Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.006 | 0.0877 | 0.0877 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1116 | 0.1116 |
Brugia malayi | Carboxylesterase family protein | 0.0013 | 0.0001 | 0.0001 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0134 | 0.0134 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.0521 | 0.0782 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0134 | 0.0134 |
Echinococcus multilocularis | carbonic anhydrase | 0.0117 | 0.1959 | 0.1959 |
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0177 | 0.309 | 0.5323 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0521 | 0.0521 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0134 | 0.0134 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0117 | 0.1959 | 0.1959 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0521 | 0.0521 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0018 | 0.0094 | 0.0733 |
Echinococcus multilocularis | carbonic anhydrase | 0.0117 | 0.1959 | 0.1959 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0134 | 0.0134 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0013 | 0.0001 | 0.0009 |
Leishmania major | methionine synthase, putative | 0.0135 | 0.2289 | 0.389 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0134 | 0.0134 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0134 | 0.0134 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0134 | 0.0134 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0041 | 0.0521 | 0.0521 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0085 | 0.1348 | 0.1348 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0521 | 0.0521 |
Brugia malayi | Dihydrofolate reductase | 0.0051 | 0.0716 | 0.0716 |
Schistosoma mansoni | acetylcholinesterase | 0.0013 | 0.0001 | 0.0001 |
Echinococcus multilocularis | thymidylate synthase | 0.0126 | 0.2122 | 0.2122 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0038 | 0.0473 | 0.0473 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0521 | 0.4046 |
Loa Loa (eye worm) | RecQ helicase | 0.002 | 0.0116 | 0.0116 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.002 | 0.0116 | 0.0175 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0041 | 0.0521 | 0.0782 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0117 | 0.1959 | 0.1959 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0098 | 0.1589 | 0.1589 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0117 | 0.1959 | 0.1959 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0041 | 0.0521 | 0.0782 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0316 | 0.5703 | 1 |
Brugia malayi | Fli-1 protein | 0.0258 | 0.4606 | 0.4606 |
Echinococcus granulosus | Ankyrin | 0.0014 | 0.0014 | 0.0014 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.0521 | 0.0724 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0521 | 0.0724 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0134 | 0.0134 |
Onchocerca volvulus | 0.0041 | 0.0521 | 0.2454 | |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0521 | 0.0521 |
Brugia malayi | Death domain containing protein | 0.0014 | 0.0011 | 0.0011 |
Brugia malayi | Protein kinase domain containing protein | 0.0014 | 0.0011 | 0.0011 |
Brugia malayi | Tnks protein | 0.0018 | 0.0097 | 0.0097 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0117 | 0.1959 | 0.1959 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0164 | 0.0246 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0134 | 0.0134 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0134 | 0.0134 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0134 | 0.0134 |
Echinococcus granulosus | carbonic anhydrase | 0.0117 | 0.1959 | 0.1959 |
Echinococcus granulosus | Chromobox protein 3 | 0.0013 | 0.000000015121 | 0.000000015121 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0134 | 0.0134 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0164 | 0.0246 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0013 | 0.0001 | 0.0001 |
Echinococcus multilocularis | acetylcholinesterase | 0.0079 | 0.1246 | 0.1246 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0051 | 0.0716 | 0.0716 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0014 | 0.0011 | 0.0011 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0134 | 0.0134 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.002 | 0.0116 | 0.0116 |
Echinococcus granulosus | chromobox protein 1 | 0.0082 | 0.1287 | 0.1287 |
Onchocerca volvulus | 0.0013 | 0.0001 | 0.0005 | |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0134 | 0.0629 |
Plasmodium vivax | hydroxymethylpterin pyrophosphokinase-dihydropteroate synthetase, putative | 0.0366 | 0.6645 | 1 |
Toxoplasma gondii | dihydropteroate synthase | 0.0366 | 0.6645 | 1 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0022 | 0.0164 | 0.0164 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0134 | 0.0134 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0022 | 0.0164 | 0.0164 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0022 | 0.0164 | 0.0245 |
Entamoeba histolytica | hypothetical protein | 0.0018 | 0.0094 | 0.0594 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0041 | 0.0521 | 0.0521 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0018 | 0.0094 | 0.0733 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0164 | 0.0164 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0013 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0001 | 0.0001 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0041 | 0.0521 | 0.0782 |
Brugia malayi | Carboxylesterase family protein | 0.0079 | 0.1246 | 0.1246 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0117 | 0.1959 | 0.1959 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0521 | 0.0782 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0134 | 0.0134 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0046 | 0.0611 | 0.4746 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0134 | 0.0134 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0316 | 0.5703 | 0.5703 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0014 | 0.0011 | 0.0011 |
Onchocerca volvulus | 0.0013 | 0.0001 | 0.0005 | |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0164 | 0.0164 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0134 | 0.0134 |
Trichomonas vaginalis | conserved hypothetical protein | 0.006 | 0.0877 | 0.6816 |
Mycobacterium tuberculosis | Hypothetical protein | 0.006 | 0.0877 | 0.1319 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0134 | 0.0134 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0051 | 0.0716 | 0.1076 |
Schistosoma mansoni | tankyrase | 0.0018 | 0.0097 | 0.0097 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0262 | 0.4685 | 0.705 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0134 | 0.0134 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0134 | 0.0134 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0014 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0134 | 0.0134 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0126 | 0.2122 | 0.2122 |
Echinococcus multilocularis | chromobox protein 1 | 0.0082 | 0.1287 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0134 | 0.0134 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0134 | 0.0134 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0164 | 0.0085 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0041 | 0.0521 | 0.0782 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0001 | 0.0001 |
Echinococcus multilocularis | poly (ADP ribose) polymerase | 0.0018 | 0.0094 | 0.0094 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0018 | 0.0094 | 0.0733 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0079 | 0.1246 | 0.1246 |
Plasmodium falciparum | carbonic anhydrase | 0.0117 | 0.1959 | 0.2948 |
Brugia malayi | hypothetical protein | 0.0013 | 0.0001 | 0.0001 |
Schistosoma mansoni | chromobox protein | 0.0082 | 0.1287 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0116 | 0.0116 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0041 | 0.0521 | 0.0782 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0134 | 0.0134 |
Mycobacterium ulcerans | lipase LipD | 0.0041 | 0.0521 | 0.0782 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0177 | 0.309 | 0.5323 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0116 | 0.0116 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0013 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | thymidylate synthase | 0.0126 | 0.2122 | 0.2122 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0134 | 0.0134 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0521 | 0.4046 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0134 | 0.0134 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0316 | 0.5703 | 0.5703 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0134 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | beta-lactamase | 0.0041 | 0.0521 | 0.0782 |
Brugia malayi | Uncoordinated protein 44 | 0.0014 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.002 | 0.0116 | 0.0116 |
Onchocerca volvulus | 0.0013 | 0.0001 | 0.0005 | |
Trichomonas vaginalis | chromobox protein, putative | 0.0082 | 0.1287 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.0164 | 0.1271 |
Brugia malayi | follicle stimulating hormone receptor | 0.0271 | 0.4865 | 0.4865 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0134 | 0.0134 |
Echinococcus granulosus | carbonic anhydrase | 0.0117 | 0.1959 | 0.1959 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0011 | 0.0011 |
Brugia malayi | hypothetical protein | 0.0013 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.1959 | 0.1959 |
Schistosoma mansoni | hypothetical protein | 0.0117 | 0.1959 | 0.1959 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0001 | 0.0001 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0051 | 0.0716 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0425 | 0.0425 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0085 | 0.1348 | 0.1348 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0049 | 0.0676 | 0.3188 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0072 | 0.1097 | 0.1097 |
Brugia malayi | Carboxylesterase family protein | 0.0013 | 0.0001 | 0.0001 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0022 | 0.0164 | 0.0085 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.002 | 0.0116 | 0.0902 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0134 | 0.0134 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0013 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0316 | 0.5703 | 0.5703 |
Echinococcus granulosus | WGR domain containing protein | 0.0038 | 0.0473 | 0.0473 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0022 | 0.0164 | 0.0164 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0134 | 0.0134 |
Echinococcus granulosus | tankyrase | 0.0018 | 0.0094 | 0.0094 |
Schistosoma mansoni | gabp alpha | 0.0085 | 0.1348 | 0.1348 |
Echinococcus granulosus | acetylcholinesterase | 0.0079 | 0.1246 | 0.1246 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0134 | 0.0134 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0177 | 0.309 | 0.5323 |
Schistosoma mansoni | gliotactin | 0.0013 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.1959 | 0.1959 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0134 | 0.0134 |
Schistosoma mansoni | chromobox protein | 0.0082 | 0.1287 | 0.1287 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0134 | 0.0134 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0134 | 0.0134 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0022 | 0.0164 | 0.103 |
Onchocerca volvulus | 0.0041 | 0.0521 | 0.2454 | |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0521 | 0.0521 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0.0164 | 0.5 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0521 | 0.0521 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0134 | 0.0134 |
Echinococcus granulosus | death domain containing protein | 0.0014 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1246 | 0.1246 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0521 | 0.4046 |
Onchocerca volvulus | 0.002 | 0.0134 | 0.0629 | |
Echinococcus granulosus | BC026374 protein S09 family | 0.0013 | 0.0001 | 0.0001 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0041 | 0.0521 | 0.0782 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0164 | 0.0085 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0079 | 0.1242 | 0.1242 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0134 | 0.0629 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0082 | 0.1287 | 0.1287 |
Loa Loa (eye worm) | carboxylesterase | 0.0079 | 0.1246 | 0.1246 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0134 | 0.0134 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0018 | 0.0094 | 0.0733 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0521 | 0.0521 |
Onchocerca volvulus | 0.0041 | 0.0521 | 0.2454 | |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.1959 | 0.1959 |
Loa Loa (eye worm) | carboxylesterase | 0.0013 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0117 | 0.1959 | 0.1959 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0041 | 0.0521 | 0.0782 |
Mycobacterium ulcerans | dihydropteroate synthase 2 FolP2 | 0.0135 | 0.2289 | 0.3444 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0126 | 0.2122 | 0.3192 |
Echinococcus multilocularis | bloom syndrome protein | 0.002 | 0.0116 | 0.0116 |
Schistosoma mansoni | dihydrofolate reductase | 0.0051 | 0.0716 | 0.0716 |
Plasmodium falciparum | hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase | 0.0366 | 0.6645 | 1 |
Brugia malayi | dihydrofolate reductase family protein | 0.0051 | 0.0716 | 0.0716 |
Brugia malayi | WGR domain containing protein | 0.0098 | 0.1589 | 0.1589 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0473 | 0.0473 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0316 | 0.5703 | 0.5703 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.0116 | 0.0902 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0316 | 0.5703 | 0.5703 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0134 | 0.0134 |
Loa Loa (eye worm) | carboxylesterase | 0.0013 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0316 | 0.5703 | 0.5703 |
Loa Loa (eye worm) | poly(ADP-ribose) polymerase | 0.0059 | 0.0863 | 0.0863 |
Schistosoma mansoni | carbonic anhydrase | 0.0117 | 0.1959 | 0.1959 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1589 | 0.1589 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0134 | 0.0134 |
Schistosoma mansoni | ets-related | 0.0258 | 0.4606 | 0.4606 |
Brugia malayi | WGR domain containing protein | 0.0098 | 0.1589 | 0.1589 |
Chlamydia trachomatis | bifunctional 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase/dihydropteroate synthase | 0.0366 | 0.6645 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0366 | 0.6639 | 0.6639 |
Mycobacterium ulcerans | B12-dependent methionine synthase | 0.0135 | 0.2289 | 0.3444 |
Echinococcus granulosus | carbonic anhydrase | 0.0117 | 0.1959 | 0.1959 |
Schistosoma mansoni | netrin receptor unc5 | 0.0014 | 0.0011 | 0.0011 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0072 | 0.1097 | 0.1097 |
Echinococcus granulosus | neuroligin | 0.0013 | 0.0001 | 0.0001 |
Onchocerca volvulus | Netrin receptor homolog | 0.0014 | 0.0011 | 0.0054 |
Mycobacterium leprae | Probable dihydropteroate synthase 1 FolP1 (DHPS 1) (dihydropteroate pyrophosphorylase 1) (dihydropteroate dipyrophosphorylase 1) | 0.0366 | 0.6645 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0134 | 0.0629 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0018 | 0.0094 | 0.0733 |
Leishmania major | carbonic anhydrase-like protein | 0.0316 | 0.5703 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0022 | 0.0164 | 0.0164 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0022 | 0.0164 | 0.0245 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0134 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0521 | 0.0521 |
Loa Loa (eye worm) | beta-lactamase | 0.0041 | 0.0521 | 0.0521 |
Brugia malayi | thymidylate synthase | 0.0126 | 0.2122 | 0.2122 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0098 | 0.1589 | 0.2636 |
Entamoeba histolytica | hypothetical protein | 0.0018 | 0.0094 | 0.0594 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0134 | 0.0134 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0022 | 0.0164 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0134 | 0.0134 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0014 | 0.0011 | 0.0011 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0013 | 0.0001 | 0.0001 |
Echinococcus multilocularis | carbonic anhydrase | 0.0117 | 0.1959 | 0.1959 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0098 | 0.1589 | 0.2636 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0134 | 0.0134 |
Onchocerca volvulus | 0.0126 | 0.2122 | 1 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0079 | 0.1246 | 0.1246 |
Loa Loa (eye worm) | fli-1 protein | 0.0258 | 0.4606 | 0.4606 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0018 | 0.0094 | 0.0733 |
Mycobacterium tuberculosis | Dihydropteroate synthase 2 FolP2 (DHPS 2) (dihydropteroate pyrophosphorylase 2) | 0.0135 | 0.2289 | 0.3444 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0134 | 0.0134 |
Schistosoma mansoni | DNA helicase recq1 | 0.002 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0134 | 0.0134 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0117 | 0.1959 | 0.1959 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0359 | 0.2789 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0134 | 0.0134 |
Echinococcus granulosus | poly adp ribose polymerase 2 | 0.0098 | 0.1589 | 0.1589 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0134 | 0.0134 |
Brugia malayi | Ets-domain containing protein | 0.0085 | 0.1348 | 0.1348 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0134 | 0.0134 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0134 | 0.0134 |
Brugia malayi | beta-lactamase | 0.0041 | 0.0521 | 0.0521 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0041 | 0.0521 | 0.0782 |
Mycobacterium ulcerans | dihydropteroate synthase 1 FolP1 | 0.0366 | 0.6645 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0134 | 0.0134 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0098 | 0.1589 | 0.1589 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0013 | 0.0001 | 0.0001 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0013 | 0.000000015121 | 0.000000015121 |
Brugia malayi | Heterochromatin protein 1 | 0.0082 | 0.1287 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0001 | 0.0001 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0316 | 0.5703 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0018 | 0.0094 | 0.0733 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0051 | 0.0716 | 0.0716 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0521 | 0.0782 |
Echinococcus multilocularis | poly (adp ribose) polymerase 2 | 0.0098 | 0.1589 | 0.1589 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0134 | 0.0134 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0079 | 0.1246 | 0.1246 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.0164 | 0.1271 |
Echinococcus multilocularis | Ankyrin | 0.0014 | 0.0014 | 0.0014 |
Onchocerca volvulus | 0.0036 | 0.0425 | 0.2 | |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0014 | 0.0011 | 0.0011 |
Schistosoma mansoni | hypothetical protein | 0.0366 | 0.6639 | 0.6639 |
Echinococcus granulosus | geminin | 0.0366 | 0.6639 | 0.6639 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0134 | 0.0134 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0271 | 0.4865 | 0.4865 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0521 | 0.0521 |
Trichomonas vaginalis | chromobox protein, putative | 0.0049 | 0.0676 | 0.5254 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0002 | 0.0002 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0177 | 0.309 | 0.465 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0117 | 0.1959 | 0.1959 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.002 | 0.0116 | 0.0116 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0521 | 0.0724 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0134 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1246 | 0.1246 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0022 | 0.0164 | 1 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0098 | 0.1589 | 0.2391 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0134 | 0.0134 |
Onchocerca volvulus | 0.0013 | 0.0001 | 0.0005 | |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0014 | 0.0011 | 0.0011 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0018 | 0.0094 | 0.0733 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0014 | 0.0014 |
Mycobacterium leprae | PROBABLE DIHYDROPTEROATE SYNTHASE 2 FOLP2 (DHPS 2) (Dihydropteroate pyrophosphorylase 2) | 0.0135 | 0.2289 | 0.2887 |
Echinococcus granulosus | carbonic anhydrase II | 0.0316 | 0.5703 | 0.5703 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0134 | 0.0134 |
Brugia malayi | Carboxylesterase family protein | 0.0013 | 0.0001 | 0.0001 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0134 | 0.0134 |
Entamoeba histolytica | poly(ADP-ribose) polymerase, putative | 0.0098 | 0.1589 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0134 | 0.0134 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0013 | 0.0001 | 0.0009 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0041 | 0.0521 | 0.0521 |
Echinococcus multilocularis | tankyrase | 0.0018 | 0.0094 | 0.0094 |
Echinococcus granulosus | poly ADP ribose polymerase 1 | 0.0098 | 0.1589 | 0.1589 |
Echinococcus granulosus | thymidylate synthase | 0.0126 | 0.2122 | 0.2122 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0134 | 0.0134 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0013 | 0.0001 | 0.0001 |
Echinococcus multilocularis | chromobox protein 1 | 0.0082 | 0.1287 | 0.1287 |
Echinococcus granulosus | acetylcholinesterase | 0.0079 | 0.1246 | 0.1246 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0013 | 0.0001 | 0.0001 |
Onchocerca volvulus | 0.0013 | 0.0001 | 0.0005 | |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0116 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0001 | 0.0001 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0117 | 0.1959 | 0.1959 |
Trypanosoma brucei | poly(adp-ribose) polymerase | 0.0098 | 0.1589 | 0.2636 |
Echinococcus granulosus | dihydrofolate reductase | 0.0051 | 0.0716 | 0.0716 |
Toxoplasma gondii | exonuclease III APE | 0.0022 | 0.0164 | 0.0246 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0126 | 0.2122 | 0.2614 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.0521 | 0.0782 |
Echinococcus multilocularis | geminin | 0.0366 | 0.6639 | 0.6639 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0041 | 0.0521 | 0.0782 |
Entamoeba histolytica | hypothetical protein | 0.0018 | 0.0094 | 0.0594 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0041 | 0.0521 | 0.0521 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0134 | 0.0134 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0038 | 0.0473 | 0.0473 |
Brugia malayi | chromobox protein homolog 3 | 0.0046 | 0.0611 | 0.0611 |
Entamoeba histolytica | hypothetical protein | 0.0018 | 0.0094 | 0.0594 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0177 | 0.309 | 0.465 |
Schistosoma mansoni | DNA helicase recq5 | 0.002 | 0.0116 | 0.0116 |
Onchocerca volvulus | Tankyrase homolog | 0.0018 | 0.0094 | 0.0445 |
Loa Loa (eye worm) | tnks protein | 0.0018 | 0.0097 | 0.0097 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0734 | 0.0734 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0521 | 0.0521 |
Brugia malayi | Carboxylesterase family protein | 0.0013 | 0.0001 | 0.0001 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.006 | 0.0877 | 0.1363 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0014 | 0.0011 | 0.0011 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0018 | 0.0094 | 0.0733 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0177 | 0.309 | 0.465 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0013 | 0.0001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0134 | 0.0134 |
Trichomonas vaginalis | chromobox protein, putative | 0.0049 | 0.0676 | 0.5254 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0521 | 0.0784 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0134 | 0.0134 |
Entamoeba histolytica | zinc finger protein, putative | 0.0018 | 0.0094 | 0.0594 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0134 | 0.0134 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0046 | 0.0611 | 0.2879 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0011 | 0.0011 |
Echinococcus multilocularis | acetylcholinesterase | 0.0079 | 0.1246 | 0.1246 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0041 | 0.0521 | 0.4046 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0134 | 0.0134 |
Echinococcus multilocularis | neuroligin | 0.0013 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0611 | 0.0611 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0046 | 0.0611 | 0.4746 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0134 | 0.0134 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.002 | 0.0116 | 0.0175 |
Mycobacterium ulcerans | thymidylate synthase | 0.0126 | 0.2122 | 0.3192 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0116 | 0.0175 |
Brugia malayi | Ets-domain containing protein | 0.0085 | 0.1348 | 0.1348 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.002 | 0.0116 | 0.0116 |
Toxoplasma gondii | ABC1 family protein | 0.0041 | 0.0521 | 0.0784 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0359 | 0.2789 |
Mycobacterium leprae | Probable 5-methyltetrahydrofolate--homocystein methyltransferase MetH (Methionine synthase, vitamin-B12 dependent isozyme) (MS) | 0.0135 | 0.2289 | 0.2887 |
Entamoeba histolytica | recQ family helicase, putative | 0.002 | 0.0116 | 0.0731 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.002 | 0.0116 | 0.0116 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0022 | 0.0164 | 0.0085 |
Toxoplasma gondii | hypothetical protein | 0.0117 | 0.1959 | 0.2948 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.002 | 0.0116 | 0.0116 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0041 | 0.0521 | 0.4046 |
Mycobacterium tuberculosis | Dihydropteroate synthase 1 FolP (DHPS 1) (dihydropteroate pyrophosphorylase 1) (dihydropteroate diphosphorylase 1) | 0.0366 | 0.6645 | 1 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0051 | 0.0716 | 0.1076 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0521 | 0.0724 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0085 | 0.1348 | 0.1348 |
Echinococcus granulosus | chromobox protein 1 | 0.0082 | 0.1287 | 0.1287 |
Brugia malayi | Carboxylesterase family protein | 0.0079 | 0.1246 | 0.1246 |
Echinococcus granulosus | bloom syndrome protein | 0.002 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0134 | 0.0134 |
Echinococcus granulosus | carboxylesterase 5A | 0.0079 | 0.1246 | 0.1246 |
Trichomonas vaginalis | chromobox protein, putative | 0.0082 | 0.1287 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0134 | 0.0134 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0013 | 0.0001 | 0.0001 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0316 | 0.5703 | 1 |
Brugia malayi | Bloom's syndrome protein homolog | 0.002 | 0.0116 | 0.0116 |
Trichomonas vaginalis | esterase, putative | 0.0041 | 0.0521 | 0.4046 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.002 | 0.0116 | 0.0902 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0014 | 0.0011 | 0.0011 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0316 | 0.5703 | 0.5703 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0134 | 0.0134 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0134 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0001 | 0.0001 |
Echinococcus multilocularis | poly (ADP ribose) polymerase 1 | 0.0098 | 0.1589 | 0.1589 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 79.4328 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | ChEMBL. | No reference |
Potency (functional) | 100 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.