (eye worm) hypothetical protein 0.005 0.0411 0.1453
Brugia malayi hypothetical protein 0.0036 0.0246 0.0868
Loa Loa (eye worm) hypothetical protein 0.0153 0.1703 0.6015
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0162 0.0265
Schistosoma mansoni hypothetical protein 0.0506 0.6119 1
Brugia malayi PHD-finger family protein 0.0029 0.0154 0.0543
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0154 0.0251
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.1525 0.2492
Loa Loa (eye worm) transcription factor SMAD2 0.0243 0.2832 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0154 0.1265
Echinococcus multilocularis lamin dm0 0.0027 0.0132 0.0132
Plasmodium vivax SET domain protein, putative 0.003 0.0162 0.1391
Trypanosoma cruzi histone deacetylase 1, putative 0.0077 0.0753 1
Echinococcus multilocularis peregrin 0.0029 0.0154 0.0154
Echinococcus granulosus lamin dm0 0.0027 0.0132 0.0216
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.1525 0.2492
Loa Loa (eye worm) histone deacetylase 7A 0.0022 0.0067 0.0236
Loa Loa (eye worm) hypothetical protein 0.0027 0.0132 0.0468
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.1525 0.1525
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0154 0.1265
Onchocerca volvulus 0.003 0.0162 0.0359
Onchocerca volvulus 0.0235 0.2724 1
Brugia malayi Histone deacetylase family protein 0.0022 0.0067 0.0236
Schistosoma mansoni histone deacetylase hda2 0.0022 0.0067 0.0109
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0139 0.1525 0.1525
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.023 0.0375
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0246 0.0402
Plasmodium falciparum phd finger protein, putative 0.0029 0.0154 0.1265
Echinococcus granulosus histone deacetylase 6 0.0022 0.0067 0.0109
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.3409 1
Echinococcus multilocularis histone deacetylase 6 0.0022 0.0067 0.0067
Schistosoma mansoni histone deacetylase 0.0077 0.0753 0.1231
Trypanosoma brucei histone deacetylase 1 0.0077 0.0753 1
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0295 0.0295
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0397 0.1403
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.3409 1
Echinococcus granulosus lamin 0.0027 0.0132 0.0216
Brugia malayi Calcitonin receptor-like protein seb-1 0.0153 0.1703 0.6015
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.2368 0.8363
Echinococcus granulosus histone deacetylase 0.0022 0.0067 0.0109
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.1559 0.5
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.3409 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0162 0.0162
Schistosoma mansoni histone deacetylase 1 2 3 0.0022 0.0067 0.0109
Echinococcus multilocularis GPCR, family 2 0.0048 0.0397 0.0397
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0162 0.0265
Brugia malayi jmjC domain containing protein 0.0035 0.023 0.0811
Plasmodium vivax histone deacetylase 1, putative 0.0077 0.0753 1
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0732 0.1196
Schistosoma mansoni hypothetical protein 0.0506 0.6119 1
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0132 0.0468
Loa Loa (eye worm) histone deacetylase 0.0022 0.0067 0.0236
Brugia malayi histone deacetylase 3 (HD3) 0.0077 0.0753 0.266
Brugia malayi latrophilin 2 splice variant baaae 0.0105 0.1099 0.388
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.3409 1
Echinococcus multilocularis histone deacetylase 6 0.0022 0.0067 0.0067
Schistosoma mansoni hypothetical protein 0.0048 0.0397 0.0649
Echinococcus multilocularis histone deacetylase 3 0.0077 0.0753 0.0753
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0397 0.1403
Toxoplasma gondii histone deacetylase HDAC3 0.0077 0.0753 1
Schistosoma mansoni intermediate filament proteins 0.0027 0.0132 0.0216
Echinococcus multilocularis lamin 0.0027 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0022 0.0067 0.0236
Schistosoma mansoni hypothetical protein 0.0029 0.0154 0.0251
Echinococcus multilocularis musashi 0.0027 0.0132 0.0132
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.1559 0.5
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0162 0.0265
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0139 0.1525 0.2492
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.029 0.3409 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0243 0.2832 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.3409 1
Loa Loa (eye worm) hypothetical protein 0.0105 0.1099 0.388
Echinococcus granulosus histone deacetylase 6 0.0022 0.0067 0.0109
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0139 0.1525 0.5385
Echinococcus granulosus peregrin 0.0029 0.0154 0.0251
Schistosoma mansoni hypothetical protein 0.0048 0.0397 0.0649
Onchocerca volvulus 0.0027 0.0132 0.0247
Loa Loa (eye worm) histone deacetylase 11 0.0022 0.0067 0.0236
Echinococcus granulosus histone deacetylase 6 0.0022 0.0067 0.0109
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0154 0.0543
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.1559 0.5
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.023 0.0375
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.029 0.3409 1
Loa Loa (eye worm) histone deacetylase 1 0.0077 0.0753 0.266
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0246 0.0246
Treponema pallidum fructose-bisphosphate aldolase 0.029 0.3409 0.5
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.0974 0.1593
Echinococcus multilocularis geminin 0.0506 0.6119 0.6119
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.0974 0.0974
Brugia malayi histone deacetylase 1 (HD1) 0.0077 0.0753 0.266
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.023 0.0375
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0397 0.0649
Echinococcus granulosus GPCR family 2 0.0048 0.0397 0.0649
Brugia malayi jmjC domain containing protein 0.0095 0.0974 0.3441
Echinococcus granulosus histone deacetylase 3 0.0077 0.0753 0.1231
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.023 0.0811
Loa Loa (eye worm) hypothetical protein 0.0048 0.0397 0.1403
Loa Loa (eye worm) hypothetical protein 0.003 0.0162 0.0573
Schistosoma mansoni histone deacetylase 4 5 0.0022 0.0067 0.0109
Brugia malayi Histone deacetylase 1 0.0077 0.0753 0.266
Leishmania major histone deacetylase, putative 0.0077 0.0753 1
Schistosoma mansoni hypothetical protein 0.0048 0.0397 0.0649
Brugia malayi intermediate filament protein 0.0027 0.0132 0.0468
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0149 0.0243
Schistosoma mansoni hypothetical protein 0.0105 0.1099 0.1796
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0139 0.1525 0.2492
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.023 0.023
Schistosoma mansoni histone deacetylase hda2 0.0022 0.0067 0.0109
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0154 0.0154
Echinococcus granulosus jumonji domain containing protein 0.004 0.0295 0.0482
Giardia lamblia Histone deacetylase 0.0077 0.0753 0.1841
Brugia malayi Pre-SET motif family protein 0.003 0.0162 0.0573
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0154 0.0251
Schistosoma mansoni hypothetical protein 0.0048 0.0397 0.0649
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0162 0.0265
Echinococcus granulosus intermediate filament protein 0.0027 0.0132 0.0216
Echinococcus multilocularis histone deacetylase 7 0.0022 0.0067 0.0067
Schistosoma mansoni histone deacetylase 4 5 0.0022 0.0067 0.0109
Brugia malayi MH2 domain containing protein 0.0243 0.2832 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0397 0.0397
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0246 0.0402
Onchocerca volvulus 0.0027 0.0132 0.0247
Trypanosoma cruzi histone deacetylase 1, putative 0.0077 0.0753 1
Brugia malayi histone deacetylase 11 0.0022 0.0067 0.0236
Entamoeba histolytica histone deacetylase, putative 0.0077 0.0753 0.1604
Schistosoma mansoni lamin 0.0027 0.0132 0.0216
Giardia lamblia Fructose-bisphosphate aldolase 0.029 0.3409 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0162 0.0162
Loa Loa (eye worm) hypothetical protein 0.0077 0.0753 0.266
Echinococcus granulosus geminin 0.0506 0.6119 1
Echinococcus multilocularis histone deacetylase 6 0.0022 0.0067 0.0067
Schistosoma mansoni hypothetical protein 0.0036 0.0246 0.0402
Echinococcus granulosus histone deacetylase 1 0.0077 0.0753 0.1231
Brugia malayi Histone deacetylase family protein 0.0022 0.0067 0.0236
Plasmodium falciparum histone deacetylase 1 0.0077 0.0753 1
Trichomonas vaginalis set domain proteins, putative 0.0235 0.2724 0.7419
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.3409 1
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0538 0.1899
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0139 0.1525 0.5385
Toxoplasma gondii histone deacetylase HDAC2 0.0077 0.0753 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0397 0.1403
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.3409 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0162 0.1391
Brugia malayi Pre-SET motif family protein 0.0206 0.2368 0.8363
Brugia malayi Bromodomain containing protein 0.0029 0.0154 0.0543
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0397 0.0397
Echinococcus granulosus histone deacetylase 8 0.0022 0.0067 0.0109
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.029 0.3409 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0132 0.0468
Echinococcus granulosus histone deacetylase 7 0.0022 0.0067 0.0109
Schistosoma mansoni histone deacetylase 0.0077 0.0753 0.1231
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0154 0.1265
Leishmania major histone deacetylase, putative 0.0077 0.0753 1
Echinococcus multilocularis histone deacetylase 8 0.0022 0.0067 0.0067
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0153 0.1703 0.6015
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0153 0.1703 0.6015

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.2 uM Inhibition of HDAC1/HDAC2 from human Hela nuclear extracts using [3H]acetylated histone peptide by colorimetry ChEMBL. 19608304

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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