Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0153 | 0.288 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0153 | 0.288 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.292 | 0.3938 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0078 | 0.132 | 0.127 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0021 | 0.0155 | 0.1768 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0021 | 0.0155 | 0.0765 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.0765 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0111 | 0.2004 | 0.5783 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0235 | 0.0316 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0017 | 0.0072 | 0.0049 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0017 | 0.0072 | 0.1446 |
Schistosoma mansoni | ap endonuclease | 0.0017 | 0.0072 | 0.0042 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0017 | 0.0072 | 0.0049 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.1631 | 0.4775 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.0765 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0235 | 0.0316 |
Echinococcus multilocularis | dna polymerase kappa | 0.0021 | 0.0155 | 0.0293 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.1059 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0078 | 0.132 | 0.4473 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0017 | 0.0058 | 0.0319 |
Onchocerca volvulus | 0.0078 | 0.132 | 0.5 | |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0017 | 0.0072 | 0.0111 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0025 | 0.0235 | 0.0316 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.004 | 0.0539 | 0.1461 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0153 | 0.288 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0017 | 0.0072 | 0.0426 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.1059 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.288 | 0.3884 |
Echinococcus multilocularis | smad | 0.0025 | 0.0235 | 0.0536 |
Toxoplasma gondii | ABC1 family protein | 0.0078 | 0.132 | 0.4473 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.0155 | 0.0293 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0078 | 0.132 | 0.127 |
Brugia malayi | beta-lactamase family protein | 0.0078 | 0.132 | 0.1781 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0078 | 0.132 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0372 | 0.7415 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0078 | 0.132 | 0.4473 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.0155 | 0.0209 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0093 | 0.1631 | 0.2199 |
Brugia malayi | MH2 domain containing protein | 0.0372 | 0.7415 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0049 | 0.0715 | 0.5359 |
Brugia malayi | Smad1 | 0.0025 | 0.0235 | 0.0316 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0017 | 0.0072 | 0.0111 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0049 | 0.0715 | 0.1995 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.1059 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0372 | 0.7415 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.0049 | 0.0715 | 0.2329 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0078 | 0.132 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0153 | 0.288 | 1 |
Mycobacterium leprae | Probable lipase LipE | 0.0078 | 0.132 | 0.2495 |
Schistosoma mansoni | Smad4 | 0.0025 | 0.0235 | 0.0536 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.1631 | 0.4775 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0017 | 0.0072 | 0.0111 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0021 | 0.0155 | 0.0293 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.004 | 0.0539 | 0.1461 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0078 | 0.132 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.1059 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.132 | 0.127 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0539 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0155 | 0.1059 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0017 | 0.0072 | 0.0111 |
Brugia malayi | Muscleblind-like protein | 0.0155 | 0.292 | 0.3938 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0153 | 0.288 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0078 | 0.132 | 0.4473 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0123 | 0.226 | 0.2214 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0049 | 0.0715 | 0.2329 |
Brugia malayi | Thioredoxin reductase | 0.0049 | 0.0715 | 0.0965 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0111 | 0.2004 | 0.1957 |
Schistosoma mansoni | ap endonuclease | 0.0017 | 0.0072 | 0.0042 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.132 | 0.127 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.1631 | 0.4775 |
Echinococcus multilocularis | muscleblind protein | 0.0155 | 0.292 | 0.869 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0021 | 0.0155 | 0.0097 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0049 | 0.0715 | 0.5206 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0017 | 0.0072 | 0.0042 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.1059 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.3351 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0021 | 0.0155 | 0.0209 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.014 | 0.2602 | 0.7724 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0025 | 0.0235 | 0.0536 |
Mycobacterium ulcerans | beta-lactamase | 0.0078 | 0.132 | 0.4473 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0.0155 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.1631 | 0.4775 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0129 | 0.2387 | 0.7072 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0078 | 0.132 | 0.127 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.0765 |
Brugia malayi | hypothetical protein | 0.004 | 0.0539 | 0.0727 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0025 | 0.0235 | 0.0536 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0155 | 0.1059 |
Plasmodium vivax | glutathione reductase, putative | 0.0049 | 0.0715 | 0.2329 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0078 | 0.132 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.132 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0053 | 0.0802 | 0.2636 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0021 | 0.0155 | 0.0765 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0021 | 0.0155 | 0.0097 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0153 | 0.288 | 0.8568 |
Echinococcus multilocularis | dna polymerase eta | 0.0021 | 0.0155 | 0.0293 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0078 | 0.132 | 0.3833 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.1631 | 0.4775 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0539 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0235 | 0.0536 |
Echinococcus granulosus | dna polymerase kappa | 0.0021 | 0.0155 | 0.0293 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0078 | 0.132 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0017 | 0.0072 | 0.0049 |
Brugia malayi | Probable ClpP-like protease | 0.0153 | 0.288 | 0.3884 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0155 | 0.292 | 0.869 |
Toxoplasma gondii | exonuclease III APE | 0.0017 | 0.0072 | 0.0049 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0017 | 0.0058 | 0.0319 |
Echinococcus granulosus | peptidase Clp S14 family | 0.01 | 0.1788 | 0.5252 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.132 | 0.1781 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.1059 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0021 | 0.0155 | 0.0209 |
Brugia malayi | glutathione reductase | 0.0049 | 0.0715 | 0.0965 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0129 | 0.2387 | 0.7072 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0078 | 0.132 | 0.127 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0053 | 0.0802 | 0.2636 |
Mycobacterium ulcerans | hypothetical protein | 0.0078 | 0.132 | 0.4473 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0049 | 0.0715 | 0.1995 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0153 | 0.288 | 1 |
Echinococcus multilocularis | Smad4 | 0.0025 | 0.0235 | 0.0536 |
Schistosoma mansoni | hypothetical protein | 0.0129 | 0.2387 | 0.7072 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0021 | 0.0155 | 0.0765 |
Trypanosoma brucei | unspecified product | 0.0021 | 0.0155 | 0.1059 |
Trichomonas vaginalis | esterase, putative | 0.0078 | 0.132 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0235 | 0.0536 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.1059 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.132 | 1 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.0155 | 0.0765 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0093 | 0.1631 | 0.2199 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.132 | 0.1781 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0153 | 0.288 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0078 | 0.132 | 0.1781 |
Plasmodium vivax | hypothetical protein, conserved | 0.0078 | 0.132 | 0.4473 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0153 | 0.288 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0111 | 0.2004 | 0.1957 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0539 | 1 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0078 | 0.132 | 0.3833 |
Echinococcus granulosus | geminin | 0.0176 | 0.3351 | 1 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.01 | 0.1788 | 0.5252 |
Schistosoma mansoni | thyroid hormone receptor | 0.014 | 0.2602 | 0.7724 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0153 | 0.288 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0078 | 0.132 | 0.127 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.0765 |
Loa Loa (eye worm) | glutathione reductase | 0.0049 | 0.0715 | 0.0965 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.0058 | 0.0319 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0025 | 0.0235 | 0.0536 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.132 | 0.1781 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0017 | 0.0072 | 0.0014 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0025 | 0.0235 | 0.0536 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0017 | 0.0072 | 0.0111 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0017 | 0.0072 | 0.0097 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.3351 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.0058 | 0.0319 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0078 | 0.132 | 0.1781 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0017 | 0.0072 | 0.0049 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0017 | 0.0072 | 0.0097 |
Leishmania major | DNA polymerase eta, putative | 0.0021 | 0.0155 | 0.0765 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0111 | 0.2004 | 0.1957 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0123 | 0.226 | 0.7015 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0049 | 0.0715 | 0.0965 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.0155 | 0.0342 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.004 | 0.0539 | 0.1461 |
Toxoplasma gondii | hypothetical protein | 0.0053 | 0.0802 | 0.2636 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0025 | 0.0235 | 0.0536 |
Brugia malayi | beta-lactamase | 0.0078 | 0.132 | 0.1781 |
Mycobacterium tuberculosis | Probable reductase | 0.0111 | 0.2004 | 0.1957 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0053 | 0.0802 | 0.2636 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.132 | 0.1781 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.1631 | 0.4775 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.1059 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0078 | 0.132 | 0.127 |
Brugia malayi | beta-lactamase family protein | 0.0078 | 0.132 | 0.1781 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0153 | 0.288 | 0.8568 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.1059 |
Leishmania major | hypothetical protein, conserved | 0.0078 | 0.132 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0025 | 0.0235 | 0.0316 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0078 | 0.132 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.132 | 0.1781 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0153 | 0.288 | 1 |
Leishmania major | trypanothione reductase | 0.0049 | 0.0715 | 0.5206 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0078 | 0.132 | 0.3833 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.01 | 0.1788 | 0.174 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0111 | 0.2004 | 0.1957 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0049 | 0.0715 | 0.0661 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0017 | 0.0072 | 0.0049 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0078 | 0.132 | 0.3833 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0539 | 0.1461 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0153 | 0.288 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0021 | 0.0155 | 0.0293 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0235 | 0.0536 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.0058 | 0.0078 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.01 | 0.1788 | 0.174 |
Plasmodium falciparum | thioredoxin reductase | 0.0049 | 0.0715 | 0.2329 |
Loa Loa (eye worm) | Smad1 | 0.0025 | 0.0235 | 0.0316 |
Schistosoma mansoni | thyroid hormone receptor | 0.014 | 0.2602 | 0.7724 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0021 | 0.0155 | 0.1059 |
Onchocerca volvulus | 0.0078 | 0.132 | 0.5 | |
Plasmodium falciparum | glutathione reductase | 0.0049 | 0.0715 | 0.2329 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0153 | 0.288 | 0.8568 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0123 | 0.226 | 0.2214 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.0765 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0078 | 0.132 | 0.127 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0021 | 0.0155 | 0.1059 |
Echinococcus granulosus | muscleblind protein | 0.0155 | 0.292 | 0.869 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0021 | 0.0155 | 0.0293 |
Schistosoma mansoni | smad | 0.0025 | 0.0235 | 0.0536 |
Schistosoma mansoni | DNA polymerase eta | 0.0021 | 0.0155 | 0.0293 |
Echinococcus granulosus | smad | 0.0025 | 0.0235 | 0.0536 |
Echinococcus multilocularis | geminin | 0.0176 | 0.3351 | 1 |
Echinococcus granulosus | Smad4 | 0.0025 | 0.0235 | 0.0536 |
Onchocerca volvulus | 0.0078 | 0.132 | 0.5 | |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0078 | 0.132 | 0.127 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.132 | 0.1781 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0021 | 0.0155 | 0.0293 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0155 | 0.0209 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0111 | 0.2004 | 0.1957 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.01 | 0.1788 | 0.4744 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0235 | 0.0316 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0017 | 0.0072 | 0.0042 |
Loa Loa (eye worm) | beta-lactamase | 0.0078 | 0.132 | 0.1781 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.1631 | 0.4775 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0021 | 0.0155 | 0.0342 |
Mycobacterium leprae | conserved hypothetical protein | 0.0078 | 0.132 | 0.2495 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0539 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.292 | 0.3938 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0235 | 0.0316 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0155 | 0.1059 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0123 | 0.226 | 0.2214 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 89.1251 uM | PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.