Detailed information for compound 1179824

Basic information

Technical information
  • TDR Targets ID: 1179824
  • Name: N-[[3,5-dichloro-2-fluoro-4-(1,1,2,3,3,3-hexa fluoropropoxy)phenyl]carbamoyl]-2,6-difluorob enzamide
  • MW: 529.141 | Formula: C17H7Cl2F9N2O3
  • H donors: 2 H acceptors: 2 LogP: 6.74 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C(NC(=O)c1c(F)cccc1F)Nc1cc(Cl)c(c(c1F)Cl)OC(C(C(F)(F)F)F)(F)F
  • InChi: 1S/C17H7Cl2F9N2O3/c18-5-4-8(29-15(32)30-13(31)9-6(20)2-1-3-7(9)21)11(22)10(19)12(5)33-17(27,28)14(23)16(24,25)26/h1-4,14H,(H2,29,30,31,32)
  • InChiKey: YTYGAJLZOJPJGH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[[3,5-dichloro-2-fluoro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl]-2,6-difluoro-benzamide
  • N-[[[3,5-dichloro-2-fluoro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino]-oxomethyl]-2,6-difluorobenzamide
  • 121451-02-3
  • CHEBI:39386
  • N-({[3,5-dichloro-2-fluoro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino}carbonyl)-2,6-difluorobenzamide
  • N-{[3,5-dichloro-2-fluoro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl}-2,6-difluorobenzamide
  • Noviflumuron
  • NCGC00163940-01

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) glutaminase 2 0.0282 0.9012 1
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0013 0.0015 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0015 0.0015
Trypanosoma cruzi ISWI complex protein 0.0016 0.0114 0.0114
Plasmodium falciparum small ubiquitin-related modifier 0.0032 0.0645 0.1182
Loa Loa (eye worm) hypothetical protein 0.0044 0.1057 0.1173
Leishmania major small ubiquitin protein, putative 0.0032 0.0645 0.0645
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0918 0.0918
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0098 0.2879 0.5265
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0918 0.0918
Brugia malayi Bromodomain containing protein 0.0032 0.0674 0.0748
Echinococcus granulosus dna polymerase kappa 0.004 0.0918 0.166
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.087 0.0965
Entamoeba histolytica ubiquitin like protein 0.0032 0.0645 0.1158
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0918 0.1018
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.4515 0.4515
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0098 0.2879 0.5265
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0592 0.0657
Loa Loa (eye worm) hypothetical protein 0.0013 0.001 0.0011
Leishmania major hypothetical protein, conserved 0.0013 0.0015 0.0015
Giardia lamblia DINP protein human, muc B family 0.004 0.0918 0.1682
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0196 0.0218
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0918 0.0918
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0175 0.5455 0.5455
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0592 0.1061
Loa Loa (eye worm) hypothetical protein 0.0073 0.2025 0.2247
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0048 0.1204 0.2186
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0804 0.145
Plasmodium vivax SET domain protein, putative 0.0031 0.0616 0.113
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.1204 0.1336
Trypanosoma brucei unspecified product 0.0027 0.0505 0.0505
Schistosoma mansoni caspase-7 (C14 family) 0.0032 0.0652 0.0724
Trypanosoma brucei phosphoglycerate kinase 0.0175 0.5455 0.5455
Echinococcus multilocularis apoptotic protease activating factor 1 0.0032 0.0653 0.1172
Leishmania major phosphoglycerate kinase C, glycosomal 0.0175 0.5455 0.5455
Leishmania major DNA polymerase kappa, putative 0.004 0.0918 0.0918
Schistosoma mansoni hypothetical protein 0.0016 0.0114 0.0127
Echinococcus multilocularis dna polymerase kappa 0.004 0.0918 0.166
Plasmodium vivax small ubiquitin-related modifier, putative 0.0032 0.0645 0.1182
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0064 0.1741 0.1741
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0175 0.5455 0.6046
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0175 0.5455 0.5455
Echinococcus granulosus G protein coupled receptor kinase 1 0.0086 0.245 0.4476
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.4515 0.4515
Trichomonas vaginalis set domain proteins, putative 0.0244 0.7754 0.8602
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0039 0.0878 0.161
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0986 0.1785
Trypanosoma brucei phosphoglycerate kinase 0.0175 0.5455 0.5455
Brugia malayi Phosphoglycerate kinase 0.0064 0.1741 0.1932
Loa Loa (eye worm) hypothetical protein 0.004 0.091 0.101
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.1662 0.1845
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.1645 0.2997
Echinococcus multilocularis peregrin 0.0032 0.0674 0.1211
Brugia malayi glutaminase DH11.1 0.0282 0.9012 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0652 0.0724
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0505 0.0505
Toxoplasma gondii small ubiquitin family modifier, putative 0.0032 0.0645 0.1182
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0592 0.1061
Onchocerca volvulus 0.0244 0.7754 1
Plasmodium falciparum phd finger protein, putative 0.003 0.0592 0.1086
Trypanosoma brucei phosphoglycerate kinase 0.0064 0.1741 0.1741
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0592 0.1086
Mycobacterium ulcerans hypothetical protein 0.0164 0.5072 0.5628
Chlamydia trachomatis phosphoglycerate kinase 0.0175 0.5455 0.5
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0918 0.1018
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.1645 0.2997
Onchocerca volvulus 0.0031 0.0616 0.0034
Entamoeba histolytica phosphoglycerate kinase, putative 0.0175 0.5455 1
Echinococcus granulosus phosphoglycerate kinase 1 0.0175 0.5455 1
Schistosoma mansoni phosphoglycerate kinase 0.0175 0.5455 0.6053
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0505 0.0505
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0645 0.07
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0918 0.1018
Brugia malayi jmjC domain containing protein 0.0038 0.087 0.0965
Trypanosoma brucei small ubiquitin-related modifier 0.0032 0.0645 0.0645
Brugia malayi ImpB/MucB/SamB family protein 0.0066 0.1796 0.1993
Trypanosoma brucei phosphoglycerate kinase, putative 0.0064 0.1741 0.1741
Brugia malayi F/Y-rich N-terminus family protein 0.0013 0.0019 0.0021
Schistosoma mansoni hypothetical protein 0.0032 0.0653 0.0724
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.2781 0.3085
Echinococcus granulosus beta-adrenergic receptor kinase 0.0095 0.2781 0.5084
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0298 0.0331
Trypanosoma cruzi 3-phosphoglycerate kinase, glycosomal 0.0064 0.1741 0.1741
Echinococcus granulosus caspase 2 0.0032 0.0652 0.1172
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.087 0.1571
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0918 0.0918
Loa Loa (eye worm) hypothetical protein 0.0048 0.1204 0.1336
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0013 0.0015 0.0027
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.4515 0.4515
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.2781 0.3085
Trichomonas vaginalis phosphoglycerate kinase, putative 0.0175 0.5455 0.6046
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0918 0.0918
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0918 0.166
Echinococcus granulosus histone lysine methyltransferase setb 0.0048 0.1204 0.2186
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0064 0.1741 0.1741
Giardia lamblia Sentrin 0.0032 0.0645 0.1182
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0986 0.1785
Brugia malayi PHD-finger family protein 0.003 0.0592 0.0657
Plasmodium falciparum phosphoglycerate kinase 0.0175 0.5455 1
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0918 0.0918
Schistosoma mansoni bromodomain containing protein 0.0065 0.1769 0.1963
Brugia malayi Bromodomain containing protein 0.0077 0.2173 0.2411
Loa Loa (eye worm) hypothetical protein 0.003 0.0592 0.0657
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0918 0.0918
Trypanosoma cruzi small ubiquitin protein, putative 0.0032 0.0645 0.0645
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0918 0.0918
Echinococcus multilocularis G protein coupled receptor kinase 1 0.0086 0.245 0.4476
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0016
Echinococcus multilocularis caspase 2 0.0032 0.0652 0.1172
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0364 0.0642
Schistosoma mansoni phosphoglycerate kinase 0.0175 0.5455 0.6053
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0918 0.1018
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0918 0.1018
Loa Loa (eye worm) glutaminase 0.0282 0.9012 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0616 0.1106
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0878 0.0878
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.0015 0.0016
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0826 0.1491
Trichomonas vaginalis glutaminase, putative 0.0282 0.9012 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0918 0.0918
Schistosoma mansoni DNA polymerase eta 0.0066 0.1796 0.1993
Trypanosoma brucei unspecified product 0.004 0.0918 0.0918
Schistosoma mansoni hypothetical protein 0.0021 0.0298 0.0331
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.1051 0.1051
Mycobacterium tuberculosis Conserved hypothetical protein 0.0164 0.5072 0.9156
Plasmodium vivax phosphoglycerate kinase, putative 0.0175 0.5455 1
Brugia malayi Pre-SET motif family protein 0.0214 0.6763 0.7504
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0013 0.0015 0.0016
Brugia malayi Bromodomain containing protein 0.0039 0.0907 0.1007
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0505 0.0505
Brugia malayi hypothetical protein 0.0032 0.0652 0.0724
Leishmania major DNA polymerase eta, putative 0.0066 0.1796 0.1796
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.1051 0.1051
Leishmania major DNA polymerase eta, putative 0.0039 0.0878 0.0878
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0364 0.0642
Echinococcus granulosus methyl CpG binding domain protein 2 0.0018 0.0175 0.0294
Echinococcus multilocularis dna polymerase eta 0.0066 0.1796 0.3274
Brugia malayi Ubiquitin-like protein SMT3 0.0032 0.0645 0.0715
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0918 0.0918
Brugia malayi Phosphoglycerate kinase 0.0175 0.5455 0.6053
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0013 0.0015 0.0027
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.0032 0.0645 0.0715
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0616 0.0684
Trypanosoma brucei DNA polymerase eta, putative 0.0066 0.1796 0.1796
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0013 0.0015 0.0015
Schistosoma mansoni zinc finger protein 0.0016 0.0114 0.0127
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0175 0.0194
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0018 0.0175 0.0294
Brugia malayi jmjC domain containing protein 0.0098 0.2879 0.3195
Onchocerca volvulus 0.0032 0.0652 0.0084
Plasmodium vivax hypothetical protein, conserved 0.003 0.0592 0.1086
Echinococcus granulosus zinc finger protein 0.002 0.0262 0.0454
Schistosoma mansoni zinc finger protein 0.002 0.0262 0.0291
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0918 0.166
Echinococcus multilocularis phosphoglycerate kinase 1 0.0175 0.5455 1
Giardia lamblia Phosphoglycerate kinase 0.0175 0.5455 1
Mycobacterium tuberculosis Probable phosphoglycerate kinase Pgk 0.0175 0.5455 1
Schistosoma mansoni glutaminase 0.0282 0.9012 1
Echinococcus granulosus dna polymerase eta 0.0066 0.1796 0.3274
Loa Loa (eye worm) hypothetical protein 0.0042 0.0992 0.11
Brugia malayi PHD-finger family protein 0.0026 0.0446 0.0495
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0918 0.0918
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.1051 0.1051
Onchocerca volvulus Cell death protein 3 homolog 0.0032 0.0652 0.0084
Mycobacterium ulcerans phosphoglycerate kinase 0.0175 0.5455 0.6053
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0616 0.113
Wolbachia endosymbiont of Brugia malayi phosphoglycerate kinase 0.0175 0.5455 0.5
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.087 0.0965
Trypanosoma cruzi ISWI complex protein 0.0016 0.0114 0.0114
Schistosoma mansoni hypothetical protein 0.0013 0.001 0.0011
Trypanosoma cruzi small ubiquitin protein, putative 0.0032 0.0645 0.0645
Trypanosoma brucei ISWI complex protein 0.0016 0.0114 0.0114
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0918 0.166
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0918 0.1004
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0592 0.0657
Echinococcus multilocularis Small ubiquitin modifier 2 0.0032 0.0645 0.1158
Loa Loa (eye worm) SMO-1 protein 0.0032 0.0645 0.0715
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.087 0.0965
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.1371 0.1371
Trypanosoma cruzi DNA polymerase eta, putative 0.0066 0.1796 0.1796
Echinococcus granulosus apoptotic protease activating factor 1 0.0032 0.0653 0.1172
Leishmania major phosphoglycerate kinase B, cytosolic 0.0175 0.5455 0.5455
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0592 0.1086
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0364 0.0404
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0918 0.0918
Loa Loa (eye worm) hypothetical protein 0.0052 0.131 0.1454
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0918 0.0918
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0048 0.1204 0.1336
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0918 0.0918
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0064 0.1741 0.1741
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0918 0.1004
Treponema pallidum phosphoglycerate kinase 0.0175 0.5455 0.5
Trypanosoma brucei unspecified product 0.0027 0.0505 0.0505
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0918 0.0918
Echinococcus granulosus Small ubiquitin modifier 2 0.0032 0.0645 0.1158
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0064 0.1741 0.1741
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0095 0.2781 0.3085
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0013 0.0015 0.0027
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0013 0.0015 0.0027
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0214 0.6763 0.7504
Toxoplasma gondii phosphoglycerate kinase PGKI 0.0175 0.5455 1
Leishmania major hypothetical protein, conserved 0.0016 0.0114 0.0114
Trypanosoma cruzi phosphoglycerate kinase, putative 0.0064 0.1741 0.1741
Giardia lamblia PHD finger protein 15 0.003 0.0592 0.1086
Mycobacterium ulcerans glutaminase 0.0282 0.9012 1
Brugia malayi Pre-SET motif family protein 0.0031 0.0616 0.0684
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0175 0.0194
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0918 0.0918
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0616 0.0684
Toxoplasma gondii phosphoglycerate kinase PGKII 0.0175 0.5455 1
Schistosoma mansoni jumonji domain containing protein 0.0078 0.2203 0.2444
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.1051 0.1051
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0013 0.0015 0.0016
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0918 0.0918
Echinococcus multilocularis beta adrenergic receptor kinase 0.0095 0.2781 0.5084
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0918 0.0918
Schistosoma mansoni hypothetical protein 0.003 0.0592 0.0657
Echinococcus granulosus peregrin 0.0032 0.0674 0.1211
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0826 0.1491
Brugia malayi Cell death protein 3 precursor 0.0032 0.0652 0.0724
Toxoplasma gondii hypothetical protein 0.005 0.1266 0.2322
Mycobacterium leprae Probable phosphoglycerate kinase Pgk 0.0175 0.5455 0.5
Loa Loa (eye worm) hypothetical protein 0.0066 0.1796 0.1993
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0578 0.1036
Loa Loa (eye worm) hypothetical protein 0.0032 0.0652 0.0724
Loa Loa (eye worm) hypothetical protein 0.0175 0.5455 0.6053
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0918 0.1018
Echinococcus multilocularis zinc finger protein 0.002 0.0262 0.0454

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of glucocorticoid receptor signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of glucocorticoid receptor signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 30.6379 uM PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 68.5896 uM PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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