Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | MET proto-oncogene, receptor tyrosine kinase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.009 | 0.0259 | 1 |
Onchocerca volvulus | 0.0032 | 0.0055 | 0.0493 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.007 | 0.0217 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0027 | 0.0035 | 0.0365 |
Schistosoma mansoni | smad1 5 8 and | 0.0059 | 0.015 | 0.015 |
Schistosoma mansoni | hypothetical protein | 0.0103 | 0.0307 | 0.0307 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.003 | 0.0047 | 0.0033 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0112 | 0.1238 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.007 | 0.0749 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0338 | 0.114 | 0.3757 |
Schistosoma mansoni | hypothetical protein | 0.0304 | 0.102 | 0.102 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0037 | 0.1776 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0014 | 0.0029 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.0934 | 0.3075 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0338 | 0.114 | 0.3761 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0026 | 0.0034 | 0.002 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0027 | 0.0035 | 0.4057 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0011 | 0.0021 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.009 | 0.0259 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0027 | 0.0035 | 0.0365 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0177 | 0.2004 |
Brugia malayi | nuclear receptor NHR-88 | 0.0021 | 0.0014 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.007 | 0.0217 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0026 | 0.0034 | 0.002 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.007 | 0.0825 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.041 | 0.1394 | 0.4602 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0034 | 0.0096 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0072 | 0.0194 | 0.7306 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.009 | 0.0259 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0014 | 0.0036 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0507 | 0.1739 | 0.1728 |
Loa Loa (eye worm) | hypothetical protein | 0.0507 | 0.1739 | 0.5738 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0037 | 0.0818 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0055 | 0.0055 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0011 | 0.0021 |
Loa Loa (eye worm) | nuclear factor I | 0.0033 | 0.0056 | 0.017 |
Giardia lamblia | GTOR | 0.009 | 0.0259 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0035 | 0.0101 |
Schistosoma mansoni | smad | 0.0059 | 0.015 | 0.015 |
Loa Loa (eye worm) | TAR-binding protein | 0.0338 | 0.114 | 0.3757 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0021 | 0.0014 | 0.0036 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0053 | 0.0128 | 0.1432 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.007 | 0.0217 |
Brugia malayi | Plexin repeat family protein | 0.0021 | 0.0014 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.0029 |
Echinococcus granulosus | dna polymerase eta | 0.0022 | 0.0017 | 0.0004 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0.0014 | 0.0014 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.003 | 0.0047 | 0.1214 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.007 | 0.0749 |
Schistosoma mansoni | hypothetical protein | 0.0259 | 0.0859 | 0.0859 |
Onchocerca volvulus | 0.0037 | 0.007 | 0.0676 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.009 | 0.0259 | 0.2968 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.041 | 0.1394 | 0.4602 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.003 | 0.0047 | 0.1214 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0047 | 0.0469 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0035 | 0.0108 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0021 | 0.0014 | 0.0036 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0014 | 0.0036 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.04 | 0.04 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0055 | 0.0055 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0022 | 0.0017 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.0029 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.028 | 0.0933 | 0.0921 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0035 | 0.4057 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0059 | 0.015 | 0.0481 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0304 | 0.102 | 0.102 |
Schistosoma mansoni | survival motor neuron protein | 0.0103 | 0.0307 | 0.0307 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.009 | 0.0259 | 0.2968 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0035 | 0.0736 |
Brugia malayi | Pre-SET motif family protein | 0.0227 | 0.0744 | 0.245 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.009 | 0.0259 | 0.2405 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0304 | 0.102 | 0.1008 |
Brugia malayi | MH2 domain containing protein | 0.087 | 0.3027 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.041 | 0.1394 | 0.4598 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0035 | 0.0108 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.009 | 0.0259 | 0.0245 |
Schistosoma mansoni | tar DNA-binding protein | 0.0338 | 0.114 | 0.114 |
Brugia malayi | MH1 domain containing protein | 0.0059 | 0.015 | 0.0488 |
Onchocerca volvulus | 0.0103 | 0.0307 | 0.3485 | |
Loa Loa (eye worm) | RNA binding protein | 0.0338 | 0.114 | 0.3757 |
Echinococcus granulosus | dna polymerase kappa | 0.0022 | 0.0017 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.041 | 0.1394 | 0.4598 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.0017 | 0.1072 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0027 | 0.0035 | 0.4057 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0.0014 | 0.0014 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.087 | 0.3027 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.028 | 0.0933 | 0.0933 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0153 | 0.0482 | 0.0482 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0.0014 | 0.0014 |
Echinococcus multilocularis | smad | 0.0059 | 0.015 | 0.0137 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0177 | 0.2004 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0177 | 0.2004 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0014 | 0.0036 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0077 | 0.0212 | 0.2418 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0071 | 0.0193 | 0.2199 |
Echinococcus granulosus | smad | 0.0059 | 0.015 | 0.0137 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0022 | 0.0017 | 0.0049 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0022 | 0.0017 | 0.0123 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.007 | 1 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.009 | 0.0259 | 1 |
Schistosoma mansoni | Smad4 | 0.0026 | 0.0034 | 0.0034 |
Echinococcus multilocularis | plexin a4 | 0.0025 | 0.0027 | 0.0014 |
Schistosoma mansoni | tar DNA-binding protein | 0.0338 | 0.114 | 0.114 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.0029 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0037 | 0.0114 |
Schistosoma mansoni | tar DNA-binding protein | 0.0338 | 0.114 | 0.114 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0026 | 0.0034 | 0.002 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.007 | 1 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.009 | 0.0259 | 0.0259 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.007 | 0.0224 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0037 | 0.0818 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.003 | 0.0047 | 0.1214 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0235 | 0.0775 | 1 |
Echinococcus multilocularis | dna polymerase eta | 0.0022 | 0.0017 | 0.0004 |
Schistosoma mansoni | plexin | 0.0021 | 0.0014 | 0.0014 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0048 | 0.0112 | 0.1235 |
Schistosoma mansoni | smad1 5 8 and | 0.0059 | 0.015 | 0.015 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.007 | 0.22 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0022 | 0.0017 | 0.1072 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0048 | 0.0112 | 0.1235 |
Brugia malayi | steroid hormone receptor | 0.0021 | 0.0014 | 0.0036 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0037 | 1 |
Brugia malayi | hypothetical protein | 0.0507 | 0.1739 | 0.5741 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0058 | 0.0147 | 0.1649 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.04 | 0.04 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0017 | 0.0042 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.007 | 0.0825 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0022 | 0.0017 | 0.0017 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.003 | 0.0047 | 0.0146 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0022 | 0.0017 | 0.0123 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0055 | 0.0173 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0014 | 0.0036 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.007 | 0.0825 |
Schistosoma mansoni | hypothetical protein | 0.028 | 0.0934 | 0.0934 |
Brugia malayi | MH2 domain containing protein | 0.0059 | 0.015 | 0.0488 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.007 | 0.22 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0.0014 | 0.0014 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0021 | 0.0014 | 0.0036 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0022 | 0.0017 | 0.0004 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0014 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0056 | 0.017 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0042 | 0.009 | 0.3032 |
Entamoeba histolytica | hypothetical protein | 0.0304 | 0.102 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0021 | 0.0014 | 0.0029 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.0035 | 0.0177 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0112 | 0.1238 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.0029 |
Onchocerca volvulus | 0.0037 | 0.007 | 0.0676 | |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0014 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.0029 |
Entamoeba histolytica | hypothetical protein | 0.0304 | 0.102 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0059 | 0.015 | 0.0137 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0177 | 0.2004 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0259 | 0.0859 | 0.0847 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0026 | 0.0034 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.007 | 0.0217 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0.0014 | 0.0014 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.009 | 0.0259 | 0.0846 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.009 | 0.0259 | 0.0245 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0021 | 0.0014 | 0.0036 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.007 | 0.22 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.003 |
Brugia malayi | beta-lactamase | 0.0037 | 0.007 | 0.0224 |
Brugia malayi | MH1 domain containing protein | 0.0059 | 0.015 | 0.0488 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0047 | 0.0469 |
Trichomonas vaginalis | set domain proteins, putative | 0.0258 | 0.0855 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.007 | 0.0057 |
Echinococcus multilocularis | tumor protein p63 | 0.1044 | 0.3643 | 0.3635 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0022 | 0.0017 | 0.0049 |
Brugia malayi | Latrophilin receptor protein 2 | 0.013 | 0.04 | 0.1314 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.009 | 0.0259 | 0.2968 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0059 | 0.015 | 0.0137 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.007 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.003 | 0.0047 | 0.1214 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0055 | 0.2832 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.0029 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0021 | 0.0014 | 0.0029 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.007 | 0.0749 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0055 | 0.0055 |
Brugia malayi | nuclear hormone receptor | 0.0021 | 0.0014 | 0.0036 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0047 | 0.0469 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0037 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0055 | 0.0042 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0025 | 0.0216 |
Echinococcus multilocularis | Smad4 | 0.0059 | 0.015 | 0.0137 |
Brugia malayi | Smad1 | 0.0059 | 0.015 | 0.0488 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0026 | 0.0034 | 0.024 |
Echinococcus multilocularis | tar DNA binding protein | 0.0338 | 0.114 | 0.1128 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0014 | 0.0036 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0059 | 0.015 | 0.0481 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.04 | 0.1308 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.007 | 0.0825 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0026 | 0.0034 | 0.0096 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0048 | 0.0112 | 0.1235 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0022 | 0.0017 | 0.0134 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.009 | 0.0259 | 0.084 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0037 | 0.0818 |
Schistosoma mansoni | smad | 0.0026 | 0.0034 | 0.0034 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.013 | 0.04 | 0.1308 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0035 | 0.0736 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.003 | 0.0047 | 0.0033 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0021 | 0.0014 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0011 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.007 | 0.0217 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.007 | 0.0217 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0507 | 0.1739 | 0.1728 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.087 | 0.3027 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0037 | 0.0107 |
Echinococcus granulosus | plexin a4 | 0.0025 | 0.0027 | 0.0014 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.0011 | 0.5 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0026 | 0.0034 | 0.002 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0071 | 0.0193 | 0.2199 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0055 | 0.0055 |
Loa Loa (eye worm) | Smad1 | 0.0059 | 0.015 | 0.0481 |
Brugia malayi | MH2 domain containing protein | 0.0059 | 0.015 | 0.0488 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0035 | 0.0101 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0026 | 0.0034 | 0.0096 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0227 | 0.0744 | 0.2445 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.007 | 0.0217 |
Onchocerca volvulus | 0.0037 | 0.007 | 0.0676 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0071 | 0.0193 | 0.2199 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.007 | 0.0825 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.013 | 0.1455 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0035 | 0.4057 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0037 | 0.0072 | 0.2271 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0011 | 0.0021 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.007 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.007 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0035 | 0.4057 |
Brugia malayi | hypothetical protein | 0.0304 | 0.102 | 0.3364 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.007 | 0.0825 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.009 | 0.0259 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.013 | 0.04 | 0.0387 |
Brugia malayi | TAR-binding protein | 0.0338 | 0.114 | 0.3761 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.007 | 0.007 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.009 | 0.0259 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.007 | 0.0825 |
Echinococcus multilocularis | GPCR, family 2 | 0.013 | 0.04 | 0.0387 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0304 | 0.102 | 0.1008 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0037 | 0.0818 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.007 | 0.0825 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0035 | 0.0101 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0059 | 0.015 | 0.0137 |
Schistosoma mansoni | smad1 5 8 and | 0.0059 | 0.015 | 0.015 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.013 | 0.04 | 0.0387 |
Brugia malayi | MH2 domain containing protein | 0.0026 | 0.0034 | 0.0103 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0022 | 0.0017 | 0.0004 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.028 | 0.0934 | 0.308 |
Schistosoma mansoni | DNA polymerase eta | 0.0022 | 0.0017 | 0.0017 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.007 | 0.0749 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.013 | 0.04 | 0.1314 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | plexin A | 0.0025 | 0.0027 | 0.0075 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.007 | 0.0057 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.003 | 0.0047 | 0.0047 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0071 | 0.0193 | 0.2199 |
Echinococcus granulosus | Smad4 | 0.0059 | 0.015 | 0.0137 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.0035 | 0.0177 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0014 | 0.0029 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.007 | 0.0224 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0047 | 0.0469 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0177 | 0.2004 |
Echinococcus granulosus | tumor protein p63 | 0.1044 | 0.3643 | 0.3635 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.013 | 0.1455 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.007 | 0.0224 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.009 | 0.0259 | 0.2405 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.007 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.028 | 0.0933 | 0.0933 |
Onchocerca volvulus | 0.0258 | 0.0855 | 1 | |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0035 | 0.0736 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0053 | 0.0128 | 0.1432 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.013 | 0.04 | 0.0387 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.007 | 0.0825 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0103 | 0.0307 | 0.1005 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0067 | 0.0177 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0021 | 0.0014 | 0.0036 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0037 | 0.439 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0055 | 0.0042 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.013 | 0.04 | 0.0387 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0021 | 0.0014 | 0.0036 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0072 | 0.0194 | 0.7306 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0059 | 0.015 | 0.0137 |
Entamoeba histolytica | hypothetical protein | 0.0304 | 0.102 | 1 |
Onchocerca volvulus | 0.0021 | 0.0014 | 0.0002 | |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.003 | 0.0047 | 0.1214 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0021 | 0.0014 | 0.0029 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0021 | 0.0014 | 0.0029 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.007 | 0.0749 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0059 | 0.015 | 0.015 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.003 | 0.0047 | 0.0139 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.0011 | 0.0051 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.007 | 1 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0022 | 0.0017 | 0.0017 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.007 | 0.3738 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.007 | 1 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0055 | 0.7408 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.0029 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0047 | 0.0469 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0021 | 0.0014 | 0.0036 |
Echinococcus granulosus | tar DNA binding protein | 0.0338 | 0.114 | 0.1128 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0021 | 0.0014 | 0.0036 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.007 | 0.0825 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0035 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.0482 | 0.1579 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.007 | 0.0749 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.007 | 0.22 |
Onchocerca volvulus | 0.0027 | 0.0035 | 0.0256 | |
Entamoeba histolytica | hypothetical protein | 0.0304 | 0.102 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0027 | 0.0035 | 0.4057 |
Echinococcus multilocularis | dna polymerase kappa | 0.0022 | 0.0017 | 0.0004 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0027 | 0.0035 | 0.0177 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.0051 | 0.0037 |
Schistosoma mansoni | tar DNA-binding protein | 0.0338 | 0.114 | 0.114 |
Brugia malayi | MH1 domain containing protein | 0.0033 | 0.0056 | 0.0177 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.04 | 0.04 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0054 | 0.013 | 0.1455 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0072 | 0.0194 | 0.7306 |
Brugia malayi | MH1 domain containing protein | 0.0033 | 0.0056 | 0.0177 |
Schistosoma mansoni | Smad4 | 0.0059 | 0.015 | 0.015 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0112 | 0.1238 |
Onchocerca volvulus | 0.0153 | 0.0482 | 0.5567 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0.0014 | 0.0014 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.013 | 0.04 | 0.0387 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0071 | 0.0193 | 0.2199 |
Brugia malayi | RNA binding protein | 0.0338 | 0.114 | 0.3761 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0055 | 0.0042 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0027 | 0.0035 | 0.4057 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0259 | 0.0859 | 0.0847 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0177 | 0.2004 |
Brugia malayi | ecdysteroid receptor | 0.0021 | 0.0014 | 0.0036 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0021 | 0.0014 | 0.0036 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.003 | 0.0047 | 0.1214 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0049 | 0.0112 | 0.1238 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0021 | 0.0014 | 0.0029 |
Schistosoma mansoni | tar DNA-binding protein | 0.0338 | 0.114 | 0.114 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0022 | 0.0017 | 0.0042 |
Schistosoma mansoni | Smad4 | 0.0026 | 0.0034 | 0.0034 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.0035 | 0.4057 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.007 | 0.007 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.006 | 0.0154 | 0.173 |
Schistosoma mansoni | hypothetical protein | 0.013 | 0.04 | 0.04 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0067 | 0.0177 | 0.2004 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0011 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.007 | 0.0217 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0014 | 0.0029 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0055 | 0.0167 |
Brugia malayi | plexin A | 0.0025 | 0.0027 | 0.0082 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.