Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Cathepsin L-like precursor | 0.006 | 0.0544 | 0.1664 |
Entamoeba histolytica | cysteine proteinase, putative | 0.004 | 0.0299 | 0.3507 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0084 | 0.0852 | 0.3244 |
Echinococcus multilocularis | cysteine protease | 0.006 | 0.0544 | 0.0509 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.0111 | 0.0546 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0025 | 0.0111 | 0.0339 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0059 | 0.0542 | 0.1659 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0019 | 0.0037 | 0.0112 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.0333 | 0.6114 |
Plasmodium vivax | vivapain-3 | 0.0031 | 0.0184 | 0.2537 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0852 | 0.2607 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0027 | 0.0136 | 0.01 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0025 | 0.0111 | 0.0339 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0333 | 0.1266 |
Leishmania major | cathepsin L-like protease | 0.0227 | 0.2627 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.0111 | 0.0546 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0031 | 0.0184 | 0.0702 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0043 | 0.0333 | 0.0297 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0031 | 0.0184 | 0.0148 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0253 | 0.0217 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0054 | 0.0473 | 0.1447 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0227 | 0.2627 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0084 | 0.0852 | 0.3244 |
Echinococcus multilocularis | cysteine protease | 0.006 | 0.0544 | 0.0509 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0587 | 0.1795 |
Loa Loa (eye worm) | ctsf protein | 0.006 | 0.0544 | 0.1664 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.0473 | 0.0438 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0025 | 0.0111 | 0.0422 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0852 | 0.2607 |
Onchocerca volvulus | 0.0084 | 0.0852 | 0.7198 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0227 | 0.2627 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.006 | 0.0544 | 0.0509 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.0473 | 0.0438 |
Echinococcus granulosus | cathepsin l1 | 0.004 | 0.0299 | 0.0263 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0048 | 0.0146 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0043 | 0.0333 | 0.1017 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0227 | 0.2627 | 1 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0025 | 0.0111 | 0.0422 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.006 | 0.0544 | 0.1664 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0025 | 0.0111 | 0.0422 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0852 | 0.2607 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0031 | 0.0184 | 0.0702 |
Leishmania major | hypothetical protein, conserved | 0.006 | 0.0546 | 0.2079 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0192 | 0.2191 | 0.2162 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0299 | 0.0914 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0544 | 0.1664 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.0299 | 0.5494 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0043 | 0.0333 | 0.6114 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.006 | 0.0544 | 0.0509 |
Brugia malayi | Cathepsin L-like precursor | 0.006 | 0.0544 | 0.1664 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.002 | 0.0048 | 0.0146 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0057 | 0.051 | 0.1559 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Brugia malayi | Cathepsin L-like precursor | 0.006 | 0.0544 | 0.1664 |
Schistosoma mansoni | survival motor neuron protein | 0.0057 | 0.051 | 0.0475 |
Trypanosoma brucei | glucosidase, putative | 0.0043 | 0.0333 | 0.1266 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0025 | 0.0111 | 0.0546 |
Echinococcus granulosus | cathepsin l1 | 0.006 | 0.0544 | 0.0509 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0031 | 0.0184 | 0.1548 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.0333 | 0.6114 |
Mycobacterium ulcerans | hypothetical protein | 0.0084 | 0.0852 | 1 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0025 | 0.0111 | 0.0546 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0192 | 0.2191 | 0.6702 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0025 | 0.0111 | 0.0546 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.006 | 0.0544 | 0.6071 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0587 | 0.1795 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0043 | 0.0333 | 0.6114 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0027 | 0.0136 | 0.01 |
Onchocerca volvulus | 0.0025 | 0.0111 | 0.0936 | |
Echinococcus multilocularis | dnaJ subfamily B | 0.0488 | 0.5871 | 0.5856 |
Onchocerca volvulus | 0.0057 | 0.051 | 0.4305 | |
Onchocerca volvulus | 0.0064 | 0.0598 | 0.5051 | |
Onchocerca volvulus | 0.006 | 0.0544 | 0.4594 | |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0178 | 0.2022 | 0.7699 |
Loa Loa (eye worm) | cysteine protease | 0.006 | 0.0544 | 0.1664 |
Loa Loa (eye worm) | fibroinase | 0.006 | 0.0544 | 0.1664 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0084 | 0.0852 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0036 | 0.0253 | 0.0217 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0073 | 0.0706 | 0.0672 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.006 | 0.0544 | 0.0509 |
Schistosoma mansoni | intermediate filament proteins | 0.0064 | 0.0598 | 0.0563 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.006 | 0.0546 | 0.9143 |
Entamoeba histolytica | cysteine proteinase, putative | 0.006 | 0.0544 | 0.6382 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0308 | 0.0273 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0025 | 0.0111 | 0.117 |
Onchocerca volvulus | 0.0034 | 0.0229 | 0.1932 | |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.006 | 0.0544 | 0.6071 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.006 | 0.0544 | 0.0509 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0043 | 0.0333 | 0.1266 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0084 | 0.0852 | 1 |
Plasmodium vivax | unspecified product | 0.0031 | 0.0184 | 0.2537 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0031 | 0.0184 | 0.3392 |
Schistosoma mansoni | alpha-glucosidase | 0.0165 | 0.1858 | 0.1828 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0031 | 0.0184 | 0.0148 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.006 | 0.0546 | 0.2079 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0084 | 0.0852 | 1 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0025 | 0.0111 | 0.0546 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0031 | 0.0184 | 0.2165 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0192 | 0.2191 | 0.2162 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0084 | 0.0852 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.006 | 0.0544 | 0.1664 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0034 | 0.0229 | 0.07 |
Brugia malayi | cathepsin L-like precursor | 0.004 | 0.0299 | 0.0914 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.006 | 0.0544 | 0.0509 |
Onchocerca volvulus | Cathepsin F homolog | 0.006 | 0.0544 | 0.4594 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.006 | 0.0544 | 0.207 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.002 | 0.0048 | 0.0182 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.004 | 0.0299 | 0.0263 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.006 | 0.0546 | 0.2079 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0227 | 0.2627 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0084 | 0.0852 | 0.3244 |
Toxoplasma gondii | cathepsin CPL | 0.006 | 0.0544 | 0.8678 |
Echinococcus multilocularis | musashi | 0.0064 | 0.0598 | 0.0563 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0227 | 0.2627 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.006 | 0.0544 | 0.1664 |
Brugia malayi | intermediate filament protein | 0.0064 | 0.0598 | 0.1829 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0299 | 0.0914 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0186 | 0.057 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0084 | 0.0852 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.051 | 0.0475 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.006 | 0.0544 | 0.9097 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0583 | 0.1785 |
Onchocerca volvulus | 0.006 | 0.0544 | 0.4594 | |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.004 | 0.0299 | 0.0914 |
Plasmodium vivax | vivapain-2 | 0.006 | 0.0544 | 0.9203 |
Echinococcus granulosus | geminin | 0.0402 | 0.4801 | 0.4782 |
Schistosoma mansoni | hypothetical protein | 0.0402 | 0.4801 | 0.4782 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0019 | 0.0037 | 0.0112 |
Brugia malayi | Cathepsin L-like precursor | 0.004 | 0.0299 | 0.0914 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0048 | 0.0146 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.0473 | 0.0438 |
Onchocerca volvulus | 0.006 | 0.0544 | 0.4594 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.006 | 0.0546 | 0.9143 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0172 | 0.0526 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0283 | 0.0864 |
Echinococcus granulosus | lamin dm0 | 0.0064 | 0.0598 | 0.0563 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0084 | 0.0852 | 1 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.0111 | 0.0546 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.0333 | 0.6114 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0031 | 0.0184 | 0.0702 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.002 | 0.0048 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0037 | 0.0112 |
Brugia malayi | Cathepsin L-like precursor | 0.006 | 0.0544 | 0.1664 |
Brugia malayi | Cathepsin L-like precursor | 0.006 | 0.0544 | 0.1664 |
Echinococcus multilocularis | cathepsin L | 0.0031 | 0.0184 | 0.0148 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0043 | 0.0333 | 0.1017 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.006 | 0.0544 | 0.6071 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0031 | 0.0184 | 0.2165 |
Onchocerca volvulus | 0.006 | 0.0544 | 0.4594 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0227 | 0.2627 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0031 | 0.0184 | 0.2165 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0111 | 0.0339 |
Brugia malayi | AMP-binding enzyme family protein | 0.0084 | 0.0852 | 0.2607 |
Onchocerca volvulus | 0.006 | 0.0544 | 0.4594 | |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0542 | 0.1659 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0043 | 0.0333 | 0.4444 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0333 | 0.1266 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0025 | 0.0111 | 0.0422 |
Leishmania major | cathepsin L-like protease | 0.006 | 0.0544 | 0.207 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0025 | 0.0111 | 0.2037 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0043 | 0.0333 | 0.0297 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0043 | 0.0333 | 0.3902 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0025 | 0.0111 | 0.0546 |
Plasmodium vivax | vivapain-2 | 0.006 | 0.0544 | 0.9203 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.006 | 0.0544 | 0.0509 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0025 | 0.0111 | 0.0339 |
Schistosoma mansoni | alpha glucosidase | 0.0043 | 0.0333 | 0.0297 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0084 | 0.0852 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.006 | 0.0544 | 0.4594 |
Echinococcus granulosus | dnaJ subfamily B | 0.0488 | 0.5871 | 0.5856 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0059 | 0.0542 | 0.1659 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0031 | 0.0186 | 0.015 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0065 | 0.061 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0587 | 0.1795 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0084 | 0.0852 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0031 | 0.0184 | 0.2165 |
Schistosoma mansoni | lamin | 0.0064 | 0.0598 | 0.0563 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.0111 | 0.0546 |
Brugia malayi | Cathepsin L-like precursor | 0.006 | 0.0544 | 0.1664 |
Loa Loa (eye worm) | oxidoreductase | 0.0025 | 0.0111 | 0.0339 |
Echinococcus multilocularis | lamin | 0.0064 | 0.0598 | 0.0563 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0031 | 0.0184 | 0.0702 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Onchocerca volvulus | 0.0025 | 0.0111 | 0.0936 | |
Toxoplasma gondii | LsmAD domain-containing protein | 0.006 | 0.0546 | 0.8722 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0192 | 0.2191 | 0.6702 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0111 | 0.0339 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0025 | 0.0111 | 0.0074 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.006 | 0.0544 | 0.0509 |
Leishmania major | cathepsin L-like protease | 0.006 | 0.0544 | 0.207 |
Onchocerca volvulus | Cathepsin L homolog | 0.006 | 0.0544 | 0.4594 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0025 | 0.0111 | 0.0422 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0025 | 0.0111 | 0.0339 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0031 | 0.0184 | 0.2165 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0054 | 0.0473 | 0.0438 |
Onchocerca volvulus | 0.0025 | 0.0111 | 0.0936 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0111 | 0.0339 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0192 | 0.2191 | 0.2162 |
Onchocerca volvulus | 0.006 | 0.0544 | 0.4594 | |
Loa Loa (eye worm) | hypothetical protein | 0.0279 | 0.3269 | 1 |
Echinococcus granulosus | cysteine protease | 0.0031 | 0.0184 | 0.0148 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0084 | 0.0852 | 1 |
Leishmania major | cathepsin L-like protease | 0.006 | 0.0544 | 0.207 |
Echinococcus granulosus | cathepsin L | 0.0031 | 0.0184 | 0.0148 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.0333 | 0.6114 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.0473 | 0.0438 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0025 | 0.0111 | 0.0422 |
Schistosoma mansoni | alpha-glucosidase | 0.0165 | 0.1858 | 0.1828 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0063 | 0.0587 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0034 | 0.0229 | 0.07 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0084 | 0.0852 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0031 | 0.0184 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0308 | 0.0943 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.002 | 0.0048 | 0.0182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Leishmania major | cathepsin L-like protease | 0.006 | 0.0544 | 0.207 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0025 | 0.0111 | 0.13 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0034 | 0.0229 | 0.07 |
Schistosoma mansoni | lamin | 0.0064 | 0.0598 | 0.0563 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0227 | 0.2627 | 1 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0025 | 0.0111 | 0.0074 |
Plasmodium vivax | vivapain-1 | 0.0031 | 0.0184 | 0.2537 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0031 | 0.0184 | 0.0564 |
Leishmania major | cathepsin L-like protease | 0.0227 | 0.2627 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.006 | 0.0546 | 0.2079 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0031 | 0.0184 | 0.0564 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.006 | 0.0544 | 0.6382 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0136 | 0.01 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0031 | 0.0184 | 0.2165 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0587 | 0.1795 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0063 | 0.0587 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0031 | 0.0184 | 0.3392 |
Brugia malayi | hypothetical protein | 0.006 | 0.0546 | 0.1671 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0299 | 0.0914 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0025 | 0.0111 | 0.0422 |
Schistosoma mansoni | hypothetical protein | 0.0402 | 0.4801 | 0.4782 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0048 | 0.0146 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0084 | 0.0852 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.006 | 0.0544 | 0.0509 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0084 | 0.0852 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0111 | 0.0339 |
Schistosoma mansoni | hypothetical protein | 0.0488 | 0.5871 | 0.5856 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0227 | 0.2627 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0063 | 0.0587 | 0.6617 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0279 | 0.3269 | 0.3244 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0063 | 0.0587 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0036 | 0.0253 | 0.0217 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0227 | 0.2627 | 1 |
Onchocerca volvulus | 0.0064 | 0.0598 | 0.5051 | |
Onchocerca volvulus | 0.006 | 0.0544 | 0.4594 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0031 | 0.0184 | 0.0702 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0227 | 0.2627 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0227 | 0.2627 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0172 | 0.0526 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0339 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0031 | 0.0184 | 0.0148 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0054 | 0.0473 | 0.0438 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0084 | 0.0852 | 1 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0025 | 0.0111 | 0.0546 |
Brugia malayi | AMP-binding enzyme family protein | 0.0084 | 0.0852 | 0.2607 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0025 | 0.0111 | 0.2037 |
Brugia malayi | Cathepsin L-like precursor | 0.004 | 0.0299 | 0.0914 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.006 | 0.0544 | 0.6071 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0227 | 0.2627 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0063 | 0.0587 | 0.6421 |
Echinococcus granulosus | lamin | 0.0064 | 0.0598 | 0.0563 |
Brugia malayi | AMP-binding enzyme family protein | 0.0084 | 0.0852 | 0.2607 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0253 | 0.0217 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.002 | 0.0048 | 0.0146 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0025 | 0.0111 | 0.0546 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0043 | 0.0333 | 0.3902 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0025 | 0.0111 | 0.0074 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0084 | 0.0852 | 1 |
Leishmania major | cathepsin L-like protease | 0.006 | 0.0544 | 0.207 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.006 | 0.0544 | 0.9097 |
Echinococcus granulosus | intermediate filament protein | 0.0064 | 0.0598 | 0.0563 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0227 | 0.2627 | 1 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0034 | 0.0229 | 0.07 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0043 | 0.0333 | 0.6114 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0043 | 0.0333 | 0.6114 |
Brugia malayi | hypothetical protein | 0.0279 | 0.3269 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0111 | 0.0339 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0031 | 0.0186 | 0.015 |
Echinococcus multilocularis | geminin | 0.0402 | 0.4801 | 0.4782 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0048 | 0.0146 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0054 | 0.0473 | 0.0438 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0054 | 0.0473 | 0.1447 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0064 | 0.0598 | 0.1829 |
Onchocerca volvulus | 0.004 | 0.0299 | 0.2524 | |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0546 | 0.1671 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.006 | 0.0544 | 0.9097 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0025 | 0.0111 | 0.0422 |
Leishmania major | cathepsin L-like protease | 0.0227 | 0.2627 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0598 | 0.1829 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0031 | 0.0184 | 0.0702 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0059 | 0.0542 | 0.1659 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Onchocerca volvulus | 0.0025 | 0.0111 | 0.0936 | |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0279 | 0.3269 | 0.3244 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0587 | 0.1795 |
Echinococcus multilocularis | lamin dm0 | 0.0064 | 0.0598 | 0.0563 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0229 | 0.0193 |
Schistosoma mansoni | cathepsin s | 0.002 | 0.0048 | 0.0011 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0025 | 0.0111 | 0.0422 |
Entamoeba histolytica | cysteine protease, putative | 0.0031 | 0.0184 | 0.2165 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0227 | 0.2627 | 1 |
Onchocerca volvulus | 0.0111 | 0.1184 | 1 | |
Brugia malayi | Latrophilin receptor protein 2 | 0.0019 | 0.0037 | 0.0112 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.004 | 0.0299 | 0.5494 |
Loa Loa (eye worm) | intermediate filament protein | 0.0064 | 0.0598 | 0.1829 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0043 | 0.0333 | 0.6114 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.006 | 0.0546 | 0.9243 |
Entamoeba histolytica | cysteine protease, putative | 0.006 | 0.0544 | 0.6382 |
Trypanosoma cruzi | cysteine protease, putative | 0.0031 | 0.0184 | 0.0702 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0064 | 0.0598 | 0.1829 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0041 | 0.0308 | 0.0943 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0227 | 0.2627 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.006 | 0.0544 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.006 | 0.0544 | 0.207 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0207 | 0.2382 | 0.9067 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | < 30 % | Inhibition of ROS1 at 20 uM by HotSpot assay | ChEMBL. | 19700314 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.