Detailed information for compound 1185216

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 7754.96 | Formula: C315H490N53Na9O142S8
  • H donors: 73 H acceptors: 95 LogP: -21.93 Rotable bonds: 317
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)Cc1ccccc1)Cc1c[nH]c2c1cccc2)CC(=O)N)Cc1c[nH]c2c1cccc2)CC(C)C)CO)C)Cc1c[nH]c2c1cccc2)CC(C)C)CC(=O)O)CC(C)C)CCC(=O)O)CC(C)C)CC(C)C)CCC(=O)O)CCC(=O)N)CCC(=O)O)CC(=O)N)CC(C)C)CCC(=O)O)CCC(=O)N)CCC(=O)N)CC(=O)N)CCC(=O)N)CO)CCC(=O)O)CCC(=O)O)[C@H](CC)C)CC(C)C)CO)Cc1cnc[nH]1)[C@H](CC)C)CC(C)C)NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)C(NC(=O)C)CSC1CC(=O)N(C1=O)CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)N[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1OC)OC)COS(=O)(=O)[O-])O[C@H]1[C@H](OC)[C@@H](OC)[C@@H](O[C@]1(CC)C(=O)[O-])O[C@@H]1[C@@H](CS(=O)(=O)[O-])O[C@@H]([C@@H]([C@H]1CS(=O)(=O)[O-])CS(=O)(=O)[O-])O[C@@H]1[C@@H](O[C@H]([C@@H]([C@H]1OC)OC)O[C@H]1[C@H](COS(=O)(=O)[O-])O[C@H]([C@H]([C@H]1OS(=O)(=O)[O-])OS(=O)(=O)[O-])OC)C(=O)[O-])Cc1ccc(cc1)O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
  • InChi: 1S/C315H499N53O142S8.9Na/c1-32-179(20)253(304(434)341-208(66-76-251(396)397)276(406)336-207(65-75-250(394)395)281(411)361-228(161-370)299(429)340-202(60-70-239(319)379)277(407)355-223(151-240(320)380)292(422)337-201(59-69-238(318)378)274(404)332-199(57-67-236(316)376)272(402)334-205(63-73-248(390)391)279(409)344-212(139-173(8)9)287(417)356-224(152-241(321)381)293(423)339-203(61-71-246(386)387)275(405)333-200(58-68-237(317)377)273(403)335-204(62-72-247(388)389)278(408)343-211(138-172(6)7)284(414)346-210(137-171(4)5)283(413)338-206(64-74-249(392)393)280(410)345-213(140-174(10)11)288(418)358-226(154-252(398)399)295(425)347-214(141-175(12)13)285(415)352-219(147-186-156-326-196-50-41-38-47-191(186)196)282(412)330-181(22)271(401)360-227(160-369)300(430)348-215(142-176(14)15)286(416)353-221(149-188-158-328-198-52-43-40-49-193(188)198)290(420)357-225(153-242(322)382)294(424)354-220(148-187-157-327-197-51-42-39-48-192(187)197)289(419)342-209(270(323)400)145-184-45-36-35-37-46-184)365-296(426)216(143-177(16)17)349-301(431)229(162-371)362-291(421)222(150-189-159-324-170-329-189)359-305(435)254(180(21)33-2)366-297(427)217(144-178(18)19)350-302(432)230(163-372)363-306(436)255(182(23)373)367-298(428)218(146-185-53-55-190(375)56-54-185)351-303(433)231(331-183(24)374)166-511-235-155-245(385)368(307(235)437)80-77-243(383)325-79-84-473-88-92-477-96-100-481-104-108-485-112-116-489-120-124-492-126-128-494-130-132-496-134-136-497-135-133-495-131-129-493-127-125-491-122-118-487-114-110-483-106-102-479-98-94-475-90-86-471-82-44-81-470-85-89-474-93-97-478-101-105-482-109-113-486-117-121-490-123-119-488-115-111-484-107-103-480-99-95-476-91-87-472-83-78-244(384)364-256-260(464-26)258(463-25)232(164-498-515(451,452)453)500-310(256)507-269-264(466-28)267(468-30)313(508-315(269,34-3)314(440)441)503-257-194(167-512(442,443)444)195(168-513(445,446)447)309(502-234(257)169-514(448,449)450)505-262-261(465-27)266(467-29)312(506-265(262)308(438)439)504-259-233(165-499-516(454,455)456)501-311(469-31)268(510-518(460,461)462)263(259)509-517(457,458)459;;;;;;;;;/h35-43,45-56,156-159,170-182,194-195,199-235,253-269,309-313,326-328,369-373,375H,32-34,44,57-155,160-169H2,1-31H3,(H2,316,376)(H2,317,377)(H2,318,378)(H2,319,379)(H2,320,380)(H2,321,381)(H2,322,382)(H2,323,400)(H,324,329)(H,325,383)(H,330,412)(H,331,374)(H,332,404)(H,333,405)(H,334,402)(H,335,403)(H,336,406)(H,337,422)(H,338,413)(H,339,423)(H,340,429)(H,341,434)(H,342,419)(H,343,408)(H,344,409)(H,345,410)(H,346,414)(H,347,425)(H,348,430)(H,349,431)(H,350,432)(H,351,433)(H,352,415)(H,353,416)(H,354,424)(H,355,407)(H,356,417)(H,357,420)(H,358,418)(H,359,435)(H,360,401)(H,361,411)(H,362,421)(H,363,436)(H,364,384)(H,365,426)(H,366,427)(H,367,428)(H,386,387)(H,388,389)(H,390,391)(H,392,393)(H,394,395)(H,396,397)(H,398,399)(H,438,439)(H,440,441)(H,442,443,444)(H,445,446,447)(H,448,449,450)(H,451,452,453)(H,454,455,456)(H,457,458,459)(H,460,461,462);;;;;;;;;/q;9*+1/p-9/t179-,180-,181-,182+,194+,195+,199-,200-,201-,202-,203-,204-,205-,206-,207-,208-,209-,210-,211-,212-,213-,214-,215-,216-,217-,218-,219-,220-,221-,222-,223-,224-,225-,226-,227-,228-,229-,230-,231?,232-,233-,234+,235?,253-,254-,255-,256-,257-,258-,259-,260-,261-,262-,263-,264+,265+,266+,267+,268-,269-,309+,310+,311+,312+,313+,315-;;;;;;;;;/m0........./s1
  • InChiKey: MEQOHNWIQQJMHI-UQAOXLMNSA-E  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Bos taurus Coagulation factor X Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0018 0.0011 0.0008
Onchocerca volvulus Protein ultraspiracle homolog 0.0042 0.0162 0.0294
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0042 0.0162 0.0176
Schistosoma mansoni hypothetical protein 0.0926 0.5785 0.6445
Schistosoma mansoni inositol transporter 0.0042 0.0162 0.0176
Echinococcus granulosus mitogen activated protein kinase 0.0056 0.0252 0.0277
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Loa Loa (eye worm) bromodomain containing protein 0.0028 0.0076 0.0156
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0065 0.0061
Mycobacterium ulcerans beta-lactamase 0.0073 0.0362 0.1733
Echinococcus granulosus zinc finger protein 0.0031 0.0091 0.0097
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0048 0.0201 0.0492
Brugia malayi Nuclear hormone receptor E75 0.002 0.0021 0.0038
Loa Loa (eye worm) hypothetical protein 0.0378 0.2303 0.4938
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0252 0.0483
Schistosoma mansoni smad 0.0023 0.0041 0.0042
Echinococcus multilocularis snurportin 1 0.0615 0.381 0.3808
Schistosoma mansoni nuclear receptor 0.002 0.0021 0.002
Brugia malayi photoreceptor-specific nuclear receptor 0.0042 0.0162 0.034
Toxoplasma gondii target of rapamycin (TOR), putative 0.0036 0.0123 0.1847
Trypanosoma brucei ISWI complex protein 0.0018 0.0011 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0118 0.0649 0.1611
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0138 0.0246
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0043 0.0181
Trichomonas vaginalis ran, putative 0.0042 0.0166 0.0303
Schistosoma mansoni nuclear hormone receptor 0.002 0.0021 0.002
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0093 0.0488 0.0978
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0049 0.0211 0.0445
Schistosoma mansoni hypothetical protein 0.0048 0.0199 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.006 0.0083
Brugia malayi Bromodomain containing protein 0.0096 0.0506 0.1078
Trypanosoma brucei protein kinase, putative 0.0056 0.0252 0.0619
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0048 0.0201 0.0492
Toxoplasma gondii hypothetical protein 0.0104 0.0559 0.8616
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0123 0.0213
Brugia malayi PHD-finger family protein 0.0037 0.0131 0.0272
Mycobacterium tuberculosis Probable oxidoreductase 0.0076 0.0377 0.1313
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.002 0.0025 0.0514
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3805 0.7915
Plasmodium falciparum FAD-dependent monooxygenase, putative 0.0076 0.0377 0.8917
Loa Loa (eye worm) hypothetical protein 0.0489 0.3006 0.6448
Mycobacterium ulcerans aldehyde dehydrogenase 0.0118 0.0649 0.3125
Brugia malayi MAP kinase sur-1 0.0056 0.0252 0.0533
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0021 0.0411
Echinococcus granulosus citrate lyase subunit beta protein 0.005 0.0214 0.0235
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0043 0.0085
Toxoplasma gondii FAD binding domain-containing protein 0.0076 0.0377 0.5797
Entamoeba histolytica hypothetical protein 0.0047 0.0193 0.0456
Echinococcus granulosus Smad4 0.0051 0.0221 0.0242
Schistosoma mansoni nuclear receptor 0.002 0.0021 0.002
Echinococcus granulosus PHD finger protein rhinoceros 0.0064 0.0302 0.0332
Brugia malayi glutathione reductase 0.0037 0.0129 0.0268
Brugia malayi hypothetical protein 0.0231 0.1366 0.2926
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0042 0.0162 0.0294
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0615 0.3805 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0021 0.0338
Leishmania major importin beta-1 subunit, putative 0.0047 0.0193 0.0474
Brugia malayi ecdysteroid receptor 0.0042 0.0162 0.034
Echinococcus granulosus calpain 7 C02 family 0.0019 0.0015 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0056 0.0252 0.0277
Schistosoma mansoni steroid hormone receptor ad4bp 0.0042 0.0162 0.0176
Brugia malayi SH2 domain containing protein 0.0352 0.2137 0.4582
Loa Loa (eye worm) hypothetical protein 0.0045 0.0183 0.0386
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0042 0.0166 0.0405
Schistosoma mansoni hypothetical protein 0.0048 0.0199 0.0218
Echinococcus multilocularis PHD finger protein rhinoceros 0.0064 0.0302 0.0298
Echinococcus granulosus methyl CpG binding domain protein 2 0.002 0.0024 0.0022
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0093 0.0485 0.1689
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0159 0.0155
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0043 0.0099
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.012 0.1811
Loa Loa (eye worm) jmjC domain-containing protein 0.0021 0.0027 0.005
Trypanosoma cruzi trypanothione reductase, putative 0.0037 0.0129 0.0312
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0025 0.0088
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0118 0.0649 0.2256
Schistosoma mansoni protein phosphatase 2C 0.0021 0.0027 0.0026
Mycobacterium tuberculosis Probable oxidoreductase 0.0076 0.0377 0.1313
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0056 0.0252 0.0533
Brugia malayi nuclear hormone receptor 0.0042 0.0162 0.034
Echinococcus granulosus sodium:glucose cotransporter 2 0.0042 0.0162 0.0176
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0042 0.0162 0.0176
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.002 0.0021 0.0038
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.002 0.0021 0.0018
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0252 0.0483
Plasmodium vivax SET domain protein, putative 0.0097 0.0514 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0362 0.077
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0292 0.0322
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0015 0.0029
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.012 0.2785
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0042 0.0162 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0042 0.0162 0.034
Brugia malayi Pre-SET motif family protein 0.0097 0.0514 0.1097
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0292 0.0322
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0042 0.0162 0.0158
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0024 0.0022
Leishmania major UDP-galactopyranose mutase 0.002 0.0025 0.0054
Trypanosoma brucei unspecified product 0.0029 0.0077 0.0184
Echinococcus granulosus high affinity choline transporter 1 0.0378 0.2303 0.2563
Loa Loa (eye worm) hypothetical protein 0.006 0.028 0.0593
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0043 0.015
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0166 0.0162
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0052 0.0226 0.0248
Onchocerca volvulus 0.0042 0.0162 0.0293
Trypanosoma brucei unspecified product 0.0029 0.0077 0.0184
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0043 0.0181
Trypanosoma cruzi Monooxygenase, putative 0.0076 0.0377 0.0934
Echinococcus multilocularis zinc finger protein 0.0031 0.0091 0.0087
Mycobacterium ulcerans monoamine oxidase 0.002 0.0025 0.0094
Brugia malayi MH2 domain containing protein 0.0749 0.466 1
Loa Loa (eye worm) hypothetical protein 0.0311 0.1871 0.4011
Loa Loa (eye worm) MH1 domain-containing protein 0.0051 0.0221 0.0466
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0201 0.0376
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0091 0.0474 0.1175
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0042 0.0162 0.0176
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0362 0.1893
Schistosoma mansoni calpain (C02 family) 0.0019 0.0015 0.0013
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0043 0.0085
Brugia malayi CHE-14 protein 0.0049 0.0211 0.0445
Echinococcus multilocularis lysine specific demethylase 6a 0.0021 0.0027 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0097 0.0514 0.0569
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0042 0.0162 0.0176
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0362 0.126
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0043 0.0099
Schistosoma mansoni monoxygenase 0.0076 0.0377 0.0417
Loa Loa (eye worm) hypothetical protein 0.0049 0.0211 0.0445
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0046
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0015 0.0029
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0362 0.126
Brugia malayi acetyltransferase, GNAT family protein 0.031 0.1868 0.4004
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0043 0.0085
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0123 0.0213
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0021 0.0018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0042 0.0162 0.034
Schistosoma mansoni sodium/solute symporter 0.0042 0.0162 0.0176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0094 0.0153
Schistosoma mansoni patched 1 0.0049 0.0211 0.0231
Brugia malayi MH1 domain containing protein 0.0051 0.0221 0.0466
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0048 0.0201 0.0423
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0162 0.0176
Loa Loa (eye worm) hypothetical protein 0.0055 0.0249 0.0527
Plasmodium vivax calpain, putative 0.0019 0.0015 0.0226
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0159 0.0388
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0123 0.0213
Giardia lamblia Fructose-bisphosphate aldolase 0.0615 0.3805 1
Echinococcus granulosus expressed conserved protein 0.0085 0.0434 0.048
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0043 0.0181
Brugia malayi steroid hormone receptor 0.0042 0.0162 0.034
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0042 0.0166 0.3871
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0077 0.0184
Loa Loa (eye worm) hypothetical protein 0.0042 0.0162 0.034
Echinococcus granulosus SAM and MBT domain containing protein 0.0152 0.0861 0.0955
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0362 0.0714
Brugia malayi AF-10 protein 0.0021 0.0029 0.0054
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0021 0.0043
Schistosoma mansoni Smad4 0.0023 0.0041 0.0042
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0083 0.0426 0.1483
Loa Loa (eye worm) hypothetical protein 0.0044 0.0176 0.037
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0021 0.0018
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Loa Loa (eye worm) hypothetical protein 0.0049 0.0205 0.0432
Brugia malayi jmjC domain containing protein 0.0209 0.1225 0.2622
Echinococcus multilocularis polycomb protein SCMH1 0.0152 0.0861 0.0857
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0048 0.0201 0.022
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0646 0.4008 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0101 0.0166
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0006 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.007
Mycobacterium leprae possibleputative FAD-linked oxidoreductase 0.0076 0.0377 0.1978
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0042 0.0162 0.034
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0043 0.0181
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0056 0.0252 0.0619
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0083 0.0424 0.0468
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3805 0.7915
Trichomonas vaginalis PIKK family atypical protein kinase 0.0041 0.0156 0.0283
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0042 0.0162 0.0158
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0078 0.0391 0.0388
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.002 0.0025 0.0422
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.002 0.0021 0.002
Loa Loa (eye worm) MH1 domain-containing protein 0.0023 0.0041 0.0081
Brugia malayi MH2 domain containing protein 0.0051 0.0221 0.0466
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.006 0.0083
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0052 0.0226 0.0248
Echinococcus granulosus lysine specific demethylase 5A 0.0079 0.0401 0.0443
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.005
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0118 0.0649 0.0645
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0019 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0023 0.0043 0.0084
Loa Loa (eye worm) hypothetical protein 0.0083 0.0424 0.0902
Brugia malayi beta-lactamase family protein 0.0073 0.0362 0.077
Loa Loa (eye worm) hypothetical protein 0.0042 0.0162 0.034
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Brugia malayi Bromodomain containing protein 0.0053 0.0231 0.0488
Mycobacterium leprae Probable lipase LipE 0.0073 0.0362 0.1893
Schistosoma mansoni hypothetical protein 0.0048 0.0199 0.0218
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0159 0.0173
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.005 0.0214 0.1014
Loa Loa (eye worm) hypothetical protein 0.0073 0.0362 0.077
Schistosoma mansoni hypothetical protein 0.0179 0.1036 0.1151
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0241 0.1426 0.1423
Echinococcus multilocularis mothers against decapentaplegic 6 0.0023 0.0041 0.0038
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0345 0.0341
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0022 0.0036 0.007
Schistosoma mansoni amine oxidase 0.002 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0117 0.0641 0.071
Mycobacterium ulcerans hypothetical protein 0.0076 0.0377 0.1807
Schistosoma mansoni Smad4 0.0023 0.0041 0.0042
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0262 0.1564 0.3351
Toxoplasma gondii PHD-finger domain-containing protein 0.0064 0.0302 0.4622
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0362 0.0714
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0292 0.0322
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0602 0.3723 0.4146
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3805 0.7915
Schistosoma mansoni sex comb on midleg homolog 0.0152 0.0861 0.0955
Loa Loa (eye worm) hypothetical protein 0.0179 0.1036 0.2218
Mycobacterium ulcerans hypothetical protein 0.0076 0.0377 0.1807
Giardia lamblia PHD finger protein 15 0.0064 0.0302 0.0742
Brugia malayi amine oxidase, flavin-containing family protein 0.002 0.0025 0.0046
Mycobacterium tuberculosis Conserved protein 0.0073 0.0362 0.126
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0043 0.0059
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3805 0.7915
Onchocerca volvulus 0.0152 0.0861 0.1756
Plasmodium vivax glutathione reductase, putative 0.0037 0.0129 0.2445
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0166 0.0405
Echinococcus granulosus Niemann Pick C1 protein 0.0165 0.0944 0.1048
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0362 0.0714
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0097 0.0514 0.792
Echinococcus granulosus histone acetyltransferase KAT2B 0.0093 0.0488 0.0541
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.009 0.0467 0.0516
Loa Loa (eye worm) DR-78 0.002 0.0021 0.0038
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0306 0.1842 0.4591
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0061 0.0083
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0093 0.0488 0.7519
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0263 0.0647
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0152 0.0861 0.0955
Toxoplasma gondii exonuclease III APE 0.002 0.0021 0.0267
Loa Loa (eye worm) phosphatidylinositol 3 0.0048 0.0201 0.0423
Schistosoma mansoni zinc finger protein 0.0031 0.0091 0.0097
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0015 0.0029
Echinococcus multilocularis protein patched 0.0049 0.0211 0.0207
Mycobacterium ulcerans membrane-associated oxidoreductase 0.0076 0.0377 0.1807
Schistosoma mansoni nuclear hormone receptor 0.002 0.0021 0.002
Mycobacterium ulcerans FAD-linked oxidoreductase 0.0076 0.0377 0.1807
Brugia malayi SWIRM domain containing protein 0.002 0.0025 0.0046
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0241 0.1426 0.3055
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0268 0.1601 0.5569
Schistosoma mansoni jumonji/arid domain-containing protein 0.0079 0.0401 0.0443
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0468 0.2874 1
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0021 0.0029 0.0062
Plasmodium vivax importin-beta 2, putative 0.0058 0.0263 0.5073
Trypanosoma brucei antigen, putative 0.0019 0.0015 0.0029
Plasmodium vivax thioredoxin reductase, putative 0.0037 0.0129 0.2445
Leishmania major hypothetical protein, conserved 0.0435 0.266 0.6634
Brugia malayi nuclear hormone receptor 0.002 0.0021 0.0038
Toxoplasma gondii ABC1 family protein 0.0073 0.0362 0.5561
Onchocerca volvulus 0.002 0.0025 0.0008
Loa Loa (eye worm) hypothetical protein 0.0073 0.0362 0.077
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0162 0.0176
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0362 0.0896
Brugia malayi hypothetical protein 0.0022 0.0036 0.007
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0048 0.0201 0.022
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0241 0.1426 0.1586
Echinococcus multilocularis thioredoxin glutathione reductase 0.0037 0.0132 0.0128
Loa Loa (eye worm) transcription factor SMAD2 0.0749 0.466 1
Brugia malayi RNA binding protein 0.0062 0.0292 0.062
Loa Loa (eye worm) hypothetical protein 0.0042 0.0162 0.034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0117 0.0642 0.0712
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0115 0.0629 0.1607
Trypanosoma brucei DNA polymerase eta, putative 0.0066 0.0316 0.0781
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0021 0.0027 0.0058
Mycobacterium ulcerans aldehyde dehydrogenase 0.0118 0.0649 0.3125
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0015 0.0029
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0093 0.0485 0.1689
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0362 0.126
Loa Loa (eye worm) Smad1 0.0051 0.0221 0.0466
Echinococcus multilocularis mothers against decapentaplegic 2 0.0023 0.0041 0.0038
Schistosoma mansoni aldehyde dehydrogenase 0.0118 0.0649 0.0719
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Echinococcus granulosus jumonji domain containing 1A 0.0021 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0066 0.0316 0.0671
Loa Loa (eye worm) hypothetical protein 0.0231 0.1366 0.2926
Loa Loa (eye worm) nuclear hormone receptor 0.002 0.0021 0.0038
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0042 0.0166 0.2516
Giardia lamblia Kinase, CMGC MAPK 0.0056 0.0252 0.061
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0036 0.0037
Echinococcus granulosus lysine specific histone demethylase 1A 0.002 0.0025 0.0024
Trypanosoma cruzi UDP-galactopyranose mutase 0.002 0.0025 0.0054
Schistosoma mansoni importin beta-1 0.0058 0.0263 0.0289
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0159 0.0155
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0015 0.0029
Chlamydia trachomatis monooxygenase 0.0076 0.0377 1
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.005 0.0214 0.0526
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.002 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.012 0.0292
Brugia malayi calpain family protein 1 0.005 0.0212 0.0447
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0015 0.0029
Mycobacterium tuberculosis Conserved hypothetical protein 0.034 0.2062 0.7173
Echinococcus granulosus calpain 0.0019 0.0015 0.0013
Brugia malayi hypothetical protein 0.002 0.0021 0.0038
Trichomonas vaginalis Citrate lyase beta chain, putative 0.005 0.0214 0.0405
Schistosoma mansoni ran 0.0042 0.0166 0.0181
Brugia malayi jmjC domain containing protein 0.0021 0.0027 0.005
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0196 0.0413
Loa Loa (eye worm) hypothetical protein 0.0042 0.0162 0.034
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0015 0.0029
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0201 0.0376
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0263 0.0259
Plasmodium vivax protoporphyrinogen oxidase, putative 0.002 0.0025 0.0422
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0042 0.0162 0.0176
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0029 0.0388
Loa Loa (eye worm) jmjC domain-containing protein 0.0079 0.0401 0.0854
Echinococcus granulosus tumor protein p63 0.0332 0.2005 0.2231
Brugia malayi nuclear hormone receptor family member nhr-6 0.002 0.0021 0.0038
Plasmodium vivax hypothetical protein, conserved 0.002 0.0025 0.0422
Schistosoma mansoni Mername-AA248 (C02 family) 0.0019 0.0015 0.0013
Brugia malayi ecdysone receptor 0.002 0.0021 0.0038
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0015 0.0029
Echinococcus granulosus smad 0.0051 0.0221 0.0242
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.012 0.0292
Loa Loa (eye worm) hypothetical protein 0.0042 0.0162 0.034
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0091 0.0474 0.1175
Mycobacterium ulcerans aldehyde dehydrogenase 0.0118 0.0649 0.3125
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0083 0.0424 0.042
Onchocerca volvulus Bile acid receptor homolog 0.0042 0.0162 0.0294
Onchocerca volvulus 0.0073 0.0362 0.0713
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0041 0.0042
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0377 0.7319
Brugia malayi Nuclear hormone receptor E75 0.002 0.0021 0.0038
Brugia malayi PHD-finger family protein 0.0023 0.0043 0.0084
Leishmania major hypothetical protein, conserved 0.0076 0.0377 0.0934
Treponema pallidum fructose-bisphosphate aldolase 0.0615 0.3805 1
Entamoeba histolytica Ran family GTPase 0.0042 0.0166 0.0383
Toxoplasma gondii PHD-finger domain-containing protein 0.0064 0.0302 0.4622
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0252 0.0619
Schistosoma mansoni hypothetical protein 0.0083 0.0424 0.0468
Schistosoma mansoni jumonji domain containing protein 0.0021 0.0027 0.0026
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0023 0.0047
Loa Loa (eye worm) hypothetical protein 0.0117 0.0642 0.1371
Loa Loa (eye worm) hypothetical protein 0.0073 0.0362 0.077
Mycobacterium ulcerans hypothetical protein 0.0076 0.0377 0.1807
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0064 0.0302 0.0332
Echinococcus granulosus geminin 0.0726 0.4513 0.5027
Schistosoma mansoni smad1 5 8 and 0.0051 0.0221 0.0242
Brugia malayi mbt repeat family protein 0.0152 0.0861 0.1841
Loa Loa (eye worm) hypothetical protein 0.0037 0.0129 0.0268
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0205 0.0224
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0193 0.0361
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0362 0.1733
Leishmania major GTP-binding protein, putative 0.0042 0.0166 0.0405
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0159 0.0334
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0209 0.1225 0.1361
Loa Loa (eye worm) nuclear receptor NHR-67 0.002 0.0021 0.0038
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0043 0.0059
Schistosoma mansoni coup transcription factor 0.0042 0.0162 0.0176
Leishmania major hypothetical protein, conserved 0.0073 0.0362 0.0896
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.012 0.1811
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0048 0.0201 0.0197
Brugia malayi Muscleblind-like protein 0.0489 0.3006 0.6448
Toxoplasma gondii thioredoxin reductase 0.0037 0.0129 0.1937
Echinococcus granulosus dna polymerase eta 0.0066 0.0316 0.0349
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.1366 0.1363
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0046
Echinococcus multilocularis protein MICAL 3 0.0076 0.0377 0.0374
Loa Loa (eye worm) hypothetical protein 0.0028 0.0076 0.0154
Mycobacterium ulcerans hypothetical protein 0.0073 0.0362 0.1733
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0139 0.0337
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0362 0.0359
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0021 0.0043
Leishmania major hypothetical protein, conserved 0.0018 0.0011 0.0018
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0021 0.0017
Plasmodium falciparum phd finger protein, putative 0.0064 0.0302 0.7109
Trypanosoma brucei trypanothione reductase 0.0037 0.0129 0.0312
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0021 0.0073
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0005
Brugia malayi nuclear receptor RXR 0.002 0.0021 0.0038
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0345 0.038
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0022 0.0036 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0162 0.034
Loa Loa (eye worm) hypothetical protein 0.0061 0.0281 0.0597
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0056 0.0252 0.0619
Mycobacterium ulcerans oxidoreductase 0.0076 0.0377 0.1807
Brugia malayi hypothetical protein 0.002 0.0021 0.0038
Brugia malayi mbt repeat family protein 0.0152 0.0861 0.1841
Loa Loa (eye worm) mbt repeat family protein 0.0152 0.0861 0.1841
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.005 0.0214 0.1014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Echinococcus granulosus FTZ F1 alpha 0.0042 0.0162 0.0176
Loa Loa (eye worm) hypothetical protein 0.0023 0.0041 0.0081
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0042 0.0162 0.0176
Brugia malayi Ets-domain containing protein 0.0071 0.0345 0.0733
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0159 0.0388
Echinococcus multilocularis Niemann Pick C1 protein 0.0115 0.0629 0.0626
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0078 0.012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0076 0.0116
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0362 0.04
Chlamydia trachomatis protoporphyrinogen oxidase 0.002 0.0025 0.0518
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0042 0.0162 0.034
Brugia malayi MH1 domain containing protein 0.0051 0.0221 0.0466
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0173 0.0994 0.2128
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0435 0.266 0.6634
Mycobacterium tuberculosis Possible oxidoreductase 0.0076 0.0377 0.1313
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0159 0.0388
Mycobacterium ulcerans FAD-dependent oxidoreductase 0.0076 0.0377 0.1807
Brugia malayi nuclear receptor NHR-67 0.002 0.0021 0.0038
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.007
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0041 0.0038
Brugia malayi jmjC domain containing protein 0.0021 0.0027 0.005
Brugia malayi RNA, U transporter 1 0.0164 0.0939 0.2008
Schistosoma mansoni ets-related 0.0214 0.1258 0.1399
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0292 0.062
Brugia malayi Steroid receptor seven-up type 2 0.0042 0.0162 0.034
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Loa Loa (eye worm) latrophilin receptor protein 2 0.0083 0.0424 0.0902
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3805 0.7915
Loa Loa (eye worm) calpain family protein 1 0.005 0.0212 0.0447
Loa Loa (eye worm) RNA binding protein 0.0062 0.0292 0.062
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0083 0.0426 0.1483
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0042 0.0162 0.034
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0162 0.0158
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0021 0.0072
Loa Loa (eye worm) hypothetical protein 0.0352 0.2137 0.4582
Loa Loa (eye worm) hepatopoietin HPO2 0.0035 0.012 0.0251
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0117 0.0642 0.0712
Loa Loa (eye worm) calpain family protein 1 0.0037 0.0129 0.0268
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0097 0.0514 0.0569
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0048 0.0201 0.0492
Echinococcus granulosus peregrin 0.0074 0.0367 0.0405
Loa Loa (eye worm) PHD-finger family protein 0.0064 0.0302 0.064
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0159 0.0744
Brugia malayi nuclear hormone receptor family member odr-7 0.002 0.0021 0.0038
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0021 0.0027 0.0058
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3805 0.7915
Schistosoma mansoni hypothetical protein 0.0085 0.0434 0.048
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0159 0.0173
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.007
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0021 0.0029 0.0597
Echinococcus granulosus lysine specific histone demethylase 1A 0.002 0.0025 0.0024
Echinococcus granulosus jumonji domain containing protein 0.0089 0.0461 0.0509
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0362 0.0896
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0042 0.0162 0.034
Echinococcus multilocularis protoporphyrinogen oxidase 0.002 0.0025 0.0022
Echinococcus multilocularis mitogen activated protein kinase 0.0056 0.0252 0.0248
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0083 0.0426 0.1483
Trichomonas vaginalis set domain proteins, putative 0.0771 0.4802 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0111 0.0601 0.1491
Echinococcus multilocularis muscleblind protein 0.0489 0.3006 0.3003
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0083 0.0424 0.0468
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0159 0.0334
Echinococcus granulosus sodium:myo inositol cotransporter 0.0042 0.0162 0.0176
Schistosoma mansoni retinoic acid receptor RXR 0.0042 0.0162 0.0176
Loa Loa (eye worm) hypothetical protein 0.0042 0.0162 0.034
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.002 0.0021 0.002
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0152 0.0861 0.1756
Leishmania major hypothetical protein, conserved 0.0021 0.0027 0.0058
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0015 0.0029
Echinococcus multilocularis peregrin 0.0074 0.0367 0.0364
Echinococcus multilocularis tumor protein p63 0.0332 0.2005 0.2002
Brugia malayi MH1 domain containing protein 0.0028 0.0076 0.0154
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0021 0.002
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0166 0.0181
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0166 0.0349
Loa Loa (eye worm) hypothetical protein 0.0073 0.0362 0.077
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0042 0.0165 0.0162
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0159 0.0289
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0362 0.04
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0042 0.0162 0.0158
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.012 0.2286
Brugia malayi beta-lactamase 0.0073 0.0362 0.077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0138 0.0246
Onchocerca volvulus 0.0023 0.0043 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0077 0.0184
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0061 0.0083
Mycobacterium ulcerans hypothetical protein 0.034 0.2062 1
Plasmodium falciparum importin beta, putative 0.0058 0.0263 0.618
Echinococcus granulosus thyroid hormone receptor alpha 0.002 0.0021 0.002
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0241 0.1426 0.1586
Leishmania major hypothetical protein, conserved 0.0076 0.0377 0.0934
Echinococcus multilocularis mitogen activated protein kinase 3 0.0056 0.0252 0.0248
Loa Loa (eye worm) hypothetical protein 0.0489 0.3006 0.6448
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0021 0.0027 0.0362
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.031 0.1868 0.1865
Brugia malayi conserved hypotetical protein 0.002 0.0021 0.0038
Mycobacterium ulcerans oxidoreductase 0.0076 0.0377 0.1807
Brugia malayi hypothetical protein 0.0257 0.153 0.3279
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0043 0.0181
Leishmania major hypothetical protein, conserved 0.0035 0.012 0.0292
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Echinococcus multilocularis GPCR, family 2 0.0083 0.0424 0.042
Brugia malayi nuclear receptor RXR 0.0022 0.0036 0.007
Echinococcus multilocularis lysine specific histone demethylase 1A 0.002 0.0025 0.0022
Mycobacterium tuberculosis Conserved hypothetical protein 0.0041 0.0159 0.0553
Mycobacterium tuberculosis Possible oxidoreductase 0.0076 0.0377 0.1313
Onchocerca volvulus 0.0073 0.0362 0.0713
Schistosoma mansoni transcription factor LCR-F1 0.0257 0.153 0.1702
Loa Loa (eye worm) MH2 domain-containing protein 0.0051 0.0221 0.0466
Echinococcus multilocularis smad 0.0051 0.0221 0.0217
Schistosoma mansoni Smad4 0.0051 0.0221 0.0242
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0006 0.0021
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0345 0.0733
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0263 0.4018
Leishmania major DNA polymerase eta, putative 0.0066 0.0316 0.0781
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0159 0.0388
Echinococcus granulosus polycomb protein SCMH1 0.0152 0.0861 0.0955
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0159 0.0744
Brugia malayi jmjC domain containing protein 0.0021 0.0027 0.005
Schistosoma mansoni thyroid hormone receptor 0.0042 0.0162 0.0176
Brugia malayi calpain family protein 1 0.005 0.0212 0.0447
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0042 0.0162 0.0176
Toxoplasma gondii FAD binding domain-containing protein 0.0076 0.0377 0.5797
Echinococcus granulosus mitogen activated protein kinase 3 0.0056 0.0252 0.0277
Brugia malayi Nuclear hormone receptor-like 1 0.0042 0.0162 0.034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0123 0.0213
Loa Loa (eye worm) hypothetical protein 0.0262 0.1564 0.3351
Plasmodium vivax hypothetical protein, conserved 0.002 0.0025 0.0422
Echinococcus multilocularis dna polymerase eta 0.0066 0.0316 0.0313
Loa Loa (eye worm) acetyltransferase 0.031 0.1868 0.4004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0042 0.0162 0.034
Schistosoma mansoni ap endonuclease 0.002 0.0021 0.0019
Schistosoma mansoni calpain-7 (C02 family) 0.0019 0.0015 0.0013
Trichomonas vaginalis esterase, putative 0.0073 0.0362 0.0714
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0241 0.1426 0.1586
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0042 0.0162 0.034
Mycobacterium tuberculosis Conserved protein 0.0073 0.0362 0.126
Echinococcus granulosus solute carrier family 5 0.0042 0.0162 0.0176
Brugia malayi MH2 domain containing protein 0.0051 0.0221 0.0466
Loa Loa (eye worm) hypothetical protein 0.0023 0.0043 0.0085
Brugia malayi jmjC domain containing protein 0.0079 0.0401 0.0854
Echinococcus multilocularis calpain 0.0019 0.0015 0.0012
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0021 0.0043
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0159 0.0365
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0083 0.0426 0.1483
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0117 0.0642 0.0639
Schistosoma mansoni hypothetical protein 0.0257 0.153 0.1702
Loa Loa (eye worm) MH2 domain-containing protein 0.0749 0.466 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0212 0.0447
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0362 0.04
Plasmodium vivax JmjC domain containing protein 0.0021 0.0027 0.0457
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0159 0.0173
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Schistosoma mansoni high-affinity choline transporter 0.0378 0.2303 0.2563
Echinococcus granulosus histone lysine methyltransferase setb 0.0117 0.0642 0.0712
Echinococcus multilocularis expressed conserved protein 0.0108 0.0585 0.0581
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0362 0.126
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0083 0.0424 0.0902
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0138 0.0246
Brugia malayi Pre-SET motif family protein 0.0678 0.4207 0.9027
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0048 0.0201 0.0475
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.1366 0.1519
Giardia lamblia DINP protein human, muc B family 0.0041 0.0159 0.0365
Echinococcus granulosus dna polymerase kappa 0.0041 0.0159 0.0173
Loa Loa (eye worm) jmjC domain-containing protein 0.0132 0.0734 0.1568
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0056 0.0252 0.0619
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0193 0.0361
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0241 0.1426 0.1586
Trypanosoma cruzi ISWI complex protein 0.0018 0.0011 0.0018
Echinococcus multilocularis 0.002 0.0025 0.0022
Schistosoma mansoni smad 0.0051 0.0221 0.0242
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.005 0.0214 0.0526
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0362 0.0714
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0015 0.0029
Echinococcus granulosus nuclear receptor nhr 48 0.002 0.0021 0.002
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0083 0.0426 0.2253
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3805 0.7915
Echinococcus granulosus JmjC domain containing protein 4 0.0021 0.0027 0.0026
Plasmodium falciparum thioredoxin reductase 0.0037 0.0129 0.2979
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0035 0.012 0.013
Schistosoma mansoni nuclear receptor nhr-48 0.002 0.0021 0.002
Loa Loa (eye worm) hypothetical protein 0.0064 0.0302 0.064
Brugia malayi Augmenter of liver regeneration 0.0035 0.012 0.0251
Echinococcus granulosus calpain A 0.0019 0.0015 0.0013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0015 0.0029
Mycobacterium tuberculosis Possible oxidoreductase 0.0076 0.0377 0.1313
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0173 0.0994 0.0991
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0029 0.049
Trypanosoma brucei hypothetical protein, conserved 0.0435 0.266 0.6634
Schistosoma mansoni hypothetical protein 0.0083 0.0424 0.0468
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0048 0.0201 0.0492
Echinococcus granulosus calpain 5 0.0019 0.0015 0.0013
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0042 0.0162 0.0176
Brugia malayi Latrophilin receptor protein 2 0.0083 0.0424 0.0902
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0015 0.0029
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0162 0.034
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0021 0.0043
Echinococcus granulosus Niemann Pick C1 protein 0.0115 0.0629 0.0697
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Entamoeba histolytica hypothetical protein 0.0257 0.153 0.3988
Brugia malayi PHD-finger family protein 0.0064 0.0302 0.064
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0091 0.0474 0.1175
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0042 0.0162 0.034
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0288 0.173 0.8385
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0166 0.0349
Echinococcus multilocularis JmjC domain containing protein 4 0.0021 0.0027 0.0023
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0252 0.0483
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0042 0.0162 0.0158
Schistosoma mansoni hypothetical protein 0.0083 0.0424 0.0468
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0093 0.0485 0.2585
Onchocerca volvulus 0.0047 0.0196 0.0365
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0193 0.0361
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0056 0.0252 0.0619
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0615 0.381 0.8175
Mycobacterium ulcerans oxidoreductase GMC-type 0.0076 0.0377 0.1807
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Schistosoma mansoni jumonji/arid domain-containing protein 0.0079 0.0401 0.0443
Brugia malayi Bromodomain containing protein 0.0074 0.0367 0.0781
Trichomonas vaginalis PIKK family atypical protein kinase 0.0048 0.0201 0.0376
Schistosoma mansoni hypothetical protein 0.0615 0.381 0.4243
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0093 0.0488 0.9493
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0042 0.0162 0.0158
Brugia malayi Thioredoxin reductase 0.0037 0.0129 0.0268
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0173 0.0994 0.1104
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.004 0.0091
Onchocerca volvulus 0.0049 0.0205 0.0383
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0004 0.0013
Brugia malayi latrophilin 2 splice variant baaae 0.0179 0.1036 0.2218
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0042 0.0162 0.034
Brugia malayi Importin beta-1 subunit 0.0058 0.0263 0.0556
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0056 0.0252 0.3846
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.03 0.1806 1
Echinococcus multilocularis SAM and MBT domain containing protein 0.0152 0.0861 0.0857
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0037 0.0129 0.0447
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0362 0.126
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0135 0.0328
Echinococcus multilocularis histone acetyltransferase MYST2 0.0173 0.0994 0.0991
Brugia malayi hypothetical protein 0.0022 0.0036 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0209 0.1225 0.1221
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3805 0.7915
Brugia malayi jmjC domain containing protein 0.0021 0.0027 0.005
Mycobacterium tuberculosis Conserved protein 0.005 0.0214 0.0746
Schistosoma mansoni hypothetical protein 0.0048 0.0199 0.0218
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Plasmodium vivax hypothetical protein, conserved 0.0064 0.0302 0.5836
Echinococcus granulosus phd:f box containing protein 0.0021 0.0027 0.0026
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Trypanosoma brucei Monooxygenase, putative 0.0076 0.0377 0.0934
Echinococcus multilocularis hypothetical protein 0.0019 0.0015 0.0012
Loa Loa (eye worm) nuclear receptor nhr-7B 0.002 0.0021 0.0038
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0118 0.0649 0.0719
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0362 0.0896
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0065 0.0068
Echinococcus granulosus protein MICAL 3 0.0076 0.0377 0.0417
Mycobacterium tuberculosis Conserved protein 0.0073 0.0362 0.126
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0043 0.015
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0091 0.0474 0.1175
Loa Loa (eye worm) hypothetical protein 0.0073 0.0362 0.077
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0065 0.0068
Echinococcus multilocularis FTZ F1 alpha 0.0042 0.0162 0.0158
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0015 0.0029
Brugia malayi Ets-domain containing protein 0.0071 0.0345 0.0733
Schistosoma mansoni hypothetical protein 0.0076 0.0377 0.0417
Echinococcus granulosus mothers against decapentaplegic 2 0.0023 0.0041 0.0042
Trypanosoma brucei kynurenine 3-monooxygenase, putative 0.0076 0.0377 0.0934
Schistosoma mansoni DNA polymerase eta 0.0066 0.0316 0.0349
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0042 0.0162 0.2448
Entamoeba histolytica acetyltransferase, GNAT family 0.0083 0.0423 0.1062
Echinococcus granulosus microtubule associated protein 2 0.1427 0.8974 1
Echinococcus granulosus histone acetyltransferase MYST2 0.0173 0.0994 0.1104
Echinococcus granulosus mothers against decapentaplegic 5 0.0051 0.0221 0.0242
Loa Loa (eye worm) hypothetical protein 0.0109 0.0591 0.1263
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0051 0.0053
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0288 0.173 0.8385
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0021 0.0029 0.0062
Schistosoma mansoni hypothetical protein 0.0726 0.4513 0.5027
Brugia malayi orphan nuclear receptor NR2E1 0.002 0.0021 0.0038
Echinococcus granulosus lysine specific demethylase 6a 0.0021 0.0027 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0211 0.0397
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0035 0.012 0.0117
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0042 0.0162 0.0176
Loa Loa (eye worm) hypothetical protein 0.0115 0.0629 0.1343
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0615 0.3805 1
Schistosoma mansoni hypothetical protein 0.0047 0.0196 0.0214
Onchocerca volvulus 0.0771 0.4802 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0299 0.1795 0.1998
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0021 0.0027 0.0362
Echinococcus multilocularis expressed conserved protein 0.0085 0.0434 0.043
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0036 0.007
Echinococcus granulosus mothers against decapentaplegic 6 0.0023 0.0041 0.0042
Echinococcus multilocularis high affinity choline transporter 1 0.0378 0.2303 0.23
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.006 0.0083
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0678 0.4207 0.9027
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.009 0.0467 0.0463
Mycobacterium ulcerans hypothetical protein 0.005 0.0214 0.1014
Loa Loa (eye worm) nuclear factor I 0.0028 0.0076 0.0154
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0241 0.1426 0.3055
Brugia malayi mothers against decapentaplegic homolog 3 0.0023 0.0041 0.0081
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0022 0.0036 0.0037
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.0135 0.2037
Brugia malayi hypothetical protein 0.002 0.0025 0.0046
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0043 0.0099
Echinococcus granulosus expressed conserved protein 0.0108 0.0585 0.0648
Echinococcus granulosus sterol regulatory element binding protein 0.0049 0.0211 0.0231
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0139 0.0337
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.002 0.0021 0.002
Leishmania major DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0042 0.0162 0.034
Schistosoma mansoni bromodomain containing protein 0.0082 0.0418 0.0462
Echinococcus granulosus TGF beta signal transducer SmadC 0.0051 0.0221 0.0242
Schistosoma mansoni hypothetical protein 0.0021 0.0029 0.0028
Trypanosoma cruzi UDP-galactopyranose mutase 0.002 0.0025 0.0054
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.002 0.0025 0.0334
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0025 0.0088
Loa Loa (eye worm) hypothetical protein 0.0031 0.0093 0.0191
Loa Loa (eye worm) hypothetical protein 0.0152 0.0861 0.1841
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0257 0.153 0.1527
Brugia malayi hypothetical protein 0.0311 0.1871 0.4011
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0362 0.0714
Loa Loa (eye worm) hypothetical protein 0.002 0.0021 0.0038
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0257 0.153 0.1702
Mycobacterium tuberculosis Probable oxidoreductase 0.0093 0.0485 0.1689
Mycobacterium ulcerans lipase LipD 0.0073 0.0362 0.1733
Schistosoma mansoni inositol transporter 0.0042 0.0162 0.0176
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0005
Echinococcus multilocularis calpain A 0.0052 0.0226 0.0223
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0019 0.0015 0.0029
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0193 0.0474
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0022 0.0036 0.0037
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0097 0.0514 0.0511
Loa Loa (eye worm) calpain 0.0019 0.0015 0.0025
Loa Loa (eye worm) hypothetical protein 0.0042 0.0162 0.034
Loa Loa (eye worm) steroid hormone receptor 0.0042 0.0162 0.034
Brugia malayi ImpB/MucB/SamB family protein 0.0066 0.0316 0.0671
Echinococcus multilocularis microtubule associated protein 2 0.1427 0.8974 0.8973
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0094 0.0492 0.0544
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0052 0.0226 0.0248
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0241 0.1426 0.1586
Schistosoma mansoni Lysine-specific histone demethylase 1 0.002 0.0025 0.0024
Echinococcus multilocularis jumonji domain containing 1A 0.0021 0.0027 0.0023
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0043 0.0101
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0056 0.0252 0.0619
Schistosoma mansoni phosphatidylserine receptor 0.0021 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0042 0.0162 0.0339
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0015 0.0029
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0306 0.1842 0.4591
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0263 0.0647
Echinococcus multilocularis geminin 0.0726 0.4513 0.4511
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0042 0.0166 0.3177
Schistosoma mansoni zinc finger protein 0.0018 0.0011 0.0008
Echinococcus multilocularis Smad4 0.0051 0.0221 0.0217
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0043 0.0101
Mycobacterium tuberculosis Probable dehydrogenase 0.0083 0.0426 0.1483
Echinococcus multilocularis sterol regulatory element binding protein 0.0049 0.0211 0.0207
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0139 0.0337
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0021 0.0037
Loa Loa (eye worm) PHD-finger family protein 0.0024 0.0051 0.0101
Echinococcus multilocularis jumonji domain containing protein 0.0089 0.0461 0.0457
Loa Loa (eye worm) beta-lactamase 0.0073 0.0362 0.077
Plasmodium falciparum glutathione reductase 0.0037 0.0129 0.2979
Brugia malayi F/Y-rich N-terminus family protein 0.0027 0.0066 0.0133
Mycobacterium ulcerans hypothetical protein 0.005 0.0214 0.1014
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0362 0.1733
Schistosoma mansoni amine oxidase 0.002 0.0025 0.0024
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0042 0.0165 0.018
Echinococcus multilocularis nuclear receptor nhr 48 0.002 0.0021 0.0018
Schistosoma mansoni zinc finger protein 0.002 0.0021 0.002
Schistosoma mansoni hypothetical protein 0.0083 0.0424 0.0468
Echinococcus multilocularis Niemann Pick C1 protein 0.0165 0.0944 0.094
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0159 0.0289
Giardia lamblia Histone acetyltransferase GCN5 0.0083 0.0423 0.1062
Brugia malayi Fli-1 protein 0.0214 0.1258 0.2695
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0042 0.0162 0.0158
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0362 0.077
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.005 0.0214 0.0746
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0123 0.0213
Entamoeba histolytica hypothetical protein 0.0257 0.153 0.3988
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0043 0.0181
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0078 0.012
Loa Loa (eye worm) hypothetical protein 0.0173 0.0994 0.2128
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.007
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0015 0.0029
Schistosoma mansoni RAR-like nuclear receptor 0.0042 0.0162 0.0176
Schistosoma mansoni sex comb on midleg homolog 0.0152 0.0861 0.0955
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0042 0.0166 0.0383
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0362 0.7021
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0262 0.1564 0.3351
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.005 0.0214 0.1014
Echinococcus multilocularis calpain family protein 1, d 0.0037 0.0129 0.0125
Brugia malayi GH02984p 0.0378 0.2303 0.4938
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0093 0.0488 0.7519
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0006 0.0056
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.005 0.0214 0.0526
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0061 0.0083
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.005 0.0212 0.0232
Loa Loa (eye worm) hypothetical protein 0.0058 0.0263 0.0558
Giardia lamblia GTOR 0.0048 0.0201 0.0475
Brugia malayi Sodium:solute symporter family protein 0.0042 0.0162 0.0339
Trypanosoma brucei unspecified product 0.0041 0.0159 0.0388
Schistosoma mansoni ran 0.0042 0.0166 0.0181
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0052 0.0226 0.0223
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0241 0.1426 0.1423
Loa Loa (eye worm) hypothetical protein 0.0083 0.0426 0.0907
Schistosoma mansoni survival motor neuron protein 0.0047 0.0196 0.0214
Mycobacterium ulcerans dehydrogenase 0.002 0.0025 0.0094
Schistosoma mansoni microtubule-associated protein tau 0.1427 0.8974 1
Echinococcus granulosus sodium:glucose cotransporter 0.0042 0.0162 0.0176
Loa Loa (eye worm) glutathione reductase 0.0037 0.0129 0.0268
Trypanosoma cruzi hypothetical protein, conserved 0.0435 0.266 0.6634
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0056 0.0252 0.0619
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.031 0.1868 0.2078
Brugia malayi nuclear receptor NHR-88 0.002 0.0021 0.0038
Loa Loa (eye worm) jmjC domain-containing protein 0.0021 0.0027 0.005
Loa Loa (eye worm) thioredoxin reductase 0.0037 0.0129 0.0268
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0292 0.062
Brugia malayi Calcitonin receptor-like protein seb-1 0.0262 0.1564 0.3351
Echinococcus multilocularis calpain 5 0.0019 0.0015 0.0012
Echinococcus multilocularis Nuclear hormone receptor HR96 0.002 0.0021 0.0018
Loa Loa (eye worm) hypothetical protein 0.0058 0.0263 0.0556
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0646 0.4008 1
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0292 0.0322
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0061 0.0083
Plasmodium falciparum protoporphyrinogen oxidase 0.002 0.0025 0.0514
Echinococcus multilocularis ecdysone induced protein 78C 0.0042 0.0162 0.0158
Loa Loa (eye worm) hypothetical protein 0.0023 0.0043 0.0085
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.002 0.0021 0.0018
Echinococcus granulosus calpain A 0.0052 0.0226 0.0248
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0042 0.0162 0.034
Echinococcus multilocularis solute carrier family 5 0.0042 0.0162 0.0158
Loa Loa (eye worm) MH2 domain-containing protein 0.0023 0.0041 0.0081
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0042 0.0162 0.0176
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0362 0.077
Echinococcus multilocularis phd:f box containing protein 0.0021 0.0027 0.0023
Loa Loa (eye worm) hypothetical protein 0.0021 0.0027 0.005
Brugia malayi Smad1 0.0051 0.0221 0.0466
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0021 0.0027 0.0026
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0021 0.0029 0.0388
Echinococcus multilocularis lysine specific demethylase 5A 0.0077 0.0387 0.0384
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0162 0.034
Brugia malayi MH1 domain containing protein 0.0028 0.0076 0.0154
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0051 0.0221 0.0242
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0123 0.0213
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0083 0.0424 0.042
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0021 0.0027 0.0058
Plasmodium falciparum JmjC domain-containing protein, putative 0.0021 0.0027 0.0557
Echinococcus granulosus snurportin 1 0.0615 0.381 0.4243
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.012 0.0292
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.012 0.0292
Schistosoma mansoni jumonji domain containing protein 0.0166 0.0952 0.1057
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0042 0.0162 0.0176
Trypanosoma cruzi ISWI complex protein 0.0018 0.0011 0.0018
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0362 0.126
Schistosoma mansoni smad1 5 8 and 0.0051 0.0221 0.0242
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.03 0.1806 0.6283
Echinococcus multilocularis calpain 7 (C02 family) 0.0019 0.0015 0.0012
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0042 0.0162 0.034
Onchocerca volvulus Alhambra homolog 0.0064 0.0302 0.0586
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0042 0.0162 0.034
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.03 0.1806 0.8755
Entamoeba histolytica hypothetical protein 0.0257 0.153 0.3988
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0015 0.0029
Loa Loa (eye worm) hypothetical protein 0.0017 0.0006 0.0005
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0362 0.126
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0048 0.0201 0.0492
Echinococcus granulosus tar DNA binding protein 0.0062 0.0292 0.0322
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0077 0.0184
Echinococcus granulosus GPCR family 2 0.0083 0.0424 0.0468
Schistosoma mansoni myelin transcription factor 1 myt1 0.0173 0.0994 0.1104
Toxoplasma gondii aldehyde dehydrogenase 0.0118 0.0649 1
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0023 0.0041 0.0041
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0042 0.0162 0.0176
Echinococcus multilocularis thyroid hormone receptor alpha 0.0042 0.0162 0.0158
Schistosoma mansoni methyl-cpg binding protein mbd 0.002 0.0024 0.0022
Mycobacterium tuberculosis Probable reductase 0.0083 0.0426 0.1483
Echinococcus multilocularis methyl CpG binding domain protein 2 0.002 0.0024 0.002
Echinococcus granulosus thioredoxin glutathione reductase 0.0037 0.0132 0.0143
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0042 0.0162 0.0158
Onchocerca volvulus 0.0311 0.1871 0.3869
Brugia malayi calpain 7 0.0019 0.0015 0.0025
Plasmodium vivax FAD-dependent monooxygenase, putative 0.0076 0.0377 0.7319
Trichomonas vaginalis CMGC family protein kinase 0.0056 0.0252 0.0483
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0048 0.0201 0.0492
Brugia malayi MH2 domain containing protein 0.0023 0.0041 0.0081
Schistosoma mansoni ap endonuclease 0.002 0.0021 0.0019
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0078 0.0391 0.0432
Echinococcus granulosus ecdysone induced protein 78C 0.0042 0.0162 0.0176
Mycobacterium ulcerans oxidoreductase 0.002 0.0025 0.0094
Trichomonas vaginalis bromodomain-containing protein, putative 0.0093 0.0488 0.0978
Echinococcus granulosus muscleblind protein 0.0489 0.3006 0.3347
Loa Loa (eye worm) hypothetical protein 0.0042 0.0162 0.034
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0048 0.0201 0.0475
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0041 0.0159 0.0553
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0036 0.007
Loa Loa (eye worm) hypothetical protein 0.0022 0.0036 0.007
Schistosoma mansoni gabp alpha 0.0071 0.0345 0.038
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0015 0.0029
Schistosoma mansoni hypothetical protein 0.0064 0.0302 0.0332
Echinococcus multilocularis protein dispatched 1 0.0056 0.0255 0.0252
Loa Loa (eye worm) hypothetical protein 0.0023 0.0043 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0042 0.0162 0.034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0076 0.0116
Loa Loa (eye worm) MBCTL1 0.0173 0.0994 0.2128
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0021 0.002
Onchocerca volvulus 0.0042 0.0162 0.0294
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0292 0.0322
Echinococcus granulosus importin subunit beta 1 0.0058 0.0263 0.0289
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0602 0.3723 0.372
Brugia malayi beta-lactamase family protein 0.0073 0.0362 0.077
Wolbachia endosymbiont of Brugia malayi 2-polyprenyl-6-methoxyphenol 4-hydroxylase 0.0076 0.0377 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0066 0.0316 0.0781
Schistosoma mansoni phd/f-box containing protein 0.0021 0.0027 0.0026
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0123 0.0213
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0046
Schistosoma mansoni smad1 5 8 and 0.0051 0.0221 0.0242
Echinococcus granulosus ubiquinone biosynthesis monooxygenase COQ6 0.0076 0.0377 0.0417
Entamoeba histolytica hypothetical protein 0.0257 0.153 0.3988
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0138 0.0246
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0025 0.0514
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Brugia malayi TAR-binding protein 0.0062 0.0292 0.062
Onchocerca volvulus 0.0031 0.0093 0.0149
Mycobacterium ulcerans hypothetical protein 0.0023 0.0043 0.0181
Onchocerca volvulus 0.0073 0.0362 0.0713
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0043 0.0059
Loa Loa (eye worm) hypothetical protein 0.0076 0.0377 0.0803
Mycobacterium ulcerans protoporphyrinogen oxidase 0.002 0.0025 0.0094
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0042 0.0162 0.0158
Echinococcus multilocularis ubiquinone biosynthesis monooxygenase COQ6 0.0076 0.0377 0.0374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0078 0.012
Schistosoma mansoni nuclear hormone receptor 0.0042 0.0162 0.0176
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0292 0.062
Brugia malayi nuclear receptor NHR-88 0.0042 0.0162 0.034
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0292 0.0289
Echinococcus granulosus Nuclear hormone receptor HR96 0.002 0.0021 0.002
Echinococcus multilocularis citrate lyase subunit beta protein 0.005 0.0214 0.0211
Leishmania major mitochondrial DNA polymerase beta 0.0646 0.4008 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0042 0.0162 0.034
Schistosoma mansoni hypothetical protein 0.0726 0.4513 0.5027
Plasmodium falciparum histone acetyltransferase GCN5 0.0083 0.0423 1
Schistosoma mansoni calpain-7 (C02 family) 0.0019 0.0015 0.0013
Echinococcus granulosus Protein patched homolog 1 0.0049 0.0211 0.0231
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0138 0.0246
Schistosoma mansoni aldehyde dehydrogenase 0.0118 0.0649 0.0719
Brugia malayi tailless protein 0.002 0.0021 0.0038
Schistosoma mansoni hypothetical protein 0.0024 0.0051 0.0052
Leishmania major DNA polymerase eta, putative 0.0038 0.0135 0.0328
Schistosoma mansoni calpain C (C02 family) 0.0019 0.0015 0.0013
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0646 0.4008 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0043 0.0181
Onchocerca volvulus 0.0097 0.0514 0.1031
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0046
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0051 0.0221 0.0217
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0042 0.0166 0.0405
Echinococcus multilocularis muscleblind protein 1 0.0489 0.3006 0.3003
Brugia malayi Niemann-Pick C1 protein precursor 0.0115 0.0629 0.1343
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0159 0.0388
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0046
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0377 0.0934
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0021 0.0037
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0306 0.1842 0.4591
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0042 0.0162 0.034
Loa Loa (eye worm) jmjC domain-containing protein 0.0021 0.0027 0.005
Leishmania major trypanothione reductase 0.0037 0.0129 0.0312
Toxoplasma gondii histone lysine-specific demethylase 0.002 0.0025 0.0334
Loa Loa (eye worm) fli-1 protein 0.0214 0.1258 0.2695
Echinococcus multilocularis mothers against decapentaplegic 5 0.0051 0.0221 0.0217
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0159 0.0388

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 53 nM Inhibition of bovine coagulation factor 10a by spectrophotometry ChEMBL. 19805567
Inhibition (binding) Inhibition of bovine coagulation factor 10a by spectrophotometry ChEMBL. 19805567

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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