Detailed information for compound 1287941

Basic information

Technical information
  • TDR Targets ID: 1287941
  • Name: ethyl 1-[4-[1-(2-methoxyacetyl)piperidin-4-yl ]oxybenzoyl]piperidine-4-carboxylate
  • MW: 432.51 | Formula: C23H32N2O6
  • H donors: 0 H acceptors: 3 LogP: 2 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C1CCN(CC1)C(=O)c1ccc(cc1)OC1CCN(CC1)C(=O)COC
  • InChi: 1S/C23H32N2O6/c1-3-30-23(28)18-8-12-25(13-9-18)22(27)17-4-6-19(7-5-17)31-20-10-14-24(15-11-20)21(26)16-29-2/h4-7,18,20H,3,8-16H2,1-2H3
  • InChiKey: PIOSJAYDPZUQGO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ethyl 1-[4-[[1-(2-methoxyacetyl)-4-piperidyl]oxy]benzoyl]piperidine-4-carboxylate
  • 1-[[4-[[1-(2-methoxy-1-oxoethyl)-4-piperidinyl]oxy]phenyl]-oxomethyl]-4-piperidinecarboxylic acid ethyl ester
  • 1-[4-[[1-(2-methoxyacetyl)-4-piperidyl]oxy]benzoyl]isonipecotic acid ethyl ester
  • ethyl 1-[4-[1-(2-methoxyethanoyl)piperidin-4-yl]oxyphenyl]carbonylpiperidine-4-carboxylate

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens K(lysine) acetyltransferase 2A Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium knowlesi histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Babesia bovis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis Get druggable targets OG5_127781 All targets in OG5_127781
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium yoelii histone acetyltransferase GCN5-related Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Theileria parva histone acetyltransferase Gcn5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium falciparum histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium berghei histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Neospora caninum Bromodomain containing protein, related Get druggable targets OG5_127781 All targets in OG5_127781
Brugia malayi acetyltransferase, GNAT family protein Get druggable targets OG5_127781 All targets in OG5_127781
Neospora caninum hypothetical protein Get druggable targets OG5_127781 All targets in OG5_127781
Candida albicans bromodomain protein similar to S. cerevisiae GCN5 (YGR252W) histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Entamoeba histolytica acetyltransferase, GNAT family Get druggable targets OG5_127781 All targets in OG5_127781
Cryptosporidium parvum GCN5 like acetylase + bromodomain Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative Get druggable targets OG5_127781 All targets in OG5_127781
Loa Loa (eye worm) acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Toxoplasma gondii histone lysine acetyltransferase GCN5-B Get druggable targets OG5_127781 All targets in OG5_127781
Plasmodium vivax histone acetyltransferase GCN5, putative Get druggable targets OG5_127781 All targets in OG5_127781
Cryptosporidium hominis histone acetyltransferase Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma japonicum ko:K06062 p300/CBP-associated factor, putative Get druggable targets OG5_127781 All targets in OG5_127781
Giardia lamblia Histone acetyltransferase GCN5 Get druggable targets OG5_127781 All targets in OG5_127781
Toxoplasma gondii histone lysine acetyltransferase GCN5-A Get druggable targets OG5_127781 All targets in OG5_127781
Echinococcus granulosus histone acetyltransferase KAT2B Get druggable targets OG5_127781 All targets in OG5_127781
Trichomonas vaginalis bromodomain-containing protein, putative Get druggable targets OG5_127781 All targets in OG5_127781
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 Get druggable targets OG5_127781 All targets in OG5_127781
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0054 0.0104 0.0099
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0024 0.0026 0.0021
Brugia malayi Nuclear hormone receptor E75 0.0026 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.0062 0.0124 0.0235
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.003 0.0205
Mycobacterium leprae conserved hypothetical protein 0.0072 0.015 1
Brugia malayi Nuclear hormone receptor-like 1 0.0054 0.0104 0.0196
Echinococcus granulosus nuclear receptor nhr 48 0.0026 0.003 0.0025
Brugia malayi Isocitrate dehydrogenase 0.0048 0.0088 0.0166
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0072 0.1251
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0027 0.0034 0.0062
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0088 0.3112
Brugia malayi RNA binding protein 0.0323 0.0797 0.1531
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0054 0.0104 0.0196
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0024 0.0026 0.0021
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0431 0.0429
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0027 0.0078
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.002 0.0017 0.0744
Giardia lamblia Histone acetyltransferase GCN5 0.0076 0.016 0.3143
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.015 0.2932
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0017 0.0009 0.0081
Brugia malayi RasGEF domain containing protein 0.0019 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0072 0.015 0.0285
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Plasmodium falciparum small ubiquitin-related modifier 0.006 0.012 0.4098
Schistosoma mansoni importin beta-1 0.012 0.0272 0.027
Brugia malayi ecdysteroid receptor 0.0054 0.0104 0.0196
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0478 0.1722
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0767
Brugia malayi nuclear receptor RXR 0.0029 0.0038 0.007
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0024 0.0026 0.0023
Echinococcus multilocularis Smad4 0.0138 0.0321 0.0316
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0024 0.0026 0.0021
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0054 0.0104 0.0099
Mycobacterium leprae Polyketide synthase Pks13 0.0036 0.0058 0.3604
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0697 0.1758 0.1754
Mycobacterium ulcerans esterase/lipase LipP 0.0072 0.015 0.0533
Echinococcus granulosus importin subunit beta 1 0.012 0.0272 0.0268
Echinococcus granulosus beta LACTamase domain containing family member 0.0072 0.015 0.0145
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0083 0.0177 0.0607
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0068 0.014 0.4863
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0019 0.0014 0.0012
Schistosoma mansoni hypothetical protein 0.1183 0.3011 0.3009
Loa Loa (eye worm) MH2 domain-containing protein 0.0062 0.0124 0.0235
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Schistosoma mansoni hypothetical protein 0.0548 0.1374 0.1373
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0045
Echinococcus granulosus ubiquitin 0.0021 0.0019 0.0014
Loa Loa (eye worm) MH2 domain-containing protein 0.0138 0.0321 0.0614
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0062
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0023 0.0024 0.0229
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0024 0.0026 0.0023
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0019 0.0015 0.0033
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Toxoplasma gondii HEAT repeat-containing protein 0.0023 0.0023 0.0665
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.0238 0.8677
Schistosoma mansoni Smad4 0.0062 0.0124 0.0122
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0026 0.0031 0.1734
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0026 0.0031 0.1734
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Schistosoma mansoni z-protein (S1r protein) 0.0027 0.0034 0.0032
Schistosoma mansoni transcription factor LCR-F1 0.0374 0.0927 0.0926
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0157 0.0369 0.0367
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Echinococcus multilocularis ubiquitin specific protease 41 0.0157 0.0369 0.0364
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) hepatopoietin HPO2 0.0068 0.014 0.0265
Loa Loa (eye worm) kap beta 3 protein 0.0023 0.0023 0.004
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0431 0.0429
Plasmodium vivax small ubiquitin-related modifier, putative 0.006 0.012 0.4098
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0045
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0076 0.0161 0.0156
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0104 0.0099
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0054 0.0104 0.0196
Schistosoma mansoni smad 0.0062 0.0124 0.0122
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Echinococcus granulosus TGF beta signal transducer SmadC 0.0138 0.0321 0.0316
Onchocerca volvulus 0.003 0.0041 0.0285
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0088 0.0191 0.6857
Leishmania major hypothetical protein, conserved 0.0106 0.0238 0.4836
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Brugia malayi TAR-binding protein 0.0323 0.0797 0.1531
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0024 0.0026 0.0043
Brugia malayi MH1 domain containing protein 0.0138 0.0321 0.0614
Entamoeba histolytica hypothetical protein 0.0019 0.0014 0.0003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Onchocerca volvulus 0.0019 0.0014 0.0088
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0062
Mycobacterium tuberculosis Conserved protein 0.0072 0.015 0.1305
Brugia malayi orphan nuclear receptor NR2E1 0.0026 0.003 0.0054
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0024 0.0026 0.0451
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0068 0.014 0.271
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0014 0.0023
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0024 0.0026 0.0021
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0181 0.0431 0.0426
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Entamoeba histolytica hypothetical protein 0.0374 0.0927 1
Echinococcus multilocularis regulator of G protein signaling 7 0.0027 0.0034 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0054 0.0104 0.0196
Loa Loa (eye worm) hypothetical protein 0.0072 0.015 0.0285
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0101 0.0223 0.0426
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0072 0.0135
Trichomonas vaginalis ubiquitin specific protease, putative 0.0024 0.0026 0.0043
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0088 0.0191 0.6857
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0088 0.0191 0.3822
Echinococcus multilocularis aryl hydrocarbon receptor 0.0026 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.0549 0.1378 0.265
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0024 0.0027 0.0234
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.015 0.0148
Toxoplasma gondii LsmAD domain-containing protein 0.0106 0.0238 0.8721
Trichomonas vaginalis DNA polymerase eta, putative 0.0042 0.0072 0.0215
Trichomonas vaginalis rotamase, putative 0.0101 0.0223 0.0778
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0042 0.0072 0.0067
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Schistosoma mansoni thyroid hormone receptor 0.0054 0.0104 0.0102
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0548 0.1374 0.2642
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0181 0.0431 0.0426
Trypanosoma brucei small ubiquitin-related modifier 0.006 0.012 0.2284
Mycobacterium tuberculosis Conserved hypothetical protein 0.0042 0.0072 0.0626
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0024 0.0026 0.0023
Toxoplasma gondii ABC1 family protein 0.0072 0.015 0.5417
Echinococcus granulosus aryl hydrocarbon receptor 0.0026 0.003 0.0026
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0038 0.007
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Echinococcus multilocularis high affinity choline transporter 1 0.0693 0.1748 0.1744
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0196
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Onchocerca volvulus 0.0072 0.015 0.1074
Toxoplasma gondii type I fatty acid synthase, putative 0.0017 0.0009 0.0147
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.003 0.0025
Trypanosoma brucei Importin-beta N-terminal domain/HEAT-like repeat, putative 0.0023 0.0023 0.0193
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0029 0.0038 0.007
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0054 0.0104 0.0196
Brugia malayi steroid hormone receptor 0.0054 0.0104 0.0196
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0024 0.0027 0.1465
Entamoeba histolytica hypothetical protein 0.0374 0.0927 1
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Brugia malayi hypothetical protein 0.0026 0.003 0.0054
Brugia malayi beta-lactamase family protein 0.0072 0.015 0.0285
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0767
Trichomonas vaginalis ras GTP exchange factor, putative 0.0019 0.0014 0.0001
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0048 0.0088 0.1603
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0323 0.0797 0.0795
Echinococcus granulosus snurportin 1 0.1277 0.3252 0.3248
Echinococcus granulosus son of sevenless 1 0.0019 0.0014 0.0009
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0042 0.0072 0.0215
Onchocerca volvulus 0.0042 0.0073 0.0516
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0196
Brugia malayi regulator of G-protein signaling egl-10 0.0027 0.0034 0.0062
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0072 0.0245
Loa Loa (eye worm) glutaminase 0.1066 0.2709 0.5212
Trypanosoma cruzi small ubiquitin protein, putative 0.006 0.012 0.2284
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0024 0.0026 0.0021
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0138 0.0321 0.0316
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0026 0.003 0.0055
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0024 0.0026 0.0128
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Loa Loa (eye worm) hypothetical protein 0.0106 0.0238 0.0455
Brugia malayi ecdysone receptor 0.0026 0.003 0.0054
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0029 0.0038 0.0036
Schistosoma mansoni smad1 5 8 and 0.0138 0.0321 0.0319
Echinococcus multilocularis segment polarity protein dishevelled 0.0027 0.0034 0.0029
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0024 0.0026 0.0767
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Loa Loa (eye worm) glutaminase 2 0.1066 0.2709 0.5212
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0026 0.0031 0.0092
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0045
Loa Loa (eye worm) steroid hormone receptor 0.0054 0.0104 0.0196
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0024 0.0026 0.0021
Onchocerca volvulus 0.0072 0.015 0.1074
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis chromobox protein, putative 0.0041 0.007 0.0208
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0024 0.0026 0.0021
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0019 0.0015 0.062
Trichomonas vaginalis glutaminase, putative 0.1066 0.2709 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0139 0.0264
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0031 0.0043 0.0634
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0042 0.0072 0.1251
Onchocerca volvulus Protein cycle homolog 0.0018 0.0011 0.0063
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0072 0.1251
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0024 0.0026 0.0251
Toxoplasma gondii ubiquitin-specific protease USP4 0.0024 0.0026 0.0767
Schistosoma mansoni chromobox protein 0.0068 0.0139 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0039 0.0533
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0323 0.0797 0.0795
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0072 0.015 0.1305
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0157 0.0369 0.765
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0549 0.1378 1
Brugia malayi Smad1 0.0138 0.0321 0.0614
Mycobacterium ulcerans hypothetical protein 0.0072 0.015 0.0533
Echinococcus multilocularis beta LACTamase domain containing family member 0.0072 0.015 0.0145
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Brugia malayi nuclear hormone receptor family member nhr-6 0.0026 0.003 0.0054
Brugia malayi MH2 domain containing protein 0.0138 0.0321 0.0614
Plasmodium vivax ubiquitin specific protease, putative 0.0024 0.0026 0.0451
Loa Loa (eye worm) hypothetical protein 0.0693 0.1748 0.3361
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0027 0.0078
Loa Loa (eye worm) SMO-1 protein 0.006 0.012 0.0227
Trichomonas vaginalis ubiquitin specific protease, putative 0.0024 0.0026 0.0043
Echinococcus multilocularis Protein son of sevenless 0.0019 0.0014 0.0009
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Leishmania major DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Schistosoma mansoni Smad4 0.0138 0.0321 0.0319
Schistosoma mansoni RAR-like nuclear receptor 0.0054 0.0104 0.0102
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0219 0.076
Loa Loa (eye worm) RNA binding protein 0.0323 0.0797 0.1531
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0054 0.0104 0.0196
Loa Loa (eye worm) RasGEF domain-containing protein 0.0019 0.0014 0.0023
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0024 0.0026 0.0023
Brugia malayi isocitrate dehydrogenase 0.0048 0.0088 0.0166
Echinococcus granulosus solute carrier family 5 0.0076 0.0161 0.0156
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0026 0.003 0.0028
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0088 0.0191 0.3822
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0054 0.0104 0.0196
Echinococcus granulosus transportin 1 0.0023 0.0023 0.0018
Brugia malayi mothers against decapentaplegic homolog 3 0.0062 0.0124 0.0235
Schistosoma mansoni nuclear receptor 0.0026 0.003 0.0028
Brugia malayi N-terminal motif family protein 0.0019 0.0014 0.0023
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0024 0.0026 0.0451
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0076 0.0161 0.0156
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0088 0.0083
Entamoeba histolytica hypothetical protein 0.0021 0.0019 0.0055
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Leishmania major DNA polymerase eta, putative 0.0042 0.0072 0.1251
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Toxoplasma gondii HEAT repeat-containing protein 0.0023 0.0023 0.0665
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0767
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.015 0.0505
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0181 0.0431 0.0826
Brugia malayi nuclear hormone receptor family member odr-7 0.0026 0.003 0.0054
Brugia malayi MH1 domain containing protein 0.0077 0.0162 0.0307
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0076 0.0161 0.5842
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Mycobacterium leprae Probable polyketide synthase Pks1 0.0026 0.0031 0.1734
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0767
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0478 0.1722
Mycobacterium tuberculosis Probable hydrolase 0.0072 0.015 0.1305
Schistosoma mansoni hypothetical protein 0.0048 0.0087 0.0085
Onchocerca volvulus Fatty acid synthase homolog 0.0044 0.0077 0.0544
Trypanosoma brucei polo-like protein kinase 0.0199 0.0478 1
Schistosoma mansoni gabp alpha 0.0071 0.0147 0.0145
Brugia malayi hypothetical protein 0.0029 0.0038 0.007
Brugia malayi MH1 domain containing protein 0.0138 0.0321 0.0614
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0019 0.0014 0.0009
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0101 0.0223 0.0426
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0026 0.0031 0.0268
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0024 0.0026 0.0251
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0024 0.0026 0.0021
Schistosoma mansoni calpain-7 (C02 family) 0.0024 0.0026 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0024 0.0026 0.0023
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0054 0.0104 0.0099
Echinococcus granulosus Pleckstrin G protein interacting region 0.0027 0.0034 0.0029
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.1277 0.3252 0.6257
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0024 0.0026 0.0451
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0088 0.0191 0.3822
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0019 0.0014 0.0009
Brugia malayi hypothetical protein 0.0069 0.0141 0.0268
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Onchocerca volvulus 0.0072 0.015 0.1074
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0097 0.0214 0.0744
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0024 0.0026 0.0023
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0027 0.0034 0.0062
Trypanosoma brucei unspecified product 0.0029 0.0039 0.0533
Loa Loa (eye worm) fatty acid synthase 0.0024 0.0026 0.0046
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Brugia malayi nuclear receptor NHR-88 0.0054 0.0104 0.0196
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0054 0.0104 0.0099
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Entamoeba histolytica acetyltransferase, GNAT family 0.0076 0.016 0.1596
Echinococcus granulosus chromobox protein 1 0.0068 0.0139 0.0134
Loa Loa (eye worm) hypothetical protein 0.0029 0.0038 0.007
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0045
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0157 0.0369 0.1317
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Schistosoma mansoni ran 0.0088 0.0191 0.0189
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0045
Brugia malayi acetyltransferase, GNAT family protein 0.0281 0.0688 0.1322
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0054 0.0104 0.074
Brugia malayi Augmenter of liver regeneration 0.0068 0.014 0.0265
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0026 0.003 0.0025
Loa Loa (eye worm) hypothetical protein 0.0029 0.0038 0.007
Brugia malayi Protein kinase domain containing protein 0.0016 0.0005 0.0005
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Toxoplasma gondii isocitrate dehydrogenase 0.0048 0.0088 0.3112
Loa Loa (eye worm) MH2 domain-containing protein 0.2032 0.5196 1
Giardia lamblia DUB-1 0.0024 0.0026 0.0251
Brugia malayi nuclear receptor RXR 0.0026 0.003 0.0054
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0054 0.0104 0.0102
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0199 0.0478 1
Schistosoma mansoni ap endonuclease 0.0019 0.0014 0.0012
Schistosoma mansoni hypothetical protein 0.0548 0.1374 0.1373
Echinococcus granulosus sodium:myo inositol cotransporter 0.0076 0.0161 0.0156
Brugia malayi RasGEF domain containing protein 0.0019 0.0014 0.0023
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0767
Schistosoma mansoni ap endonuclease 0.0019 0.0014 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0157 0.0369 0.1317
Echinococcus multilocularis segment polarity protein dishevelled 0.0027 0.0034 0.0029
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0024 0.0026 0.0023
Trypanosoma cruzi small ubiquitin protein, putative 0.006 0.012 0.2284
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trypanosoma cruzi hypothetical protein 0.0019 0.0014 0.0007
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0036 0.0058 0.0503
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0032
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0281 0.0688 0.0687
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0039 0.0533
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.006 0.012 0.0118
Brugia malayi Heterochromatin protein 1 0.0068 0.0139 0.0264
Trichomonas vaginalis ubiquitin specific protease, putative 0.0024 0.0026 0.0043
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0767
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus granulosus regulator of G protein signaling 7 0.0027 0.0034 0.0029
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0083 0.0177 0.6325
Brugia malayi conserved hypotetical protein 0.0026 0.003 0.0054
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0088 0.0191 0.0364
Schistosoma mansoni glutaminase 0.1066 0.2709 0.2707
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0088 0.0083
Brugia malayi ubiquitin specific protease 14 0.0024 0.0026 0.0045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0045
Echinococcus multilocularis mothers against decapentaplegic 5 0.0138 0.0321 0.0316
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Echinococcus granulosus GPCR family 2 0.0548 0.1374 0.137
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0196
Schistosoma mansoni kinase 0.0101 0.0225 0.0223
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0024 0.0026 0.0021
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0024 0.0027 0.1465
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0451
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0088 0.1603
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0181 0.0431 0.0426
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0019 0.0019
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0031 0.0043 0.0634
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Onchocerca volvulus 0.0023 0.0023 0.0151
Echinococcus multilocularis importin subunit beta 1 0.012 0.0272 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Mycobacterium tuberculosis Probable lipase LipE 0.0072 0.015 0.1305
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0024 0.0026 0.0767
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0068 0.014 0.0135
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0054 0.0104 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0026 0.003 0.0205
Brugia malayi beta-lactamase family protein 0.0072 0.015 0.0285
Echinococcus multilocularis ecdysone induced protein 78C 0.0054 0.0104 0.0099
Plasmodium falciparum ubiquitin specific protease, putative 0.0024 0.0026 0.0451
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Echinococcus multilocularis regulator of G protein signaling 7 0.0027 0.0034 0.0029
Trichomonas vaginalis esterase, putative 0.0072 0.015 0.0505
Mycobacterium ulcerans thioesterase TesA 0.002 0.0017 0.004
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0014 0.003
Mycobacterium tuberculosis Probable thioesterase TesA 0.002 0.0017 0.0144
Loa Loa (eye worm) fli-1 protein 0.0215 0.0519 0.0995
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Echinococcus granulosus FTZ F1 alpha 0.0054 0.0104 0.0099
Mycobacterium tuberculosis Probable esterase LipL 0.0072 0.015 0.1305
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0031 0.0043 0.0634
Loa Loa (eye worm) MH1 domain-containing protein 0.0062 0.0124 0.0235
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0026 0.003 0.0054
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0045
Brugia malayi aryl hydrocarbon receptor nuclear translocator protein, putative 0.0018 0.0011 0.0017
Plasmodium vivax importin-beta 2, putative 0.012 0.0272 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis ras GTP exchange factor, son of sevenless, putative 0.0019 0.0014 0.0001
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0199 0.0478 0.0473
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0024 0.0026 0.0451
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.015 0.0505
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus granulosus tar DNA binding protein 0.0323 0.0797 0.0792
Loa Loa (eye worm) hypothetical protein 0.0548 0.1374 0.2642
Echinococcus granulosus ubiquitin specific peptidase c family 0.0024 0.0026 0.0021
Loa Loa (eye worm) beta-lactamase 0.0072 0.015 0.0285
Onchocerca volvulus Bile acid receptor homolog 0.0054 0.0104 0.074
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0139 0.0464
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0478 0.1722
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Onchocerca volvulus 0.0076 0.0161 0.1157
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0024 0.0026 0.0023
Loa Loa (eye worm) nuclear factor I 0.0077 0.0162 0.0307
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Echinococcus multilocularis mothers against decapentaplegic 2 0.0062 0.0124 0.0119
Brugia malayi Steroid receptor seven-up type 2 0.0054 0.0104 0.0196
Echinococcus multilocularis importin 5 0.0023 0.0023 0.0018
Echinococcus granulosus mothers against decapentaplegic 2 0.0062 0.0124 0.0119
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0045
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0019 0.0015 0.0033
Schistosoma mansoni aryl hydrocarbon receptor nuclear translocator homolog (darnt) 0.0018 0.0011 0.0009
Trichomonas vaginalis D-aminoacylase, putative 0.0072 0.015 0.0505
Brugia malayi hypothetical protein 0.0026 0.003 0.0054
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0029 0.0038 0.0033
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Giardia lamblia Sentrin 0.006 0.012 0.2284
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0018 0.0011 0.0017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Brugia malayi ImpB/MucB/SamB family protein 0.0042 0.0072 0.0135
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0014 0.0009
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0157 0.0369 0.765
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus multilocularis ubiquitin 0.0021 0.0019 0.0014
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.003 0.0025
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0024 0.0026 0.0043
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0027 0.0034 0.0233
Trichomonas vaginalis bromodomain-containing protein, putative 0.0083 0.0177 0.0607
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0054 0.0104 0.0196
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0024 0.0026 0.0128
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.003 0.0025
Brugia malayi hypothetical protein 0.0027 0.0034 0.0062
Trichomonas vaginalis rotamase, putative 0.0098 0.0217 0.0755
Echinococcus granulosus regulator of G protein signaling 7 0.0027 0.0034 0.0029
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0026 0.003 0.0025
Entamoeba histolytica HEAT repeat domain containing protein 0.0023 0.0023 0.0098
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.0031 0.0092
Loa Loa (eye worm) hypothetical protein 0.0072 0.015 0.0285
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0083 0.0177 0.6447
Brugia malayi Ets-domain containing protein 0.0071 0.0147 0.0279
Schistosoma mansoni hypothetical protein 0.0374 0.0927 0.0926
Schistosoma mansoni retinoic acid receptor RXR 0.0054 0.0104 0.0102
Echinococcus granulosus Smad4 0.0138 0.0321 0.0316
Echinococcus multilocularis nuclear receptor nhr 48 0.0026 0.003 0.0025
Onchocerca volvulus 0.0026 0.003 0.0205
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Brugia malayi photoreceptor-specific nuclear receptor 0.1074 0.2729 0.5251
Onchocerca volvulus 0.0021 0.0019 0.0122
Mycobacterium ulcerans beta-lactamase 0.0072 0.015 0.0533
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0045
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0026 0.003 0.0025
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0157 0.0369 0.765
Trichomonas vaginalis conserved hypothetical protein 0.0157 0.0369 0.1317
Onchocerca volvulus 0.0026 0.003 0.0205
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0068 0.014 0.271
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Entamoeba histolytica ubiquitin like protein 0.006 0.012 0.116
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Echinococcus multilocularis chromobox protein 1 0.0068 0.0139 0.0134
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0068 0.014 0.271
Echinococcus granulosus smad 0.0138 0.0321 0.0316
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0104 0.0099
Brugia malayi MH2 domain containing protein 0.2032 0.5196 1
Entamoeba histolytica Ran family GTPase 0.0088 0.0191 0.1941
Loa Loa (eye worm) hypothetical protein 0.0027 0.0034 0.0062
Mycobacterium tuberculosis Conserved protein 0.0072 0.015 0.1305
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0024 0.0026 0.0021
Schistosoma mansoni peptidase 0.0024 0.0027 0.0025
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Schistosoma mansoni Smad4 0.0062 0.0124 0.0122
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.015 0.2932
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0026 0.003 0.0054
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0003
Schistosoma mansoni high-affinity choline transporter 0.0693 0.1748 0.1746
Trypanosoma brucei unspecified product 0.0042 0.0072 0.1251
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0042 0.0072 0.0067
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0098 0.0217 0.4386
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Echinococcus granulosus segment polarity protein dishevelled 0.0027 0.0034 0.0029
Brugia malayi Latrophilin receptor protein 2 0.0548 0.1374 0.2642
Echinococcus granulosus dna polymerase kappa 0.0042 0.0072 0.0067
Leishmania major hypothetical protein, conserved 0.0023 0.0023 0.0193
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0019 0.0014 0.0012
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0045
Echinococcus multilocularis expressed protein 0.0024 0.0026 0.0021
Trypanosoma brucei DNA polymerase IV, putative 0.0042 0.0072 0.1251
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Schistosoma mansoni smad 0.0138 0.0321 0.0319
Loa Loa (eye worm) acetyltransferase 0.0281 0.0688 0.1322
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0196
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0048 0.0088 0.2876
Schistosoma mansoni inositol transporter 0.0076 0.0161 0.0159
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.003 0.0025
Schistosoma mansoni tar DNA-binding protein 0.0323 0.0797 0.0795
Brugia malayi MH2 domain containing protein 0.0138 0.0321 0.0614
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Brugia malayi hypothetical protein 0.0021 0.0019 0.0032
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0147 0.0142
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0098 0.0217 0.4386
Trichomonas vaginalis conserved hypothetical protein 0.0101 0.0223 0.0778
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.007 0.0492
Schistosoma mansoni rotamase 0.0101 0.0223 0.0221
Trichomonas vaginalis chromobox protein, putative 0.0041 0.007 0.0208
Echinococcus multilocularis son of sevenless 1 0.0019 0.0014 0.0009
Mycobacterium ulcerans DNA polymerase IV 0.0042 0.0072 0.0245
Trypanosoma brucei PAB1-binding protein , putative 0.0106 0.0238 0.4836
Trypanosoma brucei DNA polymerase eta, putative 0.0042 0.0072 0.1251
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Echinococcus multilocularis snurportin 1 0.1277 0.3252 0.3248
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0128
Brugia malayi Fli-1 protein 0.0215 0.0519 0.0995
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.0238 0.4836
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0024 0.0027 0.0048
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0097 0.0214 0.0744
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Loa Loa (eye worm) hypothetical protein 0.1183 0.3011 0.5793
Entamoeba histolytica hypothetical protein 0.0374 0.0927 1
Leishmania major GTP-binding protein, putative 0.0088 0.0191 0.3822
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0024 0.0026 0.0021
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0281 0.0688 0.0684
Brugia malayi Calcitonin receptor-like protein seb-1 0.1731 0.4421 0.8507
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0181 0.0431 0.0826
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0048 0.0088 0.0083
Trypanosoma cruzi PAB1-binding protein , putative 0.0106 0.0238 0.4836
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trypanosoma cruzi hypothetical protein 0.0019 0.0014 0.0007
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0181 0.0431 0.0426
Echinococcus granulosus mothers against decapentaplegic 5 0.0138 0.0321 0.0316
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0048 0.0088 0.2876
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0024 0.0026 0.0021
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0024 0.0026 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus granulosus translational activator gcn1 0.0023 0.0023 0.0018
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0024 0.0026 0.0021
Brugia malayi Nuclear hormone receptor-like 1 0.0029 0.0038 0.007
Toxoplasma gondii exonuclease III APE 0.0019 0.0014 0.0331
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0023 0.004
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Echinococcus granulosus sodium:glucose cotransporter 2 0.0076 0.0161 0.0156
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0548 0.1374 0.137
Schistosoma mansoni ets-related 0.0215 0.0519 0.0517
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0072 0.015 0.0533
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0024 0.0026 0.0021
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0024 0.0026 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus multilocularis GPCR, family 2 0.0548 0.1374 0.137
Trypanosoma brucei importin beta-1 subunit, putative 0.012 0.0272 0.5574
Schistosoma mansoni hypothetical protein 0.1277 0.3252 0.325
Toxoplasma gondii hypothetical protein 0.0027 0.0034 0.1089
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0024 0.0027 0.0234
Echinococcus granulosus dna polymerase eta 0.0042 0.0072 0.0067
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0068 0.014 0.0135
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0088 0.1603
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0019 0.0014 0.0012
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0139 0.0464
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0098 0.0217 0.2228
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Echinococcus granulosus Small ubiquitin modifier 2 0.006 0.012 0.0115
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0076 0.0161 0.0156
Leishmania major small ubiquitin protein, putative 0.006 0.012 0.2284
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0024 0.0026 0.0021
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0157 0.0369 0.765
Brugia malayi nuclear receptor NHR-88 0.0026 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Brugia malayi N-terminal motif family protein 0.0019 0.0014 0.0023
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0042 0.0072 0.0135
Mycobacterium ulcerans polyketide synthase 0.0024 0.0027 0.0078
Echinococcus multilocularis transportin 1 0.0023 0.0023 0.0018
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0138 0.0321 0.0319
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0048 0.0088 0.1603
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0024 0.0026 0.0021
Schistosoma mansoni terminal deoxycytidyl transferase 0.0042 0.0072 0.007
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Toxoplasma gondii Erv1 / Alr family protein 0.0068 0.014 0.5033
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0024 0.0026 0.0451
Schistosoma mansoni nuclear hormone receptor 0.0026 0.003 0.0028
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0054 0.0104 0.0102
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0042 0.0072 0.007
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Schistosoma mansoni sodium/solute symporter 0.0076 0.0161 0.0159
Brugia malayi RNA recognition motif domain containing protein 0.0323 0.0797 0.1531
Onchocerca volvulus 0.0016 0.0005 0.0021
Brugia malayi Nuclear hormone receptor E75 0.0026 0.003 0.0054
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0041 0.0069 0.0129
Trichomonas vaginalis ran, putative 0.0088 0.0191 0.0658
Entamoeba histolytica hypothetical protein 0.0097 0.0214 0.2193
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus multilocularis thyroid hormone receptor alpha 0.0054 0.0104 0.0099
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0024 0.0026 0.0045
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0024 0.0026 0.0023
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0072 0.015 0.1305
Toxoplasma gondii Erv1 / Alr family protein 0.0068 0.014 0.5033
Echinococcus multilocularis translational activator gcn1 0.0023 0.0023 0.0018
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0767
Loa Loa (eye worm) hypothetical protein 0.0072 0.015 0.0285
Echinococcus granulosus Nuclear hormone receptor HR96 0.0026 0.003 0.0025
Loa Loa (eye worm) hypothetical protein 0.0076 0.0161 0.0307
Onchocerca volvulus Protein ultraspiracle homolog 0.0054 0.0104 0.074
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0024 0.0026 0.0023
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0024 0.0026 0.0023
Echinococcus multilocularis solute carrier family 5 0.0076 0.0161 0.0156
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0024 0.0026 0.0451
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0147 0.0142
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0076 0.0161 0.0156
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0024 0.0026 0.0021
Brugia malayi tailless protein 0.0026 0.003 0.0054
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0045
Echinococcus multilocularis isocitrate dehydrogenase 0.0048 0.0088 0.0083
Schistosoma mansoni smad1 5 8 and 0.0138 0.0321 0.0319
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0024 0.0026 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus granulosus importin 5 0.0023 0.0023 0.0018
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0019 0.0014 0.0009
Loa Loa (eye worm) latrophilin receptor protein 2 0.0548 0.1374 0.2642
Loa Loa (eye worm) DR-78 0.0026 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.188 0.4804 0.9247
Plasmodium falciparum histone acetyltransferase GCN5 0.0076 0.016 0.5639
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0054 0.0104 0.0099
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) DIX domain-containing protein 0.0027 0.0034 0.0062
Schistosoma mansoni chromobox protein 0.0068 0.0139 0.0137
Trichomonas vaginalis ubiquitin, putative 0.0021 0.0019 0.0019
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0024 0.0026 0.0045
Loa Loa (eye worm) hypothetical protein 0.0072 0.015 0.0285
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0024 0.0026 0.0021
Echinococcus granulosus ras GTP exchange factor 0.0019 0.0014 0.0009
Brugia malayi chromobox protein homolog 3 0.0038 0.0062 0.0116
Schistosoma mansoni nuclear receptor 0.0026 0.003 0.0028
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Brugia malayi nuclear receptor NHR-67 0.0026 0.003 0.0054
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Mycobacterium tuberculosis Probable lipase LipD 0.0072 0.015 0.1305
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0024 0.0026 0.0021
Schistosoma mansoni dishevelled 0.0027 0.0034 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.0104 0.0196
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0019 0.0014 0.0088
Brugia malayi RNA, U transporter 1 0.034 0.084 0.1614
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0024 0.0026 0.0451
Loa Loa (eye worm) isocitrate dehydrogenase 0.0048 0.0088 0.0166
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0697 0.1758 0.1754
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0088 0.0191 0.6961
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0034 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.0104 0.0196
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Toxoplasma gondii HEAT repeat-containing protein 0.012 0.0272 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Loa Loa (eye worm) hypothetical protein 0.0077 0.0162 0.0307
Schistosoma mansoni dishevelled 0.0027 0.0034 0.0032
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.006 0.012 0.0393
Plasmodium vivax transportin, putative 0.0023 0.0023 0.0346
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0024 0.0026 0.0021
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Trichomonas vaginalis CAMK family protein kinase 0.0099 0.0219 0.076
Mycobacterium ulcerans polyketide synthase Pks13 0.0036 0.0058 0.0192
Echinococcus multilocularis smad 0.0138 0.0321 0.0316
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Echinococcus granulosus ecdysone induced protein 78C 0.0054 0.0104 0.0099
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Loa Loa (eye worm) Smad1 0.0138 0.0321 0.0614
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0548 0.1374 0.137
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0072 0.015 0.0285
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0031 0.0043 0.0634
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0017
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0048 0.0088 0.0768
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Brugia malayi aryl hydrocarbon receptor AHR-1 0.0018 0.0011 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0048 0.0087 0.0082
Schistosoma mansoni hypothetical protein 0.0016 0.0005 0.0003
Onchocerca volvulus 0.0024 0.0026 0.0171
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0024 0.0026 0.0045
Trichomonas vaginalis ras GTP exchange factor, putative 0.0019 0.0014 0.0001
Brugia malayi hypothetical protein 0.0024 0.0026 0.0045
Schistosoma mansoni coup transcription factor 0.0054 0.0104 0.0102
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0029 0.0038 0.0033
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.188 0.4804 0.9247
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0767
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0374 0.0927 0.0923
Brugia malayi kap beta 3 protein 0.0023 0.0023 0.004
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0045
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Loa Loa (eye worm) hypothetical protein 0.0029 0.0038 0.007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Plasmodium falciparum ataxin-2 like protein, putative 0.0106 0.0238 0.8677
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0039 0.0533
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Mycobacterium ulcerans lipase LipD 0.0072 0.015 0.0533
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0024 0.0026 0.0021
Schistosoma mansoni nuclear hormone receptor 0.0026 0.003 0.0028
Echinococcus multilocularis Small ubiquitin modifier 2 0.006 0.012 0.0115
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0062 0.018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0054 0.0104 0.0196
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.003 0.0041 0.0075
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0027 0.0034 0.0029
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0374 0.0927 0.0923
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0072 0.015 0.1305
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0054 0.0104 0.0102
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis hypothetical protein 0.0023 0.0023 0.0033
Loa Loa (eye worm) nuclear receptor NHR-67 0.0026 0.003 0.0054
Toxoplasma gondii peptidylprolyl isomerase 0.0098 0.0217 0.794
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0026 0.0451
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0196
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Brugia malayi hypothetical protein 0.0018 0.0011 0.0017
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0027 0.0034 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0062 0.018
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0024 0.0026 0.0021
Schistosoma mansoni dep domain containing protein 0.0027 0.0034 0.0032
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0088 0.0191 0.3822
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0054 0.0104 0.0099
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Entamoeba histolytica deoxycytidyl transferase, putative 0.0042 0.0072 0.0635
Schistosoma mansoni zinc finger protein 0.0026 0.003 0.0028
Echinococcus granulosus Protein son of sevenless 0.0019 0.0014 0.0009
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0024 0.0026 0.0767
Brugia malayi MH1 domain containing protein 0.0077 0.0162 0.0307
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Leishmania major protein kinase, putative 0.002 0.0017 0.0058
Trypanosoma cruzi DNA polymerase eta, putative 0.0042 0.0072 0.1251
Schistosoma mansoni smad1 5 8 and 0.0138 0.0321 0.0319
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0157 0.0369 0.765
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0054 0.0104 0.0102
Mycobacterium leprae Probable lipase LipE 0.0072 0.015 1
Onchocerca volvulus 0.0027 0.0034 0.0233
Schistosoma mansoni hypothetical protein 0.0024 0.0026 0.0023
Mycobacterium ulcerans polyketide synthase 0.0026 0.0031 0.0092
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0045
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0024 0.0026 0.0021
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0024 0.0026 0.0021
Leishmania major importin beta-1 subunit, putative 0.0097 0.0214 0.4319
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0024 0.0026 0.0023
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Plasmodium vivax hypothetical protein, conserved 0.0072 0.015 0.526
Echinococcus granulosus expressed protein 0.0101 0.0223 0.0219
Loa Loa (eye worm) hypothetical protein 0.0019 0.0014 0.0023
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0024 0.0026 0.0021
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0027 0.0034 0.0062
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0031 0.0043 0.1431
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0045
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0024 0.0026 0.0023
Leishmania major hypothetical protein, conserved 0.0068 0.014 0.271
Schistosoma mansoni hypothetical protein 0.0548 0.1374 0.1373
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0054 0.0104 0.0196
Trypanosoma cruzi polo-like protein kinase, putative 0.0199 0.0478 1
Brugia malayi Ubiquitin-like protein SMT3 0.006 0.012 0.0227
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0023 0.0025 0.0218
Loa Loa (eye worm) hypothetical protein 0.0157 0.0369 0.0706
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0068 0.014 0.4863
Trichomonas vaginalis importin beta-1, putative 0.0097 0.0214 0.0744
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0098 0.0217 0.4386
Plasmodium vivax ataxin-2 like protein, putative 0.0106 0.0238 0.8677
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0024 0.0026 0.0043
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Brugia malayi RasGEF domain containing protein 0.0019 0.0014 0.0023
Loa Loa (eye worm) RasGEF domain-containing protein 0.0019 0.0014 0.0023
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Echinococcus granulosus high affinity choline transporter 1 0.0693 0.1748 0.1744
Echinococcus multilocularis chromobox protein 1 0.0068 0.0139 0.0134
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0017
Echinococcus granulosus GTP binding nuclear protein Ran 0.0088 0.0191 0.0186
Loa Loa (eye worm) MH1 domain-containing protein 0.0138 0.0321 0.0614
Entamoeba histolytica hypothetical protein 0.0024 0.0026 0.0128
Echinococcus granulosus mothers against decapentaplegic 6 0.0062 0.0124 0.0119
Schistosoma mansoni calpain-7 (C02 family) 0.0024 0.0026 0.0023
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0157 0.0369 0.0367
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0478 0.1722
Brugia malayi Ets-domain containing protein 0.0071 0.0147 0.0279
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0019 0.0014 0.0012
Onchocerca volvulus 0.0016 0.0005 0.0021
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0023 0.0023 0.004
Brugia malayi Importin beta-1 subunit 0.012 0.0272 0.0521
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0024 0.0026 0.0021
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0157 0.0369 0.0364
Echinococcus granulosus ubiquitin specific protease 41 0.0157 0.0369 0.0364
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Trypanosoma brucei unspecified product 0.0029 0.0039 0.0533
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0024 0.0026 0.0021
Mycobacterium ulcerans thioesterase 0.002 0.0017 0.004
Loa Loa (eye worm) importin-beta domain-containing protein 0.0023 0.0023 0.004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0045
Entamoeba histolytica hypothetical protein 0.0374 0.0927 1
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0024 0.0027 0.0234
Schistosoma mansoni nuclear hormone receptor 0.0054 0.0104 0.0102
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0323 0.0797 0.1531
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0054 0.0104 0.0099
Brugia malayi hypothetical protein 0.0016 0.0005 0.0005
Schistosoma mansoni ras GTP exchange factor 0.0019 0.0014 0.0012
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0048 0.0088 0.0083
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Brugia malayi hypothetical protein 0.0018 0.0011 0.0017
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0026 0.0031 0.0268
Toxoplasma gondii hypothetical protein 0.0024 0.0026 0.0767
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0054 0.0104 0.0196
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Loa Loa (eye worm) hypothetical protein 0.0029 0.0038 0.007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0024 0.0026 0.0021
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0054 0.0104 0.0099
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0024 0.0026 0.0251
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0026 0.003 0.0028
Loa Loa (eye worm) RasGEF domain-containing protein 0.0019 0.0014 0.0023
Mycobacterium ulcerans glutaminase 0.1066 0.2709 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0024 0.0026 0.0021
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0014 0.5
Brugia malayi DIX domain containing protein 0.0027 0.0034 0.0062
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0196
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Schistosoma mansoni camp-dependent rap1 guanine-nucleotide exchange factor 0.0018 0.0012 0.001
Schistosoma mansoni steroid hormone receptor ad4bp 0.0054 0.0104 0.0102
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0048 0.0088 0.0086
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0014 0.0121
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0023 0.0023 0.0199
Loa Loa (eye worm) hypothetical protein 0.0042 0.0072 0.0135
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0478 0.1722
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0088 0.0191 0.0186
Loa Loa (eye worm) TK/ALK protein kinase 0.0016 0.0005 0.0005
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Loa Loa (eye worm) TAR-binding protein 0.0323 0.0797 0.1531
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0054 0.0104 0.0102
Brugia malayi hypothetical protein 0.0374 0.0927 0.1782
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Brugia malayi glutaminase DH11.1 0.1066 0.2709 0.5212
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Brugia malayi nuclear hormone receptor 0.0054 0.0104 0.0196
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0098 0.0217 0.4386
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Toxoplasma gondii type I fatty acid synthase, putative 0.0026 0.0031 0.0963
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Entamoeba histolytica Ras guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0003
Brugia malayi MH2 domain containing protein 0.0062 0.0124 0.0235
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0024 0.0026 0.0021
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0036 0.0058 0.0503
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0054 0.0104 0.0099
Echinococcus granulosus chromobox protein 1 0.0068 0.0139 0.0134
Schistosoma mansoni hypothetical protein 0.0548 0.1374 0.1373
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.0104 0.0196
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0054 0.0104 0.0196
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0478 0.1722
Brugia malayi hypothetical protein 0.0029 0.0038 0.007
Schistosoma mansoni DNA polymerase eta 0.0042 0.0072 0.007
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0054 0.0104 0.0196
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0045
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0024 0.0026 0.0021
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0029 0.0038 0.0036
Plasmodium falciparum importin beta, putative 0.012 0.0272 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0157 0.0369 0.0364
Echinococcus multilocularis ras GTP exchange factor 0.0019 0.0014 0.0009
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0088 0.0191 0.0364
Trypanosoma cruzi DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0024 0.0026 0.0023
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0054 0.0104 0.0099
Trypanosoma brucei hypothetical protein, conserved 0.0072 0.015 0.2932
Schistosoma mansoni tar DNA-binding protein 0.0323 0.0797 0.0795
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Brugia malayi latrophilin 2 splice variant baaae 0.1183 0.3011 0.5793
Schistosoma mansoni regulator of G protein signaling 0.0027 0.0034 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0054 0.0104 0.0196
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0024 0.0027 0.0078
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0451
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0045
Brugia malayi hypothetical protein 0.0026 0.003 0.0055
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.1074 0.2729 0.5251
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Echinococcus granulosus thyroid hormone receptor alpha 0.0026 0.003 0.0025
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0024 0.0026 0.0021
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0014 0.0023
Echinococcus multilocularis tar DNA binding protein 0.0323 0.0797 0.0792
Leishmania major hypothetical protein, conserved 0.0072 0.015 0.2932
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0024 0.0026 0.0021
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0024 0.0026 0.0251
Echinococcus multilocularis mothers against decapentaplegic 6 0.0062 0.0124 0.0119
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0767
Plasmodium falciparum transportin 0.0023 0.0023 0.0346
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Giardia lamblia Kinase, PLK 0.0199 0.0478 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0072 0.015 0.0148
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0029 0.0038 0.007
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0054 0.0104 0.0196
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0026 0.0031 0.0268
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0014 0.0009
Mycobacterium ulcerans Type I modular polyketide synthase 0.0024 0.0027 0.0078
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus granulosus segment polarity protein dishevelled 0.0027 0.0034 0.0029
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.002 0.0016 0.0135
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0323 0.0797 0.0795
Schistosoma mansoni inositol transporter 0.0076 0.0161 0.0159
Onchocerca volvulus 0.0054 0.0104 0.074
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0024 0.0026 0.0451
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0031 0.0043 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0062 0.0438
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0199 0.0478 0.0473
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0068 0.014 0.271
Entamoeba histolytica serine/threonine protein kinase, putative 0.0199 0.0478 0.5079
Schistosoma mansoni ran 0.0088 0.0191 0.0189
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0017
Schistosoma mansoni thyroid hormone receptor 0.0054 0.0104 0.0102
Onchocerca volvulus Serine\/threonine kinase homolog 0.0199 0.0478 0.3458
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0048 0.0088 0.1603
Trichomonas vaginalis guanine nucleotide exchange factor, putative 0.0019 0.0014 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Loa Loa (eye worm) hypothetical protein 0.0026 0.003 0.0054
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0157 0.0369 0.0364
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0054 0.0104 0.0099
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0019 0.0014 0.0009
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0046 0.0083 0.0155
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0024 0.0026 0.0021
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0251
Trypanosoma cruzi guanine nucleotide releasing protein, putative 0.0019 0.0014 0.0007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Brugia malayi GH02984p 0.0693 0.1748 0.3361
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Brugia malayi Sodium:solute symporter family protein 0.0076 0.0161 0.0307
Brugia malayi nuclear hormone receptor 0.0026 0.003 0.0054
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0083 0.0177 0.6447
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0024 0.0026 0.0021
Mycobacterium tuberculosis Possible penicillin-binding protein 0.046 0.1149 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.015 0.0505
Toxoplasma gondii small ubiquitin family modifier, putative 0.006 0.012 0.4293
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0478 0.0476
Loa Loa (eye worm) hypothetical protein 0.012 0.0272 0.0521
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0045
Echinococcus granulosus histone acetyltransferase KAT2B 0.0273 0.0668 0.0664
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0024 0.0026 0.0021
Onchocerca volvulus 0.0024 0.0026 0.0171
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0048 0.0088 0.0083
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1731 0.4421 0.8507
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0018 0.0011 0.0017
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0024 0.0026 0.0451
Brugia malayi hypothetical protein 0.0106 0.0238 0.0455
Trypanosoma brucei importin beta-1 subunit, putative 0.012 0.0272 0.5574
Echinococcus multilocularis dna polymerase kappa 0.0042 0.0072 0.0067
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0181 0.0431 0.0429
Echinococcus granulosus histone acetyltransferase KAT2B 0.0083 0.0177 0.0173
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0042 0.0072 0.0626
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0478 0.1722
Echinococcus multilocularis FTZ F1 alpha 0.0054 0.0104 0.0099
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0048 0.0087 0.0082
Giardia lamblia DINP protein human, muc B family 0.0042 0.0072 0.1251
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Brugia malayi N-terminal motif family protein 0.0549 0.1378 0.265
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0024 0.0026 0.0023
Mycobacterium tuberculosis Conserved protein 0.0072 0.015 0.1305
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0026 0.003 0.0025
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0024 0.0026 0.0128
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0147 0.0279
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0451
Trypanosoma cruzi importin beta-1 subunit, putative 0.0097 0.0214 0.4319
Brugia malayi beta-lactamase 0.0072 0.015 0.0285
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0157 0.0369 0.3885
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0062 0.0124 0.0885
Loa Loa (eye worm) hypothetical protein 0.0072 0.015 0.0285
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Echinococcus granulosus sodium:glucose cotransporter 0.0076 0.0161 0.0156
Trichomonas vaginalis penicillin-binding protein, putative 0.0072 0.015 0.0505
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0054 0.0104 0.0196
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0024 0.0026 0.0451
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0157 0.0369 0.0364
Echinococcus multilocularis expressed protein 0.0101 0.0223 0.0219
Loa Loa (eye worm) hypothetical protein 0.0018 0.0011 0.0017
Schistosoma mansoni nuclear receptor nhr-48 0.0026 0.003 0.0028
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0157 0.0369 0.0706
Loa Loa (eye worm) hypothetical protein 0.0016 0.0005 0.0005
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0054 0.0104 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0034 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Brugia malayi serine/threonine-protein kinase plk-2 0.0199 0.0478 0.0916
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Trypanosoma cruzi polo-like protein kinase, putative 0.0199 0.0478 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0072 0.015 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0024 0.0026 0.0043
Giardia lamblia Hypothetical protein 0.0024 0.0026 0.0251
Schistosoma mansoni importin-beta 2 0.0023 0.0023 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0054 0.0104 0.0196
Loa Loa (eye worm) hypothetical protein 0.0024 0.0026 0.0045
Brugia malayi hypothetical protein 0.0027 0.0034 0.0062
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0199 0.0478 0.0916
Loa Loa (eye worm) hypothetical protein 0.0054 0.0104 0.0196
Loa Loa (eye worm) nuclear hormone receptor 0.0026 0.003 0.0054
Loa Loa (eye worm) transcription factor SMAD2 0.2032 0.5196 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0121 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0026 0.0043
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0024 0.0026 0.0023
Echinococcus multilocularis dna polymerase eta 0.0042 0.0072 0.0067
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0794 0.2009 0.2005
Loa Loa (eye worm) hypothetical protein 0.0038 0.0062 0.0116
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0024 0.0026 0.0251
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0024 0.0026 0.0021
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0024 0.0026 0.0023
Onchocerca volvulus 0.0024 0.0026 0.0171
Onchocerca volvulus 0.0026 0.003 0.0206
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0024 0.0026 0.0023
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0024 0.0026 0.0023
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0024 0.0026 0.0045
Plasmodium falciparum ubiquitin specific protease, putative 0.0024 0.0026 0.0451
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.0072 0.1251
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0023 0.0025 0.0218
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0024 0.0026 0.0767

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.631 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) 3.5481 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of GCN5L2. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504398] ChEMBL. No reference
Potency (functional) = 56.2341 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of DNA Polymerase Beta. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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