TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 528.569 | Formula: C27H31F3N6O2
H donors: 3 H acceptors: 3 LogP: 5.84 Rotable bonds: 13
Rule of 5 violations (Lipinski): 2
SMILES: O=C(OC(C)(C)C)C/N=C(\Nc1ccc(cc1)C(F)(F)F)/Nc1nc(C)cc(n1)NCCc1ccccc1
InChi: 1S/C27H31F3N6O2/c1-18-16-22(31-15-14-19-8-6-5-7-9-19)35-25(33-18)36-24(32-17-23(37)38-26(2,3)4)34-21-12-10-20(11-13-21)27(28,29)30/h5-13,16H,14-15,17H2,1-4H3,(H3,31,32,33,34,35,36)
InChiKey: YTTOBILRWQJZIY-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Plasmodium falciparum	importin beta, putative	0.0028	0.013	0.1599
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma brucei	importin beta-1 subunit, putative	0.0028	0.013	0.03
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Trypanosoma cruzi	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0022	0.0039	0.0037
Leishmania major	hypothetical protein, conserved	0.0025	0.0089	0.0184
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 5	0.0022	0.0039	0.0039
Brugia malayi	GTP-binding nuclear protein RAN/TC4	0.0021	0.0026	0.0021
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.025	0.3243	0.3243
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0025	0.0086	0.0163
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0047	0.0399	0.0399
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Leishmania major	lanosterol 14-alpha-demethylase, putative	0.009	0.0993	0.2789
Echinococcus granulosus	chromobox protein 1	0.0068	0.0695	0.0695
Loa Loa (eye worm)	glutaminase 2	0.0268	0.3501	0.3501
Echinococcus granulosus	dnaJ subfamily B	0.0455	0.6126	0.6126
Schistosoma mansoni	ubiquitin-specific peptidase 14 (C19 family)	0.0022	0.0039	0.0056
Schistosoma mansoni	ubiquitin-specific peptidase 9X (C19 family)	0.0022	0.0039	0.0056
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Brugia malayi	Cytochrome P450 family protein	0.009	0.0993	0.0989
Toxoplasma gondii	aldehyde dehydrogenase	0.025	0.3243	1
Plasmodium falciparum	phd finger protein, putative	0.0029	0.0137	0.1701
Echinococcus multilocularis	lipoxygenase domain containing protein	0.0019	0.0005	0.0005
Trichomonas vaginalis	ap endonuclease, putative	0.0075	0.0784	0.2029
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.0029	0.0137	0.0216
Onchocerca volvulus		0.0022	0.0039	0.0189
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0268	0.3495	0.3495
Trichomonas vaginalis	chromobox protein, putative	0.0068	0.0695	0.1793
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	chromobox protein, putative	0.0068	0.0695	0.1793
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0094	0.1051	0.1051
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.3761	1
Echinococcus multilocularis	chromobox protein 1	0.0068	0.0695	0.0695
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.025	0.3243	0.3243
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Plasmodium falciparum	thioredoxin reductase	0.0047	0.0399	0.5061
Leishmania major	ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Echinococcus multilocularis		0.009	0.0993	0.0993
Schistosoma mansoni	ubiquitin-specific peptidase 5 (C19 family)	0.0022	0.0039	0.0056
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Mycobacterium ulcerans	cytochrome P450 51B1 Cyp51B1	0.009	0.0993	0.2339
Trichomonas vaginalis	chromobox protein, putative	0.0041	0.0315	0.0774
Loa Loa (eye worm)	glutaminase	0.0268	0.3501	0.3501
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	chromobox protein, putative	0.0041	0.0315	0.0774
Mycobacterium ulcerans	cytochrome P450 142A3 Cyp142A3	0.009	0.0993	0.2339
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma cruzi	importin beta-1 subunit, putative	0.0023	0.0055	0.0085
Loa Loa (eye worm)	PHD-finger family protein	0.002	0.002	0.002
Echinococcus multilocularis	Polycystic kidney disease protein	0.0019	0.0005	0.0005
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Schistosoma mansoni	cytochrome P450	0.009	0.0993	0.1614
Brugia malayi	PHD-finger family protein	0.0029	0.0137	0.0132
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Schistosoma mansoni	ubiquitin-specific peptidase 45 (C19 family)	0.0022	0.0039	0.0056
Echinococcus granulosus	zinc finger protein	0.0023	0.0054	0.0054
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Brugia malayi	jmjC domain containing protein	0.004	0.0297	0.0292
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0039	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Leishmania major	cytochrome p450-like protein	0.009	0.0993	0.2789
Mycobacterium tuberculosis	Possible cytochrome P450 135A1 Cyp135A1	0.009	0.0993	0.2089
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus granulosus	lysine specific demethylase 5A	0.004	0.0297	0.0297
Mycobacterium tuberculosis	Probable dehydrogenase	0.0108	0.1248	0.2987
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 7	0.0022	0.0039	0.0039
Echinococcus granulosus	RUN	0.0019	0.0005	0.0005
Echinococcus multilocularis	fetal alzheimer antigen, falz	0.0026	0.0095	0.0095
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0023	0.0055	0.0079
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Trypanosoma cruzi	Lanosterol 14-alpha demethylase	0.009	0.0993	0.2789
Schistosoma mansoni	hypothetical protein	0.0299	0.3938	0.6426
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0022	0.0039	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma brucei	PAB1-binding protein , putative	0.0025	0.0089	0.0184
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Toxoplasma gondii	hypothetical protein	0.0022	0.0039	0.0043
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Brugia malayi	jmjC domain containing protein	0.0094	0.1051	0.1046
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0025	0.0086	0.0163
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus granulosus	Ubiquitin carboxyl terminal hydrolase 48	0.0022	0.0039	0.0039
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Echinococcus multilocularis	ubiquitin specific protease 41	0.0268	0.3495	0.3495
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus granulosus	5'partial\|Ubiquitin carboxyl terminal hydrolase 48	0.0022	0.0039	0.0039
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0041	0.0315	0.1697
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.0442
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.3761	1
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0039	0.0039
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Toxoplasma gondii	thioredoxin reductase	0.0047	0.0399	0.116
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Mycobacterium tuberculosis	Probable cytochrome P450 140 Cyp140	0.009	0.0993	0.2089
Toxoplasma gondii	PHD-finger domain-containing protein	0.0029	0.0137	0.0348
Brugia malayi	Bromodomain containing protein	0.0031	0.017	0.0165
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 36	0.0022	0.0039	0.0039
Mycobacterium tuberculosis	Probable cytochrome P450 monooxygenase 142 Cyp142	0.009	0.0993	0.2089
Schistosoma mansoni	ubiquitin-specific peptidase 22 (C19 family)	0.0022	0.0039	0.0056
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0062	0.0607	0.0607
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Schistosoma mansoni	jumonji domain containing protein	0.0074	0.0781	0.1267
Echinococcus granulosus	ubiquitin specific peptidase 30 (C19 family)	0.0022	0.0039	0.0039
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0025	0.0086	0.0163
Echinococcus multilocularis	jumonji domain containing protein	0.004	0.0295	0.0295
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Plasmodium vivax	thioredoxin reductase, putative	0.0047	0.0399	0.5061
Mycobacterium ulcerans	aldehyde dehydrogenase	0.025	0.3243	0.9213
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0022	0.0039	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.025	0.3243	1
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Mycobacterium tuberculosis	Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM)	0.009	0.0993	0.2089
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 7	0.0022	0.0039	0.0039
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0108	0.1248	0.2987
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0039	0.0039
Trypanosoma cruzi	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 14	0.0022	0.0039	0.0037
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Echinococcus multilocularis	transfer RNA-Lys	0.0035	0.0227	0.0227
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Leishmania major	importin beta-1 subunit, putative	0.0023	0.0055	0.0085
Loa Loa (eye worm)	hypothetical protein	0.0431	0.5785	0.5785
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0118	0.1386	0.4227
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma cruzi	cytochrome p450-like protein, putative	0.009	0.0993	0.2789
Mycobacterium tuberculosis	Cytochrome P450 121 Cyp121	0.009	0.0993	0.2089
Mycobacterium tuberculosis	Probable cytochrome P450 144 Cyp144	0.009	0.0993	0.2089
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0075	0.0784	0.2185
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0025	0.0086	0.0163
Trichomonas vaginalis	conserved hypothetical protein	0.0038	0.0274	0.0664
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0372	0.0372
Schistosoma mansoni	hypothetical protein	0.0165	0.2049	0.334
Mycobacterium tuberculosis	Probable reductase	0.0108	0.1248	0.2987
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus granulosus	thioredoxin glutathione reductase	0.0047	0.0399	0.0399
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0268	0.3495	0.9287
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 4	0.0268	0.3495	0.9287
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0043
Echinococcus granulosus	PHD finger protein rhinoceros	0.0029	0.0137	0.0137
Plasmodium vivax	hypothetical protein, conserved	0.0029	0.0137	0.1701
Schistosoma mansoni	lipoxygenase	0.008	0.0861	0.1399
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0075	0.0784	0.0784
Loa Loa (eye worm)	hypothetical protein	0.0069	0.071	0.071
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0075	0.0784	0.2185
Mycobacterium ulcerans	cytochrome P450 185A4 Cyp185A4	0.017	0.2125	0.5797
Mycobacterium tuberculosis	Probable cytochrome P450 143 Cyp143	0.009	0.0993	0.2089
Schistosoma mansoni	ran	0.0021	0.0026	0.0034
Toxoplasma gondii	ubiquitin-specific protease USP4	0.0022	0.0039	0.0043
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0022	0.0039	0.0037
Schistosoma mansoni	hypothetical protein	0.0149	0.1829	0.2981
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0028	0.013	0.013
Echinococcus granulosus	ubiquitin specific protease 41	0.0268	0.3495	0.3495
Mycobacterium ulcerans	cytochrome P450 150A6 Cyp150A6	0.009	0.0993	0.2339
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0268	0.3495	1
Schistosoma mansoni	jumonji/arid domain-containing protein	0.004	0.0297	0.0477
Mycobacterium ulcerans	cytochrome P450 140A5 Cyp140A5	0.009	0.0993	0.2339
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0268	0.3495	1
Toxoplasma gondii	LsmAD domain-containing protein	0.0025	0.0089	0.0198
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Mycobacterium ulcerans	cytochrome P450 187A5 Cyp187A5	0.009	0.0993	0.2339
Mycobacterium tuberculosis	Possible cytochrome P450 126 Cyp126	0.009	0.0993	0.2089
Brugia malayi	Importin beta-1 subunit	0.0028	0.013	0.0125
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0043
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma brucei	importin beta-1 subunit, putative	0.0028	0.013	0.03
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.012	0.1417	0.598
Mycobacterium ulcerans	cytochrome P450 143A3 Cyp143A3	0.009	0.0993	0.2339
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Schistosoma mansoni	hypothetical protein	0.0029	0.0137	0.0216
Loa Loa (eye worm)	cytochrome P450	0.009	0.0993	0.0993
Echinococcus granulosus	chromobox protein 1	0.0068	0.0695	0.0695
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0268	0.3495	0.9287
Onchocerca volvulus		0.0022	0.0039	0.0189
Brugia malayi	Thioredoxin reductase	0.0047	0.0399	0.0394
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0039	0.0039
Trypanosoma brucei	Lanosterol 14-alpha demethylase	0.009	0.0993	0.2789
Brugia malayi	PAS domain containing protein	0.0047	0.04	0.0395
Echinococcus multilocularis	cpg binding protein	0.0066	0.0664	0.0664
Entamoeba histolytica	hypothetical protein	0.0022	0.0039	0.0037
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0023	0.0055	0.0079
Entamoeba histolytica	hypothetical protein	0.0023	0.0055	0.0079
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0039
Schistosoma mansoni	ubiquitin-specific peptidase 42 (C19 family)	0.0022	0.0039	0.0056
Toxoplasma gondii	UBA/TS-N domain-containing protein	0.0022	0.0039	0.0043
Mycobacterium ulcerans	cytochrome P450 143A4 Cyp143A4	0.009	0.0993	0.2339
Mycobacterium tuberculosis	Probable cytochrome P450 137 Cyp137	0.009	0.0993	0.2089
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0043
Giardia lamblia	Fructose-bisphosphate aldolase	0.0287	0.3761	1
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 23	0.0022	0.0039	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Echinococcus granulosus	single minded 2	0.0035	0.0227	0.0227
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0039	0.0039
Echinococcus multilocularis	ubiquitin specific peptidase 42 (C19 family)	0.0022	0.0039	0.0039
Brugia malayi	ubiquitin specific protease 14	0.0022	0.0039	0.0034
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.0037
Echinococcus multilocularis	chromobox protein 1	0.0068	0.0695	0.0695
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.3761	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Echinococcus multilocularis	lipoxygenase domain containing protein	0.0019	0.0005	0.0005
Schistosoma mansoni	ubiquitin-specific peptidase 44 (C19 family)	0.0022	0.0039	0.0056
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Mycobacterium tuberculosis	Probable cytochrome P450 138 Cyp138	0.009	0.0993	0.2089
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Toxoplasma gondii	HEAT repeat-containing protein	0.0028	0.013	0.0323
Loa Loa (eye worm)	thioredoxin reductase	0.0047	0.0399	0.0399
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.0089	0.0184
Schistosoma mansoni	ap endonuclease	0.0075	0.0784	0.1272
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Onchocerca volvulus		0.0035	0.0227	0.1219
Loa Loa (eye worm)	cytochrome P450 family protein	0.017	0.2125	0.2125
Trichomonas vaginalis	chromodomain-helicase-DNA-binding protein, putative	0.0025	0.0086	0.0163
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Loa Loa (eye worm)	GTP-binding nuclear protein RAN/TC4	0.0021	0.0026	0.0026
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Schistosoma mansoni	ubiquitin-specific peptidase 10 (C19 family)	0.0022	0.0039	0.0056
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0043
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0075	0.0784	0.0784
Plasmodium vivax	hypothetical protein, conserved	0.0022	0.0039	0.0442
Echinococcus multilocularis	zinc finger protein	0.0023	0.0054	0.0054
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0039	0.0039
Schistosoma mansoni	ubiquitin-specific peptidase 46 (C19 family)	0.0022	0.0039	0.0056
Schistosoma mansoni	hypothetical protein	0.002	0.002	0.0025
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0264	0.0264
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0431	0.5785	0.5785
Mycobacterium ulcerans	aldehyde dehydrogenase	0.025	0.3243	0.9213
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0022	0.0039	0.0037
Giardia lamblia	PHD finger protein 15	0.0029	0.0137	0.0299
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Brugia malayi	Bromodomain containing protein	0.0077	0.0818	0.0813
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Loa Loa (eye worm)	doublecortin family protein	0.0019	0.0005	0.0005
Schistosoma mansoni	aldehyde dehydrogenase	0.025	0.3243	0.5291
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0075	0.0784	0.2185
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0043
Mycobacterium tuberculosis	Probable cytochrome P450 125 Cyp125	0.009	0.0993	0.2089
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 24	0.0022	0.0039	0.0039
Echinococcus granulosus	jumonji domain containing protein	0.004	0.0295	0.0295
Trypanosoma brucei	cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0075	0.0784	0.2029
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0039	0.0039
Schistosoma mansoni	ubiquitin-specific peptidase 24 (C19 family)	0.0022	0.0039	0.0056
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.3761	1
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 20	0.0022	0.0039	0.0039
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Schistosoma mansoni	ubiquitin-specific peptidase 7 (C19 family)	0.0022	0.0039	0.0056
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Schistosoma mansoni	family C19 non-peptidase homologue (C19 family)	0.0022	0.0039	0.0056
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.025	0.3243	0.9275
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus granulosus	Peptidase C19 ubiquitin carboxyl terminal hydrolase 2	0.0268	0.3495	0.3495
Brugia malayi	bHLH-PAS transcription factor	0.0035	0.0227	0.0222
Mycobacterium tuberculosis	Probable cytochrome P450 139 Cyp139	0.009	0.0993	0.2089
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0268	0.3495	0.9287
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0035	0.0231	0.0231
Echinococcus multilocularis	u4:u6.u5 tri snrnp associated protein 2	0.0022	0.0039	0.0039
Schistosoma mansoni	hypothetical protein	0.0022	0.0039	0.0056
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase family 2, putative	0.0022	0.0039	0.0442
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0108	0.1248	0.2987
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Mycobacterium ulcerans	cytochrome P450 191A3 Cyp191A3	0.009	0.0993	0.2339
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 13, putative	0.0022	0.0039	0.0442
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0075	0.0784	0.5
Toxoplasma gondii	exonuclease III APE	0.0075	0.0784	0.2355
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Toxoplasma gondii	ubiquitin specific protease 39 isoform 2, putative	0.0022	0.0039	0.0043
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0022	0.0039	0.0039
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Brugia malayi	RNA, U transporter 1	0.008	0.0855	0.0851
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase 5, putative	0.0022	0.0039	0.0037
Echinococcus multilocularis	peregrin	0.0031	0.017	0.017
Schistosoma mansoni	importin beta-1	0.0028	0.013	0.0203
Echinococcus multilocularis	RUN	0.0019	0.0005	0.0005
Trichomonas vaginalis	glutaminase, putative	0.0268	0.3501	0.9303
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase 5, putative	0.0022	0.0039	0.0037
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Schistosoma mansoni	ubiquitin-specific peptidase 2 (C19 family)	0.0268	0.3495	0.5702
Loa Loa (eye worm)	ubiquitin specific peptidase 39	0.0022	0.0039	0.0039
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Plasmodium falciparum	U4/U6.U5 tri-snRNP-associated protein 2, putative	0.0022	0.0039	0.0442
Giardia lamblia	Hypothetical protein	0.0022	0.0039	0.0037
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0484	0.6536	0.6536
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0039	0.0039
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 13, putative	0.0022	0.0039	0.0442
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0005	0.0005
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 14	0.0022	0.0039	0.0039
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0075	0.0784	1
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0287	0.3761	1
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0039	0.0039
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 8	0.0268	0.3495	0.3495
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Brugia malayi	Bromodomain containing protein	0.0038	0.0263	0.0258
Trypanosoma cruzi	Lanosterol 14-alpha demethylase	0.009	0.0993	0.2789
Loa Loa (eye worm)	CYP4Cod1	0.017	0.2125	0.2125
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Plasmodium vivax	U4/U6.U5 tri-snRNP-associated protein 2, putative	0.0022	0.0039	0.0442
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0094	0.1051	0.1051
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus multilocularis	snurportin 1	0.0299	0.3938	0.3938
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.3761	1
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0062	0.0607	0.0607
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Mycobacterium tuberculosis	Probable cytochrome P450 141 Cyp141	0.009	0.0993	0.2089
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Loa Loa (eye worm)	PHD-finger family protein	0.0029	0.0137	0.0137
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0035	0.0231	0.0231
Plasmodium vivax	GTP-binding nuclear protein RAN/TC4, putative	0.0021	0.0026	0.0264
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0022	0.0039	0.0037
Schistosoma mansoni	jumonji/arid domain-containing protein	0.004	0.0297	0.0477
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 24	0.0022	0.0039	0.0039
Echinococcus multilocularis	lysine specific demethylase 5A	0.0035	0.0222	0.0222
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0039
Mycobacterium tuberculosis	Probable fructose-bisphosphate aldolase Fba	0.014	0.1702	0.4582
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 12	0.0022	0.0039	0.0039
Plasmodium falciparum	GTP-binding nuclear protein RAN/TC4	0.0021	0.0026	0.0264
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Trypanosoma cruzi	PAB1-binding protein , putative	0.0025	0.0089	0.0184
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0039	0.0039
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Echinococcus granulosus	lipoxygenase domain containing protein	0.0019	0.0005	0.0005
Mycobacterium ulcerans	cytochrome P450 144A4 Cyp144A4	0.009	0.0993	0.2339
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 2, putative	0.0022	0.0039	0.0442
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Mycobacterium ulcerans	glutaminase	0.0268	0.3501	1
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0025	0.0086	0.0163
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Schistosoma mansoni	single-minded	0.0047	0.04	0.0645
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 8	0.0268	0.3495	0.3495
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0075	0.0784	0.0784
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.0442
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Schistosoma mansoni	zinc finger protein	0.0023	0.0054	0.008
Loa Loa (eye worm)	heterochromatin protein 1	0.0068	0.0695	0.0695
Leishmania major	cytochrome p450-like protein	0.009	0.0993	0.2789
Mycobacterium ulcerans	cytochrome P450 123A3 Cyp123A3	0.009	0.0993	0.2339
Trypanosoma brucei	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Onchocerca volvulus		0.0061	0.059	0.3204
Loa Loa (eye worm)	cytochrome P450 family protein	0.0226	0.2903	0.2903
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Echinococcus multilocularis	ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase	0.0022	0.0039	0.0039
Brugia malayi	chromobox protein homolog 3	0.0038	0.0274	0.0269
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0043
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0129	0.1547	0.2518
Trypanosoma cruzi	cytochrome P450, putative	0.017	0.2125	0.6051
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	chromodomain-helicase-DNA-binding protein, putative	0.0025	0.0086	0.0163
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Brugia malayi	ubiquitin carboxyl-terminal hydrolase 46	0.0022	0.0039	0.0034
Echinococcus multilocularis	GTP binding nuclear protein Ran	0.0021	0.0026	0.0026
Schistosoma mansoni	bromodomain containing protein	0.0066	0.0656	0.1064
Mycobacterium ulcerans	cytochrome P450 125A7 Cyp125A7	0.009	0.0993	0.2339
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 20	0.0022	0.0039	0.0039
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.3761	1
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0025	0.0086	0.0163
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0022	0.0039	0.0037
Brugia malayi	Cytochrome P450 family protein	0.017	0.2125	0.2121
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0039
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.0089	0.1083
Trypanosoma brucei	trypanothione reductase	0.0047	0.0399	0.1076
Echinococcus multilocularis	expressed protein	0.0022	0.0039	0.0039
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 7	0.0022	0.0039	0.0039
Plasmodium falciparum	ubiquitin specific protease, putative	0.0022	0.0039	0.0442
Echinococcus granulosus	Polycystic kidney disease protein	0.0019	0.0005	0.0005
Schistosoma mansoni	ubiquitin-specific peptidase 16 (C19 family)	0.0022	0.0039	0.0056
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Loa Loa (eye worm)	cytochrome P450 family protein	0.017	0.2125	0.2125
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0039
Schistosoma mansoni	glutaminase	0.0268	0.3501	0.5712
Onchocerca volvulus		0.0149	0.1829	1
Schistosoma mansoni	ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold	0.0022	0.0039	0.0056
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.3761	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.0442
Onchocerca volvulus		0.0022	0.0039	0.0189
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0043
Plasmodium falciparum	ubiquitin specific protease, putative	0.0022	0.0039	0.0442
Giardia lamblia	DUB-1	0.0022	0.0039	0.0037
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Schistosoma mansoni	ubiquitin-specific peptidase 30 (C19 family)	0.0022	0.0039	0.0056
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.012	0.1417	0.358
Brugia malayi	CXXC zinc finger family protein	0.0061	0.059	0.0585
Echinococcus granulosus	tm gpcr rhodopsin	0.0519	0.7026	0.7026
Mycobacterium ulcerans	cytochrome P450 105Q4 Cyp105Q4	0.009	0.0993	0.2339
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0022	0.0039	0.0039
Trypanosoma brucei	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Loa Loa (eye worm)	hypothetical protein	0.0159	0.1964	0.1964
Trichomonas vaginalis	conserved hypothetical protein	0.0027	0.0117	0.0244
Schistosoma mansoni	aldehyde dehydrogenase	0.025	0.3243	0.5291
Schistosoma mansoni	family C19 unassigned peptidase (C19 family)	0.0022	0.0039	0.0056
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.0075	0.0784	0.1352
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Schistosoma mansoni	aryl hydrocarbon receptor	0.0047	0.04	0.0645
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Mycobacterium ulcerans	cytochrome P450 189A7 Cyp189A7	0.009	0.0993	0.2339
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0108	0.1248	0.2987
Loa Loa (eye worm)	glutathione reductase	0.0047	0.0399	0.0399
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Echinococcus multilocularis	importin subunit beta 1	0.0028	0.013	0.013
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Mycobacterium leprae	Probable fructose bisphosphate aldolase Fba	0.014	0.1702	1
Brugia malayi	cytochrome P450	0.009	0.0993	0.0989
Echinococcus granulosus	GTP binding nuclear protein Ran	0.0021	0.0026	0.0026
Schistosoma mansoni	cpg binding protein	0.0066	0.0664	0.1077
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.0442
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 36	0.0022	0.0039	0.0039
Brugia malayi	PHD-finger family protein	0.0028	0.0128	0.0123
Schistosoma mansoni	chromobox protein	0.0068	0.0695	0.1128
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase	0.0022	0.0039	0.0039
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0089	0.0089
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0039
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma cruzi	cytochrome P450, putative	0.017	0.2125	0.6051
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0299	0.3938	0.3938
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Echinococcus multilocularis	Ubiquitin carboxyl terminal hydrolase 48	0.0022	0.0039	0.0039
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 14	0.0022	0.0039	0.0442
Schistosoma mansoni	ap endonuclease	0.0075	0.0784	0.1272
Schistosoma mansoni	acetyl-CoA C-acetyltransferase	0.0026	0.0095	0.0147
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0039	0.0039
Schistosoma mansoni	ubiquitin-specific peptidase 9X (C19 family)	0.0022	0.0039	0.0056
Trichomonas vaginalis	ap endonuclease, putative	0.0075	0.0784	0.2029
Schistosoma mansoni	calpain-7 (C02 family)	0.0022	0.0039	0.0056
Brugia malayi	follicle stimulating hormone receptor	0.0484	0.6536	0.6534
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.0075	0.0784	0.1699
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Schistosoma mansoni	ubiquitin-specific peptidase 4 (C19 family)	0.0022	0.0039	0.0056
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus granulosus	arachidonate 5 lipoxygenase	0.0115	0.1346	0.1346
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Plasmodium falciparum	glutathione reductase	0.0047	0.0399	0.5061
Mycobacterium ulcerans	cytochrome P450 187A4 Cyp187A4	0.009	0.0993	0.2339
Schistosoma mansoni	ran	0.0021	0.0026	0.0034
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0149	0.1829	0.1825
Onchocerca volvulus	Alhambra homolog	0.0029	0.0137	0.0726
Schistosoma mansoni	survival motor neuron protein	0.0149	0.1829	0.2981
Brugia malayi	Cytochrome P450 family protein	0.0226	0.2903	0.2899
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0005	0.0005
Mycobacterium leprae	PROBABLE NADH DEHYDROGENASE NDH	0.0108	0.1248	0.36
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 16	0.0022	0.0039	0.0039
Mycobacterium tuberculosis	Probable cytochrome P450 128 Cyp128	0.009	0.0993	0.2089
Brugia malayi	hypothetical protein	0.0022	0.0039	0.0034
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus multilocularis	geminin	0.0165	0.2049	0.2049
Mycobacterium tuberculosis	Probable cytochrome P450 136 Cyp136	0.009	0.0993	0.2089
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus granulosus	snurportin 1	0.0299	0.3938	0.3938
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.0287	0.3761	1
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0043
Mycobacterium tuberculosis	Probable cytochrome P450 124 Cyp124	0.009	0.0993	0.2089
Schistosoma mansoni	peptidase	0.0022	0.0039	0.0056
Brugia malayi	Heterochromatin protein 1	0.0068	0.0695	0.0691
Echinococcus multilocularis	dnaJ subfamily B	0.0455	0.6126	0.6126
Schistosoma mansoni	hypothetical protein	0.0165	0.2049	0.334
Mycobacterium ulcerans	aldehyde dehydrogenase	0.025	0.3243	0.9213
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.0287	0.3761	1
Schistosoma mansoni	chromobox protein	0.0068	0.0695	0.1128
Echinococcus granulosus	cytochrome P450 2K1	0.009	0.0993	0.0993
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0038	0.0274	0.1473
Echinococcus granulosus	lipoxygenase domain containing protein	0.0019	0.0005	0.0005
Plasmodium vivax	ataxin-2 like protein, putative	0.0025	0.0089	0.1083
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0075	0.0784	1
Trichomonas vaginalis	importin beta-1, putative	0.0023	0.0055	0.0079
Echinococcus granulosus	fetal alzheimer antigen falz	0.0026	0.0095	0.0095
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0274	0.0274
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0519	0.7026	0.7026
Echinococcus granulosus	cpg binding protein	0.0066	0.0664	0.0664
Mycobacterium ulcerans	cytochrome P450 124A1, Cyp124A1	0.009	0.0993	0.2339
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	conserved hypothetical protein	0.0038	0.0274	0.0664
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 22	0.0022	0.0039	0.0039
Plasmodium falciparum	ataxin-2 like protein, putative	0.0025	0.0089	0.1083
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0022	0.0039	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Mycobacterium ulcerans	cytochrome P450 188A3 Cyp188A3	0.009	0.0993	0.2339
Toxoplasma gondii	cytochrome p450 superfamily protein	0.009	0.0993	0.3007
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 12	0.0022	0.0039	0.0039
Brugia malayi	glutaminase DH11.1	0.0268	0.3501	0.3498
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.004	0.0297	0.0297
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 16	0.0022	0.0039	0.0039
Mycobacterium ulcerans	cytochrome P450 108B4 Cyp108B4	0.009	0.0993	0.2339
Trichomonas vaginalis	conserved hypothetical protein	0.0022	0.0039	0.0037
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0022	0.0039	0.0037
Brugia malayi	Cytochrome P450 family protein	0.017	0.2125	0.2121
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Mycobacterium tuberculosis	Possible cytochrome P450 135B1 Cyp135B1	0.009	0.0993	0.2089
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0075	0.0784	0.2185
Echinococcus granulosus	peregrin	0.0031	0.017	0.017
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0268	0.3495	0.3492
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 5	0.0022	0.0039	0.0039
Schistosoma mansoni	calpain-7 (C02 family)	0.0022	0.0039	0.0056
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0043
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0029	0.0137	0.0137
Trypanosoma cruzi	trypanothione reductase, putative	0.0047	0.0399	0.1076
Brugia malayi	exodeoxyribonuclease III family protein	0.0075	0.0784	0.0779
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0268	0.3495	1
Mycobacterium ulcerans	cytochrome P450 126A3 Cyp126A3	0.009	0.0993	0.2339
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 47	0.0022	0.0039	0.0039
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Mycobacterium tuberculosis	Probable cytochrome P450 123 Cyp123	0.009	0.0993	0.2089
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypoxia-induced factor 1	0.0146	0.1791	0.1791
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.0075	0.0784	0.2029
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 2, putative	0.0022	0.0039	0.0442
Echinococcus granulosus	geminin	0.0165	0.2049	0.2049
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0022	0.0039	0.0037
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 14	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0424	0.0424
Trichomonas vaginalis	conserved hypothetical protein	0.0268	0.3495	0.9287
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus granulosus	ubiquitin specific peptidase c family	0.0022	0.0039	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase	0.0022	0.0039	0.0039
Mycobacterium ulcerans	cytochrome p450 150 cyp150	0.009	0.0993	0.2339
Schistosoma mansoni	ubiquitin-specific peptidase 8 (C19 family)	0.0268	0.3495	0.5702
Loa Loa (eye worm)	hypothetical protein	0.003	0.0158	0.0158
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0022	0.0039	0.0034
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0061	0.059	0.059
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Leishmania major	trypanothione reductase	0.0047	0.0399	0.1076
Treponema pallidum	fructose-bisphosphate aldolase	0.0287	0.3761	1
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase family 2 protein	0.0022	0.0039	0.0043
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0108	0.1248	0.2987
Mycobacterium tuberculosis	Probable cytochrome P450 132 Cyp132	0.009	0.0993	0.2089
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 4	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0039	0.0039
Schistosoma mansoni	ubiquitin-specific peptidase 48 (C19 family)	0.0022	0.0039	0.0056
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus granulosus	importin subunit beta 1	0.0028	0.013	0.013
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0022	0.0039	0.0039
Mycobacterium tuberculosis	Probable oxidoreductase	0.012	0.1417	0.358
Loa Loa (eye worm)	jmjC domain-containing protein	0.0059	0.0565	0.0565
Schistosoma mansoni	hypothetical protein	0.0455	0.6126	1
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 7	0.0022	0.0039	0.0039
Toxoplasma gondii	PHD-finger domain-containing protein	0.0029	0.0137	0.0348
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Mycobacterium tuberculosis	Probable cytochrome P450 130 Cyp130	0.009	0.0993	0.2089
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0268	0.3495	1
Trichomonas vaginalis	conserved hypothetical protein	0.0027	0.0117	0.0244
Loa Loa (eye worm)	hypothetical protein	0.0081	0.0868	0.0868
Echinococcus granulosus	u4:u6.u5 tri snrnp associated protein 2	0.0022	0.0039	0.0039
Schistosoma mansoni	cpg binding protein	0.0061	0.059	0.0955
Brugia malayi	hypothetical protein	0.0025	0.0089	0.0084
Schistosoma mansoni	lipoxygenase	0.0115	0.1346	0.2191
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0043
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Brugia malayi	glutathione reductase	0.0047	0.0399	0.0394
Plasmodium vivax	ubiquitin specific protease, putative	0.0022	0.0039	0.0442
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Schistosoma mansoni	cpg binding protein	0.0066	0.0664	0.1077
Schistosoma mansoni	hypothetical protein	0.009	0.0993	0.1614
Mycobacterium ulcerans	fructose-bisphosphate aldolase	0.014	0.1702	0.4506
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0022	0.0039	0.0037
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 47	0.0022	0.0039	0.0039
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0022	0.0039	0.004
Brugia malayi	hypothetical protein	0.0159	0.1964	0.196
Trypanosoma brucei	cytochrome P450, putative	0.017	0.2125	0.6051
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 1, putative	0.0022	0.0039	0.0442
Plasmodium vivax	importin-beta 2, putative	0.0028	0.013	0.1599
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase 46	0.0022	0.0039	0.0039
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Mycobacterium ulcerans	cytochrome P450 136A2 Cyp136A2	0.009	0.0993	0.2339
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0022	0.0039	0.004
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Brugia malayi	F/Y-rich N-terminus family protein	0.003	0.0154	0.0149
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0137	0.0137
Echinococcus multilocularis	arachidonate 5 lipoxygenase	0.0115	0.1346	0.1346
Leishmania major	cytochrome p450-like protein	0.017	0.2125	0.6051
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0022	0.0039	0.0039
Echinococcus multilocularis	Peptidase C19, ubiquitin carboxyl terminal hydrolase 2	0.0268	0.3495	0.3495
Brugia malayi	hypoxia-induced factor 1	0.0146	0.1791	0.1787
Onchocerca volvulus		0.003	0.0158	0.0836
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 22	0.0022	0.0039	0.0039
Plasmodium vivax	glutathione reductase, putative	0.0047	0.0399	0.5061
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.012	0.1417	0.358
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0024	0.0079	0.0121
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Loa Loa (eye worm)	jmjC domain-containing protein	0.004	0.0297	0.0297
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0022	0.0039	0.0037
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 14	0.0022	0.0039	0.0039

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL581953

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1078914