Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0114 | 0.0379 |
Mycobacterium ulcerans | hypothetical protein | 0.0077 | 0.0064 | 0.0759 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0039 | 0.0311 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0149 | 0.0164 | 0.0586 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.0301 | 0.1003 |
Brugia malayi | hypothetical protein | 0.0248 | 0.0301 | 0.1004 |
Onchocerca volvulus | 0.0078 | 0.0066 | 0.0342 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0326 | 0.0409 | 0.1461 |
Loa Loa (eye worm) | hypothetical protein | 0.0453 | 0.0586 | 0.1954 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0191 | 0.0221 | 0.0737 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0036 | 0.0006 | 0.001 |
Brugia malayi | MH1 domain containing protein | 0.0149 | 0.0164 | 0.0547 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0077 | 0.0064 | 0.0759 |
Brugia malayi | AMP-binding enzyme family protein | 0.0077 | 0.0064 | 0.0214 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0149 | 0.0164 | 0.0163 |
Schistosoma mansoni | rab6-interacting | 0.0078 | 0.0066 | 0.0234 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0038 | 0.0009 | 0.0016 |
Plasmodium vivax | glutathione reductase, putative | 0.0087 | 0.0077 | 0.1207 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.2191 | 0.2998 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.2191 | 0.2998 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0077 | 0.0064 | 0.0759 |
Echinococcus multilocularis | transcription factor eb | 0.0107 | 0.0106 | 0.0105 |
Echinococcus multilocularis | Smad4 | 0.0149 | 0.0164 | 0.0163 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0246 | 0.0298 | 0.0996 |
Leishmania major | hypothetical protein, conserved | 0.0453 | 0.0586 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.012 | 0.0123 | 0.0441 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0016 | 0.0015 |
Echinococcus granulosus | Smad4 | 0.0149 | 0.0164 | 0.0302 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0077 | 0.0064 | 0.0759 |
Onchocerca volvulus | 0.0077 | 0.0064 | 0.0334 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0164 | 0.0184 | 0.3031 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0058 | 0.0037 | 0.0279 |
Loa Loa (eye worm) | hypothetical protein | 0.0602 | 0.0793 | 0.2643 |
Mycobacterium tuberculosis | Conserved protein | 0.0453 | 0.0586 | 0.1427 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0453 | 0.0586 | 0.2094 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0155 | 0.0172 | 0.0615 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.005 | 0.0027 | 0.0026 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0014 | 0.0049 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0113 | 0.0114 | 0.0642 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0047 | 0.0022 | 0.0368 |
Mycobacterium leprae | conserved hypothetical protein | 0.0453 | 0.0586 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0154 | 0.0171 | 0.061 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0047 | 0.0022 | 0.0368 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0191 | 0.0221 | 0.0221 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0038 | 0.0009 | 0.0008 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0133 | 0.0141 | 0.2404 |
Brugia malayi | Sodium:solute symporter family protein | 0.0038 | 0.0009 | 0.0031 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0113 | 0.0114 | 0.1823 |
Schistosoma mansoni | Smad4 | 0.0067 | 0.0049 | 0.0176 |
Plasmodium vivax | hypothetical protein, conserved | 0.0095 | 0.0089 | 0.1415 |
Leishmania major | cytochrome p450-like protein | 0.0046 | 0.0021 | 0.0213 |
Loa Loa (eye worm) | nuclear factor I | 0.0083 | 0.0071 | 0.0236 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.0027 | 0.0308 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0099 | 0.0094 | 0.4077 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.005 | 0.0027 | 0.0455 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0191 | 0.0221 | 0.0738 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0453 | 0.0586 | 0.2094 |
Brugia malayi | Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog | 0.0532 | 0.0695 | 0.2318 |
Echinococcus multilocularis | musashi | 0.0054 | 0.0031 | 0.0031 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0113 | 0.0114 | 0.5018 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0191 | 0.0221 | 0.0738 |
Schistosoma mansoni | jumonji domain containing protein | 0.0248 | 0.0301 | 0.1075 |
Loa Loa (eye worm) | potassium voltage-gated channel subfamily Q member 5 | 0.0063 | 0.0044 | 0.0145 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.005 | 0.0027 | 0.0308 |
Echinococcus granulosus | neuropeptide s receptor | 0.0487 | 0.0633 | 0.1168 |
Brugia malayi | beta-lactamase family protein | 0.0453 | 0.0586 | 0.1955 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.012 | 0.0123 | 0.0441 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0047 | 0.0022 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0044 | 0.0145 |
Mycobacterium ulcerans | hypothetical protein | 0.0453 | 0.0586 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0037 | 0.0122 |
Schistosoma mansoni | inositol transporter | 0.0038 | 0.0009 | 0.0033 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0047 | 0.0022 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0037 | 0.0122 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0115 | 0.0117 | 0.0116 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0038 | 0.0009 | 0.016 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0016 | 0.0051 |
Echinococcus granulosus | sodium:glucose cotransporter | 0.0038 | 0.0009 | 0.0016 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0047 | 0.0022 | 0.0219 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0014 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0037 | 0.0122 |
Schistosoma mansoni | alpha-glucosidase | 0.0146 | 0.0159 | 0.0568 |
Echinococcus granulosus | lamin | 0.0054 | 0.0031 | 0.0057 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0047 | 0.0022 | 0.007 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.0089 | 0.0318 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0164 | 0.0184 | 0.3147 |
Schistosoma mansoni | smad1 5 8 and | 0.0149 | 0.0164 | 0.0586 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0346 | 0.0437 | 0.741 |
Loa Loa (eye worm) | glutathione reductase | 0.0087 | 0.0077 | 0.0255 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0149 | 0.0164 | 0.0545 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0113 | 0.0114 | 0.1948 |
Brugia malayi | Thioredoxin reductase | 0.0087 | 0.0077 | 0.0257 |
Toxoplasma gondii | thioredoxin reductase | 0.0087 | 0.0077 | 0.1313 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0149 | 0.0164 | 0.0545 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0077 | 0.0064 | 0.0107 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0014 | 0.0049 |
Brugia malayi | jmjC domain containing protein | 0.012 | 0.0123 | 0.0412 |
Loa Loa (eye worm) | hypothetical protein | 0.0453 | 0.0586 | 0.1954 |
Schistosoma mansoni | Smad4 | 0.0067 | 0.0049 | 0.0176 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0016 | 0.0028 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0149 | 0.0164 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.0301 | 0.1003 |
Schistosoma mansoni | rab6-interacting | 0.0078 | 0.0066 | 0.0234 |
Toxoplasma gondii | ABC1 family protein | 0.0453 | 0.0586 | 1 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0067 | 0.0049 | 0.0244 |
Brugia malayi | intermediate filament protein | 0.0054 | 0.0031 | 0.0104 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0346 | 0.0437 | 0.741 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0087 | 0.0078 | 0.0077 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0016 | 0.0057 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0067 | 0.0049 | 0.0049 |
Schistosoma mansoni | inositol transporter | 0.0038 | 0.0009 | 0.0033 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0113 | 0.0114 | 0.0114 |
Mycobacterium leprae | Probable lipase LipE | 0.0453 | 0.0586 | 1 |
Echinococcus granulosus | jumonji domain containing protein | 0.0133 | 0.0141 | 0.0259 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0515 | 0.0671 | 0.404 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0155 | 0.0172 | 0.0317 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0046 | 0.0021 | 0.0069 |
Leishmania major | hypothetical protein, conserved | 0.0133 | 0.0141 | 0.2286 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0326 | 0.0409 | 0.1461 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.0039 | 0.0517 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0062 | 0.0043 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0064 | 0.0212 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0084 | 0.0073 | 0.0241 |
Brugia malayi | Doublecortin family protein | 0.0078 | 0.0066 | 0.0219 |
Onchocerca volvulus | 0.0098 | 0.0093 | 0.0508 | |
Echinococcus multilocularis | lamin | 0.0054 | 0.0031 | 0.0031 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0058 | 0.0037 | 0.2232 |
Brugia malayi | GH02984p | 0.0344 | 0.0434 | 0.1447 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0078 | 0.0066 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.0071 | 0.0236 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0198 | 0.0231 | 0.3197 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0602 | 0.0793 | 0.2643 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0113 | 0.0114 | 0.1823 |
Echinococcus multilocularis | peregrin | 0.0095 | 0.0089 | 0.0089 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0067 | 0.0049 | 0.009 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0077 | 0.0064 | 0.0107 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0133 | 0.0141 | 0.014 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0077 | 0.0064 | 0.0955 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0029 | 0.0096 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0037 | 0.0122 |
Brugia malayi | Smad1 | 0.0149 | 0.0164 | 0.0547 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0047 | 0.0022 | 0.1084 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0326 | 0.0409 | 0.1461 |
Loa Loa (eye worm) | hypothetical protein | 0.0453 | 0.0586 | 0.1954 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0059 | 0.0039 | 0.0039 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0133 | 0.0141 | 0.2286 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0183 | 0.0211 | 0.0753 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0198 | 0.0231 | 0.0529 |
Echinococcus multilocularis | potassium voltage gated channel subfamily KQT | 0.0063 | 0.0044 | 0.0044 |
Brugia malayi | hypothetical protein | 0.0078 | 0.0066 | 0.0219 |
Echinococcus granulosus | solute carrier family 5 | 0.0038 | 0.0009 | 0.0016 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0038 | 0.0009 | 0.0016 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0453 | 0.0586 | 0.1427 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0326 | 0.0409 | 0.1364 |
Toxoplasma gondii | hypothetical protein | 0.0056 | 0.0034 | 0.0583 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.0039 | 0.0043 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0198 | 0.0231 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0037 | 0.0122 |
Schistosoma mansoni | smad | 0.0067 | 0.0049 | 0.0176 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0113 | 0.0114 | 0.0114 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.0039 | 0.0662 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0113 | 0.0114 | 0.0642 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0058 | 0.0037 | 0.5 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0113 | 0.0114 | 0.0114 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0087 | 0.0077 | 0.1179 |
Schistosoma mansoni | smad1 5 8 and | 0.0149 | 0.0164 | 0.0586 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0133 | 0.0141 | 0.2311 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0036 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0576 | 0.0755 | 0.2519 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0016 | 0.0051 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0453 | 0.0586 | 0.1082 |
Onchocerca volvulus | 0.0453 | 0.0586 | 0.3517 | |
Echinococcus granulosus | lysine specific demethylase 5A | 0.012 | 0.0123 | 0.0227 |
Loa Loa (eye worm) | beta-lactamase | 0.0453 | 0.0586 | 0.1954 |
Brugia malayi | glutathione reductase | 0.0087 | 0.0077 | 0.0257 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0077 | 0.0064 | 0.2629 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0457 | 0.059 | 0.1968 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0014 | 0.0049 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.005 | 0.0027 | 0.0048 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0453 | 0.0586 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.1207 | 0.1632 | 0.5444 |
Echinococcus granulosus | smad | 0.0149 | 0.0164 | 0.0302 |
Schistosoma mansoni | Smad4 | 0.0149 | 0.0164 | 0.0586 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0113 | 0.0114 | 1 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.0024 | 0.0024 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0067 | 0.0049 | 0.009 |
Brugia malayi | MH2 domain containing protein | 0.2191 | 0.2998 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0469 | 0.0607 | 0.1121 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.005 | 0.0027 | 0.0026 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0453 | 0.0586 | 0.3519 |
Onchocerca volvulus | Huntingtin homolog | 0.0248 | 0.0301 | 0.1779 |
Brugia malayi | MAP kinase sur-1 | 0.005 | 0.0027 | 0.0089 |
Echinococcus multilocularis | dnaJ subfamily B | 0.1191 | 0.1609 | 0.1609 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0453 | 0.0586 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.0246 | 0.0298 | 0.1066 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0046 | 0.0021 | 0.0069 |
Brugia malayi | hypothetical protein | 0.1207 | 0.1632 | 0.5445 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.005 | 0.0027 | 0.0308 |
Schistosoma mansoni | cpg binding protein | 0.0088 | 0.0079 | 0.0284 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.1207 | 0.1632 | 0.3014 |
Echinococcus granulosus | lamin dm0 | 0.0054 | 0.0031 | 0.0057 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0099 | 0.0094 | 0.0174 |
Echinococcus granulosus | RUN | 0.0078 | 0.0066 | 0.012 |
Echinococcus granulosus | dnaJ subfamily B | 0.1191 | 0.1609 | 0.2972 |
Mycobacterium ulcerans | hypothetical protein | 0.0182 | 0.021 | 0.3334 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0344 | 0.0434 | 0.0433 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0412 | 0.0528 | 0.1762 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0326 | 0.0409 | 0.0408 |
Echinococcus granulosus | expressed conserved protein | 0.0093 | 0.0086 | 0.0158 |
Entamoeba histolytica | hypothetical protein | 0.0189 | 0.0219 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0046 | 0.0021 | 0.0213 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0047 | 0.0022 | 0.0219 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.2048 | 0.2799 | 0.2799 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.022 | 0.0262 | 0.0607 |
Mycobacterium ulcerans | lipase LipD | 0.0453 | 0.0586 | 1 |
Onchocerca volvulus | Alhambra homolog | 0.0095 | 0.0089 | 0.0486 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0149 | 0.0164 | 0.0302 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.005 | 0.0027 | 0.0455 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0191 | 0.0221 | 0.0221 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.0027 | 0.0108 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0487 | 0.0633 | 0.0633 |
Giardia lamblia | PHD finger protein 15 | 0.0095 | 0.0089 | 0.7127 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0038 | 0.0009 | 0.0009 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0453 | 0.0586 | 0.1954 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0066 | 0.0234 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.005 | 0.0027 | 0.0087 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0095 | 0.0089 | 0.0318 |
Schistosoma mansoni | hypothetical protein | 0.0059 | 0.0039 | 0.0141 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0078 | 0.0066 | 0.0065 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0113 | 0.0114 | 0.021 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0113 | 0.0114 | 0.0408 |
Echinococcus granulosus | mitogen activated protein kinase | 0.005 | 0.0027 | 0.0048 |
Brugia malayi | hypothetical protein | 0.0189 | 0.0219 | 0.0729 |
Schistosoma mansoni | alpha glucosidase | 0.0038 | 0.0009 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0066 | 0.0217 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0077 | 0.0064 | 0.0955 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0064 | 0.0212 |
Onchocerca volvulus | 0.0246 | 0.0298 | 0.1763 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0039 | 0.0139 |
Entamoeba histolytica | hypothetical protein | 0.0189 | 0.0219 | 1 |
Echinococcus multilocularis | RUN | 0.0078 | 0.0066 | 0.0065 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0046 | 0.0021 | 0.0069 |
Brugia malayi | hypothetical protein | 0.0086 | 0.0076 | 0.0252 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0047 | 0.0022 | 0.0021 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0154 | 0.0171 | 0.017 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0576 | 0.0755 | 0.2699 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.0221 | 0.079 |
Loa Loa (eye worm) | intermediate filament protein | 0.0054 | 0.0031 | 0.0102 |
Onchocerca volvulus | 0.0054 | 0.0031 | 0.0133 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0049 | 0.0024 | 0.0265 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.022 | 0.0262 | 0.0607 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0095 | 0.0089 | 0.0164 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0077 | 0.0064 | 0.2629 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0453 | 0.0586 | 0.1427 |
Mycobacterium ulcerans | beta-lactamase | 0.0453 | 0.0586 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0326 | 0.0409 | 0.1363 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.005 | 0.0027 | 0.0308 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0069 | 0.0052 | 0.0172 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0047 | 0.0022 | 0.0368 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0047 | 0.0022 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0094 | 0.0313 |
Brugia malayi | AMP-binding enzyme family protein | 0.0077 | 0.0064 | 0.0214 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0009 | 0.0152 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0059 | 0.0039 | 0.0072 |
Schistosoma mansoni | cpg binding protein | 0.0084 | 0.0073 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0089 | 0.0295 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0101 | 0.0097 | 0.0345 |
Schistosoma mansoni | hypothetical protein | 0.0666 | 0.0881 | 0.3146 |
Loa Loa (eye worm) | hypothetical protein | 0.0191 | 0.0221 | 0.0737 |
Loa Loa (eye worm) | helix-loop-helix DNA-binding domain-containing protein | 0.0107 | 0.0105 | 0.0349 |
Brugia malayi | Pre-SET motif family protein | 0.0155 | 0.0172 | 0.0575 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0058 | 0.0037 | 0.0039 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.0027 | 0.0108 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0049 | 0.0024 | 0.0414 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0066 | 0.0217 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0169 | 0.0192 | 0.0191 |
Brugia malayi | MH1 domain containing protein | 0.0149 | 0.0164 | 0.0547 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0148 | 0.0162 | 0.0298 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0055 | 0.0033 | 0.0028 |
Brugia malayi | Isocitrate dehydrogenase | 0.0047 | 0.0022 | 0.0072 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.0027 | 0.0108 |
Schistosoma mansoni | hypothetical protein | 0.0133 | 0.0142 | 0.0507 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0077 | 0.0064 | 0.0759 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0099 | 0.0094 | 0.0094 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.005 | 0.0027 | 0.0308 |
Loa Loa (eye worm) | hypothetical protein | 0.0412 | 0.0528 | 0.1761 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0058 | 0.0037 | 0.0516 |
Brugia malayi | MH2 domain containing protein | 0.0067 | 0.0049 | 0.0165 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0326 | 0.0409 | 0.0408 |
Schistosoma mansoni | cpg binding protein | 0.0088 | 0.0079 | 0.0284 |
Brugia malayi | Helix-loop-helix DNA-binding domain containing protein | 0.0107 | 0.0106 | 0.0353 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0077 | 0.0064 | 0.2629 |
Onchocerca volvulus | 0.0084 | 0.0073 | 0.0387 | |
Loa Loa (eye worm) | hypothetical protein | 0.0453 | 0.0586 | 0.1954 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0113 | 0.0114 | 0.021 |
Brugia malayi | AMP-binding enzyme family protein | 0.0077 | 0.0064 | 0.0214 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0155 | 0.0172 | 0.0615 |
Entamoeba histolytica | hypothetical protein | 0.0189 | 0.0219 | 1 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0016 | 0.0053 |
Onchocerca volvulus | 0.0054 | 0.0031 | 0.0133 | |
Schistosoma mansoni | hypothetical protein | 0.0189 | 0.0219 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0031 | 0.0102 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0133 | 0.0141 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.1072 | 0.1444 | 0.4816 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0155 | 0.0172 | 0.0615 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0453 | 0.0586 | 0.0586 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0133 | 0.0142 | 0.0141 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0049 | 0.0163 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0169 | 0.0192 | 0.0353 |
Schistosoma mansoni | hypothetical protein | 0.0412 | 0.0528 | 0.1887 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.022 | 0.0262 | 0.3783 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0189 | 0.0219 | 0.0218 |
Brugia malayi | beta-lactamase | 0.0453 | 0.0586 | 0.1955 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0095 | 0.0089 | 0.1519 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0487 | 0.0633 | 0.1168 |
Trichomonas vaginalis | esterase, putative | 0.0453 | 0.0586 | 0.3519 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0189 | 0.0219 | 0.0403 |
Schistosoma mansoni | lamin | 0.0054 | 0.0031 | 0.0111 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0046 | 0.0021 | 0.0213 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0039 | 0.0311 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0058 | 0.0037 | 0.0131 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0133 | 0.0142 | 0.0261 |
Schistosoma mansoni | hypothetical protein | 0.0246 | 0.0298 | 0.1066 |
Trypanosoma brucei | protein kinase, putative | 0.005 | 0.0027 | 0.0455 |
Echinococcus granulosus | tumor protein p63 | 0.3932 | 0.5413 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.022 | 0.0262 | 0.0607 |
Schistosoma mansoni | voltage-gated potassium channel KCNQ | 0.0154 | 0.0171 | 0.061 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0453 | 0.0586 | 0.1427 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0038 | 0.0009 | 0.0009 |
Echinococcus granulosus | GPCR family 2 | 0.0191 | 0.0221 | 0.0408 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0198 | 0.0231 | 0.0529 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0054 | 0.0031 | 0.0102 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0155 | 0.0172 | 0.0615 |
Onchocerca volvulus | 0.0453 | 0.0586 | 0.3517 | |
Trypanosoma brucei | glucosidase, putative | 0.0038 | 0.0009 | 0.0152 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0016 | 0.0015 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0155 | 0.0172 | 0.0172 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0047 | 0.0022 | 0.0368 |
Loa Loa (eye worm) | voltage-gated potassium channel | 0.0137 | 0.0147 | 0.049 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0346 | 0.0437 | 0.7449 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0312 | 0.039 | 0.0719 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0078 | 0.0066 | 0.4368 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.0039 | 0.0038 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.0221 | 0.079 |
Schistosoma mansoni | alpha-glucosidase | 0.0146 | 0.0159 | 0.0568 |
Schistosoma mansoni | lipoxygenase | 0.0328 | 0.0412 | 0.147 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0169 | 0.0192 | 0.0191 |
Brugia malayi | jmjC domain containing protein | 0.0312 | 0.039 | 0.1301 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.0064 | 0.0212 |
Echinococcus multilocularis | potassium voltage gated channel subfamily KQT | 0.0154 | 0.0171 | 0.017 |
Echinococcus granulosus | potassium channel KvQLT family member kqt 1 | 0.0154 | 0.0171 | 0.0315 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0067 | 0.0049 | 0.0049 |
Plasmodium vivax | hypothetical protein, conserved | 0.0453 | 0.0586 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0453 | 0.0586 | 0.3519 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0326 | 0.0409 | 0.0755 |
Loa Loa (eye worm) | hypothetical protein | 0.0532 | 0.0695 | 0.2317 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.0027 | 0.0308 |
Trypanosoma brucei | trypanothione reductase | 0.0087 | 0.0077 | 0.1313 |
Brugia malayi | MH1 domain containing protein | 0.0083 | 0.0071 | 0.0238 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0007 | 0.002 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.0027 | 0.0095 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0095 | 0.0089 | 0.0295 |
Loa Loa (eye worm) | Smad1 | 0.0149 | 0.0164 | 0.0545 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.1207 | 0.1632 | 0.1632 |
Echinococcus granulosus | potassium voltage gated channel subfamily KQT | 0.0063 | 0.0044 | 0.008 |
Schistosoma mansoni | thyroid hormone receptor | 0.0154 | 0.0171 | 0.061 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0198 | 0.0231 | 0.0529 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0453 | 0.0586 | 0.3519 |
Mycobacterium tuberculosis | Probable reductase | 0.0198 | 0.0231 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.0453 | 0.0586 | 0.1954 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0602 | 0.0793 | 0.2644 |
Echinococcus multilocularis | smad | 0.0149 | 0.0164 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.0141 | 0.0468 |
Loa Loa (eye worm) | doublecortin family protein | 0.0078 | 0.0066 | 0.0217 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0142 | 0.0154 | 0.0283 |
Brugia malayi | Cytochrome P450 family protein | 0.0069 | 0.0052 | 0.0174 |
Echinococcus granulosus | geminin | 0.0666 | 0.0881 | 0.1626 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0087 | 0.0077 | 0.1207 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.0221 | 0.079 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0067 | 0.0049 | 0.0163 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0169 | 0.0192 | 0.0638 |
Schistosoma mansoni | hypothetical protein | 0.0191 | 0.0221 | 0.079 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0133 | 0.0141 | 0.2286 |
Brugia malayi | isocitrate dehydrogenase | 0.0047 | 0.0022 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0453 | 0.0586 | 0.1954 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0346 | 0.0437 | 0.741 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0155 | 0.0172 | 0.2939 |
Trypanosoma brucei | cytochrome P450, putative | 0.0046 | 0.0021 | 0.0362 |
Schistosoma mansoni | smad1 5 8 and | 0.0149 | 0.0164 | 0.0586 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0047 | 0.0022 | 0.0077 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0453 | 0.0586 | 0.1955 |
Echinococcus granulosus | cpg binding protein | 0.0088 | 0.0079 | 0.0146 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0142 | 0.0154 | 0.0153 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0113 | 0.0114 | 0.1823 |
Onchocerca volvulus | 0.0078 | 0.0066 | 0.0342 | |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0078 | 0.0066 | 0.012 |
Echinococcus multilocularis | geminin | 0.0666 | 0.0881 | 0.088 |
Schistosoma mansoni | lipoxygenase | 0.0469 | 0.0607 | 0.217 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0099 | 0.0094 | 0.0315 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0054 | 0.0031 | 0.0104 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.0039 | 0.0071 |
Onchocerca volvulus | 0.0453 | 0.0586 | 0.3517 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0059 | 0.0039 | 0.0521 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0049 | 0.0024 | 0.0265 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0189 | 0.0219 | 0.0781 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0113 | 0.0114 | 0.0381 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0038 | 0.0009 | 0.0016 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0038 | 0.0009 | 0.0028 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0038 | 0.0009 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0666 | 0.0881 | 0.3146 |
Onchocerca volvulus | 0.0576 | 0.0755 | 0.455 | |
Echinococcus granulosus | microtubule associated protein 2 | 0.2048 | 0.2799 | 0.517 |
Schistosoma mansoni | microtubule-associated protein tau | 0.2048 | 0.2799 | 1 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0113 | 0.0114 | 0.0642 |
Schistosoma mansoni | smad | 0.0149 | 0.0164 | 0.0586 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0077 | 0.0064 | 0.0759 |
Brugia malayi | Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog | 0.0154 | 0.0171 | 0.057 |
Brugia malayi | hypothetical protein | 0.0133 | 0.0141 | 0.047 |
Brugia malayi | Pre-SET motif family protein | 0.1072 | 0.1444 | 0.4817 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0078 | 0.0066 | 0.0065 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0155 | 0.0172 | 0.0172 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0453 | 0.0586 | 1 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0067 | 0.0049 | 0.0163 |
Schistosoma mansoni | high-affinity choline transporter | 0.0344 | 0.0434 | 0.1549 |
Echinococcus multilocularis | GPCR, family 2 | 0.0191 | 0.0221 | 0.0221 |
Leishmania major | trypanothione reductase | 0.0087 | 0.0077 | 0.1179 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.0172 | 0.0573 |
Schistosoma mansoni | lamin | 0.0054 | 0.0031 | 0.0111 |
Onchocerca volvulus | 0.1219 | 0.1649 | 1 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0453 | 0.0586 | 1 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0047 | 0.0022 | 0.0021 |
Mycobacterium tuberculosis | Conserved protein | 0.0453 | 0.0586 | 0.1427 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0087 | 0.0077 | 0.0255 |
Brugia malayi | beta-lactamase family protein | 0.0453 | 0.0586 | 0.1955 |
Brugia malayi | Bromodomain containing protein | 0.0095 | 0.0089 | 0.0297 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0078 | 0.0066 | 0.0065 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0469 | 0.0607 | 0.0607 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0016 | 0.0042 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0312 | 0.039 | 0.0389 |
Brugia malayi | PHD-finger family protein | 0.0036 | 0.0007 | 0.0022 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0038 | 0.0009 | 0.003 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0077 | 0.0064 | 0.0759 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.003 | 0.0098 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0095 | 0.0089 | 0.1519 |
Brugia malayi | CXXC zinc finger family protein | 0.0084 | 0.0073 | 0.0243 |
Brugia malayi | MH2 domain containing protein | 0.0149 | 0.0164 | 0.0547 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0182 | 0.021 | 0.0475 |
Entamoeba histolytica | hypothetical protein | 0.0189 | 0.0219 | 1 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0016 | 0.0028 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0133 | 0.0141 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0078 | 0.0066 | 0.1009 |
Schistosoma mansoni | intermediate filament proteins | 0.0054 | 0.0031 | 0.0111 |
Schistosoma mansoni | loxhd1 | 0.0078 | 0.0066 | 0.0234 |
Brugia malayi | Cytochrome P450 family protein | 0.0046 | 0.0021 | 0.0071 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0078 | 0.0066 | 0.012 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0453 | 0.0586 | 0.1427 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0602 | 0.0793 | 0.2644 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.2897 | 0.3977 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0039 | 0.0311 |
Schistosoma mansoni | sodium/solute symporter | 0.0038 | 0.0009 | 0.0033 |
Trichomonas vaginalis | set domain proteins, putative | 0.1219 | 0.1649 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.012 | 0.0123 | 0.041 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0453 | 0.0586 | 0.3519 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0049 | 0.0024 | 0.0265 |
Echinococcus granulosus | peregrin | 0.0095 | 0.0089 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0044 | 0.0145 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0453 | 0.0586 | 0.1427 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0105 | 0.0349 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0077 | 0.0064 | 0.0955 |
Schistosoma mansoni | hypothetical protein | 0.1191 | 0.1609 | 0.5749 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0113 | 0.0114 | 0.0408 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0047 | 0.0022 | 0.0251 |
Echinococcus granulosus | transcription factor eb | 0.0107 | 0.0106 | 0.0195 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0047 | 0.0022 | 0.0021 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0344 | 0.0434 | 0.08 |
Echinococcus multilocularis | cpg binding protein | 0.0088 | 0.0079 | 0.0079 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0077 | 0.0064 | 0.0759 |
Echinococcus multilocularis | solute carrier family 5 | 0.0038 | 0.0009 | 0.0009 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0453 | 0.0586 | 1 |
Brugia malayi | PHD-finger family protein | 0.0095 | 0.0089 | 0.0297 |
Plasmodium falciparum | phd finger protein, putative | 0.0095 | 0.0089 | 0.6125 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0169 | 0.0192 | 0.064 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0095 | 0.0089 | 0.0089 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0055 | 0.0033 | 0.0028 |
Plasmodium falciparum | thioredoxin reductase | 0.0087 | 0.0077 | 0.5224 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0149 | 0.0164 | 0.0302 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0047 | 0.0022 | 0.0021 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.0027 | 0.0108 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0453 | 0.0586 | 0.3519 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0191 | 0.0221 | 0.0408 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0113 | 0.0114 | 0.021 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0133 | 0.0141 | 0.2404 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0191 | 0.0221 | 0.0408 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0038 | 0.0009 | 0.0009 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0326 | 0.0409 | 0.0755 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0164 | 0.0184 | 0.3137 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0197 | 0.023 | 0.0765 |
Plasmodium falciparum | glutathione reductase | 0.0087 | 0.0077 | 0.5224 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0198 | 0.0231 | 0.0529 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0055 | 0.0033 | 0.0028 |
Schistosoma mansoni | polycystin 1-related | 0.0078 | 0.0066 | 0.0234 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0487 | 0.0633 | 0.0633 |
Onchocerca volvulus | Huntingtin homolog | 0.0248 | 0.0301 | 0.1779 |
Brugia malayi | Cytochrome P450 family protein | 0.0046 | 0.0021 | 0.0071 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0055 | 0.0033 | 0.0028 |
Echinococcus multilocularis | lamin dm0 | 0.0054 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0009 | 0.003 |
Echinococcus multilocularis | expressed conserved protein | 0.0093 | 0.0086 | 0.0086 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0087 | 0.0078 | 0.0143 |
Brugia malayi | MH1 domain containing protein | 0.0083 | 0.0071 | 0.0238 |
Plasmodium vivax | SET domain protein, putative | 0.0155 | 0.0172 | 0.2853 |
Brugia malayi | hypothetical protein | 0.0078 | 0.0066 | 0.0219 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0164 | 0.0184 | 0.3031 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0453 | 0.0586 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0149 | 0.0164 | 0.0547 |
Echinococcus multilocularis | tumor protein p63 | 0.3932 | 0.5413 | 0.5413 |
Onchocerca volvulus | 0.0155 | 0.0172 | 0.0993 | |
Echinococcus granulosus | intermediate filament protein | 0.0054 | 0.0031 | 0.0057 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0067 | 0.0049 | 0.0165 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0039 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0344 | 0.0434 | 0.1445 |
Brugia malayi | follicle stimulating hormone receptor | 0.0457 | 0.059 | 0.197 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.0184 | 0.0611 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0453 | 0.0586 | 0.1427 |
Mycobacterium tuberculosis | Conserved protein | 0.0453 | 0.0586 | 0.1427 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0087 | 0.0077 | 0.014 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 250 umol/L | Antimycobacterial activity against Mycobacterium tuberculosis CNCTC My 331/88 after 14 days by micromethod | ChEMBL. | 18694614 |
MIC (functional) | = 500 umol/L | Antimycobacterial activity against Mycobacterium tuberculosis CNCTC My 331/88 after 21 days by micromethod | ChEMBL. | 18694614 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.