Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.1359 | 0.1058 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0044 | 0.1539 | 0.1431 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.8814 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0195 | 0.0071 |
Brugia malayi | Bromodomain containing protein | 0.0081 | 0.3777 | 0.3958 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0054 | 0.212 | 0.2406 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1081 | 0.1227 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0076 | 0.3505 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.1646 | 0.1867 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1364 | 0.1548 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0064 | 0.2769 | 0.2677 |
Schistosoma mansoni | bromodomain containing protein | 0.0068 | 0.3005 | 0.2916 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0195 | 0.0222 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0163 | 0.8814 | 0.8799 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0044 | 0.1539 | 0.1431 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0076 | 0.3505 | 0.3422 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.212 | 0.1971 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0076 | 0.3505 | 0.3632 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0076 | 0.3505 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.212 | 0.1971 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.152 | 0.1724 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.1081 | 0.0724 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.3495 | 0.3966 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0076 | 0.3505 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.1203 | 0.1091 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0076 | 0.3505 | 0.3422 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0321 | 0.0198 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.1081 | 0.0968 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0076 | 0.3505 | 0.5 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0321 | 0.0198 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0064 | 0.2769 | 0.2677 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0076 | 0.3505 | 0.5 |
Echinococcus granulosus | muscleblind protein | 0.0163 | 0.8814 | 0.8799 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0076 | 0.3505 | 0.3422 |
Echinococcus multilocularis | muscleblind protein | 0.0163 | 0.8814 | 0.8799 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0076 | 0.3505 | 0.3976 |
Brugia malayi | Muscleblind-like protein | 0.0163 | 0.8814 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0321 | 0.0198 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.1203 | 0.1091 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.212 | 0.2406 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.8814 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.