Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | musashi | 0.0026 | 0.2628 | 0.2628 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.2628 | 0.2628 |
Echinococcus granulosus | lamin | 0.0026 | 0.2628 | 0.2628 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.2628 | 0.2628 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.2628 | 0.2628 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.654 | 0.6444 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.2628 | 0.2423 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.654 | 0.654 |
Echinococcus multilocularis | lamin | 0.0026 | 0.2628 | 0.2628 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.2628 | 0.2423 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.654 | 0.5306 |
Onchocerca volvulus | 0.0026 | 0.2628 | 0.5 | |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.2628 | 0.2628 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.027 | 0.027 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.2628 | 0.2628 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.2535 | 0.2535 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.654 | 0.654 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.2628 | 0.2628 |
Onchocerca volvulus | 0.0026 | 0.2628 | 0.5 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.654 | 0.654 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.654 | 0.654 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.654 | 0.5306 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.654 | 0.5306 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.654 | 0.654 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | = 32 % | Displacement of [125I]-(D-Trp6)-GnRH from human GnRH receptor at 50 nM | ChEMBL. | 19251413 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.