Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0081 | 0.21 | 0.6181 |
Brugia malayi | Ets-domain containing protein | 0.0087 | 0.2292 | 0.2856 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0595 | 0.0539 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0066 | 0.1587 | 0.4672 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0122 | 0.3398 | 0.3951 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0025 | 0.0266 | 0.018 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0595 | 0.0539 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Mycobacterium ulcerans | hypothetical protein | 0.0043 | 0.0876 | 0.2579 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0087 | 0.2263 | 0.2584 |
Onchocerca volvulus | 0.0026 | 0.0302 | 0.0475 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0171 | 0.4971 | 0.4917 |
Brugia malayi | Protein kinase domain containing protein | 0.0034 | 0.0562 | 0.07 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0043 | 0.0876 | 0.0914 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0043 | 0.0876 | 0.085 |
Toxoplasma gondii | ubiquitin-conjugating enzyme subfamily protein | 0.0046 | 0.0959 | 0.3876 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0046 | 0.0959 | 0.1048 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0087 | 0.2292 | 0.2209 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0043 | 0.0876 | 0.0914 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0026 | 0.0302 | 0.0329 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0026 | 0.0302 | 0.0475 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0107 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0107 | 0.0117 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.2447 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.1552 | 0.6344 |
Schistosoma mansoni | ran | 0.0021 | 0.0144 | 0.004 |
Trypanosoma brucei | polo-like protein kinase | 0.0092 | 0.2447 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0278 | 0.8421 | 1 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0144 | 0.0108 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0107 | 0.0133 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0743 | 0.0703 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0211 | 0.0284 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0171 | 0.4971 | 0.4917 |
Brugia malayi | Animal haem peroxidase family protein | 0.0026 | 0.0302 | 0.0376 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0302 | 0.0376 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0107 | 0.0133 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.6065 | 0.6583 |
Brugia malayi | bZIP transcription factor family protein | 0.0171 | 0.4971 | 0.6194 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0087 | 0.2292 | 0.2209 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.1552 | 0.6344 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0081 | 0.21 | 0.6181 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0595 | 0.0742 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0301 | 0.9158 | 1 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0081 | 0.21 | 0.2388 |
Brugia malayi | hypothetical protein | 0.0134 | 0.3791 | 0.4724 |
Echinococcus granulosus | geminin | 0.0205 | 0.6065 | 0.6023 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0107 | 0.0133 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0107 | 0.0133 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0595 | 0.1886 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0144 | 0.0108 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0283 | 0.0352 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0107 | 0.0133 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0383 | 0.1565 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0092 | 0.2447 | 0.3049 |
Onchocerca volvulus | 0.0142 | 0.4043 | 0.9602 | |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0033 | 0.0552 | 0.0688 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.5866 |
Schistosoma mansoni | ubiquitin conjugating enzyme 13 | 0.0046 | 0.0959 | 0.0942 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.3884 | 0.4241 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0122 | 0.3398 | 1 |
Echinococcus multilocularis | 3 oxoacyl (acyl carrier protein) synthase | 0.002 | 0.0135 | 0.0028 |
Brugia malayi | Ets-domain containing protein | 0.0087 | 0.2292 | 0.2856 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.079 | 0.0691 |
Trypanosoma brucei | ubiquitin-protein ligase, putative | 0.0046 | 0.0959 | 0.3921 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.1884 | 0.2057 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0033 | 0.0537 | 0.0506 |
Mycobacterium ulcerans | polyketide synthase | 0.0081 | 0.21 | 0.6181 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0043 | 0.0876 | 0.0914 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0107 | 0.0117 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.1383 | 0.129 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0144 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0876 | 0.0957 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0147 | 0.4206 | 1 |
Mycobacterium ulcerans | thioesterase TesA | 0.0068 | 0.1663 | 0.4893 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0087 | 0.2263 | 0.666 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0595 | 0.1886 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0107 | 0.0133 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0876 | 0.0914 |
Mycobacterium leprae | Probable lipase LipE | 0.0043 | 0.0876 | 0.1859 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.6065 | 0.6583 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0144 | 0.0587 |
Schistosoma mansoni | netrin receptor unc5 | 0.0033 | 0.0552 | 0.0492 |
Brugia malayi | Fli-1 protein | 0.0265 | 0.8026 | 1 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0081 | 0.21 | 0.2388 |
Brugia malayi | AMP-binding enzyme family protein | 0.0076 | 0.1928 | 0.2402 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0033 | 0.0552 | 0.0603 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0876 | 0.0957 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0046 | 0.0959 | 0.3921 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0552 | 0.0603 |
Echinococcus multilocularis | geminin | 0.0205 | 0.6065 | 0.6023 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0107 | 0.0133 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0107 | 0.0133 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0081 | 0.21 | 0.581 |
Brugia malayi | Uncoordinated protein 44 | 0.0033 | 0.0552 | 0.0688 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Loa Loa (eye worm) | TAR-binding protein | 0.0076 | 0.1939 | 0.2118 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.002 | 0.0135 | 0.055 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0064 | 0.1552 | 0.6344 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0095 | 0.2539 | 0.2458 |
Mycobacterium tuberculosis | Polyketide synthetase MbtD (polyketide synthase) | 0.0025 | 0.0283 | 0.0199 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0144 | 0.0179 |
Leishmania major | beta-ketoacyl synthase family protein, putative,3-oxoacyl-acyl carrier protein synthase ii, putative | 0.002 | 0.0135 | 0.055 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.4071 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0026 | 0.0302 | 0.0329 |
Brugia malayi | ubiquitin conjugating enzyme protein 13 | 0.0046 | 0.0959 | 0.1196 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0552 | 0.0492 |
Brugia malayi | beta-lactamase | 0.0043 | 0.0876 | 0.1092 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0026 | 0.0302 | 0.0329 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0054 | 0.1211 | 0.3565 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0122 | 0.3398 | 0.3951 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0025 | 0.0266 | 0.018 |
Onchocerca volvulus | 0.0026 | 0.0302 | 0.0475 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0211 | 0.0864 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0046 | 0.0959 | 0.3542 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.1552 | 0.1461 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1939 | 0.2024 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.002 | 0.0135 | 0.0396 |
Mycobacterium ulcerans | 3-oxoacyl-(acyl carrier protein) synthase II | 0.002 | 0.0135 | 0.0396 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0107 | 0.0133 |
Brugia malayi | Animal haem peroxidase family protein | 0.0026 | 0.0302 | 0.0376 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0087 | 0.2263 | 0.2584 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0081 | 0.21 | 0.6181 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0092 | 0.2447 | 0.2365 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0043 | 0.0876 | 0.358 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0059 | 0.1361 | 0.1498 |
Echinococcus multilocularis | snurportin 1 | 0.0301 | 0.9158 | 0.9149 |
Onchocerca volvulus | 0.0043 | 0.0876 | 0.1876 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.0876 | 0.318 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0043 | 0.0876 | 0.318 |
Mycobacterium ulcerans | polyketide synthase MbtD | 0.0025 | 0.0283 | 0.0832 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0026 | 0.0302 | 0.0329 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0081 | 0.21 | 0.6181 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0107 | 0.0133 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0081 | 0.21 | 0.2388 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Loa Loa (eye worm) | beta-lactamase | 0.0043 | 0.0876 | 0.0957 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0383 | 0.0279 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0107 | 0.0133 |
Loa Loa (eye worm) | RNA binding protein | 0.0076 | 0.1939 | 0.2118 |
Echinococcus granulosus | jun protein | 0.0171 | 0.4971 | 0.4917 |
Entamoeba histolytica | ubiquitin-conjugating enzyme family protein | 0.0046 | 0.0959 | 0.3406 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0383 | 0.0305 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.482 | 0.5264 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0144 | 0.0157 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0383 | 0.1565 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0033 | 0.0552 | 0.045 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0383 | 0.0477 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0107 | 0.0117 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0081 | 0.21 | 0.581 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.0046 | 0.0959 | 0.1048 |
Schistosoma mansoni | peroxidasin | 0.0026 | 0.0302 | 0.0215 |
Brugia malayi | TAR-binding protein | 0.0076 | 0.1939 | 0.2416 |
Mycobacterium ulcerans | thioesterase | 0.0068 | 0.1663 | 0.4893 |
Loa Loa (eye worm) | fatty acid synthase | 0.008 | 0.2065 | 0.2255 |
Mycobacterium tuberculosis | Probable fatty acid synthase Fas (fatty acid synthetase) | 0.0026 | 0.03 | 0.0221 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1939 | 0.2024 |
Schistosoma mansoni | 3-oxoacyl-[ACP] synthase | 0.002 | 0.0135 | 0.003 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1939 | 0.2024 |
Brugia malayi | Blistered cuticle protein 3 | 0.0026 | 0.0302 | 0.0376 |
Echinococcus granulosus | ubiquitin conjugating enzyme E2 N | 0.0046 | 0.0959 | 0.0862 |
Brugia malayi | beta-lactamase family protein | 0.0043 | 0.0876 | 0.1092 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2539 | 0.2772 |
Mycobacterium ulcerans | fatty acid synthase Fas | 0.0026 | 0.03 | 0.0884 |
Onchocerca volvulus | Peroxidasin homolog | 0.0026 | 0.0302 | 0.0475 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0043 | 0.0876 | 0.0777 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Schistosoma mansoni | peroxidasin | 0.0026 | 0.0302 | 0.0215 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0876 | 0.0957 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.1383 | 0.5652 |
Loa Loa (eye worm) | fli-1 protein | 0.0265 | 0.8026 | 0.8764 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0211 | 0.0864 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0556 | 0.0608 |
Schistosoma mansoni | ran | 0.0021 | 0.0144 | 0.004 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0054 | 0.1211 | 0.2941 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0107 | 0.0133 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0058 | 0.1344 | 0.5682 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0043 | 0.0876 | 0.2579 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1939 | 0.2024 |
Echinococcus multilocularis | Ankyrin | 0.0034 | 0.0556 | 0.0454 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0053 | 0.1178 | 0.4903 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0092 | 0.2447 | 0.9617 |
Brugia malayi | Animal haem peroxidase family protein | 0.0026 | 0.0302 | 0.0376 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.079 | 0.2808 |
Brugia malayi | RNA, U transporter 1 | 0.008 | 0.2055 | 0.2561 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0043 | 0.0876 | 0.318 |
Schistosoma mansoni | gabp alpha | 0.0087 | 0.2292 | 0.2414 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0154 | 0.4449 | 0.5544 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0043 | 0.0876 | 0.085 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0081 | 0.21 | 0.2617 |
Onchocerca volvulus | 0.0134 | 0.3791 | 0.8987 | |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0876 | 0.0957 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0107 | 0.0117 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0037 | 0.0678 | 0.0577 |
Echinococcus multilocularis | ubiquitin conjugating enzyme E2 N | 0.0046 | 0.0959 | 0.0862 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0743 | 0.0703 |
Plasmodium vivax | ubiquitin-conjugating enzyme E2 N, putative | 0.0046 | 0.0959 | 1 |
Leishmania major | ubiquitin-conjugating enzyme e2, putative | 0.0046 | 0.0959 | 0.3921 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0076 | 0.1939 | 0.2118 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.1383 | 0.129 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0092 | 0.2447 | 0.2365 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0947 | 0.3487 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0876 | 0.358 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0743 | 0.0703 |
Onchocerca volvulus | Netrin receptor homolog | 0.0033 | 0.0552 | 0.1086 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0107 | 0.0133 |
Mycobacterium tuberculosis | Polyketide synthetase MbtC (polyketide synthase) | 0.0028 | 0.0378 | 0.0314 |
Brugia malayi | Ubiquitin conjugating enzyme protein 13 | 0.0046 | 0.0959 | 0.1196 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.2447 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0266 | 0.1089 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein synthase | 0.002 | 0.0135 | 0.0028 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0033 | 0.0552 | 0.045 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.2447 | 1 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0095 | 0.2539 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0026 | 0.0302 | 0.0475 |
Echinococcus granulosus | peroxidasin | 0.0026 | 0.0302 | 0.0197 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0064 | 0.1552 | 0.6344 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0064 | 0.1552 | 0.1461 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0107 | 0.0133 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.0046 | 0.0959 | 0.3921 |
Echinococcus granulosus | Ankyrin | 0.0034 | 0.0556 | 0.0454 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.079 | 0.0755 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0097 | 0.2586 | 0.2739 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0087 | 0.2292 | 0.2503 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0046 | 0.0968 | 0.1024 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0087 | 0.2263 | 0.666 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0068 | 0.1663 | 0.1861 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0383 | 0.0418 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0054 | 0.1211 | 0.3565 |
Plasmodium falciparum | ubiquitin-conjugating enzyme E2 N, putative | 0.0046 | 0.0959 | 1 |
Schistosoma mansoni | jun-related protein | 0.0139 | 0.3942 | 0.4237 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0383 | 0.1167 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0144 | 0.0587 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0107 | 0.0133 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0043 | 0.0876 | 0.0777 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0064 | 0.1552 | 0.5881 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0064 | 0.1552 | 0.1934 |
Brugia malayi | Peroxidasin | 0.0026 | 0.0302 | 0.0376 |
Brugia malayi | Death domain containing protein | 0.0033 | 0.0552 | 0.0688 |
Onchocerca volvulus | 0.0043 | 0.0876 | 0.1876 | |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.079 | 0.0691 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Leishmania major | hypothetical protein, conserved | 0.0043 | 0.0876 | 0.358 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0211 | 0.0295 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0211 | 0.0295 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.0046 | 0.0959 | 0.3542 |
Loa Loa (eye worm) | beta-ketoacyl synthase domain-containing protein | 0.002 | 0.0135 | 0.0147 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0043 | 0.0876 | 0.0914 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.002 | 0.0135 | 0.0168 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0043 | 0.0876 | 0.0914 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0043 | 0.0876 | 0.1092 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.1552 | 0.1695 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0068 | 0.1663 | 0.4398 |
Mycobacterium ulcerans | polyketide synthase MbtC | 0.002 | 0.0135 | 0.0396 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0107 | 0.0117 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0383 | 0.3011 |
Echinococcus granulosus | tar DNA binding protein | 0.0076 | 0.1939 | 0.1852 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0383 | 0.0279 |
Trypanosoma brucei | beta-ketoacyl-ACP synthase | 0.002 | 0.0135 | 0.055 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0743 | 0.0703 |
Schistosoma mansoni | hypothetical protein | 0.0301 | 0.9158 | 1 |
Schistosoma mansoni | ets-related | 0.0265 | 0.8026 | 0.8749 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0947 | 0.3487 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.0876 | 0.318 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0144 | 0.0042 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0107 | 0.0133 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0087 | 0.2263 | 0.6337 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0033 | 0.0552 | 0.0492 |
Mycobacterium ulcerans | lipase LipD | 0.0043 | 0.0876 | 0.2579 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0383 | 0.3011 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Echinococcus multilocularis | peroxidasin | 0.0026 | 0.0302 | 0.0197 |
Mycobacterium ulcerans | polyketide synthase | 0.0087 | 0.2263 | 0.666 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0595 | 0.0493 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0043 | 0.0876 | 0.0914 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0136 | 0.3853 | 0.3787 |
Schistosoma mansoni | tar DNA-binding protein | 0.0076 | 0.1939 | 0.2024 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0037 | 0.0678 | 0.0577 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.2447 | 0.2585 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0144 | 0.0587 |
Echinococcus multilocularis | expressed conserved protein | 0.0089 | 0.2353 | 0.227 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Echinococcus granulosus | expressed conserved protein | 0.0089 | 0.2353 | 0.227 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0107 | 0.0133 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.1525 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0064 | 0.1552 | 0.1597 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.141 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0079 | 0.202 | 0.2291 |
Mycobacterium leprae | conserved hypothetical protein | 0.0043 | 0.0876 | 0.1859 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0595 | 0.0493 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0876 | 0.0914 |
Onchocerca volvulus | Peroxidase homolog | 0.0026 | 0.0302 | 0.0475 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0107 | 0.0117 |
Toxoplasma gondii | ABC1 family protein | 0.0043 | 0.0876 | 0.3484 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0107 | 0.0133 |
Echinococcus multilocularis | jun protein | 0.0171 | 0.4971 | 0.4917 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0095 | 0.2539 | 0.3163 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0595 | 0.1886 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.11 | 0.1098 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.079 | 0.0691 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0092 | 0.2447 | 0.5709 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0107 | 0.0133 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0033 | 0.0552 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0876 | 0.0957 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0026 | 0.0302 | 0.0329 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.3942 | 0.4237 |
Schistosoma mansoni | kinase | 0.0047 | 0.0986 | 0.0971 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0144 | 0.0037 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0107 | 0.0117 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.079 | 0.0691 |
Onchocerca volvulus | 0.0043 | 0.0876 | 0.1876 | |
Onchocerca volvulus | Dual oxidase homolog | 0.0026 | 0.0302 | 0.0475 |
Brugia malayi | Methyltransferase-like protein 4 | 0.0025 | 0.0266 | 0.0332 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0211 | 0.0295 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.002 | 0.0135 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.0043 | 0.0876 | 0.1092 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0087 | 0.2263 | 0.2584 |
Brugia malayi | RNA binding protein | 0.0076 | 0.1939 | 0.2416 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0076 | 0.1928 | 0.218 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0043 | 0.0876 | 0.318 |
Loa Loa (eye worm) | acyl carrier protein | 0.0037 | 0.0683 | 0.0745 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0136 | 0.3853 | 0.3787 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0266 | 0.0534 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.141 |
Echinococcus granulosus | death domain containing protein | 0.0033 | 0.0552 | 0.045 |
Onchocerca volvulus | 0.0026 | 0.0302 | 0.0475 | |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0144 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.079 | 0.0863 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0076 | 0.1939 | 0.2416 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0092 | 0.2447 | 0.2672 |
Brugia malayi | Animal haem peroxidase family protein | 0.0026 | 0.0302 | 0.0376 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0043 | 0.0876 | 0.0957 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0087 | 0.2263 | 0.6337 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0107 | 0.0133 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0087 | 0.2263 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0095 | 0.2539 | 0.2458 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0976 | 0.0878 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.4071 |
Giardia lamblia | Kinase, PLK | 0.0092 | 0.2447 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0595 | 0.1886 |
Echinococcus granulosus | snurportin 1 | 0.0301 | 0.9158 | 0.9149 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0087 | 0.2263 | 0.6337 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.1383 | 0.4071 |
Plasmodium vivax | hypothetical protein, conserved | 0.0043 | 0.0876 | 0.899 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0107 | 0.0117 |
Onchocerca volvulus | 0.0076 | 0.1928 | 0.4441 | |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1086 | 0.1186 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0041 | 0.0802 | 0.3136 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0076 | 0.1928 | 0.2105 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.079 | 0.0985 |
Giardia lamblia | Methyltransferase like 2 | 0.0025 | 0.0266 | 0.0534 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0034 | 0.0556 | 0.0496 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0066 | 0.1587 | 0.4672 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0876 | 0.0957 |
Trichomonas vaginalis | esterase, putative | 0.0043 | 0.0876 | 0.318 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0043 | 0.0876 | 0.2579 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0043 | 0.0876 | 0.0914 |
Mycobacterium tuberculosis | Conserved protein | 0.0043 | 0.0876 | 0.0914 |
Onchocerca volvulus | Peroxidase homolog | 0.0026 | 0.0302 | 0.0475 |
Trypanosoma cruzi | beta-ketoacyl synthase family protein, putative | 0.002 | 0.0135 | 0.055 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.079 | 0.0863 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0066 | 0.1587 | 0.4155 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0946 | 0.1033 |
Mycobacterium ulcerans | beta-lactamase | 0.0043 | 0.0876 | 0.2579 |
Schistosoma mansoni | methyltransferase-related | 0.0025 | 0.0266 | 0.0176 |
Brugia malayi | Animal haem peroxidase family protein | 0.0026 | 0.0302 | 0.0376 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0122 | 0.3398 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0079 | 0.202 | 0.2291 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0067 | 0.1622 | 0.1812 |
Chlamydia trachomatis | 3-oxoacyl-ACP synthase | 0.002 | 0.0135 | 0.5 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0092 | 0.2447 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0302 | 0.0329 |
Echinococcus multilocularis | tar DNA binding protein | 0.0076 | 0.1939 | 0.1852 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0033 | 0.0552 | 0.045 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0043 | 0.0876 | 0.358 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.