Detailed information for compound 1180953

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 639.708 | Formula: C25H45N13O7
  • H donors: 11 H acceptors: 8 LogP: -7.58 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 3
  • SMILES: NCCN(C(=O)Cn1cnc2c1ncnc2N)CC(=O)NCCN[C@H]1[C@@H](O)[C@H](N)C[C@@H]([C@H]1O[C@H]1O[C@H](CN)[C@H]([C@@H]([C@H]1N)O)O)N
  • InChi: 1S/C25H45N13O7/c26-1-4-37(15(40)8-38-10-36-18-23(31)34-9-35-24(18)38)7-14(39)32-2-3-33-17-19(41)11(28)5-12(29)22(17)45-25-16(30)21(43)20(42)13(6-27)44-25/h9-13,16-17,19-22,25,33,41-43H,1-8,26-30H2,(H,32,39)(H2,31,34,35)/t11-,12+,13-,16-,17+,19+,20-,21-,22-,25-/m1/s1
  • InChiKey: WCQWQNGHEKUGQL-KZLTUPNSSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0388 0.1056 0.2194
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0063 0.0104 0.1776
Echinococcus multilocularis chromobox protein 1 0.007 0.0125 0.0119
Mycobacterium tuberculosis Probable hydrolase 0.0074 0.0135 0.0096
Mycobacterium ulcerans hypothetical protein 0.0074 0.0135 0.0931
Trypanosoma brucei hypothetical protein, conserved 0.0074 0.0135 0.2414
Loa Loa (eye worm) MH2 domain-containing protein 0.036 0.0973 0.1614
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.012 0.0271 0.0266
Echinococcus granulosus TRP transient receptor potential channel 0.0038 0.0031 0.0053
Echinococcus multilocularis jumonji domain containing 1A 0.0038 0.0031 0.0026
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.0199 0.0323
Brugia malayi Pre-SET motif family protein 0.0456 0.1257 0.2084
Schistosoma mansoni transcription factor LCR-F1 0.0115 0.0255 0.0522
Trichomonas vaginalis glucosylceramidase, putative 0.2079 0.6011 1
Schistosoma mansoni peptidase Clp (S14 family) 0.008 0.0154 0.0309
Loa Loa (eye worm) hypothetical protein 0.005 0.0067 0.0104
Leishmania major CAAX prenyl protease 1, putative,metallo-peptidase, Clan M-, Family M48 0.0068 0.0119 0.1858
Echinococcus multilocularis transient receptor potential ion channel A 0.0099 0.0209 0.0203
Echinococcus granulosus transient receptor potential ion channel A 0.0099 0.0209 0.0425
Brugia malayi Calcitonin receptor-like protein seb-1 0.0769 0.2173 0.361
Brugia malayi isocitrate dehydrogenase 0.0063 0.0104 0.0164
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0135 0.0271
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0038 0.0032 0.0044
Loa Loa (eye worm) hypothetical protein 0.0111 0.0245 0.0402
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0116 0.026 0.0223
Brugia malayi jmjC domain containing protein 0.0388 0.1056 0.175
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0154 0.1113
Toxoplasma gondii isocitrate dehydrogenase 0.0063 0.0104 0.1743
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0039 0.0071
Trichomonas vaginalis glucosylceramidase, putative 0.1364 0.3916 0.6515
Loa Loa (eye worm) hypothetical protein 0.0096 0.0199 0.0326
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0063 0.0104 0.1776
Echinococcus multilocularis jumonji domain containing protein 0.0165 0.0402 0.0397
Echinococcus multilocularis peregrin 0.0126 0.0288 0.0283
Toxoplasma gondii LsmAD domain-containing protein 0.0079 0.0152 0.2546
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0152 0.5697
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0389 0.1059 0.3229
Brugia malayi hypothetical protein 0.0146 0.0348 0.057
Brugia malayi glutathione reductase 0.0046 0.0054 0.0081
Leishmania major hypothetical protein, conserved 0.0074 0.0135 0.2188
Brugia malayi hypothetical protein 0.0115 0.0255 0.0416
Trypanosoma brucei metallo- peptidase, Clan M- Family M48 0.0068 0.0119 0.2093
Toxoplasma gondii CAAX amino terminal protease family protein 0.0041 0.004 0.0675
Loa Loa (eye worm) hypothetical protein 0.0118 0.0265 0.0436
Toxoplasma gondii PHD-finger domain-containing protein 0.0118 0.0266 0.4469
Plasmodium vivax ataxin-2 like protein, putative 0.0079 0.0152 0.5697
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0073 0.0141
Brugia malayi calpain family protein 1 0.0063 0.0104 0.0165
Plasmodium vivax SET domain protein, putative 0.0068 0.0118 0.4411
Loa Loa (eye worm) PHD-finger family protein 0.0064 0.0105 0.0169
Trichomonas vaginalis Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase 0.0068 0.0119 0.0197
Echinococcus granulosus beta LACTamase domain containing family member 0.0074 0.0135 0.0271
Onchocerca volvulus 0.0079 0.0151 0.0373
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.02 0.0505 0.1044
Schistosoma mansoni farnesylated-protein converting enzyme 1 (M48 family) 0.0068 0.0119 0.0238
Brugia malayi Transient-receptor-potential like protein 0.0038 0.0031 0.0042
Schistosoma mansoni hypothetical protein 0.0526 0.146 0.3037
Echinococcus granulosus chromobox protein 1 0.007 0.0125 0.0249
Echinococcus granulosus jumonji domain containing protein 0.0165 0.0402 0.0829
Brugia malayi Heterochromatin protein 1 0.007 0.0125 0.0199
Brugia malayi jmjC domain containing protein 0.0038 0.0031 0.0043
Toxoplasma gondii PHD-finger domain-containing protein 0.0039 0.0033 0.0549
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0076
Plasmodium vivax hypothetical protein, conserved 0.0118 0.0266 1
Echinococcus granulosus dnaJ subfamily B 0.1664 0.4796 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0114 0.0227
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0116 0.026 0.0223
Brugia malayi beta-lactamase 0.0074 0.0135 0.0216
Loa Loa (eye worm) hypothetical protein 0.0074 0.0135 0.0219
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.008 0.0154 0.5763
Loa Loa (eye worm) hypothetical protein 0.0051 0.007 0.0109
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0063 0.0104 0.0206
Echinococcus granulosus lysine specific demethylase 6a 0.0038 0.0031 0.0054
Onchocerca volvulus Glucosylceramidase homolog 0.1364 0.3916 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0079 0.0152 0.5697
Loa Loa (eye worm) hypothetical protein 0.0079 0.0152 0.0246
Brugia malayi Peptidase family M48 containing protein 0.0068 0.0119 0.019
Schistosoma mansoni protein phosphatase 2C 0.0038 0.0031 0.0054
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0197 0.04
Toxoplasma gondii PHD-finger domain-containing protein 0.0118 0.0266 0.4469
Schistosoma mansoni transient receptor potential channel 4 0.0102 0.0219 0.0445
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0046 0.0054 0.0014
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0379 0.1031 1
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.0154 0.1113
Onchocerca volvulus 0.0053 0.0073 0.0174
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0038 0.0032 0.0044
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.003 0.0049
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0038 0.0032 0.0052
Schistosoma mansoni patched 1 0.0041 0.0039 0.0071
Giardia lamblia DNA repair protein RAD52 0.0379 0.1031 1
Entamoeba histolytica CAAX amino terminal protease family 0.0041 0.004 0.0085
Plasmodium vivax protease, putative 0.0041 0.004 0.151
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0135 0.0223
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0063 0.0104 0.1776
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0052 0.0073 0.0068
Trypanosoma cruzi peptidase with unknown catalytic mechanism (family U48) 0.02 0.0505 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0068 0.0118 0.1971
Schistosoma mansoni hypothetical protein 0.0118 0.0266 0.0545
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0043 0.0097
Echinococcus multilocularis caax prenyl protease 1 0.0068 0.0119 0.0114
Mycobacterium tuberculosis Probable reductase 0.0105 0.0226 0.0188
Brugia malayi PHD-finger family protein 0.0118 0.0266 0.0435
Echinococcus granulosus calpain A 0.0066 0.0114 0.0227
Mycobacterium tuberculosis Probable oxidoreductase 0.0116 0.026 0.0223
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0115 0.0255 0.0522
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.2079 0.6011 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0063 0.0104 0.0099
Trichomonas vaginalis Clan U, family U48, CaaX prenyl peptidase 2-like 0.02 0.0505 0.084
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.003 0.0049
Echinococcus multilocularis short transient receptor potential channel 6 0.0068 0.0117 0.0112
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.003 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0135 0.2414
Mycobacterium tuberculosis Conserved protein 0.0074 0.0135 0.0096
Echinococcus multilocularis neuropeptide receptor A26 0.0454 0.1248 0.1244
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0063 0.0104 0.0099
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.008 0.0154 0.0309
Echinococcus multilocularis neuropeptide s receptor 0.0454 0.1248 0.1244
Loa Loa (eye worm) latrophilin receptor protein 2 0.0243 0.0632 0.1047
Entamoeba histolytica CAAX prenyl protease family 0.02 0.0505 0.4739
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0079 0.0151 0.0304
Loa Loa (eye worm) hypothetical protein 0.0074 0.0135 0.0219
Schistosoma mansoni hypothetical protein 0.004 0.0035 0.0062
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0039 0.0032 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.0271 0.0555
Schistosoma mansoni survival motor neuron protein 0.0053 0.0073 0.0142
Echinococcus multilocularis survival motor neuron protein 1 0.0258 0.0674 0.0669
Entamoeba histolytica hypothetical protein 0.0108 0.0236 0.204
Echinococcus multilocularis transient receptor potential gamma protein 0.0102 0.0219 0.0213
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0108 0.0236 0.204
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0112 0.0247 0.0402
Mycobacterium leprae conserved hypothetical protein 0.0074 0.0135 0.0412
Echinococcus granulosus cpg binding protein 0.0129 0.0298 0.0612
Echinococcus granulosus histone lysine methyltransferase setb 0.012 0.0271 0.0555
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0769 0.2173 0.3612
Schistosoma mansoni chromobox protein 0.007 0.0125 0.0249
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0063 0.0104 0.3901
Leishmania major hypothetical protein, conserved 0.0079 0.0152 0.2541
Schistosoma mansoni jumonji/arid domain-containing protein 0.0156 0.0376 0.0774
Brugia malayi Bromodomain containing protein 0.0126 0.0288 0.047
Echinococcus granulosus microtubule associated protein 2 0.0705 0.1987 0.4136
Brugia malayi latrophilin 2 splice variant baaae 0.0526 0.146 0.2422
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0063 0.0104 0.0206
Brugia malayi beta-lactamase family protein 0.0074 0.0135 0.0216
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0066 0.0114 0.0227
Schistosoma mansoni hypothetical protein 0.0243 0.0632 0.1309
Plasmodium vivax hypothetical protein, conserved 0.0074 0.0135 0.5069
Schistosoma mansoni cpg binding protein 0.0117 0.0262 0.0535
Echinococcus granulosus short transient receptor potential channel 6 0.0068 0.0117 0.0234
Echinococcus granulosus CAAX prenyl protease 2 0.02 0.0505 0.1044
Brugia malayi jmjC domain containing protein 0.0156 0.0376 0.0618
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0074 0.0135 0.0931
Brugia malayi CHE-14 protein 0.0041 0.0039 0.0057
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0034 0.0074
Echinococcus granulosus short transient receptor potential channel 6 0.0068 0.0117 0.0234
Schistosoma mansoni zinc finger protein 0.0047 0.0057 0.0108
Entamoeba histolytica CAAX prenyl protease, putative 0.0068 0.0119 0.0877
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0197 0.0192
Loa Loa (eye worm) PHD-finger family protein 0.0118 0.0266 0.0437
Loa Loa (eye worm) hypothetical protein 0.008 0.0154 0.0249
Toxoplasma gondii thioredoxin reductase 0.0046 0.0054 0.0903
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0039 0.0064
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.008 0.0154 0.0148
Mycobacterium leprae Conserved hypothetical protein 0.1147 0.3279 1
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.0199 0.0405
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0073 0.0222
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0135 0.0223
Echinococcus granulosus geminin 0.1392 0.3997 0.8334
Loa Loa (eye worm) hypothetical protein 0.0039 0.0034 0.0051
Brugia malayi Bromodomain containing protein 0.0118 0.0265 0.0432
Echinococcus granulosus lysine specific demethylase 5A 0.0156 0.0376 0.0774
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0034 0.0056
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0031 0.0046
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0154 0.2575
Onchocerca volvulus 0.0074 0.0135 0.0332
Loa Loa (eye worm) hypothetical protein 0.012 0.0271 0.0445
Schistosoma mansoni jumonji domain containing protein 0.0038 0.0031 0.0054
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.0199 0.1677
Trichomonas vaginalis glucosylceramidase, putative 0.1364 0.3916 0.6515
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0039 0.0032 0.0027
Leishmania major hypothetical protein, conserved 0.0047 0.0057 0.0547
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0038 0.0031 0.0289
Loa Loa (eye worm) glutathione reductase 0.0046 0.0054 0.0083
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0038 0.0031 0.0526
Schistosoma mansoni jumonji domain containing protein 0.0308 0.0823 0.1706
Echinococcus multilocularis chromobox protein 1 0.007 0.0125 0.0119
Brugia malayi chromobox protein homolog 3 0.0039 0.0034 0.0048
Trichomonas vaginalis esterase, putative 0.0074 0.0135 0.0223
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0068 0.0118 0.0112
Loa Loa (eye worm) twinkle helicase 0.0111 0.0245 0.0401
Schistosoma mansoni hypothetical protein 0.0036 0.0024 0.0038
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0034 0.0056
Brugia malayi Pre-SET motif family protein 0.0068 0.0118 0.0187
Echinococcus multilocularis phd:f box containing protein 0.0038 0.0031 0.0026
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0105 0.0226 0.0188
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0039 0.0033 0.0318
Loa Loa (eye worm) hypothetical protein 0.0044 0.0049 0.0076
Brugia malayi MH2 domain containing protein 0.036 0.0973 0.1612
Trichomonas vaginalis glucosylceramidase, putative 0.2079 0.6011 1
Mycobacterium ulcerans lipase LipD 0.0074 0.0135 0.0931
Schistosoma mansoni phd/f-box containing protein 0.0038 0.0031 0.0054
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0054 0.2013
Brugia malayi calpain family protein 1 0.0063 0.0104 0.0165
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0389 0.1059 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0063 0.0104 0.1776
Echinococcus multilocularis transcription factor eb 0.0112 0.0247 0.0242
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0031 0.0011 0.0006
Onchocerca volvulus 0.0031 0.001 0.0011
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0063 0.0103 0.0204
Trypanosoma cruzi hypothetical protein, conserved 0.0074 0.0135 0.2414
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0111 0.0243 0.0497
Schistosoma mansoni hypothetical protein 0.0047 0.0057 0.0108
Brugia malayi jmjC domain containing protein 0.0038 0.0031 0.0043
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0073 0.0033
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0076 0.0142 0.0137
Brugia malayi CXXC zinc finger family protein 0.0117 0.0262 0.0427
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0105 0.0226 0.0188
Echinococcus multilocularis calpain A 0.0066 0.0114 0.0109
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0038 0.0031 0.0526
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0038 0.0032 0.0298
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0388 0.1056 0.1052
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0038 0.0032 0.0047
Loa Loa (eye worm) hypothetical protein 0.0049 0.0064 0.0099
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0031 0.0046
Trichomonas vaginalis glucosylceramidase, putative 0.1364 0.3916 0.6515
Leishmania major CAAX prenyl protease 2, putative,peptidase with unknown catalytic mechanism (family U48) 0.02 0.0505 1
Echinococcus granulosus phd:f box containing protein 0.0038 0.0031 0.0054
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0066 0.0114 0.0227
Echinococcus multilocularis calpain family protein 1, d 0.0044 0.0049 0.0044
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0031 0.0046
Loa Loa (eye worm) hypothetical protein 0.0074 0.0135 0.0219
Entamoeba histolytica CAAX amino terminal protease family 0.0041 0.004 0.0085
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0073 0.0113
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0135 0.0223
Plasmodium falciparum phd finger protein, putative 0.0118 0.0266 1
Onchocerca volvulus 0.0519 0.1441 0.367
Echinococcus multilocularis microtubule associated protein 2 0.0705 0.1987 0.1982
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0074 0.0135 0.0219
Echinococcus granulosus transcription factor eb 0.0112 0.0247 0.0504
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0051 0.0068 0.0063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.003 0.0049
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0109 0.0238 0.0724
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0039 0.0033 0.0318
Loa Loa (eye worm) hypothetical protein 0.0038 0.0031 0.0046
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0109 0.0238 0.0927
Echinococcus granulosus jumonji domain containing 1A 0.0038 0.0031 0.0054
Onchocerca volvulus Alhambra homolog 0.0118 0.0266 0.0668
Echinococcus granulosus mixed lineage leukemia protein mll 0.0031 0.0011 0.0012
Loa Loa (eye worm) hypothetical protein 0.0769 0.2173 0.3612
Trypanosoma cruzi ISWI complex protein 0.0047 0.0057 0.082
Chlamydia trachomatis replicative DNA helicase 0.0389 0.1059 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0038 0.003 0.0049
Mycobacterium tuberculosis Probable lipase LipE 0.0074 0.0135 0.0096
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0073 0.0141
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0005 0.0003
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.2079 0.6011 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.0038 0.0031 0.1176
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0043 0.0071
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.019 0.0477 0.0472
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0038 0.0031 0.0025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.025 0.0653 0.1351
Trichomonas vaginalis penicillin-binding protein, putative 0.0074 0.0135 0.0223
Entamoeba histolytica hypothetical protein 0.0115 0.0255 0.2238
Mycobacterium tuberculosis Possible penicillin-binding protein 0.047 0.1298 0.1274
Echinococcus multilocularis thioredoxin glutathione reductase 0.0046 0.0054 0.0048
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0111 0.0245 0.0402
Schistosoma mansoni hypothetical protein 0.1392 0.3997 0.8334
Echinococcus granulosus PHD finger protein rhinoceros 0.0118 0.0266 0.0545
Loa Loa (eye worm) histone methyltransferase 0.0039 0.0032 0.0047
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.0197 0.0319
Schistosoma mansoni hypothetical protein 0.1664 0.4796 1
Echinococcus multilocularis geminin 0.1392 0.3997 0.3994
Echinococcus multilocularis protein patched 0.0041 0.0039 0.0034
Loa Loa (eye worm) hypothetical protein 0.0063 0.0104 0.0168
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0031 0.0011 0.0012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0063 0.0104 0.0099
Loa Loa (eye worm) beta-lactamase 0.0074 0.0135 0.0219
Mycobacterium tuberculosis Probable esterase LipL 0.0074 0.0135 0.0096
Trichomonas vaginalis Clan MA, family M48, Ste24 endopeptidase-like metallopeptidase 0.0068 0.0119 0.0197
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0063 0.0104 0.0099
Toxoplasma gondii histone lysine methyltransferase SET1 0.0231 0.0596 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.0135 0.0219
Leishmania major trypanothione reductase 0.0046 0.0054 0.0474
Toxoplasma gondii CAAX metallo endopeptidase 0.0068 0.0119 0.2003
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0152 0.2757
Trypanosoma cruzi CAAX prenyl protease 1, putative 0.0068 0.0119 0.2093
Loa Loa (eye worm) hypothetical protein 0.0526 0.146 0.2424
Brugia malayi Isocitrate dehydrogenase 0.0063 0.0104 0.0164
Echinococcus granulosus JmjC domain containing protein 4 0.0038 0.0031 0.0054
Loa Loa (eye worm) hypothetical protein 0.0063 0.0104 0.0168
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.032 0.0314
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0051 0.0068 0.0131
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0066 0.0114 0.0109
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0068 0.0118 0.0234
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.003 0.0049
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0038 0.0031 0.0289
Trichomonas vaginalis set domain proteins, putative 0.0519 0.1441 0.2396
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0105 0.0226 0.0188
Trypanosoma brucei PAB1-binding protein , putative 0.0079 0.0152 0.2757
Loa Loa (eye worm) hypothetical protein 0.0038 0.0031 0.0045
Echinococcus granulosus methyl CpG binding domain protein 2 0.0052 0.0073 0.0141
Trichomonas vaginalis D-aminoacylase, putative 0.0074 0.0135 0.0223
Loa Loa (eye worm) transcription factor SMAD2 0.036 0.0973 0.1614
Echinococcus granulosus expressed conserved protein 0.009 0.0182 0.037
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0038 0.0031 0.0054
Loa Loa (eye worm) CXXC zinc finger family protein 0.0117 0.0262 0.0429
Echinococcus multilocularis lysine specific demethylase 5A 0.0143 0.034 0.0334
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.0199 0.0194
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0063 0.0104 0.3901
Loa Loa (eye worm) hypothetical protein 0.0038 0.0031 0.0046
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0125 0.0249
Loa Loa (eye worm) hypothetical protein 0.0203 0.0514 0.085
Schistosoma mansoni hypothetical protein 0.0243 0.0632 0.1309
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0036 0.0024 0.0038
Schistosoma mansoni hypothetical protein 0.0064 0.0105 0.0209
Echinococcus multilocularis lysine specific demethylase 6a 0.0038 0.0031 0.0026
Loa Loa (eye worm) jmjC domain-containing protein 0.0245 0.0636 0.1053
Schistosoma mansoni chromobox protein 0.007 0.0125 0.0249
Plasmodium vivax glutathione reductase, putative 0.0046 0.0054 0.202
Loa Loa (eye worm) hypothetical protein 0.0031 0.001 0.001
Schistosoma mansoni cpg binding protein 0.0129 0.0298 0.0612
Trichomonas vaginalis glucosylceramidase, putative 0.1364 0.3916 0.6515
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0197 0.04
Brugia malayi Thioredoxin reductase 0.0046 0.0054 0.0081
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0005 0.0003
Brugia malayi hypothetical protein 0.0079 0.0152 0.0244
Plasmodium falciparum thioredoxin reductase 0.0046 0.0054 0.202
Echinococcus granulosus caax prenyl protease 1 0.0068 0.0119 0.0238
Loa Loa (eye worm) hypothetical protein 0.0035 0.0021 0.0028
Trypanosoma brucei ISWI complex protein 0.0047 0.0057 0.082
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0063 0.0104 0.0065
Loa Loa (eye worm) bromodomain containing protein 0.0054 0.0079 0.0125
Schistosoma mansoni hypothetical protein 0.1392 0.3997 0.8334
Loa Loa (eye worm) hypothetical protein 0.0243 0.0632 0.1047
Loa Loa (eye worm) calpain family protein 1 0.0063 0.0104 0.0168
Brugia malayi hypothetical protein 0.0258 0.0674 0.1114
Schistosoma mansoni methyl-cpg binding protein mbd 0.0052 0.0073 0.0141
Echinococcus granulosus neuropeptide s receptor 0.0454 0.1248 0.2595
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.313 0.9092 0.9168
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.003 0.0049
Schistosoma mansoni family U48 unassigned peptidase (U48 family) 0.02 0.0505 0.1044
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0197 0.04
Echinococcus granulosus thioredoxin glutathione reductase 0.0046 0.0054 0.0101
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0031 0.0011 0.0006
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0063 0.0104 0.1531
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0038 0.0032 0.0047
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0039 0.0059
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0039 0.0071
Mycobacterium ulcerans recombinase A 0.0109 0.0238 0.1937
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0389 0.1059 1
Schistosoma mansoni hypothetical protein 0.004 0.0035 0.0062
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0038 0.003 0.0049
Echinococcus multilocularis GPCR, family 2 0.0243 0.0632 0.0627
Onchocerca volvulus 0.0074 0.0135 0.0332
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0036 0.0024 0.0018
Loa Loa (eye worm) hypothetical protein 0.0125 0.0287 0.0471
Onchocerca volvulus 0.0146 0.0348 0.0875
Loa Loa (eye worm) hypothetical protein 0.0218 0.0557 0.0921
Mycobacterium tuberculosis Conserved protein 0.0074 0.0135 0.0096
Treponema pallidum hypothetical protein 0.0041 0.004 0.038
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.019 0.0477 0.0985
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.008 0.0154 0.5763
Echinococcus multilocularis cpg binding protein 0.0129 0.0298 0.0293
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0154 0.1113
Trichomonas vaginalis chromobox protein, putative 0.007 0.0125 0.0206
Toxoplasma gondii hypothetical protein 0.0041 0.004 0.0675
Mycobacterium ulcerans beta-lactamase 0.0074 0.0135 0.0931
Schistosoma mansoni transient receptor potential channel 0.0102 0.0219 0.0445
Brugia malayi AF-10 protein 0.0039 0.0033 0.0046
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.0197 0.04
Loa Loa (eye worm) thioredoxin reductase 0.0046 0.0054 0.0083
Trichomonas vaginalis glucosylceramidase, putative 0.2079 0.6011 1
Echinococcus multilocularis isocitrate dehydrogenase 0.0063 0.0104 0.0099
Loa Loa (eye worm) hypothetical protein 0.0258 0.0674 0.1116
Brugia malayi PHD-finger family protein 0.0051 0.007 0.0107
Brugia malayi CAAX amino terminal protease family protein 0.02 0.0505 0.0833
Plasmodium vivax thioredoxin reductase, putative 0.0046 0.0054 0.202
Trichomonas vaginalis glucosylceramidase, putative 0.2079 0.6011 1
Chlamydia trachomatis recombinase RecA 0.0109 0.0238 0.1937
Echinococcus granulosus zinc finger protein 0.0067 0.0115 0.023
Echinococcus multilocularis JmjC domain containing protein 4 0.0038 0.0031 0.0026
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0111 0.0243 0.0238
Schistosoma mansoni phosphatidylserine receptor 0.0038 0.0031 0.0054
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0038 0.0032 0.0026
Echinococcus multilocularis protein dispatched 1 0.0047 0.0056 0.0051
Mycobacterium tuberculosis Probable dehydrogenase 0.0105 0.0226 0.0188
Mycobacterium tuberculosis Conserved protein 0.0074 0.0135 0.0096
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0243 0.0632 0.1309
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0243 0.0632 0.1309
Echinococcus multilocularis tumor protein p63 0.0336 0.0905 0.09
Echinococcus multilocularis beta LACTamase domain containing family member 0.0074 0.0135 0.013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.012 0.0271 0.0555
Onchocerca volvulus 0.0044 0.0049 0.0112
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.0154 0.2575
Entamoeba histolytica hypothetical protein 0.0115 0.0255 0.2238
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0039 0.0033 0.0549
Trypanosoma brucei CAAX amino terminal protease, putative 0.02 0.0505 1
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0039 0.0034
Loa Loa (eye worm) hypothetical protein 0.0102 0.0219 0.0358
Trichomonas vaginalis glucosylceramidase, putative 0.1437 0.4131 0.6873
Treponema pallidum replicative DNA helicase (dnaB) 0.0389 0.1059 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.0204 0.0414
Trichomonas vaginalis glucosylceramidase, putative 0.2079 0.6011 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0243 0.0632 0.0627
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0038 0.0032 0.0009
Trichomonas vaginalis glucosylceramidase, putative 0.1364 0.3916 0.6515
Entamoeba histolytica hypothetical protein 0.0115 0.0255 0.2238
Plasmodium vivax JmjC domain containing protein 0.0038 0.0031 0.1176
Schistosoma mansoni hypothetical protein 0.0039 0.0033 0.0057
Echinococcus multilocularis dnaJ subfamily B 0.1664 0.4796 0.4793
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0243 0.0632 0.0627
Entamoeba histolytica hypothetical protein 0.0115 0.0255 0.2238
Plasmodium falciparum glutathione reductase 0.0046 0.0054 0.202
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.0197 0.04
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.341 0.9913 1
Loa Loa (eye worm) hypothetical protein 0.0138 0.0324 0.0532
Echinococcus granulosus fetal alzheimer antigen falz 0.0076 0.0142 0.0286
Echinococcus multilocularis zinc finger protein 0.0067 0.0115 0.011
Loa Loa (eye worm) hypothetical protein 0.0074 0.0135 0.0219
Schistosoma mansoni transient receptor potential channel 0.0068 0.0117 0.0234
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0074 0.0135 0.0096
Echinococcus granulosus transient receptor potential gamma protein 0.0102 0.0219 0.0445
Loa Loa (eye worm) peptidase family M48 containing protein 0.0068 0.0119 0.0192
Loa Loa (eye worm) hypothetical protein 0.0074 0.0135 0.0219
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0125 0.0201
Loa Loa (eye worm) hypothetical protein 0.0118 0.0266 0.0437
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0076 0.0142 0.0286
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0063 0.0104 0.0207
Plasmodium falciparum protease, putative 0.0041 0.004 0.151
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0038 0.0032 0.0298
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0769 0.2173 0.361
Loa Loa (eye worm) jmjC domain-containing protein 0.0156 0.0376 0.062
Schistosoma mansoni cpg binding protein 0.0129 0.0298 0.0612
Echinococcus granulosus chromobox protein 1 0.007 0.0125 0.0249
Echinococcus multilocularis PHD finger protein rhinoceros 0.0118 0.0266 0.0261
Brugia malayi Latrophilin receptor protein 2 0.0243 0.0632 0.1044
Trypanosoma cruzi ISWI complex protein 0.0047 0.0057 0.082
Schistosoma mansoni hypothetical protein 0.0053 0.0073 0.0142
Schistosoma mansoni jumonji/arid domain-containing protein 0.0156 0.0376 0.0774
Schistosoma mansoni hypothetical protein 0.004 0.0035 0.0062
Loa Loa (eye worm) hypothetical protein 0.0146 0.0348 0.0572
Treponema pallidum recombinase A 0.0109 0.0238 0.2243
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0038 0.0032 0.1193
Schistosoma mansoni microtubule-associated protein tau 0.0705 0.1987 0.4136
Onchocerca volvulus 0.0074 0.0135 0.0332
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.0154 0.1113
Trichomonas vaginalis glucosylceramidase, putative 0.1364 0.3916 0.6515
Mycobacterium ulcerans esterase/lipase LipP 0.0074 0.0135 0.0931
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0064 0.0121
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0038 0.0032 0.0052
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0038 0.0032 0.0298
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0105 0.0226 0.0188
Brugia malayi F/Y-rich N-terminus family protein 0.0083 0.0162 0.026
Onchocerca volvulus 0.0049 0.0064 0.0149
Echinococcus granulosus GPCR family 2 0.0243 0.0632 0.1309
Loa Loa (eye worm) hypothetical protein 0.0029 0.0005 0.0003
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0105 0.0226 0.069
Loa Loa (eye worm) hypothetical protein 0.0064 0.0107 0.0172
Schistosoma mansoni hypothetical protein 0.0243 0.0632 0.1309
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0115 0.0255 0.025
Brugia malayi Probable ClpP-like protease 0.008 0.0154 0.0247
Brugia malayi jmjC domain containing protein 0.0038 0.0031 0.0043
Echinococcus multilocularis expressed conserved protein 0.009 0.0182 0.0177
Echinococcus granulosus neuropeptide receptor A26 0.0454 0.1248 0.2595
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.032 0.0656
Toxoplasma gondii ABC1 family protein 0.0074 0.0135 0.2265
Toxoplasma gondii isocitrate dehydrogenase 0.0063 0.0104 0.1743
Trichomonas vaginalis glucosylceramidase, putative 0.1364 0.3916 0.6515
Brugia malayi PHD-finger family protein 0.0083 0.0164 0.0263
Schistosoma mansoni hypothetical protein 0.004 0.0035 0.0062
Mycobacterium tuberculosis Probable lipase LipD 0.0074 0.0135 0.0096
Trypanosoma brucei trypanothione reductase 0.0046 0.0054 0.0749
Giardia lamblia Hypothetical protein 0.02 0.0505 0.3125
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0073 0.0068
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0038 0.0031 0.0289
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0118 0.0266 0.0545
Brugia malayi jmjC domain containing protein 0.0038 0.0031 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.1437 0.4131 0.6873
Trypanosoma cruzi CAAX prenyl protease 2, putative 0.02 0.0505 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.0197 0.0192
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0074 0.0135 0.0096
Schistosoma mansoni hypothetical protein 0.0115 0.0255 0.0522
Onchocerca volvulus 0.0117 0.0262 0.0655
Schistosoma mansoni Replicative DNA helicase 0.0389 0.1059 0.2199
Mycobacterium leprae Probable lipase LipE 0.0074 0.0135 0.0412
Toxoplasma gondii hypothetical protein 0.0041 0.004 0.0675
Trichomonas vaginalis glucosylceramidase, putative 0.2079 0.6011 1
Brugia malayi Bromodomain containing protein 0.0238 0.0615 0.1016
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0116 0.026 0.0794
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.0197 0.0321
Trypanosoma cruzi trypanothione reductase, putative 0.0046 0.0054 0.0749
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.008 0.0154 0.0468
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0038 0.0032 0.0533
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0038 0.0032 0.0055
Trichomonas vaginalis chromobox protein, putative 0.007 0.0125 0.0206
Echinococcus multilocularis CAAX prenyl protease 2 0.02 0.0505 0.05
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0074 0.0135 0.0096
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0038 0.0032 0.0055
Echinococcus granulosus tumor protein p63 0.0336 0.0905 0.1877
Schistosoma mansoni transient receptor potential channel 0.0068 0.0117 0.0234
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0243 0.0632 0.1044
Brugia malayi hypothetical protein 0.0051 0.0069 0.0107
Brugia malayi beta-lactamase family protein 0.0074 0.0135 0.0216
Loa Loa (eye worm) hypothetical protein 0.0041 0.0039 0.0059
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0038 0.0032 0.1193
Echinococcus granulosus peregrin 0.0126 0.0288 0.059
Loa Loa (eye worm) isocitrate dehydrogenase 0.0063 0.0104 0.0167
Schistosoma mansoni zinc finger protein 0.0067 0.0115 0.023
Echinococcus multilocularis short transient receptor potential channel 6 0.0068 0.0117 0.0112
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0046 0.0054 0.2013
Loa Loa (eye worm) calpain family protein 1 0.0044 0.0049 0.0076
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0043 0.0071
Schistosoma mansoni bromodomain containing protein 0.0201 0.051 0.1053
Trypanosoma cruzi metallo- peptidase, Clan M- Family M48 0.0068 0.0119 0.2093
Trypanosoma cruzi PAB1-binding protein , putative 0.0079 0.0152 0.2757
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.008 0.0154 0.145
Schistosoma mansoni hypothetical protein 0.0243 0.0632 0.1309
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0074 0.0135 0.0216
Echinococcus granulosus survival motor neuron protein 1 0.0258 0.0674 0.1396
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0456 0.1257 0.2086
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0073 0.0033
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0074 0.0135 0.0271
Loa Loa (eye worm) hypothetical protein 0.02 0.0505 0.0835

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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