Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4711 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.4252 | 0.4252 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0101 | 0.4711 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.4252 | 0.4252 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0093 | 0.4252 | 0.52 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0101 | 0.4711 | 0.4711 |
Giardia lamblia | Kinase, PLK | 0.0101 | 0.4711 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0101 | 0.4711 | 0.4711 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0101 | 0.4711 | 1 |
Schistosoma mansoni | kinase | 0.0051 | 0.178 | 0.178 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0101 | 0.4711 | 0.5762 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0101 | 0.4711 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0093 | 0.4252 | 0.52 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.4252 | 0.4252 |
Trichomonas vaginalis | CAMK family protein kinase | 0.005 | 0.1702 | 0.3612 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0101 | 0.4711 | 1 |
Brugia malayi | Muscleblind-like protein | 0.016 | 0.8176 | 1 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0101 | 0.4711 | 0.5762 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.4252 | 0.4252 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4711 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4711 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0101 | 0.4711 | 0.4711 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.4252 | 0.4252 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.4252 | 0.4252 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4711 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.4252 | 0.4252 |
Echinococcus multilocularis | muscleblind protein | 0.016 | 0.8176 | 0.8176 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4711 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0101 | 0.4711 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.005 | 0.1702 | 0.3612 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.8176 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.016 | 0.8176 | 0.8176 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4711 | 1 |
Trypanosoma brucei | polo-like protein kinase | 0.0101 | 0.4711 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0101 | 0.4711 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.8176 | 1 |
Echinococcus granulosus | muscleblind protein | 0.016 | 0.8176 | 0.8176 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.