Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | sodium/solute symporter | 0.0039 | 0.0594 | 0.0594 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0336 | 0.0336 |
Trypanosoma brucei | polo-like protein kinase | 0.0107 | 0.2605 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0819 | 0.0819 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.1001 | 0.1508 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0107 | 0.2605 | 0.2605 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.2605 | 0.3927 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0594 | 0.0594 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.2605 | 0.3927 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0107 | 0.2605 | 1 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0039 | 0.0594 | 0.0594 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.4582 | 0.4582 |
Brugia malayi | Sodium:solute symporter family protein | 0.0039 | 0.0594 | 0.0594 |
Trichomonas vaginalis | set domain proteins, putative | 0.0242 | 0.6632 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0336 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0107 | 0.2605 | 0.2605 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0053 | 0.1001 | 0.1508 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0336 | 0.0336 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0107 | 0.2605 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0107 | 0.2605 | 0.2605 |
Onchocerca volvulus | 0.0242 | 0.6632 | 1 | |
Echinococcus multilocularis | geminin | 0.0173 | 0.4582 | 0.4582 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0213 | 0.5758 | 0.5758 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0039 | 0.0594 | 0.0594 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0336 | 0.0336 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0819 | 0.0819 |
Echinococcus multilocularis | solute carrier family 5 | 0.0039 | 0.0594 | 0.0594 |
Giardia lamblia | Kinase, PLK | 0.0107 | 0.2605 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.2605 | 0.3927 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0107 | 0.2605 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0819 | 0.0819 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0039 | 0.0594 | 0.0594 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0336 | 0.0336 |
Schistosoma mansoni | kinase | 0.0054 | 0.1042 | 0.1042 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0336 | 0.0336 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.4582 | 0.4582 |
Echinococcus granulosus | solute carrier family 5 | 0.0039 | 0.0594 | 0.0594 |
Onchocerca volvulus | 0.0039 | 0.0594 | 0.041 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0336 | 0.0336 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0039 | 0.0594 | 1 |
Schistosoma mansoni | inositol transporter | 0.0039 | 0.0594 | 0.0594 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0107 | 0.2605 | 0.3603 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.2605 | 0.3927 |
Echinococcus granulosus | sodium:glucose cotransporter | 0.0039 | 0.0594 | 0.0594 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0819 | 0.0819 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0336 | 0.5655 |
Schistosoma mansoni | inositol transporter | 0.0039 | 0.0594 | 0.0594 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0819 | 0.0819 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.2605 | 0.3927 |
Echinococcus granulosus | geminin | 0.0173 | 0.4582 | 0.4582 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0336 | 0.0336 |
Brugia malayi | Pre-SET motif family protein | 0.0213 | 0.5758 | 0.5758 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.2605 | 0.3927 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0107 | 0.2605 | 0.2605 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0819 | 0.0819 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0819 | 0.0819 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0336 | 0.0336 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0336 | 0.0336 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0303 | 0.0303 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0039 | 0.0594 | 0.0594 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0819 | 0.0819 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0107 | 0.2605 | 0.2605 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0819 | 0.0819 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0039 | 0.0594 | 0.0594 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0107 | 0.2605 | 0.3927 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0039 | 0.0594 | 0.0594 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0107 | 0.2605 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.