Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.2475 | 0.6268 | 0.5808 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0147 | 0.0259 | 0.0259 |
Leishmania major | cathepsin L-like protease | 0.2475 | 0.6268 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0286 | 0.0617 | 0.0617 |
Leishmania major | cathepsin L-like protease | 0.2475 | 0.6268 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1114 | 0.2755 | 0.5377 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.2031 | 0.5122 | 0.5122 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.008 | 0.0085 | 0.0085 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0017 | 0.0017 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Plasmodium vivax | vivapain-2 | 0.2031 | 0.5122 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0017 | 0.0017 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0472 | 0.1098 | 0.1991 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.0353 | 0.0353 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.013 | 0.0215 | 0.0375 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0017 | 0.0017 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.013 | 0.0215 | 0.0415 |
Schistosoma mansoni | cathepsin C | 0.0472 | 0.1098 | 0.1098 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0472 | 0.1098 | 0.1991 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0472 | 0.1098 | 0.1098 |
Leishmania major | cathepsin L-like protease | 0.2475 | 0.6268 | 1 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0713 | 0.1719 | 0.3352 |
Echinococcus granulosus | cathepsin l1 | 0.2031 | 0.5122 | 0.5122 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0713 | 0.1719 | 0.1719 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | chromobox protein | 0.008 | 0.0085 | 0.0085 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0185 | 0.0357 | 0.0357 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0472 | 0.1098 | 0.1991 |
Echinococcus multilocularis | cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Schistosoma mansoni | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Echinococcus granulosus | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.2031 | 0.5122 | 1 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Brugia malayi | cathepsin L-like precursor | 0.1389 | 0.3464 | 0.3464 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2475 | 0.6268 | 0.5808 |
Loa Loa (eye worm) | hypothetical protein | 0.0642 | 0.1536 | 0.1536 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1114 | 0.2755 | 0.2755 |
Echinococcus granulosus | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1539 | 0.3851 | 0.3851 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2031 | 0.5122 | 0.452 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Onchocerca volvulus | Cathepsin F homolog | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0472 | 0.1098 | 0.2106 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0472 | 0.1098 | 0.1991 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0017 | 0.0017 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0472 | 0.1098 | 0.1991 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0472 | 0.1098 | 0.2106 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.008 | 0.0085 | 0.0085 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0642 | 0.1536 | 0.0492 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Echinococcus multilocularis | chromobox protein 1 | 0.008 | 0.0085 | 0.0085 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1389 | 0.3464 | 0.3464 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Brugia malayi | Cathepsin L-like precursor | 0.1389 | 0.3464 | 0.3464 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Plasmodium vivax | vivapain-1 | 0.1114 | 0.2755 | 0.529 |
Loa Loa (eye worm) | hypothetical protein | 0.2031 | 0.5122 | 0.5122 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0713 | 0.1719 | 0.1719 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0017 | 0.0017 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Echinococcus granulosus | cathepsin L | 0.0472 | 0.1098 | 0.1098 |
Giardia lamblia | Cysteine protease | 0.0472 | 0.1098 | 0.2427 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.2031 | 0.5122 | 0.5122 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1539 | 0.3851 | 0.312 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.013 | 0.0215 | 0.0215 |
Onchocerca volvulus | Cathepsin L homolog | 0.2031 | 0.5122 | 1 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Schistosoma mansoni | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Brugia malayi | Cathepsin L-like precursor | 0.0642 | 0.1536 | 0.1536 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0557 | 0.1316 | 0.2424 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.2031 | 0.5122 | 0.5122 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.5357 |
Loa Loa (eye worm) | hypothetical protein | 0.0642 | 0.1536 | 0.1536 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0085 | 0.0097 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0642 | 0.1536 | 0.1536 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1389 | 0.3464 | 0.6749 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0472 | 0.1098 | 0.2427 |
Echinococcus granulosus | chromobox protein 1 | 0.008 | 0.0085 | 0.0085 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0713 | 0.1719 | 0.1719 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1114 | 0.2755 | 0.5377 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 0.0097 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1114 | 0.2755 | 0.1862 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0472 | 0.1098 | 0.1991 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Brugia malayi | carbohydrate phosphorylase | 0.013 | 0.0215 | 0.0215 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.0353 | 0.0353 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0916 | 0.2244 | 0.1288 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.013 | 0.0215 | 0.042 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Entamoeba histolytica | cysteine proteinase 2 | 0.1114 | 0.2755 | 0.5357 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.008 | 0.0085 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0097 | 0.0097 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.2031 | 0.5122 | 0.5122 |
Giardia lamblia | Cathepsin B precursor | 0.0472 | 0.1098 | 0.2427 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Giardia lamblia | Cysteine protease | 0.0472 | 0.1098 | 0.2427 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.1862 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.2031 | 0.5122 | 1 |
Giardia lamblia | Hypothetical protein | 0.0472 | 0.1098 | 0.2427 |
Schistosoma mansoni | chromobox protein | 0.008 | 0.0085 | 0.0085 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0472 | 0.1098 | 0.1991 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0695 | 0.1672 | 0.3134 |
Onchocerca volvulus | 0.1389 | 0.3464 | 0.6764 | |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0017 | 0.0017 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0695 | 0.1672 | 0.4007 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.2031 | 0.5122 | 1 |
Echinococcus granulosus | cysteine protease | 0.1114 | 0.2755 | 0.2755 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Echinococcus multilocularis | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0185 | 0.0357 | 0.0357 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Echinococcus multilocularis | geminin | 0.0184 | 0.0353 | 0.0353 |
Giardia lamblia | Cathepsin B precursor | 0.0472 | 0.1098 | 0.2427 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.1389 | 0.3464 | 0.3464 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Loa Loa (eye worm) | cathepsin B | 0.1539 | 0.3851 | 0.3851 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0259 | 0.0259 |
Giardia lamblia | Cathepsin B precursor | 0.1539 | 0.3851 | 1 |
Plasmodium vivax | vivapain-3 | 0.1114 | 0.2755 | 0.529 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0713 | 0.1719 | 0.3352 |
Giardia lamblia | Cysteine protease | 0.0472 | 0.1098 | 0.2427 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2475 | 0.6268 | 0.5808 |
Plasmodium vivax | unspecified product | 0.0472 | 0.1098 | 0.1991 |
Schistosoma mansoni | glycogen phosphorylase | 0.0056 | 0.0024 | 0.0024 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Plasmodium vivax | unspecified product | 0.1114 | 0.2755 | 0.529 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Echinococcus granulosus | cathepsin L | 0.1114 | 0.2755 | 0.2755 |
Onchocerca volvulus | 0.0472 | 0.1098 | 0.2143 | |
Trypanosoma cruzi | cysteine protease, putative | 0.1114 | 0.2755 | 0.1862 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Brugia malayi | Probable ClpP-like protease | 0.0085 | 0.0097 | 0.0097 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0713 | 0.1719 | 0.3352 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0472 | 0.1098 | 0.1991 |
Giardia lamblia | Cathepsin B precursor | 0.0472 | 0.1098 | 0.2427 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Toxoplasma gondii | cathepsin CPC2 | 0.0557 | 0.1316 | 0.2424 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0695 | 0.1672 | 0.1672 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0472 | 0.1098 | 0.2106 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Giardia lamblia | Cathepsin B precursor | 0.0713 | 0.1719 | 0.4135 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0472 | 0.1098 | 0.2139 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1114 | 0.2755 | 0.2755 |
Loa Loa (eye worm) | fibroinase | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.1114 | 0.2755 | 0.529 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0695 | 0.1672 | 0.3134 |
Leishmania major | cysteine peptidase A (CPA) | 0.2031 | 0.5122 | 0.5258 |
Schistosoma mansoni | cathepsin s | 0.0642 | 0.1536 | 0.1536 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Plasmodium vivax | unspecified product | 0.0642 | 0.1536 | 0.2863 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.2031 | 0.5122 | 0.5122 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 0.5 |
Giardia lamblia | Cathepsin L-like protease | 0.0472 | 0.1098 | 0.2427 |
Echinococcus multilocularis | muscleblind protein | 0.0147 | 0.0259 | 0.0259 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0713 | 0.1719 | 0.3352 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0642 | 0.1536 | 0.1536 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0017 | 0.0017 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0472 | 0.1098 | 0.1098 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Brugia malayi | Cathepsin L-like precursor | 0.1389 | 0.3464 | 0.3464 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.1833 | 0.4611 | 0.3946 |
Giardia lamblia | Cysteine protease | 0.0472 | 0.1098 | 0.2427 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0048 | 0.0003 | 0.0006 |
Giardia lamblia | Cathepsin L-like protease | 0.0472 | 0.1098 | 0.2427 |
Brugia malayi | cathepsin L precursor | 0.0472 | 0.1098 | 0.1098 |
Giardia lamblia | Encystation-specific protease | 0.0557 | 0.1316 | 0.3027 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.013 | 0.0215 | 0.0415 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | chromobox protein, putative | 0.008 | 0.0085 | 0.016 |
Trichomonas vaginalis | chromobox protein, putative | 0.008 | 0.0085 | 0.016 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0695 | 0.1672 | 0.3134 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.1114 | 0.2755 | 0.2755 |
Giardia lamblia | Cathepsin B precursor | 0.0472 | 0.1098 | 0.2427 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0472 | 0.1098 | 0.1991 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.5357 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1114 | 0.2755 | 0.2755 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1389 | 0.3464 | 0.6762 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0056 | 0.0024 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Echinococcus granulosus | muscleblind protein | 0.0147 | 0.0259 | 0.0259 |
Toxoplasma gondii | cathepsin B | 0.1539 | 0.3851 | 0.7471 |
Entamoeba histolytica | cysteine protease, putative | 0.2031 | 0.5122 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0266 | 0.0564 | 0.0564 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.5357 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0056 | 0.0022 | 0.0022 |
Giardia lamblia | Cathepsin B precursor | 0.1539 | 0.3851 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Echinococcus granulosus | cathepsin l1 | 0.1389 | 0.3464 | 0.3464 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0472 | 0.1098 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0642 | 0.1536 | 0.1536 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Onchocerca volvulus | Cathepsin L homolog | 0.0472 | 0.1098 | 0.2143 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.008 | 0.0085 | 0.0085 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.061 | 0.1454 | 0.2835 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.1114 | 0.2755 | 0.1862 |
Chlamydia trachomatis | glycogen phosphorylase | 0.013 | 0.0215 | 1 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.013 | 0.0215 | 0.0215 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.2031 | 0.5122 | 0.5122 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0017 | 0.0017 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.1862 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0472 | 0.1098 | 0.2139 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0695 | 0.1672 | 0.3134 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.5357 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.1114 | 0.2755 | 0.5357 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0266 | 0.0564 | 0.0564 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1539 | 0.3851 | 0.3093 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0472 | 0.1098 | 0.1991 |
Entamoeba histolytica | cysteine proteinase, putative | 0.2031 | 0.5122 | 1 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0056 | 0.0022 | 0.0022 |
Plasmodium vivax | vivapain-2 | 0.2031 | 0.5122 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0147 | 0.0259 | 0.0259 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0472 | 0.1098 | 0.1991 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.013 | 0.0215 | 0.0375 |
Giardia lamblia | Cathepsin B precursor | 0.1539 | 0.3851 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0259 | 0.0259 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0085 | 0.0097 | 0.0097 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Echinococcus multilocularis | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1389 | 0.3464 | 0.6762 |
Loa Loa (eye worm) | ctsf protein | 0.2031 | 0.5122 | 0.5122 |
Echinococcus multilocularis | cathepsin L | 0.0472 | 0.1098 | 0.1098 |
Toxoplasma gondii | cathepsin CPC1 | 0.0695 | 0.1672 | 0.3134 |
Loa Loa (eye worm) | hypothetical protein | 0.1389 | 0.3464 | 0.3464 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0472 | 0.1098 | 0.1991 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0695 | 0.1672 | 0.3134 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0557 | 0.1316 | 0.3027 |
Echinococcus granulosus | geminin | 0.0184 | 0.0353 | 0.0353 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0557 | 0.1316 | 0.2424 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 0.5 |
Giardia lamblia | Hypothetical protein | 0.0472 | 0.1098 | 0.2427 |
Loa Loa (eye worm) | hypothetical protein | 0.1389 | 0.3464 | 0.3464 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1539 | 0.3851 | 0.7517 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0642 | 0.1536 | 0.1536 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1389 | 0.3464 | 0.3464 |
Brugia malayi | fibroinase precursor | 0.0472 | 0.1098 | 0.1098 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1114 | 0.2755 | 0.2755 |
Echinococcus multilocularis | cathepsin L | 0.1114 | 0.2755 | 0.2755 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Entamoeba histolytica | cysteine proteinase, putative | 0.2031 | 0.5122 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.2031 | 0.5122 | 0.5122 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1114 | 0.2755 | 0.2755 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0557 | 0.1316 | 0.3027 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2475 | 0.6268 | 0.5808 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0642 | 0.1536 | 0.0492 |
Onchocerca volvulus | Cathepsin L homolog | 0.2031 | 0.5122 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 55.6 uM | Inhibition of rabbit muscle glycogen phosphorylase A assessed as release of phosphate from glucose-1-phosphate after 25 mins | ChEMBL. | 19889536 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.