Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.003 | 0.0206 | 0.0442 |
Brugia malayi | nuclear receptor NHR-88 | 0.003 | 0.0206 | 0.0235 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0372 | 0.142 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0191 | 0.2504 | 0.2347 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0627 | 0.1924 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0341 | 0.4649 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.2168 | 0.1909 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0246 | 0.0281 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0053 | 0.053 | 0.4744 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0053 | 0.053 | 0.7351 |
Brugia malayi | Pre-SET motif family protein | 0.009 | 0.1059 | 0.1209 |
Schistosoma mansoni | lamin | 0.0032 | 0.0221 | 0.0845 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.003 | 0.0206 | 0.0235 |
Onchocerca volvulus | 0.0094 | 0.1123 | 0.0936 | |
Schistosoma mansoni | retinoic acid receptor RXR | 0.003 | 0.0206 | 0.0784 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0467 | 0.0533 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.2297 | 0.2042 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.003 | 0.0206 | 0.0235 |
Brugia malayi | follicle stimulating hormone receptor | 0.024 | 0.3207 | 0.3661 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0206 | 0.0235 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.024 | 0.3207 | 0.3661 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.032 | 0.0601 |
Echinococcus granulosus | glycogen synthase kinase 3 beta | 0.0094 | 0.1123 | 0.2415 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0017 | 0.0012 | 0.0013 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0372 | 0.024 |
Onchocerca volvulus | 0.009 | 0.1059 | 0.0871 | |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1059 | 0.1209 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0094 | 0.1123 | 0.3677 |
Entamoeba histolytica | protein kinase, putative | 0.0094 | 0.1123 | 0.3677 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.093 | 1 |
Trypanosoma cruzi | glycogen synthase kinase 3, putative | 0.0094 | 0.1123 | 0.4057 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.1606 | 0.613 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.009 | 0.1059 | 0.4042 |
Schistosoma mansoni | lamin | 0.0032 | 0.0221 | 0.0845 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0032 | 0.0221 | 0.0253 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0191 | 0.2504 | 0.2256 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0206 | 0.0235 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0627 | 0.4801 |
Echinococcus granulosus | lamin | 0.0032 | 0.0221 | 0.0476 |
Brugia malayi | Pre-SET motif family protein | 0.0628 | 0.8758 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0094 | 0.1123 | 0.083 |
Loa Loa (eye worm) | intermediate filament protein | 0.0032 | 0.0221 | 0.0253 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.113 | 0.0837 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.009 | 0.1059 | 0.2278 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0191 | 0.2504 | 0.2859 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0191 | 0.2504 | 0.2256 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0081 | 0.093 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0206 | 0.0442 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0053 | 0.053 | 0.1141 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.032 | 0.122 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.003 | 0.0206 | 0.0235 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0191 | 0.2504 | 0.9556 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0053 | 0.053 | 0.1141 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.032 | 0.0601 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0081 | 0.093 | 0.7981 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0087 | 0.1012 | 0.2176 |
Echinococcus multilocularis | tar DNA binding protein | 0.0128 | 0.1606 | 0.3455 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.003 | 0.0206 | 0.0784 |
Onchocerca volvulus | 0.0032 | 0.0221 | 0.0016 | |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0627 | 0.1349 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0199 | 0.262 | 0.5636 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0255 | 0.3424 | 0.391 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.003 | 0.0206 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0341 | 0.4649 | 0.5308 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0206 | 0.0442 |
Brugia malayi | nuclear hormone receptor | 0.003 | 0.0206 | 0.0235 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.018 | 0.011 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0094 | 0.1123 | 0.083 |
Leishmania major | glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 | 0.0094 | 0.1123 | 0.4057 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.018 | 0.011 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0095 | 0.113 | 0.0837 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.009 | 0.1059 | 0.4042 |
Echinococcus granulosus | intermediate filament protein | 0.0032 | 0.0221 | 0.0476 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.018 | 0.011 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.0372 | 0.08 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0255 | 0.3424 | 0.3207 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0206 | 0.0235 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0206 | 0.0235 |
Trypanosoma brucei | polo-like protein kinase | 0.0191 | 0.2504 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0199 | 0.262 | 0.5636 |
Loa Loa (eye worm) | TAR-binding protein | 0.0128 | 0.1606 | 0.1834 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.003 | 0.0206 | 0.0784 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0199 | 0.262 | 0.2992 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.032 | 0.0688 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0627 | 0.1349 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0191 | 0.2504 | 0.2859 |
Echinococcus granulosus | protein kinase shaggy | 0.0094 | 0.1123 | 0.2415 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0206 | 0.0442 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0372 | 0.024 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.009 | 0.1059 | 0.2278 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0188 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0341 | 0.4649 | 0.5308 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0191 | 0.2504 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.093 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.2168 | 0.1909 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.003 | 0.0206 | 0.0235 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0255 | 0.3424 | 0.3207 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.1606 | 0.613 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0081 | 0.093 | 0.355 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0255 | 0.3424 | 0.391 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0255 | 0.3424 | 0.3207 |
Brugia malayi | Muscleblind-like protein | 0.0341 | 0.4649 | 0.5308 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0191 | 0.2504 | 0.2256 |
Echinococcus multilocularis | glycogen synthase kinase 3 beta | 0.0094 | 0.1123 | 0.2415 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0255 | 0.3424 | 0.3207 |
Echinococcus multilocularis | protein kinase shaggy | 0.0094 | 0.1123 | 0.2415 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0.0206 | 0.0784 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0081 | 0.093 | 0.2001 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0191 | 0.2504 | 0.2256 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0094 | 0.1123 | 0.3677 |
Brugia malayi | TAR-binding protein | 0.0128 | 0.1606 | 0.1834 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.003 | 0.0206 | 0.0784 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0176 | 0.2297 | 0.2042 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.1606 | 0.613 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.003 | 0.0206 | 0.0235 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0191 | 0.2504 | 0.2256 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0206 | 0.0235 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0191 | 0.2504 | 0.5386 |
Brugia malayi | Inositol-1 | 0.0038 | 0.032 | 0.0365 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.032 | 0.0365 |
Schistosoma mansoni | kinase | 0.0097 | 0.1166 | 0.4449 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0255 | 0.3424 | 0.3207 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.003 | 0.0206 | 0.0784 |
Echinococcus multilocularis | FTZ F1 alpha | 0.003 | 0.0206 | 0.0442 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.003 | 0.0206 | 0.0235 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.003 | 0.0206 | 0.0442 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0206 | 0.0235 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0032 | 0.0221 | 0.0253 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.003 | 0.0206 | 0.0442 |
Echinococcus granulosus | FTZ F1 alpha | 0.003 | 0.0206 | 0.0442 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.003 | 0.0206 | 0.0235 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.093 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.032 | 0.0601 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0191 | 0.2504 | 0.5386 |
Plasmodium falciparum | glycogen synthase kinase 3 | 0.0094 | 0.1123 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.093 | 0.1062 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0206 | 0.0235 |
Plasmodium vivax | SET domain protein, putative | 0.009 | 0.1059 | 0.9332 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.003 | 0.0206 | 0.0235 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.003 | 0.0206 | 0.0784 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.2168 | 0.1909 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0128 | 0.1606 | 0.1834 |
Echinococcus multilocularis | lamin dm0 | 0.0032 | 0.0221 | 0.0476 |
Loa Loa (eye worm) | RNA binding protein | 0.0128 | 0.1606 | 0.1834 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0628 | 0.8758 | 1 |
Brugia malayi | RNA binding protein | 0.0128 | 0.1606 | 0.1834 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0627 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0206 | 0.0442 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0191 | 0.2504 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.0372 | 0.08 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0627 | 0.5037 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.003 | 0.0206 | 0.0442 |
Giardia lamblia | Kinase, PLK | 0.0191 | 0.2504 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.009 | 0.1059 | 0.2278 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0206 | 0.0235 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0467 | 0.0533 |
Onchocerca volvulus | 0.0032 | 0.0221 | 0.0016 | |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.0094 | 0.1123 | 0.1282 |
Brugia malayi | steroid hormone receptor | 0.003 | 0.0206 | 0.0235 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.093 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.003 | 0.0206 | 0.0235 |
Echinococcus granulosus | lamin dm0 | 0.0032 | 0.0221 | 0.0476 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0206 | 0.0442 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0206 | 0.0235 |
Echinococcus multilocularis | lamin | 0.0032 | 0.0221 | 0.0476 |
Brugia malayi | hypothetical protein | 0.014 | 0.1777 | 0.2029 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.009 | 0.1059 | 0.9332 |
Plasmodium vivax | glycogen synthase kinase 3, putative | 0.0094 | 0.1123 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.003 | 0.0206 | 0.0235 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0199 | 0.262 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0627 | 0.2394 |
Brugia malayi | hypothetical protein | 0.0029 | 0.018 | 0.0206 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.009 | 0.1059 | 0.4042 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0191 | 0.2504 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.2168 | 0.1909 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.1777 | 0.2029 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0206 | 0.0235 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0199 | 0.262 | 0.5636 |
Schistosoma mansoni | glycogen synthase kinase 3-related (gsk3) (cmgc group III) | 0.0094 | 0.1123 | 0.4285 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.003 | 0.0206 | 0.0235 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.003 | 0.0206 | 0.0235 |
Brugia malayi | ecdysteroid receptor | 0.003 | 0.0206 | 0.0235 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0206 | 0.0235 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0255 | 0.3424 | 0.3207 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.1777 | 0.2029 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0081 | 0.093 | 0.7981 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0627 | 0.2394 |
Trypanosoma brucei | protein kinase, putative | 0.0094 | 0.1123 | 0.4057 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0206 | 0.0442 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0627 | 0.5037 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.018 | 0.0206 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0167 | 0.2168 | 0.2003 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0246 | 0.0281 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0191 | 0.2504 | 0.2256 |
Loa Loa (eye worm) | steroid hormone receptor | 0.003 | 0.0206 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0467 | 0.0533 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0206 | 0.0235 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.003 | 0.0206 | 0.0442 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0199 | 0.262 | 0.2992 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0467 | 0.0533 |
Toxoplasma gondii | cell-cycle-associated protein kinase GSK, putative | 0.0094 | 0.1123 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0017 | 0.0012 | 0.0013 |
Schistosoma mansoni | coup transcription factor | 0.003 | 0.0206 | 0.0784 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.093 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.009 | 0.1059 | 0.4042 |
Echinococcus multilocularis | muscleblind protein | 0.0341 | 0.4649 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0341 | 0.4649 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.003 | 0.0206 | 0.0784 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.032 | 0.0601 |
Brugia malayi | intermediate filament protein | 0.0032 | 0.0221 | 0.0253 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0206 | 0.0235 |
Echinococcus granulosus | tar DNA binding protein | 0.0128 | 0.1606 | 0.3455 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.1606 | 0.613 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.003 | 0.0206 | 0.0235 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0206 | 0.0442 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0199 | 0.262 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.1606 | 0.613 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.093 | 0.7981 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0035 | 0.004 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0053 | 0.053 | 0.7351 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 0.0372 | 0.142 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.003 | 0.0206 | 0.0784 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0.0206 | 0.0784 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0081 | 0.093 | 0.2001 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0081 | 0.093 | 0.7981 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.003 | 0.0206 | 0.0235 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0034 | 0.0262 | 0.1215 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0206 | 0.0442 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0206 | 0.0442 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0213 | 0.0243 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.003 | 0.0206 | 0.0442 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0188 | 0.0215 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.2168 | 0.1909 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0191 | 0.2504 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.2168 | 0.1909 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.032 | 0.1574 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0372 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0206 | 0.0235 |
Schistosoma mansoni | nuclear hormone receptor | 0.003 | 0.0206 | 0.0784 |
Brugia malayi | Probable ClpP-like protease | 0.0081 | 0.093 | 0.1062 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0081 | 0.093 | 1 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0372 | 0.0425 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0191 | 0.2504 | 0.2256 |
Onchocerca volvulus | Huntingtin homolog | 0.014 | 0.1777 | 0.1605 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0199 | 0.262 | 0.5636 |
Echinococcus multilocularis | musashi | 0.0032 | 0.0221 | 0.0476 |
Brugia malayi | intracellular kinase | 0.0094 | 0.1123 | 0.1282 |
Onchocerca volvulus | Huntingtin homolog | 0.014 | 0.1777 | 0.1605 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0221 | 0.0253 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0128 | 0.1606 | 0.1834 |
Schistosoma mansoni | intermediate filament proteins | 0.0032 | 0.0221 | 0.0845 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.003 | 0.0206 | 0.0235 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.032 | 0.0688 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0199 | 0.262 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0372 | 0.024 |
Loa Loa (eye worm) | CMGC/GSK protein kinase | 0.0094 | 0.1123 | 0.1282 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0627 | 0.5037 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.003 | 0.0206 | 0.0235 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.032 | 0.122 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.003 | 0.0206 | 0.0784 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.018 | 0.011 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0167 | 0.2168 | 0.1909 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0206 | 0.0442 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0246 | 0.094 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.