Detailed information for compound 1186649

Basic information

Technical information
  • TDR Targets ID: 1186649
  • Name: 3-(2,3-dihydro-1H-inden-5-yl)-2-methyl-2-[4-( phenylmethyl)phenoxy]propanoic acid
  • MW: 386.483 | Formula: C26H26O3
  • H donors: 1 H acceptors: 2 LogP: 6.42 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C(Cc1ccc2c(c1)CCC2)(Oc1ccc(cc1)Cc1ccccc1)C
  • InChi: 1S/C26H26O3/c1-26(25(27)28,18-21-10-13-22-8-5-9-23(22)17-21)29-24-14-11-20(12-15-24)16-19-6-3-2-4-7-19/h2-4,6-7,10-15,17H,5,8-9,16,18H2,1H3,(H,27,28)
  • InChiKey: LQTZGTKMZQBXDA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-indan-5-yl-2-methyl-2-[4-(phenylmethyl)phenoxy]propanoic acid
  • 3-(5-indanyl)-2-methyl-2-[4-(phenylmethyl)phenoxy]propanoic acid
  • 2-[4-(benzyl)phenoxy]-3-indan-5-yl-2-methyl-propionic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0077 0.1783
Echinococcus granulosus isocitrate dehydrogenase NAD subunit 0.0018 0.0008 0.0006
Mycobacterium tuberculosis Possible penicillin-binding protein 0.049 0.113 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Schistosoma mansoni ap endonuclease 0.002 0.0013 0.0013
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0248 0.0554 0.0552
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.001 0.0008
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0074 0.0142 0.963
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0018 0.0041
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0021 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0018 0.0016
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0018 0.0445
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.001 0.0258
Toxoplasma gondii patched family protein 0.0025 0.0025 0.0454
Schistosoma mansoni Smad4 0.0049 0.0082 0.0082
Echinococcus granulosus geminin 0.1964 0.4639 0.4638
Loa Loa (eye worm) MH2 domain-containing protein 0.0049 0.0082 0.0209
Loa Loa (eye worm) hypothetical protein 0.0308 0.0698 0.182
Loa Loa (eye worm) isocitrate dehydrogenase 0.0151 0.0325 0.0844
Trypanosoma brucei hypothetical protein, conserved 0.0077 0.0147 0.3646
Echinococcus multilocularis Niemann Pick C1 protein 0.0417 0.0956 0.0954
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0105 0.2478
Echinococcus multilocularis sterol regulatory element binding protein 0.0179 0.039 0.0388
Brugia malayi Patched protein homolog 1 0.0025 0.0025 0.0059
Loa Loa (eye worm) hypothetical protein 0.0021 0.0015 0.0033
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0038 0.0054 0.1335
Brugia malayi hypothetical protein 0.0025 0.0025 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0048 0.0268
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0007 0.0165
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0077 0.0147 0.1249
Brugia malayi MH2 domain containing protein 0.0111 0.0228 0.059
Loa Loa (eye worm) oxidoreductase 0.0022 0.0017 0.0038
Brugia malayi jmjC domain containing protein 0.0019 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0151 0.0325 0.2834
Loa Loa (eye worm) hypothetical protein 0.0077 0.0147 0.0379
Toxoplasma gondii patched family protein 0.0025 0.0025 0.0454
Mycobacterium tuberculosis Probable reductase 0.0116 0.0242 0.2094
Schistosoma mansoni Smad4 0.0049 0.0082 0.0082
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0014 0.0032
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0021 0.0014 0.0012
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.001 0.008
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0031 0.0781
Echinococcus multilocularis mothers against decapentaplegic 5 0.0111 0.0228 0.0226
Echinococcus multilocularis mothers against decapentaplegic 2 0.0049 0.0082 0.008
Mycobacterium ulcerans esterase/lipase LipP 0.0077 0.0147 1
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0151 0.0325 0.8063
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0013 0.0048
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0017 0.0038
Leishmania major DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Schistosoma mansoni smad1 5 8 and 0.0111 0.0228 0.0228
Trichomonas vaginalis isocitrate dehydrogenase, putative 0.0018 0.0008 0.0036
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0077 0.0721
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0111 0.0228 0.0228
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0022 0.0017 0.025
Onchocerca volvulus Protein patched homolog 0.0025 0.0025 0.0045
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Loa Loa (eye worm) hypothetical protein 0.0022 0.0018 0.0041
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0248 0.0554 0.0552
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Loa Loa (eye worm) patched family protein 0.0025 0.0025 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0077 0.0075
Onchocerca volvulus 0.0025 0.0025 0.0045
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0646 0.1502 0.392
Loa Loa (eye worm) patched family protein 0.0025 0.0025 0.0059
Schistosoma mansoni hypothetical protein 0.0059 0.0105 0.0105
Echinococcus granulosus isocitrate dehydrogenase NAD 0.0018 0.0008 0.0006
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0147 0.0147
Schistosoma mansoni jumonji domain containing protein 0.0019 0.001 0.001
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0077 0.0435
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0054 0.0301
Echinococcus multilocularis lamin 0.0221 0.0491 0.0489
Loa Loa (eye worm) transcription factor SMAD2 0.1623 0.3828 1
Schistosoma mansoni ap endonuclease 0.002 0.0013 0.0013
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Onchocerca volvulus 0.0025 0.0025 0.0045
Schistosoma mansoni smad1 5 8 and 0.0111 0.0228 0.0228
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0012 0.0027
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0074 0.0142 0.963
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.009 0.0739
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0086 0.0707
Leishmania major hypothetical protein, conserved 0.0019 0.001 0.0244
Schistosoma mansoni hypothetical protein 0.0248 0.0554 0.0554
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.001 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0706
Loa Loa (eye worm) hypothetical protein 0.0056 0.0097 0.0248
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0147 0.3646
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0031 0.0029
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.001 0.0244
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Schistosoma mansoni Smad4 0.0111 0.0228 0.0228
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0071 0.0133 0.3291
Brugia malayi Flap endonuclease-1 0.0028 0.0031 0.0077
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0053
Brugia malayi hypothetical protein 0.0025 0.0025 0.0059
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.001 0.0008
Onchocerca volvulus 0.0025 0.0025 0.0045
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0007 0.0012
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0013 0.0011
Toxoplasma gondii aldehyde dehydrogenase 0.0071 0.0133 0.3178
Onchocerca volvulus 0.0221 0.0491 0.2617
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0127 0.0327
Brugia malayi MH2 domain containing protein 0.0111 0.0228 0.059
Plasmodium falciparum flap endonuclease 1 0.0028 0.0031 0.0626
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0007 0.0165
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Brugia malayi isocitrate dehydrogenase 0.0151 0.0325 0.0844
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0179 0.039 0.1014
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0031 0.0626
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Loa Loa (eye worm) hypothetical protein 0.0049 0.0082 0.0209
Mycobacterium tuberculosis Conserved protein 0.0077 0.0147 0.1249
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0004 0.0002
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0022 0.0017 0.0706
Echinococcus multilocularis isocitrate dehydrogenase (NAD+) 0.0018 0.0008 0.0006
Plasmodium vivax acetyl-CoA synthetase, putative 0.0022 0.0017 0.025
Onchocerca volvulus 0.0735 0.1714 0.9368
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0013 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0151 0.0325 0.0323
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0018 0.0445
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0025 0.0134
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.001 0.0094
Schistosoma mansoni phd/f-box containing protein 0.0019 0.001 0.001
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Echinococcus granulosus dna polymerase kappa 0.0022 0.0018 0.0016
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0013 0.032
Loa Loa (eye worm) hypothetical protein 0.0107 0.0218 0.0565
Brugia malayi Pre-SET motif family protein 0.0646 0.1502 0.392
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0063 0.1419
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0031 0.0781
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0018 0.0805
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0077 0.1783
Toxoplasma gondii ABC1 family protein 0.0077 0.0147 0.3539
Brugia malayi AF-10 protein 0.0019 0.001 0.0022
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0074 0.0142 0.963
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0165
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0062 0.0112 0.011
Leishmania major hypothetical protein, conserved 0.0184 0.0403 1
Schistosoma mansoni hypothetical protein 0.0172 0.0375 0.0375
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0142 0.0365
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0048 0.0268
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0007 0.0165
Echinococcus granulosus histone acetyltransferase KAT2B 0.0149 0.0319 0.0317
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0142 0.3517
Leishmania major phosphatidylinositol 3-kinase, putative 0.0016 0.0002 0.0053
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0077 0.0439
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.001 0.0244
Loa Loa (eye worm) hypothetical protein 0.0077 0.0147 0.0379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0054 0.0301
Schistosoma mansoni Isocitrate dehydrogenase [NAD] subunit gamma mitochondrial 0.0018 0.0008 0.0008
Brugia malayi Pax transcription factor protein 2 0.0505 0.1166 0.3043
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0018 0.0805
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0017 0.0411
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0107 0.0218 0.0216
Giardia lamblia GTOR 0.0047 0.0077 0.7129
Echinococcus granulosus tar DNA binding protein 0.0068 0.0127 0.0125
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0127 0.0127
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0706
Brugia malayi Probable isocitrate dehydrogenase 0.0018 0.0008 0.0016
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0093 0.0185 0.4499
Leishmania major hypothetical protein, conserved 0.0077 0.0147 0.3646
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0151 0.0325 0.0325
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0109 0.0225 0.0225
Brugia malayi Smad1 0.0111 0.0228 0.059
Mycobacterium tuberculosis Probable dehydrogenase 0.0116 0.0242 0.2094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0031 0.0168
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0013 0.0028
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0151 0.0325 0.803
Echinococcus granulosus intermediate filament protein 0.0221 0.0491 0.0489
Echinococcus multilocularis Smad4 0.0111 0.0228 0.0226
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.001 0.0258
Toxoplasma gondii thioredoxin reductase 0.0051 0.0086 0.2004
Echinococcus multilocularis protein patched 0.0179 0.039 0.0388
Brugia malayi Bromodomain containing protein 0.0077 0.0147 0.038
Loa Loa (eye worm) hypothetical protein 0.0417 0.0956 0.2494
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0417 0.0956 1
Loa Loa (eye worm) acetyltransferase 0.0156 0.0335 0.087
Mycobacterium ulcerans hypothetical protein 0.0074 0.0142 0.963
Plasmodium vivax acyl-CoA synthetase, putative 0.0056 0.0097 0.2278
Onchocerca volvulus Alhambra homolog 0.0059 0.0105 0.0487
Brugia malayi jmjC domain containing protein 0.0193 0.0424 0.1103
Loa Loa (eye worm) hypothetical protein 0.0074 0.0142 0.0365
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0151 0.0325 0.0323
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0022 0.0017 0.0088
Schistosoma mansoni hypothetical protein 0.0157 0.0338 0.0338
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0056 0.0097 0.0248
Trichomonas vaginalis glutathione reductase, putative 0.0018 0.0007 0.0026
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0071 0.0133 0.0131
Onchocerca volvulus 0.0505 0.1166 0.6346
Loa Loa (eye worm) jmjC domain-containing protein 0.0122 0.0254 0.0659
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0129 0.0273 0.2369
Echinococcus multilocularis PHD finger protein rhinoceros 0.0059 0.0105 0.0103
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0017 0.0312
Trypanosoma cruzi PAB1-binding protein , putative 0.0184 0.0403 1
Loa Loa (eye worm) MH2 domain-containing protein 0.1623 0.3828 1
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0056 0.0097 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0127 0.0127
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0165
Loa Loa (eye worm) patched family protein 0.0025 0.0025 0.0059
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0165
Echinococcus granulosus smad 0.0111 0.0228 0.0226
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0127 0.0127
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0054 0.0301
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0151 0.0325 0.8063
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0001 0.0034
Plasmodium vivax hypothetical protein, conserved 0.0077 0.0147 0.3539
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0248 0.0554 0.0552
Brugia malayi Thioredoxin reductase 0.0051 0.0086 0.0219
Toxoplasma gondii LsmAD domain-containing protein 0.0184 0.0403 1
Echinococcus multilocularis protein dispatched 1 0.0204 0.045 0.0448
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0077 0.0147 0.1249
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0147 0.0846
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0142 0.963
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0074 0.0142 0.1203
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0022 0.0017 0.0087
Schistosoma mansoni hypothetical protein 0.0248 0.0554 0.0554
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0048 0.0268
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0013 0.0444
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0025 0.0134
Schistosoma mansoni hypothetical protein 0.0248 0.0554 0.0554
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.0048 0.1041
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0017 0.0411
Schistosoma mansoni unc-13 (munc13) 0.0018 0.0008 0.0008
Brugia malayi MH2 domain containing protein 0.0049 0.0082 0.0209
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0062 0.0112 0.011
Plasmodium falciparum ataxin-2 like protein, putative 0.0184 0.0403 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0151 0.0325 0.0323
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0017 0.0084
Mycobacterium tuberculosis Conserved protein 0.0077 0.0147 0.1249
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0048 0.0268
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0022 0.0017 0.0706
Brugia malayi glutathione reductase 0.0051 0.0086 0.0219
Brugia malayi MH1 domain containing protein 0.0111 0.0228 0.059
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0022 0.0017 0.0088
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0013 0.0028
Brugia malayi F/Y-rich N-terminus family protein 0.0025 0.0023 0.0054
Toxoplasma gondii isocitrate dehydrogenase 0.0151 0.0325 0.803
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0093 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0045 0.0072 0.0184
Mycobacterium ulcerans 3-isopropylmalate dehydrogenase 0.0018 0.0008 0.0118
Wolbachia endosymbiont of Brugia malayi isocitrate dehydrogenase 0.0018 0.0008 0.2649
Mycobacterium tuberculosis Probable lipase LipE 0.0077 0.0147 0.1249
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0127 0.0127
Plasmodium vivax glutathione reductase, putative 0.0051 0.0086 0.2004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Echinococcus multilocularis musashi 0.0221 0.0491 0.0489
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0077 0.0147 0.0147
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0018 0.0101
Loa Loa (eye worm) hypothetical protein 0.0179 0.039 0.1014
Toxoplasma gondii patched family protein 0.0025 0.0025 0.0454
Echinococcus granulosus flap endonuclease 1 0.0028 0.0031 0.0029
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0088
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0133 0.8979
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0017 0.0038
Brugia malayi hypothetical protein 0.0783 0.1829 0.4774
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0151 0.0325 0.803
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0054 0.0301
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0018 0.0016
Loa Loa (eye worm) nuclear factor I 0.0061 0.011 0.0282
Echinococcus granulosus expressed conserved protein 0.0391 0.0896 0.0894
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0013 0.032
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Brugia malayi isocitrate dehydrogenase [NAD] subunit beta, mitochondrial 0.0018 0.0008 0.0016
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0134 0.0132
Giardia lamblia PHD finger protein 15 0.0059 0.0105 1
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0049 0.0082 0.0362
Loa Loa (eye worm) hypothetical protein 0.0535 0.1238 0.3232
Brugia malayi protein C24B5.3 0.0025 0.0025 0.0059
Mycobacterium ulcerans beta-lactamase 0.0077 0.0147 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0129 0.0273 1
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0142 0.0365
Mycobacterium tuberculosis Conserved protein 0.0077 0.0147 0.1249
Plasmodium falciparum phd finger protein, putative 0.0059 0.0105 0.2478
Loa Loa (eye worm) hypothetical protein 0.0077 0.0147 0.0379
Trypanosoma brucei unspecified product 0.0015 0.0001 0.0034
Plasmodium falciparum glutathione reductase 0.0051 0.0086 0.2004
Loa Loa (eye worm) MH1 domain-containing protein 0.0049 0.0082 0.0209
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0077 0.0147 1
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0004 0.0002
Echinococcus multilocularis peregrin 0.0065 0.0119 0.0117
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0018 0.0016
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0018 0.0041
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.0017 0.0015
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0151 0.0325 0.0323
Brugia malayi Isocitrate dehydrogenase 0.0151 0.0325 0.0844
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0032 0.0172
Brugia malayi RNA binding protein 0.0068 0.0127 0.0327
Echinococcus granulosus lysine specific demethylase 5A 0.0073 0.0139 0.0137
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.001 0.008
Schistosoma mansoni acetyl-CoA synthetase 0.0022 0.0017 0.0017
Trypanosoma brucei PAB1-binding protein , putative 0.0184 0.0403 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0077 0.0147 0.0379
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0059 0.0105 0.0105
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0018 0.0445
Brugia malayi Latrophilin receptor protein 2 0.0248 0.0554 0.1443
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0077 0.0147 0.1249
Schistosoma mansoni hypothetical protein 0.0172 0.0375 0.0375
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.006 0.034
Schistosoma mansoni transcription factor LCR-F1 0.0157 0.0338 0.0338
Loa Loa (eye worm) isocitrate dehydrogenase gamma subunit 0.0018 0.0008 0.0016
Schistosoma mansoni isocitrate dehydrogenase 0.0018 0.0008 0.0008
Mycobacterium ulcerans hypothetical protein 0.0077 0.0147 1
Brugia malayi cytoplasmic intermediate filament protein 0.0118 0.0246 0.0638
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0706
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.001 0.0008
Plasmodium vivax JmjC domain containing protein 0.0019 0.001 0.008
Schistosoma mansoni bromodomain containing protein 0.0065 0.012 0.012
Echinococcus multilocularis dna polymerase eta 0.0022 0.0018 0.0016
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.001 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0706
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0142 0.3517
Plasmodium falciparum lipid/sterol:H+ symporter 0.0025 0.0025 0.0454
Loa Loa (eye worm) hypothetical protein 0.0056 0.0097 0.0248
Onchocerca volvulus 0.0074 0.0142 0.0691
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Loa Loa (eye worm) MH2 domain-containing protein 0.0111 0.0228 0.059
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0053
Loa Loa (eye worm) hypothetical protein 0.0109 0.0225 0.0581
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.0017 0.0015
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0109 0.0225 0.0222
Echinococcus granulosus Niemann Pick C1 protein 0.0417 0.0956 0.0954
Leishmania major acetyl-CoA synthetase, putative 0.0022 0.0017 0.0411
Loa Loa (eye worm) hypothetical protein 0.0103 0.0209 0.054
Schistosoma mansoni hypothetical protein 0.0535 0.1238 0.1238
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0048 0.0268
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.009 0.0739
Echinococcus granulosus zinc finger protein 0.0023 0.0019 0.0017
Schistosoma mansoni patched 1 0.0179 0.039 0.039
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0018 0.0102
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0129 0.0273 0.2369
Onchocerca volvulus 0.0025 0.0025 0.0045
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0077 0.0147 0.0379
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0017 0.0411
Schistosoma mansoni hypothetical protein 0.002 0.0012 0.0012
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0248 0.0554 0.1443
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0086 0.0084
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0013 0.0011
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0022 0.0017 0.0706
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0142 0.963
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Leishmania major 4-coumarate:coa ligase-like protein 0.0074 0.0142 0.3517
Onchocerca volvulus 0.0025 0.0025 0.0045
Loa Loa (eye worm) hypothetical protein 0.0248 0.0554 0.1443
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0086 0.2136
Schistosoma mansoni hypothetical protein 0.0019 0.001 0.001
Brugia malayi jmjC domain containing protein 0.0019 0.001 0.002
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0038
Mycobacterium tuberculosis Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) 0.0018 0.0008 0.0015
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0133 0.8979
Brugia malayi hypothetical protein 0.0025 0.0025 0.0059
Echinococcus multilocularis geminin 0.1964 0.4639 0.4638
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0018 0.0445
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0116 0.0242 0.883
Loa Loa (eye worm) hypothetical protein 0.0101 0.0205 0.0531
Brugia malayi photoreceptor-specific nuclear receptor 0.0266 0.0597 0.1556
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0077 0.0075
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0147 0.0846
Loa Loa (eye worm) hypothetical protein 0.0069 0.0128 0.033
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.001 0.001
Brugia malayi Intermediate filament tail domain containing protein 0.0221 0.0491 0.1277
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.0142 0.1408
Schistosoma mansoni jumonji domain containing protein 0.0153 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0706
Brugia malayi acetyltransferase, GNAT family protein 0.0156 0.0335 0.087
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0018 0.0445
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0022 0.0017 0.0411
Brugia malayi MH1 domain containing protein 0.0061 0.011 0.0282
Leishmania major trypanothione reductase 0.0051 0.0086 0.2136
Brugia malayi Bromodomain containing protein 0.0065 0.0119 0.0306
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0077 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0032 0.0172
Loa Loa (eye worm) hypothetical protein 0.0077 0.0147 0.0379
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0017 0.0411
Brugia malayi hypothetical protein 0.0025 0.0025 0.0059
Toxoplasma gondii exonuclease III APE 0.002 0.0013 0.0157
Trypanosoma cruzi hypothetical protein, conserved 0.0077 0.0147 0.3646
Brugia malayi isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial 0.0018 0.0008 0.0016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0185 0.0406 0.0406
Schistosoma mansoni smad 0.0049 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0266 0.0597 0.1556
Onchocerca volvulus 0.0221 0.0491 0.2617
Plasmodium falciparum ataxin-2 like protein, putative 0.0184 0.0403 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0074 0.0142 0.1203
Trypanosoma cruzi target of rapamycin kinase 3 0.0038 0.0054 0.1335
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0054 0.0301
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0017 0.0411
Onchocerca volvulus 0.0077 0.0147 0.072
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0185 0.0406 0.0404
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0127 0.0125
Loa Loa (eye worm) hypothetical protein 0.0077 0.0147 0.0379
Echinococcus multilocularis isocitrate dehydrogenase (NAD) subunit 0.0018 0.0008 0.0006
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0022 0.0017 0.0706
Brugia malayi Patched related family protein 10 0.0025 0.0025 0.0059
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0063 0.0576
Trichomonas vaginalis esterase, putative 0.0077 0.0147 0.0846
Brugia malayi Probable isocitrate dehydrogenase 0.0018 0.0008 0.0016
Trypanosoma cruzi PAB1-binding protein , putative 0.0184 0.0403 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Schistosoma mansoni aldehyde dehydrogenase 0.0071 0.0133 0.0133
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0185 0.0406 0.0406
Mycobacterium tuberculosis Probable oxidoreductase 0.0129 0.0273 0.2369
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0093 0.0185 0.0185
Loa Loa (eye worm) hypothetical protein 0.0195 0.0429 0.1115
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Echinococcus granulosus mothers against decapentaplegic 6 0.0049 0.0082 0.008
Brugia malayi PHD-finger family protein 0.0021 0.0015 0.0033
Loa Loa (eye worm) hypothetical protein 0.0074 0.0142 0.0365
Brugia malayi Patched related family protein 4 0.0025 0.0025 0.0059
Loa Loa (eye worm) hypothetical protein 0.0061 0.011 0.0282
Schistosoma mansoni lamin 0.0221 0.0491 0.0491
Echinococcus granulosus mothers against decapentaplegic 2 0.0049 0.0082 0.008
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Trichomonas vaginalis antibiotic synthetase, putative 0.0022 0.0017 0.0084
Toxoplasma gondii propionate-CoA ligase 0.0022 0.0017 0.025
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0151 0.0325 0.8063
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0783 0.1828 0.4773
Plasmodium vivax ataxin-2 like protein, putative 0.0184 0.0403 1
Brugia malayi Myosin head containing protein 0.0025 0.0025 0.0059
Echinococcus granulosus jumonji domain containing protein 0.0082 0.016 0.0158
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0063 0.5727
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0185 0.0406 0.0404
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0031 0.0077
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.0142 0.5045
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0002 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Echinococcus granulosus dna polymerase eta 0.0022 0.0018 0.0016
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0074 0.0142 0.5045
Schistosoma mansoni hypothetical protein 0.1964 0.4639 0.4639
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.004 0.022
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0083 0.0161 0.0159
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0018 0.0018
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0116 0.0242 0.2094
Brugia malayi AMP-binding enzyme family protein 0.0074 0.0142 0.0365
Echinococcus multilocularis GPCR, family 2 0.0248 0.0554 0.0552
Toxoplasma gondii isocitrate dehydrogenase 0.0151 0.0325 0.803
Brugia malayi PHD-finger family protein 0.0059 0.0105 0.0269
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0022 0.0017 0.0014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0185 0.0406 0.0406
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0022 0.0017 0.0411
Brugia malayi hypothetical protein 0.0119 0.0248 0.0642
Echinococcus multilocularis jumonji domain containing protein 0.0082 0.016 0.0158
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0017 0.0706
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0077 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0025 0.0134
Loa Loa (eye worm) hypothetical protein 0.0219 0.0486 0.1265
Loa Loa (eye worm) Smad1 0.0111 0.0228 0.059
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0019 0.0019
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0013 0.032
Plasmodium falciparum acyl-CoA synthetase 0.0056 0.0097 0.2278
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0013 0.0063
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0022 0.0017 0.0038
Brugia malayi latrophilin 2 splice variant baaae 0.0535 0.1238 0.3232
Loa Loa (eye worm) beta-lactamase 0.0077 0.0147 0.0379
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0022 0.0017 0.0088
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0083 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0147 0.0846
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0001 0.0034
Brugia malayi hypothetical protein 0.0157 0.0338 0.0878
Loa Loa (eye worm) latrophilin receptor protein 2 0.0248 0.0554 0.1443
Mycobacterium ulcerans acetyl-CoA synthetase 0.0022 0.0017 0.0706
Trichomonas vaginalis conserved hypothetical protein 0.0179 0.039 0.2267
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0031 0.0168
Echinococcus multilocularis isocitrate dehydrogenase 0.0151 0.0325 0.0323
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0022 0.0017 0.0038
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0077 0.1902
Echinococcus multilocularis lamin dm0 0.0221 0.0491 0.0489
Plasmodium falciparum thioredoxin reductase 0.0051 0.0086 0.2004
Echinococcus multilocularis beta LACTamase domain containing family member 0.0077 0.0147 0.0145
Entamoeba histolytica acyl-coA synthetase, putative 0.0074 0.0142 0.1408
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Plasmodium vivax patched family protein, putative 0.0025 0.0025 0.0454
Trichomonas vaginalis D-aminoacylase, putative 0.0077 0.0147 0.0846
Loa Loa (eye worm) pax transcription factor protein 2 0.0505 0.1166 0.3043
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0077 0.1783
Schistosoma mansoni smad 0.0111 0.0228 0.0228
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0025 0.0134
Schistosoma mansoni hypothetical protein 0.0172 0.0375 0.0375
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0018 0.0041
Brugia malayi Niemann-Pick C1 protein precursor 0.0417 0.0956 0.2494
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Echinococcus granulosus mothers against decapentaplegic 5 0.0111 0.0228 0.0226
Brugia malayi jmjC domain containing protein 0.0019 0.001 0.002
Brugia malayi jmjC domain containing protein 0.0073 0.0139 0.0357
Loa Loa (eye worm) RNA binding protein 0.0068 0.0127 0.0327
Loa Loa (eye worm) hypothetical protein 0.0018 0.0008 0.0016
Loa Loa (eye worm) MH1 domain-containing protein 0.0111 0.0228 0.059
Mycobacterium ulcerans aldehyde dehydrogenase 0.0071 0.0133 0.8979
Mycobacterium tuberculosis Probable hydrolase 0.0077 0.0147 0.1249
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.001 0.0008
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0151 0.0325 0.8063
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0077 0.0435
Onchocerca volvulus 0.0077 0.0147 0.072
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Loa Loa (eye worm) PHD-finger family protein 0.0059 0.0105 0.0269
Plasmodium vivax SET domain protein, putative 0.0093 0.0185 0.4499
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3458 0.8198 0.8198
Entamoeba histolytica hypothetical protein 0.0157 0.0338 0.3479
Echinococcus granulosus peregrin 0.0065 0.0119 0.0117
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0165
Echinococcus granulosus beta LACTamase domain containing family member 0.0077 0.0147 0.0145
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0022 0.0017 0.0088
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0423 0.0972 0.0972
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0037 0.0206
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Entamoeba histolytica hypothetical protein 0.0157 0.0338 0.3479
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0022 0.0017 0.025
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0007 0.0007
Echinococcus granulosus sterol regulatory element binding protein 0.0179 0.039 0.0388
Schistosoma mansoni DNA polymerase eta 0.0022 0.0018 0.0018
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0071 0.0133 0.1121
Brugia malayi beta-lactamase family protein 0.0077 0.0147 0.0379
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0022 0.0017 0.025
Loa Loa (eye worm) hypothetical protein 0.0059 0.0105 0.0269
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0018 0.0092
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0165
Brugia malayi hypothetical protein 0.0184 0.0403 0.1048
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0007 0.0005
Schistosoma mansoni protein phosphatase 2C 0.0019 0.001 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0048 0.0268
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.0017 0.0017
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0031 0.0781
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0116 0.0242 0.2094
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.002
Loa Loa (eye worm) patched family protein 0.0025 0.0025 0.0059
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0116 0.0242 0.2094
Brugia malayi protein C24B5.3 0.0025 0.0025 0.0059
Echinococcus granulosus Niemann Pick C1 protein 0.0595 0.1382 0.138
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0031 0.0626
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0013 0.0063
Onchocerca volvulus 0.0783 0.1829 1
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.001 0.0008
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0116 0.0242 0.2094
Loa Loa (eye worm) hypothetical protein 0.0217 0.0481 0.1252
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0109 0.0225 0.0225
Brugia malayi Calcitonin receptor-like protein seb-1 0.0783 0.1828 0.4773
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.001 0.008
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0248 0.0554 0.0552
Schistosoma mansoni hypothetical protein 0.1964 0.4639 0.4639
Echinococcus granulosus lamin 0.0221 0.0491 0.0489
Leishmania major isocitrate dehydrogenase, putative 0.0018 0.0008 0.0206
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0004 0.0004
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0107 0.0218 0.0216
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0077 0.1902
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0139 0.0139
Brugia malayi MH1 domain containing protein 0.0111 0.0228 0.059
Onchocerca volvulus Protein patched homolog 0.0025 0.0025 0.0045
Loa Loa (eye worm) hypothetical protein 0.0184 0.0403 0.1048
Leishmania major DNA polymerase eta, putative 0.0022 0.0018 0.0445
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0077 0.0077
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0105 0.2478
Echinococcus multilocularis smad 0.0111 0.0228 0.0226
Echinococcus multilocularis tumor protein p63 0.2105 0.4977 0.4976
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Trichomonas vaginalis mercuric reductase, putative 0.0018 0.0007 0.0026
Echinococcus granulosus TGF beta signal transducer SmadC 0.0111 0.0228 0.0226
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Mycobacterium leprae Probable lipase LipE 0.0077 0.0147 0.5242
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0038 0.0054 0.1335
Schistosoma mansoni zinc finger protein 0.0023 0.0019 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0706
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0193 0.0424 0.0422
Schistosoma mansoni intermediate filament proteins 0.0221 0.0491 0.0491
Mycobacterium ulcerans acyl-CoA synthetase 0.0074 0.0142 0.963
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0193 0.0424 0.0422
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0013 0.0157
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0156 0.0335 0.0335
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0018 0.0092
Brugia malayi PHD-finger family protein 0.0028 0.0031 0.0076
Onchocerca volvulus 0.0093 0.0185 0.093
Schistosoma mansoni jumonji/arid domain-containing protein 0.0073 0.0139 0.0139
Brugia malayi jmjC domain containing protein 0.0019 0.001 0.002
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0312
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0031 0.2528
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.001 0.0094
Echinococcus granulosus histone lysine methyltransferase setb 0.0109 0.0225 0.0222
Loa Loa (eye worm) hypothetical protein 0.0074 0.0142 0.0365
Loa Loa (eye worm) intermediate filament protein 0.0221 0.0491 0.1277
Trypanosoma brucei trypanothione reductase 0.0051 0.0086 0.2136
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0088
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0007 0.0005
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0002 0.0002
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0077 0.0721
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0007 0.0165
Loa Loa (eye worm) hypothetical protein 0.0043 0.0068 0.0172
Echinococcus multilocularis zinc finger protein 0.0023 0.0019 0.0017
Brugia malayi MH2 domain containing protein 0.1623 0.3828 1
Brugia malayi N-terminal motif family protein 0.0195 0.0429 0.1115
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0139 0.0357
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0032 0.0172
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0156 0.0335 0.0333
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0002 0.0053
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0111 0.0228 0.0226
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0022 0.0017 0.0706
Echinococcus granulosus GPCR family 2 0.0248 0.0554 0.0552
Mycobacterium leprae conserved hypothetical protein 0.0077 0.0147 0.5242
Echinococcus granulosus Protein patched homolog 1 0.0179 0.039 0.0388
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0022 0.0017 0.0088
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0157 0.0338 0.0336
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0022 0.0017 0.0706
Brugia malayi beta-lactamase family protein 0.0077 0.0147 0.0379
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0706
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.001 0.0008
Schistosoma mansoni hypothetical protein 0.0172 0.0375 0.0375
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0185 0.0406 0.0404
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0165
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0013 0.0055
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0074 0.0142 0.963
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0048 0.0046
Schistosoma mansoni hypothetical protein 0.0248 0.0554 0.0554
Brugia malayi intermediate filament protein 0.0221 0.0491 0.1277
Brugia malayi mothers against decapentaplegic homolog 3 0.0049 0.0082 0.0209
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0022 0.0017 0.0088
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0022 0.0017 0.0038
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0783 0.1828 0.4773
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0086 0.2004
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0056 0.0097 0.6436
Loa Loa (eye worm) hypothetical protein 0.0022 0.0017 0.0038
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0195 0.0429 0.2275
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0077 0.1902
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0017 0.0706
Onchocerca volvulus 0.0025 0.0025 0.0045
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0086 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0025 0.0134
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0048 0.0046
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0048 0.0268
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.001 0.002
Echinococcus granulosus tumor protein p63 0.2105 0.4977 0.4976
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0089 0.0177 0.0175
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0185 0.0406 0.1055
Toxoplasma gondii hypothetical protein 0.0025 0.0025 0.0454
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0025 0.0134
Echinococcus multilocularis Niemann Pick C1 protein 0.0595 0.1382 0.138
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0011 0.0276
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0013 0.0157
Entamoeba histolytica hypothetical protein 0.0157 0.0338 0.3479
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0001 0.0034
Brugia malayi Pre-SET motif family protein 0.0093 0.0185 0.0478
Echinococcus granulosus lamin dm0 0.0221 0.0491 0.0489
Brugia malayi Bromodomain containing protein 0.0041 0.0062 0.0157
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0071 0.0133 0.0131
Brugia malayi Isocitrate dehydrogenase subunit gamma, mitochondrial precursor 0.0018 0.0008 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0007 0.0165
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0088
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0077 0.1902
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.009 0.0739
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.001 0.002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0025 0.0134
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0019 0.001 0.0094
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0077 0.0195
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0013 0.0634
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0077 0.1902
Trypanosoma brucei unspecified product 0.0015 0.0001 0.0034
Onchocerca volvulus 0.0077 0.0147 0.072
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0127 0.0327
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0022 0.0017 0.0411
Brugia malayi Patched related family protein 12 0.0025 0.0025 0.0059
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0157 0.0338 0.0336
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0007 0.0165
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0151 0.0325 0.0323
Loa Loa (eye worm) hypothetical protein 0.0103 0.0209 0.054
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0007 0.0165
Echinococcus multilocularis mothers against decapentaplegic 6 0.0049 0.0082 0.008
Brugia malayi beta-lactamase 0.0077 0.0147 0.0379
Toxoplasma gondii patched family protein 0.0025 0.0025 0.0454
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0221 0.0491 0.1277
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0018 0.0101
Schistosoma mansoni hypothetical protein 0.0083 0.0161 0.0161
Giardia lamblia DINP protein human, muc B family 0.0022 0.0018 0.115
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Schistosoma mansoni lamin 0.0221 0.0491 0.0491
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0185 0.0406 0.0404
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0105 0.2478
Brugia malayi Patched family protein 0.0025 0.0025 0.0059
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.009 0.0739
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Echinococcus multilocularis phd:f box containing protein 0.0019 0.001 0.0008
Schistosoma mansoni aldehyde dehydrogenase 0.0071 0.0133 0.0133
Entamoeba histolytica hypothetical protein 0.0157 0.0338 0.3479
Echinococcus granulosus phd:f box containing protein 0.0019 0.001 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0007 0.0165
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0077 0.0435
Echinococcus granulosus PHD finger protein rhinoceros 0.0059 0.0105 0.0103
Brugia malayi TAR-binding protein 0.0068 0.0127 0.0327
Echinococcus multilocularis expressed conserved protein 0.0391 0.0896 0.0894
Loa Loa (eye worm) glutathione reductase 0.0051 0.0086 0.0219
Loa Loa (eye worm) patched family protein 0.0025 0.0025 0.0059
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0056 0.0097 0.0804
Onchocerca volvulus 0.0308 0.0698 0.3762
Schistosoma mansoni smad1 5 8 and 0.0111 0.0228 0.0228
Mycobacterium tuberculosis Probable lipase LipD 0.0077 0.0147 0.1249
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0018 0.0445
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0127 0.0327
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0022 0.0017 0.0706
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0007 0.0165
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0019 0.0009 0.0024
Trichomonas vaginalis penicillin-binding protein, putative 0.0077 0.0147 0.0846
Entamoeba histolytica acyl-CoA synthetase, putative 0.0074 0.0142 0.1408
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0018 0.0445
Schistosoma mansoni flap endonuclease-1 0.0025 0.0025 0.0025
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0017 0.0088
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0086 0.0219
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0013 0.032
Mycobacterium ulcerans lipase LipD 0.0077 0.0147 1
Brugia malayi MH1 domain containing protein 0.0061 0.011 0.0282
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0127 0.0127
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0007 0.0165
Loa Loa (eye worm) hypothetical protein 0.0056 0.0097 0.0248
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0013 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.001 0.002
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0185 0.0406 0.1055
Loa Loa (eye worm) hypothetical protein 0.0077 0.0147 0.0379
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0018 0.0018
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0077 0.1902
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0022 0.0017 0.0312
Schistosoma mansoni cellular tumor antigen P53 0.0308 0.0698 0.0698
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0077 0.0439
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0022 0.0017 0.0088
Loa Loa (eye worm) hypothetical protein 0.0783 0.1829 0.4774
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.001 0.0244
Echinococcus granulosus Smad4 0.0111 0.0228 0.0226
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0018 0.0436
Brugia malayi CHE-14 protein 0.0179 0.039 0.1014
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0037 0.0053 0.0134
Loa Loa (eye worm) hypothetical protein 0.0025 0.0025 0.0059
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0017 0.0038
Loa Loa (eye worm) hypothetical protein 0.0221 0.0491 0.1277
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0118 0.0246 0.0638
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0022 0.0017 0.0014
Mycobacterium tuberculosis Probable esterase LipL 0.0077 0.0147 0.1249
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0093 0.0185 0.0183
Onchocerca volvulus 0.0025 0.0025 0.0045
Trichomonas vaginalis set domain proteins, putative 0.0735 0.1714 1
Loa Loa (eye worm) hypothetical protein 0.0783 0.1828 0.4773
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0031 0.0171
Loa Loa (eye worm) hypothetical protein 0.0056 0.0097 0.0248
Plasmodium vivax hypothetical protein, conserved 0.0019 0.001 0.0094
Trypanosoma brucei unspecified product 0.0022 0.0018 0.0445
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0151 0.0325 0.8063
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0031 0.0244

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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