Detailed information for compound 1180239

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1397.61 | Formula: C63H108N14O21
  • H donors: 18 H acceptors: 21 LogP: -6.3 Rotable bonds: 59
    Rule of 5 violations (Lipinski): 4
  • SMILES: NCCCC[C@@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CC(=O)O)CC(=O)O)[C@H](CC)C)CCCCN)CO)C)NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H]([C@H](O)C)NC(=O)CCCCCCCCC)C
  • InChi: 1S/C63H108N14O21/c1-8-10-11-12-13-14-15-26-46(81)73-51(38(7)80)62(96)77-30-21-25-45(77)58(92)75-50(37(6)79)60(94)66-35(4)52(86)68-39(22-16-18-27-64)53(87)67-36(5)61(95)76-29-20-24-44(76)57(91)72-43(33-78)56(90)69-40(23-17-19-28-65)54(88)74-49(34(3)9-2)59(93)70-41(31-47(82)83)55(89)71-42(63(97)98)32-48(84)85/h34-45,49-51,78-80H,8-33,64-65H2,1-7H3,(H,66,94)(H,67,87)(H,68,86)(H,69,90)(H,70,93)(H,71,89)(H,72,91)(H,73,81)(H,74,88)(H,75,92)(H,82,83)(H,84,85)(H,97,98)/t34-,35-,36-,37+,38+,39-,40-,41-,42-,43-,44-,45-,49-,50-,51-/m0/s1
  • InChiKey: CNBDHUYRSLYFFG-PJSDUUBXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis snurportin 1 0.0325 0.0926 0.0926
Echinococcus granulosus mothers against decapentaplegic 2 0.0054 0.0104 0.016
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0056 0.0111 0.0592
Echinococcus multilocularis ferritin 0.0035 0.0047 0.0047
Trichomonas vaginalis D-aminoacylase, putative 0.0264 0.074 0.2593
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0157
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.006 0.077
Toxoplasma gondii ABC1 family protein 0.0264 0.074 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0173 0.0465 0.1565
Echinococcus granulosus survival motor neuron protein 1 0.0498 0.145 0.2239
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0083 0.0277
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0035 0.0066
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0065 0.0213
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0264 0.074 0.1143
Echinococcus multilocularis expressed protein 0.0035 0.0047 0.0047
Plasmodium vivax hypothetical protein, conserved 0.0119 0.0301 0.3993
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0055 0.0108 0.1427
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0596 0.1747 0.614
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0047 0.0083 0.107
Brugia malayi Associated with TFs and helicases family protein 0.0047 0.0083 0.0157
Echinococcus multilocularis jumonji domain containing protein 0.0165 0.0442 0.0442
Brugia malayi PHD-finger family protein 0.0119 0.0301 0.0568
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0121 0.0306 0.4105
Echinococcus multilocularis L aminoadipate semialdehyde 0.0081 0.0186 0.0186
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0035 0.0066
Schistosoma mansoni TGF-beta signal transducer Smad2 0.012 0.0306 0.0472
Schistosoma mansoni inositol monophosphatase 0.0039 0.006 0.0092
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0101 0.034
Mycobacterium ulcerans hypothetical protein 0.0264 0.074 0.8981
Echinococcus granulosus microtubule associated protein 2 0.2157 0.6476 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0146 0.0382 0.059
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0065 0.0138 0.0138
Brugia malayi MH1 domain containing protein 0.012 0.0306 0.0577
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0065 0.0767
Loa Loa (eye worm) MH1 domain-containing protein 0.012 0.0306 0.0577
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0035 0.0054
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.024 0.0832
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0208 0.0571 0.1115
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0035 0.0066
Echinococcus multilocularis mitogen activated protein kinase 0.0099 0.024 0.024
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0035 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0428 0.1493
Loa Loa (eye worm) thioredoxin reductase 0.0082 0.0189 0.0358
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0065 0.0138 0.1825
Schistosoma mansoni lamin 0.0027 0.0024 0.0037
Loa Loa (eye worm) hypothetical protein 0.0021 0.0004 0.0008
Echinococcus granulosus smad 0.012 0.0306 0.0472
Brugia malayi jmjC domain containing protein 0.0038 0.0057 0.0107
Trypanosoma brucei unspecified product 0.0028 0.0026 0.0241
Echinococcus multilocularis phd:f box containing protein 0.0038 0.0057 0.0057
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0099 0.024 0.3222
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0026 0.0241
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0049 0.0089 0.0138
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0047 0.0083 0.1524
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0596 0.1747 0.614
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0066
Schistosoma mansoni phd/f-box containing protein 0.0038 0.0057 0.0088
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0264 0.074 0.1143
Trichomonas vaginalis penicillin-binding protein, putative 0.0264 0.074 0.2593
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0035 0.0035
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0053 0.0053
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0083 0.1016
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0187 0.0508 0.6127
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0035 0.0054
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0089 0.11
Schistosoma mansoni phosphatidylserine receptor 0.0038 0.0057 0.0088
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0035 0.0066
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0264 0.074 0.145
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0035 0.0066
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0426 0.1232 0.2326
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0035 0.0066
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0033 0.039
Schistosoma mansoni hypothetical protein 0.0147 0.0386 0.0597
Brugia malayi MH2 domain containing protein 0.1768 0.5296 1
Schistosoma mansoni hypothetical protein 0.0325 0.0926 0.143
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0027 0.0324
Schistosoma mansoni cellular tumor antigen P53 0.0153 0.0406 0.0626
Schistosoma mansoni hypothetical protein 0.0691 0.2034 0.3142
Onchocerca volvulus 0.0031 0.0035 0.0039
Plasmodium vivax heterochromatin protein 1, putative 0.0047 0.0083 0.1016
Entamoeba histolytica hypothetical protein 0.0033 0.0041 0.0184
Onchocerca volvulus 0.0958 0.2842 1
Toxoplasma gondii NADPH-glutathione reductase 0.0028 0.0027 0.0307
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0028 0.0027 0.0324
Schistosoma mansoni jumonji domain containing protein 0.0309 0.0877 0.1355
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0187 0.0508 0.0989
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0035 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0083 0.0277
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0596 0.1747 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0187 0.0508 0.0989
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0157
Schistosoma mansoni microtubule-associated protein tau 0.2157 0.6476 1
Loa Loa (eye worm) hypothetical protein 0.0183 0.0497 0.0938
Brugia malayi M-phase phosphoprotein, mpp8 0.0047 0.0083 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0138 0.0469
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0083 0.0277
Leishmania major hypothetical protein, conserved 0.0183 0.0497 0.6697
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0083 0.0277
Brugia malayi Importin beta-1 subunit 0.003 0.0033 0.0062
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0264 0.074 0.145
Echinococcus multilocularis mothers against decapentaplegic 2 0.0054 0.0104 0.0104
Brugia malayi jmjC domain containing protein 0.0038 0.0057 0.0107
Schistosoma mansoni smad 0.0054 0.0104 0.016
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0065 0.0213
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0168 0.0449 0.0693
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.024 0.0832
Entamoeba histolytica hypothetical protein 0.0025 0.0016 0.004
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0028 0.0027 0.0211
Echinococcus multilocularis chromobox protein 1 0.0287 0.081 0.081
Loa Loa (eye worm) hypothetical protein 0.0425 0.1228 0.2319
Trichomonas vaginalis chromobox protein, putative 0.0287 0.081 0.2839
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0249 0.0469
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0041 0.0128
Mycobacterium ulcerans beta-lactamase 0.0264 0.074 0.8981
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0016 0.004
Brugia malayi Bromodomain containing protein 0.0039 0.0059 0.0111
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0009 0.0013
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0049 0.0089 0.1649
Brugia malayi hypothetical protein 0.0126 0.0322 0.0607
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0065 0.0122
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0028 0.0027 0.0324
Giardia lamblia PHD finger protein 15 0.0119 0.0301 0.168
Brugia malayi Inositol-1 0.0039 0.006 0.0113
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0047 0.0083 0.0083
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0071 0.0236
Onchocerca volvulus 0.0081 0.0186 0.0576
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0101 0.034
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0264 0.074 0.8981
Plasmodium falciparum JmjC domain-containing protein, putative 0.0038 0.0057 0.0989
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0057 0.0184
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0056 0.0111 0.1251
Loa Loa (eye worm) hypothetical protein 0.0067 0.0142 0.0269
Echinococcus multilocularis beta LACTamase domain containing family member 0.0264 0.074 0.074
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0082 0.019 0.019
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0057 0.0107
Echinococcus granulosus mothers against decapentaplegic 5 0.012 0.0306 0.0472
Echinococcus multilocularis importin subunit beta 1 0.003 0.0033 0.0033
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0138 0.0359 0.0554
Loa Loa (eye worm) isocitrate dehydrogenase 0.0049 0.0089 0.0168
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0089 0.1168
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0389 0.112 0.112
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0028 0.0027 0.0307
Brugia malayi exodeoxyribonuclease III family protein 0.0056 0.0111 0.021
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0469 0.1362 0.2571
Onchocerca volvulus Alhambra homolog 0.0119 0.0301 0.0982
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0009 0.0016
Mycobacterium tuberculosis Conserved protein 0.0264 0.074 0.145
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0042 0.0527
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0035 0.0066
Trichomonas vaginalis chromobox protein, putative 0.0287 0.081 0.2839
Toxoplasma gondii PHD-finger domain-containing protein 0.0119 0.0301 0.4028
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0024 0.0045
Brugia malayi jmjC domain containing protein 0.0146 0.0382 0.0722
Echinococcus granulosus chromobox protein 1 0.0287 0.081 0.1251
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0197 0.0537 0.0829
Echinococcus multilocularis isocitrate dehydrogenase 0.0049 0.0089 0.0089
Onchocerca volvulus Huntingtin homolog 0.0126 0.0322 0.1057
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0035 0.0066
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0083 0.0428
Trypanosoma cruzi hypothetical protein, conserved 0.0264 0.074 1
Echinococcus multilocularis Chromo domain 0.0047 0.0083 0.0083
Brugia malayi RNA, U transporter 1 0.0087 0.0203 0.0384
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0038 0.0057 0.0731
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0004 0.0008
Echinococcus multilocularis zinc finger protein 0.002 0.0001 0.0001
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0047 0.0083 0.0157
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0389 0.112 0.1729
Brugia malayi MH1 domain containing protein 0.0067 0.0142 0.0269
Brugia malayi MAP kinase sur-1 0.0099 0.024 0.0454
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0291 0.0823 1
Echinococcus granulosus ferritin 0.0035 0.0047 0.0072
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0055 0.0108 0.1361
Echinococcus granulosus dna polymerase eta 0.0041 0.0065 0.01
Giardia lamblia Kinase, CMGC MAPK 0.0099 0.024 0.1334
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0083 0.0277
Loa Loa (eye worm) hypothetical protein 0.0264 0.074 0.1397
Brugia malayi SET domain containing protein 0.0051 0.0096 0.0182
Echinococcus multilocularis lysine specific demethylase 5A 0.0144 0.0376 0.0376
Brugia malayi intermediate filament protein 0.0027 0.0024 0.0045
Loa Loa (eye worm) jmjC domain-containing protein 0.0245 0.0684 0.1292
Leishmania major hypothetical protein, conserved 0.0038 0.0057 0.0731
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0038 0.0057 0.0731
Echinococcus granulosus geminin 0.0691 0.2034 0.3142
Mycobacterium tuberculosis Probable hydrolase 0.0264 0.074 0.145
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0083 0.0277
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0056 0.0111 0.0202
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0083 0.0277
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0099 0.024 0.3222
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0187 0.0508 0.0989
Schistosoma mansoni hypothetical protein 0.0197 0.0537 0.0829
Echinococcus multilocularis tar DNA binding protein 0.0469 0.1362 0.1362
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0051 0.0079
Echinococcus multilocularis muscleblind protein 0.0145 0.038 0.038
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1686 0.5048 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0089 0.0089
Echinococcus granulosus jumonji domain containing 1A 0.0038 0.0057 0.0088
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0028 0.0027 0.0324
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0057 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0286 0.0992
Leishmania major DNA polymerase eta, putative 0.0041 0.0065 0.0838
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0325 0.0926 0.1749
Loa Loa (eye worm) hypothetical protein 0.0041 0.0065 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0161 0.0428 0.1493
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0138 0.0359 0.0554
Trichomonas vaginalis mercuric reductase, putative 0.0028 0.0027 0.008
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0039 0.0058 0.1019
Loa Loa (eye worm) MH2 domain-containing protein 0.0054 0.0104 0.0196
Echinococcus multilocularis GPCR, family 2 0.0197 0.0537 0.0537
Schistosoma mansoni ran 0.0022 0.0009 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0065 0.0767
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0138 0.0469
Echinococcus granulosus JmjC domain containing protein 4 0.0038 0.0057 0.0088
Brugia malayi Heterochromatin protein 1 0.0287 0.081 0.153
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0016 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0083 0.0277
Loa Loa (eye worm) hypothetical protein 0.0145 0.038 0.0718
Plasmodium falciparum thioredoxin reductase 0.0028 0.0027 0.0374
Echinococcus granulosus tar DNA binding protein 0.0469 0.1362 0.2103
Trichomonas vaginalis D-aminoacylase, putative 0.0264 0.074 0.2593
Echinococcus granulosus PHD finger protein rhinoceros 0.0119 0.0301 0.0464
Loa Loa (eye worm) hypothetical protein 0.0126 0.0323 0.0609
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.004 0.0063 0.0063
Schistosoma mansoni apoferritin-2 0.0035 0.0047 0.0072
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0033 0.0042 0.0065
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0028 0.0027 0.0249
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0596 0.1747 0.614
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0041 0.0077
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0065 0.0138 0.0741
Leishmania major DNA polymerase kappa, putative 0.0041 0.0065 0.0838
Brugia malayi latrophilin 2 splice variant baaae 0.0425 0.1228 0.2319
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0024 0.0045
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0047 0.0075
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0065 0.0323
Echinococcus multilocularis muscleblind protein 1 0.0145 0.038 0.038
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0035 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0083 0.0277
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0056 0.0111 0.021
Brugia malayi Smad1 0.012 0.0306 0.0577
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0197 0.0537 0.0829
Mycobacterium tuberculosis Probable lipase LipE 0.0264 0.074 0.145
Entamoeba histolytica hypothetical protein 0.0147 0.0386 0.2173
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0071 0.0236
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0128 0.168
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0042 0.0132
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0083 0.0277
Schistosoma mansoni hypothetical protein 0.0082 0.019 0.0293
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0157
Schistosoma mansoni chromobox protein 0.0287 0.081 0.1251
Echinococcus granulosus snurportin 1 0.0325 0.0926 0.143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0071 0.0236
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0065 0.0138 0.1825
Echinococcus multilocularis survival motor neuron protein 1 0.0498 0.145 0.145
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0047 0.0083 0.0128
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0128 0.1453
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0056 0.0111 0.0172
Leishmania major trypanothione reductase 0.0082 0.0189 0.2528
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0108 0.0366
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.0138 0.0469
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0009 0.0076
Mycobacterium ulcerans esterase/lipase LipP 0.0264 0.074 0.8981
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0065 0.0838
Schistosoma mansoni coup transcription factor 0.0031 0.0035 0.0054
Schistosoma mansoni importin beta-1 0.003 0.0033 0.0051
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0083 0.0277
Schistosoma mansoni jumonji domain containing protein 0.0038 0.0057 0.0088
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0047 0.0083 0.107
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0081 0.0186 0.0351
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0033 0.0333
Echinococcus granulosus jumonji domain containing protein 0.0165 0.0442 0.0682
Schistosoma mansoni tar DNA-binding protein 0.0469 0.1362 0.2103
Schistosoma mansoni zinc finger protein 0.002 0.0001 0.0002
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0039 0.0058 0.068
Brugia malayi Bromodomain containing protein 0.0121 0.0308 0.0582
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0065 0.0838
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0061 0.0125 0.0125
Schistosoma mansoni DNA polymerase eta 0.0041 0.0065 0.01
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0065 0.0109
Plasmodium falciparum phd finger protein, putative 0.0119 0.0301 0.5984
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0035 0.0054
Loa Loa (eye worm) PHD-finger family protein 0.0119 0.0301 0.0568
Schistosoma mansoni lamin 0.0027 0.0024 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0057 0.0184
Schistosoma mansoni smad 0.012 0.0306 0.0472
Echinococcus multilocularis chromobox protein 1 0.0287 0.081 0.081
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0053 0.0082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0101 0.034
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0035 0.0054
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0082 0.019 0.0293
Brugia malayi nuclear hormone receptor 0.0031 0.0035 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0042 0.0132
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0128 0.0197
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0047 0.0462
Treponema pallidum NADH oxidase 0.0028 0.0027 0.0099
Loa Loa (eye worm) nuclear factor I 0.0067 0.0142 0.0269
Echinococcus multilocularis smad 0.012 0.0306 0.0306
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.001 0.0091
Echinococcus granulosus expressed protein 0.0364 0.1042 0.161
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0038 0.0057 0.066
Brugia malayi MH2 domain containing protein 0.012 0.0306 0.0577
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0197 0.0537 0.0537
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0049 0.0089 0.0158
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.006 0.0754
Mycobacterium leprae conserved hypothetical protein 0.0264 0.074 0.8981
Echinococcus granulosus expressed protein 0.0035 0.0047 0.0072
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0028 0.0027 0.0027
Echinococcus multilocularis chromobox protein 2 0.0047 0.0083 0.0083
Plasmodium falciparum ataxin-2 like protein, putative 0.0183 0.0497 1
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0035 0.0066
Echinococcus multilocularis geminin 0.0691 0.2034 0.2034
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0038 0.0057 0.0715
Brugia malayi RNA binding protein 0.0469 0.1362 0.2571
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0065 0.0767
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0101 0.034
Brugia malayi Latrophilin receptor protein 2 0.0197 0.0537 0.1013
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0051 0.0051
Entamoeba histolytica hypothetical protein 0.0047 0.0083 0.0428
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0035 0.0039
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.001 0.001
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0049 0.0089 0.0137
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0128 0.0235
Echinococcus granulosus muscleblind protein 0.0145 0.038 0.0587
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0841 0.249 0.4702
Loa Loa (eye worm) hypothetical protein 0.0622 0.1824 0.3444
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0065 0.0767
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0147 0.0386 0.0597
Trypanosoma brucei protein kinase, putative 0.0099 0.024 0.317
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0035 0.0066
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0026 0.0019 0.0141
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.024 0.0832
Entamoeba histolytica hypothetical protein 0.0047 0.0083 0.0428
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0035 0.0066
Mycobacterium ulcerans bacterioferritin BfrA 0.0035 0.0047 0.0453
Trichomonas vaginalis Heterochromatin protein, putative 0.0047 0.0083 0.0277
Loa Loa (eye worm) jmjC domain-containing protein 0.0146 0.0382 0.0722
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0053 0.0082
Trichomonas vaginalis set domain proteins, putative 0.0958 0.2842 1
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0101 0.034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0108 0.0366
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0035 0.0066
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0028 0.0027 0.0324
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0056 0.0111 0.1406
Brugia malayi N-terminal motif family protein 0.0374 0.1073 0.2026
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0028 0.0027 0.1686
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0065 0.0109
Trypanosoma brucei PAB1-binding protein , putative 0.0183 0.0497 0.6672
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0426 0.1232 0.1902
Schistosoma mansoni z-protein (S1r protein) 0.0037 0.0053 0.0082
Echinococcus granulosus importin subunit beta 1 0.003 0.0033 0.0051
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0047 0.0083 0.107
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0099 0.024 0.3222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0079 0.0262
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0291 0.0823 0.1614
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0071 0.0236
Trichomonas vaginalis penicillin-binding protein, putative 0.0264 0.074 0.2593
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0035 0.0054
Loa Loa (eye worm) heterochromatin protein 1 0.0287 0.081 0.153
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0033 0.0042 0.0065
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0089 0.0089
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0099 0.024 0.3222
Mycobacterium tuberculosis Probable lipase LipD 0.0264 0.074 0.145
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0033 0.0042 0.0527
Loa Loa (eye worm) hypothetical protein 0.0126 0.0322 0.0607
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0058 0.068
Onchocerca volvulus 0.0264 0.074 0.2541
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0065 0.01
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0138 0.0359 0.0359
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0057 0.0107
Loa Loa (eye worm) beta-lactamase 0.0264 0.074 0.1397
Echinococcus granulosus chromobox protein 1 0.0287 0.081 0.1251
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0128 0.0197
Schistosoma mansoni ferritin 0.0035 0.0047 0.0072
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0111 0.1406
Schistosoma mansoni hypothetical protein 0.0691 0.2034 0.3142
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0027 0.0324
Trichomonas vaginalis ferritin, putative 0.0035 0.0047 0.0149
Loa Loa (eye worm) hypothetical protein 0.0041 0.0066 0.0125
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0028 0.0027 0.0249
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0028 0.0027 0.0042
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0374 0.1073 0.3722
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0056 0.0111 0.2107
Schistosoma mansoni tar DNA-binding protein 0.0469 0.1362 0.2103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0083 0.0277
Loa Loa (eye worm) hypothetical protein 0.0145 0.038 0.0718
Echinococcus granulosus beta LACTamase domain containing family member 0.0264 0.074 0.1143
Echinococcus multilocularis microtubule associated protein 2 0.2157 0.6476 0.6476
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0035 0.0035
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0049 0.0089 0.1168
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0049 0.0089 0.0089
Trypanosoma cruzi DNA polymerase eta, putative 0.0041 0.0065 0.0838
Echinococcus multilocularis mothers against decapentaplegic 6 0.0054 0.0104 0.0104
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.006 0.077
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0065 0.0767
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0111 0.0378
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0083 0.0277
Echinococcus multilocularis thioredoxin glutathione reductase 0.0083 0.0191 0.0191
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0049 0.0089 0.0089
Echinococcus multilocularis expressed protein 0.0364 0.1042 0.1042
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0026 0.0241
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0028 0.0027 0.0374
Schistosoma mansoni jumonji/arid domain-containing protein 0.0146 0.0382 0.059
Trypanosoma brucei DNA polymerase eta, putative 0.0041 0.0065 0.0767
Loa Loa (eye worm) hypothetical protein 0.0264 0.074 0.1397
Echinococcus multilocularis serine protein kinase ATM 0.0033 0.0041 0.0041
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0596 0.1747 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0033 0.0042 0.0079
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0028 0.0027 0.0051
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0028 0.0027 0.0034
Trypanosoma brucei trypanothione reductase 0.0082 0.0189 0.2471
Loa Loa (eye worm) hypothetical protein 0.0039 0.0059 0.0111
Toxoplasma gondii target of rapamycin (TOR), putative 0.0053 0.0101 0.1309
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0035 0.0047 0.0453
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0035 0.0035
Echinococcus multilocularis dna polymerase eta 0.0041 0.0065 0.0065
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0028 0.0027 0.0211
Brugia malayi Pre-SET motif family protein 0.0121 0.0306 0.0578
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0101 0.034
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0028 0.0027 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0071 0.0236
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0065 0.0838
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0035 0.0066
Brugia malayi MH2 domain containing protein 0.0054 0.0104 0.0196
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.001 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0035 0.0066
Loa Loa (eye worm) hypothetical protein 0.0027 0.0022 0.0042
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0128 0.0128
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0066
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0065 0.0122
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0033 0.0042 0.0042
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0035 0.0054
Brugia malayi jmjC domain containing protein 0.0389 0.112 0.2114
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0099 0.024 0.3222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0042 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0064 0.021
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0047 0.0083 0.0128
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0016 0.017
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0082 0.0189 0.0357
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0071 0.0236
Trypanosoma cruzi PAB1-binding protein , putative 0.0183 0.0497 0.6697
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0028 0.0027 0.0324
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0083 0.0277
Entamoeba histolytica hypothetical protein 0.0047 0.0083 0.0428
Loa Loa (eye worm) hypothetical protein 0.0119 0.0301 0.0568
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0028 0.0027 0.0211
Brugia malayi nuclear receptor NHR-88 0.0031 0.0035 0.0066
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0035 0.0066
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0161 0.0428 0.1434
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0157
Brugia malayi Valyl-tRNA synthetase 0.0047 0.0083 0.0157
Loa Loa (eye worm) glutathione reductase 0.0082 0.0189 0.0358
Brugia malayi jmjC domain containing protein 0.0038 0.0057 0.0107
Brugia malayi Calcitonin receptor-like protein seb-1 0.0622 0.1824 0.3444
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0033 0.0041 0.0063
Schistosoma mansoni ap endonuclease 0.0056 0.0111 0.0172
Echinococcus multilocularis Smad4 0.012 0.0306 0.0306
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0035 0.0066
Brugia malayi PHD-finger family protein 0.0041 0.0064 0.0121
Plasmodium falciparum importin beta, putative 0.003 0.0033 0.0499
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0027 0.0021 0.0246
Echinococcus multilocularis Chromobox protein 3 0.0047 0.0083 0.0083
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0024 0.0045
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0157
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0047 0.0083 0.1524
Trypanosoma brucei hypothetical protein, conserved 0.0264 0.074 1
Mycobacterium tuberculosis Probable esterase LipL 0.0264 0.074 0.145
Trichomonas vaginalis glutathione reductase, putative 0.0028 0.0027 0.008
Echinococcus granulosus mitogen activated protein kinase 0.0099 0.024 0.0371
Loa Loa (eye worm) hypothetical protein 0.0138 0.0359 0.0678
Brugia malayi steroid hormone receptor 0.0031 0.0035 0.0066
Schistosoma mansoni hypothetical protein 0.0021 0.0004 0.0007
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0622 0.1824 0.3444
Schistosoma mansoni transcription factor LCR-F1 0.0147 0.0386 0.0597
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0038 0.0057 0.0715
Schistosoma mansoni apoferritin-2 0.0035 0.0047 0.0072
Loa Loa (eye worm) helicase 0.0047 0.0083 0.0157
Trichomonas vaginalis PIKK family atypical protein kinase 0.005 0.0093 0.0314
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0083 0.0277
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.006 0.0195
Schistosoma mansoni Smad4 0.0054 0.0104 0.016
Loa Loa (eye worm) hypothetical protein 0.0264 0.074 0.1397
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0065 0.0838
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0047 0.0083 0.0128
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0035 0.0054
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0035 0.0039
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0065 0.0122
Trypanosoma brucei DNA polymerase kappa, putative 0.0028 0.0026 0.0241
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0119 0.0301 0.0464
Schistosoma mansoni hypothetical protein 0.0197 0.0537 0.0829
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0099 0.024 0.317
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0049 0.0089 0.0089
Onchocerca volvulus 0.0047 0.0083 0.021
Loa Loa (eye worm) hypothetical protein 0.0038 0.0057 0.0107
Brugia malayi Bromodomain containing protein 0.0076 0.0172 0.0325
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0035 0.0054
Mycobacterium tuberculosis Conserved protein 0.0264 0.074 0.145
Brugia malayi beta-lactamase family protein 0.0264 0.074 0.1397
Echinococcus granulosus lysine specific demethylase 5A 0.0146 0.0382 0.059
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0035 0.0054
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0208 0.0571 0.6905
Echinococcus multilocularis peregrin 0.0121 0.0308 0.0308
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0027 0.0324
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0054 0.0104 0.0284
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0009 0.0016
Plasmodium vivax thioredoxin reductase, putative 0.0082 0.0189 0.2471
Loa Loa (eye worm) inositol-1 0.0039 0.006 0.0113
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0081 0.0186 0.0287
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.006 0.077
Echinococcus granulosus lysine specific demethylase 6a 0.0038 0.0057 0.0088
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0596 0.1747 0.614
Entamoeba histolytica hypothetical protein 0.0147 0.0386 0.2173
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0035 0.0066
Schistosoma mansoni Smad4 0.0054 0.0104 0.016
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0066
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0049 0.0089 0.11
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0121 0.0306 0.0473
Loa Loa (eye worm) hypothetical protein 0.0264 0.074 0.1397
Treponema pallidum exodeoxyribonuclease (exoA) 0.0056 0.0111 0.0586
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0035 0.0066
Loa Loa (eye worm) hypothetical protein 0.0374 0.1073 0.2026
Trichomonas vaginalis chromobox protein, putative 0.0173 0.0465 0.1623
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0083 0.0277
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0083 0.0277
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0033 0.0042 0.0527
Onchocerca volvulus 0.0168 0.0449 0.1507
Plasmodium falciparum ataxin-2 like protein, putative 0.0183 0.0497 1
Onchocerca volvulus 0.0153 0.0406 0.1354
Schistosoma mansoni ferritin 0.0035 0.0047 0.0072
Trichomonas vaginalis D-aminoacylase, putative 0.0264 0.074 0.2593
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.004 0.0063 0.0097
Leishmania major hypothetical protein, conserved 0.0264 0.074 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0035 0.0066
Brugia malayi Thioredoxin reductase 0.0082 0.0189 0.0358
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0596 0.1747 0.614
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0065 0.0138 0.0741
Trichomonas vaginalis CMGC family protein kinase 0.0099 0.024 0.0832
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0128 0.0197
Echinococcus granulosus mitogen activated protein kinase 3 0.0099 0.024 0.0371
Schistosoma mansoni chromobox protein 0.0287 0.081 0.1251
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0065 0.0138 0.026
Schistosoma mansoni smad1 5 8 and 0.012 0.0306 0.0472
Mycobacterium tuberculosis Conserved protein 0.0264 0.074 0.145
Trichomonas vaginalis esterase, putative 0.0264 0.074 0.2593
Treponema pallidum fructose-bisphosphate aldolase 0.0596 0.1747 1
Loa Loa (eye worm) hypothetical protein 0.0498 0.145 0.2738
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0043 0.0072 0.0111
Schistosoma mansoni protein phosphatase 2C 0.0038 0.0057 0.0088
Schistosoma mansoni ferritin 0.0035 0.0047 0.0072
Schistosoma mansoni tar DNA-binding protein 0.0469 0.1362 0.2103
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0033 0.0041 0.0437
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0083 0.0277
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0035 0.0054
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0099 0.024 0.3222
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0596 0.1747 0.614
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0035 0.0054
Loa Loa (eye worm) MH1 domain-containing protein 0.0054 0.0104 0.0196
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0056 0.0111 0.0111
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0065 0.0838
Loa Loa (eye worm) transcription factor SMAD2 0.1768 0.5296 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0035 0.0054
Plasmodium vivax JmjC domain containing protein 0.0038 0.0057 0.066
Toxoplasma gondii PHD-finger domain-containing protein 0.0039 0.0058 0.0735
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0083 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0083 0.0277
Echinococcus granulosus TGF beta signal transducer SmadC 0.012 0.0306 0.0472
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0066
Echinococcus multilocularis lamin dm0 0.0027 0.0024 0.0024
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0049 0.0089 0.0137
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0264 0.074 0.1397
Schistosoma mansoni ferritin 0.0035 0.0047 0.0072
Schistosoma mansoni chromobox protein 0.0047 0.0083 0.0128
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0065 0.0138 0.0212
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.0089 0.1153
Brugia malayi hypothetical protein 0.0498 0.145 0.2738
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0056 0.0111 0.1471
Schistosoma mansoni smad1 5 8 and 0.012 0.0306 0.0472
Schistosoma mansoni tar DNA-binding protein 0.0469 0.1362 0.2103
Mycobacterium tuberculosis Probable oxidoreductase 0.0208 0.0571 0.1115
Brugia malayi hypothetical protein 0.0183 0.0497 0.0938
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0035 0.0035
Trichomonas vaginalis hypothetical protein 0.0047 0.0083 0.0277
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0083 0.0277
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0119 0.0301 0.0464
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0028 0.0027 0.0249
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0035 0.0047 0.3623
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0108 0.0366
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0187 0.0508 0.0989
Treponema pallidum bacterioferrin (TpF1) 0.0035 0.0047 0.0212
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0157
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0035 0.0066
Echinococcus granulosus Chromobox protein 3 0.0047 0.0083 0.0128
Brugia malayi regulator of G-protein signaling egl-10 0.0037 0.0053 0.01
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0197 0.0537 0.0537
Trichomonas vaginalis chromobox protein, putative 0.0173 0.0465 0.1623
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0071 0.0236
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0065 0.0767
Trypanosoma cruzi PAB1-binding protein , putative 0.0183 0.0497 0.6697
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0196
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0065 0.0767
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0038 0.0057 0.0088
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0027 0.0324
Leishmania major phosphatidylinositol 3-kinase, putative 0.0033 0.0042 0.0527
Mycobacterium ulcerans bacterioferritin BfrB 0.0035 0.0047 0.0453
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0035 0.0054
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0057 0.0107
Brugia malayi chromobox protein homolog 3 0.0161 0.0428 0.0808
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0027 0.0324
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0056 0.0111 0.0592
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0306 0.0577
Schistosoma mansoni hypothetical protein 0.0197 0.0537 0.0829
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0009 0.0076
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0065 0.0138 0.1825
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0065 0.0677
Echinococcus granulosus mothers against decapentaplegic 6 0.0054 0.0104 0.016
Loa Loa (eye worm) hypothetical protein 0.0047 0.0083 0.0157
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.001 0.0016
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0622 0.1824 0.3444
Onchocerca volvulus 0.0047 0.0083 0.021
Echinococcus granulosus chromobox protein 2 0.0047 0.0083 0.0128
Loa Loa (eye worm) hypothetical protein 0.0041 0.0064 0.0121
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0426 0.1232 0.1902
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0083 0.0277
Echinococcus multilocularis tumor protein p63 0.1048 0.3117 0.3117
Toxoplasma gondii FATC domain-containing protein 0.0033 0.0041 0.0494
Brugia malayi Isocitrate dehydrogenase 0.0049 0.0089 0.0168
Schistosoma mansoni hypothetical protein 0.0425 0.1228 0.1896
Echinococcus granulosus Chromo domain 0.0047 0.0083 0.0128
Brugia malayi mothers against decapentaplegic homolog 3 0.0054 0.0104 0.0196
Brugia malayi MH1 domain containing protein 0.012 0.0306 0.0577
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0035 0.0035
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0035 0.0066
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0035 0.0054
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0021 0.0004 0.0008
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.001 0.0074
Giardia lamblia GTOR 0.0065 0.0138 0.0741
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.006 0.4918
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.006 0.0195
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0056 0.0111 0.1471
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0035 0.0039
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0426 0.1232 0.2326
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0033 0.0042 0.0454
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0128 0.1453
Schistosoma mansoni hypothetical protein 0.0102 0.0249 0.0384
Toxoplasma gondii LsmAD domain-containing protein 0.0183 0.0497 0.6692
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.007 0.0233
Loa Loa (eye worm) hypothetical protein 0.0043 0.0072 0.0136
Echinococcus multilocularis JmjC domain containing protein 4 0.0038 0.0057 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0264 0.074 1
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0047 0.0083 0.0428
Loa Loa (eye worm) hypothetical protein 0.0264 0.074 0.1397
Leishmania major GTP-binding protein, putative 0.0022 0.0009 0.0076
Schistosoma mansoni ferritin light chain 0.0035 0.0047 0.0072
Echinococcus multilocularis TGF beta signal transducer SmadC 0.012 0.0306 0.0306
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0108 0.0366
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0061 0.0125 0.0193
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.006 0.0092
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0033 0.0333
Echinococcus granulosus L aminoadipate semialdehyde 0.0081 0.0186 0.0287
Echinococcus granulosus lamin 0.0027 0.0024 0.0037
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0016 0.004
Entamoeba histolytica hypothetical protein 0.0023 0.001 0.0006
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0065 0.0138 0.0212
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0053 0.0053
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0035 0.0054
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0099 0.024 0.321
Schistosoma mansoni Smad4 0.012 0.0306 0.0472
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.001 0.0074
Onchocerca volvulus 0.0264 0.074 0.2541
Plasmodium vivax glutathione reductase, putative 0.0082 0.0189 0.2471
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0066
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0035 0.0054
Schistosoma mansoni intermediate filament proteins 0.0027 0.0024 0.0037
Echinococcus multilocularis mothers against decapentaplegic 5 0.012 0.0306 0.0306
Giardia lamblia NADH oxidase lateral transfer candidate 0.0028 0.0027 0.0105
Mycobacterium ulcerans lipase LipD 0.0264 0.074 0.8981
Brugia malayi beta-lactamase 0.0264 0.074 0.1397
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0049 0.0089 0.11
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.006 0.0294
Plasmodium vivax SET domain protein, putative 0.0121 0.0306 0.407
Brugia malayi RNA recognition motif domain containing protein 0.0469 0.1362 0.2571
Trichomonas vaginalis conserved hypothetical protein 0.0114 0.0286 0.0992
Echinococcus granulosus intermediate filament protein 0.0027 0.0024 0.0037
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0065 0.0767
Brugia malayi AF-10 protein 0.0039 0.0058 0.011
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.006 0.0615
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0035 0.0066
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0035 0.0054
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0035 0.0054
Mycobacterium tuberculosis Probable reductase 0.0187 0.0508 0.0989
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.006 0.0699
Loa Loa (eye worm) hypothetical protein 0.0081 0.0186 0.0351
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0596 0.1747 0.614
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0028 0.0027 0.0324
Echinococcus granulosus lamin dm0 0.0027 0.0024 0.0037
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0039 0.0058 0.068
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0147 0.0386 0.0386
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0028 0.0027 0.0374
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0028 0.0027 0.0324
Entamoeba histolytica hypothetical protein 0.0147 0.0386 0.2173
Echinococcus multilocularis lysine specific demethylase 6a 0.0038 0.0057 0.0057
Brugia malayi hypothetical protein 0.0118 0.03 0.0566
Plasmodium vivax ataxin-2 like protein, putative 0.0183 0.0497 0.6672
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0083 0.0277
Loa Loa (eye worm) phosphatidylinositol 3 0.0065 0.0138 0.026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0042 0.0132
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0426 0.1232 0.1902
Onchocerca volvulus Huntingtin homolog 0.0126 0.0322 0.1057
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0065 0.0065
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0065 0.01
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0128 0.1453
Loa Loa (eye worm) hypothetical protein 0.0037 0.0053 0.01
Loa Loa (eye worm) hypothetical protein 0.0197 0.0537 0.1013
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0065 0.0767
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0128 0.1694
Mycobacterium leprae Probable lipase LipE 0.0264 0.074 0.8981
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0049 0.0089 0.1168
Entamoeba histolytica hypothetical protein 0.0147 0.0386 0.2173
Giardia lamblia Fructose-bisphosphate aldolase 0.0596 0.1747 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.001 0.0015
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0035 0.0054
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0037 0.0053 0.01
Echinococcus granulosus thioredoxin glutathione reductase 0.0083 0.0191 0.0295
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0056 0.0111 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0426 0.1232 0.1902
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0035 0.0035
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0033 0.0042 0.0079
Echinococcus multilocularis jumonji domain containing 1A 0.0038 0.0057 0.0057
Echinococcus multilocularis mitogen activated protein kinase 3 0.0099 0.024 0.024
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0065 0.0767
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.024 0.0371
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0065 0.0767
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.006 0.006
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0033 0.0041 0.051
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0065 0.0767
Loa Loa (eye worm) hypothetical protein 0.0264 0.074 0.1397
Trypanosoma brucei unspecified product 0.0028 0.0026 0.0241
Echinococcus granulosus zinc finger protein 0.002 0.0001 0.0002
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0047 0.0083 0.0128
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0039 0.0058 0.0735
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0021 0.0004 0.0008
Brugia malayi ecdysteroid receptor 0.0031 0.0035 0.0066
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0426 0.1232 0.1902
Echinococcus multilocularis PHD finger protein rhinoceros 0.0119 0.0301 0.0301
Loa Loa (eye worm) hypothetical protein 0.0126 0.0322 0.0607
Echinococcus multilocularis musashi 0.0027 0.0024 0.0024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0055 0.0108 0.0366
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0065 0.0767
Trypanosoma cruzi trypanothione reductase, putative 0.0082 0.0189 0.2528
Schistosoma mansoni hypothetical protein 0.0047 0.0083 0.0128
Mycobacterium tuberculosis Probable dehydrogenase 0.0187 0.0508 0.0989
Brugia malayi jmjC domain containing protein 0.0038 0.0057 0.0107
Loa Loa (eye worm) TAR-binding protein 0.0469 0.1362 0.2571
Brugia malayi hypothetical protein 0.0147 0.0386 0.0729
Loa Loa (eye worm) MH2 domain-containing protein 0.1768 0.5296 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0197 0.0537 0.1013
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0028 0.0027 0.0249
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0035 0.0066
Toxoplasma gondii isocitrate dehydrogenase 0.0049 0.0089 0.1153
Brugia malayi glutathione reductase 0.0082 0.0189 0.0358
Loa Loa (eye worm) hypothetical protein 0.0161 0.0428 0.0808
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0083 0.0277
Plasmodium vivax importin-beta 2, putative 0.003 0.0033 0.0333
Plasmodium falciparum glutathione reductase 0.0082 0.0189 0.3703
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0079 0.0262
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0065 0.0138 0.1762
Echinococcus granulosus GPCR family 2 0.0197 0.0537 0.0829
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0197 0.0537 0.0829
Schistosoma mansoni bromodomain containing protein 0.0064 0.0136 0.021
Echinococcus granulosus dna polymerase kappa 0.0041 0.0065 0.01
Echinococcus granulosus tumor protein p63 0.1048 0.3117 0.4813
Brugia malayi beta-lactamase family protein 0.0264 0.074 0.1397
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0053 0.0082
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0045
Loa Loa (eye worm) RNA binding protein 0.0469 0.1362 0.2571
Schistosoma mansoni ferritin light chain 0.0035 0.0047 0.0072
Brugia malayi PHD-finger family protein 0.0025 0.0018 0.0033
Onchocerca volvulus 0.0102 0.0249 0.0797
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0116 0.0293 0.0452
Schistosoma mansoni ran 0.0022 0.0009 0.0013
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0121 0.0306 0.0306
Schistosoma mansoni smad1 5 8 and 0.012 0.0306 0.0472
Trichomonas vaginalis ap endonuclease, putative 0.0056 0.0111 0.0378
Schistosoma mansoni tar DNA-binding protein 0.0469 0.1362 0.2103
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0028 0.0027 0.1686
Echinococcus granulosus peregrin 0.0121 0.0308 0.0476
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0291 0.0823 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0264 0.074 0.145
Loa Loa (eye worm) CHromoDomain protein family member 0.0049 0.0089 0.0168
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0426 0.1232 0.1232
Plasmodium falciparum heterochromatin protein 1 0.0047 0.0083 0.1524
Brugia malayi F/Y-rich N-terminus family protein 0.0045 0.0078 0.0147
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0028 0.0027 0.0042
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0065 0.0677
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0033 0.0042 0.0454
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0009 0.0059
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0049 0.0089 0.0138
Schistosoma mansoni ap endonuclease 0.0056 0.0111 0.0172
Schistosoma mansoni hypothetical protein 0.0039 0.0058 0.009
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0009 0.0009
Trichomonas vaginalis ran, putative 0.0022 0.0009 0.0015
Brugia malayi CHD4 protein 0.0049 0.0089 0.0168
Brugia malayi MH2 domain containing protein 0.012 0.0306 0.0577
Onchocerca volvulus 0.0264 0.074 0.2541
Loa Loa (eye worm) hypothetical protein 0.0072 0.0159 0.03
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0028 0.0027 0.0249
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0208 0.0571 0.1115
Echinococcus granulosus phd:f box containing protein 0.0038 0.0057 0.0088
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0062
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0056 0.0111 0.1471
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0065 0.01
Toxoplasma gondii thioredoxin reductase 0.0082 0.0189 0.2515
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0031 0.0034 0.0343
Leishmania major importin beta-1 subunit, putative 0.0025 0.0016 0.017
Loa Loa (eye worm) Smad1 0.012 0.0306 0.0577
Loa Loa (eye worm) hypothetical protein 0.0031 0.0035 0.0066
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.001 0.0016
Trypanosoma cruzi trypanothione reductase, putative 0.0028 0.0027 0.0324
Loa Loa (eye worm) hypothetical protein 0.0204 0.0558 0.1053
Brugia malayi Muscleblind-like protein 0.0145 0.038 0.0718
Brugia malayi hypothetical protein 0.0047 0.0083 0.0157
Loa Loa (eye worm) hypothetical protein 0.0153 0.0406 0.0766
Echinococcus granulosus serine protein kinase ATM 0.0033 0.0041 0.0063
Trypanosoma brucei unspecified product 0.0041 0.0065 0.0767
Trichomonas vaginalis PIKK family atypical protein kinase 0.0053 0.0101 0.034
Schistosoma mansoni inositol monophosphatase 0.0039 0.006 0.0092
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0028 0.0027 0.0249
Loa Loa (eye worm) hypothetical protein 0.0027 0.0021 0.004
Onchocerca volvulus 0.0126 0.0323 0.1061
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0426 0.1232 0.1232
Toxoplasma gondii exonuclease III APE 0.0056 0.0111 0.1456
Brugia malayi Protein cec-1. 0.0047 0.0083 0.0157
Plasmodium falciparum thioredoxin reductase 0.0082 0.0189 0.3703
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0035 0.0035
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.006 0.0195
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.001 0.0015
Brugia malayi MH1 domain containing protein 0.0067 0.0142 0.0269
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0035 0.0047 0.0073
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0042 0.0132
Brugia malayi TAR-binding protein 0.0469 0.1362 0.2571
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0083 0.0277
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0035 0.0047 0.0073
Brugia malayi isocitrate dehydrogenase 0.0049 0.0089 0.0168
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0264 0.074 0.1397
Brugia malayi Pre-SET motif family protein 0.0841 0.249 0.4702
Plasmodium vivax hypothetical protein, conserved 0.0264 0.074 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0099 0.024 0.0454
Loa Loa (eye worm) hypothetical protein 0.0038 0.0057 0.0107
Giardia lamblia DINP protein human, muc B family 0.0041 0.0065 0.0323
Plasmodium vivax hypothetical protein, conserved 0.0047 0.0083 0.1016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.0083 0.0277
Echinococcus multilocularis lamin 0.0027 0.0024 0.0024
Plasmodium falciparum glutathione reductase 0.0028 0.0027 0.0374
Echinococcus granulosus histone lysine methyltransferase setb 0.0138 0.0359 0.0554
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0065 0.0138 0.1762
Toxoplasma gondii PHD-finger domain-containing protein 0.0119 0.0301 0.4028
Loa Loa (eye worm) latrophilin receptor protein 2 0.0197 0.0537 0.1013
Schistosoma mansoni survival motor neuron protein 0.0102 0.0249 0.0384
Schistosoma mansoni chromobox protein 0.0047 0.0083 0.0128
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0596 0.1747 0.614
Echinococcus granulosus Smad4 0.012 0.0306 0.0472
Trypanosoma cruzi target of rapamycin kinase 3 0.0055 0.0108 0.1427
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0065 0.0138 0.1825

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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