Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine proteinase, putative | 0.0032 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0032 | 0.3182 | 0.3182 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0032 | 0.3182 | 0.3182 |
Brugia malayi | cathepsin L-like precursor | 0.0032 | 0.3182 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0032 | 0.3182 | 0.3182 |
Echinococcus granulosus | cathepsin l1 | 0.0032 | 0.3182 | 0.3182 |
Brugia malayi | Cathepsin L-like precursor | 0.0032 | 0.3182 | 0.3182 |
Brugia malayi | Cathepsin L-like precursor | 0.0032 | 0.3182 | 0.3182 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0032 | 0.3182 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0032 | 0.3182 | 0.3182 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 50 ug ml-1 | Antibacterial activity against Escherichia coli ATCC 8739 by turbidity method | ChEMBL. | 19713009 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.