TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 328.237 | Formula: C15H9F5N2O
H donors: 1 H acceptors: 1 LogP: 3.32 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: Fc1cccc(c1Cn1c(=O)[nH]c2c1cc(cc2)C(F)(F)F)F
InChi: 1S/C15H9F5N2O/c16-10-2-1-3-11(17)9(10)7-22-13-6-8(15(18,19)20)4-5-12(13)21-14(22)23/h1-6H,7H2,(H,21,23)
InChiKey: MSZLRJMCIIYHJP-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Human immunodeficiency virus 1	Reverse transcriptase	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Plasmodium yoelii	integrase-related	Get druggable targets OG5_139608	All targets in OG5_139608
Schistosoma mansoni	hypothetical protein	Get druggable targets OG5_139608	All targets in OG5_139608
Trypanosoma congolense	RNA helicase, putative	Get druggable targets OG5_139608	All targets in OG5_139608
Trypanosoma brucei	RNA helicase, putative	Get druggable targets OG5_139608	All targets in OG5_139608

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Dictyostelium discoideum	hypothetical protein	Reverse transcriptase	259 aa	245 aa	25.7 %
Dictyostelium discoideum	hypothetical protein	Reverse transcriptase	259 aa	226 aa	24.3 %
Echinococcus multilocularis	RNA directed DNA polymerase (reverse transcriptase)	Reverse transcriptase	259 aa	227 aa	26.4 %
Trypanosoma congolense	Retroviral aspartyl protease/Reverse transcriptase (RNA-dependent DNA polymerase)/RNase H, putative	Reverse transcriptase	259 aa	237 aa	29.1 %
Candida albicans	hypothetical protein	Reverse transcriptase	259 aa	223 aa	29.1 %
Dictyostelium discoideum	hypothetical protein	Reverse transcriptase	259 aa	222 aa	22.5 %
Candida albicans	ReverseTranscriptase similar to fruit fly Tom element	Reverse transcriptase	259 aa	244 aa	27.9 %
Echinococcus multilocularis	RNA directed DNA polymerase (reverse transcriptase)	Reverse transcriptase	259 aa	227 aa	26.4 %
Echinococcus multilocularis	RNA directed DNA polymerase (reverse transcriptase)	Reverse transcriptase	259 aa	208 aa	26.4 %
Candida albicans	polyprotein of retrotransposon Tca8	Reverse transcriptase	259 aa	238 aa	26.5 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	mixed lineage leukemia protein mll	0.0007	0.0095	0.0179
Brugia malayi	MH2 domain containing protein	0.0009	0.0167	0.0167
Echinococcus multilocularis	geminin	0.0167	0.5326	1
Loa Loa (eye worm)	PLK/PLK1 protein kinase	0.0095	0.2966	0.2966
Trypanosoma brucei	polo-like protein kinase	0.0095	0.2966	0.5112
Echinococcus granulosus	TGF beta signal transducer SmadC	0.0009	0.0167	0.0313
Toxoplasma gondii	aldehyde dehydrogenase	0.006	0.1822	1
Loa Loa (eye worm)	hypothetical protein	0.0004	0.0005	0.0005
Schistosoma mansoni	smad1 5 8 and	0.0009	0.0167	0.0167
Trichomonas vaginalis	chromodomain-helicase-DNA-binding protein, putative	0.0006	0.0075	0.007
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0006	0.0075	0.007
Schistosoma mansoni	TGF-beta signal transducer Smad2	0.0009	0.0167	0.0167
Brugia malayi	F/Y-rich N-terminus family protein	0.0009	0.0148	0.0148
Schistosoma mansoni	Smad4	0.0009	0.0167	0.0167
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0075	0.007
Echinococcus multilocularis	guanine nucleotide binding protein (G protein)	0.0004	0.0005	0.0009
Trypanosoma cruzi	polo-like protein kinase, putative	0.0095	0.2966	1
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.006	0.1822	0.533
Echinococcus granulosus	expressed protein	0.0004	0.0005	0.0009
Schistosoma mansoni	GTP-binding protein (I) alpha-1subunit gnai1	0.0004	0.0005	0.0005
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.2966	0.2963
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0075	0.007
Trichomonas vaginalis	chromodomain-helicase-DNA-binding protein, putative	0.0006	0.0075	0.007
Trichomonas vaginalis	helicase, putative	0.0006	0.0075	0.007
Schistosoma mansoni	cpg binding protein	0.0028	0.0791	0.0791
Echinococcus granulosus	cpg binding protein	0.003	0.0843	0.1584
Schistosoma mansoni	ap endonuclease	0.002	0.0516	0.0516
Schistosoma mansoni	smad1 5 8 and	0.0009	0.0167	0.0167
Loa Loa (eye worm)	heterotrimeric G protein alpha subunit	0.0004	0.0005	0.0005
Schistosoma mansoni	GTP-binding protein alpha subunit gna	0.0004	0.0005	0.0005
Echinococcus granulosus	smad	0.0009	0.0167	0.0313
Brugia malayi	MH1 domain containing protein	0.0005	0.0032	0.0032
Brugia malayi	MH1 domain containing protein	0.0009	0.0167	0.0167
Leishmania major	protein kinase, putative,polo-like protein kinase, putative	0.0095	0.2966	1
Schistosoma mansoni	GTP-binding protein (I) alpha subunit gnai	0.0004	0.0005	0.0005
Treponema pallidum	exodeoxyribonuclease (exoA)	0.002	0.0516	0.5
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0016	0.0396	0.0744
Loa Loa (eye worm)	MH2 domain-containing protein	0.0009	0.0167	0.0167
Echinococcus granulosus	guanine nucleotide binding protein G protein	0.0004	0.0005	0.0009
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.2966	0.2963
Schistosoma mansoni	GTP-binding protein alpha subunit gna	0.0004	0.0005	0.0005
Echinococcus granulosus	Smad4	0.0009	0.0167	0.0313
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0396	0.0396
Trichomonas vaginalis	CAMK family protein kinase	0.0047	0.14	0.1396
Trichomonas vaginalis	ap endonuclease, putative	0.002	0.0516	0.0512
Echinococcus granulosus	guanine nucleotide binding protein subunit	0.0004	0.0005	0.0009
Brugia malayi	guanine nucleotide-binding protein G(o), alpha subunit, putative	0.0004	0.0005	0.0005
Brugia malayi	guanine nucleotide-binding protein alpha-3 subunit, putative	0.0004	0.0005	0.0005
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.002	0.0516	0.0969
Schistosoma mansoni	GTP-binding protein (I) alpha-2 subunit gnai2	0.0004	0.0005	0.0005
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0075	0.007
Schistosoma mansoni	hypothetical protein	0.0167	0.5326	0.5326
Brugia malayi	Guanine nucleotide-binding protein alpha-6 subunit, putative	0.0004	0.0005	0.0005
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.006	0.1822	1
Echinococcus multilocularis	gtp binding protein (I) alpha 1subunit	0.0004	0.0005	0.0009
Schistosoma mansoni	GTP-binding protein alpha subunit	0.0004	0.0005	0.0005
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0099	0.3114	0.5846
Brugia malayi	Guanine nucleotide-binding protein alpha-3 subunit, putative	0.0004	0.0005	0.0005
Loa Loa (eye worm)	guanine nucleotide-binding protein alpha-6 subunit	0.0004	0.0005	0.0005
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0075	0.007
Loa Loa (eye worm)	hypothetical protein	0.0035	0.1012	0.1012
Brugia malayi	Latrophilin receptor protein 2	0.0016	0.0396	0.0396
Echinococcus multilocularis	cpg binding protein	0.003	0.0843	0.1584
Echinococcus multilocularis	GPCR, family 2	0.0016	0.0396	0.0744
Echinococcus multilocularis	serine:threonine protein kinase PLK1	0.0095	0.2966	0.5569
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0006	0.0075	0.007
Echinococcus multilocularis	mixed lineage leukemia protein mll	0.0007	0.0095	0.0179
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0006	0.0075	0.007
Brugia malayi	MH1 domain containing protein	0.0005	0.0032	0.0032
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0099	0.3114	0.3114
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.2966	0.2963
Echinococcus granulosus	geminin	0.0167	0.5326	1
Schistosoma mansoni	aldehyde dehydrogenase	0.006	0.1822	0.1822
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0007	0.0095	0.0179
Brugia malayi	serine/threonine-protein kinase plk-2	0.0095	0.2966	0.2966
Echinococcus multilocularis	guanine nucleotide binding protein subunit	0.0004	0.0005	0.0009
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0099	0.3114	0.3114
Schistosoma mansoni	smad1 5 8 and	0.0009	0.0167	0.0167
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.002	0.0516	0.0516
Echinococcus granulosus	guanine nucleotide binding protein G protein	0.0004	0.0005	0.0009
Brugia malayi	Guanine nucleotide-binding protein alpha-3 subunit, putative	0.0004	0.0005	0.0005
Schistosoma mansoni	GTP-binding protein (q) alpha-11 subunit gna11	0.0004	0.0005	0.0005
Loa Loa (eye worm)	hypothetical protein	0.0004	0.0005	0.0005
Trypanosoma cruzi	polo-like protein kinase, putative	0.0095	0.2966	1
Loa Loa (eye worm)	MH1 domain-containing protein	0.0009	0.0167	0.0167
Schistosoma mansoni	hypothetical protein	0.0016	0.0396	0.0396
Schistosoma mansoni	smad	0.0009	0.0167	0.0167
Onchocerca volvulus		0.0004	0.0005	0.0016
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0099	0.3114	0.3114
Echinococcus granulosus	gtp binding protein I alpha 1subunit	0.0004	0.0005	0.0009
Loa Loa (eye worm)	guanine nucleotide-binding protein alpha-12 subunit	0.0004	0.0005	0.0005
Trypanosoma brucei	RNA helicase, putative	0.0167	0.5309	1
Trichomonas vaginalis	ap endonuclease, putative	0.002	0.0516	0.0512
Echinococcus granulosus	GPCR family 2	0.0016	0.0396	0.0744
Loa Loa (eye worm)	hypothetical protein	0.0004	0.0005	0.0005
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0075	0.007
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0051	0.1543	0.1543
Schistosoma mansoni	kinase	0.0048	0.1441	0.1441
Echinococcus multilocularis	guanine nucleotide binding protein subunit	0.0004	0.0005	0.0009
Onchocerca volvulus	Serine\/threonine kinase homolog	0.0095	0.2966	1
Schistosoma mansoni	serine/threonine protein kinase	0.0095	0.2966	0.2966
Echinococcus granulosus	guanine nucleotide binding protein subunit	0.0004	0.0005	0.0009
Schistosoma mansoni	GTP-binding protein (q) alpha-11 subunit gna11	0.0004	0.0005	0.0005
Brugia malayi	MH1 domain containing protein	0.0009	0.0167	0.0167
Brugia malayi	exodeoxyribonuclease III family protein	0.002	0.0516	0.0516
Loa Loa (eye worm)	G protein alpha subunit 3	0.0004	0.0005	0.0005
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.2966	0.2963
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0099	0.3114	0.5846
Brugia malayi	hypothetical protein	0.0004	0.0005	0.0005
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0016	0.0396	0.0744
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.0009	0.0152	0.0285
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0051	0.1543	0.1543
Brugia malayi	latrophilin 2 splice variant baaae	0.0035	0.1012	0.1012
Loa Loa (eye worm)	hypothetical protein	0.0004	0.0005	0.0005
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0006	0.0075	0.007
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.006	0.1822	0.3421
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0075	0.007
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.002	0.0516	0.5
Echinococcus multilocularis	smad	0.0009	0.0167	0.0313
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0095	0.2966	1
Echinococcus granulosus	mothers against decapentaplegic 5	0.0009	0.0167	0.0313
Brugia malayi	guanine nucleotide-binding protein alpha-7 subunit, putative	0.0004	0.0005	0.0005
Schistosoma mansoni	cpg binding protein	0.003	0.0843	0.0843
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0016	0.0396	0.0744
Schistosoma mansoni	trimeric G-protein alpha o subunit	0.0004	0.0005	0.0005
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0007	0.0095	0.0179
Loa Loa (eye worm)	hypothetical protein	0.0004	0.0005	0.0005
Echinococcus multilocularis	mothers against decapentaplegic 5	0.0009	0.0167	0.0313
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0075	0.007
Loa Loa (eye worm)	hypothetical protein	0.0005	0.0032	0.0032
Schistosoma mansoni	ap endonuclease	0.002	0.0516	0.0516
Echinococcus multilocularis	Smad4	0.0009	0.0167	0.0313
Schistosoma mansoni	GTP-binding protein alpha subunit	0.0004	0.0005	0.0005
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0075	0.007
Loa Loa (eye worm)	GTP-binding regulatory protein alpha chain	0.0004	0.0005	0.0005
Schistosoma mansoni	hypothetical protein	0.0016	0.0396	0.0396
Brugia malayi	MH2 domain containing protein	0.0136	0.4291	0.4291
Brugia malayi	Guanine nucleotide-binding protein alpha-12 subunit, putative	0.0004	0.0005	0.0005
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0007	0.0095	0.0095
Onchocerca volvulus		0.0004	0.0005	0.0016
Giardia lamblia	Kinase, PLK	0.0095	0.2966	1
Loa Loa (eye worm)	hypothetical protein	0.0051	0.1543	0.1543
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0099	0.3114	0.3114
Schistosoma mansoni	hypothetical protein	0.0167	0.5309	0.5309
Mycobacterium ulcerans	aldehyde dehydrogenase	0.006	0.1822	0.1377
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0016	0.0396	0.0744
Loa Loa (eye worm)	histone methyltransferase	0.0009	0.0152	0.0152
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.002	0.0516	0.5
Schistosoma mansoni	hypothetical protein	0.0016	0.0396	0.0396
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0028	0.0791	0.0791
Schistosoma mansoni	aldehyde dehydrogenase	0.006	0.1822	0.1822
Echinococcus multilocularis	TGF beta signal transducer SmadC	0.0009	0.0167	0.0313
Mycobacterium ulcerans	aldehyde dehydrogenase	0.006	0.1822	0.1377
Onchocerca volvulus		0.0028	0.0791	0.2666
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.006	0.1828	0.1828
Schistosoma mansoni	cpg binding protein	0.003	0.0843	0.0843
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.002	0.0516	0.1727
Schistosoma mansoni	GTP-binding protein (I) alpha-2 subunit gnai2	0.0004	0.0005	0.0005
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.002	0.0516	0.5
Loa Loa (eye worm)	MH2 domain-containing protein	0.0136	0.4291	0.4291
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.2966	0.2963
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0016	0.0396	0.0396
Brugia malayi	Smad1	0.0009	0.0167	0.0167
Brugia malayi	MH2 domain containing protein	0.0009	0.0167	0.0167
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0099	0.3114	0.5846
Trichomonas vaginalis	conserved hypothetical protein	0.0006	0.0075	0.007
Brugia malayi	GTP-binding regulatory protein alpha chain - starfish, putative	0.0004	0.0005	0.0005
Onchocerca volvulus		0.0004	0.0005	0.0016
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0051	0.1543	0.1543
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.0009	0.0152	0.0285
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.006	0.1822	0.3421
Echinococcus multilocularis	guanine nucleotide binding protein (G protein)	0.0004	0.0005	0.0009
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.2966	0.2963
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.2966	0.2963
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0099	0.3114	0.5846
Brugia malayi	guanine nucleotide-binding protein G-o protein alpha subunit	0.0004	0.0005	0.0005
Schistosoma mansoni	hypothetical protein	0.0016	0.0396	0.0396
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.002	0.0516	0.0969
Mycobacterium ulcerans	aldehyde dehydrogenase	0.006	0.1822	0.1377
Brugia malayi	CXXC zinc finger family protein	0.0028	0.0791	0.0791
Loa Loa (eye worm)	nuclear factor I	0.0005	0.0032	0.0032
Schistosoma mansoni	GTP-binding protein (I) alpha-2 subunit gnai2	0.0004	0.0005	0.0005
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0006	0.0075	0.007
Schistosoma mansoni	GTP-binding protein (I) alpha-1subunit gnai1	0.0004	0.0005	0.0005
Loa Loa (eye worm)	Smad1	0.0009	0.0167	0.0167
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0099	0.3114	0.3114
Trichomonas vaginalis	chromodomain helicase DNA binding protein, putative	0.0006	0.0075	0.007
Schistosoma mansoni	hypothetical protein	0.0167	0.5326	0.5326
Schistosoma mansoni	hypothetical protein	0.0035	0.1012	0.1012
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0016	0.0396	0.0396
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0054	0.1619	0.8443
Brugia malayi	G-protein alpha subunit	0.0004	0.0005	0.0005
Echinococcus multilocularis	expressed protein	0.0004	0.0005	0.0009
Trichomonas vaginalis	CAMK family protein kinase	0.0047	0.14	0.1396
Echinococcus granulosus	serine:threonine protein kinase PLK1	0.0095	0.2966	0.5569
Loa Loa (eye worm)	transcription factor SMAD2	0.0136	0.4291	0.4291

Activities

Activity type	Activity value	Assay description	Source	Reference
CC50 (ADMET)	> 424 uM	Cytotoxicity against human MT4 cells	ChEMBL.	18585918
IC50 (binding)	= 0.017 uM	Inhibition of HIV1 reverse transcriptase RNA-dependent DNA polymerase activity assessed as incorporation of radioactive dTTP into poly(rA)/oligo(DT)	ChEMBL.	18585918

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL450764

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1178871