Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.8833 | 1 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0101 | 0.5707 | 0.5707 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.6814 | 0.7715 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.6814 | 0.7715 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5707 | 0.6461 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0821 | 0.093 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.3399 | 0.3848 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.3399 | 0.3399 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0101 | 0.5707 | 0.5707 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.3399 | 0.3399 |
Schistosoma mansoni | amidase | 0.0101 | 0.5707 | 0.5707 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.3399 | 0.3399 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0821 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.3399 | 0.3399 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0821 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0101 | 0.5707 | 0.5707 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0821 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.3399 | 0.3399 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0821 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0821 | 0.093 |
Brugia malayi | amidase | 0.0101 | 0.5707 | 0.6461 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.3399 | 0.3848 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.6814 | 0.7715 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0821 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0821 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.3399 | 0.3399 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.3399 | 0.3848 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.3399 | 0.3848 |
Onchocerca volvulus | 0.0149 | 0.8833 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0016 | 0.0253 | 0.0286 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.3399 | 0.3848 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0101 | 0.5707 | 0.5707 |
Brugia malayi | hypothetical protein | 0.0149 | 0.8833 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0821 | 1 |
Brugia malayi | RNA binding protein | 0.0065 | 0.3399 | 0.3848 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0101 | 0.5707 | 0.5707 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0821 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.3399 | 0.3399 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | 18844422 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.