Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | MH1 domain containing protein | 0.0035 | 0.0059 | 0.0079 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0225 | 0.1347 | 0.1891 |
Onchocerca volvulus | 0.0225 | 0.1347 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0003 | 0.0005 |
Entamoeba histolytica | hypothetical protein | 0.0455 | 0.291 | 0.5 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.007 | 0.0298 | 0.0295 |
Schistosoma mansoni | tar DNA-binding protein | 0.0404 | 0.2565 | 0.3604 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.0285 | 0.0282 |
Trichomonas vaginalis | esterase, putative | 0.0225 | 0.1347 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.007 | 0.0298 | 0.2135 |
Onchocerca volvulus | 0.022 | 0.1313 | 0.9742 | |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0225 | 0.1347 | 0.1133 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.007 | 0.0298 | 0.2135 |
Brugia malayi | MH2 domain containing protein | 0.0511 | 0.3289 | 0.4622 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0035 | 0.0059 | 0.0083 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.007 | 0.0298 | 0.2135 |
Trypanosoma brucei | trypanothione reductase | 0.0202 | 0.1193 | 0.884 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.1074 | 0.7112 | 1 |
Onchocerca volvulus | 0.003 | 0.0026 | 0.0169 | |
Toxoplasma gondii | thioredoxin reductase | 0.0202 | 0.1193 | 0.1662 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.0285 | 0.0282 |
Loa Loa (eye worm) | RNA binding protein | 0.0404 | 0.2565 | 0.3607 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0035 | 0.0059 | 0.0056 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.008 | 0.0107 |
Schistosoma mansoni | smad1 5 8 and | 0.0035 | 0.0059 | 0.0079 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.046 | 0.2947 | 0.286 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0102 | 0.071 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.008 | 0.0112 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.007 | 0.0298 | 0.2135 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.0285 | 0.0396 |
Onchocerca volvulus | 0.0225 | 0.1347 | 1 | |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.0285 | 0.0401 |
Leishmania major | hypothetical protein, conserved | 0.0225 | 0.1347 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.1313 | 0.1846 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0225 | 0.1347 | 0.1345 |
Brugia malayi | beta-lactamase family protein | 0.0225 | 0.1347 | 0.1891 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0225 | 0.1347 | 0.1133 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0013 | 0.0013 |
Brugia malayi | beta-lactamase family protein | 0.0225 | 0.1347 | 0.1891 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.007 | 0.0298 | 0.2135 |
Schistosoma mansoni | smad | 0.0035 | 0.0059 | 0.0079 |
Trichomonas vaginalis | glutathione reductase, putative | 0.007 | 0.0298 | 0.2172 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0225 | 0.1347 | 0.1133 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.1347 | 0.1895 |
Plasmodium falciparum | glutathione reductase | 0.0202 | 0.1193 | 0.1662 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0082 | 0.0111 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0225 | 0.1347 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.1435 | 0.9562 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0455 | 0.291 | 0.4089 |
Schistosoma mansoni | thyroid hormone receptor | 0.0145 | 0.0809 | 0.1134 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.007 | 0.0298 | 0.0401 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.046 | 0.2947 | 0.286 |
Toxoplasma gondii | hypothetical protein | 0.037 | 0.2334 | 0.327 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0738 | 0.4828 | 0.4826 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.1347 | 0.1895 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.007 | 0.0298 | 0.2135 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.1074 | 0.7112 | 1 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.0285 | 0.0396 |
Mycobacterium tuberculosis | Conserved protein | 0.0225 | 0.1347 | 0.1133 |
Entamoeba histolytica | hypothetical protein | 0.0455 | 0.291 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0455 | 0.291 | 0.4089 |
Mycobacterium tuberculosis | Conserved protein | 0.0225 | 0.1347 | 0.1133 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.0285 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0013 | 0.0018 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0225 | 0.1347 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0135 | 0.0736 | 0.1031 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.1347 | 0.1895 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0512 | 0.3296 | 0.338 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.0285 | 0.0282 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.0198 | 0.0274 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.0285 | 0.2076 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0102 | 0.0731 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.1074 | 0.7112 | 0.7111 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0225 | 0.1347 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0202 | 0.1193 | 0.119 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0225 | 0.1347 | 0.1133 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0455 | 0.291 | 0.2907 |
Echinococcus granulosus | Smad4 | 0.0035 | 0.0059 | 0.0056 |
Loa Loa (eye worm) | TAR-binding protein | 0.0404 | 0.2565 | 0.3607 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0051 | 0.0172 | 0.0237 |
Mycobacterium ulcerans | beta-lactamase | 0.0225 | 0.1347 | 0.1541 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.037 | 0.2334 | 0.1712 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0225 | 0.1347 | 0.1133 |
Loa Loa (eye worm) | Smad1 | 0.0035 | 0.0059 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0026 | 0.0037 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0202 | 0.1193 | 0.119 |
Trichomonas vaginalis | mercuric reductase, putative | 0.007 | 0.0298 | 0.2172 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.007 | 0.0298 | 0.0414 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0704 | 0.4601 | 0.4645 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.007 | 0.0298 | 0.2135 |
Schistosoma mansoni | tar DNA-binding protein | 0.0404 | 0.2565 | 0.3604 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0511 | 0.3289 | 0.4624 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.007 | 0.0298 | 0.2135 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0003 | 0.0005 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.007 | 0.0298 | 0.0401 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.046 | 0.2947 | 0.286 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.008 | 0.0107 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.1074 | 0.7112 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0082 | 0.0563 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0035 | 0.0059 | 0.0083 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0145 | 0.0809 | 0.0806 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0082 | 0.0585 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0225 | 0.1347 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.007 | 0.0298 | 0.0401 |
Brugia malayi | Thioredoxin reductase | 0.0202 | 0.1193 | 0.1673 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0135 | 0.0736 | 0.0733 |
Brugia malayi | RNA binding protein | 0.0404 | 0.2565 | 0.3604 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.007 | 0.0298 | 0.2135 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0404 | 0.2565 | 0.3607 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.046 | 0.2947 | 0.286 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0404 | 0.2565 | 0.3604 |
Brugia malayi | MH2 domain containing protein | 0.0035 | 0.0059 | 0.0079 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0704 | 0.4601 | 0.5644 |
Brugia malayi | beta-lactamase | 0.0225 | 0.1347 | 0.1891 |
Leishmania major | trypanothione reductase | 0.0202 | 0.1193 | 0.884 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0225 | 0.1347 | 0.1133 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0225 | 0.1347 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0225 | 0.1347 | 0.1891 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0035 | 0.0059 | 0.0056 |
Brugia malayi | Probable ClpP-like protease | 0.1074 | 0.7112 | 1 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.007 | 0.0298 | 0.0401 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.037 | 0.2334 | 0.327 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0051 | 0.0172 | 0.0237 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0225 | 0.1347 | 0.1133 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0225 | 0.1347 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.0285 | 0.0396 |
Plasmodium falciparum | glutathione reductase | 0.007 | 0.0298 | 0.0401 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.1074 | 0.7112 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.1074 | 0.7112 | 1 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.1074 | 0.7112 | 1 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.1074 | 0.7112 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0082 | 0.0115 |
Brugia malayi | Smad1 | 0.0035 | 0.0059 | 0.0079 |
Onchocerca volvulus | 0.0225 | 0.1347 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.1347 | 0.1895 |
Toxoplasma gondii | ABC1 family protein | 0.0225 | 0.1347 | 0.188 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0225 | 0.1347 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0738 | 0.4828 | 0.6787 |
Brugia malayi | glutathione reductase | 0.0202 | 0.1193 | 0.1673 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.0198 | 0.0279 |
Schistosoma mansoni | thyroid hormone receptor | 0.0145 | 0.0809 | 0.1134 |
Schistosoma mansoni | Smad4 | 0.0035 | 0.0059 | 0.0079 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0102 | 0.071 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0225 | 0.1347 | 0.1345 |
Schistosoma mansoni | smad1 5 8 and | 0.0035 | 0.0059 | 0.0079 |
Plasmodium vivax | hypothetical protein, conserved | 0.0225 | 0.1347 | 0.188 |
Echinococcus granulosus | smad | 0.0035 | 0.0059 | 0.0056 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.007 | 0.0298 | 0.0295 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.007 | 0.0298 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0003 | 0.0005 |
Brugia malayi | MH1 domain containing protein | 0.0035 | 0.0059 | 0.0079 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0225 | 0.1347 | 0.1895 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0511 | 0.3289 | 0.4624 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0035 | 0.0059 | 0.0056 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0704 | 0.4601 | 0.4599 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.007 | 0.0298 | 0.2135 |
Echinococcus multilocularis | Smad4 | 0.0035 | 0.0059 | 0.0056 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0135 | 0.0736 | 0.0733 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0704 | 0.4601 | 0.4599 |
Mycobacterium tuberculosis | Probable reductase | 0.046 | 0.2947 | 0.286 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0202 | 0.1193 | 0.1662 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0202 | 0.1193 | 0.884 |
Brugia malayi | MH2 domain containing protein | 0.0035 | 0.0059 | 0.0079 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0704 | 0.4601 | 0.4645 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.007 | 0.0298 | 0.2135 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.007 | 0.0298 | 0.2135 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0225 | 0.1347 | 0.1891 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.037 | 0.2334 | 0.327 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.1074 | 0.7112 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0512 | 0.3296 | 0.3236 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0225 | 0.1347 | 0.1541 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.007 | 0.0298 | 0.0401 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.1074 | 0.7112 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0225 | 0.1347 | 0.1541 |
Echinococcus multilocularis | tar DNA binding protein | 0.0404 | 0.2565 | 0.2563 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.046 | 0.2947 | 0.286 |
Loa Loa (eye worm) | glutathione reductase | 0.0202 | 0.1193 | 0.1677 |
Mycobacterium ulcerans | hypothetical protein | 0.0225 | 0.1347 | 0.1541 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.1074 | 0.7112 | 0.7111 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.007 | 0.0298 | 0.0401 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.1074 | 0.7112 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0202 | 0.1193 | 0.1662 |
Plasmodium vivax | glutathione reductase, putative | 0.0202 | 0.1193 | 0.1662 |
Loa Loa (eye worm) | hypothetical protein | 0.1074 | 0.7112 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.046 | 0.2947 | 0.2775 |
Brugia malayi | TAR-binding protein | 0.0404 | 0.2565 | 0.3604 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.007 | 0.0298 | 0.0401 |
Schistosoma mansoni | tar DNA-binding protein | 0.0404 | 0.2565 | 0.3604 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.1074 | 0.7112 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0404 | 0.2565 | 0.3604 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0202 | 0.1193 | 0.1677 |
Brugia malayi | hypothetical protein | 0.0455 | 0.291 | 0.4089 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0082 | 0.0563 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.007 | 0.0298 | 0.2135 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0035 | 0.0059 | 0.0056 |
Schistosoma mansoni | tar DNA-binding protein | 0.0404 | 0.2565 | 0.3604 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0202 | 0.1193 | 0.0966 |
Loa Loa (eye worm) | beta-lactamase | 0.0225 | 0.1347 | 0.1895 |
Mycobacterium tuberculosis | Conserved protein | 0.0225 | 0.1347 | 0.1133 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.007 | 0.0298 | 0.2135 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.007 | 0.0298 | 0.0414 |
Entamoeba histolytica | hypothetical protein | 0.0455 | 0.291 | 0.5 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.007 | 0.0298 | 0.2135 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.007 | 0.0298 | 0.2135 |
Echinococcus multilocularis | smad | 0.0035 | 0.0059 | 0.0056 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0035 | 0.0059 | 0.0079 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.1074 | 0.7112 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.007 | 0.0298 | 0.2135 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.037 | 0.2334 | 0.2989 |
Schistosoma mansoni | smad1 5 8 and | 0.0035 | 0.0059 | 0.0079 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.0285 | 0.2076 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0455 | 0.291 | 0.2907 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0512 | 0.3296 | 0.3236 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0512 | 0.3296 | 0.3236 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.022 | 0.1313 | 0.1842 |
Echinococcus granulosus | tar DNA binding protein | 0.0404 | 0.2565 | 0.2563 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0225 | 0.1347 | 1 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0738 | 0.4828 | 0.4826 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0198 | 0.0279 |
Entamoeba histolytica | hypothetical protein | 0.0455 | 0.291 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.1347 | 0.1895 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 0.1347 | 0.1895 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.0198 | 0.0274 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0225 | 0.1347 | 0.1541 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | > 200 ug ml-1 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 14 days by serial dilution technique | ChEMBL. | 19423196 |
MIC (functional) | > 200 ug ml-1 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 21 days by serial dilution technique | ChEMBL. | 19423196 |
MIC (functional) | > 200 ug ml-1 | Antimycobacterial activity against Mycobacterium tuberculosis H37Rv after 30 days by serial dilution technique | ChEMBL. | 19423196 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.