Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.2346 | 0.5411 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0025 | 0.0168 | 0.0412 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0049 | 0.0453 | 0.1108 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.016 | 0.1341 |
Schistosoma mansoni | hypothetical protein | 0.0208 | 0.2346 | 0.5733 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0168 | 0.0389 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0168 | 0.0389 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0096 | 0.1007 | 1 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0055 | 0.0517 | 0.1802 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.009 | 0.0937 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0096 | 0.1013 | 0.2336 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0861 | 0.1986 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0168 | 0.0412 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.016 | 0.037 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0083 | 0.0861 | 0.0861 |
Treponema pallidum | heat shock protein 90 | 0.009 | 0.0937 | 1 |
Brugia malayi | Smad1 | 0.0025 | 0.0168 | 0.0389 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0085 | 0.0208 |
Trichomonas vaginalis | heat shock protein, putative | 0.0056 | 0.0528 | 0.5106 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0314 | 0.2913 |
Schistosoma mansoni | endoplasmin | 0.0096 | 0.1007 | 0.2461 |
Onchocerca volvulus | 0.0025 | 0.016 | 0.074 | |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0025 | 0.0168 | 0.0412 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0314 | 0.0724 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.016 | 0.1341 |
Echinococcus multilocularis | GPCR, family 2 | 0.0096 | 0.1013 | 0.1013 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0049 | 0.0453 | 0.0453 |
Echinococcus multilocularis | geminin | 0.0354 | 0.4092 | 0.4092 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0064 | 0.0623 | 0.6077 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0014 | 0.0029 | 0.0067 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0029 | 0.0207 | 0.1965 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0599 | 0.1463 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0049 | 0.0453 | 0.1046 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0083 | 0.0861 | 0.1996 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0064 | 0.0623 | 0.2878 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0025 | 0.016 | 0.1341 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 0.0599 | 0.1381 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0029 | 0.0207 | 0.0428 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0314 | 0.0724 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0168 | 0.0412 |
Trypanosoma brucei | heat shock protein, putative | 0.0096 | 0.1007 | 1 |
Loa Loa (eye worm) | endoplasmin | 0.0096 | 0.1007 | 0.2323 |
Trichomonas vaginalis | heat shock protein, putative | 0.0082 | 0.0842 | 0.8311 |
Brugia malayi | Probable DNA topoisomerase II | 0.0014 | 0.0029 | 0.0067 |
Trypanosoma brucei | heat shock protein, putative | 0.0096 | 0.1007 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0029 | 0.0067 |
Trypanosoma cruzi | heat shock protein, putative | 0.0064 | 0.0623 | 0.6077 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0055 | 0.0517 | 0.1802 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.016 | 0.037 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0073 | 0.0163 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0314 | 0.2913 |
Trichomonas vaginalis | heat shock protein, putative | 0.0096 | 0.1007 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0599 | 0.1463 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0032 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0029 | 0.0067 |
Echinococcus granulosus | smad | 0.0025 | 0.0168 | 0.0412 |
Echinococcus granulosus | Pyruvate dehydrogenase lipoamide kinase | 0.0014 | 0.0029 | 0.0071 |
Trichomonas vaginalis | endoplasmin, putative | 0.0069 | 0.0694 | 0.6795 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0049 | 0.0453 | 0.1108 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0083 | 0.0861 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0168 | 0.0389 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0096 | 0.1007 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Plasmodium vivax | heat shock protein 90, putative | 0.0064 | 0.0623 | 0.1426 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0314 | 0.2913 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.1013 | 0.2475 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0374 | 0.4335 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0394 | 0.0964 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0394 | 0.0964 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0014 | 0.0029 | 0.0029 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0049 | 0.0453 | 0.1046 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0096 | 0.1007 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0085 | 0.0676 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0049 | 0.0453 | 0.1108 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0014 | 0.0029 | 0.0134 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.016 | 0.1445 |
Plasmodium vivax | heat shock protein 86, putative | 0.0096 | 0.1007 | 0.2347 |
Giardia lamblia | Grp94/Hsp90 | 0.009 | 0.0937 | 0.9282 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0314 | 0.0766 |
Schistosoma mansoni | DNA topoisomerase II | 0.0014 | 0.0029 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.2166 | 0.4996 |
Plasmodium vivax | endoplasmin, putative | 0.0096 | 0.1007 | 0.2347 |
Echinococcus multilocularis | Smad4 | 0.0025 | 0.0168 | 0.0168 |
Toxoplasma gondii | hypothetical protein | 0.0029 | 0.0207 | 0.0428 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0096 | 0.1013 | 0.2475 |
Entamoeba histolytica | 90 kDa heat shock protein, putative | 0.0064 | 0.0623 | 0.6077 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0049 | 0.0453 | 0.1046 |
Brugia malayi | heat shock protein 90 | 0.0096 | 0.1007 | 0.2323 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0314 | 0.2909 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0056 | 0.0528 | 0.1198 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.016 | 0.1445 |
Brugia malayi | Probable ClpP-like protease | 0.0083 | 0.0861 | 0.1986 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0314 | 0.3138 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0096 | 0.1007 | 0.2323 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0192 | 0.2166 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0394 | 0.091 |
Schistosoma mansoni | pyruvate dehydrogenase | 0.0014 | 0.0029 | 0.0071 |
Schistosoma mansoni | heat shock protein | 0.0064 | 0.0623 | 0.1523 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0314 | 0.0767 |
Plasmodium falciparum | heat shock protein 90 | 0.0096 | 0.1007 | 0.2347 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0083 | 0.0861 | 0.9163 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0314 | 0.1051 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0314 | 0.0724 |
Echinococcus granulosus | geminin | 0.0354 | 0.4092 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0354 | 0.4092 | 1 |
Schistosoma mansoni | Smad4 | 0.0025 | 0.0168 | 0.0412 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0096 | 0.1007 | 1 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.009 | 0.0937 | 0.335 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.016 | 0.1445 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0599 | 0.1463 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.0085 | 0.0135 |
Echinococcus multilocularis | smad | 0.0025 | 0.0168 | 0.0168 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0394 | 0.0964 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0304 | 0.3495 | 0.8061 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0025 | 0.0168 | 0.0168 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0083 | 0.0861 | 0.2104 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0096 | 0.1013 | 0.1013 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0096 | 0.1007 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0096 | 0.1007 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0314 | 0.2913 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0083 | 0.0861 | 1 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0096 | 0.1007 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0032 | 0.0075 |
Schistosoma mansoni | heat shock protein | 0.0096 | 0.1007 | 0.2461 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0314 | 0.2913 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0085 | 0.0197 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0073 | 0.0163 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0096 | 0.1013 | 0.2336 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0314 | 0.0724 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.016 | 0.1341 |
Loa Loa (eye worm) | hypothetical protein | 0.0304 | 0.3495 | 0.8061 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0314 | 0.2913 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0314 | 0.1051 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0029 | 0.0207 | 0.0428 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0049 | 0.0453 | 0.1108 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.1013 | 0.2475 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0055 | 0.0517 | 0.0517 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0096 | 0.1007 | 1 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0014 | 0.0029 | 0.0029 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.016 | 0.1445 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0314 | 0.2913 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0073 | 0.0163 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.1013 | 0.2475 |
Trypanosoma brucei | heat shock protein, putative | 0.0096 | 0.1007 | 1 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0082 | 0.0842 | 0.2058 |
Plasmodium vivax | heat shock protein, putative | 0.0362 | 0.4197 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0314 | 0.0766 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0014 | 0.0029 | 0.0067 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0304 | 0.3495 | 0.8061 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.016 | 0.037 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0025 | 0.016 | 0.1445 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0304 | 0.3495 | 0.8061 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0208 | 0.2346 | 0.5411 |
Plasmodium falciparum | endoplasmin, putative | 0.0069 | 0.0694 | 0.1595 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0314 | 0.0723 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0096 | 0.1007 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0374 | 0.4335 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0354 | 0.4092 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0394 | 0.0964 |
Echinococcus multilocularis | heat shock protein | 0.0096 | 0.1007 | 0.1007 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Brugia malayi | RNA binding protein | 0.0061 | 0.0599 | 0.1381 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0096 | 0.1007 | 0.2347 |
Schistosoma mansoni | endoplasmin | 0.0096 | 0.1007 | 0.2461 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0314 | 0.2913 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0064 | 0.0623 | 0.0623 |
Brugia malayi | MH2 domain containing protein | 0.0374 | 0.4335 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0314 | 0.0724 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0064 | 0.0623 | 0.1523 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.1013 | 0.2336 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0314 | 0.1051 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 0.0599 | 0.1381 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0083 | 0.0861 | 0.1996 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0314 | 0.2909 |
Echinococcus granulosus | endoplasmin | 0.009 | 0.0937 | 0.229 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0083 | 0.0861 | 0.9163 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0314 | 0.2909 |
Brugia malayi | kinase, mitochondrial precursor | 0.0014 | 0.0029 | 0.0067 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0049 | 0.0453 | 0.1018 |
Onchocerca volvulus | 0.0038 | 0.0314 | 0.1449 | |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0049 | 0.0453 | 0.4337 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0314 | 0.1051 |
Onchocerca volvulus | 0.0038 | 0.0314 | 0.1449 | |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.016 | 0.037 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0049 | 0.0453 | 0.4337 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0083 | 0.0861 | 0.9163 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0038 | 0.0314 | 0.3138 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0314 | 0.0724 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.0085 | 0.0135 |
Echinococcus multilocularis | Pyruvate dehydrogenase (lipoamide) kinase | 0.0014 | 0.0029 | 0.0029 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0083 | 0.0861 | 0.9163 |
Mycobacterium ulcerans | heat shock protein 90 | 0.009 | 0.0937 | 1 |
Brugia malayi | Endoplasmin precursor | 0.0096 | 0.1007 | 0.2323 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0085 | 0.0197 |
Trypanosoma brucei | heat shock protein, putative | 0.0096 | 0.1007 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0085 | 0.0197 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.009 | 0.0937 | 0.9282 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0085 | 0.0197 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0314 | 0.1051 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0029 | 0.0207 | 0.1965 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0096 | 0.1013 | 0.2475 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0314 | 0.1051 |
Trichomonas vaginalis | heat shock protein, putative | 0.009 | 0.0937 | 0.9282 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0314 | 0.0767 |
Trypanosoma brucei | heat shock protein, putative | 0.0096 | 0.1007 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Echinococcus multilocularis | heat shock protein 90 | 0.0096 | 0.1007 | 0.1007 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0038 | 0.0314 | 0.3138 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0064 | 0.0623 | 0.1426 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.0082 | 0.0842 | 0.2058 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0064 | 0.0623 | 0.1438 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0314 | 0.0724 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.016 | 0.1341 |
Mycobacterium ulcerans | lipase LipD | 0.0038 | 0.0314 | 0.3138 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.024 | 0.2739 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0314 | 0.1051 |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 0.0599 | 0.1463 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0314 | 0.0724 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0096 | 0.1007 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0314 | 0.0684 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.016 | 0.1445 |
Trypanosoma brucei | heat shock protein, putative | 0.0096 | 0.1007 | 1 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0049 | 0.0453 | 0.4337 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0018 | 0.0073 | 0.0163 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0096 | 0.1013 | 0.2336 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0019 | 0.0085 | 0.062 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 0.0599 | 0.1381 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0314 | 0.0314 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0025 | 0.0168 | 0.0389 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0314 | 0.1051 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0394 | 0.091 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0014 | 0.0029 | 0.0134 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0014 | 0.0029 | 0.0067 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0083 | 0.0861 | 0.1996 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.009 | 0.0937 | 0.9282 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0314 | 0.0767 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0394 | 0.0964 |
Brugia malayi | Hsp90 protein | 0.0064 | 0.0623 | 0.1438 |
Loa Loa (eye worm) | nuclear factor I | 0.0014 | 0.0032 | 0.0075 |
Echinococcus granulosus | heat shock protein 90 | 0.0096 | 0.1007 | 0.2461 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0025 | 0.0168 | 0.0168 |
Echinococcus granulosus | Smad4 | 0.0025 | 0.0168 | 0.0412 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0314 | 0.2913 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0096 | 0.1007 | 0.2347 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0083 | 0.0861 | 0.1996 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0168 | 0.0412 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0083 | 0.0861 | 0.9163 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0599 | 0.1463 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.016 | 0.0484 |
Brugia malayi | TAR-binding protein | 0.0061 | 0.0599 | 0.1381 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0168 | 0.0389 |
Echinococcus granulosus | GPCR family 2 | 0.0096 | 0.1013 | 0.2475 |
Mycobacterium ulcerans | beta-lactamase | 0.0038 | 0.0314 | 0.3138 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0082 | 0.0842 | 0.8311 |
Loa Loa (eye worm) | Smad1 | 0.0025 | 0.0168 | 0.0389 |
Echinococcus multilocularis | heat shock protein 90 | 0.0082 | 0.0842 | 0.0842 |
Schistosoma mansoni | smad | 0.0025 | 0.0168 | 0.0412 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0314 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0085 | 0.0197 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0314 | 0.0724 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0314 | 0.1051 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0049 | 0.0453 | 0.4337 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0032 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0029 | 0.0067 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0314 | 0.1051 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.004 | 0.0343 | 0.3205 |
Onchocerca volvulus | 0.0038 | 0.0314 | 0.1449 | |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0083 | 0.0861 | 0.2104 |
Trichomonas vaginalis | heat shock protein, putative | 0.0069 | 0.0694 | 0.6795 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.016 | 0.1445 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.016 | 0.0484 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.009 | 0.0937 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0314 | 0.0724 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0362 | 0.4197 | 1 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0362 | 0.4197 | 1 |
Trichomonas vaginalis | chaperonin, putative | 0.0049 | 0.0453 | 0.4337 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0049 | 0.0453 | 0.4337 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0014 | 0.0029 | 0.0134 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0314 | 0.0724 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.016 | 0.1445 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.016 | 0.037 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0314 | 0.0684 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.016 | 0.1445 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0394 | 0.0394 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0096 | 0.1013 | 0.1013 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Brugia malayi | N-terminal motif family protein | 0.0192 | 0.2166 | 0.4996 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0394 | 0.0394 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0096 | 0.1007 | 1 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0049 | 0.0453 | 0.1018 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0055 | 0.0517 | 0.1265 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0314 | 0.0766 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0314 | 0.3138 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0055 | 0.0517 | 0.538 |
Echinococcus multilocularis | endoplasmin | 0.009 | 0.0937 | 0.0937 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 0.0599 | 0.1381 |
Leishmania major | heat shock protein, putative | 0.0064 | 0.0623 | 0.6077 |
Trypanosoma brucei | heat shock protein, putative | 0.0096 | 0.1007 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0314 | 0.0724 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0049 | 0.0453 | 0.4337 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0314 | 0.3138 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.016 | 0.1445 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0025 | 0.0168 | 0.0412 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0049 | 0.0453 | 0.1018 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0096 | 0.1007 | 1 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0014 | 0.0029 | 0.0071 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.016 | 0.037 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.1013 | 0.2475 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.016 | 0.1341 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0025 | 0.0168 | 0.0389 |
Schistosoma mansoni | heat shock protein | 0.0096 | 0.1007 | 0.2461 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0082 | 0.0842 | 0.8311 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0082 | 0.0842 | 0.8311 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0314 | 0.2913 |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 0.0599 | 0.0599 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0314 | 0.2909 |
Leishmania major | heat shock protein 83-1 | 0.0096 | 0.1007 | 1 |
Echinococcus granulosus | heat shock protein | 0.0096 | 0.1007 | 0.2461 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0599 | 0.1463 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.