Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.362 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.362 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.362 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.362 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.362 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.362 | 1 |
Onchocerca volvulus | 0.0026 | 0.362 | 0.5 | |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0503 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.362 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.362 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.362 | 0.5 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.362 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.0503 | 0.5 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0503 | 0.139 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.362 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.362 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.362 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.362 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.0503 | 0.5 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.362 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.362 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.362 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.362 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.