Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.4318 | 0.4318 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.2773 | 0.2773 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.2773 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.4318 | 1 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0397 | 0.0397 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.2773 | 0.6421 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.2773 | 0.2773 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.4318 | 1 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0009 | 0.0397 | 0.0919 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.4318 | 1 |
Echinococcus granulosus | expressed protein | 0.0009 | 0.0397 | 0.0397 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.4318 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.2773 | 0.2773 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.4318 | 0.4318 |
Schistosoma mansoni | ferritin light chain | 0.0009 | 0.0397 | 0.0397 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.4318 | 1 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0009 | 0.0397 | 0.5 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.4318 | 0.4318 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0009 | 0.0397 | 0.0919 |
Schistosoma mansoni | apoferritin-2 | 0.0009 | 0.0397 | 0.0397 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.4318 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.2773 | 0.2773 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.4318 | 0.4318 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.2773 | 0.6421 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0009 | 0.0397 | 0.5 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0009 | 0.0397 | 0.0919 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.4318 | 1 |
Schistosoma mansoni | apoferritin-2 | 0.0009 | 0.0397 | 0.0397 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.4318 | 1 |
Schistosoma mansoni | ferritin light chain | 0.0009 | 0.0397 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.2773 | 0.2773 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0397 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.4318 | 0.4318 |
Echinococcus multilocularis | ferritin | 0.0009 | 0.0397 | 0.0397 |
Echinococcus granulosus | ferritin | 0.0009 | 0.0397 | 0.0397 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.2524 | 0.5844 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.4318 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.4318 | 1 |
Echinococcus multilocularis | expressed protein | 0.0009 | 0.0397 | 0.0397 |
Onchocerca volvulus | 0.0024 | 0.4318 | 1 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.4318 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.2773 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.4318 | 0.4318 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0009 | 0.0397 | 0.0919 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.2524 | 0.5844 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.2524 | 0.5844 |
Trichomonas vaginalis | ferritin, putative | 0.0009 | 0.0397 | 1 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0397 | 0.0397 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.2524 | 0.5844 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.2773 | 0.5 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0397 | 0.0397 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.4318 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.4318 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.4318 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.4318 | 1 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0009 | 0.0397 | 0.0919 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.4318 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.4318 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.4318 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.