Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Inositol-1 | 0.0038 | 0.0314 | 0.0744 |
Loa Loa (eye worm) | calpain 5 | 0.0028 | 0.0196 | 0.0464 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0017 | 0.0058 | 0.0043 |
Schistosoma mansoni | smad1 5 8 and | 0.0024 | 0.015 | 0.0804 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.0314 | 0.1175 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.0621 | 0.3333 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0108 | 0.1167 | 0.1354 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0063 | 0.0621 | 0.5327 |
Echinococcus granulosus | lamin | 0.0028 | 0.019 | 0.0424 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0058 | 0.0385 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.009 | 0.0775 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0135 | 0.1495 | 0.8019 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0045 | 0.0394 | 0.338 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0052 | 0.0279 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0063 | 0.0621 | 0.1473 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.1167 | 0.2762 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0108 | 0.1167 | 0.6257 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.1167 | 0.4361 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0024 | 0.015 | 0.0135 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0664 | 0.1573 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0135 | 0.1495 | 0.8019 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0208 | 0.1782 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0284 | 0.0672 |
Echinococcus multilocularis | muscleblind protein | 0.0151 | 0.169 | 0.1678 |
Schistosoma mansoni | Smad4 | 0.0024 | 0.015 | 0.0804 |
Brugia malayi | calpain 5 | 0.0028 | 0.0196 | 0.0464 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0017 | 0.0058 | 0.6363 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0045 | 0.0394 | 0.338 |
Schistosoma mansoni | inhibitor of apoptosis (iap) domain family member | 0.0055 | 0.0522 | 0.2801 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0208 | 0.1115 |
Brugia malayi | calpain family protein 1 | 0.0107 | 0.1156 | 0.2737 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0045 | 0.0394 | 0.1474 |
Brugia malayi | beta-lactamase | 0.0108 | 0.1167 | 0.2762 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.004 | 0.0344 | 0.2301 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.009 | 0.0775 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0108 | 0.1167 | 0.4361 |
Leishmania major | kinesin, putative | 0.0028 | 0.0196 | 0.1681 |
Echinococcus multilocularis | calpain A | 0.0112 | 0.1215 | 0.1202 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0024 | 0.015 | 0.0355 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.004 | 0.0344 | 0.2949 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.019 | 0.0449 |
Echinococcus granulosus | calpain 7 C02 family | 0.004 | 0.0344 | 0.0799 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0052 | 0.0123 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0135 | 0.1495 | 1 |
Loa Loa (eye worm) | nuclear factor I | 0.0014 | 0.0017 | 0.004 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0052 | 0.0279 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0038 | 0.0314 | 1 |
Onchocerca volvulus | 0.0029 | 0.0208 | 0.0074 | |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.004 | 0.0344 | 0.2301 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.0314 | 0.0744 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.019 | 0.0449 |
Trypanosoma brucei | calpain-like protein, putative | 0.004 | 0.0344 | 0.2949 |
Onchocerca volvulus | Deterin homolog | 0.0055 | 0.0522 | 0.1339 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0112 | 0.1215 | 0.6518 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0052 | 0.0037 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0107 | 0.1156 | 0.6201 |
Echinococcus granulosus | inhibitor of apoptosis protein | 0.0055 | 0.0522 | 0.1232 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0052 | 0.0123 |
Trypanosoma cruzi | kinesin, putative | 0.0028 | 0.0196 | 0.1312 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0208 | 0.1115 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0024 | 0.015 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0017 | 0.004 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0063 | 0.0621 | 0.0688 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0052 | 0.0037 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0108 | 0.1167 | 0.4361 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.1167 | 0.1354 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0108 | 0.1167 | 0.1154 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0314 | 0.1686 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0108 | 0.1167 | 0.1354 |
Giardia lamblia | Cathepsin B precursor | 0.0045 | 0.0394 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0314 | 0.2102 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.069 | 0.8251 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0045 | 0.0394 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.1167 | 0.2762 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0024 | 0.015 | 0.0135 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0112 | 0.1215 | 0.6518 |
Trypanosoma brucei | calpain-like protein, putative | 0.004 | 0.0344 | 0.2949 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0621 | 0.4934 |
Echinococcus multilocularis | calpain | 0.004 | 0.0344 | 0.033 |
Echinococcus multilocularis | musashi | 0.0028 | 0.019 | 0.0175 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0314 | 0.2694 |
Echinococcus multilocularis | inhibitor of apoptosis protein | 0.0055 | 0.0522 | 0.0508 |
Echinococcus granulosus | Smad4 | 0.0024 | 0.015 | 0.0328 |
Onchocerca volvulus | 0.0067 | 0.0664 | 0.191 | |
Trypanosoma brucei | kinesin, putative | 0.0028 | 0.0196 | 0.1681 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0017 | 0.0058 | 0.0493 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.1167 | 0.2762 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0058 | 0.0103 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0058 | 0.0043 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.009 | 0.004 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.1167 | 0.4361 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.1167 | 0.4361 |
Plasmodium vivax | calpain, putative | 0.004 | 0.0344 | 0.2583 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.019 | 0.0424 |
Loa Loa (eye worm) | calpain | 0.004 | 0.0344 | 0.0815 |
Brugia malayi | MH2 domain containing protein | 0.0024 | 0.015 | 0.0355 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0055 | 0.0522 | 0.1237 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0484 | 0.1145 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.004 | 0.0344 | 0.2301 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0112 | 0.1215 | 0.2914 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0108 | 0.1167 | 0.2762 |
Mycobacterium ulcerans | lipase LipD | 0.0108 | 0.1167 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0108 | 0.1167 | 0.2762 |
Brugia malayi | Muscleblind-like protein | 0.0151 | 0.169 | 0.4001 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0314 | 0.1175 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0108 | 0.1167 | 0.1354 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0314 | 0.2694 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0024 | 0.015 | 0.0804 |
Trypanosoma brucei | calpain-like protein, putative | 0.004 | 0.0344 | 0.2949 |
Trypanosoma cruzi | calpain cysteine peptidase, putative | 0.004 | 0.0344 | 0.2301 |
Echinococcus multilocularis | cathepsin b | 0.0135 | 0.1495 | 0.1483 |
Loa Loa (eye worm) | cathepsin B | 0.0045 | 0.0394 | 0.0934 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.004 | 0.0344 | 0.2949 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0079 | 0.0812 | 0.0798 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.004 | 0.0344 | 0.2949 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.019 | 0.0449 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.009 | 0.2876 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0183 | 0.0434 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0284 | 0.1523 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.004 | 0.0344 | 0.2301 |
Brugia malayi | beta-lactamase family protein | 0.0108 | 0.1167 | 0.2762 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0812 | 0.1923 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.009 | 0.0775 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0017 | 0.0058 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0479 | 0.1133 |
Schistosoma mansoni | hypothetical protein | 0.0055 | 0.0522 | 0.2801 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0208 | 0.0193 |
Brugia malayi | MH2 domain containing protein | 0.0359 | 0.4224 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.0352 | 0.4134 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0028 | 0.0196 | 0.624 |
Echinococcus granulosus | calpain | 0.004 | 0.0344 | 0.0799 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.0314 | 0.0727 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.009 | 0.5 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0052 | 0.009 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0108 | 0.1167 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0024 | 0.015 | 0.0804 |
Schistosoma mansoni | lamin | 0.0028 | 0.019 | 0.1017 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0024 | 0.015 | 0.0355 |
Mycobacterium ulcerans | hypothetical protein | 0.0108 | 0.1167 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0135 | 0.1495 | 0.1483 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.009 | 0.0485 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.009 | 0.0605 |
Echinococcus multilocularis | calpain 7 (C02 family) | 0.004 | 0.0344 | 0.033 |
Schistosoma mansoni | calpain (C02 family) | 0.004 | 0.0344 | 0.1845 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.1167 | 0.1354 |
Onchocerca volvulus | 0.0055 | 0.0522 | 0.1339 | |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.009 | 0.0338 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0484 | 0.1145 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0058 | 0.0493 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0484 | 0.1145 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0208 | 0.0193 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.004 | 0.0344 | 0.2301 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0208 | 0.1115 |
Echinococcus multilocularis | lamin | 0.0028 | 0.019 | 0.0175 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0052 | 0.0037 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0208 | 0.0492 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0314 | 0.1175 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0195 | 0.0437 |
Onchocerca volvulus | 0.0108 | 0.1167 | 0.3931 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0108 | 0.1167 | 0.7803 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0017 | 0.0058 | 0.0493 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0063 | 0.0621 | 0.5327 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0038 | 0.0314 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.0314 | 0.2694 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.0314 | 0.03 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0359 | 0.4224 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0108 | 0.1167 | 0.2762 |
Schistosoma mansoni | lamin | 0.0028 | 0.019 | 0.1017 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0045 | 0.0394 | 0.2637 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.1167 | 0.2762 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0314 | 0.1686 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0033 | 0.0078 |
Mycobacterium ulcerans | beta-lactamase | 0.0108 | 0.1167 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0063 | 0.0621 | 0.0607 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.009 | 0.0183 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0108 | 0.1167 | 0.6257 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0112 | 0.1215 | 0.1202 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0484 | 0.1145 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.009 | 0.0214 |
Trypanosoma brucei | antigen, putative | 0.004 | 0.0344 | 0.2949 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0015 | 0.0035 |
Schistosoma mansoni | Mername-AA248 (C02 family) | 0.004 | 0.0344 | 0.1845 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0052 | 0.009 |
Leishmania major | calpain, putative,cysteine peptidase, Clan CA, family C2, putative | 0.004 | 0.0344 | 0.2949 |
Echinococcus granulosus | cathepsin b | 0.0135 | 0.1495 | 0.3594 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0284 | 0.0672 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0009 | 0.0021 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.004 | 0.0344 | 0.2301 |
Onchocerca volvulus | 0.0051 | 0.0479 | 0.1163 | |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0058 | 0.0043 |
Trypanosoma cruzi | kinesin, putative | 0.0028 | 0.0196 | 0.1312 |
Brugia malayi | isocitrate dehydrogenase | 0.0017 | 0.0058 | 0.0136 |
Echinococcus granulosus | calpain A | 0.0112 | 0.1215 | 0.2914 |
Echinococcus multilocularis | hypothetical protein | 0.004 | 0.0344 | 0.033 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0208 | 0.1356 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0017 | 0.004 |
Toxoplasma gondii | cathepsin B | 0.0045 | 0.0394 | 0.338 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 0.2675 | 1 |
Echinococcus granulosus | calpain A | 0.004 | 0.0344 | 0.0799 |
Trichomonas vaginalis | esterase, putative | 0.0108 | 0.1167 | 0.4361 |
Brugia malayi | Isocitrate dehydrogenase | 0.0017 | 0.0058 | 0.0136 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0017 | 0.0058 | 0.0493 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.004 | 0.0344 | 0.1845 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0522 | 0.1237 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.004 | 0.0344 | 0.2301 |
Schistosoma mansoni | calpain C (C02 family) | 0.004 | 0.0344 | 0.1845 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0024 | 0.015 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.1156 | 0.2737 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0017 | 0.0058 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.1167 | 0.2762 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.019 | 0.0449 |
Schistosoma mansoni | smad1 5 8 and | 0.0024 | 0.015 | 0.0804 |
Echinococcus granulosus | calpain 5 | 0.004 | 0.0344 | 0.0799 |
Loa Loa (eye worm) | Smad1 | 0.0024 | 0.015 | 0.0355 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.169 | 0.4001 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0058 | 0.0493 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.004 | 0.0344 | 0.1845 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.009 | 0.0214 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0151 | 0.169 | 0.1678 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0108 | 0.1167 | 0.1354 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.009 | 0.0296 |
Brugia malayi | calpain 7 | 0.004 | 0.0344 | 0.0815 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.0621 | 0.3333 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0052 | 0.0123 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0621 | 0.4934 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0052 | 0.0279 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0058 | 0.0043 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0079 | 0.0812 | 0.1923 |
Brugia malayi | calpain family protein 1 | 0.0107 | 0.1156 | 0.2737 |
Echinococcus granulosus | baculoviral IAP repeat containing protein | 0.0055 | 0.0522 | 0.1232 |
Echinococcus multilocularis | tumor protein p63 | 0.0352 | 0.4134 | 0.4125 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0055 | 0.0522 | 0.1237 |
Mycobacterium leprae | conserved hypothetical protein | 0.0108 | 0.1167 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0108 | 0.1167 | 1 |
Entamoeba histolytica | calpain large subunit domain III containing protein | 0.0028 | 0.0196 | 0.624 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.0479 | 0.2568 |
Leishmania major | hypothetical protein, conserved | 0.0108 | 0.1167 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0151 | 0.169 | 0.4067 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0052 | 0.009 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.1865 | 1 |
Echinococcus multilocularis | geminin | 0.0165 | 0.1865 | 0.1852 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0017 | 0.0058 | 0.0309 |
Brugia malayi | Pre-SET motif family protein | 0.0204 | 0.2333 | 0.5522 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0359 | 0.4224 | 1 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0107 | 0.1156 | 0.2737 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0135 | 0.1495 | 0.8019 |
Schistosoma mansoni | smad | 0.0024 | 0.015 | 0.0804 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0108 | 0.1167 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0135 | 0.1495 | 0.8019 |
Echinococcus multilocularis | baculoviral IAP repeat containing protein | 0.0055 | 0.0522 | 0.0508 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0108 | 0.1167 | 0.2762 |
Echinococcus multilocularis | Smad4 | 0.0024 | 0.015 | 0.0135 |
Onchocerca volvulus | 0.0108 | 0.1167 | 0.3931 | |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0108 | 0.1167 | 0.1354 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0017 | 0.0058 | 0.0385 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0208 | 0.1115 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0108 | 0.1167 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0009 | 0.0021 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.0033 | 0.0078 |
Brugia malayi | MH2 domain containing protein | 0.0024 | 0.015 | 0.0355 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0108 | 0.1167 | 0.2797 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0108 | 0.1167 | 0.7803 |
Trypanosoma brucei | calpain-like protein, putative | 0.004 | 0.0344 | 0.2949 |
Plasmodium vivax | hypothetical protein, conserved | 0.0108 | 0.1167 | 1 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.004 | 0.0344 | 0.2301 |
Brugia malayi | Smad1 | 0.0024 | 0.015 | 0.0355 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.019 | 0.1017 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.019 | 0.0449 |
Echinococcus granulosus | geminin | 0.0165 | 0.1865 | 0.4491 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0017 | 0.004 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.019 | 0.0175 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0052 | 0.0279 |
Schistosoma mansoni | inhibitor of apoptosis protein | 0.0055 | 0.0522 | 0.2801 |
Brugia malayi | MH1 domain containing protein | 0.0024 | 0.015 | 0.0355 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.1167 | 0.1354 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0038 | 0.0314 | 0.208 |
Giardia lamblia | Cathepsin B precursor | 0.0045 | 0.0394 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.169 | 0.4001 |
Brugia malayi | MH1 domain containing protein | 0.0024 | 0.015 | 0.0355 |
Onchocerca volvulus | 0.0232 | 0.2675 | 1 | |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0204 | 0.2333 | 0.5522 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0034 | 0.0266 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0208 | 0.0492 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1008 | 0.2387 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.009 | 0.0485 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.1167 | 0.2762 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0621 | 0.4934 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.009 | 1 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0108 | 0.1167 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.1865 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0314 | 0.2102 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0052 | 0.0123 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.009 | 0.0605 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C2, putative | 0.004 | 0.0344 | 0.2949 |
Echinococcus multilocularis | smad | 0.0024 | 0.015 | 0.0135 |
Echinococcus granulosus | smad | 0.0024 | 0.015 | 0.0328 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.009 | 0.0076 |
Mycobacterium leprae | Probable lipase LipE | 0.0108 | 0.1167 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.1495 | 0.354 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.019 | 0.0424 |
Onchocerca volvulus | 0.0108 | 0.1167 | 0.3931 | |
Echinococcus granulosus | cathepsin b | 0.0135 | 0.1495 | 0.3594 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0135 | 0.1495 | 0.354 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.004 | 0.0344 | 0.2301 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0045 | 0.0394 | 0.2115 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0208 | 0.0468 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0108 | 0.1167 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0522 | 0.1237 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.009 | 0.0338 |
Echinococcus multilocularis | calpain 5 | 0.004 | 0.0344 | 0.033 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.