Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0453 | 0.271 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0008 | 0.0041 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0008 | 0.0061 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0318 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0008 | 0.0045 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0097 | 0.2145 |
Brugia malayi | RNA, U transporter 1 | 0.0081 | 0.0366 | 0.2956 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0008 | 0.0045 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0037 | 0.0111 | 0.0121 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0475 | 0.2846 |
Brugia malayi | beta-lactamase family protein | 0.0073 | 0.0318 | 0.2566 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0015 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0037 | 0.0108 | 0.3388 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0008 | 0.0008 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0184 | 0.0994 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0184 | 0.0994 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0008 | 0.0061 |
Plasmodium falciparum | thioredoxin reductase | 0.0037 | 0.0108 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0077 | 0.0415 |
Treponema pallidum | recombinase A | 0.0105 | 0.0506 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0073 | 0.0318 | 0.6273 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0073 | 0.0318 | 0.6273 |
Brugia malayi | Muscleblind-like protein | 0.0145 | 0.074 | 0.5979 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0077 | 0.0415 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0073 | 0.0318 | 0.1718 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0077 | 0.0084 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0008 | 0.0041 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0008 | 0.0061 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0059 | 0.1854 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0097 | 0.2145 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0084 | 0.0383 | 0.0383 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0167 | 0.1348 |
Toxoplasma gondii | thioredoxin reductase | 0.0037 | 0.0108 | 0.3388 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0318 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0037 | 0.0108 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0008 | 0.0061 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0464 | 0.261 | 0.261 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.1849 | 1 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0015 | 0.047 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0073 | 0.0318 | 0.0318 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0008 | 0.0045 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0008 | 0.0041 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0167 | 0.0902 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0263 | 0.1425 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.0036 | 0.1127 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0008 | 0.0041 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0073 | 0.0318 | 0.1718 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0008 | 0.0045 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0015 | 0.0089 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0008 | 0.0061 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0318 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0097 | 0.2145 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0077 | 0.0415 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0008 | 0.0041 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0184 | 0.0994 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0008 | 0.0041 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0184 | 0.0201 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.0036 | 0.1127 |
Echinococcus multilocularis | muscleblind protein | 0.0145 | 0.074 | 0.0809 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0008 | 0.0045 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0124 | 0.0671 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0008 | 0.0041 |
Leishmania major | trypanothione reductase | 0.0037 | 0.0108 | 0.3388 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0073 | 0.0318 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.0263 | 0.1577 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0059 | 0.0353 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0027 | 0.0863 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0097 | 0.0525 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0036 | 0.3326 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0015 | 0.047 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.0036 | 0.3326 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0077 | 0.046 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0008 | 0.0061 |
Toxoplasma gondii | ABC1 family protein | 0.0073 | 0.0318 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0073 | 0.0318 | 1 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.0263 | 0.2128 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0077 | 0.046 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0008 | 0.0041 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0027 | 0.0863 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0291 | 0.1742 |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.0419 | 0.2264 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0015 | 0.1387 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0008 | 0.0045 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0008 | 0.0041 |
Wolbachia endosymbiont of Brugia malayi | recombinase A | 0.0105 | 0.0506 | 1 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0133 | 0.0718 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0059 | 0.1854 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.023 | 0.1238 | 0.1353 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0027 | 0.0863 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0008 | 0.0041 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0008 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0187 | 0.1119 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0133 | 0.0718 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0059 | 0.5473 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0073 | 0.0318 | 0.0347 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0133 | 0.0718 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0318 | 0.1902 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0073 | 0.0318 | 0.2566 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0084 | 0.0383 | 0.0383 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0008 | 0.0008 |
Mycobacterium leprae | RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. | 0.0105 | 0.0506 | 0.0594 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0318 | 0.0318 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0036 | 0.1127 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0015 | 0.047 |
Brugia malayi | glutathione reductase | 0.0037 | 0.0108 | 0.0869 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0137 | 0.0693 | 0.0758 |
Trypanosoma cruzi | DNA repair protein, putative | 0.0032 | 0.0081 | 0.2562 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0084 | 0.0383 | 0.0383 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0008 | 0.0045 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0015 | 0.033 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0097 | 0.0461 | 0.2494 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0008 | 0.0061 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0037 | 0.0108 | 0.0108 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0015 | 0.047 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0184 | 0.0994 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0097 | 0.0784 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0008 | 0.0041 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0059 | 0.0318 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0027 | 0.0863 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0077 | 0.0415 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0059 | 0.1854 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0008 | 0.0061 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.0036 | 0.1127 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0073 | 0.0318 | 0.0318 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0073 | 0.0318 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.0475 | 0.2846 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0263 | 0.1425 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0073 | 0.0318 | 1 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0015 | 0.047 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0073 | 0.0318 | 0.1902 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0059 | 0.0318 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0167 | 0.0182 |
Mycobacterium tuberculosis | Probable replicative DNA helicase DnaB | 0.1621 | 0.9386 | 0.9386 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0133 | 0.0145 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0084 | 0.0383 | 0.0207 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0008 | 0.0008 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.0453 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0037 | 0.0108 | 0.0644 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0073 | 0.0318 | 0.1718 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0318 | 0.1902 |
Trypanosoma brucei | recA bacterial DNA recombination protein, putative | 0.0032 | 0.0081 | 0.2562 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0077 | 0.0415 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0008 | 0.0061 |
Brugia malayi | RNA binding protein | 0.0063 | 0.0263 | 0.2128 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0073 | 0.0318 | 0.0318 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0015 | 0.047 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.0263 | 0.0288 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0015 | 0.0121 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0124 | 0.0671 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0008 | 0.0008 |
Echinococcus granulosus | geminin | 0.0334 | 0.1849 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0184 | 0.0994 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0084 | 0.0383 | 0.0383 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0093 | 0.0438 | 0.0438 |
Schistosoma mansoni | hypothetical protein | 0.0304 | 0.167 | 0.9032 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0615 | 0.3495 | 1 |
Mycobacterium ulcerans | recombinase A | 0.0105 | 0.0506 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0073 | 0.0318 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0008 | 0.0008 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0318 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0184 | 0.1101 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0318 | 0.1902 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.023 | 0.1238 | 0.6695 |
Echinococcus multilocularis | snurportin 1 | 0.0304 | 0.167 | 0.1826 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0008 | 0.0061 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0008 | 0.0041 |
Brugia malayi | hypothetical protein | 0.023 | 0.1238 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0073 | 0.0318 | 0.6273 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.0036 | 0.1127 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0008 | 0.0041 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0008 | 0.0008 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0093 | 0.0438 | 0.0379 |
Chlamydia trachomatis | recombinase RecA | 0.0105 | 0.0506 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0263 | 0.1425 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0008 | 0.0061 |
Mycobacterium tuberculosis | Probable reductase | 0.0084 | 0.0383 | 0.0383 |
Brugia malayi | beta-lactamase family protein | 0.0073 | 0.0318 | 0.2566 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0318 | 0.1902 |
Schistosoma mansoni | ran | 0.0021 | 0.0015 | 0.0081 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0008 | 0.0041 |
Loa Loa (eye worm) | beta-lactamase | 0.0073 | 0.0318 | 0.1902 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0093 | 0.0438 | 0.0438 |
Trypanosoma brucei | trypanothione reductase | 0.0037 | 0.0108 | 0.3388 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0097 | 0.0525 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0008 | 0.0061 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0027 | 0.0605 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0015 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.1238 | 0.7412 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0008 | 0.0061 |
Schistosoma mansoni | hypothetical protein | 0.0334 | 0.1849 | 1 |
Echinococcus granulosus | snurportin 1 | 0.0304 | 0.167 | 0.9032 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0059 | 0.1854 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0036 | 0.0214 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.0263 | 0.1577 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0008 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0318 | 0.1902 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0133 | 0.1073 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0077 | 0.0621 |
Echinococcus granulosus | muscleblind protein | 0.0145 | 0.074 | 0.4003 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.0291 | 0.235 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0073 | 0.0318 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0008 | 0.0045 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0304 | 0.167 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0077 | 0.0415 |
Plasmodium vivax | glutathione reductase, putative | 0.0037 | 0.0108 | 0.3388 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0008 | 0.0045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0008 | 0.0045 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0318 | 0.0318 |
Onchocerca volvulus | 0.0073 | 0.0318 | 1 | |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0008 | 0.0061 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0008 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.074 | 0.4432 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.0453 | 0.2448 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0008 | 0.0008 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.0036 | 0.1127 |
Brugia malayi | beta-lactamase | 0.0073 | 0.0318 | 0.2566 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.0263 | 0.1425 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0008 | 0.0041 |
Brugia malayi | Thioredoxin reductase | 0.0037 | 0.0108 | 0.0869 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0015 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0318 | 0.1902 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.0475 | 0.384 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0097 | 0.0525 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0133 | 0.0795 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0137 | 0.0693 | 0.3748 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0077 | 0.0084 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0077 | 0.0084 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0059 | 0.0064 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.1581 | 0.9149 | 1 |
Schistosoma mansoni | ran | 0.0021 | 0.0015 | 0.0081 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.0419 | 0.0458 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0167 | 0.0902 |
Onchocerca volvulus | 0.0073 | 0.0318 | 1 | |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0073 | 0.0318 | 0.0318 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0008 | 0.0045 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.0263 | 0.2128 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0291 | 0.1573 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0093 | 0.0438 | 0.0438 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0008 | 0.0045 |
Mycobacterium ulcerans | hypothetical protein | 0.0073 | 0.0318 | 0.6273 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0077 | 0.0621 |
Plasmodium vivax | hypothetical protein, conserved | 0.0073 | 0.0318 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0008 | 0.0041 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0037 | 0.0108 | 0.3388 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0133 | 0.0145 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.0453 | 0.3656 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0184 | 0.1485 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0097 | 0.2145 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0184 | 0.0201 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0008 | 0.0041 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0124 | 0.0671 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.01 | 0.0475 | 0.384 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0059 | 0.0476 |
Onchocerca volvulus | 0.0047 | 0.0167 | 0.5136 | |
Echinococcus multilocularis | geminin | 0.0334 | 0.1849 | 0.2022 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0077 | 0.0415 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0008 | 0.0041 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0073 | 0.0318 | 0.6273 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0008 | 0.0041 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0027 | 0.0863 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0008 | 0.0045 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.0453 | 0.0495 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0036 | 0.0289 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0037 | 0.0111 | 0.0598 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0073 | 0.0318 | 0.0318 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0084 | 0.0383 | 0.0383 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0008 | 0.0061 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0015 | 0.047 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0008 | 0.0061 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0124 | 0.0671 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0133 | 0.418 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0008 | 0.0061 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0263 | 0.1425 |
Trypanosoma cruzi | DNA repair protein, putative | 0.0032 | 0.0081 | 0.2562 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0133 | 0.0795 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0008 | 0.0061 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0073 | 0.0318 | 0.0318 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0008 | 0.0041 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0008 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.074 | 0.4432 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0008 | 0.0045 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0097 | 0.0106 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0008 | 0.0041 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0145 | 0.074 | 0.0809 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0318 | 0.0318 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0263 | 0.1425 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0008 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0008 | 0.0045 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0073 | 0.0318 | 0.0318 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.0263 | 0.1577 |
Onchocerca volvulus | 0.0073 | 0.0318 | 1 | |
Loa Loa (eye worm) | glutathione reductase | 0.0037 | 0.0108 | 0.0644 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.