Detailed information for compound 1074298

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 401.882 | Formula: C19H28ClNO6
  • H donors: 1 H acceptors: 2 LogP: 2.49 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CO[C@@H]1[C@@H](CC[C@@]2([C@@H]1[C@@]1(C)O[C@@H]1CC=C(C)C)CO2)OC(=O)NC(=O)CCl
  • InChi: 1S/C19H28ClNO6/c1-11(2)5-6-13-18(3,27-13)16-15(24-4)12(7-8-19(16)10-25-19)26-17(23)21-14(22)9-20/h5,12-13,15-16H,6-10H2,1-4H3,(H,21,22,23)/t12-,13-,15-,16+,18+,19+/m1/s1
  • InChiKey: MSHZHSPISPJWHW-FRDQJGBZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0092 0.0746
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.1327 0.4479
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0014 0.0003 0.0006
Onchocerca volvulus 0.0015 0.0008 0.0033
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.001 0.0034
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0057 0.0231 0.1908
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0155 0.0155
Plasmodium vivax hypothetical protein, conserved 0.0145 0.0703 0.6214
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0846 0.2854
Echinococcus multilocularis Ankyrin 0.0229 0.1148 0.1644
Giardia lamblia PHD finger protein 15 0.0031 0.0092 0.0302
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0383 0.197 1
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0053 0.0208 0.1711
Loa Loa (eye worm) twinkle helicase 0.0109 0.0511 0.0511
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0155 0.0222
Brugia malayi G protein-coupled receptor 0.0015 0.0008 0.0008
Schistosoma mansoni dep domain containing protein 0.0018 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0145 0.0703 0.0776
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.0008 0.0008
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0017 0.0024
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0121 0.06
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0008 0.002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.024 0.198
Brugia malayi Cytochrome P450 family protein 0.0053 0.0207 0.0207
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0016 0.001 0.0034
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0231 0.1983
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0237 0.1956
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0569 0.2963 1
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0059 0.024 0.198
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0059 0.024 0.2061
Schistosoma mansoni sulfide quinone reductase 0.0016 0.001 0.0024
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0014 0.0003 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.1327 0.4479
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0016 0.001 0.0014
Echinococcus granulosus SNF4:AMP activated protein kinase gamma subunit 0.0014 0.0003 0.0004
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0016 0.001 0.0034
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0373 0.0533
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0057 0.0231 0.1908
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.005 0.005
Brugia malayi MH1 domain containing protein 0.0025 0.0058 0.0058
Echinococcus granulosus importin subunit beta 1 0.0058 0.0237 0.0339
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.0692 0.3622 0.8576
Echinococcus multilocularis Smad4 0.0025 0.0058 0.0083
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0008 0.0012
Leishmania major hypothetical protein, conserved 0.0016 0.001 0.0062
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.0008 0.0012
Schistosoma mansoni microtubule-associated protein tau 0.0691 0.3614 0.8559
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0023 0.005 0.024
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Brugia malayi jmjC domain containing protein 0.0101 0.0467 0.0467
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0017 0.0024
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0367 0.1885 0.7615
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0018 0.0023 0.0033
Brugia malayi ancient conserved domain protein 4 0.0014 0.0003 0.0003
Brugia malayi bZIP transcription factor family protein 0.0053 0.0209 0.0209
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.0008 0.0012
Schistosoma mansoni ap endonuclease 0.0057 0.0231 0.0547
Brugia malayi N-terminal motif family protein 0.0367 0.1885 0.1885
Onchocerca volvulus 0.0015 0.0008 0.0033
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0158 0.13
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.0008 0.0012
Mycobacterium ulcerans dehydrogenase 0.0016 0.001 0.0038
Entamoeba histolytica hypothetical protein 0.0047 0.0178 0.0602
Loa Loa (eye worm) hypothetical protein 0.0016 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Schistosoma mansoni ankyrin 23/unc44 0.0227 0.1139 0.2697
Schistosoma mansoni disulfide oxidoreductase 0.0016 0.001 0.0024
Giardia lamblia Glutamate synthase 0.0016 0.001 0.0025
Echinococcus granulosus Ankyrin 0.0229 0.1148 0.1644
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.0008 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0008 0.002
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0092 0.0132
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0418 0.2159 0.2159
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.001 0.0062
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0014 0.0003 0.0001
Onchocerca volvulus 0.0015 0.0008 0.0033
Echinococcus multilocularis H(+):Cl() exchange transporter 3 0.0014 0.0003 0.0004
Echinococcus multilocularis fos transcription factor 0.0053 0.0209 0.0299
Echinococcus multilocularis H(+):Cl() exchange transporter 4 0.0014 0.0003 0.0004
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0158 0.0227
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0057 0.0231 0.0331
Schistosoma mansoni smad 0.0025 0.0058 0.0137
Schistosoma mansoni methionyl aminopeptidase 2 (M24 family) 0.0053 0.0208 0.0492
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0121 0.0984
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) beta-lactamase 0.0145 0.0703 0.0703
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.1327 0.4479
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0014 0.0003 0.0001
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0016 0.001 0.0038
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0383 0.197 1
Onchocerca volvulus 0.0057 0.0229 0.0923
Echinococcus multilocularis neuropeptide receptor A26 0.0467 0.2419 0.3464
Schistosoma mansoni adenoreceptor 0.0015 0.0008 0.002
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0237 0.0339
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0016 0.001 0.0038
Echinococcus granulosus g-protein coupled receptor 0.0015 0.0008 0.0012
Echinococcus granulosus microtubule associated protein 2 0.0691 0.3614 0.5175
Echinococcus granulosus serotonin receptor 0.0015 0.0008 0.0012
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0052 0.0253
Schistosoma mansoni camp-response element binding protein-related 0.0053 0.0209 0.0495
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0008 0.0012
Brugia malayi G-protein coupled receptor 0.0015 0.0008 0.0008
Echinococcus granulosus Pleckstrin G protein interacting region 0.0018 0.0023 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0008 0.002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0008 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0008 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0008 0.002
Echinococcus granulosus cyclic AMP responsive element binding protein 0.0053 0.0209 0.0299
Schistosoma mansoni glutamate synthase 0.0016 0.001 0.0024
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0016 0.001 0.0034
Schistosoma mansoni Smad4 0.0025 0.0058 0.0137
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.063 0.3287 0.3287
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0016 0.001 0.0014
Brugia malayi hypothetical protein 0.0053 0.0209 0.0209
Onchocerca volvulus 0.0084 0.0373 0.1505
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0326 0.27
Mycobacterium tuberculosis Probable esterase LipL 0.0145 0.0703 0.0776
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.0008 0.0008
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0714 0.0714
Loa Loa (eye worm) hypothetical protein 0.0229 0.1148 0.1148
Brugia malayi G-protein coupled receptor 0.0015 0.0008 0.0008
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0239 0.1201 0.6091
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0023 0.0033
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0231 0.078
Brugia malayi hypothetical protein 0.0015 0.0008 0.0008
Brugia malayi hypothetical protein 0.0048 0.0185 0.0185
Echinococcus granulosus lysine specific demethylase 5A 0.0041 0.0144 0.0206
Schistosoma mansoni neuropeptide receptor 0.0015 0.0008 0.002
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0569 0.2963 1
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.001 0.0062
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.0008 0.002
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.0113 0.0532 0.2035
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0099 0.0456 0.0456
Leishmania major hypothetical protein, conserved 0.0145 0.0703 0.5845
Brugia malayi hypothetical protein 0.0015 0.0008 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0253 0.0598
Brugia malayi Uncoordinated protein 44 0.0227 0.1139 0.1139
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0059 0.024 0.0343
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0016 0.001 0.0014
Loa Loa (eye worm) inositol-1 0.0036 0.0121 0.0121
Echinococcus multilocularis muscleblind protein 0.063 0.3287 0.4707
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.0008 0.0008
Schistosoma mansoni opsin-like receptor 0.0015 0.0008 0.002
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.001 0.0034
Brugia malayi Dopamine receptor 0.0015 0.0008 0.0008
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0016 0.001 0.0062
Schistosoma mansoni chloride channel protein 0.0014 0.0003 0.0006
Brugia malayi Melatonin receptor type 1A 0.0015 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0014 0.0003 0.0001
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0016 0.001 0.0014
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0155 0.0155
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.001 0.0062
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Trypanosoma brucei cytochrome P450, putative 0.0023 0.005 0.0394
Schistosoma mansoni opsin-like receptor 0.0015 0.0008 0.002
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0008 0.0012
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0278 0.141 0.156
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0319 0.1628 0.233
Loa Loa (eye worm) hypothetical protein 0.0075 0.0326 0.0326
Schistosoma mansoni smad1 5 8 and 0.0025 0.0058 0.0137
Schistosoma mansoni hypothetical protein 0.0053 0.0209 0.0495
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0015 0.0008 0.0033
Loa Loa (eye worm) loechrig isoform VII 0.0014 0.0003 0.0003
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0008 0.0012
Brugia malayi Inositol-1 0.0036 0.0121 0.0121
Brugia malayi Serotonin receptor 0.0015 0.0008 0.0008
Echinococcus multilocularis nuclear factor of activated T cells 5 0.1323 0.6984 1
Treponema pallidum NADH oxidase 0.0059 0.024 0.0801
Schistosoma mansoni fos transcription factor-related 0.0053 0.0209 0.0495
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0039
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0239 0.1201 1
Leishmania major inosine-5-monophosphate dehydrogenase 0.0239 0.1201 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.0008 0.0008
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0057 0.0231 0.0331
Treponema pallidum oxidoreductase 0.0016 0.001 0.0025
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0008 0.0012
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0207 0.0207
Echinococcus granulosus cAMP responsive element binding protein 3 0.0053 0.0209 0.0299
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0227 0.1139 0.163
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0039
Schistosoma mansoni biogenic amine receptor 0.0015 0.0008 0.002
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0178 0.0602
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0052 0.0443
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Schistosoma mansoni Replicative DNA helicase 0.0383 0.197 0.4665
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0014 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0008 0.0012
Trypanosoma brucei GMP reductase 0.0239 0.1201 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0121 0.0121
Schistosoma mansoni cpg binding protein 0.006 0.0246 0.0582
Mycobacterium tuberculosis Conserved protein 0.0145 0.0703 0.0776
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0053 0.0208 0.0701
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.0008 0.0008
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.01 0.0375
Echinococcus granulosus beta LACTamase domain containing family member 0.0145 0.0703 0.1006
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0262 0.1327 0.1327
Schistosoma mansoni hypothetical protein 0.0805 0.4223 1
Onchocerca volvulus Methionine aminopeptidase 2 homolog 0.0053 0.0208 0.0839
Schistosoma mansoni chloride channel protein 0.0014 0.0003 0.0006
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.0008 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0846 0.2854
Brugia malayi Thioredoxin reductase 0.0169 0.083 0.083
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0016 0.001 0.0062
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0239 0.1201 1
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0121 0.0121
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0178 0.0602
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.1327 0.4479
Giardia lamblia Methionine aminopeptidase 0.0053 0.0208 0.0693
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.0008 0.0012
Echinococcus multilocularis sex peptide receptor 0.0015 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0145 0.0703 0.0703
Echinococcus granulosus snurportin 1 0.062 0.3236 0.4634
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0016 0.001 0.0028
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0008 0.0008
Schistosoma mansoni biogenic amine receptor 0.0015 0.0008 0.002
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0008 0.0012
Echinococcus multilocularis neuropeptide s receptor 0.0467 0.2419 0.3464
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.0008 0.002
Onchocerca volvulus 0.008 0.0352 0.1421
Loa Loa (eye worm) hypothetical protein 0.0145 0.0703 0.0703
Brugia malayi DIX domain containing protein 0.0018 0.0023 0.0023
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0008 0.0008
Mycobacterium ulcerans hypothetical protein 0.0145 0.0703 0.356
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Plasmodium falciparum glutathione reductase 0.0169 0.083 0.7369
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0278 0.141 0.541
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0059 0.024 0.1206
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0319 0.1628 0.3854
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0126 0.06 0.0859
Leishmania major hypothetical protein, conserved 0.0016 0.001 0.0062
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0253 0.0362
Echinococcus granulosus hypothetical protein 0.0015 0.0008 0.0012
Onchocerca volvulus 0.0015 0.0008 0.0033
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0018 0.0023 0.0055
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0008 0.002
Echinococcus granulosus g protein coupled receptor 0.0015 0.0008 0.0012
Loa Loa (eye worm) chloride channel 3 0.0014 0.0003 0.0003
Toxoplasma gondii cytochrome p450 superfamily protein 0.0014 0.0003 0.0002
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.0008 0.0008
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0225 0.1125 0.5706
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0178 0.1467
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0016 0.0014 0.002
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0014 0.0003 0.0001
Plasmodium vivax ataxin-2 like protein, putative 0.0075 0.0326 0.2834
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0053 0.0208 0.0701
Echinococcus multilocularis thyroid hormone receptor alpha 0.0136 0.0654 0.0936
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0023 0.0033
Schistosoma mansoni hypothetical protein 0.0132 0.0634 0.1501
Brugia malayi AKH receptor 0.0015 0.0008 0.0008
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.0008 0.0008
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0052 0.0415
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0057 0.0231 0.1908
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.0008 0.0012
Echinococcus multilocularis cAMP responsive element binding protein 3 0.0053 0.0209 0.0299
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0145 0.0703 0.1665
Schistosoma mansoni hypothetical protein 0.062 0.3236 0.7664
Echinococcus granulosus mixed lineage leukemia protein mll 0.0016 0.0014 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) Smad1 0.0025 0.0058 0.0058
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0145 0.0703 0.356
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0846 0.2854
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0016 0.001 0.0062
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Brugia malayi Importin beta-1 subunit 0.0058 0.0237 0.0237
Schistosoma mansoni neuropeptide receptor 0.0015 0.0008 0.002
Schistosoma mansoni neuropeptide receptor 0.0015 0.0008 0.002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.0008 0.002
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0052 0.0253
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0014 0.0003 0.0001
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0059 0.024 0.198
Mycobacterium ulcerans beta-lactamase 0.0145 0.0703 0.356
Brugia malayi bZIP transcription factor family protein 0.0053 0.0209 0.0209
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0008 0.0012
Onchocerca volvulus 0.0478 0.2476 1
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0016 0.001 0.0066
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0929 0.4885 0.5411
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0121 0.0407
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0023 0.0033
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0008 0.002
Trypanosoma cruzi PAB1-binding protein , putative 0.0075 0.0326 0.27
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0016 0.001 0.0034
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0058 0.0058
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0271 0.1366
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0039
Schistosoma mansoni AMP-activated protein kinase gamma regulatory subunit 0.0014 0.0003 0.0006
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.002 0.0032 0.0046
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0016 0.001 0.0014
Trypanosoma cruzi NADH dehydrogenase, putative 0.0016 0.001 0.0062
Toxoplasma gondii exonuclease III APE 0.0057 0.0231 0.1908
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0386 0.1986 0.2199
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0319 0.1628 0.3854
Schistosoma mansoni opsin-like receptor 0.0015 0.0008 0.002
Onchocerca volvulus 0.0145 0.0703 0.2839
Echinococcus granulosus neuropeptide s receptor 0.0467 0.2419 0.3464
Echinococcus granulosus neuropeptide receptor A26 0.0467 0.2419 0.3464
Brugia malayi CBS domain containing protein 0.0014 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0003 0.0002
Echinococcus granulosus orexin receptor type 2 0.0015 0.0008 0.0012
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.0271 0.2243
Brugia malayi jmjC domain containing protein 0.0041 0.0144 0.0144
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0059 0.024 0.198
Echinococcus granulosus dnaJ subfamily B 0.0805 0.4223 0.6046
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0058 0.0083
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0016 0.001 0.0062
Echinococcus multilocularis thioredoxin glutathione reductase 0.017 0.0835 0.1196
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0053 0.0209 0.0209
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0059 0.024 0.198
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0145 0.0703 0.0776
Entamoeba histolytica hypothetical protein 0.0184 0.091 0.307
Trypanosoma cruzi GMP reductase 0.0239 0.1201 1
Echinococcus multilocularis H(+):Cl() exchange transporter 7 0.0014 0.0003 0.0004
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) chloride channel protein 7 0.0014 0.0003 0.0003
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.0008 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Mycobacterium leprae Conserved hypothetical protein 0.0014 0.0003 0.0001
Echinococcus multilocularis cyclic AMP responsive element binding protein 0.0053 0.0209 0.0299
Brugia malayi CLC chloride channel protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.0008 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Echinococcus granulosus H:Cl exchange transporter 7 0.0014 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0031 0.0092 0.0218
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.0008 0.0012
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0157 0.0224
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0057 0.0231 0.078
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0023 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0008 0.002
Mycobacterium tuberculosis Probable reductase 0.0386 0.1986 0.2199
Mycobacterium tuberculosis Probable hydrolase 0.0145 0.0703 0.0776
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0008 0.0012
Onchocerca volvulus 0.0015 0.0008 0.0033
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0008 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Echinococcus granulosus cyclic AMP dependent transcription factor ATF 6 0.0053 0.0209 0.0299
Echinococcus multilocularis neuropeptide receptor 0.0015 0.0008 0.0012
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.0703 0.2373
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0121 0.0173
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.0703 0.5845
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0059 0.024 0.198
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0122 0.0578 0.137
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.0008 0.0008
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0008 0.0012
Schistosoma mansoni jun-related protein 0.0132 0.0634 0.1501
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0059 0.024 0.0343
Schistosoma mansoni myosin xvIII 0.0015 0.0008 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Plasmodium falciparum thioredoxin reductase 0.0059 0.024 0.2113
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0014 0.0003 0.0001
Loa Loa (eye worm) bZIP transcription factor family protein 0.0053 0.0209 0.0209
Schistosoma mansoni transcription factor LCR-F1 0.0184 0.091 0.2154
Brugia malayi Voltage gated chloride channel family protein 0.0014 0.0003 0.0003
Leishmania major cytochrome p450-like protein 0.0014 0.0003 0.0002
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0052 0.0253
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0017 0.0017
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0121 0.0984
Toxoplasma gondii IMP dehydrogenas 0.0239 0.1201 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0059 0.024 0.2113
Echinococcus granulosus regulator of G protein signaling 7 0.0018 0.0023 0.0033
Brugia malayi putative neuropeptide receptor 0.0015 0.0008 0.0008
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0158 0.0535
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0016 0.001 0.0014
Trypanosoma brucei hypothetical protein, conserved 0.0145 0.0703 0.5845
Mycobacterium leprae putative cytochrome p450 0.0014 0.0003 0.0001
Brugia malayi chloride channel protein 7 0.0014 0.0003 0.0003
Brugia malayi neuropeptide F receptor 0.0015 0.0008 0.0008
Schistosoma mansoni amine GPCR 0.0015 0.0008 0.002
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0155 0.1273
Echinococcus granulosus jun protein 0.0151 0.0735 0.1053
Echinococcus multilocularis orexin receptor type 2 0.0015 0.0008 0.0012
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0373 0.0882
Onchocerca volvulus 0.0061 0.0253 0.1021
Schistosoma mansoni glutamate synthase 0.0016 0.001 0.0024
Onchocerca volvulus 0.0015 0.0008 0.0033
Brugia malayi hypothetical protein 0.0015 0.0008 0.0008
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0058 0.0137
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.01 0.0108
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0023
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0043 0.0157 0.0157
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0053 0.0208 0.0701
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0144 0.0341
Mycobacterium leprae Probable lipase LipE 0.0145 0.0703 0.2692
Schistosoma mansoni hypothetical protein 0.0014 0.0003 0.0007
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0121 0.0407
Echinococcus multilocularis smad 0.0025 0.0058 0.0083
Echinococcus multilocularis SNF4:AMP activated protein kinase gamma subunit 0.0014 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Mycobacterium ulcerans esterase/lipase LipP 0.0145 0.0703 0.356
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0016 0.001 0.0014
Echinococcus granulosus neuropeptide receptor 0.0015 0.0008 0.0012
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0239 0.1201 0.2844
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0157 0.0224
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.0225 0.1125 1
Entamoeba histolytica disulphide oxidoreductase, putative 0.0016 0.001 0.0034
Onchocerca volvulus 0.0015 0.0008 0.0033
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0016 0.001 0.0008
Brugia malayi hypothetical protein 0.0015 0.0008 0.0008
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0052 0.0168
Onchocerca volvulus Putative GMP reductase 0.0099 0.0456 0.1843
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0057 0.0231 0.0231
Echinococcus multilocularis GPCR, family 2 0.0017 0.0017 0.0024
Echinococcus multilocularis snurportin 1 0.062 0.3236 0.4634
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0184 0.091 0.307
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0008 0.002
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.0703 0.2373
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0008 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.024 0.198
Plasmodium vivax SET domain protein, putative 0.0061 0.0253 0.2177
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0239 0.1201 0.1719
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0262 0.1327 0.1327
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0059 0.024 0.024
Brugia malayi larval opioid receptor 0.0015 0.0008 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0008 0.002
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0846 0.2854
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0014 0.0003 0.0001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0319 0.1628 0.233
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0059 0.024 0.1206
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0234 0.0336
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0569 0.2963 1
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0059 0.024 0.0263
Schistosoma mansoni netrin receptor unc5 0.0227 0.1139 0.2697
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0014 0.0003 0.0001
Plasmodium vivax glutathione reductase, putative 0.0169 0.083 0.7351
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0714 0.1022
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.0703 0.5845
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0016 0.001 0.0038
Echinococcus multilocularis serotonin receptor 0.0015 0.0008 0.0012
Entamoeba histolytica thioredoxin reductase, putative 0.0016 0.001 0.0034
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.0008 0.0012
Onchocerca volvulus 0.0015 0.0008 0.0033
Schistosoma mansoni cytochrome P450 0.0014 0.0003 0.0007
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1322 0.6981 0.7736
Plasmodium falciparum methionine aminopeptidase 2 0.0053 0.0208 0.1826
Schistosoma mansoni smad1 5 8 and 0.0025 0.0058 0.0137
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.001 0.0034
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0429 0.2216 0.2454
Brugia malayi hypothetical protein 0.0015 0.0008 0.0008
Brugia malayi Smad1 0.0025 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0016 0.001 0.0062
Onchocerca volvulus 0.0015 0.0008 0.0033
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0003 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0895 0.3021
Echinococcus granulosus peregrin 0.0035 0.0111 0.0159
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0714 0.1691
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0155 0.1301
Brugia malayi initiation factor 2-associated protein. 0.0053 0.0208 0.0208
Schistosoma mansoni glutamate synthase 0.0016 0.001 0.0024
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0016 0.001 0.0062
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0099 0.0456 0.0456
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0569 0.2963 1
Entamoeba histolytica hypothetical protein 0.0184 0.091 0.307
Echinococcus multilocularis methionyl aminopeptidase 2 0.0053 0.0208 0.0297
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0053 0.021 0.021
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0016 0.001 0.0062
Echinococcus multilocularis peregrin 0.0035 0.0111 0.0159
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.0008 0.0012
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.0008 0.0012
Plasmodium falciparum phd finger protein, putative 0.0031 0.0092 0.0796
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0386 0.1986 0.2199
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0052 0.0415
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Brugia malayi neuropeptide F receptor 0.0015 0.0008 0.0008
Mycobacterium tuberculosis Conserved protein 0.0145 0.0703 0.0776
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.0008 0.002
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0057 0.0231 0.1162
Toxoplasma gondii histone lysine methyltransferase SET1 0.0113 0.0529 0.4397
Echinococcus granulosus smad 0.0025 0.0058 0.0083
Echinococcus multilocularis serotonin receptor 0.0015 0.0008 0.0012
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.0008 0.0008
Plasmodium vivax methionine aminopeptidase 2, putative 0.0053 0.0208 0.1772
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.0271 0.2243
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.0008 0.0012
Plasmodium vivax thioredoxin reductase, putative 0.0169 0.083 0.7351
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0068 0.016
Plasmodium vivax importin-beta 2, putative 0.0058 0.0237 0.2035
Schistosoma mansoni protein kinase subunit gamma 0.0014 0.0003 0.0006
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0018 0.0023 0.0023
Echinococcus granulosus expressed protein 0.0053 0.0209 0.0299
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0121 0.0407
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.001 0.0034
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0059 0.024 0.1206
Loa Loa (eye worm) MH2 domain-containing protein 0.036 0.1847 0.1847
Onchocerca volvulus Alhambra homolog 0.0031 0.0092 0.0372
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0014 0.0003 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0008 0.0012
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0059 0.024 0.2113
Brugia malayi ORL1-like opioid receptor 0.0015 0.0008 0.0008
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0016 0.001 0.0062
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.0008 0.0012
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.002 0.0032 0.0046
Loa Loa (eye worm) hypothetical protein 0.0145 0.0703 0.0703
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0008 0.0012
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0058 0.0083
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0692 0.0991
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0569 0.2963 1
Schistosoma mansoni amine GPCR 0.0015 0.0008 0.002
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0139 0.047
Trichomonas vaginalis glutathione reductase, putative 0.0059 0.024 0.0809
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Brugia malayi Dopamine receptor protein 1 0.0015 0.0008 0.0008
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0052 0.0191
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.0008 0.0012
Brugia malayi Protein kinase domain containing protein 0.0227 0.1139 0.1139
Onchocerca volvulus 0.0014 0.0003 0.001
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0121 0.0173
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.0125 0.0596 0.228
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.002
Echinococcus granulosus neuropeptide receptor 0.0015 0.0008 0.0012
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0016 0.001 0.0062
Echinococcus granulosus fmrfamide receptor 0.0015 0.0008 0.0012
Trypanosoma cruzi NADH dehydrogenase, putative 0.0016 0.001 0.0062
Loa Loa (eye worm) hypothetical protein 0.0099 0.0453 0.0453
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0053 0.0209 0.0299
Loa Loa (eye worm) hypothetical protein 0.0058 0.0237 0.0237
Onchocerca volvulus 0.0016 0.001 0.004
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0059 0.024 0.198
Brugia malayi Cytochrome P450 family protein 0.0023 0.005 0.005
Trypanosoma brucei PAB1-binding protein , putative 0.0075 0.0326 0.27
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.001 0.0034
Echinococcus multilocularis 5' AMP activated protein kinase subunit gamma 0.0014 0.0003 0.0004
Echinococcus granulosus somatostatin receptor 0.0015 0.0008 0.0012
Leishmania major importin beta-1 subunit, putative 0.0047 0.0178 0.1467
Echinococcus multilocularis microtubule associated protein 2 0.0691 0.3614 0.5175
Trichomonas vaginalis esterase, putative 0.0145 0.0703 0.2373
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0155 0.1273
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0846 0.2854
Onchocerca volvulus 0.0015 0.0008 0.0033
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0016 0.001 0.0038
Echinococcus multilocularis fmrfamide receptor 0.0015 0.0008 0.0012
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0016 0.001 0.0062
Brugia malayi loechrig isoform VII 0.0014 0.0003 0.0003
Mycobacterium ulcerans NADH dehydrogenase 0.0016 0.001 0.0038
Brugia malayi RNA, U transporter 1 0.0165 0.0809 0.0809
Echinococcus granulosus fos transcription factor 0.0053 0.0209 0.0299
Mycobacterium leprae Conserved hypothetical protein 0.0502 0.2604 1
Plasmodium falciparum thioredoxin reductase 0.0169 0.083 0.7369
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0014 0.0003 0.0001
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0016 0.001 0.0028
Schistosoma mansoni amine GPCR 0.0015 0.0008 0.002
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0106 0.0152
Loa Loa (eye worm) initiation factor 2-associated protein 0.0053 0.0208 0.0208
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0239 0.1201 0.1201
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0014 0.0003 0.0001
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.0008 0.002
Brugia malayi Dopamine receptor protein 2 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Schistosoma mansoni amine GPCR 0.0015 0.0008 0.002
Loa Loa (eye worm) cytochrome P450 family protein 0.0023 0.005 0.005
Brugia malayi small heat shock protein 0.0698 0.3649 0.3649
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0052 0.0415
Entamoeba histolytica methionine aminopeptidase, putative 0.0053 0.0208 0.0701
Brugia malayi hypothetical protein 0.0015 0.0008 0.0008
Trichomonas vaginalis penicillin-binding protein, putative 0.0145 0.0703 0.2373
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0016 0.001 0.0062
Brugia malayi beta-lactamase family protein 0.0145 0.0703 0.0703
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0268 0.0268
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0016 0.001 0.0062
Loa Loa (eye worm) hypothetical protein 0.0061 0.0253 0.0253
Schistosoma mansoni regulator of G protein signaling 0.0018 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Echinococcus multilocularis beta LACTamase domain containing family member 0.0145 0.0703 0.1006
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0017 0.0024
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0239 0.1201 0.6091
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0052 0.0253
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0145 0.0703 0.0703
Echinococcus multilocularis expressed protein 0.0053 0.0209 0.0299
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0271 0.1366
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0016 0.001 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.1327 0.4479
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0227 0.1139 0.1139
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0178 0.0602
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0319 0.1628 0.233
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0092 0.0735
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0253 0.0598
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0151 0.0735 0.1053
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0016 0.001 0.0038
Loa Loa (eye worm) bZIP transcription factor family protein 0.0053 0.0209 0.0209
Brugia malayi MH2 domain containing protein 0.0025 0.0058 0.0058
Echinococcus multilocularis regulator of G protein signaling 7 0.0018 0.0023 0.0033
Echinococcus granulosus nuclear factor of activated T cells 5 0.1323 0.6984 1
Brugia malayi hypothetical protein 0.0018 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.002
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0319 0.1628 0.1628
Echinococcus multilocularis somatostatin receptor 0.0015 0.0008 0.0012
Treponema pallidum exodeoxyribonuclease (exoA) 0.0057 0.0231 0.0772
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0057 0.0231 0.2036
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0016 0.001 0.0038
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0085 0.0085
Onchocerca volvulus 0.0015 0.0008 0.0033
Brugia malayi sulfakinin receptor protein 0.0015 0.0008 0.0008
Leishmania major cytochrome p450-like protein 0.0023 0.005 0.0394
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0059 0.024 0.198
Schistosoma mansoni thyroid hormone receptor 0.0136 0.0654 0.1548
Echinococcus granulosus cyclic AMP responsive element binding protein 0.0053 0.0209 0.0299
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.0008 0.002
Trichomonas vaginalis penicillin-binding protein, putative 0.0145 0.0703 0.2373
Schistosoma mansoni hypothetical protein 0.0227 0.1139 0.2697
Treponema pallidum thioredoxin reductase (trxB) 0.0016 0.001 0.0025
Onchocerca volvulus 0.0015 0.0008 0.0033
Brugia malayi MH2 domain containing protein 0.0025 0.0058 0.0058
Echinococcus multilocularis cpg binding protein 0.006 0.0246 0.0352
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0053 0.0208 0.0701
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.0008 0.0012
Brugia malayi MH2 domain containing protein 0.036 0.1847 0.1847
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0145 0.0703 0.0776
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.062 0.3236 0.3236
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0127 0.0181
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0121 0.06
Echinococcus granulosus 5' AMP activated protein kinase subunit gamma 0.0014 0.0003 0.0004
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0569 0.2963 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0155 0.0222
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0016 0.001 0.0028
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0058 0.0083
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0155 0.1273
Brugia malayi Cytochrome P450 family protein 0.0014 0.0003 0.0003
Onchocerca volvulus 0.0015 0.0008 0.0033
Loa Loa (eye worm) transcription factor SMAD2 0.036 0.1847 0.1847
Brugia malayi bZIP transcription factor family protein 0.0053 0.0209 0.0209
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0016 0.001 0.0038
Brugia malayi hypothetical protein 0.0184 0.091 0.091
Schistosoma mansoni cpg binding protein 0.006 0.0246 0.0582
Leishmania major hypothetical protein, conserved 0.0016 0.001 0.0062
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0016 0.001 0.0062
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0239 0.1201 0.1719
Brugia malayi Immunoglobulin I-set domain containing protein 0.0227 0.1139 0.1139
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Plasmodium falciparum importin beta, putative 0.0058 0.0237 0.2088
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Entamoeba histolytica hypothetical protein 0.0184 0.091 0.307
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0016 0.001 0.001
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0253 0.0362
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0059 0.024 0.198
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0016 0.001 0.0038
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0023 0.0023
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0101 0.0467 0.0669
Schistosoma mansoni chloride channel protein 0.0014 0.0003 0.0006
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.0008 0.0012
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0059 0.024 0.1206
Brugia malayi hypothetical protein 0.0015 0.0008 0.0008
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.1705 0.9024 1
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.0703 0.2373
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0113 0.0532 0.2691
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.005 0.0394
Echinococcus granulosus methionyl aminopeptidase 2 0.0053 0.0208 0.0297
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0319 0.1628 0.3854
Trypanosoma cruzi trypanothione reductase, putative 0.0169 0.083 0.6904
Mycobacterium ulcerans monoxygenase 0.0016 0.001 0.0038
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.0008 0.002
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0043 0.0157 0.0157
Loa Loa (eye worm) hypothetical protein 0.0698 0.3649 0.3649
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.0008 0.002
Trypanosoma brucei trypanothione reductase 0.0169 0.083 0.6904
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0121 0.0984
Mycobacterium leprae conserved hypothetical protein 0.0145 0.0703 0.2692
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0319 0.1628 0.1628
Schistosoma mansoni biogenic amine receptor 0.0015 0.0008 0.002
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0825 0.433 0.6199
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0429 0.2216 0.2454
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0016 0.001 0.0038
Echinococcus granulosus geminin 0.0692 0.3622 0.5185
Brugia malayi beta-lactamase 0.0145 0.0703 0.0703
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0053 0.0209 0.0299
Leishmania major guanosine monophosphate reductase 0.0239 0.1201 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Brugia malayi glutathione reductase 0.0169 0.083 0.083
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0023 0.0033
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.021 0.021
Mycobacterium tuberculosis Probable lipase LipD 0.0145 0.0703 0.0776
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.0008 0.0012
Giardia lamblia Thioredoxin reductase 0.0016 0.001 0.0025
Loa Loa (eye worm) hypothetical protein 0.0227 0.1139 0.1139
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0383 0.197 0.7562
Mycobacterium tuberculosis Probable lipase LipE 0.0145 0.0703 0.0776
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0253 0.0598
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0014 0.0003 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0015 0.0008 0.0012
Schistosoma mansoni inositol monophosphatase 0.0036 0.0121 0.0285
Brugia malayi bZIP transcription factor family protein 0.0151 0.0735 0.0735
Echinococcus multilocularis jun protein 0.0151 0.0735 0.1053
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0121 0.0407
Leishmania major hypothetical protein, conserved 0.0075 0.0326 0.27
Chlamydia trachomatis replicative DNA helicase 0.0383 0.197 1
Trichomonas vaginalis set domain proteins, putative 0.0476 0.2466 0.8324
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.0008 0.002
Brugia malayi hypothetical protein 0.0015 0.0008 0.0008
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0278 0.141 0.7154
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.0008 0.0012
Schistosoma mansoni jumonji domain containing protein 0.008 0.0356 0.0844
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Mycobacterium ulcerans lipase LipD 0.0145 0.0703 0.356
Brugia malayi Serotonin receptor 0.0015 0.0008 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0262 0.1327 0.4479
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0059 0.024 0.198
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0017 0.0024
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0126 0.06 0.0859
Trypanosoma brucei methionine aminopeptidase 2, putative 0.0053 0.0208 0.1711
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0059 0.024 0.1206
Onchocerca volvulus 0.0015 0.0008 0.0033
Schistosoma mansoni cpg binding protein 0.0057 0.0229 0.0541
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0014 0.0003 0.0001
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0059 0.024 0.0568
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0016 0.001 0.0066
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0092 0.0092
Schistosoma mansoni dishevelled 0.0018 0.0023 0.0055
Brugia malayi hypothetical protein 0.008 0.0352 0.0352
Schistosoma mansoni hypothetical protein 0.0016 0.001 0.0024
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0053 0.0208 0.1711
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0319 0.1628 0.233
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0014 0.0003 0.0001
Toxoplasma gondii NADPH-glutathione reductase 0.0059 0.024 0.198
Schistosoma mansoni hypothetical protein 0.0034 0.0106 0.0251
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.0271 0.0388
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.0008 0.0012
Plasmodium falciparum ferrodoxin reductase-like protein 0.0016 0.001 0.0066
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.0008 0.0008
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0846 0.2854
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0326 0.2881
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0016 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0016 0.001 0.0008
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0429 0.2216 0.851
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0253 0.0598
Loa Loa (eye worm) hypothetical protein 0.0145 0.0703 0.0703
Echinococcus multilocularis geminin 0.0692 0.3622 0.5185
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0014 0.0003 0.0001
Entamoeba histolytica Ran family GTPase 0.0043 0.0155 0.0524
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0184 0.091 0.1302
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0016 0.001 0.0008
Leishmania major NADH dehydrogenase, putative 0.0016 0.001 0.0062
Loa Loa (eye worm) CXXC zinc finger family protein 0.0057 0.0229 0.0229
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0271 0.0643
Onchocerca volvulus 0.0015 0.0008 0.0033
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0016 0.001 0.0034
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0237 0.1956
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0016 0.001 0.0034
Brugia malayi Death domain containing protein 0.0227 0.1139 0.1139
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0014 0.0003 0.0001
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.0008 0.0012
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0158 0.0535
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Entamoeba histolytica hypothetical protein 0.0023 0.0052 0.0176
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0016 0.001 0.0062
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.0008 0.0012
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0052 0.0055
Mycobacterium tuberculosis Conserved protein 0.0145 0.0703 0.0776
Schistosoma mansoni smad1 5 8 and 0.0025 0.0058 0.0137
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.0008 0.002
Loa Loa (eye worm) DIX domain-containing protein 0.0018 0.0023 0.0023
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0145 0.0703 0.0703
Trypanosoma cruzi GMP reductase 0.0239 0.1201 1
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0014 0.0003 0.0001
Trichomonas vaginalis glutamate synthase, putative 0.0016 0.001 0.0034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.024 0.198
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.0008 0.0012
Onchocerca volvulus 0.0015 0.0008 0.0033
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0059 0.024 0.1206
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Brugia malayi glutamate synthase 0.0016 0.001 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.024 0.198
Schistosoma mansoni hypothetical protein 0.0126 0.06 0.142
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0053 0.0208 0.1711
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0057 0.0231 0.1162
Schistosoma mansoni hypothetical protein 0.0184 0.091 0.2154
Echinococcus granulosus GPCR family 2 0.0017 0.0017 0.0024
Schistosoma mansoni z-protein (S1r protein) 0.0018 0.0023 0.0055
Schistosoma mansoni dishevelled 0.0018 0.0023 0.0055
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.024 0.198
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0016 0.001 0.0034
Chlamydia trachomatis thioredoxin reductase 0.0016 0.001 0.0038
Onchocerca volvulus 0.0018 0.0023 0.0094
Echinococcus granulosus AMP activated protein kinase gamma regulatory 0.0014 0.0003 0.0004
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0169 0.083 0.0917
Echinococcus granulosus sex peptide receptor 0.0015 0.0008 0.0012
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0229 0.1148 0.2719
Mycobacterium tuberculosis Probable oxidoreductase 0.0429 0.2216 0.2454
Echinococcus granulosus g protein coupled receptor 0.0015 0.0008 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0008 0.002
Echinococcus granulosus netrin receptor unc 5 0.0227 0.1139 0.163
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0239 0.1201 0.4606
Brugia malayi ancient conserved domain protein 2 0.0014 0.0003 0.0003
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0057 0.0231 0.1908
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0386 0.1986 0.2199
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0052 0.0415
Loa Loa (eye worm) thioredoxin reductase 0.0169 0.083 0.083
Trichomonas vaginalis ran, putative 0.0043 0.0155 0.0524
Brugia malayi hypothetical protein 0.0075 0.0326 0.0326
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.0008 0.0012
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0018 0.0023 0.0094
Giardia lamblia Fructose-bisphosphate aldolase 0.0569 0.2963 1
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0016 0.001 0.0062
Brugia malayi beta-lactamase family protein 0.0145 0.0703 0.0703
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0145 0.0703 0.0703
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0145 0.0703 0.1665
Leishmania major trypanothione reductase 0.0169 0.083 0.6904
Brugia malayi PHD-finger family protein 0.0031 0.0092 0.0092
Echinococcus multilocularis netrin receptor unc 5 0.0227 0.1139 0.163
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0386 0.1986 0.7626
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.0008 0.0012
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.0271 0.1366
Brugia malayi regulator of G-protein signaling egl-10 0.0018 0.0023 0.0023
Trypanosoma cruzi cytochrome P450, putative 0.0023 0.005 0.0394
Echinococcus granulosus cpg binding protein 0.006 0.0246 0.0352
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.0008 0.0008
Mycobacterium ulcerans glutamate synthase subunit beta 0.0016 0.001 0.0038
Trichomonas vaginalis glutamate synthase, putative 0.0016 0.001 0.0034
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0101 0.0467 0.0669
Echinococcus multilocularis 0.0014 0.0003 0.0004
Schistosoma mansoni thyroid hormone receptor 0.0136 0.0654 0.1548
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0003 0.0002
Leishmania major cytochrome p450-like protein 0.0014 0.0003 0.0002
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0239 0.1201 1
Schistosoma mansoni ap endonuclease 0.0057 0.0231 0.0547
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.0008 0.0012
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0016 0.001 0.001
Toxoplasma gondii LsmAD domain-containing protein 0.0075 0.0326 0.27
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0092 0.0218
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0008 0.002
Schistosoma mansoni importin beta-1 0.0058 0.0237 0.0561
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0239 0.1201 0.1328
Giardia lamblia NADH oxidase lateral transfer candidate 0.0059 0.024 0.0801
Onchocerca volvulus Glucosylceramidase homolog 0.0172 0.0846 0.3416
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.0008 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0895 0.3021
Brugia malayi hypothetical protein 0.0015 0.0008 0.0008
Schistosoma mansoni neuropeptide receptor 0.0015 0.0008 0.002
Trypanosoma brucei NADH dehydrogenase 0.0016 0.001 0.0062
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0059 0.024 0.198
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.0008 0.002
Leishmania major methionine aminopeptidase 2, putative 0.0053 0.0208 0.1711
Loa Loa (eye worm) CYP4Cod1 0.0023 0.005 0.005
Echinococcus multilocularis regulator of G protein signaling 7 0.0018 0.0023 0.0033
Brugia malayi exodeoxyribonuclease III family protein 0.0057 0.0231 0.0231
Loa Loa (eye worm) GMP reductase 0.0099 0.0456 0.0456
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0016 0.001 0.0014
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Loa Loa (eye worm) bZIP transcription factor family protein 0.0053 0.0209 0.0209
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Echinococcus multilocularis cyclic AMP dependent transcription factor ATF 6 0.0053 0.0209 0.0299
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0386 0.1986 0.2199
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0058 0.0083
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0139 0.0461
Schistosoma mansoni amine GPCR 0.0015 0.0008 0.002
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0014 0.0003 0.0001
Onchocerca volvulus Neuropeptide F receptor homolog 0.0015 0.0008 0.0033
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.0008 0.0012
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0184 0.091 0.1302
Brugia malayi Cytochrome P450 family protein 0.0023 0.005 0.005
Echinococcus granulosus glutamate synthase 0.0016 0.001 0.0014
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.0008 0.0008
Echinococcus granulosus H:Cl exchange transporter 3 0.0014 0.0003 0.0004
Brugia malayi Bromodomain containing protein 0.0035 0.0111 0.0111
Echinococcus multilocularis muscleblind protein 1 0.063 0.3287 0.4707
Brugia malayi bZIP transcription factor family protein 0.0053 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0145 0.0703 0.0703
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0373 0.0533
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.0271 0.0298
Echinococcus granulosus thioredoxin glutathione reductase 0.017 0.0835 0.1196
Schistosoma mansoni hypothetical protein 0.0692 0.3622 0.8576
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0016 0.001 0.0028
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0253 0.0362
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0155 0.1273
Echinococcus granulosus g protein coupled receptor 0.0015 0.0008 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0569 0.2963 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0059 0.024 0.2061
Toxoplasma gondii selenide, water dikinase 0.0016 0.001 0.0062
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0158 0.1331
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.0008 0.0012
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0059 0.024 0.198
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0106 0.0152
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0059 0.024 0.198
Loa Loa (eye worm) hypothetical protein 0.0031 0.0092 0.0092
Echinococcus multilocularis glutamate synthase 0.0016 0.001 0.0014
Schistosoma mansoni histamine h1 receptor 0.0015 0.0008 0.002
Leishmania major GTP-binding protein, putative 0.0043 0.0155 0.1273
Treponema pallidum replicative DNA helicase (dnaB) 0.0383 0.197 0.6646
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0016 0.001 0.0025
Echinococcus granulosus allatostatin A receptor 0.0015 0.0008 0.0012
Schistosoma mansoni camp-response element binding protein 0.0053 0.0209 0.0495
Echinococcus granulosus muscleblind protein 0.063 0.3287 0.4707
Onchocerca volvulus 0.0015 0.0008 0.0033
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0016 0.001 0.0008
Schistosoma mansoni sulfide quinone reductase 0.0016 0.001 0.0024
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0016 0.001 0.0034
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0016 0.001 0.0014
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.0225 0.1125 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0052 0.0379
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.0008 0.002
Brugia malayi Pre-SET motif family protein 0.0061 0.0253 0.0253
Schistosoma mansoni inositol monophosphatase 0.0036 0.0121 0.0285
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.0008 0.0012
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0158 0.13
Brugia malayi Muscleblind-like protein 0.063 0.3287 0.3287
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.0008 0.002
Toxoplasma gondii ABC1 family protein 0.0145 0.0703 0.5845
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0023
Brugia malayi GnHR receptor homolog 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0053 0.021 0.021
Onchocerca volvulus 0.0145 0.0703 0.2839
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Mycobacterium ulcerans hypothetical protein 0.0016 0.001 0.0038
Schistosoma mansoni camp-response element binding protein-related 0.0053 0.0209 0.0495
Onchocerca volvulus 0.0145 0.0703 0.2839
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.0008 0.0012
Brugia malayi hypothetical protein 0.0015 0.0008 0.0008
Echinococcus granulosus regulator of G protein signaling 7 0.0018 0.0023 0.0033
Trypanosoma cruzi trypanothione reductase, putative 0.0059 0.024 0.198
Schistosoma mansoni camp-response element binding protein-related 0.0053 0.0209 0.0495
Loa Loa (eye worm) hypothetical protein 0.0014 0.0003 0.0003
Echinococcus multilocularis allatostatin A receptor 0.0015 0.0008 0.0012
Schistosoma mansoni ran 0.0043 0.0155 0.0367
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0039
Onchocerca volvulus 0.0053 0.0209 0.0844
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0014 0.0003 0.0001
Plasmodium falciparum ataxin-2 like protein, putative 0.0075 0.0326 0.2881
Loa Loa (eye worm) cytochrome P450 0.0014 0.0003 0.0003
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.0008 0.0008
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.0271 0.0643
Echinococcus granulosus death domain containing protein 0.0227 0.1139 0.163
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0569 0.2963 1
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0125 0.0596 0.0658
Loa Loa (eye worm) IMP dehydrogenase 1 0.0239 0.1201 0.1201
Brugia malayi RE15519p 0.0015 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Treponema pallidum fructose-bisphosphate aldolase 0.0569 0.2963 1
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0237 0.1956
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0014 0.0003 0.0002
Brugia malayi hypothetical protein 0.0018 0.0023 0.0023
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0016 0.001 0.001
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0227 0.1139 0.163
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.0271 0.0388
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0057 0.0231 0.0772
Loa Loa (eye worm) acetyltransferase 0.0147 0.0714 0.0714
Loa Loa (eye worm) hypothetical protein 0.0367 0.1885 0.1885
Onchocerca volvulus Netrin receptor homolog 0.0227 0.1139 0.46
Schistosoma mansoni ran 0.0043 0.0155 0.0367
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0155 0.1359
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0092 0.0746
Loa Loa (eye worm) hypothetical protein 0.0018 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0017
Loa Loa (eye worm) programmed cell death 8 0.0016 0.001 0.001
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0253 0.2087
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.0008 0.0012
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0155 0.0515
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0016 0.001 0.0034
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0569 0.2963 1
Toxoplasma gondii methionine aminopeptidase 2, putative 0.0053 0.0208 0.1711
Echinococcus granulosus H:Cl exchange transporter 4 0.0014 0.0003 0.0004
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0016 0.001 0.0008
Mycobacterium ulcerans ferredoxin reductase 0.0016 0.001 0.0038
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0016 0.001 0.0062
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0151 0.0735 0.1053
Schistosoma mansoni jumonji/arid domain-containing protein 0.0041 0.0144 0.0341
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0016 0.001 0.0038
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0139 0.1216
Toxoplasma gondii thioredoxin reductase 0.0169 0.083 0.6904
Loa Loa (eye worm) hypothetical protein 0.0084 0.0373 0.0373
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.0008 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0569 0.2963 1
Trichomonas vaginalis ap endonuclease, putative 0.0057 0.0231 0.078
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0373 0.0373
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.0008 0.0008
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0121 0.0984
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0239 0.1201 1
Plasmodium falciparum glutathione reductase 0.0059 0.024 0.2113
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0121 0.0984
Loa Loa (eye worm) hypothetical protein 0.063 0.3287 0.3287
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.021 0.021
Echinococcus granulosus Smad4 0.0025 0.0058 0.0083
Loa Loa (eye worm) jmjC domain-containing protein 0.0041 0.0144 0.0144
Schistosoma mansoni hypothetical protein 0.0036 0.0121 0.0286
Brugia malayi cytochrome P450 0.0014 0.0003 0.0003
Trichomonas vaginalis mercuric reductase, putative 0.0059 0.024 0.0809
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0017 0.0017
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0016 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0015 0.0008 0.002
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0016 0.001 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0846 0.2854
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.0008 0.0012
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0092 0.0132
Loa Loa (eye worm) histone methyltransferase 0.002 0.0032 0.0032
Loa Loa (eye worm) glutathione reductase 0.0169 0.083 0.083
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0057 0.0231 0.0253
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0016 0.0014 0.002
Brugia malayi MH1 domain containing protein 0.0025 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0008
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.0008 0.0012
Toxoplasma gondii hypothetical protein 0.0018 0.0023 0.0173
Trichomonas vaginalis apoptosis inducing factor, putative 0.0016 0.001 0.0034
Brugia malayi Pre-SET motif family protein 0.0418 0.2159 0.2159
Brugia malayi CXXC zinc finger family protein 0.0057 0.0229 0.0229
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0016 0.001 0.0014
Brugia malayi GMP reductase 0.0099 0.0456 0.0456
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0016 0.0014 0.002
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0016 0.001 0.0034
Echinococcus multilocularis dnaJ subfamily B 0.0805 0.4223 0.6046
Mycobacterium tuberculosis Probable dehydrogenase 0.0386 0.1986 0.2199
Loa Loa (eye worm) hypothetical protein 0.0053 0.0209 0.0209

Activities

Activity type Activity value Assay description Source Reference
Activity (binding) = 4 % Inhibition of MetAP2 assessed as remaining enzyme activity at 200 nM after 8 hrs relative to untreated control ChEMBL. 19929003
IC50 (ADMET) = 0.25 nM Antiproliferative activity against HUVEC after 72 hrs by MTT assay ChEMBL. 19929003

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 19929003

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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