Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1471 | 0.2285 |
Echinococcus multilocularis | Carboxy terminal domain RNA polymerase II | 0.0013 | 0.0257 | 0.034 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1343 | 0.1743 |
Loa Loa (eye worm) | hypothetical protein | 0.0192 | 0.7641 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0039 | 0.1343 | 0.2043 |
Brugia malayi | polk-prov protein | 0.0019 | 0.0517 | 0.066 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0039 | 0.1339 | 0.1855 |
Plasmodium vivax | hypothetical protein, conserved | 0.0039 | 0.1343 | 0.3937 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Trypanosoma brucei | unspecified product | 0.0061 | 0.2252 | 0.3753 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.1343 | 0.0863 |
Onchocerca volvulus | 0.0165 | 0.6546 | 0.8564 | |
Echinococcus multilocularis | dna polymerase eta | 0.0142 | 0.5572 | 0.7782 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0125 | 0.0156 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0052 | 0.1886 | 0.2621 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0013 | 0.0257 | 0.0437 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0142 | 0.5572 | 1 |
Echinococcus granulosus | CTD small phosphatase protein like | 0.0013 | 0.0257 | 0.034 |
Trichomonas vaginalis | dullard protein, putative | 0.0013 | 0.0257 | 0.1086 |
Echinococcus multilocularis | 0.0013 | 0.0257 | 0.034 | |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.0866 | 0.1996 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0039 | 0.1343 | 0.0863 |
Mycobacterium leprae | Probable lipase LipE | 0.0039 | 0.1343 | 0.2218 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.025 | 0.031 |
Trichomonas vaginalis | dullard protein, putative | 0.0013 | 0.0257 | 0.1086 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.1343 | 0.2391 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0013 | 0.0257 | 0.1086 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.01 | 0.3837 | 0.6879 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0014 | 0.0019 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0019 | 0.0517 | 0.0906 |
Brugia malayi | N-terminal motif family protein | 0.0192 | 0.7641 | 1 |
Mycobacterium ulcerans | beta-lactamase | 0.0039 | 0.1343 | 0.3305 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1471 | 0.2285 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1343 | 0.1743 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0039 | 0.1343 | 0.1861 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0125 | 0.0156 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0061 | 0.2252 | 0.3753 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0525 | 0.067 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.0743 | 0.1021 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0525 | 0.1777 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0013 | 0.0257 | 0.1086 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0061 | 0.2252 | 0.1822 |
Echinococcus granulosus | dna polymerase eta | 0.0142 | 0.5572 | 0.7782 |
Brugia malayi | hypothetical protein | 0.0165 | 0.6546 | 0.8564 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0009 | 0.0125 | 0.0146 |
Toxoplasma gondii | Dullard family phosphatase domain-containing protein | 0.0013 | 0.0257 | 0.0354 |
Giardia lamblia | Nuclear LIM interactor-interacting factor 1 | 0.0013 | 0.0257 | 0.0499 |
Brugia malayi | beta-lactamase | 0.0039 | 0.1343 | 0.1743 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.0531 | 0.0742 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0019 | 0.0517 | 0.0906 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1343 | 0.1743 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.2504 | 0.4481 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0152 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0152 | 0.0181 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.1343 | 0.5939 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0517 | 0.049 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0274 | 0.0469 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.7156 | 1 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0019 | 0.0517 | 0.0944 |
Brugia malayi | Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 | 0.0013 | 0.0257 | 0.0319 |
Echinococcus multilocularis | Pleckstrin G protein, interacting region | 0.0009 | 0.0125 | 0.0156 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0039 | 0.1343 | 0.1743 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.3016 | 0.3936 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0525 | 0.1077 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0009 | 0.0125 | 0.0156 |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.0743 | 0.1021 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0525 | 0.2053 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0125 | 0.0146 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0052 | 0.1886 | 0.1436 |
Echinococcus granulosus | Carboxy terminal domain RNA polymerase II | 0.0013 | 0.0257 | 0.034 |
Schistosoma mansoni | nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) | 0.0013 | 0.0257 | 0.0359 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0042 | 0.1471 | 0.2285 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0013 | 0.0274 | 0.1164 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0013 | 0.0257 | 0.1086 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0019 | 0.0517 | 0.049 |
Schistosoma mansoni | dep domain containing protein | 0.0009 | 0.0125 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0517 | 0.066 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0067 | 0.2504 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.1343 | 0.1876 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0039 | 0.1343 | 0.3305 |
Loa Loa (eye worm) | beta-lactamase | 0.0039 | 0.1343 | 0.1743 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.1343 | 0.5939 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0525 | 0.092 |
Brugia malayi | Domain found in Dishevelled, Egl-10, and Pleckstrin family protein | 0.0009 | 0.0125 | 0.0146 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0027 | 0.0866 | 0.2209 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0525 | 0.0733 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0039 | 0.1343 | 0.1743 |
Echinococcus multilocularis | dna polymerase kappa | 0.0061 | 0.2252 | 0.3134 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.4803 | 0.628 |
Mycobacterium ulcerans | lipase LipD | 0.0039 | 0.1343 | 0.3305 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0125 | 0.0146 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0009 | 0.0125 | 0.0146 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0061 | 0.2252 | 0.2934 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0039 | 0.1343 | 0.0863 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.2504 | 0.4481 |
Onchocerca volvulus | 0.0039 | 0.1343 | 0.1743 | |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.4027 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0525 | 0.067 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0039 | 0.1343 | 0.5939 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 0.5 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0019 | 0.0517 | 0.049 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0525 | 0.092 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0621 | 0.1637 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.0152 | 0.0212 |
Schistosoma mansoni | hypothetical protein | 0.018 | 0.7156 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0061 | 0.2252 | 0.6943 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0019 | 0.0517 | 0.0906 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0274 | 0.0033 |
Leishmania major | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0525 | 0.0032 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0061 | 0.2252 | 0.2934 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0866 | 0.2494 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.1343 | 0.0863 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0142 | 0.5572 | 0.7287 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.0743 | 0.0956 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0525 | 0.2285 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0061 | 0.2252 | 1 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 0.4203 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0039 | 0.1343 | 0.0863 |
Onchocerca volvulus | 0.0039 | 0.1343 | 0.1743 | |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0067 | 0.2504 | 0.4229 |
Giardia lamblia | DINP protein human, muc B family | 0.0061 | 0.2252 | 1 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0067 | 0.2504 | 0.3487 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1343 | 0.1743 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0009 | 0.0125 | 0.0146 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0009 | 0.0125 | 0.0156 |
Mycobacterium leprae | conserved hypothetical protein | 0.0039 | 0.1343 | 0.2218 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0409 | 0.0764 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.1343 | 0.1743 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.001 | 0.0152 | 0.0193 |
Schistosoma mansoni | ras GTP exchange factor | 0.0007 | 0.0014 | 0.0019 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0192 | 0.7641 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.1343 | 0.5939 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0152 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0125 | 0.0146 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.01 | 0.3837 | 1 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0125 | 0.0156 |
Toxoplasma gondii | ABC1 family protein | 0.0039 | 0.1343 | 0.328 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0017 | 0.0417 | 0.0581 |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0.1343 | 0.2043 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0274 | 0.0033 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0019 | 0.0517 | 0.1055 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0052 | 0.1886 | 0.1436 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.001 | 0.0152 | 0.0193 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0019 | 0.0517 | 0.0906 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.3016 | 0.7787 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.008 | 0.3016 | 0.7787 |
Plasmodium falciparum | NLI interacting factor-like phosphatase, putative | 0.0013 | 0.0257 | 0.0366 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0039 | 0.1343 | 0.1861 |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.0743 | 0.0956 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0067 | 0.2504 | 0.3266 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0525 | 0.0716 |
Trichomonas vaginalis | dullard protein, putative | 0.0013 | 0.0257 | 0.1086 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0061 | 0.2252 | 0.3753 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.0517 | 0.049 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.001 | 0.0152 | 0.0193 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0152 | 0.0071 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0019 | 0.0517 | 0.1055 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0525 | 0.0505 |
Onchocerca volvulus | 0.0039 | 0.1343 | 0.1743 | |
Leishmania major | DNA polymerase eta, putative | 0.01 | 0.3837 | 0.6736 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0052 | 0.1886 | 0.2621 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0039 | 0.1343 | 0.1876 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0125 | 0.0175 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0525 | 0.0716 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0061 | 0.2252 | 0.3134 |
Schistosoma mansoni | guanine-nucleotide-exchange-factor | 0.0007 | 0.0014 | 0.0019 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0061 | 0.2252 | 0.1822 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0019 | 0.0517 | 0.0722 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.4027 |
Schistosoma mansoni | DNA polymerase eta | 0.0142 | 0.5572 | 0.7786 |
Leishmania major | DNA damage repair protein, putative | 0.0019 | 0.0517 | 0.049 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0039 | 0.1343 | 0.0863 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0014 | 0.0019 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0009 | 0.0125 | 0.0146 |
Echinococcus granulosus | dna polymerase kappa | 0.0061 | 0.2252 | 0.3134 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0067 | 0.2504 | 0.3487 |
Brugia malayi | Probable ClpP-like protease | 0.008 | 0.3016 | 0.3936 |
Mycobacterium ulcerans | hypothetical protein | 0.0039 | 0.1343 | 0.3305 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.4027 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0039 | 0.1343 | 0.5939 |
Schistosoma mansoni | hypothetical protein | 0.0012 | 0.025 | 0.035 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0039 | 0.1343 | 0.0863 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0142 | 0.5572 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0152 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0125 | 0.0146 |
Schistosoma mansoni | regulator of G protein signaling | 0.0009 | 0.0125 | 0.0175 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.0152 | 0.0212 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0019 | 0.0517 | 0.049 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.008 | 0.3016 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.1343 | 0.2391 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0061 | 0.2252 | 0.3753 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0525 | 0.1303 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0525 | 0.2285 |
Brugia malayi | DIX domain containing protein | 0.0009 | 0.0125 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0125 | 0.0146 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0125 | 0.0156 |
Brugia malayi | hypothetical protein | 0.0009 | 0.0125 | 0.0146 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0039 | 0.1343 | 0.0863 |
Trichomonas vaginalis | nuclear lim interactor-interacting factor, putative | 0.0013 | 0.0257 | 0.1086 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0009 | 0.0125 | 0.0175 |
Echinococcus granulosus | geminin | 0.018 | 0.7156 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0257 | 0.0319 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0067 | 0.2504 | 0.3266 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0039 | 0.1343 | 0.5939 |
Trypanosoma brucei | unspecified product | 0.0042 | 0.1471 | 0.2285 |
Brugia malayi | beta-lactamase family protein | 0.0039 | 0.1343 | 0.1743 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0067 | 0.2504 | 0.35 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.5572 | 0.7287 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 0.4203 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0019 | 0.0517 | 0.1275 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0061 | 0.2252 | 0.3147 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.0019 | 0.0517 | 0.049 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Echinococcus granulosus | Pleckstrin G protein interacting region | 0.0009 | 0.0125 | 0.0156 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0152 | 0.0071 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0039 | 0.1343 | 0.3305 |
Echinococcus multilocularis | geminin | 0.018 | 0.7156 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0052 | 0.1886 | 0.4744 |
Onchocerca volvulus | 0.0009 | 0.0125 | 0.0146 | |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.008 | 0.3016 | 1 |
Entamoeba histolytica | NLI interacting factor-like phosphatase domain-containing protein | 0.0013 | 0.0257 | 0.0976 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0061 | 0.2252 | 0.6943 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0525 | 0.0733 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.008 | 0.3016 | 0.4214 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 1 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0061 | 0.2252 | 0.3147 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0525 | 0.0505 |
Giardia lamblia | DNA damage repair protein | 0.0019 | 0.0517 | 0.1739 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.6546 | 0.8564 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.0743 | 0.3259 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0061 | 0.2252 | 0.3134 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0067 | 0.2504 | 0.4229 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0009 | 0.0125 | 0.0156 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.001 | 0.0152 | 0.0193 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.4027 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1343 | 0.1743 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.0517 | 0.049 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0525 | 0.0973 |
Mycobacterium tuberculosis | Conserved protein | 0.0039 | 0.1343 | 0.0863 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0061 | 0.2252 | 0.3753 |
Schistosoma mansoni | fyve finger-containing phosphoinositide kinase fyv1 | 0.0009 | 0.0125 | 0.0175 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0039 | 0.1339 | 0.1855 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0019 | 0.0517 | 0.049 |
Trypanosoma brucei | unspecified product | 0.0042 | 0.1471 | 0.2285 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.008 | 0.3016 | 1 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0061 | 0.2252 | 0.8985 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0743 | 0.3259 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0009 | 0.0125 | 0.0156 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0061 | 0.2252 | 0.3753 |
Schistosoma mansoni | nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) | 0.0013 | 0.0257 | 0.0359 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0039 | 0.1343 | 0.0863 |
Leishmania major | DNA polymerase eta, putative | 0.0142 | 0.5572 | 1 |
Entamoeba histolytica | recQ family helicase, putative | 0.0013 | 0.0274 | 0.1046 |
Schistosoma mansoni | ras GTP exchange factor son of sevenless | 0.0007 | 0.0014 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.1343 | 0.1743 |
Schistosoma mansoni | dishevelled | 0.0009 | 0.0125 | 0.0175 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0061 | 0.2252 | 1 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0866 | 0.137 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 39.8107 uM | PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 100 uM | PUBCHEM_BIOASSAY: Inhibitors of TCP-1 ring complex (TRiC) of Methanococcus maripaludis (MmCpn): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488991] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.