Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.1721 | 0.2073 |
Schistosoma mansoni | single-minded | 0.0048 | 0.0931 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.3905 | 0.6535 |
Echinococcus granulosus | RUN | 0.002 | 0.0179 | 0.0216 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0613 | 0.3081 |
Onchocerca volvulus | 0.0023 | 0.0273 | 0.0169 | |
Loa Loa (eye worm) | doublecortin family protein | 0.002 | 0.0179 | 0.03 |
Brugia malayi | hypothetical protein | 0.002 | 0.0179 | 0.024 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0051 | 0.1013 | 0.0975 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0613 | 0.0739 |
Onchocerca volvulus | 0.0026 | 0.0357 | 0.032 | |
Brugia malayi | glutathione reductase | 0.0123 | 0.2899 | 0.4819 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0078 | 0.0069 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.018 | 0.0103 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0613 | 0.097 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0273 | 0.0457 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0613 | 0.1026 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0613 | 0.1026 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0613 | 0.054 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.092 | 0.0849 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0041 | 0.0747 | 0.09 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0613 | 0.0448 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.012 | 0.0201 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0043 | 0.0787 | 0.1264 |
Onchocerca volvulus | 0.0036 | 0.0602 | 0.0764 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0049 | 0.0942 | 0.0871 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0613 | 0.3081 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0613 | 0.0688 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1042 | 0.1743 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.092 | 0.0849 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0402 | 0.0484 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0179 | 0.03 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0078 | 0.0094 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.2037 | 0.1975 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0613 | 0.0835 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.2037 | 0.2455 |
Echinococcus granulosus | tumor protein p63 | 0.0329 | 0.8298 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0082 | 0.1808 | 0.1744 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0613 | 0.1026 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0043 | 0.0787 | 0.4065 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0043 | 0.0787 | 0.2515 |
Loa Loa (eye worm) | acetyltransferase | 0.0148 | 0.3544 | 0.593 |
Plasmodium falciparum | glutathione reductase | 0.0123 | 0.2899 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.043 | 0.0518 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0043 | 0.0787 | 0.2515 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0148 | 0.0178 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0613 | 0.0688 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0043 | 0.0787 | 1 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.002 | 0.018 | 0.0216 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0203 | 0.4984 | 0.8339 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0357 | 0.043 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0273 | 0.0956 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0123 | 0.2899 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0049 | 0.0942 | 0.0871 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0273 | 0.0457 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0613 | 0.1897 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0078 | 0.0094 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.002 | 0.0179 | 0.0216 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0148 | 0.009 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0613 | 0.097 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0024 | 0.0291 | 0.0487 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0613 | 0.097 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0587 | 0.0513 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0049 | 0.0942 | 0.1135 |
Schistosoma mansoni | lipoxygenase | 0.0117 | 0.273 | 0.2673 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0037 | 0.0061 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0051 | 0.1013 | 0.1202 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0123 | 0.2899 | 0.4851 |
Onchocerca volvulus | 0.0026 | 0.0357 | 0.032 | |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0078 | 0.0069 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.0693 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0031 | 0.049 | 0.0763 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0043 | 0.0787 | 0.2515 |
Brugia malayi | hypoxia-induced factor 1 | 0.0149 | 0.3577 | 0.5961 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0587 | 0.8049 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0.0148 | 0.0176 |
Onchocerca volvulus | 0.0036 | 0.0613 | 0.0783 | |
Echinococcus granulosus | Smad4 | 0.0016 | 0.0097 | 0.0117 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.023 | 0.5709 | 0.7234 |
Brugia malayi | hypothetical protein | 0.002 | 0.0179 | 0.024 |
Echinococcus granulosus | smad | 0.0016 | 0.0097 | 0.0117 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.002 | 0.0179 | 0.0216 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0043 | 0.0787 | 0.2515 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0148 | 0.0249 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0123 | 0.2899 | 0.3625 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0078 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.2797 | 0.468 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0051 | 0.1013 | 0.1202 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0226 | 0.5584 | 0.9343 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0036 | 0.0602 | 0.0726 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0587 | 0.8049 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0016 | 0.0097 | 0.0163 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0273 | 0.0398 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0613 | 0.1026 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.043 | 0.0662 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0016 | 0.0097 | 0.0117 |
Brugia malayi | MH2 domain containing protein | 0.0241 | 0.5976 | 1 |
Mycobacterium ulcerans | putative regulatory protein | 0.0036 | 0.0602 | 0.3014 |
Brugia malayi | hypothetical protein | 0.0119 | 0.2797 | 0.4647 |
Schistosoma mansoni | smad | 0.0016 | 0.0097 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1721 | 0.2879 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0043 | 0.0787 | 0.4169 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0613 | 0.0688 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0045 | 0.0858 | 0.1274 |
Plasmodium falciparum | glutathione reductase | 0.0043 | 0.0787 | 0.2515 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.012 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.012 | 0.0201 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0613 | 0.3081 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0043 | 0.0787 | 0.2515 |
Onchocerca volvulus | 0.0029 | 0.043 | 0.0452 | |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0273 | 0.2292 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.009 | 0.2037 | 0.2455 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0016 | 0.0097 | 0.0117 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0026 | 0.0345 | 0.0415 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0179 | 0.0103 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0117 | 0.273 | 0.329 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0613 | 0.3081 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0357 | 0.0597 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.012 | 0.0201 |
Schistosoma mansoni | zinc finger protein | 0.0026 | 0.0349 | 0.0273 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0357 | 0.0539 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0072 | 0.1554 | 0.1872 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0613 | 0.054 |
Onchocerca volvulus | 0.0048 | 0.0931 | 0.1356 | |
Echinococcus multilocularis | Smad4 | 0.0016 | 0.0097 | 0.0117 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0043 | 0.0787 | 0.2515 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0313 | 0.7861 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0313 | 0.7861 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0095 | 0.0023 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0587 | 0.0707 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0613 | 0.097 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0148 | 0.0071 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0041 | 0.0747 | 0.09 |
Trypanosoma cruzi | ISWI complex protein | 0.0018 | 0.0127 | 0.0175 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0613 | 0.0688 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.002 | 0.0179 | 0.0361 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0613 | 0.0739 |
Echinococcus granulosus | single minded 2 | 0.0036 | 0.0602 | 0.0726 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0613 | 0.0688 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0016 | 0.0097 | 0.0117 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0016 | 0.0097 | 0.0163 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0357 | 0.0281 |
Trichomonas vaginalis | set domain proteins, putative | 0.0231 | 0.5718 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0018 | 0.0127 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0931 | 0.1557 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0117 | 0.273 | 0.329 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0043 | 0.0787 | 0.2515 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0043 | 0.0787 | 0.2515 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0357 | 0.043 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0357 | 0.0597 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0095 | 0.0023 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0613 | 0.0688 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0045 | 0.0858 | 0.2764 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0273 | 0.0692 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0045 | 0.0858 | 0.2764 |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.0375 | 0.1053 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0043 | 0.0787 | 0.0715 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0587 | 0.8049 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0045 | 0.0858 | 0.2764 |
Brugia malayi | Bromodomain containing protein | 0.0047 | 0.0911 | 0.1472 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0078 | 0.0094 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0043 | 0.0787 | 0.1148 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.2797 | 0.4726 |
Brugia malayi | hypothetical protein | 0.0162 | 0.3905 | 0.6514 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0024 | 0.0287 | 0.048 |
Trypanosoma brucei | trypanothione reductase | 0.0123 | 0.2899 | 1 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0357 | 0.0539 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0078 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0273 | 0.0457 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0273 | 0.0956 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0148 | 0.3544 | 0.3493 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0043 | 0.0787 | 0.2515 |
Leishmania major | trypanothione reductase | 0.0123 | 0.2899 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.002 | 0.0179 | 0.0216 |
Schistosoma mansoni | bromodomain containing protein | 0.0076 | 0.1661 | 0.1596 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0043 | 0.0787 | 0.0912 |
Treponema pallidum | NADH oxidase | 0.0043 | 0.0787 | 0.4065 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0587 | 0.0513 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0043 | 0.0787 | 0.2515 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0587 | 0.0926 |
Schistosoma mansoni | lamin | 0.0026 | 0.0357 | 0.0281 |
Loa Loa (eye worm) | glutathione reductase | 0.0123 | 0.2899 | 0.4851 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0097 | 0.0102 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.0693 | 0.2182 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0613 | 0.1026 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1721 | 0.5823 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.5808 | 0.9719 |
Onchocerca volvulus | Huntingtin homolog | 0.0119 | 0.2797 | 0.4726 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0613 | 0.1897 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0613 | 0.0835 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.2037 | 0.1975 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.012 | 0.015 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0613 | 0.0835 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0043 | 0.0787 | 0.2515 |
Brugia malayi | PHD-finger family protein | 0.0032 | 0.0509 | 0.0795 |
Brugia malayi | Pre-SET motif family protein | 0.0203 | 0.4984 | 0.8329 |
Trypanosoma cruzi | ISWI complex protein | 0.0018 | 0.0127 | 0.0175 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0043 | 0.0787 | 0.4169 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0613 | 0.1897 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.092 | 0.1487 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0043 | 0.0787 | 0.4169 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0273 | 0.0956 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0148 | 0.0249 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0027 | 0.0375 | 0.0134 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0078 | 0.1721 | 0.1656 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0043 | 0.0787 | 0.2515 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0375 | 0.1442 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0613 | 0.0448 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0273 | 0.0692 |
Plasmodium vivax | glutathione reductase, putative | 0.0123 | 0.2899 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0273 | 0.0956 |
Brugia malayi | bHLH-PAS transcription factor | 0.0036 | 0.0602 | 0.0953 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0273 | 0.2292 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0043 | 0.0787 | 0.4169 |
Schistosoma mansoni | polycystin 1-related | 0.002 | 0.0179 | 0.0103 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0613 | 0.0688 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0148 | 0.3544 | 0.427 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0281 | 0.7039 | 0.8943 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0043 | 0.0787 | 0.0949 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0273 | 0.0956 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.2797 | 0.468 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0039 | 0.0693 | 0.8529 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0043 | 0.0787 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0942 | 0.1577 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0273 | 0.0251 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0051 | 0.1013 | 0.1221 |
Echinococcus multilocularis | smad | 0.0016 | 0.0097 | 0.0117 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0048 | 0.0931 | 0.086 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0072 | 0.1554 | 0.1872 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1721 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0273 | 0.0956 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0273 | 0.0398 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0287 | 0.0211 |
Schistosoma mansoni | zinc finger protein | 0.0018 | 0.0127 | 0.005 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0234 | 0.5808 | 0.6999 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0357 | 0.043 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0234 | 0.5808 | 0.6999 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0026 | 0.0345 | 0.0269 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0043 | 0.0787 | 0.2515 |
Brugia malayi | Probable ClpP-like protease | 0.0078 | 0.1721 | 0.2835 |
Schistosoma mansoni | lamin | 0.0026 | 0.0357 | 0.0281 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0016 | 0.0097 | 0.002 |
Schistosoma mansoni | Smad4 | 0.0016 | 0.0097 | 0.002 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0613 | 0.0835 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.002 | 0.0179 | 0.0216 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1721 | 1 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.1721 | 0.5823 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.002 | 0.0179 | 0.0216 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0051 | 0.1013 | 0.1221 |
Plasmodium falciparum | thioredoxin reductase | 0.0123 | 0.2899 | 1 |
Echinococcus granulosus | zinc finger protein | 0.0026 | 0.0349 | 0.042 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0273 | 0.0956 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0095 | 0.0023 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.009 | 0.2037 | 0.1975 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1721 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0049 | 0.0942 | 0.1135 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.0097 | 0.0102 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0016 | 0.0097 | 0.0117 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0613 | 0.0835 |
Brugia malayi | Doublecortin family protein | 0.002 | 0.0179 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0613 | 0.1026 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0043 | 0.0787 | 0.2515 |
Toxoplasma gondii | thioredoxin reductase | 0.0123 | 0.2899 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0613 | 0.1897 |
Echinococcus multilocularis | tumor protein p63 | 0.0329 | 0.8298 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0613 | 0.1026 |
Schistosoma mansoni | rab6-interacting | 0.002 | 0.0179 | 0.0103 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0273 | 0.0398 |
Schistosoma mansoni | loxhd1 | 0.002 | 0.0179 | 0.0103 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0613 | 0.3081 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0179 | 0.03 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.4068 | 0.4021 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0043 | 0.0787 | 0.0949 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0043 | 0.0787 | 0.2515 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0043 | 0.0787 | 0.1148 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0148 | 0.0249 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0148 | 0.0249 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0148 | 0.0248 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0149 | 0.3577 | 0.5986 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0016 | 0.0095 | 0.0023 |
Loa Loa (eye worm) | Smad1 | 0.0016 | 0.0097 | 0.0163 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0045 | 0.0858 | 0.1033 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0357 | 0.0597 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0043 | 0.0787 | 0.2515 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.002 | 0.018 | 0.0216 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0043 | 0.0787 | 0.2515 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1721 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0026 | 0.0345 | 0.0415 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1721 | 1 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0357 | 0.043 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0097 | 0.0102 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.1721 | 0.5823 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0078 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0984 | 0.1647 |
Plasmodium falciparum | thioredoxin reductase | 0.0043 | 0.0787 | 0.2515 |
Plasmodium falciparum | LCCL domain-containing protein | 0.002 | 0.0179 | 0.0361 |
Echinococcus granulosus | lamin | 0.0026 | 0.0357 | 0.043 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0613 | 0.0835 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0281 | 0.7039 | 0.8916 |
Brugia malayi | Bromodomain containing protein | 0.0089 | 0.2013 | 0.3328 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.043 | 0.1249 |
Brugia malayi | PAS domain containing protein | 0.0048 | 0.0931 | 0.1505 |
Brugia malayi | hypothetical protein | 0.0234 | 0.5808 | 0.9717 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0043 | 0.0787 | 0.2515 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0148 | 0.0249 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0613 | 0.1026 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0148 | 0.0249 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0281 | 0.7039 | 0.8943 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0281 | 0.7039 | 0.8943 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0344 | 0.0576 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0613 | 0.0688 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.012 | 0.0201 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0613 | 0.1897 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.2037 | 0.2455 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0587 | 0.8049 |
Brugia malayi | follicle stimulating hormone receptor | 0.0226 | 0.5584 | 0.9339 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0043 | 0.0787 | 0.2515 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0043 | 0.0787 | 0.4065 |
Echinococcus granulosus | geminin | 0.0168 | 0.4068 | 0.4902 |
Brugia malayi | Smad1 | 0.0016 | 0.0097 | 0.0102 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0078 | 0.1721 | 0.1908 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0613 | 0.0688 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0043 | 0.0787 | 0.2515 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0357 | 0.043 |
Onchocerca volvulus | 0.0048 | 0.092 | 0.1337 | |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0031 | 0.049 | 0.0763 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0097 | 0.002 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.012 | 0.015 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0375 | 0.1053 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0127 | 0.005 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0148 | 0.0249 |
Onchocerca volvulus | 0.0231 | 0.5718 | 1 | |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0148 | 0.3544 | 0.5905 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0078 | 0.0094 |
Echinococcus multilocularis | zinc finger protein | 0.0026 | 0.0349 | 0.042 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0241 | 0.5976 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.082 | 0.1372 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.009 | 0.2037 | 0.2455 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0241 | 0.5976 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0273 | 0.0956 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0281 | 0.7039 | 0.8943 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0273 | 0.0251 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0097 | 0.002 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1721 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.4068 | 0.4021 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0313 | 0.7861 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0281 | 0.7039 | 0.8943 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0078 | 0.1721 | 0.5823 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.043 | 0.0355 |
Trypanosoma brucei | ISWI complex protein | 0.0018 | 0.0127 | 0.0175 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.0097 | 0.002 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0313 | 0.7861 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0124 | 0.2926 | 0.3526 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0148 | 0.0071 |
Brugia malayi | Thioredoxin reductase | 0.0123 | 0.2899 | 0.4819 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0045 | 0.0858 | 0.1274 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0587 | 0.0707 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0148 | 0.0178 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0043 | 0.0787 | 0.2515 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0124 | 0.2926 | 0.3526 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0043 | 0.0787 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.1792 | 0.2998 |
Mycobacterium tuberculosis | Probable reductase | 0.0281 | 0.7039 | 0.8943 |
Onchocerca volvulus | 0.0036 | 0.0613 | 0.0783 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0613 | 0.1897 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0027 | 0.0375 | 0.1053 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.018 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.012 | 0.0201 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.0097 | 0.0102 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0273 | 0.0692 |
Echinococcus multilocularis | RUN | 0.002 | 0.0179 | 0.0216 |
Onchocerca volvulus | 0.0036 | 0.0613 | 0.0783 | |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0931 | 0.086 |
Echinococcus multilocularis | geminin | 0.0168 | 0.4068 | 0.4902 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.009 | 0.2037 | 0.3409 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.1721 | 0.2073 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0123 | 0.2899 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.043 | 0.0355 |
Schistosoma mansoni | rab6-interacting | 0.002 | 0.0179 | 0.0103 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.002 | 0.0179 | 0.0216 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0273 | 0.2292 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.009 | 0.2037 | 0.3369 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0613 | 0.0688 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0148 | 0.0188 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0141 | 0.3366 | 0.4056 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.043 | 0.1249 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.