Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0181 | 0.1905 | 0.4416 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0308 | 0.3348 | 1 |
Brugia malayi | hypothetical protein | 0.0024 | 0.013 | 0.0302 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0106 | 0.1057 | 0.3102 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0308 | 0.3348 | 0.5 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0059 | 0.0137 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0074 | 0.0688 | 0.1595 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0221 | 0.0221 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.1016 | 0.2355 |
Schistosoma mansoni | dep domain containing protein | 0.0018 | 0.0059 | 0.0059 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.047 | 0.5192 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0221 | 0.0221 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0202 | 0.2144 | 0.4099 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.3159 | 1 |
Schistosoma mansoni | Smad4 | 0.0027 | 0.0157 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0688 | 0.1595 |
Schistosoma mansoni | smad | 0.0027 | 0.0157 | 0.0157 |
Echinococcus granulosus | Smad4 | 0.0027 | 0.0157 | 0.0157 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0018 | 0.0059 | 0.0059 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.0688 | 0.1281 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0688 | 0.2179 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0074 | 0.0688 | 0.1281 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.0688 | 0.1281 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.0688 | 0.2179 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0074 | 0.0688 | 0.1281 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0688 | 0.1595 |
Brugia malayi | Isocitrate dehydrogenase | 0.0015 | 0.0027 | 0.0062 |
Schistosoma mansoni | regulator of G protein signaling | 0.0018 | 0.0059 | 0.0059 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0291 | 0.3159 | 0.7801 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0027 | 0.0027 |
Onchocerca volvulus | 0.0018 | 0.0059 | 0.0146 | |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0018 | 0.0059 | 0.0059 |
Brugia malayi | Smad1 | 0.0027 | 0.0157 | 0.0363 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0018 | 0.0059 | 0.0059 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0221 | 0.0512 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0308 | 0.3348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.013 | 0.0302 |
Leishmania major | hypothetical protein, conserved | 0.0074 | 0.0688 | 0.2113 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0018 | 0.0059 | 0.0137 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0196 | 0.2077 | 0.2077 |
Echinococcus multilocularis | smad | 0.0027 | 0.0157 | 0.0157 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0018 | 0.0059 | 0.0059 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0074 | 0.0688 | 0.2179 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0291 | 0.3159 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0074 | 0.0688 | 0.1281 |
Echinococcus multilocularis | Smad4 | 0.0027 | 0.0157 | 0.0157 |
Toxoplasma gondii | ABC1 family protein | 0.0074 | 0.0688 | 0.1992 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0027 | 0.0027 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0074 | 0.0688 | 0.2179 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0074 | 0.0688 | 0.2113 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0202 | 0.2144 | 0.2144 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0196 | 0.2077 | 0.2077 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0027 | 0.0157 | 0.0157 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0181 | 0.1905 | 0.1905 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0196 | 0.2077 | 0.4814 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0291 | 0.3159 | 0.3159 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.3159 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0074 | 0.0688 | 0.1281 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0027 | 0.0084 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.0648 | 0.1502 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0059 | 0.0137 |
Brugia malayi | Probable ClpP-like protease | 0.0308 | 0.3348 | 0.7759 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0027 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.0648 | 0.0648 |
Brugia malayi | MH2 domain containing protein | 0.0027 | 0.0157 | 0.0363 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0027 | 0.0157 | 0.0363 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0074 | 0.0688 | 0.2179 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0221 | 0.0221 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0018 | 0.0059 | 0.0137 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0181 | 0.1905 | 0.1905 |
Loa Loa (eye worm) | Smad1 | 0.0027 | 0.0157 | 0.0363 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0018 | 0.0059 | 0.0059 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0196 | 0.2077 | 0.2077 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0027 | 0.0157 | 0.0157 |
Giardia lamblia | Kinase, PLK | 0.0291 | 0.3159 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0018 | 0.0059 | 0.0098 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0291 | 0.3159 | 0.3159 |
Brugia malayi | MH2 domain containing protein | 0.0027 | 0.0157 | 0.0363 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.013 | 0.0412 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0221 | 0.0221 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0027 | 0.0157 | 0.0157 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0308 | 0.3348 | 1 |
Schistosoma mansoni | kinase | 0.0148 | 0.1533 | 0.1533 |
Onchocerca volvulus | 0.0074 | 0.0688 | 0.17 | |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0018 | 0.0059 | 0.0146 |
Loa Loa (eye worm) | nuclear factor I | 0.0015 | 0.0021 | 0.0048 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0074 | 0.0688 | 0.0688 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0018 | 0.0059 | 0.0137 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0059 | 0.0137 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0018 | 0.0059 | 0.0059 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.0688 | 0.2179 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0059 | 0.0137 |
Brugia malayi | MH2 domain containing protein | 0.0393 | 0.4315 | 1 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0202 | 0.2144 | 0.2144 |
Brugia malayi | MH1 domain containing protein | 0.0015 | 0.0021 | 0.0048 |
Entamoeba histolytica | hypothetical protein | 0.0181 | 0.1905 | 0.6032 |
Plasmodium vivax | hypothetical protein, conserved | 0.0074 | 0.0688 | 0.1992 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0221 | 0.0512 |
Mycobacterium tuberculosis | Conserved protein | 0.0074 | 0.0688 | 0.1281 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0018 | 0.0059 | 0.0137 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0291 | 0.3159 | 0.732 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0221 | 0.0221 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.1016 | 0.2355 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0074 | 0.0688 | 0.2179 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0202 | 0.2144 | 0.4099 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0074 | 0.0688 | 0.1281 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0202 | 0.2144 | 0.5472 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0308 | 0.3348 | 0.3348 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0027 | 0.0157 | 0.0363 |
Brugia malayi | MH1 domain containing protein | 0.0027 | 0.0157 | 0.0363 |
Entamoeba histolytica | hypothetical protein | 0.0181 | 0.1905 | 0.6032 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0074 | 0.0688 | 0.1595 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0221 | 0.0512 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0291 | 0.3159 | 1 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0308 | 0.3348 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0221 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0021 | 0.0048 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.013 | 0.0312 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0144 | 0.1489 | 0.4715 |
Brugia malayi | isocitrate dehydrogenase | 0.0015 | 0.0027 | 0.0062 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.3159 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.013 | 0.0312 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0027 | 0.0157 | 0.0157 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0027 | 0.0027 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.3159 | 1 |
Schistosoma mansoni | dishevelled | 0.0018 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0015 | 0.0027 | 0.0062 |
Brugia malayi | beta-lactamase | 0.0074 | 0.0688 | 0.1595 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0074 | 0.0688 | 0.0688 |
Echinococcus granulosus | smad | 0.0027 | 0.0157 | 0.0157 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0015 | 0.0027 | 0.0027 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0074 | 0.0688 | 0.1281 |
Onchocerca volvulus | 0.0074 | 0.0688 | 0.17 | |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.1016 | 0.2355 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0221 | 0.0221 |
Brugia malayi | DIX domain containing protein | 0.0018 | 0.0059 | 0.0137 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0221 | 0.0221 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0074 | 0.0688 | 0.0688 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0308 | 0.3348 | 0.5 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0032 | 0.0074 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0393 | 0.4315 | 1 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.037 | 0.4049 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.4049 | 0.9384 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0308 | 0.3348 | 0.5 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0018 | 0.0059 | 0.0059 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0015 | 0.0027 | 0.0084 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0074 | 0.0688 | 0.1281 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.013 | 0.0331 |
Brugia malayi | beta-lactamase family protein | 0.0074 | 0.0688 | 0.1595 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0059 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0688 | 0.1595 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0688 | 0.1595 |
Mycobacterium leprae | ATP-dependent Clp protease proteolytic subunit 1 | 0.0106 | 0.1057 | 0.1386 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0015 | 0.0027 | 0.0027 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0308 | 0.3348 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0181 | 0.1905 | 0.6032 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0018 | 0.0059 | 0.0059 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0157 | 0.0157 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.3159 | 1 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0018 | 0.0059 | 0.0137 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0074 | 0.0688 | 0.0688 |
Loa Loa (eye worm) | beta-lactamase | 0.0074 | 0.0688 | 0.1595 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.1905 | 0.1905 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.3348 | 0.7759 |
Toxoplasma gondii | hypothetical protein | 0.0106 | 0.1057 | 0.3102 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0196 | 0.2077 | 0.2077 |
Brugia malayi | beta-lactamase family protein | 0.0074 | 0.0688 | 0.1595 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0018 | 0.0059 | 0.0059 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0106 | 0.1057 | 0.3102 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0018 | 0.0059 | 0.0059 |
Entamoeba histolytica | hypothetical protein | 0.0181 | 0.1905 | 0.6032 |
Brugia malayi | MH1 domain containing protein | 0.0027 | 0.0157 | 0.0363 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0018 | 0.0059 | 0.0059 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0291 | 0.3159 | 0.732 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.3159 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.1016 | 0.2355 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0221 | 0.0512 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.013 | 0.0331 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0157 | 0.0157 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0291 | 0.3159 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.013 | 0.0312 |
Trichomonas vaginalis | esterase, putative | 0.0074 | 0.0688 | 0.2179 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.013 | 0.0312 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0015 | 0.0027 | 0.0027 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0308 | 0.3348 | 1 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0018 | 0.0059 | 0.0059 |
Brugia malayi | MH1 domain containing protein | 0.0015 | 0.0021 | 0.0048 |
Schistosoma mansoni | dishevelled | 0.0018 | 0.0059 | 0.0059 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0196 | 0.2077 | 0.2077 |
Brugia malayi | N-terminal motif family protein | 0.037 | 0.4049 | 0.9384 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0648 | 0.1502 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0196 | 0.2077 | 0.2077 |
Trypanosoma brucei | polo-like protein kinase | 0.0291 | 0.3159 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0291 | 0.3159 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0196 | 0.2077 | 0.4814 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.013 | 0.0412 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0196 | 0.2077 | 0.2077 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0144 | 0.1489 | 0.4715 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0221 | 0.0221 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0308 | 0.3348 | 0.3348 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0027 | 0.0157 | 0.0157 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0308 | 0.3348 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0308 | 0.3348 | 1 |
Onchocerca volvulus | 0.0074 | 0.0688 | 0.17 | |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0221 | 0.0221 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0308 | 0.3348 | 0.3348 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0393 | 0.4315 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0157 | 0.0157 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0291 | 0.3159 | 0.3159 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0688 | 0.1595 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0688 | 0.1595 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0291 | 0.3159 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0181 | 0.1905 | 0.1905 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) [Related pubchem assays: 1379 ] | ChEMBL. | No reference |
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.