Detailed information for compound 1182197

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1479.7 | Formula: C72H87FN18O12S2
  • H donors: 12 H acceptors: 13 LogP: 1.02 Rotable bonds: 36
    Rule of 5 violations (Lipinski): 4
  • SMILES: O=C(Nc1cn(c(c1)C(=O)Nc1cn(c(c1)C(=O)Nc1cn(c(c1)C(=O)Nc1cn(c(c1)C(=O)NCCNC(=S)NCCSCC(=O)[C@]1(O)[C@@H](C)C[C@H]2[C@@]1(C)C[C@@H](O)[C@@]1([C@@H]2CCC2=CC(=O)C=C[C@@]12C)F)C)C)C)C)CCCNC(=O)c1cc(cn1C)NC(=O)c1cc(cn1C)NC(=O)c1nccn1C
  • InChi: 1S/C72H87FN18O12S2/c1-40-24-50-49-14-13-41-25-48(92)15-16-69(41,2)71(49,73)57(93)32-70(50,3)72(40,103)58(94)39-105-23-21-78-68(104)77-19-18-76-62(97)52-28-44(35-87(52)6)81-64(99)54-30-46(37-89(54)8)83-65(100)55-29-45(36-90(55)9)82-63(98)53-26-42(33-88(53)7)79-59(95)12-11-17-75-61(96)51-27-43(34-86(51)5)80-66(101)56-31-47(38-91(56)10)84-67(102)60-74-20-22-85(60)4/h15-16,20,22,25-31,33-38,40,49-50,57,93,103H,11-14,17-19,21,23-24,32,39H2,1-10H3,(H,75,96)(H,76,97)(H,79,95)(H,80,101)(H,81,99)(H,82,98)(H,83,100)(H,84,102)(H2,77,78,104)/t40-,49+,50+,57+,69+,70+,71+,72+/m0/s1
  • InChiKey: VWZBYQWNWNDGBB-VLAXSKAVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis replication factor c subunit 1 0.002 0.0002 0.0002
Echinococcus granulosus neuropeptide receptor 0.0051 0.0097 0.0134
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0051 0.0097 0.0097
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0022 0.0009 0.0028
Mycobacterium tuberculosis Probable lipase LipD 0.0196 0.0531 0.0863
Plasmodium falciparum pyruvate kinase 2 0.002 0.0003 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0074 0.0237
Schistosoma mansoni nuclear receptor nhr-48 0.0048 0.0087 0.012
Entamoeba histolytica pyruvate kinase, putative 0.0027 0.0024 0.0034
Onchocerca volvulus 0.0035 0.0048 0.0536
Loa Loa (eye worm) hypothetical protein 0.0019 0.0001 0.0002
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0024 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0048 0.0067
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0032 0.0039 0.0054
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0144
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0102 0.0248 0.0343
Giardia lamblia Isoprenylcysteine carboxyl methyltransferase 0.2426 0.7216 1
Schistosoma mansoni chromosome transmission fidelity factor 0.002 0.0002 0.0003
Echinococcus multilocularis lamin 0.003 0.0033 0.0033
Echinococcus multilocularis somatostatin receptor 0.0051 0.0097 0.0097
Echinococcus granulosus survival motor neuron protein 1 0.0473 0.136 0.1884
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0028 0.0038
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0097 0.0097
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0102 0.0248 0.0343
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0074 0.0237
Brugia malayi CHE-14 protein 0.0084 0.0196 0.0272
Echinococcus granulosus microtubule associated protein 2 0.2058 0.6113 0.8472
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0111 0.0276 0.0382
Loa Loa (eye worm) hypothetical protein 0.0106 0.0259 0.0359
Echinococcus granulosus expressed conserved protein 0.0185 0.0497 0.0689
Leishmania major cathepsin L-like protease 0.0134 0.0344 0.0476
Onchocerca volvulus Matrix metalloproteinase homolog 0.0202 0.055 0.6175
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0102 0.0248 0.0248
Echinococcus multilocularis cpg binding protein 0.0191 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0102 0.0248 0.0343
Schistosoma mansoni myosin xvIII 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0087 0.012
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0048 0.0087 0.097
Mycobacterium tuberculosis Probable hydrolase 0.0196 0.0531 0.0863
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0197 0.0533 0.0738
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0048 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0048 0.0067
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0096 0.0232 0.0321
Brugia malayi Cathepsin L-like precursor 0.0023 0.0013 0.0019
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0114 0.0285 0.0285
Mycobacterium ulcerans recombinase A 0.0126 0.032 0.1028
Echinococcus multilocularis netrin receptor unc 5 0.0032 0.0039 0.0039
Entamoeba histolytica hypothetical protein 0.0106 0.0261 0.0362
Schistosoma mansoni lamin 0.003 0.0033 0.0046
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0097 0.0097
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0038 0.0056 0.009
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0071 0.0155 0.0155
Loa Loa (eye worm) hypothetical protein 0.004 0.0063 0.0087
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0044 0.0074 0.0074
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0097 0.0097
Schistosoma mansoni opsin-like receptor 0.0051 0.0097 0.0134
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0074 0.012
Brugia malayi hypothetical protein 0.0051 0.0097 0.0134
Brugia malayi Cathepsin L-like precursor 0.0035 0.0048 0.0067
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0332 0.0938 0.0938
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0146 0.0202
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Onchocerca volvulus Matrilysin homolog 0.0091 0.0217 0.2429
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0045 0.0078 0.0078
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0102 0.0248 0.0343
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0111 0.0276 0.0383
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0051 0.0097 0.0134
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0101 0.0247 0.0342
Mycobacterium ulcerans hypothetical protein 0.0157 0.0413 0.1325
Brugia malayi hypothetical protein 0.0051 0.0097 0.0134
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0106 0.0261 0.0362
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Mycobacterium ulcerans hypothetical protein 0.0149 0.0388 0.1246
Echinococcus multilocularis pyruvate kinase 0.002 0.0003 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.0149 0.0388 0.1246
Schistosoma mansoni pyruvate kinase 0.0039 0.006 0.0083
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0044 0.0074 0.0102
Echinococcus multilocularis neuropeptide s receptor 0.1013 0.2981 0.2981
Loa Loa (eye worm) hypothetical protein 0.0028 0.0028 0.0038
Loa Loa (eye worm) cysteine protease 0.0035 0.0048 0.0067
Schistosoma mansoni lamin 0.003 0.0033 0.0046
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0196 0.0531 0.0863
Trichomonas vaginalis maltase-glucoamylase, putative 0.0028 0.0028 0.0038
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0101 0.0247 0.0342
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0097 0.0134
Echinococcus granulosus geminin 0.0338 0.0957 0.1326
Echinococcus granulosus neuropeptide receptor 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0103 0.0253 0.0351
Echinococcus granulosus g protein coupled receptor 0.0051 0.0097 0.0134
Schistosoma mansoni topbp1 0.002 0.0002 0.0003
Onchocerca volvulus 0.0051 0.0097 0.1085
Echinococcus granulosus nibrin 0.002 0.0002 0.0003
Trypanosoma brucei protein kinase, putative 0.005 0.0092 0.0127
Brugia malayi Nuclear hormone receptor-like 1 0.0102 0.0248 0.0343
Brugia malayi nuclear hormone receptor family member nhr-6 0.0048 0.0087 0.012
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0366 0.0507
Brugia malayi Muscleblind-like protein 0.0174 0.0466 0.0645
Schistosoma mansoni amine GPCR 0.0051 0.0097 0.0134
Brugia malayi Cathepsin L-like precursor 0.0035 0.0048 0.0067
Loa Loa (eye worm) hypothetical protein 0.0316 0.089 0.1234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0013 0.0019
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0068 0.0095
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0026 0.0022 0.0031
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0063 0.0087
Brugia malayi Glycosyl hydrolases family 31 protein 0.0028 0.0028 0.0038
Schistosoma mansoni DNA ligase IV 0.002 0.0002 0.0003
Loa Loa (eye worm) beta-lactamase 0.0196 0.0531 0.0736
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0102 0.0248 0.0343
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0101 0.0247 0.0342
Loa Loa (eye worm) hypothetical protein 0.0089 0.021 0.0292
Brugia malayi Latrophilin receptor protein 2 0.0114 0.0285 0.0395
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0051 0.0097 0.0097
Echinococcus multilocularis dna polymerase eta 0.0044 0.0075 0.0075
Toxoplasma gondii pyruvate kinase PyKII 0.002 0.0003 0.0001
Mycobacterium ulcerans esterase/lipase LipP 0.0196 0.0531 0.1704
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0102 0.0248 0.0343
Echinococcus multilocularis Niemann Pick C1 protein 0.0197 0.0533 0.0533
Onchocerca volvulus 0.0051 0.0097 0.1085
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0043 0.006
Loa Loa (eye worm) hypothetical protein 0.0102 0.0248 0.0343
Entamoeba histolytica cysteine protease, putative 0.0035 0.0048 0.0067
Loa Loa (eye worm) hypothetical protein 0.0044 0.0075 0.0104
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0342 0.0969 0.1343
Brugia malayi beta-lactamase family protein 0.0196 0.0531 0.0736
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0063 0.0087
Trichomonas vaginalis D-aminoacylase, putative 0.0196 0.0531 0.0736
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0044 0.0074 0.012
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0044 0.0074 0.0333
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0028 0.0028 0.0307
Echinococcus granulosus FTZ F1 alpha 0.0102 0.0248 0.0343
Onchocerca volvulus Cathepsin F homolog 0.0035 0.0048 0.0536
Loa Loa (eye worm) CXXC zinc finger family protein 0.0176 0.0472 0.0654
Loa Loa (eye worm) melatonin receptor type 1A 0.0051 0.0097 0.0134
Onchocerca volvulus 0.0051 0.0097 0.1085
Onchocerca volvulus 0.0051 0.0097 0.1085
Echinococcus granulosus g protein coupled receptor 0.0051 0.0097 0.0134
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0097 0.0134
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0051 0.0097 0.0134
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0074 0.0102
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0074 0.0237
Onchocerca volvulus 0.0196 0.0531 0.5966
Echinococcus multilocularis serotonin receptor 0.0051 0.0097 0.0097
Echinococcus granulosus mixed lineage leukemia protein mll 0.0045 0.0078 0.0108
Echinococcus multilocularis G-protein coupled receptor, putative 0.0051 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Echinococcus granulosus dro:myosuppressin receptor 0.0051 0.0097 0.0134
Mycobacterium tuberculosis Conserved hypothetical protein 0.0157 0.0413 0.0671
Schistosoma mansoni biogenic amine receptor 0.0051 0.0097 0.0134
Brugia malayi G protein-coupled receptor 0.0051 0.0097 0.0134
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0051 0.0097 0.0134
Echinococcus granulosus dnaJ subfamily B 0.2072 0.6154 0.8529
Brugia malayi hypothetical protein 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0084 0.0195 0.027
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0097 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0102 0.0248 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0027 0.0024 0.0033
Brugia malayi Nuclear hormone receptor E75 0.0048 0.0087 0.012
Plasmodium falciparum acyl-CoA synthetase 0.0111 0.0276 0.038
Onchocerca volvulus 0.0316 0.089 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0028 0.0038
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0076 0.0171 0.0237
Trypanosoma brucei glycosyl hydrolase-like protein 0.0028 0.0028 0.0038
Echinococcus multilocularis neuropeptide Y receptor 0.0051 0.0097 0.0097
Schistosoma mansoni protein-s-isoprenylcysteine o-methyltransferase 0.2426 0.7216 1
Schistosoma mansoni biogenic amine receptor 0.0051 0.0097 0.0134
Onchocerca volvulus Protein ultraspiracle homolog 0.0102 0.0248 0.278
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0051 0.0097 0.0097
Schistosoma mansoni hypothetical protein 0.0338 0.0957 0.1326
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0092 0.0127
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0101 0.0247 0.0342
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0097 0.0134
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0074 0.0237
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0068 0.0095
Onchocerca volvulus 0.0051 0.0097 0.1085
Brugia malayi exodeoxyribonuclease III family protein 0.0022 0.0009 0.0012
Echinococcus multilocularis protein patched 0.0084 0.0196 0.0196
Echinococcus granulosus neuropeptide s receptor 0.1013 0.2981 0.4131
Onchocerca volvulus 0.0051 0.0097 0.1085
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0102 0.0248 0.0343
Brugia malayi G-protein coupled receptor 0.0051 0.0097 0.0134
Echinococcus multilocularis orexin receptor type 2 0.0051 0.0097 0.0097
Loa Loa (eye worm) pyruvate kinase 0.0039 0.006 0.0083
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0048 0.0536
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0025 0.0017 0.0024
Schistosoma mansoni alpha-1 adrenergic receptor 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Trichomonas vaginalis hypothetical protein 0.0021 0.0007 0.001
Brugia malayi Matrixin family protein 0.0091 0.0217 0.03
Giardia lamblia Pyruvate kinase 0.002 0.0003 0.0004
Echinococcus granulosus tumor protein p63 0.0721 0.2104 0.2917
Loa Loa (eye worm) steroid hormone receptor 0.0102 0.0248 0.0343
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0196 0.0531 0.0863
Schistosoma mansoni nuclear receptor 0.0048 0.0087 0.012
Plasmodium vivax acyl-CoA synthetase, putative 0.0111 0.0276 0.038
Brugia malayi Dopamine receptor protein 1 0.0051 0.0097 0.0134
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0051 0.0097 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0063 0.0087
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0092 0.0127
Brugia malayi sulfakinin receptor protein 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0174 0.0466 0.0645
Loa Loa (eye worm) hypothetical protein 0.0111 0.0276 0.0382
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0075 0.0104
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0092 0.0127
Brugia malayi RE15519p 0.0051 0.0097 0.0134
Leishmania major 4-coumarate:coa ligase-like protein 0.0149 0.0388 0.0538
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Chlamydia trachomatis pyruvate kinase 0.0039 0.006 0.1812
Echinococcus multilocularis zinc finger protein 0.0053 0.0102 0.0102
Schistosoma mansoni netrin receptor unc5 0.0032 0.0039 0.0054
Echinococcus granulosus fetal alzheimer antigen falz 0.0059 0.0121 0.0168
Mycobacterium ulcerans hydrolase 0.0111 0.0276 0.0886
Brugia malayi ecdysone receptor 0.0048 0.0087 0.012
Onchocerca volvulus 0.0035 0.0048 0.0536
Chlamydia trachomatis recombinase RecA 0.0126 0.032 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0022 0.0009 0.0012
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0039 0.0059 0.0082
Echinococcus granulosus thyroid hormone receptor alpha 0.0048 0.0087 0.012
Loa Loa (eye worm) hypothetical protein 0.0071 0.0155 0.0215
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0079 0.0179 0.0179
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0092 0.0127
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0024 0.0033
Onchocerca volvulus 0.0149 0.0388 0.4361
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0051 0.0097 0.0134
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0102 0.0248 0.0343
Echinococcus granulosus G protein coupled receptor 139 0.0051 0.0097 0.0134
Brugia malayi Pre-SET motif family protein 0.0033 0.0043 0.006
Schistosoma mansoni hypothetical protein 0.0081 0.0187 0.0259
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0126 0.032 0.1478
Brugia malayi orphan nuclear receptor NR2E1 0.0048 0.0087 0.012
Leishmania major cathepsin L-like protease 0.0035 0.0048 0.0067
Schistosoma mansoni intermediate filament proteins 0.003 0.0033 0.0046
Leishmania major pyruvate kinase 0.0039 0.006 0.0083
Loa Loa (eye worm) hypothetical protein 0.0027 0.0024 0.0034
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0096 0.0133
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0104 0.0144
Schistosoma mansoni glutaminase 0.0298 0.0838 0.1161
Brugia malayi AMP-binding enzyme family protein 0.0149 0.0388 0.0538
Brugia malayi Matrixin family protein 0.0091 0.0217 0.03
Loa Loa (eye worm) hypothetical protein 0.0196 0.0531 0.0736
Echinococcus multilocularis neuropeptide receptor A26 0.1013 0.2981 0.2981
Trichomonas vaginalis penicillin-binding protein, putative 0.0196 0.0531 0.0736
Trypanosoma cruzi hypothetical protein, conserved 0.0196 0.0531 0.0736
Entamoeba histolytica hypothetical protein 0.002 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.0114 0.0285 0.0395
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0258 0.0419
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0258 0.0419
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0048 0.0067
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0102 0.0248 0.0248
Brugia malayi hypothetical protein 0.0048 0.0087 0.012
Brugia malayi Pyruvate kinase, M2 isozyme 0.0039 0.006 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0002 0.0003
Mycobacterium tuberculosis Conserved hypothetical membrane protein 0.1059 0.3118 0.5065
Loa Loa (eye worm) hypothetical protein 0.0196 0.0531 0.0736
Echinococcus multilocularis pyruvate kinase 0.002 0.0003 0.0003
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0097 0.0097
Echinococcus granulosus allatostatin A receptor 0.0051 0.0097 0.0134
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0092 0.0127
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0044 0.0074 0.0102
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0054 0.0104 0.0144
Schistosoma mansoni biogenic amine receptor 0.0051 0.0097 0.0134
Schistosoma mansoni nuclear hormone receptor 0.0102 0.0248 0.0343
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0044 0.0074 0.0237
Onchocerca volvulus 0.0051 0.0097 0.1085
Leishmania major mitochondrial DNA polymerase beta 0.0298 0.0836 0.1158
Schistosoma mansoni neuropeptide receptor 0.0051 0.0097 0.0134
Schistosoma mansoni retinoic acid receptor RXR 0.0102 0.0248 0.0343
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.006 0.0665
Echinococcus granulosus zinc finger protein 0.0053 0.0102 0.0141
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0017 0.0022
Brugia malayi hypothetical protein 0.0051 0.0097 0.0134
Echinococcus granulosus dna polymerase eta 0.0044 0.0075 0.0104
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0054 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.2073 0.6156 1
Echinococcus granulosus lamin 0.003 0.0033 0.0046
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0028 0.0038
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0092 0.0127
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0051 0.0097 0.1085
Loa Loa (eye worm) hypothetical protein 0.0196 0.0531 0.0736
Echinococcus granulosus fmrfamide receptor 0.0051 0.0097 0.0134
Schistosoma mansoni hypothetical protein 0.0081 0.0187 0.0259
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0097 0.0097
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0048 0.0067
Schistosoma mansoni hypothetical protein 0.2072 0.6154 0.8529
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0102 0.0248 0.0343
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0048 0.0087 0.0087
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0074 0.0102
Trypanosoma cruzi FHA domain containing protein, putative 0.002 0.0002 0.0003
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0097 0.0134
Echinococcus multilocularis pyruvate kinase 0.0039 0.006 0.006
Echinococcus multilocularis protein dispatched 1 0.0096 0.0232 0.0232
Echinococcus multilocularis musashi 0.003 0.0033 0.0033
Brugia malayi MH2 domain containing protein 0.0251 0.0695 0.0963
Brugia malayi Cathepsin L-like cysteine proteinase 0.0023 0.0013 0.0019
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Brugia malayi Melibiase family protein 0.0068 0.0146 0.0202
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0092 0.0127
Trypanosoma brucei prenyl protein specific carboxyl methyltransferase 0.2426 0.7216 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0097 0.0097
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0196 0.0531 0.0736
Schistosoma mansoni cathepsin F (C01 family) 0.0035 0.0048 0.0067
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0051 0.0097 0.0134
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0141 0.0365 0.0365
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0045 0.0078 0.0078
Treponema pallidum exodeoxyribonuclease (exoA) 0.0022 0.0009 0.0214
Loa Loa (eye worm) glutaminase 2 0.0298 0.0838 0.1161
Brugia malayi Cathepsin L-like precursor 0.0035 0.0048 0.0067
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0171 0.0237
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0102 0.0248 0.0343
Echinococcus granulosus sex peptide receptor 0.0051 0.0097 0.0134
Schistosoma mansoni nuclear receptor 0.0048 0.0087 0.012
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0102 0.0248 0.278
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0092 0.0127
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0051 0.0097 0.0134
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0028 0.0038
Loa Loa (eye worm) hypothetical protein 0.0126 0.032 0.0444
Brugia malayi Glycosyl hydrolases family 31 protein 0.0076 0.0171 0.0237
Schistosoma mansoni RAR-like nuclear receptor 0.0102 0.0248 0.0343
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0344 0.0476
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0097 0.0097
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0102 0.0248 0.0343
Onchocerca volvulus 0.003 0.0033 0.0364
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0149 0.0388 0.1246
Brugia malayi ecdysteroid receptor 0.0102 0.0248 0.0343
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0097 0.0134
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0044 0.0074 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0063 0.0087
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0048 0.0087 0.0087
Echinococcus granulosus Nuclear hormone receptor HR96 0.0048 0.0087 0.012
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0171 0.0237
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Echinococcus granulosus neuropeptides capa receptor 0.0051 0.0097 0.0134
Echinococcus granulosus protein S isoprenylcysteine O methyltransferase 0.2426 0.7216 1
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0027 0.0024 0.0033
Trichomonas vaginalis D-aminoacylase, putative 0.0196 0.0531 0.0736
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0276 0.077 0.1067
Schistosoma mansoni neuropeptide f receptor 76f 0.0051 0.0097 0.0134
Brugia malayi photoreceptor-specific nuclear receptor 0.0102 0.0248 0.0343
Brugia malayi hypothetical protein 0.0054 0.0104 0.0144
Leishmania major 4-coumarate:coa ligase-like protein 0.0149 0.0388 0.0538
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Leishmania major cathepsin L-like protease 0.0134 0.0344 0.0476
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0196 0.0531 0.0863
Echinococcus granulosus peptide allatostatin:somatostatin 0.0051 0.0097 0.0134
Echinococcus granulosus hypothetical protein 0.0051 0.0097 0.0134
Trypanosoma cruzi DNA repair protein, putative 0.0039 0.0059 0.0082
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.004 0.0063 0.0085
Brugia malayi Hemopexin family protein 0.0129 0.0331 0.0459
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0063 0.0087
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0068 0.0146 0.0202
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0258 0.0419
Brugia malayi Matrixin family protein 0.0221 0.0605 0.0838
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0092 0.0092
Onchocerca volvulus 0.0051 0.0097 0.1085
Brugia malayi hypothetical protein 0.0106 0.0261 0.0362
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0097 0.0134
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0027 0.0024 0.0033
Echinococcus multilocularis Ankyrin 0.0032 0.0039 0.0039
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0074 0.0237
Schistosoma mansoni hypothetical protein 0.0114 0.0285 0.0395
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0044 0.0074 0.012
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0102 0.0248 0.0248
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0102 0.0248 0.0343
Brugia malayi nuclear hormone receptor family member odr-7 0.0048 0.0087 0.012
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0076 0.0171 0.0234
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0111 0.0276 0.0449
Schistosoma mansoni DNA polymerase eta 0.0044 0.0075 0.0104
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0171 0.0237
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0375 0.1068 0.1481
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0155 0.0407 0.0564
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0048 0.0067
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0092 0.0127
Leishmania major acetyl-CoA synthetase, putative 0.0044 0.0074 0.0102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0097 0.0134
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0051 0.0097 0.0097
Mycobacterium tuberculosis Conserved protein 0.0196 0.0531 0.0863
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0063 0.0087
Schistosoma mansoni ankyrin 23/unc44 0.0032 0.0039 0.0054
Echinococcus granulosus histone lysine methyltransferase setb 0.0071 0.0155 0.0215
Schistosoma mansoni cpg binding protein 0.0176 0.0472 0.0654
Brugia malayi Immunoglobulin I-set domain containing protein 0.0032 0.0039 0.0054
Echinococcus multilocularis 0.2426 0.7216 0.7216
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0344 0.0476
Onchocerca volvulus 0.002 0.0002 0.0017
Loa Loa (eye worm) histone methyltransferase 0.0056 0.011 0.0152
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0044 0.0074 0.0237
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Trichomonas vaginalis pyruvate kinase, putative 0.0039 0.006 0.0083
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0092 0.0125
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0054 0.0104 0.0144
Mycobacterium tuberculosis Probable esterase LipL 0.0196 0.0531 0.0863
Brugia malayi conserved hypotetical protein 0.0048 0.0087 0.012
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0097 0.0134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0344 0.0476
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0074 0.0102
Echinococcus multilocularis dro:myosuppressin receptor 0.0051 0.0097 0.0097
Schistosoma mansoni amine GPCR 0.0051 0.0097 0.0134
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.006 0.0665
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0102 0.0248 0.0343
Loa Loa (eye worm) glutaminase 0.0298 0.0838 0.1161
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0032 0.0039 0.0054
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0051 0.0097 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0102 0.0248 0.0343
Mycobacterium ulcerans pyruvate kinase 0.0039 0.006 0.0191
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0097 0.0134
Plasmodium vivax hypothetical protein, conserved 0.0196 0.0531 0.0734
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0074 0.0237
Brugia malayi Cathepsin L-like precursor 0.0035 0.0048 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0102 0.0248 0.0343
Echinococcus granulosus Nuclear hormone receptor HR96 0.0048 0.0087 0.012
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0022 0.0009 0.0014
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0036 0.005
Schistosoma mansoni opsin-like receptor 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0126 0.032 0.0444
Loa Loa (eye worm) hypothetical protein 0.0473 0.136 0.1884
Echinococcus multilocularis pyruvate kinase 0.0031 0.0035 0.0035
Toxoplasma gondii ATPase, AAA family protein 0.002 0.0002 0.00000047797
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0051 0.0097 0.0134
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0033 0.0046
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0091 0.0217 0.03
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.2426 0.7216 1
Brugia malayi ORL1-like opioid receptor 0.0051 0.0097 0.0134
Echinococcus granulosus Ankyrin 0.0032 0.0039 0.0054
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0097 0.0134
Loa Loa (eye worm) TYRA-2 protein 0.0051 0.0097 0.0134
Mycobacterium ulcerans lipase LipD 0.0196 0.0531 0.1704
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0009 0.0009
Echinococcus granulosus cathepsin l1 0.0035 0.0048 0.0067
Trypanosoma cruzi major cysteine proteinase, putative 0.0105 0.0258 0.0358
Entamoeba histolytica hypothetical protein 0.0106 0.0261 0.0362
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0043 0.0057
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0022 0.0009 0.0009
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0344 0.0476
Echinococcus multilocularis lysosomal alpha glucosidase 0.0342 0.0969 0.0969
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0002 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0102 0.0248 0.0343
Loa Loa (eye worm) oxidoreductase 0.0044 0.0074 0.0102
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Echinococcus granulosus tachykinin peptides receptor 99D 0.0051 0.0097 0.0134
Onchocerca volvulus 0.0044 0.0074 0.0824
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0044 0.0074 0.012
Loa Loa (eye worm) hypothetical protein 0.0084 0.0196 0.0272
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0344 0.0476
Loa Loa (eye worm) hypothetical protein 0.0149 0.0388 0.0538
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0097 0.0134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0097 0.0134
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0102 0.0248 0.0248
Echinococcus multilocularis sex peptide receptor 0.0051 0.0097 0.0097
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0051 0.0097 0.0097
Brugia malayi Cathepsin L-like precursor 0.0035 0.0048 0.0067
Leishmania major hypothetical protein, conserved 0.0025 0.0017 0.0024
Echinococcus granulosus death domain containing protein 0.0032 0.0039 0.0054
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0039 0.006 0.0097
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0009 0.0012
Toxoplasma gondii ABC1 family protein 0.0196 0.0531 0.0734
Loa Loa (eye worm) pyruvate kinase-PB 0.0027 0.0024 0.0034
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0051 0.0097 0.0134
Schistosoma mansoni zinc finger protein 0.0033 0.0043 0.006
Schistosoma mansoni hypothetical protein 0.0096 0.0232 0.0321
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0102 0.0248 0.0343
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0097 0.0134
Brugia malayi hypothetical protein 0.0025 0.0017 0.0024
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0027 0.0024 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Echinococcus granulosus ecdysone induced protein 78C 0.0102 0.0248 0.0343
Schistosoma mansoni neuropeptide F-like receptor 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0111 0.0276 0.0382
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0051 0.0097 0.0134
Schistosoma mansoni acetyl-CoA synthetase 0.0044 0.0074 0.0102
Loa Loa (eye worm) hypothetical protein 0.0111 0.0276 0.0382
Loa Loa (eye worm) hypothetical protein 0.0247 0.0682 0.0945
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0048 0.0087 0.012
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0027 0.0024 0.0033
Plasmodium falciparum pyruvate kinase 0.0039 0.006 0.008
Schistosoma mansoni transcription factor LCR-F1 0.0106 0.0261 0.0362
Schistosoma mansoni hypothetical protein 0.0045 0.0078 0.0109
Brugia malayi Calcitonin receptor-like protein seb-1 0.0361 0.1024 0.142
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0298 0.0836 0.1158
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0076 0.0171 0.0237
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Trypanosoma cruzi cysteine peptidase, putative 0.0134 0.0344 0.0476
Schistosoma mansoni hypothetical protein 0.0114 0.0285 0.0395
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0102 0.0248 0.0343
Brugia malayi Pre-SET motif family protein 0.021 0.0573 0.0794
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0017 0.0024
Plasmodium vivax vivapain-2 0.0035 0.0048 0.0064
Onchocerca volvulus 0.0044 0.0074 0.0824
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0051 0.0097 0.0134
Echinococcus granulosus cpg binding protein 0.0191 0.0515 0.0713
Brugia malayi hypothetical protein 0.002 0.0002 0.0003
Brugia malayi hypothetical protein 0.002 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0054
Brugia malayi Bromodomain containing protein 0.0084 0.0194 0.0269
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0051 0.0097 0.0097
Brugia malayi follicle stimulating hormone receptor 0.0276 0.077 0.1067
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0103 0.0253 0.0351
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0102 0.0248 0.0343
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0097 0.0134
Echinococcus granulosus Niemann Pick C1 protein 0.0197 0.0533 0.0738
Brugia malayi Pyruvate kinase, muscle isozyme 0.0039 0.006 0.0083
Brugia malayi F/Y-rich N-terminus family protein 0.0059 0.012 0.0167
Echinococcus granulosus muscleblind protein 0.0174 0.0466 0.0645
Onchocerca volvulus 0.0176 0.0472 0.5299
Trichomonas vaginalis chaperonin, putative 0.0027 0.0024 0.0033
Brugia malayi Dopamine receptor protein 2 0.0051 0.0097 0.0134
Brugia malayi Bromodomain containing protein 0.0174 0.0465 0.0645
Brugia malayi MAP kinase sur-1 0.005 0.0092 0.0127
Echinococcus granulosus Niemann Pick C1 protein 0.0281 0.0786 0.1089
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0075 0.0104
Entamoeba histolytica prenyl cysteine carboxyl methyltransferase, putative 0.2426 0.7216 1
Trypanosoma brucei pyruvate kinase 1 0.0039 0.006 0.0083
Loa Loa (eye worm) PHD-finger family protein 0.0045 0.0078 0.0109
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0144
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.2426 0.7216 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0092 0.0127
Mycobacterium ulcerans acyl-CoA synthetase 0.0149 0.0388 0.1246
Onchocerca volvulus 0.0047 0.0085 0.0951
Schistosoma mansoni alpha-glucosidase 0.0295 0.0826 0.1145
Brugia malayi protein-S isoprenylcysteine O-methyltransferase, putative 0.2426 0.7216 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0149 0.0388 0.1246
Toxoplasma gondii histone lysine methyltransferase SET1 0.0341 0.0964 0.1334
Echinococcus granulosus methyl CpG binding domain protein 2 0.0037 0.0055 0.0076
Schistosoma mansoni ap endonuclease 0.0022 0.0009 0.0012
Brugia malayi nuclear hormone receptor 0.0102 0.0248 0.0343
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0149 0.0388 0.1793
Schistosoma mansoni hypothetical protein 0.0032 0.0039 0.0054
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0149 0.0388 0.0631
Brugia malayi AKH receptor 0.0051 0.0097 0.0134
Brugia malayi hypothetical protein 0.0051 0.0097 0.0134
Leishmania major 4-coumarate:coa ligase-like protein 0.0149 0.0388 0.0538
Schistosoma mansoni hypothetical protein 0.0129 0.0331 0.0459
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0171 0.0237
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Trichomonas vaginalis esterase, putative 0.0196 0.0531 0.0736
Echinococcus multilocularis neuropeptide receptor 0.0051 0.0097 0.0097
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0313 0.0881 0.0881
Loa Loa (eye worm) hypothetical protein 0.0044 0.0074 0.0102
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.0104 0.0144
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0048 0.0067
Loa Loa (eye worm) hypothetical protein 0.0196 0.0531 0.0736
Echinococcus multilocularis allatostatin A receptor 0.0051 0.0097 0.0097
Echinococcus multilocularis sterol regulatory element binding protein 0.0084 0.0196 0.0196
Mycobacterium ulcerans glutaminase 0.0298 0.0838 0.2687
Brugia malayi Cathepsin L-like precursor 0.0023 0.0013 0.0019
Schistosoma mansoni bromodomain containing protein 0.0149 0.0388 0.0538
Brugia malayi hypothetical protein 0.0051 0.0097 0.0134
Brugia malayi Tachykinin-like peptides receptor 99D 0.0051 0.0097 0.0134
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1254 0.3702 0.6013
Schistosoma mansoni histamine h1 receptor 0.0051 0.0097 0.0134
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0051 0.0097 0.0097
Onchocerca volvulus 0.0035 0.0048 0.0536
Loa Loa (eye worm) hypothetical protein 0.003 0.0033 0.0046
Mycobacterium leprae Conserved hypothetical protein 0.0739 0.2157 1
Brugia malayi neuropeptide F receptor 0.0051 0.0097 0.0134
Schistosoma mansoni thyroid hormone receptor 0.0102 0.0248 0.0343
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0092 0.0127
Mycobacterium ulcerans beta-lactamase 0.0196 0.0531 0.1704
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0102 0.0248 0.0343
Onchocerca volvulus 0.0051 0.0097 0.1085
Echinococcus granulosus 7tm_1 domain containing protein 0.0051 0.0097 0.0134
Echinococcus granulosus GPCR family 2 0.0114 0.0285 0.0395
Plasmodium falciparum protein-S-isoprenylcysteine O-methyltransferase, putative 0.2426 0.7216 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0344 0.0476
Schistosoma mansoni alpha glucosidase 0.0076 0.0171 0.0237
Echinococcus granulosus neuropeptide FF receptor 2 0.0051 0.0097 0.0134
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0114 0.0285 0.0285
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0102 0.0248 0.0343
Echinococcus multilocularis cysteine protease 0.0035 0.0048 0.0048
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0048 0.0087 0.012
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0035 0.0048 0.0064
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0196 0.0531 0.0736
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Leishmania major hypothetical protein, conserved 0.0196 0.0531 0.0736
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0102 0.0248 0.0343
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Echinococcus multilocularis pyruvate kinase 0.002 0.0003 0.0003
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0037 0.0055 0.0055
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0068 0.0095
Toxoplasma gondii propionate-CoA ligase 0.0044 0.0074 0.01
Loa Loa (eye worm) hypothetical protein 0.0102 0.0248 0.0343
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0076 0.0171 0.0237
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.006 0.0665
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0149 0.0388 0.1246
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0344 0.0476
Brugia malayi Melatonin receptor type 1A 0.0051 0.0097 0.0134
Schistosoma mansoni methyl-cpg binding protein mbd 0.0037 0.0055 0.0076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0048 0.0067
Brugia malayi AMP-binding enzyme family protein 0.0044 0.0074 0.0102
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0028 0.0038
Schistosoma mansoni hypothetical protein 0.0114 0.0285 0.0395
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0074 0.0237
Schistosoma mansoni nuclear hormone receptor 0.0048 0.0087 0.012
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0102 0.0248 0.0343
Brugia malayi hypothetical protein 0.0051 0.0097 0.0134
Onchocerca volvulus 0.0096 0.0232 0.2601
Schistosoma mansoni methyl-cpg binding protein mbd 0.0037 0.0055 0.0076
Plasmodium falciparum T-complex protein 1 subunit beta 0.0027 0.0024 0.003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0019
Onchocerca volvulus 0.0129 0.0331 0.3714
Brugia malayi hypothetical protein 0.0316 0.089 0.1234
Brugia malayi topoisomerase 0.002 0.0002 0.0003
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0044 0.0074 0.01
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0063 0.0087
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0044 0.0074 0.012
Echinococcus granulosus somatostatin receptor 0.0051 0.0097 0.0134
Brugia malayi intermediate filament protein 0.003 0.0033 0.0046
Brugia malayi larval opioid receptor 0.0051 0.0097 0.0134
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Mycobacterium tuberculosis Conserved protein 0.0196 0.0531 0.0863
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Echinococcus multilocularis neutral alpha glucosidase AB 0.0076 0.0171 0.0171
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0043 0.0043
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0196 0.0531 0.0736
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0051 0.0097 0.0134
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0097 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0002 0.0003
Brugia malayi tailless protein 0.0048 0.0087 0.012
Echinococcus granulosus neuropeptide Y receptor 0.0051 0.0097 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0102 0.0248 0.0343
Loa Loa (eye worm) hypothetical protein 0.0102 0.0248 0.0343
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0122 0.0309 0.0428
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0102 0.0248 0.0343
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0002 0.0003
Onchocerca volvulus 0.0048 0.0087 0.097
Trichomonas vaginalis antibiotic synthetase, putative 0.0044 0.0074 0.0102
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Schistosoma mansoni amine GPCR 0.0051 0.0097 0.0134
Plasmodium vivax protein-S-isoprenylcysteine O-methyltransferase, putative 0.2426 0.7216 1
Echinococcus multilocularis expressed conserved protein 0.0185 0.0497 0.0497
Schistosoma mansoni ap endonuclease 0.0022 0.0009 0.0012
Schistosoma mansoni coup transcription factor 0.0102 0.0248 0.0343
Brugia malayi putative neuropeptide receptor 0.0051 0.0097 0.0134
Schistosoma mansoni thyroid hormone receptor 0.0102 0.0248 0.0343
Echinococcus granulosus intermediate filament protein 0.003 0.0033 0.0046
Entamoeba histolytica acyl-coA synthetase, putative 0.0149 0.0388 0.0538
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0071 0.0155 0.0215
Plasmodium falciparum cysteine proteinase falcipain 3 0.0035 0.0048 0.0064
Echinococcus multilocularis Niemann Pick C1 protein 0.0281 0.0786 0.0786
Treponema pallidum recombinase A 0.0126 0.032 1
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0075 0.0104
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0361 0.1024 0.142
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0063 0.0087
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0002 0.0003
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0044 0.0074 0.012
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0002 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0035 0.0048 0.0067
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0044 0.0074 0.0102
Onchocerca volvulus 0.0106 0.0259 0.2909
Loa Loa (eye worm) hypothetical protein 0.0361 0.1024 0.142
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0044 0.0074 0.01
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Onchocerca volvulus 0.0035 0.0048 0.0536
Echinococcus granulosus lamin dm0 0.003 0.0033 0.0046
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0097 0.0134
Leishmania major cathepsin L-like protease 0.0035 0.0048 0.0067
Toxoplasma gondii pyruvate kinase PyK1 0.0039 0.006 0.008
Loa Loa (eye worm) bromodomain containing protein 0.0039 0.0059 0.0082
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0196 0.0531 0.1704
Leishmania major DNA polymerase eta, putative 0.0031 0.0036 0.005
Mycobacterium tuberculosis Probable lipase LipE 0.0196 0.0531 0.0863
Brugia malayi hypothetical protein 0.0036 0.0051 0.0071
Loa Loa (eye worm) hypothetical protein 0.0035 0.0048 0.0067
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0146 0.0202
Onchocerca volvulus 0.0044 0.0074 0.0824
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0044 0.0074 0.0237
Trypanosoma cruzi ISWI complex protein 0.0033 0.0043 0.006
Echinococcus multilocularis ecdysone induced protein 78C 0.0102 0.0248 0.0248
Echinococcus granulosus pyruvate kinase 0.002 0.0003 0.0004
Trypanosoma brucei ISWI complex protein 0.0033 0.0043 0.006
Loa Loa (eye worm) DR-78 0.0048 0.0087 0.012
Leishmania major acetyl-CoA synthetase, putative 0.0044 0.0074 0.0102
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0044 0.0074 0.0102
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0044 0.0074 0.0237
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0141 0.0366 0.0507
Echinococcus multilocularis microtubule associated protein 2 0.2058 0.6113 0.6113
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0059 0.0121 0.0168
Toxoplasma gondii melibiase subfamily protein 0.0101 0.0247 0.034
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0051 0.0097 0.0134
Schistosoma mansoni cpg binding protein 0.0191 0.0515 0.0713
Echinococcus multilocularis fmrfamide receptor 0.0051 0.0097 0.0097
Schistosoma mansoni adenoreceptor 0.0051 0.0097 0.0134
Trypanosoma cruzi cysteine peptidase, putative 0.0134 0.0344 0.0476
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0063 0.0087
Echinococcus multilocularis serotonin receptor 0.0051 0.0097 0.0097
Brugia malayi Pax transcription activation domain interacting protein 0.002 0.0002 0.0003
Echinococcus granulosus biogenic amine 5HT receptor 0.0051 0.0097 0.0134
Echinococcus multilocularis g-protein coupled receptor 0.0051 0.0097 0.0097
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0048 0.0048
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0105 0.0258 0.0419
Trichomonas vaginalis replication factor C large subunit, putative 0.002 0.0002 0.0003
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0332 0.0938 0.13
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0101 0.0247 0.0247
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0027 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Trypanosoma cruzi prenyl protein specific carboxyl methyltransferase, putative 0.2426 0.7216 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0361 0.1024 0.142
Echinococcus granulosus netrin receptor unc 5 0.0032 0.0039 0.0054
Schistosoma mansoni steroid hormone receptor ad4bp 0.0102 0.0248 0.0343
Echinococcus granulosus 7TM GPCR rhodopsin 0.0051 0.0097 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0196 0.0272
Trichomonas vaginalis antibiotic synthetase, putative 0.0044 0.0074 0.0102
Trypanosoma cruzi cruzipain precursor, putative 0.0134 0.0344 0.0476
Schistosoma mansoni hypothetical protein 0.0106 0.0261 0.0362
Onchocerca volvulus 0.0051 0.0097 0.1085
Echinococcus granulosus alpha 1A adrenergic receptor 0.0051 0.0097 0.0134
Brugia malayi putative neuropeptide receptor NPR1 0.0051 0.0097 0.0134
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0028 0.0038
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0045 0.0078 0.0108
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0028 0.0038
Plasmodium vivax acetyl-CoA synthetase, putative 0.0044 0.0074 0.01
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0097 0.0134
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0048 0.0067
Loa Loa (eye worm) hypothetical protein 0.0196 0.0531 0.0736
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0056 0.011 0.011
Loa Loa (eye worm) T-complex protein 1 0.0027 0.0024 0.0033
Trypanosoma cruzi ISWI complex protein 0.0033 0.0043 0.006
Echinococcus granulosus pyruvate kinase 0.0039 0.006 0.0083
Loa Loa (eye worm) fibroinase 0.0035 0.0048 0.0067
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0114 0.0285 0.0395
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0044 0.0074 0.0237
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0102 0.0248 0.0343
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Mycobacterium ulcerans acetyl-CoA synthetase 0.0044 0.0074 0.0237
Onchocerca volvulus Huntingtin homolog 0.0126 0.032 0.3597
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Schistosoma mansoni pyruvate kinase 0.002 0.0003 0.0004
Trichomonas vaginalis maltase-glucoamylase, putative 0.0076 0.0171 0.0237
Onchocerca volvulus Huntingtin homolog 0.0126 0.032 0.3597
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Loa Loa (eye worm) nuclear receptor NHR-67 0.0048 0.0087 0.012
Onchocerca volvulus 0.0033 0.0043 0.048
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0092 0.0127
Entamoeba histolytica hypothetical protein 0.0106 0.0261 0.0362
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Trichomonas vaginalis helicase, putative 0.004 0.0063 0.0087
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0114 0.0285 0.0395
Loa Loa (eye worm) hypothetical protein 0.0091 0.0217 0.03
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0044 0.0074 0.0102
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Entamoeba histolytica acyl-CoA synthetase, putative 0.0149 0.0388 0.0538
Brugia malayi hypothetical protein 0.0048 0.0087 0.012
Plasmodium vivax SET domain protein, putative 0.0033 0.0043 0.0057
Loa Loa (eye worm) hypothetical protein 0.0039 0.006 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0063 0.0087
Schistosoma mansoni hypothetical protein 0.0081 0.0187 0.0259
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0051 0.0097 0.0134
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0017 0.0022
Echinococcus granulosus g protein coupled receptor 0.0051 0.0097 0.0134
Echinococcus multilocularis geminin 0.0338 0.0957 0.0957
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0051 0.0097 0.0134
Mycobacterium ulcerans acyl-CoA synthetase 0.0044 0.0074 0.0237
Echinococcus granulosus replication factor c subunit 1 0.002 0.0002 0.0003
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0035 0.0048 0.0064
Trichomonas vaginalis pyruvate kinase, putative 0.0039 0.006 0.0083
Onchocerca volvulus 0.0051 0.0097 0.1085
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0171 0.0237
Echinococcus granulosus pyruvate kinase 0.002 0.0003 0.0004
Brugia malayi Serotonin receptor 0.0051 0.0097 0.0134
Schistosoma mansoni hypothetical protein 0.004 0.0063 0.0087
Schistosoma mansoni neuropeptide receptor 0.0051 0.0097 0.0134
Echinococcus multilocularis muscleblind protein 1 0.0174 0.0466 0.0466
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0106 0.0261 0.0261
Brugia malayi hypothetical protein 0.0036 0.0051 0.0071
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Loa Loa (eye worm) ctsf protein 0.0035 0.0048 0.0067
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0102 0.0248 0.0248
Brugia malayi nuclear receptor NHR-88 0.0048 0.0087 0.012
Echinococcus multilocularis lysosomal alpha glucosidase 0.0342 0.0969 0.0969
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0051 0.0097 0.0097
Echinococcus granulosus cathepsin l cysteine peptidase 0.0035 0.0048 0.0067
Onchocerca volvulus Cathepsin L homolog 0.0035 0.0048 0.0536
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0063 0.0087
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0002 0.0003
Schistosoma mansoni neuropeptide receptor 0.0051 0.0097 0.0134
Onchocerca volvulus 0.0035 0.0048 0.0536
Schistosoma mansoni cathepsin F (C01 family) 0.0023 0.0013 0.0019
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.002 0.0002 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0048 0.0067
Onchocerca volvulus 0.0051 0.0097 0.1085
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0024 0.0033
Trypanosoma cruzi prenyl protein specific carboxyl methyltransferase, putative 0.2426 0.7216 1
Schistosoma mansoni amine GPCR 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0091 0.0217 0.03
Echinococcus multilocularis survival motor neuron protein 1 0.0473 0.136 0.136
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0111 0.0276 0.0448
Echinococcus multilocularis beta LACTamase domain containing family member 0.0196 0.0531 0.0531
Trypanosoma cruzi DNA repair protein, putative 0.0039 0.0059 0.0082
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0171 0.0237
Plasmodium falciparum zinc finger protein, putative 0.0025 0.0018 0.0022
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0017 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0097 0.0134
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0097 0.0097
Brugia malayi PHD-finger family protein 0.0065 0.0137 0.0189
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0044 0.0074 0.0102
Brugia malayi DKFZp564C0469 protein 0.002 0.0002 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0149 0.0388 0.0538
Mycobacterium tuberculosis Conserved protein 0.0196 0.0531 0.0863
Schistosoma mansoni growth hormone secretagogue receptor 0.0051 0.0097 0.0134
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0097 0.0097
Schistosoma mansoni patched 1 0.0084 0.0196 0.0272
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0097 0.0097
Schistosoma mansoni zinc finger protein 0.0053 0.0102 0.0141
Onchocerca volvulus Matrilysin homolog 0.0202 0.055 0.6175
Brugia malayi beta-lactamase 0.0196 0.0531 0.0736
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0048 0.0087 0.012
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0102 0.0248 0.0343
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0019
Loa Loa (eye worm) intermediate filament protein 0.003 0.0033 0.0046
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0102 0.0248 0.0343
Schistosoma mansoni cpg binding protein 0.0191 0.0515 0.0713
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0043 0.006
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0048 0.0087 0.0087
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0063 0.0087
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0063 0.0087
Trypanosoma cruzi pyruvate kinase 2, putative 0.0039 0.006 0.0083
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0002 0.0003
Mycobacterium ulcerans hypothetical protein 0.1059 0.3118 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0028 0.0028 0.0038
Entamoeba histolytica hypothetical protein 0.0025 0.0018 0.0025
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0044 0.0074 0.0237
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0102 0.0248 0.0343
Leishmania major DNA polymerase eta, putative 0.0044 0.0075 0.0104
Mycobacterium ulcerans hypothetical protein 0.0196 0.0531 0.1704
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0344 0.0476
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0149 0.0388 0.1246
Echinococcus multilocularis muscleblind protein 0.0174 0.0466 0.0466
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0149 0.0388 0.1793
Plasmodium vivax pyruvate kinase 2, putative 0.002 0.0003 0.0001
Echinococcus multilocularis neuropeptide FF receptor 2 0.0051 0.0097 0.0097
Loa Loa (eye worm) pyruvate kinase 0.0039 0.006 0.0083
Leishmania major cysteine peptidase A (CPA) 0.0035 0.0048 0.0067
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0092 0.0127
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0024 0.0033
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0033 0.0046
Echinococcus multilocularis tumor protein p63 0.0721 0.2104 0.2104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0102 0.0248 0.0343
Loa Loa (eye worm) MH2 domain-containing protein 0.0251 0.0695 0.0963
Echinococcus multilocularis thyroid hormone receptor alpha 0.0102 0.0248 0.0248
Brugia malayi Protein kinase domain containing protein 0.0032 0.004 0.0056
Brugia malayi Steroid receptor seven-up type 2 0.0102 0.0248 0.0343
Echinococcus granulosus beta LACTamase domain containing family member 0.0196 0.0531 0.0736
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0111 0.0276 0.8599
Brugia malayi Papain family cysteine protease containing protein 0.0035 0.0048 0.0067
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0144
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0048 0.0087 0.0087
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0024 0.0033
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0028 0.0039
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0149 0.0388 0.0631
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0022 0.0009 0.0012
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0051 0.0097 0.0134
Schistosoma mansoni neuropeptide receptor 0.0051 0.0097 0.0134
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0102 0.0248 0.0343
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Toxoplasma gondii hypothetical protein 0.0048 0.0087 0.0118
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0097 0.0097
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0035 0.0048 0.0067
Loa Loa (eye worm) hypothetical protein 0.0149 0.0388 0.0538
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0035 0.0048 0.0067
Schistosoma mansoni zinc finger protein 0.0048 0.0087 0.012
Trypanosoma brucei hypothetical protein, conserved 0.0196 0.0531 0.0736
Loa Loa (eye worm) hypothetical protein 0.0196 0.0531 0.0736
Brugia malayi hypothetical protein 0.0051 0.0097 0.0134
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0022 0.0009 0.0012
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0044 0.0074 0.0333
Mycobacterium leprae PROBABLE HYDROLASE 0.0111 0.0276 0.1273
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0051 0.0097 0.0134
Echinococcus granulosus nuclear receptor nhr 48 0.0048 0.0087 0.012
Brugia malayi Matrixin family protein 0.0091 0.0217 0.03
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0051 0.0097 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Schistosoma mansoni opsin-like receptor 0.0051 0.0097 0.0134
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0048 0.0048
Brugia malayi Serotonin receptor 0.0051 0.0097 0.0134
Brugia malayi hypothetical protein 0.0051 0.0097 0.0134
Trichomonas vaginalis sucrase-isomaltase, putative 0.0076 0.0171 0.0237
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0144
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Leishmania major glycosyl hydrolase-like protein 0.0028 0.0028 0.0038
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0149 0.0388 0.1246
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0068 0.0095
Leishmania major cathepsin L-like protease 0.0134 0.0344 0.0476
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0092 0.0127
Loa Loa (eye worm) hypothetical protein 0.0032 0.0039 0.0054
Echinococcus granulosus lysosomal alpha glucosidase 0.0342 0.0969 0.1343
Loa Loa (eye worm) matrix metalloproteinase 0.0091 0.0217 0.03
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0298 0.0836 0.1158
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0044 0.0074 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0023 0.0013 0.0019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0097 0.0097
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0044 0.0074 0.0102
Loa Loa (eye worm) protein-S isoprenylcysteine O-methyltransferase 0.2426 0.7216 1
Schistosoma mansoni bromodomain containing protein 0.0019 0.0001 0.0002
Onchocerca volvulus 0.0102 0.0248 0.278
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0097 0.0097
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0096 0.0232 0.0321
Brugia malayi G-protein coupled receptor 0.0051 0.0097 0.0134
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0017 0.0024
Trypanosoma brucei glucosidase, putative 0.0076 0.0171 0.0237
Schistosoma mansoni hypothetical protein 0.0051 0.0097 0.0134
Onchocerca volvulus Netrin receptor homolog 0.0032 0.0039 0.0431
Loa Loa (eye worm) hypothetical protein 0.0068 0.0146 0.0202
Brugia malayi Uncoordinated protein 44 0.0032 0.0039 0.0054
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0344 0.0476
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0002 0.0003
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.021 0.0573 0.0794
Leishmania major pyruvate kinase 0.0039 0.006 0.0083
Brugia malayi neuropeptide F receptor 0.0051 0.0097 0.0134
Echinococcus multilocularis g protein coupled receptor 0.0051 0.0097 0.0097
Echinococcus multilocularis dnaJ subfamily B 0.2072 0.6154 0.6154
Toxoplasma gondii t-complex protein beta subunit 0.0027 0.0024 0.003
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0048 0.0087 0.0087
Echinococcus granulosus pyruvate kinase 0.002 0.0003 0.0004
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0028 0.0038
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0044 0.0074 0.0102
Echinococcus granulosus tm gpcr rhodopsin 0.0051 0.0097 0.0134
Schistosoma mansoni hypothetical protein 0.0081 0.0187 0.0259
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0044 0.0074 0.0237
Brugia malayi nuclear receptor NHR-67 0.0048 0.0087 0.012
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0076 0.0171 0.0237
Onchocerca volvulus 0.0048 0.0087 0.097
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0022 0.0009 0.0009
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0044 0.0074 0.012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0097 0.0134
Onchocerca volvulus 0.0051 0.0097 0.1085
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0097 0.0097
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0097 0.0134
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0044 0.0074 0.0102
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0074 0.012
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0144
Onchocerca volvulus Neuropeptide F receptor homolog 0.0051 0.0097 0.1085
Brugia malayi hypothetical protein 0.0054 0.0104 0.0144
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0063 0.0087
Loa Loa (eye worm) hypothetical protein 0.0044 0.0074 0.0102
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0092 0.0127
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0017 0.0024
Echinococcus granulosus cathepsin l1 0.0023 0.0013 0.0019
Trypanosoma cruzi cysteine peptidase, putative 0.0035 0.0048 0.0067
Brugia malayi glutaminase DH11.1 0.0298 0.0838 0.1161
Schistosoma mansoni survival motor neuron protein 0.0096 0.0232 0.0321
Brugia malayi cathepsin L-like precursor 0.0023 0.0013 0.0019
Echinococcus granulosus sterol regulatory element binding protein 0.0084 0.0196 0.0272
Echinococcus multilocularis lamin dm0 0.003 0.0033 0.0033
Echinococcus multilocularis nibrin 0.002 0.0002 0.0002
Echinococcus granulosus cathepsin L cysteine proteinase 0.0035 0.0048 0.0067
Schistosoma mansoni hypothetical protein 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Leishmania major cathepsin L-like protease 0.0035 0.0048 0.0067
Entamoeba histolytica cysteine proteinase, putative 0.0035 0.0048 0.0067
Schistosoma mansoni hypothetical protein 0.0033 0.0043 0.006
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0032 0.0039 0.0039
Loa Loa (eye worm) neuropeptide F receptor 0.0051 0.0097 0.0134
Schistosoma mansoni hypothetical protein 0.0338 0.0957 0.1326
Trichomonas vaginalis penicillin-binding protein, putative 0.0196 0.0531 0.0736
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.002 0.0002 0.0003
Onchocerca volvulus 0.0051 0.0097 0.1085
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0196 0.0531 0.0736
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0051 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0111 0.0276 0.0383
Trypanosoma cruzi pyruvate kinase 2, putative 0.0039 0.006 0.0083
Echinococcus granulosus serotonin receptor 0.0051 0.0097 0.0134
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0101 0.0247 0.0342
Schistosoma mansoni biogenic amine (5HT) receptor 0.0051 0.0097 0.0134
Echinococcus multilocularis cysteine protease 0.0035 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0102 0.0248 0.0343
Echinococcus multilocularis G protein coupled receptor 139 0.0051 0.0097 0.0097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0097 0.0097
Onchocerca volvulus 0.0035 0.0048 0.0536
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0092 0.0092
Onchocerca volvulus 0.0239 0.0658 0.7394
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0063 0.0087
Echinococcus granulosus orexin receptor type 2 0.0051 0.0097 0.0134
Echinococcus multilocularis pyruvate kinase 0.0039 0.006 0.006
Trichomonas vaginalis protein-S isoprenylcysteine O-methyltransferase, putative 0.2426 0.7216 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0048 0.0067
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0114 0.0285 0.0395
Plasmodium vivax pyruvate kinase, putative 0.0039 0.006 0.008
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0063 0.0063
Trichomonas vaginalis glutaminase, putative 0.0298 0.0838 0.1161
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0027 0.0024 0.003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0097 0.0134
Entamoeba histolytica prenyl cysteine carboxyl methyltransferase, putative 0.2426 0.7216 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0102 0.0248 0.0248
Plasmodium vivax vivapain-2 0.0035 0.0048 0.0064
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0051 0.0097 0.0134
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0141 0.0366 0.0507
Giardia lamblia TCP-1 chaperonin subunit beta 0.0027 0.0024 0.0033
Mycobacterium leprae conserved hypothetical protein 0.0196 0.0531 0.2456
Onchocerca volvulus 0.0196 0.0531 0.5966
Onchocerca volvulus 0.0091 0.0217 0.2429
Loa Loa (eye worm) latrophilin receptor protein 2 0.0114 0.0285 0.0395
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0051 0.0097 0.0134
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0063 0.0087
Echinococcus granulosus nuclear factor of activated T cells 5 0.0313 0.0881 0.1221
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0022 0.0009 0.0012
Loa Loa (eye worm) matrixin family protein 0.0221 0.0605 0.0838
Schistosoma mansoni hypothetical protein 0.0051 0.0097 0.0134
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0035 0.0048 0.0067
Onchocerca volvulus Bile acid receptor homolog 0.0102 0.0248 0.278
Onchocerca volvulus 0.0051 0.0097 0.1085
Brugia malayi hypothetical protein 0.0051 0.0097 0.0134
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0035 0.0048 0.0048
Onchocerca volvulus 0.0051 0.0097 0.1085
Echinococcus granulosus Protein patched homolog 1 0.0084 0.0196 0.0272
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0102 0.0248 0.0343
Schistosoma mansoni topbp1 0.002 0.0002 0.0003
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0101 0.0247 0.0247
Echinococcus multilocularis FTZ F1 alpha 0.0102 0.0248 0.0248
Brugia malayi hypothetical protein 0.0473 0.136 0.1884
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0063 0.0087
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0051 0.0097 0.0134
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0063 0.0084
Entamoeba histolytica acyl-CoA synthetase, putative 0.0149 0.0388 0.0538
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0007 0.001
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0048 0.0087 0.012
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0028 0.0038
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0102 0.0248 0.0343
Trichomonas vaginalis ap endonuclease, putative 0.0022 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0097 0.0134
Toxoplasma gondii exonuclease III APE 0.0022 0.0009 0.0009
Brugia malayi Dopamine receptor 0.0051 0.0097 0.0134
Loa Loa (eye worm) hypothetical protein 0.0197 0.0533 0.0738
Brugia malayi Cathepsin L-like precursor 0.0035 0.0048 0.0067
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0044 0.0074 0.0333
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0344 0.0476
Loa Loa (eye worm) matrixin family protein 0.0202 0.055 0.0762
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0076 0.0171 0.0237
Schistosoma mansoni pyruvate kinase 0.0039 0.006 0.0083
Brugia malayi nuclear receptor RXR 0.0054 0.0104 0.0144
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0022 0.0009 0.0012
Echinococcus multilocularis nuclear receptor nhr 48 0.0048 0.0087 0.0087
Schistosoma mansoni myst-related protein 0.0025 0.0018 0.0025
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0059 0.0121 0.0121
Toxoplasma gondii isoprenylcysteine carboxyl methyltransferase (icmt) family protein 0.2426 0.7216 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0035 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Onchocerca volvulus 0.0196 0.0531 0.5966
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0022 0.0009 0.0012
Loa Loa (eye worm) hypothetical protein 0.0174 0.0466 0.0645
Onchocerca volvulus 0.0023 0.0013 0.0145
Schistosoma mansoni hypothetical protein 0.0247 0.0682 0.0945
Loa Loa (eye worm) hypothetical protein 0.0102 0.0248 0.0343
Toxoplasma gondii cathepsin CPL 0.0035 0.0048 0.0064
Brugia malayi CXXC zinc finger family protein 0.0176 0.0472 0.0654
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0002 0.0003
Schistosoma mansoni alpha-glucosidase 0.0295 0.0826 0.1145
Leishmania major cathepsin L-like protease 0.0035 0.0048 0.0067
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.1947 0.5779 0.9387
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0036 0.0047
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0074 0.012
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0063 0.0087
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0051 0.0097 0.0097
Trypanosoma cruzi cysteine peptidase, putative 0.0134 0.0344 0.0476
Giardia lamblia Pyruvate kinase 0.0039 0.006 0.0083
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0097 0.0134
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0111 0.0276 0.0885
Brugia malayi Glycosyl hydrolases family 31 protein 0.0342 0.0969 0.1343
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0048 0.0087 0.097
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0134 0.0344 0.0476
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Trichomonas vaginalis D-aminoacylase, putative 0.0196 0.0531 0.0736
Echinococcus granulosus neutral alpha glucosidase AB 0.0076 0.0171 0.0237
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0022 0.0009 0.0012
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0104 0.0144
Loa Loa (eye worm) hypothetical protein 0.0029 0.0031 0.0043
Loa Loa (eye worm) hypothetical protein 0.0023 0.0013 0.0019
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0045 0.0078 0.0108
Echinococcus multilocularis rhodopsin orphan GPCR 0.0051 0.0097 0.0097
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0044 0.0074 0.012
Brugia malayi Niemann-Pick C1 protein precursor 0.0197 0.0533 0.0738
Loa Loa (eye worm) hypothetical protein 0.0091 0.0217 0.03
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0017 0.0022
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0071 0.0155 0.0215
Trypanosoma brucei pyruvate kinase 1, putative 0.0039 0.006 0.0083
Leishmania major T-complex protein 1, beta subunit, putative 0.0027 0.0024 0.0033
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0022 0.0009 0.0214
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0097 0.0134
Onchocerca volvulus 0.0198 0.0537 0.6025
Brugia malayi steroid hormone receptor 0.0102 0.0248 0.0343
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0051 0.0097 0.0134
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0126 0.032 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0171 0.0237
Brugia malayi Nuclear hormone receptor E75 0.0048 0.0087 0.012
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Trichomonas vaginalis set domain proteins, putative 0.0239 0.0658 0.0912
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0141 0.0365 0.0506
Onchocerca volvulus 0.003 0.0033 0.0364
Schistosoma mansoni hypothetical protein 0.0051 0.0097 0.0134
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0063 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Mycobacterium leprae Probable pyruvate kinase PykA 0.0039 0.006 0.0268
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0298 0.0836 0.1158
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0063 0.0087
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0032 0.0039 0.0054
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0048 0.0087 0.012
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Onchocerca volvulus 0.0035 0.0048 0.0536
Onchocerca volvulus 0.0051 0.0097 0.1085
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0054 0.0104 0.0144
Loa Loa (eye worm) G-protein coupled receptor 0.0051 0.0097 0.0134
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0092 0.0127
Brugia malayi Death domain containing protein 0.0032 0.0039 0.0054
Schistosoma mansoni amine GPCR 0.0051 0.0097 0.0134
Schistosoma mansoni microtubule-associated protein tau 0.2058 0.6113 0.8472
Echinococcus multilocularis neuropeptides capa receptor 0.0051 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0022 0.0009 0.0012
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0048 0.0087 0.012
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.002 0.0002 0.0006
Leishmania major hypothetical protein, conserved 0.0033 0.0043 0.006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0051 0.0097 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0035 0.0048 0.0067
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0079 0.0179 0.0248
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Leishmania major alpha glucosidase II subunit, putative 0.0076 0.0171 0.0237
Schistosoma mansoni niemann-pick C1 (NPC1) 0.02 0.0542 0.0751
Brugia malayi GnHR receptor homolog 0.0051 0.0097 0.0134
Loa Loa (eye worm) nuclear hormone receptor 0.0048 0.0087 0.012
Leishmania major cathepsin L-like protease 0.0035 0.0048 0.0067
Loa Loa (eye worm) hypothetical protein 0.0102 0.0248 0.0343
Leishmania major prenyl protein specific carboxyl methyltransferase, putative 0.2426 0.7216 1
Echinococcus granulosus g-protein coupled receptor 0.0051 0.0097 0.0134
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0044 0.0074 0.0237
Loa Loa (eye worm) pyruvate kinase 0.0039 0.006 0.0083
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0044 0.0074 0.0102
Entamoeba histolytica hypothetical protein 0.0106 0.0261 0.0362
Loa Loa (eye worm) transcription factor SMAD2 0.0251 0.0695 0.0963
Brugia malayi latrophilin 2 splice variant baaae 0.0247 0.0682 0.0945
Echinococcus granulosus pyruvate kinase 0.0039 0.006 0.0083
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0044 0.0074 0.0102
Trypanosoma cruzi hypothetical protein, conserved 0.0196 0.0531 0.0736
Echinococcus granulosus rhodopsin orphan GPCR 0.0051 0.0097 0.0134
Entamoeba histolytica cysteine proteinase, putative 0.0023 0.0013 0.0019
Brugia malayi Matrixin family protein 0.0091 0.0217 0.03
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.0063 0.0087
Brugia malayi hypothetical protein 0.0126 0.032 0.0444
Schistosoma mansoni cellular tumor antigen P53 0.0106 0.0259 0.0359
Loa Loa (eye worm) hypothetical protein 0.0111 0.0276 0.0382
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0084 0.0196 0.0272
Brugia malayi beta-lactamase family protein 0.0196 0.0531 0.0736
Brugia malayi nuclear receptor RXR 0.0048 0.0087 0.012
Schistosoma mansoni myst-related protein 0.0025 0.0018 0.0025
Brugia malayi AMP-binding enzyme family protein 0.0149 0.0388 0.0538
Loa Loa (eye worm) hypothetical protein 0.0149 0.0388 0.0538
Brugia malayi nuclear hormone receptor 0.0048 0.0087 0.012
Brugia malayi nuclear receptor NHR-88 0.0102 0.0248 0.0343
Giardia lamblia Replication factor C, subunit 1 0.002 0.0002 0.0003
Echinococcus multilocularis GPCR, family 2 0.0114 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.0102 0.0248 0.0343
Mycobacterium leprae Probable lipase LipE 0.0196 0.0531 0.2456
Loa Loa (eye worm) hypothetical protein 0.0048 0.0087 0.012
Loa Loa (eye worm) hypothetical protein 0.002 0.0002 0.0003
Echinococcus granulosus neuropeptide receptor A26 0.1013 0.2981 0.4131
Brugia malayi G protein-coupled receptor F59B2.13 0.0051 0.0097 0.0134
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0056 0.011 0.0152
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0044 0.0074 0.01
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0044 0.0074 0.012
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0134
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0114 0.0285 0.0395

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 21 nM Displacement of fluormone from human recombinant glucocorticoid receptor ligand binding domain by fluorescence polarization assay ChEMBL. 19610652

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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