Detailed information for compound 1178094

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 642.733 | Formula: C35H46O11
  • H donors: 2 H acceptors: 5 LogP: 2.63 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 2
  • SMILES: OCC/C(=C/C(=O)OC[C@]12CCC(=C[C@H]1O[C@H]1[C@]3([C@]2(C)[C@H](OC(=O)/C=C/C=C\C(C(O)C)OCCC2=CCOC2=O)C1)CO3)C)/C
  • InChi: 1S/C35H46O11/c1-22-9-13-34(20-43-31(39)18-23(2)10-14-36)28(17-22)45-29-19-27(33(34,4)35(29)21-44-35)46-30(38)8-6-5-7-26(24(3)37)41-15-11-25-12-16-42-32(25)40/h5-8,12,17-18,24,26-29,36-37H,9-11,13-16,19-21H2,1-4H3/b7-5-,8-6+,23-18+/t24?,26?,27-,28-,29-,33-,34-,35+/m1/s1
  • InChiKey: OYYWQQXSIYGSJF-HOYSYQDDSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis musashi 0.0032 0.0037 0.0037
Schistosoma mansoni cpg binding protein 0.0094 0.0174 0.0166
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0122 0.0237 0.0237
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0024 0.0019 0.0019
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0019 0.0008 0.0008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0247 0.0515 0.0515
Trichomonas vaginalis glucosylceramidase, putative 0.0209 0.0431 0.6682
Brugia malayi nuclear hormone receptor 0.0024 0.0019 0.0131
Onchocerca volvulus 0.0037 0.0048 0.0515
Trichomonas vaginalis set domain proteins, putative 0.0279 0.0588 0.9182
Echinococcus granulosus smad 0.0019 0.0008 0.0008
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0051 0.0051
Schistosoma mansoni hypothetical protein 0.0122 0.0237 0.0229
Schistosoma mansoni cpg binding protein 0.0099 0.0186 0.0178
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0302 0.0639 0.5603
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0164
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0032 0.0249
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0051 0.0611
Echinococcus multilocularis Smad4 0.0019 0.0008 0.0008
Brugia malayi Smad1 0.0019 0.0008 0.0041
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.0407 0.6302
Echinococcus multilocularis GPCR, family 2 0.0122 0.0237 0.0237
Echinococcus granulosus mixed lineage leukemia protein mll 0.0025 0.002 0.002
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0024 0.0019 0.0019
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0051 0.0611
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0019 0.0131
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0109 0.0109
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0048 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0048 0.004
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0122 0.0237 0.0237
Brugia malayi CXXC zinc finger family protein 0.0094 0.0174 0.1501
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0024 0.0019 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0024 0.0019 0.0131
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0048 0.0048
Schistosoma mansoni retinoic acid receptor RXR 0.0024 0.0019 0.001
Schistosoma mansoni hypothetical protein 0.0107 0.0205 0.0196
Schistosoma mansoni hypothetical protein 0.0895 0.196 0.1953
Onchocerca volvulus 0.0032 0.0037 0.0321
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0051 0.0611
Echinococcus multilocularis lamin 0.0032 0.0037 0.0037
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0302 0.0639 0.5618
Echinococcus multilocularis FTZ F1 alpha 0.0024 0.0019 0.0019
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0247 0.0515 0.4527
Echinococcus granulosus dnaJ subfamily B 0.0895 0.196 0.196
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0164
Echinococcus granulosus neuropeptide s receptor 0.2003 0.4426 0.4426
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0247 0.0515 0.0507
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0024 0.0019 0.001
Loa Loa (eye worm) twinkle helicase 0.0118 0.0229 0.2009
Schistosoma mansoni cpg binding protein 0.0099 0.0186 0.0178
Schistosoma mansoni hypothetical protein 0.0122 0.0237 0.0229
Echinococcus granulosus GPCR family 2 0.0122 0.0237 0.0237
Toxoplasma gondii histone lysine methyltransferase SET1 0.0179 0.0363 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0024 0.0019 0.0164
Schistosoma mansoni hypothetical protein 0.0263 0.0552 0.0544
Echinococcus multilocularis cpg binding protein 0.0099 0.0186 0.0186
Brugia malayi MH1 domain containing protein 0.0019 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0263 0.0552 0.4854
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0024 0.0019 0.0131
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.0407 0.6302
Loa Loa (eye worm) MH2 domain-containing protein 0.0283 0.0595 0.5234
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.0407 0.6302
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0164
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0019 0.0019
Schistosoma mansoni alpha-glucosidase 0.0149 0.0297 0.0289
Echinococcus multilocularis dnaJ subfamily B 0.0895 0.196 0.196
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0413 0.0886 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0122 0.0237 0.2084
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0051 1
Echinococcus multilocularis smad 0.0019 0.0008 0.0008
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0109 0.1941
Brugia malayi ecdysteroid receptor 0.0024 0.0019 0.0131
Echinococcus multilocularis geminin 0.0545 0.118 0.118
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0048 0.004
Echinococcus granulosus intermediate filament protein 0.0032 0.0037 0.0037
Echinococcus granulosus lamin dm0 0.0032 0.0037 0.0037
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0004 0.0033
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0024 0.0019 0.0164
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0247 0.0515 0.0507
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0019 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0024 0.0019 0.0131
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0247 0.0515 0.0507
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0051 0.0449
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0024 0.0019 0.001
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0033 0.0033
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0385 0.0824 0.7241
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0019 0.001
Schistosoma mansoni Replicative DNA helicase 0.0413 0.0886 0.0878
Brugia malayi steroid hormone receptor 0.0024 0.0019 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0024 0.0019 0.0131
Loa Loa (eye worm) histone methyltransferase 0.003 0.0033 0.0289
Loa Loa (eye worm) hypothetical protein 0.0526 0.1138 1
Schistosoma mansoni survival motor neuron protein 0.0107 0.0205 0.0196
Loa Loa (eye worm) hypothetical protein 0.0122 0.0237 0.2084
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0247 0.0515 0.0515
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.0407 0.6302
Brugia malayi Intermediate filament tail domain containing protein 0.0032 0.0037 0.0292
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0024 0.0019 0.001
Loa Loa (eye worm) Smad1 0.0019 0.0008 0.0074
Plasmodium vivax SET domain protein, putative 0.0037 0.0048 0.5
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0024 0.0019 0.0019
Mycobacterium leprae Conserved hypothetical protein 0.0542 0.1172 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0019 0.0131
Loa Loa (eye worm) CXXC zinc finger family protein 0.0094 0.0174 0.1529
Loa Loa (eye worm) hypothetical protein 0.0037 0.0048 0.0421
Echinococcus multilocularis neuropeptide s receptor 0.2003 0.4426 0.4426
Loa Loa (eye worm) steroid hormone receptor 0.0024 0.0019 0.0164
Schistosoma mansoni mixed-lineage leukemia protein mll 0.02 0.0411 0.0402
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0019 0.001
Onchocerca volvulus 0.0107 0.0205 0.3267
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0247 0.0515 0.4509
Echinococcus multilocularis thyroid hormone receptor alpha 0.0024 0.0019 0.0019
Loa Loa (eye worm) intermediate filament protein 0.0032 0.0037 0.0325
Loa Loa (eye worm) hypothetical protein 0.0031 0.0036 0.0313
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0246 0.0513 0.4508
Chlamydia trachomatis replicative DNA helicase 0.0413 0.0886 0.5
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.1427 0.3145 0.7673
Echinococcus granulosus mothers against decapentaplegic 5 0.0019 0.0008 0.0008
Echinococcus multilocularis neuropeptide receptor A26 0.2003 0.4426 0.4426
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0051 0.0611
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0024 0.0019 0.001
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0051 0.0051
Brugia malayi MH1 domain containing protein 0.0019 0.0008 0.0041
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0164
Echinococcus multilocularis survival motor neuron protein 1 0.0526 0.1138 0.1138
Loa Loa (eye worm) transcription factor SMAD2 0.0283 0.0595 0.5234
Echinococcus multilocularis mothers against decapentaplegic 5 0.0019 0.0008 0.0008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0247 0.0515 0.0515
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0109 0.0101
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0024 0.0019 0.0164
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0024 0.0019 0.0019
Schistosoma mansoni alpha glucosidase 0.0038 0.0051 0.0043
Trypanosoma brucei glucosidase, putative 0.0038 0.0051 0.5
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0048 0.004
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0051 0.0611
Echinococcus granulosus Smad4 0.0019 0.0008 0.0008
Schistosoma mansoni RAR-like nuclear receptor 0.0024 0.0019 0.001
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0164
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0051 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0024 0.0019 0.0131
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0109 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0051 0.0098
Trichomonas vaginalis glucosylceramidase, putative 0.0302 0.0639 1
Schistosoma mansoni lamin 0.0032 0.0037 0.0029
Echinococcus multilocularis ecdysone induced protein 78C 0.0024 0.0019 0.0019
Brugia malayi MH2 domain containing protein 0.0283 0.0595 0.5218
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0413 0.0886 0.5
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0024 0.0019 0.0019
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0048 0.004
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0051 0.5
Echinococcus granulosus TGF beta signal transducer SmadC 0.0019 0.0008 0.0008
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0048 0.0048
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0019 0.0131
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.0407 0.6302
Onchocerca volvulus Glucosylceramidase homolog 0.0198 0.0407 0.6831
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0173 0.0351 0.3084
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0051 0.0611
Brugia malayi MH2 domain containing protein 0.0019 0.0008 0.0041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0024 0.0019 0.0164
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0024 0.0019 0.0019
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0051 0.0042
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.002 0.0012
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0032 0.0037 0.0325
Brugia malayi hypothetical protein 0.0038 0.0051 0.0413
Trichomonas vaginalis glucosylceramidase, putative 0.0302 0.0639 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0019 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0024 0.0019 0.0131
Brugia malayi Glycosyl hydrolases family 31 protein 0.0173 0.0351 0.3061
Schistosoma mansoni hypothetical protein 0.0122 0.0237 0.0229
Onchocerca volvulus 0.0094 0.0174 0.2728
Schistosoma mansoni steroid hormone receptor ad4bp 0.0024 0.0019 0.001
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0024 0.0019 0.0019
Brugia malayi nuclear receptor NHR-88 0.0024 0.0019 0.0131
Loa Loa (eye worm) hypothetical protein 0.0385 0.0824 0.7241
Onchocerca volvulus 0.01 0.0188 0.2982
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0109 0.0109
Trichomonas vaginalis glucosylceramidase, putative 0.0209 0.0431 0.6682
Onchocerca volvulus 0.0032 0.0037 0.0321
Brugia malayi photoreceptor-specific nuclear receptor 0.0024 0.0019 0.0131
Echinococcus granulosus lysosomal alpha glucosidase 0.0173 0.0351 0.0351
Loa Loa (eye worm) MH1 domain-containing protein 0.0019 0.0008 0.0074
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0025 0.002 0.002
Echinococcus multilocularis lysosomal alpha glucosidase 0.0173 0.0351 0.0351
Echinococcus granulosus neuropeptide receptor A26 0.2003 0.4426 0.4426
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0051 0.0417
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0024 0.0019 0.001
Schistosoma mansoni thyroid hormone receptor 0.0024 0.0019 0.001
Onchocerca volvulus 0.0279 0.0588 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0024 0.0019 0.0131
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0033 0.0033
Echinococcus granulosus survival motor neuron protein 1 0.0526 0.1138 0.1138
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0025 0.002 0.002
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0024 0.0019 0.0131
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.0407 0.6302
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0051 0.5
Trichomonas vaginalis glucosylceramidase, putative 0.0198 0.0407 0.6302
Brugia malayi Latrophilin receptor protein 2 0.0122 0.0237 0.2057
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0122 0.0237 0.2057
Trichomonas vaginalis glucosylceramidase, putative 0.0302 0.0639 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0051 0.0611
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0051 0.0051
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0034 0.0041 0.0041
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0051 0.0611
Brugia malayi hypothetical protein 0.0526 0.1138 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1906 0.4212 0.4212
Trichomonas vaginalis glucosylceramidase, putative 0.0302 0.0639 1
Brugia malayi latrophilin 2 splice variant baaae 0.0263 0.0552 0.4837
Trichomonas vaginalis glucosylceramidase, putative 0.0302 0.0639 1
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0051 0.0051
Schistosoma mansoni coup transcription factor 0.0024 0.0019 0.001
Brugia malayi intermediate filament protein 0.0032 0.0037 0.0292
Schistosoma mansoni hypothetical protein 0.0545 0.118 0.1172
Schistosoma mansoni hypothetical protein 0.0038 0.0051 0.0042
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0024 0.0019 0.0164
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0024 0.0019 0.0131
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0122 0.0237 0.0237
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0024 0.0019 0.0164
Schistosoma mansoni lamin 0.0032 0.0037 0.0029
Echinococcus granulosus lamin 0.0032 0.0037 0.0037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0019 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0024 0.0019 0.0131
Trichomonas vaginalis glucosylceramidase, putative 0.0302 0.0639 1
Echinococcus granulosus cpg binding protein 0.0099 0.0186 0.0186
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0051 0.0611
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0107 0.0205 0.1771
Brugia malayi MH2 domain containing protein 0.0019 0.0008 0.0041
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0025 0.002 0.002
Schistosoma mansoni intermediate filament proteins 0.0032 0.0037 0.0029
Schistosoma mansoni hypothetical protein 0.0545 0.118 0.1172
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0019 0.0019
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.1841 0.4065 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0164
Loa Loa (eye worm) MH2 domain-containing protein 0.0019 0.0008 0.0074
Schistosoma mansoni alpha-glucosidase 0.0149 0.0297 0.0289
Schistosoma mansoni hypothetical protein 0.0122 0.0237 0.0229
Brugia malayi Pre-SET motif family protein 0.0037 0.0048 0.0389
Echinococcus granulosus FTZ F1 alpha 0.0024 0.0019 0.0019
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0019 0.001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0247 0.0515 0.0515
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0024 0.0019 0.0019
Brugia malayi Pre-SET motif family protein 0.0246 0.0513 0.449
Brugia malayi Steroid receptor seven-up type 2 0.0024 0.0019 0.0131
Treponema pallidum replicative DNA helicase (dnaB) 0.0413 0.0886 0.5
Loa Loa (eye worm) hypothetical protein 0.0032 0.0037 0.0325
Brugia malayi Calcitonin receptor-like protein seb-1 0.0385 0.0824 0.7232
Echinococcus granulosus ecdysone induced protein 78C 0.0024 0.0019 0.0019
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0109 0.0101
Echinococcus multilocularis lamin dm0 0.0032 0.0037 0.0037
Loa Loa (eye worm) hypothetical protein 0.0024 0.0019 0.0164
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0024 0.0019 0.0019
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0122 0.0237 0.0237
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0385 0.0824 0.7232
Echinococcus granulosus geminin 0.0545 0.118 0.118

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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