Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.1256 | 0.2505 |
Onchocerca volvulus | 0.0038 | 0.1256 | 0.5 | |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.1256 | 0.2505 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.1256 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.1256 | 0.5 |
Onchocerca volvulus | 0.0038 | 0.1256 | 0.5 | |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.1256 | 0.5 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.1256 | 0.2505 |
Brugia malayi | MH2 domain containing protein | 0.0128 | 0.5014 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.1256 | 0.5 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.1256 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0038 | 0.1256 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.1256 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1256 | 0.2505 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0128 | 0.5014 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1256 | 0.2505 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.1256 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1256 | 0.2505 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1256 | 0.2505 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1256 | 0.2505 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1256 | 0.2505 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.1256 | 0.5 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.1256 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.1256 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.1256 | 0.2505 |
Onchocerca volvulus | 0.0038 | 0.1256 | 0.5 | |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.1256 | 0.5 |
Mycobacterium ulcerans | beta-lactamase | 0.0038 | 0.1256 | 0.5 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.1256 | 0.2505 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.1256 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.1256 | 0.5 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0038 | 0.1256 | 0.5 |
Mycobacterium ulcerans | lipase LipD | 0.0038 | 0.1256 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.1256 | 0.5 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.1256 | 0.5 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.1256 | 1 |
Brugia malayi | beta-lactamase | 0.0038 | 0.1256 | 0.2505 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.1256 | 0.5 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.1256 | 0.5 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.1256 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0128 | 0.5014 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.