Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0033 | 0.026 | 0.0767 | |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0153 | 0.1484 | 0.627 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0123 | 0.1183 | 0.1183 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0025 | 0.0181 | 0.0753 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.0009 | 0.002 | 0.002 |
Echinococcus multilocularis | low density lipoprotein receptor (ldl) | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.002 | 0.0055 |
Brugia malayi | Smad1 | 0.0024 | 0.0177 | 0.0496 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0021 | 0.0142 | 0.2572 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.006 | 0.0542 | 0.2284 |
Loa Loa (eye worm) | nuclear factor I | 0.0013 | 0.0066 | 0.0185 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0023 | 0.016 | 0.016 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0123 | 0.1183 | 0.1183 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0021 | 0.0142 | 0.2572 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.002 | 0.0055 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0021 | 0.0142 | 0.2572 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0086 | 0.0806 | 0.226 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.031 | 0.1302 |
Brugia malayi | TAR-binding protein | 0.0056 | 0.0504 | 0.1413 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0021 | 0.0142 | 1 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0009 | 0.002 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0238 | 0.0667 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0023 | 0.0159 | 0.0159 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.005 | 0.044 | 0.1851 |
Onchocerca volvulus | 0.0176 | 0.1717 | 0.506 | |
Schistosoma mansoni | hypothetical protein | 0.0007 | 0.0001 | 0.0001 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0025 | 0.0181 | 0.0604 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.018 | 0.1197 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0007 | 0.0003 | 0.0008 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0023 | 0.0159 | 0.0159 |
Brugia malayi | Low-density lipoprotein receptor-related protein, putative | 0.0007 | 0.0001 | 0.0003 |
Onchocerca volvulus | 0.0007 | 0.0001 | 0.0003 | |
Brugia malayi | glutathione reductase | 0.006 | 0.0542 | 0.152 |
Loa Loa (eye worm) | low-density lipoprotein receptor domain class A containing protein | 0.0007 | 0.0001 | 0.0003 |
Onchocerca volvulus | 0.0011 | 0.0045 | 0.0134 | |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0016 | 0.0089 | 0.0294 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.018 | 0.0505 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0021 | 0.0142 | 0.2572 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0023 | 0.016 | 0.016 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0023 | 0.0159 | 0.0159 |
Schistosoma mansoni | ap endonuclease | 0.0016 | 0.0089 | 0.0089 |
Leishmania major | trypanothione reductase | 0.006 | 0.0542 | 0.1831 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0117 | 0.0327 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.0003 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.031 | 0.087 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0033 | 0.026 | 0.026 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.0009 | 0.002 | 0.0057 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0009 | 0.002 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.002 | 0.0055 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0009 | 0.002 | 0.0057 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0016 | 0.0089 | 0.5732 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0226 | 0.0635 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0009 | 0.0009 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0016 | 0.0089 | 0.0572 |
Echinococcus granulosus | nibrin | 0.0009 | 0.002 | 0.002 |
Brugia malayi | topoisomerase | 0.0009 | 0.002 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0117 | 0.7958 |
Echinococcus granulosus | expressed conserved protein | 0.0081 | 0.0753 | 0.0753 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.143 | 0.4009 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0137 | 0.1328 | 0.561 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0226 | 0.0635 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0027 | 0.0075 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0011 | 0.0045 | 0.0248 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.031 | 0.087 |
Brugia malayi | MH2 domain containing protein | 0.0024 | 0.0177 | 0.0496 |
Brugia malayi | basement membrane proteoglycan precursor | 0.0007 | 0.0001 | 0.0003 |
Schistosoma mansoni | Smad4 | 0.0024 | 0.0177 | 0.0177 |
Brugia malayi | MH1 domain containing protein | 0.0024 | 0.0177 | 0.0496 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.006 | 0.0542 | 0.0542 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0025 | 0.0181 | 0.0181 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.031 | 0.2027 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.031 | 0.087 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.031 | 0.1302 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0003 | 0.0008 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.018 | 0.1169 |
Schistosoma mansoni | smad | 0.0011 | 0.004 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0003 | 0.0008 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0009 | 0.002 | 0.0057 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0009 | 0.002 | 0.0312 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0007 | 0.0003 | 0.0003 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.031 | 0.1044 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0016 | 0.0089 | 0.0506 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0034 | 0.0272 | 0.0763 |
Toxoplasma gondii | ATPase, AAA family protein | 0.0009 | 0.002 | 0.0312 |
Schistosoma mansoni | Smad4 | 0.0011 | 0.004 | 0.004 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0009 | 0.002 | 0.0098 |
Brugia malayi | PAS domain containing protein | 0.0044 | 0.0376 | 0.1055 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0136 | 0.1314 | 0.3683 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0003 | 0.0008 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.031 | 0.2027 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.0009 | 0.002 | 0.0055 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.018 | 0.0602 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.031 | 0.087 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0011 | 0.0045 | 0.0248 |
Echinococcus multilocularis | muscleblind protein | 0.0103 | 0.0978 | 0.0978 |
Echinococcus multilocularis | musashi | 0.0063 | 0.0569 | 0.0569 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0007 | 0.0001 | 0.0003 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0016 | 0.0089 | 0.1607 |
Trichomonas vaginalis | set domain proteins, putative | 0.0176 | 0.1717 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0021 | 0.0142 | 0.0142 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.031 | 0.5701 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0056 | 0.0504 | 0.1413 |
Echinococcus multilocularis | Low density lipoprotein receptor, class A, cysteine rich | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0117 | 0.0327 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0011 | 0.004 | 0.004 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0218 | 0.0612 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.039 | 0.1094 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0007 | 0.0001 | 0.0001 |
Onchocerca volvulus | 0.0007 | 0.0001 | 0.0003 | |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0806 | 0.226 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0153 | 0.1484 | 0.627 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | single-minded | 0.0044 | 0.0376 | 0.0376 |
Brugia malayi | isocitrate dehydrogenase | 0.0025 | 0.0181 | 0.0507 |
Leishmania major | protein kinase, putative | 0.0011 | 0.0045 | 0.0144 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0011 | 0.0045 | 0.0144 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0009 | 0.002 | 0.0057 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0023 | 0.0159 | 0.0446 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.018 | 0.0602 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0142 | 0.0471 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.018 | 0.0505 |
Schistosoma mansoni | smad1 5 8 and | 0.0024 | 0.0177 | 0.0177 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.031 | 0.1302 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.0009 | 0.002 | 0.0113 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0159 | 0.0159 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.031 | 0.1302 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0021 | 0.0142 | 0.0471 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0142 | 0.0471 |
Onchocerca volvulus | 0.0007 | 0.0001 | 0.0003 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0056 | 0.0504 | 0.0504 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0086 | 0.0806 | 0.0806 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.005 | 0.044 | 0.1484 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0159 | 0.0159 |
Echinococcus granulosus | low density lipoprotein receptor ldl | 0.0007 | 0.0001 | 0.0001 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0142 | 0.0471 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0106 | 0.0439 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.031 | 0.1302 |
Schistosoma mansoni | tar DNA-binding protein | 0.0056 | 0.0504 | 0.0504 |
Loa Loa (eye worm) | TAR-binding protein | 0.0056 | 0.0504 | 0.1413 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.018 | 0.0505 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0003 | 0.0008 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0007 | 0.0003 | 0.0008 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0021 | 0.0142 | 0.0915 |
Schistosoma mansoni | topbp1 | 0.0009 | 0.002 | 0.002 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.031 | 0.1044 |
Schistosoma mansoni | survival motor neuron protein | 0.0073 | 0.0671 | 0.0671 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.003 | 0.0238 | 0.0238 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.031 | 0.2027 |
Entamoeba histolytica | hypothetical protein | 0.0052 | 0.046 | 0.5696 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.018 | 0.2208 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0021 | 0.0142 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0405 | 0.4051 | 0.4051 |
Echinococcus granulosus | dnaJ subfamily B | 0.0405 | 0.4051 | 0.4051 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.031 | 0.1302 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0154 | 0.1501 | 0.4206 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.005 | 0.044 | 0.1234 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0011 | 0.004 | 0.0112 |
Brugia malayi | MH2 domain containing protein | 0.0024 | 0.0177 | 0.0496 |
Echinococcus granulosus | replication factor c subunit 1 | 0.0009 | 0.002 | 0.002 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.0009 | 0.002 | 0.0055 |
Brugia malayi | Pre-SET motif family protein | 0.0023 | 0.016 | 0.0448 |
Brugia malayi | hypothetical protein | 0.0052 | 0.046 | 0.1291 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0016 | 0.0089 | 0.0294 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0042 | 0.0355 | 0.0355 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0021 | 0.0142 | 1 |
Onchocerca volvulus | 0.0007 | 0.0003 | 0.0008 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0023 | 0.016 | 0.016 |
Echinococcus multilocularis | low density lipoprotein receptor protein | 0.0007 | 0.0001 | 0.0001 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0021 | 0.0142 | 0.0471 |
Echinococcus multilocularis | Low density lipoprotein receptor, class A, cysteine rich | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0011 | 0.0045 | 0.0127 |
Echinococcus granulosus | low density lipoprotein receptor protein | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0042 | 0.0355 | 0.0355 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0025 | 0.0181 | 0.0181 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0142 | 0.0471 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0009 | 0.0009 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0016 | 0.0089 | 0.0251 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0024 | 0.0177 | 0.0177 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0025 | 0.0181 | 0.0181 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0009 | 0.002 | 0.0057 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0011 | 0.0045 | 0.0045 |
Plasmodium falciparum | glutathione reductase | 0.006 | 0.0542 | 1 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0011 | 0.0045 | 0.0144 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0021 | 0.0142 | 0.0471 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0025 | 0.0181 | 0.3298 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0021 | 0.0142 | 0.0471 |
Schistosoma mansoni | intermediate filament proteins | 0.0063 | 0.0569 | 0.0569 |
Onchocerca volvulus | 0.0073 | 0.0677 | 0.1996 | |
Entamoeba histolytica | hypothetical protein | 0.0052 | 0.046 | 0.5696 |
Schistosoma mansoni | hypothetical protein | 0.0007 | 0.0001 | 0.0001 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0011 | 0.0045 | 0.2109 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0011 | 0.004 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.002 | 0.0055 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.0354 | 0.1191 |
Schistosoma mansoni | tar DNA-binding protein | 0.0056 | 0.0504 | 0.0504 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0558 | 0.1563 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.018 | 0.1169 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Plasmodium falciparum | thioredoxin reductase | 0.006 | 0.0542 | 1 |
Echinococcus granulosus | geminin | 0.0301 | 0.2997 | 0.2997 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0354 | 0.1191 |
Brugia malayi | Isocitrate dehydrogenase | 0.0025 | 0.0181 | 0.0507 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0159 | 0.0159 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0011 | 0.004 | 0.004 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0159 | 0.0159 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0007 | 0.0003 | 0.0003 |
Onchocerca volvulus | 0.0028 | 0.0218 | 0.0644 | |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0021 | 0.0142 | 0.0915 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0011 | 0.004 | 0.0117 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.018 | 0.1169 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0117 | 0.0327 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.018 | 0.0505 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0137 | 0.1328 | 0.8946 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0009 | 0.0009 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0045 | 0.0248 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0042 | 0.0355 | 0.2324 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0011 | 0.0045 | 0.0248 |
Brugia malayi | hypothetical protein | 0.0147 | 0.143 | 0.4009 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.018 | 0.1169 |
Echinococcus multilocularis | protein patched | 0.0037 | 0.0305 | 0.0305 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0978 | 0.2742 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0011 | 0.004 | 0.004 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0357 | 0.3567 | 0.3567 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0052 | 0.046 | 0.046 |
Loa Loa (eye worm) | hypothetical protein | 0.0357 | 0.3567 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.031 | 0.1795 |
Onchocerca volvulus | 0.0037 | 0.031 | 0.0915 | |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0218 | 0.0218 |
Mycobacterium tuberculosis | Probable reductase | 0.0137 | 0.1328 | 0.561 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0009 | 0.002 | 0.0098 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0045 | 0.0248 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0071 | 0.0657 | 0.184 |
Loa Loa (eye worm) | Smad1 | 0.0024 | 0.0177 | 0.0496 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0021 | 0.0142 | 0.0142 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.0009 | 0.002 | 0.002 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0671 | 0.0671 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0063 | 0.0569 | 0.1596 |
Brugia malayi | hypoxia-induced factor 1 | 0.0136 | 0.1314 | 0.3683 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0235 | 0.0235 |
Onchocerca volvulus | 0.0007 | 0.0001 | 0.0003 | |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0156 | 0.152 | 0.6422 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0235 | 0.0235 |
Echinococcus granulosus | Smad4 | 0.0024 | 0.0177 | 0.0177 |
Brugia malayi | CHE-14 protein | 0.0037 | 0.0305 | 0.0856 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0009 | 0.002 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.034 | 0.3393 | 0.9511 |
Echinococcus granulosus | smad | 0.0024 | 0.0177 | 0.0177 |
Brugia malayi | MH2 domain containing protein | 0.0357 | 0.3566 | 0.9995 |
Schistosoma mansoni | Smad4 | 0.0011 | 0.004 | 0.004 |
Onchocerca volvulus | 0.034 | 0.3393 | 1 | |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0011 | 0.0045 | 0.0248 |
Entamoeba histolytica | hypothetical protein | 0.0052 | 0.046 | 0.5696 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0677 | 0.1898 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0137 | 0.1328 | 0.561 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0011 | 0.004 | 0.004 |
Onchocerca volvulus | Arrow homolog | 0.0007 | 0.0001 | 0.0003 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0103 | 0.0978 | 0.0978 |
Echinococcus multilocularis | tar DNA binding protein | 0.0056 | 0.0504 | 0.0504 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0021 | 0.0142 | 0.081 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0405 | 0.4051 | 0.4051 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0011 | 0.0045 | 0.0144 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.005 | 0.044 | 0.044 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.0354 | 0.1191 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0117 | 0.0751 |
Onchocerca volvulus | 0.0073 | 0.0671 | 0.1978 | |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0016 | 0.0089 | 0.0294 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0292 | 0.0292 |
Echinococcus multilocularis | nibrin | 0.0009 | 0.002 | 0.002 |
Plasmodium vivax | thioredoxin reductase, putative | 0.006 | 0.0542 | 1 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0016 | 0.0089 | 0.0367 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0011 | 0.0045 | 0.0045 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.031 | 0.1302 |
Brugia malayi | AMP-binding enzyme family protein | 0.0007 | 0.0003 | 0.0008 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.003 | 0.0238 | 0.0238 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0021 | 0.0142 | 0.0471 |
Treponema pallidum | NADH oxidase | 0.0021 | 0.0142 | 1 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.0007 | 0.0001 | 0.0001 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0021 | 0.0142 | 0.0588 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0007 | 0.0001 | 0.0003 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0025 | 0.0181 | 0.0181 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.018 | 0.0602 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0016 | 0.0089 | 0.0251 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0021 | 0.0142 | 0.2572 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0025 | 0.0181 | 0.0604 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0117 | 0.2111 |
Onchocerca volvulus | 0.0007 | 0.0003 | 0.0008 | |
Toxoplasma gondii | exonuclease III APE | 0.0016 | 0.0089 | 0.1607 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0016 | 0.0089 | 0.0089 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0447 | 0.1506 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0016 | 0.0089 | 0.0294 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0071 | 0.0657 | 0.184 |
Schistosoma mansoni | tar DNA-binding protein | 0.0056 | 0.0504 | 0.0504 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0023 | 0.016 | 0.016 |
Loa Loa (eye worm) | calcium binding EGF domain-containing protein | 0.0007 | 0.0001 | 0.0003 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.0009 | 0.002 | 0.0111 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0049 | 0.0426 | 0.1195 |
Brugia malayi | enteropeptidase precursor | 0.0007 | 0.0001 | 0.0003 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0292 | 0.0292 |
Plasmodium falciparum | thioredoxin reductase | 0.0021 | 0.0142 | 0.2572 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0037 | 0.0305 | 0.1766 |
Echinococcus multilocularis | low density lipoprotein receptor (ldl) | 0.0007 | 0.0001 | 0.0001 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0297 | 0.295 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0024 | 0.0177 | 0.0177 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0416 | 0.7663 |
Onchocerca volvulus | 0.0023 | 0.016 | 0.0471 | |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.031 | 0.1302 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0142 | 0.0471 |
Onchocerca volvulus | 0.0037 | 0.031 | 0.0915 | |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0239 | 0.2365 | 1 |
Brugia malayi | bHLH-PAS transcription factor | 0.0033 | 0.026 | 0.0729 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0087 | 0.082 | 0.082 |
Echinococcus granulosus | lamin dm0 | 0.0063 | 0.0569 | 0.0569 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0052 | 0.046 | 0.046 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.005 | 0.044 | 0.2882 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.018 | 0.1169 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.031 | 0.2076 |
Onchocerca volvulus | 0.0011 | 0.0037 | 0.011 | |
Brugia malayi | hypothetical protein | 0.034 | 0.3393 | 0.9511 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0117 | 0.0482 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.031 | 0.1044 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.031 | 0.2076 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0137 | 0.1328 | 0.561 |
Brugia malayi | MH1 domain containing protein | 0.0024 | 0.0177 | 0.0496 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.031 | 0.2027 |
Onchocerca volvulus | 0.0009 | 0.002 | 0.0058 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0009 | 0.002 | 0.0098 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0037 | 0.0305 | 0.0305 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0086 | 0.0806 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.006 | 0.0542 | 0.152 |
Entamoeba histolytica | hypothetical protein | 0.0009 | 0.002 | 0.0209 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0117 | 0.2111 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0426 | 0.1195 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.031 | 0.087 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.006 | 0.0542 | 0.1831 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.031 | 0.1302 |
Echinococcus granulosus | basement membrane specific heparan sulfate | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | glutathione reductase | 0.006 | 0.0542 | 0.152 |
Echinococcus granulosus | tar DNA binding protein | 0.0056 | 0.0504 | 0.0504 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0023 | 0.016 | 0.2911 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.031 | 0.031 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0026 | 0.0072 |
Schistosoma mansoni | topbp1 | 0.0009 | 0.002 | 0.002 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0007 | 0.0001 | 0.0003 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0015 | 0.0085 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.031 | 0.087 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0007 | 0.0003 | 0.0008 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0073 | 0.0671 | 0.1881 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0047 | 0.0406 | 0.1137 |
Echinococcus granulosus | low density lipoprotein receptor ldl | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0052 | 0.046 | 0.046 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0559 | 0.5623 | 0.5623 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0011 | 0.0045 | 0.0144 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.031 | 0.087 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.0657 | 0.184 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.046 | 0.046 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0024 | 0.0177 | 0.0177 |
Echinococcus multilocularis | GPCR, family 2 | 0.0023 | 0.0159 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Echinococcus granulosus | lamin | 0.0063 | 0.0569 | 0.0569 |
Schistosoma mansoni | tar DNA-binding protein | 0.0056 | 0.0504 | 0.0504 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0153 | 0.1484 | 0.627 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0011 | 0.0045 | 0.0248 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0021 | 0.0142 | 0.0471 |
Echinococcus granulosus | muscleblind protein | 0.0103 | 0.0978 | 0.0978 |
Echinococcus granulosus | Low density lipoprotein receptor class A cysteine rich | 0.0007 | 0.0001 | 0.0001 |
Schistosoma mansoni | patched 1 | 0.0037 | 0.0305 | 0.0305 |
Brugia malayi | CUB domain containing protein | 0.0007 | 0.0001 | 0.0003 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0007 | 0.0003 | 0.0003 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.031 | 0.1795 |
Onchocerca volvulus | 0.0007 | 0.0003 | 0.0008 | |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0142 | 0.0471 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0056 | 0.0504 | 0.1413 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0042 | 0.0355 | 0.0355 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0042 | 0.0355 | 0.1493 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0063 | 0.0569 | 0.1596 |
Entamoeba histolytica | hypothetical protein | 0.0052 | 0.046 | 0.5696 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0021 | 0.0142 | 0.0471 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.031 | 0.5701 |
Echinococcus granulosus | single minded 2 | 0.0033 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0073 | 0.0677 | 0.0677 |
Loa Loa (eye worm) | oxidoreductase | 0.0007 | 0.0003 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.031 | 0.087 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.2997 | 0.2997 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0007 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.004 | 0.0112 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0042 | 0.0355 | 0.6535 |
Mycobacterium ulcerans | putative regulatory protein | 0.0033 | 0.026 | 0.1696 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0066 | 0.0185 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.0486 | 0.8947 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0292 | 0.0292 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0016 | 0.0089 | 0.108 |
Brugia malayi | hypothetical protein | 0.0009 | 0.002 | 0.0055 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0106 | 0.0439 |
Schistosoma mansoni | low-density lipoprotein receptor (ldl) | 0.0007 | 0.0001 | 0.0001 |
Brugia malayi | Muscleblind-like protein | 0.0103 | 0.0978 | 0.2742 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0042 | 0.0355 | 0.1197 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0011 | 0.0045 | 0.0248 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0978 | 0.2742 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.1359 | 0.4601 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.018 | 0.0505 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.031 | 0.1044 |
Brugia malayi | beta-lactamase | 0.0037 | 0.031 | 0.087 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0159 | 0.0446 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.031 | 0.1795 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0016 | 0.0089 | 0.5732 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0011 | 0.0045 | 0.0248 |
Loa Loa (eye worm) | low-density lipoprotein receptor domain class A containing protein | 0.0007 | 0.0001 | 0.0003 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0011 | 0.0045 | 0.0144 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0037 | 0.0305 | 0.0856 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0354 | 0.1191 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0025 | 0.0181 | 0.0604 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0025 | 0.018 | 0.2208 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0297 | 0.295 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.018 | 0.1169 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.031 | 0.031 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0042 | 0.0355 | 0.2324 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.002 | 0.0055 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0021 | 0.0142 | 0.0471 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0023 | 0.0159 | 0.0446 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0086 | 0.0806 | 0.0806 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0025 | 0.0181 | 0.3298 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0024 | 0.0177 | 0.0496 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.018 | 0.0751 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0142 | 0.0471 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0021 | 0.0142 | 0.2572 |
Toxoplasma gondii | thioredoxin reductase | 0.006 | 0.0542 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0025 | 0.0181 | 0.0181 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0021 | 0.0145 | 0.0145 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0011 | 0.0045 | 0.0045 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.0551 | 0.0551 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0016 | 0.0089 | 0.1607 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0011 | 0.0045 | 0.0144 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0292 | 0.0292 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0016 | 0.0089 | 0.5732 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.0009 | 0.002 | 0.0312 |
Echinococcus multilocularis | smad | 0.0024 | 0.0177 | 0.0177 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0007 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.016 | 0.0448 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.018 | 0.1197 |
Brugia malayi | MH1 domain containing protein | 0.0013 | 0.0066 | 0.0185 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.0009 | 0.002 | 0.0098 |
Loa Loa (eye worm) | RNA binding protein | 0.0056 | 0.0504 | 0.1413 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.0009 | 0.002 | 0.0312 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0015 | 0.0085 | 0.0239 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0023 | 0.016 | 0.016 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0153 | 0.1484 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.005 | 0.044 | 0.2882 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0024 | 0.0177 | 0.0177 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0016 | 0.0089 | 0.0506 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0071 | 0.0657 | 0.184 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0024 | 0.0177 | 0.0177 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.031 | 0.1795 |
Loa Loa (eye worm) | intermediate filament protein | 0.0063 | 0.0569 | 0.1596 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0137 | 0.1328 | 0.561 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0117 | 0.0327 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.006 | 0.0542 | 0.0542 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0021 | 0.0142 | 0.0397 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0007 | 0.0001 | 0.0003 |
Brugia malayi | MH1 domain containing protein | 0.0013 | 0.0066 | 0.0185 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.031 | 0.2027 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0137 | 0.1328 | 0.561 |
Echinococcus multilocularis | tumor protein p63 | 0.0502 | 0.504 | 0.504 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.031 | 0.1795 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0007 | 0.0001 | 0.0003 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0007 | 0.0001 | 0.0003 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.031 | 0.031 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0023 | 0.0159 | 0.0446 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.031 | 0.087 |
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0007 | 0.0001 | 0.0003 |
Onchocerca volvulus | Terribly reduced optic lobes homolog | 0.0007 | 0.0001 | 0.0003 |
Onchocerca volvulus | 0.0063 | 0.0569 | 0.1678 | |
Echinococcus granulosus | basement membrane specific heparan sulfate | 0.0007 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0025 | 0.0181 | 0.0507 |
Brugia malayi | Thioredoxin reductase | 0.006 | 0.0542 | 0.152 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0024 | 0.0177 | 0.0177 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0021 | 0.0142 | 0.0471 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.018 | 0.2208 |
Brugia malayi | DKFZp564C0469 protein | 0.0009 | 0.002 | 0.0055 |
Leishmania major | protein kinase, putative | 0.0011 | 0.0045 | 0.0144 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.2997 | 0.2997 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.018 | 0.0751 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0021 | 0.0142 | 0.0471 |
Onchocerca volvulus | 0.0025 | 0.018 | 0.0531 | |
Brugia malayi | intermediate filament protein | 0.0063 | 0.0569 | 0.1596 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.005 | 0.044 | 0.044 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0305 | 0.0856 |
Plasmodium vivax | glutathione reductase, putative | 0.006 | 0.0542 | 1 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.005 | 0.044 | 0.044 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0426 | 0.0426 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0218 | 0.0612 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0037 | 0.0305 | 0.0305 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0011 | 0.0045 | 0.0144 |
Onchocerca volvulus | 0.0063 | 0.0569 | 0.1678 | |
Mycobacterium leprae | Possible regulatory protein | 0.0011 | 0.0045 | 0.0287 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.031 | 0.087 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0024 | 0.0177 | 0.0496 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.018 | 0.0505 |
Schistosoma mansoni | ap endonuclease | 0.0016 | 0.0089 | 0.0089 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.018 | 0.1169 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.031 | 0.1795 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0042 | 0.0355 | 0.2324 |
Echinococcus multilocularis | protein dispatched 1 | 0.0042 | 0.0359 | 0.0359 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.002 | 0.0055 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.018 | 0.1169 |
Schistosoma mansoni | smad | 0.0024 | 0.0177 | 0.0177 |
Onchocerca volvulus | 0.0037 | 0.031 | 0.0915 | |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0021 | 0.0142 | 0.0915 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0009 | 0.002 | 0.0098 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0011 | 0.0045 | 0.0248 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Brugia malayi | RNA binding protein | 0.0056 | 0.0504 | 0.1413 |
Onchocerca volvulus | 0.0007 | 0.0001 | 0.0003 | |
Echinococcus granulosus | GPCR family 2 | 0.0023 | 0.0159 | 0.0159 |
Schistosoma mansoni | DNA ligase IV | 0.0009 | 0.002 | 0.002 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.1359 | 0.4601 |
Echinococcus multilocularis | Smad4 | 0.0024 | 0.0177 | 0.0177 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0025 | 0.0181 | 0.0181 |
Echinococcus multilocularis | expressed conserved protein | 0.0081 | 0.0753 | 0.0753 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0025 | 0.0181 | 0.3298 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0117 | 0.0327 |
Schistosoma mansoni | lamin | 0.0063 | 0.0569 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0045 | 0.0127 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0235 | 0.0235 |
Echinococcus multilocularis | lamin dm0 | 0.0063 | 0.0569 | 0.0569 |
Mycobacterium ulcerans | hypothetical protein | 0.0156 | 0.152 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.0502 | 0.504 | 0.504 |
Brugia malayi | hypothetical protein | 0.0009 | 0.002 | 0.0055 |
Echinococcus granulosus | 5'partial|Low density lipoprotein receptor class A cysteine rich | 0.0007 | 0.0001 | 0.0001 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0106 | 0.0439 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0357 | 0.3567 | 0.3567 |
Loa Loa (eye worm) | low-density lipoprotein receptor domain class A containing protein | 0.0007 | 0.0001 | 0.0003 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0023 | 0.016 | 0.016 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.0009 | 0.002 | 0.0209 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0021 | 0.0142 | 0.0142 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0034 | 0.0272 | 0.0763 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0023 | 0.0159 | 0.0159 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0011 | 0.004 | 0.0112 |
Onchocerca volvulus | 0.0007 | 0.0001 | 0.0003 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0297 | 0.295 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0009 | 0.002 | 0.0098 |
Brugia malayi | Pre-SET motif family protein | 0.0154 | 0.1501 | 0.4206 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0009 | 0.002 | 0.0098 |
Echinococcus multilocularis | Low density lipoprotein receptor, class A, cysteine rich | 0.0007 | 0.0001 | 0.0001 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0042 | 0.0355 | 0.0355 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0025 | 0.0181 | 0.0604 |
Echinococcus multilocularis | lamin | 0.0063 | 0.0569 | 0.0569 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.0106 | 0.0439 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0011 | 0.0045 | 0.0045 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0016 | 0.0089 | 0.0089 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0011 | 0.0045 | 0.0248 |
Plasmodium vivax | SET domain protein, putative | 0.0023 | 0.016 | 0.2911 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0021 | 0.0142 | 0.081 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0297 | 0.295 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.014 | 0.1359 | 0.4601 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0025 | 0.0181 | 0.3298 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0025 | 0.0181 | 0.0604 |
Schistosoma mansoni | lamin | 0.0063 | 0.0569 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0003 | 0.0008 |
Echinococcus granulosus | intermediate filament protein | 0.0063 | 0.0569 | 0.0569 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0027 | 0.0027 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0044 | 0.0376 | 0.0376 |
Schistosoma mansoni | smad1 5 8 and | 0.0024 | 0.0177 | 0.0177 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0037 | 0.0305 | 0.0305 |
Brugia malayi | MH2 domain containing protein | 0.0011 | 0.004 | 0.0112 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0357 | 0.3566 | 0.9995 |
Loa Loa (eye worm) | hypothetical protein | 0.0007 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0569 | 0.1596 |
Plasmodium falciparum | glutathione reductase | 0.0021 | 0.0142 | 0.2572 |
Trypanosoma brucei | trypanothione reductase | 0.006 | 0.0542 | 0.1831 |
Echinococcus multilocularis | geminin | 0.0301 | 0.2997 | 0.2997 |
Onchocerca volvulus | Basement membrane proteoglycan homolog | 0.0007 | 0.0001 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.031 | 0.087 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0023 | 0.016 | 0.016 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0235 | 0.0235 |
Brugia malayi | Low-density lipoprotein receptor domain class A containing protein | 0.0007 | 0.0001 | 0.0003 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0007 | 0.0001 | 0.0001 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.031 | 0.031 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0021 | 0.0142 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.031 | 0.1302 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0357 | 0.3566 | 0.9995 |
Brugia malayi | hypothetical protein | 0.0357 | 0.3567 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0025 | 0.0181 | 0.0181 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | Anticonvulsant activity in mouse at 300 mg/kg, ip after 120 mins by MES test | ChEMBL. | 19679472 | |
Activity (functional) | Anticonvulsant activity in mouse at 300 mg/kg, ip after 5 mins by MES test | ChEMBL. | 19679472 | |
Activity (functional) | Anticonvulsant activity in mouse at 300 mg/kg, ip after 15 mins by MES test | ChEMBL. | 19679472 | |
Activity (functional) | Anticonvulsant activity in mouse at 300 mg/kg, ip after 30 mins by MES test | ChEMBL. | 19679472 | |
Activity (functional) | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells after 24 hrs by dual-luciferase assay relative to control | ChEMBL. | 22472691 | |
Activity (functional) | Anticonvulsant activity in mouse at 300 mg/kg, ip after 60 mins by MES test | ChEMBL. | 19679472 | |
FC (functional) | = 0.896 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 1 uM after 24 hrs by dual-luciferase assay relative to control | ChEMBL. | 22472691 |
FC (functional) | = 0.911 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 0.1 uM after 24 hrs by dual-luciferase assay relative to control | ChEMBL. | 22472691 |
FC (functional) | = 1.128 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 5 uM after 24 hrs by dual-luciferase assay relative to control | ChEMBL. | 22472691 |
FC (functional) | = 1.168 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 25 uM after 24 hrs by dual-luciferase assay relative to control | ChEMBL. | 22472691 |
FC (functional) | = 1.2 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 10 uM after 24 hrs by dual-luciferase assay relative to control | ChEMBL. | 22472691 |
FC (functional) | = 1.389 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 50 uM after 24 hrs by dual-luciferase assay relative to control | ChEMBL. | 22472691 |
FC (functional) | = 2.669 | Agonist activity at human farnesoid X receptor expressed in human HepG2 cells at 100 uM after 24 hrs by dual-luciferase assay relative to control | ChEMBL. | 22472691 |
IC50 (functional) | = 125.5 uM | Cytotoxicity against human MDA-MB-231 cells assessed as cell viability after 72 hrs by Alamar Blue assay | ChEMBL. | 26651537 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.