Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | peptidase Clp S14 family | 0.0056 | 0.0022 | 0.0022 |
Echinococcus granulosus | geminin | 0.0184 | 0.0353 | 0.0353 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1389 | 0.3464 | 0.6749 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.2031 | 0.5122 | 0.5122 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0085 | 0.0097 | 0.0097 |
Giardia lamblia | Cathepsin B precursor | 0.0472 | 0.1098 | 0.2427 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.2031 | 0.5122 | 0.5122 |
Entamoeba histolytica | cysteine protease, putative | 0.2031 | 0.5122 | 1 |
Plasmodium vivax | unspecified product | 0.0472 | 0.1098 | 0.1991 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0695 | 0.1672 | 0.3134 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2475 | 0.6268 | 0.5808 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.1389 | 0.3464 | 0.3464 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1114 | 0.2755 | 0.5377 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0472 | 0.1098 | 0.1991 |
Giardia lamblia | Cathepsin B precursor | 0.0472 | 0.1098 | 0.2427 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Onchocerca volvulus | Cathepsin L homolog | 0.0472 | 0.1098 | 0.2143 |
Loa Loa (eye worm) | hypothetical protein | 0.0642 | 0.1536 | 0.1536 |
Plasmodium vivax | vivapain-2 | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.013 | 0.0215 | 0.0415 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0472 | 0.1098 | 0.2139 |
Plasmodium vivax | unspecified product | 0.1114 | 0.2755 | 0.529 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.2031 | 0.5122 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0557 | 0.1316 | 0.3027 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Schistosoma mansoni | cathepsin C | 0.0472 | 0.1098 | 0.1098 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.013 | 0.0215 | 0.0375 |
Brugia malayi | cathepsin L precursor | 0.0472 | 0.1098 | 0.1098 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0916 | 0.2244 | 0.1288 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0713 | 0.1719 | 0.3352 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.1862 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0713 | 0.1719 | 0.3352 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Giardia lamblia | Cathepsin B precursor | 0.1539 | 0.3851 | 1 |
Giardia lamblia | Cysteine protease | 0.0472 | 0.1098 | 0.2427 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0472 | 0.1098 | 0.2106 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.008 | 0.0085 | 0.016 |
Echinococcus multilocularis | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Giardia lamblia | Cathepsin B precursor | 0.1539 | 0.3851 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.1833 | 0.4611 | 0.3946 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.0353 | 0.0353 |
Brugia malayi | Heterochromatin protein 1 | 0.008 | 0.0085 | 0.0085 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Brugia malayi | cathepsin L-like precursor | 0.1389 | 0.3464 | 0.3464 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Plasmodium vivax | vivapain-3 | 0.1114 | 0.2755 | 0.529 |
Onchocerca volvulus | Cathepsin L homolog | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0147 | 0.0259 | 0.0259 |
Loa Loa (eye worm) | hypothetical protein | 0.2031 | 0.5122 | 0.5122 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2475 | 0.6268 | 0.5808 |
Loa Loa (eye worm) | hypothetical protein | 0.0642 | 0.1536 | 0.1536 |
Echinococcus granulosus | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Giardia lamblia | Hypothetical protein | 0.0472 | 0.1098 | 0.2427 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1114 | 0.2755 | 0.5377 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Toxoplasma gondii | cathepsin CPC1 | 0.0695 | 0.1672 | 0.3134 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0472 | 0.1098 | 0.1098 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.5357 |
Echinococcus granulosus | cathepsin l1 | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.1114 | 0.2755 | 0.5357 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 0.5 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0472 | 0.1098 | 0.1991 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0642 | 0.1536 | 0.1536 |
Onchocerca volvulus | Cathepsin L homolog | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0695 | 0.1672 | 0.1672 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0713 | 0.1719 | 0.1719 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0642 | 0.1536 | 0.0492 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.2475 | 0.6268 | 0.5808 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.061 | 0.1454 | 0.2835 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0472 | 0.1098 | 0.1991 |
Brugia malayi | follicle stimulating hormone receptor | 0.0266 | 0.0564 | 0.0564 |
Schistosoma mansoni | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0695 | 0.1672 | 0.3134 |
Echinococcus granulosus | chromobox protein 1 | 0.008 | 0.0085 | 0.0085 |
Echinococcus granulosus | chromobox protein 1 | 0.008 | 0.0085 | 0.0085 |
Echinococcus multilocularis | cathepsin L | 0.0472 | 0.1098 | 0.1098 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0259 | 0.0259 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Echinococcus granulosus | cathepsin L | 0.0472 | 0.1098 | 0.1098 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0472 | 0.1098 | 0.1991 |
Echinococcus multilocularis | chromobox protein 1 | 0.008 | 0.0085 | 0.0085 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0472 | 0.1098 | 0.1991 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0472 | 0.1098 | 0.1991 |
Echinococcus granulosus | cathepsin l1 | 0.1389 | 0.3464 | 0.3464 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Plasmodium vivax | unspecified product | 0.0642 | 0.1536 | 0.2863 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0713 | 0.1719 | 0.1719 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0472 | 0.1098 | 0.1991 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Toxoplasma gondii | cathepsin B | 0.1539 | 0.3851 | 0.7471 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1114 | 0.2755 | 0.1862 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1389 | 0.3464 | 0.6762 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0472 | 0.1098 | 0.1098 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.2031 | 0.5122 | 0.5122 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Trichomonas vaginalis | chromobox protein, putative | 0.008 | 0.0085 | 0.016 |
Echinococcus multilocularis | cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Echinococcus granulosus | cathepsin L | 0.1114 | 0.2755 | 0.2755 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.013 | 0.0215 | 0.0215 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0185 | 0.0357 | 0.0357 |
Giardia lamblia | Cathepsin B precursor | 0.0472 | 0.1098 | 0.2427 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0642 | 0.1536 | 0.1536 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0713 | 0.1719 | 0.3352 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Brugia malayi | Probable ClpP-like protease | 0.0085 | 0.0097 | 0.0097 |
Echinococcus multilocularis | chromobox protein 1 | 0.008 | 0.0085 | 0.0085 |
Giardia lamblia | Cathepsin L precursor | 0.0472 | 0.1098 | 0.2427 |
Onchocerca volvulus | 0.1389 | 0.3464 | 0.6764 | |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0642 | 0.1536 | 0.0492 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0472 | 0.1098 | 0.1991 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0147 | 0.0259 | 0.0259 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0695 | 0.1672 | 0.4007 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0557 | 0.1316 | 0.3027 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.0353 | 0.0353 |
Toxoplasma gondii | cathepsin CPL | 0.2031 | 0.5122 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1389 | 0.3464 | 0.3464 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.0259 | 0.0259 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.2031 | 0.5122 | 0.5122 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0557 | 0.1316 | 0.2424 |
Brugia malayi | Muscleblind-like protein | 0.0147 | 0.0259 | 0.0259 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1389 | 0.3464 | 0.6762 |
Brugia malayi | fibroinase precursor | 0.0472 | 0.1098 | 0.1098 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0056 | 0.0024 | 0.0024 |
Echinococcus granulosus | cysteine protease | 0.1114 | 0.2755 | 0.2755 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0472 | 0.1098 | 0.2139 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.2031 | 0.5122 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.2031 | 0.5122 | 0.5258 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2475 | 0.6268 | 0.5808 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Brugia malayi | carbohydrate phosphorylase | 0.013 | 0.0215 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.1389 | 0.3464 | 0.3464 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1539 | 0.3851 | 0.7517 |
Schistosoma mansoni | cathepsin s | 0.0642 | 0.1536 | 0.1536 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.1862 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0017 | 0.0017 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0472 | 0.1098 | 0.1991 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0048 | 0.0003 | 0.0006 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0017 | 0.0017 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1389 | 0.3464 | 0.3464 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Leishmania major | cathepsin L-like protease | 0.2475 | 0.6268 | 1 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0472 | 0.1098 | 0.1991 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1539 | 0.3851 | 0.312 |
Giardia lamblia | Cathepsin L-like protease | 0.0472 | 0.1098 | 0.2427 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.1114 | 0.2755 | 0.529 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0472 | 0.1098 | 0.2427 |
Giardia lamblia | Cathepsin B precursor | 0.0713 | 0.1719 | 0.4135 |
Brugia malayi | Cathepsin L-like precursor | 0.1389 | 0.3464 | 0.3464 |
Giardia lamblia | Cysteine protease | 0.0472 | 0.1098 | 0.2427 |
Giardia lamblia | Cathepsin L-like protease | 0.0472 | 0.1098 | 0.2427 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0017 | 0.0017 |
Echinococcus multilocularis | cathepsin L | 0.1114 | 0.2755 | 0.2755 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.1114 | 0.2755 | 0.1862 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0713 | 0.1719 | 0.1719 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0017 | 0.0017 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.2031 | 0.5122 | 0.5122 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0472 | 0.1098 | 0.1991 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0557 | 0.1316 | 0.2424 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0472 | 0.1098 | 0.1991 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.2475 | 0.6268 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0266 | 0.0564 | 0.0564 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0642 | 0.1536 | 0.1536 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 0.0097 |
Onchocerca volvulus | 0.0472 | 0.1098 | 0.2143 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0472 | 0.1098 | 0.1098 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0695 | 0.1672 | 0.3134 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1114 | 0.2755 | 0.2755 |
Brugia malayi | Papain family cysteine protease containing protein | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.5357 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0056 | 0.0024 | 1 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0713 | 0.1719 | 0.3352 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Echinococcus multilocularis | muscleblind protein | 0.0147 | 0.0259 | 0.0259 |
Toxoplasma gondii | cathepsin CPC2 | 0.0557 | 0.1316 | 0.2424 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0695 | 0.1672 | 0.3134 |
Loa Loa (eye worm) | fibroinase | 0.2031 | 0.5122 | 0.5122 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.5357 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0472 | 0.1098 | 0.2106 |
Giardia lamblia | Encystation-specific protease | 0.0557 | 0.1316 | 0.3027 |
Entamoeba histolytica | hypothetical protein | 0.0472 | 0.1098 | 0.2106 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0695 | 0.1672 | 0.3134 |
Loa Loa (eye worm) | hypothetical protein | 0.1389 | 0.3464 | 0.3464 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.013 | 0.0215 | 0.0415 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1539 | 0.3851 | 0.3093 |
Brugia malayi | Cathepsin L-like precursor | 0.2031 | 0.5122 | 0.5122 |
Giardia lamblia | Cysteine protease | 0.0472 | 0.1098 | 0.2427 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0472 | 0.1098 | 0.1991 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1114 | 0.2755 | 0.2755 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0472 | 0.1098 | 0.1098 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.1098 | 0.1098 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 1 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0017 | 0.0017 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0185 | 0.0357 | 0.0357 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1114 | 0.2755 | 0.2755 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0097 | 0.0097 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.2031 | 0.5122 | 1 |
Leishmania major | cathepsin L-like protease | 0.2475 | 0.6268 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.013 | 0.0215 | 0.0375 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.013 | 0.0215 | 0.042 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1114 | 0.2755 | 0.2755 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.1114 | 0.2755 | 0.2755 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1114 | 0.2755 | 0.5357 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0472 | 0.1098 | 0.1991 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.1114 | 0.2755 | 0.2755 |
Loa Loa (eye worm) | hypothetical protein | 0.0642 | 0.1536 | 0.1536 |
Schistosoma mansoni | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Leishmania major | cathepsin L-like protease | 0.2031 | 0.5122 | 0.5258 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1539 | 0.3851 | 0.3851 |
Schistosoma mansoni | hypothetical protein | 0.0286 | 0.0617 | 0.0617 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0017 | 0.0017 |
Echinococcus multilocularis | cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Echinococcus multilocularis | glycogen phosphorylase | 0.013 | 0.0215 | 0.0215 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Trypanosoma cruzi | cysteine protease, putative | 0.1114 | 0.2755 | 0.1862 |
Onchocerca volvulus | 0.2031 | 0.5122 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0642 | 0.1536 | 0.1536 |
Giardia lamblia | Hypothetical protein | 0.0472 | 0.1098 | 0.2427 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0017 | 0.0017 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0472 | 0.1098 | 0.1991 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2031 | 0.5122 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.1114 | 0.2755 | 0.5357 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.2031 | 0.5122 | 0.5122 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0056 | 0.0022 | 0.0022 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.1389 | 0.3464 | 0.3464 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Giardia lamblia | Cathepsin B precursor | 0.1539 | 0.3851 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Leishmania major | cathepsin L-like protease | 0.2475 | 0.6268 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0085 | 0.0097 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0472 | 0.1098 | 0.2139 |
Entamoeba histolytica | cysteine protease, putative | 0.1114 | 0.2755 | 0.5357 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Entamoeba histolytica | cysteine proteinase, putative | 0.2031 | 0.5122 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.2031 | 0.5122 | 0.5122 |
Plasmodium vivax | vivapain-1 | 0.1114 | 0.2755 | 0.529 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.2031 | 0.5122 | 0.5122 |
Plasmodium vivax | vivapain-2 | 0.2031 | 0.5122 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.2031 | 0.5122 | 0.5122 |
Schistosoma mansoni | chromobox protein | 0.008 | 0.0085 | 0.0085 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0472 | 0.1098 | 0.1098 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2031 | 0.5122 | 0.452 |
Entamoeba histolytica | cysteine protease, putative | 0.0472 | 0.1098 | 0.2106 |
Giardia lamblia | Cysteine protease | 0.0472 | 0.1098 | 0.2427 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.008 | 0.0085 | 0.0085 |
Echinococcus multilocularis | geminin | 0.0184 | 0.0353 | 0.0353 |
Giardia lamblia | Cathepsin B precursor | 0.0472 | 0.1098 | 0.2427 |
Chlamydia trachomatis | glycogen phosphorylase | 0.013 | 0.0215 | 1 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.0097 | 0.0097 |
Schistosoma mansoni | chromobox protein | 0.008 | 0.0085 | 0.0085 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.013 | 0.0215 | 0.0215 |
Loa Loa (eye worm) | cathepsin B | 0.1539 | 0.3851 | 0.3851 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 55.6 uM | Inhibition of rabbit muscle glycogen phosphorylase A assessed as release of phosphate from glucose-1-phosphate after 25 mins | ChEMBL. | 19889536 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.