Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0034 | 0.0315 | 0.0477 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0517 | 0.1294 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0009 | 0.0006 | 0.001 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.003 | 0.0263 | 0.0291 |
Brugia malayi | hypothetical protein | 0.0258 | 0.3144 | 0.7864 |
Echinococcus multilocularis | muscleblind protein | 0.0325 | 0.3998 | 0.3949 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0043 | 0.043 | 0.086 |
Onchocerca volvulus | 0.0034 | 0.0315 | 0.0262 | |
Onchocerca volvulus | 0.0259 | 0.3165 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0325 | 0.3998 | 1 |
Echinococcus granulosus | geminin | 0.0167 | 0.2001 | 0.3913 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.043 | 0.0481 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.003 | 0.0263 | 0.0294 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0714 | 0.891 | 1 |
Onchocerca volvulus | 0.0043 | 0.043 | 0.0655 | |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0056 | 0.0598 | 0.1496 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0154 | 0.1839 | 0.5808 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0404 | 0.4989 | 0.4948 |
Schistosoma mansoni | cpg binding protein | 0.006 | 0.0643 | 0.1288 |
Trichomonas vaginalis | esterase, putative | 0.0043 | 0.043 | 0.1355 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0121 | 0.1418 | 0.2842 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0154 | 0.1839 | 0.5808 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0009 | 0.0006 | 0.0005 |
Schistosoma mansoni | cpg binding protein | 0.006 | 0.0643 | 0.1288 |
Echinococcus multilocularis | cpg binding protein | 0.006 | 0.0643 | 0.0567 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0025 | 0.02 | 0.0224 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.0315 | 0.0787 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.043 | 0.1075 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0043 | 0.043 | 0.0481 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0024 | 0.0189 | 0.0209 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.003 | 0.0263 | 0.0291 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0108 | 0.1257 | 1 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0028 | 0.0238 | 0.0266 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.005 | 0.0155 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0013 | 0.005 | 0.0155 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0028 | 0.0238 | 0.0595 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0274 | 0.3348 | 0.3757 |
Brugia malayi | AMP-binding enzyme family protein | 0.0009 | 0.0003 | 0.0008 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0016 | 0.009 | 0.002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.005 | 0.0155 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0021 | 0.0157 | 0.0175 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.1088 | 0.1016 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0154 | 0.1839 | 0.5808 |
Loa Loa (eye worm) | hypothetical protein | 0.0258 | 0.3144 | 0.7864 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.009 | 0.0226 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0057 | 0.0602 | 0.1507 |
Brugia malayi | beta-lactamase family protein | 0.0043 | 0.043 | 0.1075 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.043 | 0.0481 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.1088 | 0.218 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0044 | 0.0448 | 0.0502 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0044 | 0.0448 | 0.0496 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.043 | 0.1355 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.009 | 0.0226 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0029 | 0.0251 | 0.0281 |
Schistosoma mansoni | smad | 0.0016 | 0.009 | 0.0179 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0053 | 0.0563 | 0.1111 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0019 | 0.0124 | 0.0044 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.2001 | 0.401 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0154 | 0.1839 | 0.5808 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0043 | 0.043 | 0.0481 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0019 | 0.0131 | 0.0455 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0043 | 0.043 | 0.0481 |
Mycobacterium ulcerans | thioesterase | 0.0025 | 0.02 | 0.0221 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0043 | 0.043 | 0.0479 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.043 | 0.0481 |
Leishmania major | hypothetical protein, conserved | 0.0043 | 0.043 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0325 | 0.3998 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.005 | 0.0155 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.003 | 0.0263 | 0.0657 |
Brugia malayi | MH2 domain containing protein | 0.0016 | 0.009 | 0.0226 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0552 | 0.1105 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0043 | 0.043 | 0.0711 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.043 | 0.1075 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.043 | 0.1075 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.043 | 0.1075 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0235 | 0.2858 | 0.7148 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0031 | 0.0286 | 0.0317 |
Echinococcus multilocularis | smad | 0.0016 | 0.009 | 0.001 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0315 | 0.2013 |
Schistosoma mansoni | Smad4 | 0.0016 | 0.009 | 0.0179 |
Schistosoma mansoni | hypothetical protein | 0.0404 | 0.4989 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0325 | 0.3998 | 0.3949 |
Echinococcus granulosus | dnaJ subfamily B | 0.0404 | 0.4989 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0325 | 0.3998 | 0.7981 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0016 | 0.009 | 0.002 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0009 | 0.0001 | 0.0002 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.009 | 0.0179 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0009 | 0.0006 | 0.0003 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0024 | 0.0189 | 0.0206 |
Loa Loa (eye worm) | acyl carrier protein | 0.0014 | 0.006 | 0.0151 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0044 | 0.0448 | 0.0499 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0154 | 0.1839 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0013 | 0.005 | 0.0155 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0228 | 0.2769 | 0.6927 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0025 | 0.02 | 0.0218 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0031 | 0.0286 | 0.1768 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0013 | 0.005 | 0.0155 |
Brugia malayi | MH1 domain containing protein | 0.0016 | 0.009 | 0.0226 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0043 | 0.043 | 0.1355 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.005 | 0.0155 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0043 | 0.043 | 0.086 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.005 | 0.0155 |
Loa Loa (eye worm) | fatty acid synthase | 0.0029 | 0.0258 | 0.0644 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0235 | 0.2858 | 0.7148 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.003 | 0.0263 | 0.0294 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0284 | 0.0414 |
Brugia malayi | beta-lactamase | 0.0043 | 0.043 | 0.1075 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0053 | 0.0552 | 0.1381 |
Brugia malayi | MH2 domain containing protein | 0.0235 | 0.2858 | 0.7148 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0154 | 0.1839 | 0.5808 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0315 | 0.0787 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0034 | 0.0315 | 0.0236 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0015 | 0.0081 | 0.016 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0019 | 0.0124 | 0.0089 |
Trichomonas vaginalis | helicase, putative | 0.0013 | 0.005 | 0.0155 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.043 | 0.1355 |
Loa Loa (eye worm) | beta-lactamase | 0.0043 | 0.043 | 0.1075 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0031 | 0.0286 | 0.0317 |
Echinococcus multilocularis | geminin | 0.0167 | 0.2001 | 0.1936 |
Brugia malayi | beta-lactamase family protein | 0.0043 | 0.043 | 0.1075 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0095 | 0.1088 | 0.2722 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.1088 | 0.218 |
Mycobacterium ulcerans | beta-lactamase | 0.0043 | 0.043 | 0.0479 |
Brugia malayi | Smad1 | 0.0016 | 0.009 | 0.0226 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.043 | 0.1355 |
Onchocerca volvulus | 0.0052 | 0.054 | 0.1031 | |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0043 | 0.043 | 0.1075 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.005 | 0.0155 |
Loa Loa (eye worm) | histone methyltransferase | 0.0019 | 0.0124 | 0.0311 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0016 | 0.009 | 0.001 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0017 | 0.0101 | 0.0112 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.009 | 0.0179 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0714 | 0.891 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0043 | 0.043 | 0.0479 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0315 | 0.0629 |
Mycobacterium leprae | Probable lipase LipE | 0.0043 | 0.043 | 0.0476 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.1088 | 0.2053 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0013 | 0.005 | 0.0155 |
Schistosoma mansoni | survival motor neuron protein | 0.0053 | 0.0552 | 0.1105 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0021 | 0.0155 | 0.0656 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.1088 | 0.1016 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0031 | 0.0286 | 0.0315 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0154 | 0.1839 | 0.5 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0009 | 0.0003 | 0.0003 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.003 | 0.0263 | 0.0288 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0016 | 0.009 | 0.0226 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0154 | 0.1839 | 0.5808 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0013 | 0.005 | 0.0155 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0034 | 0.0315 | 0.0629 |
Mycobacterium ulcerans | thioesterase TesA | 0.0025 | 0.02 | 0.0221 |
Mycobacterium ulcerans | polyketide synthase | 0.003 | 0.0263 | 0.0291 |
Brugia malayi | Pre-SET motif family protein | 0.0228 | 0.2769 | 0.6927 |
Brugia malayi | CXXC zinc finger family protein | 0.0057 | 0.0602 | 0.1507 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0154 | 0.1839 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0095 | 0.1088 | 0.2722 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.0315 | 0.0236 |
Loa Loa (eye worm) | Smad1 | 0.0016 | 0.009 | 0.0226 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.2001 | 0.401 |
Toxoplasma gondii | ABC1 family protein | 0.0043 | 0.043 | 0.2988 |
Trichomonas vaginalis | set domain proteins, putative | 0.0259 | 0.3165 | 1 |
Echinococcus granulosus | Smad4 | 0.0016 | 0.009 | 0.002 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0013 | 0.005 | 0.0155 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0031 | 0.0286 | 0.0315 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0016 | 0.009 | 0.0226 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.043 | 0.1075 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.0238 | 0.0595 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0043 | 0.043 | 0.0352 |
Mycobacterium ulcerans | polyketide synthase | 0.0031 | 0.0286 | 0.0317 |
Schistosoma mansoni | cpg binding protein | 0.0057 | 0.0602 | 0.1206 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0031 | 0.0286 | 0.032 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.002 | 0.0136 | 0.0146 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0043 | 0.043 | 0.1075 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0031 | 0.0286 | 0.032 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0031 | 0.0286 | 0.032 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0043 | 0.043 | 0.0481 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.043 | 0.5 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0154 | 0.1839 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0013 | 0.005 | 0.0155 |
Schistosoma mansoni | smad1 5 8 and | 0.0016 | 0.009 | 0.0179 |
Mycobacterium ulcerans | lipase LipD | 0.0043 | 0.043 | 0.0479 |
Onchocerca volvulus | 0.0043 | 0.043 | 0.0655 | |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.001 | 0.0017 | 0.0018 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.1088 | 0.2053 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.003 | 0.0263 | 0.0288 |
Echinococcus granulosus | cpg binding protein | 0.006 | 0.0643 | 0.1146 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.005 | 0.0155 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0016 | 0.009 | 0.001 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.005 | 0.0155 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0154 | 0.1839 | 0.5808 |
Echinococcus multilocularis | Smad4 | 0.0016 | 0.009 | 0.001 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0016 | 0.009 | 0.0179 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.003 | 0.0263 | 0.0294 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.002 | 0.0136 | 0.0149 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0043 | 0.043 | 0.0481 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0024 | 0.0189 | 0.0209 |
Brugia malayi | Muscleblind-like protein | 0.0325 | 0.3998 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0315 | 0.0629 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0013 | 0.005 | 0.0155 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.002 | 0.0136 | 0.0149 |
Onchocerca volvulus | 0.0057 | 0.0602 | 0.1245 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0013 | 0.005 | 0.0155 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.003 | 0.0263 | 0.0291 |
Mycobacterium leprae | conserved hypothetical protein | 0.0043 | 0.043 | 0.0476 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0029 | 0.0251 | 0.0281 |
Onchocerca volvulus | 0.0043 | 0.043 | 0.0655 | |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0018 | 0.0121 | 0.0304 |
Mycobacterium ulcerans | hypothetical protein | 0.0043 | 0.043 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.043 | 0.1075 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0043 | 0.043 | 0.0481 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.043 | 0.5 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0012 | 0.004 | 0.0043 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0043 | 0.043 | 0.0481 |
Plasmodium vivax | hypothetical protein, conserved | 0.0043 | 0.043 | 1 |
Onchocerca volvulus | 0.0053 | 0.0552 | 0.1073 | |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0258 | 0.3144 | 0.6242 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0044 | 0.0448 | 0.0502 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0024 | 0.0194 | 0.0217 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0258 | 0.3144 | 0.3088 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0098 | 0.0245 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0043 | 0.043 | 0.5 |
Echinococcus granulosus | smad | 0.0016 | 0.009 | 0.002 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0315 | 0.0629 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0043 | 0.043 | 0.1355 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0714 | 0.891 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.1088 | 0.218 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0031 | 0.0286 | 0.0315 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.003 | 0.0263 | 0.0291 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0154 | 0.1839 | 0.5808 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.