Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | nuclear factor, erythroid 2-like 2 | Starlite/ChEMBL | No references |
Human immunodeficiency virus 1 | Aberrant vpr protein | Starlite/ChEMBL | No references |
Homo sapiens | potassium voltage-gated channel, subfamily H (eag-related), member 2 | Starlite/ChEMBL | No references |
Homo sapiens | thyroid stimulating hormone receptor | Starlite/ChEMBL | No references |
Homo sapiens | synuclein, alpha (non A4 component of amyloid precursor) | Starlite/ChEMBL | No references |
Homo sapiens | cytochrome P450, family 3, subfamily A, polypeptide 4 | Starlite/ChEMBL | No references |
Homo sapiens | SMAD family member 2 | Starlite/ChEMBL | No references |
Homo sapiens | runt-related transcription factor 1 | Starlite/ChEMBL | No references |
Homo sapiens | isocitrate dehydrogenase 1 (NADP+), soluble | Starlite/ChEMBL | No references |
Homo sapiens | nuclear receptor subfamily 1, group H, member 4 | Starlite/ChEMBL | No references |
Homo sapiens | tumor protein p53 | Starlite/ChEMBL | No references |
Homo sapiens | androgen receptor | Starlite/ChEMBL | No references |
Homo sapiens | estrogen receptor 1 | Starlite/ChEMBL | No references |
Homo sapiens | retinoid X receptor, alpha | Starlite/ChEMBL | No references |
Homo sapiens | RAR-related orphan receptor C | Starlite/ChEMBL | No references |
Homo sapiens | geminin, DNA replication inhibitor | Starlite/ChEMBL | No references |
Homo sapiens | vitamin D (1,25- dihydroxyvitamin D3) receptor | Starlite/ChEMBL | No references |
Rattus norvegicus | Inositol monophosphatase 1 | Starlite/ChEMBL | No references |
Rattus norvegicus | Thioredoxin reductase 1, cytoplasmic | Starlite/ChEMBL | No references |
Homo sapiens | polymerase (DNA directed) kappa | Starlite/ChEMBL | No references |
Homo sapiens | lysine (K)-specific demethylase 4A | Starlite/ChEMBL | No references |
Homo sapiens | hydroxysteroid (17-beta) dehydrogenase 10 | Starlite/ChEMBL | No references |
Bacillus anthracis | Anthrax lethal factor | Starlite/ChEMBL | No references |
Homo sapiens | arachidonate 15-lipoxygenase | Starlite/ChEMBL | No references |
Homo sapiens | glucagon-like peptide 1 receptor | Starlite/ChEMBL | No references |
Homo sapiens | peroxisome proliferator-activated receptor gamma | Starlite/ChEMBL | No references |
Homo sapiens | heat shock protein 90kDa alpha (cytosolic), class A member 1 | Starlite/ChEMBL | No references |
Homo sapiens | EYA transcriptional coactivator and phosphatase 2 | Starlite/ChEMBL | No references |
Homo sapiens | aldehyde dehydrogenase 1 family, member A1 | Starlite/ChEMBL | No references |
Plasmodium falciparum | heat shock protein 90, putative | Starlite/ChEMBL | No references |
Homo sapiens | core-binding factor, beta subunit | No references | |
Homo sapiens | peroxisome proliferator-activated receptor delta | Starlite/ChEMBL | No references |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Smad1 | 0.0033 | 0.0146 | 0.0146 |
Echinococcus granulosus | FTZ F1 alpha | 0.0084 | 0.0695 | 0.1644 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0115 | 0.104 | 0.246 |
Plasmodium falciparum | thioredoxin reductase | 0.0057 | 0.0406 | 0.1965 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0069 | 0.0539 | 0.9244 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0073 | 0.0576 | 0.0535 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0037 | 0.0185 | 0.0437 |
Schistosoma mansoni | smad | 0.0033 | 0.0146 | 0.0726 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.005 | 0.0325 | 0.8384 |
Trypanosoma brucei | trypanothione reductase | 0.0057 | 0.0406 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0387 | 0.9526 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0695 | 0.0654 |
Plasmodium falciparum | endoplasmin, putative | 0.004 | 0.0222 | 0.1073 |
Brugia malayi | MH2 domain containing protein | 0.0033 | 0.0146 | 0.0146 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0084 | 0.0695 | 0.0695 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0045 | 0.027 | 0.6981 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0039 | 0.0214 | 0.0506 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0044 | 0.0265 | 0.1319 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0045 | 0.027 | 0.4635 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0943 | 0.0904 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0035 | 0.0168 | 0.0125 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0045 | 0.027 | 0.1307 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0024 | 0.0044 | 0.0212 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0024 | 0.0044 | 0.0104 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0039 | 0.0214 | 0.0506 |
Brugia malayi | nuclear hormone receptor | 0.0084 | 0.0695 | 0.0695 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0055 | 0.0387 | 0.0345 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0045 | 0.027 | 0.0638 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Leishmania major | trypanothione reductase | 0.0057 | 0.0406 | 0.697 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0084 | 0.0695 | 0.1644 |
Plasmodium vivax | glutathione reductase, putative | 0.0057 | 0.0406 | 0.1965 |
Loa Loa (eye worm) | runx1 | 0.0067 | 0.0515 | 0.0473 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0033 | 0.0146 | 0.0345 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.013 | 0.1203 | 0.8837 |
Brugia malayi | ecdysone receptor | 0.0039 | 0.0214 | 0.0214 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0055 | 0.0387 | 1 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0025 | 0.0062 | 0.0453 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0057 | 0.0406 | 0.0961 |
Brugia malayi | MH2 domain containing protein | 0.0033 | 0.0146 | 0.0146 |
Echinococcus granulosus | dna polymerase kappa | 0.005 | 0.0325 | 0.0768 |
Schistosoma mansoni | heat shock protein | 0.0055 | 0.0387 | 0.1923 |
Brugia malayi | steroid hormone receptor | 0.0084 | 0.0695 | 0.0695 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0044 | 0.0044 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0203 | 0.1991 | 0.9893 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0084 | 0.0695 | 0.1644 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0387 | 0.9526 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0084 | 0.0695 | 0.3452 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.004 | 0.0219 | 0.1611 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0084 | 0.0695 | 0.1644 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0047 | 0.03 | 0.071 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0052 | 0.035 | 0.1145 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0043 | 0.0249 | 0.0206 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0084 | 0.0695 | 0.1644 |
Mycobacterium ulcerans | DNA polymerase IV | 0.005 | 0.0325 | 0.5567 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0045 | 0.027 | 0.0639 |
Onchocerca volvulus | 0.0039 | 0.0214 | 0.0171 | |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0387 | 0.9526 |
Echinococcus multilocularis | heat shock protein 90 | 0.0055 | 0.0387 | 0.0916 |
Brugia malayi | nuclear hormone receptor | 0.0039 | 0.0214 | 0.0214 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0039 | 0.0214 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Schistosoma mansoni | rab6-interacting | 0.0024 | 0.0044 | 0.0218 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Brugia malayi | MH2 domain containing protein | 0.0487 | 0.5091 | 0.5091 |
Schistosoma mansoni | smad1 5 8 and | 0.0033 | 0.0146 | 0.0726 |
Loa Loa (eye worm) | hypothetical protein | 0.0535 | 0.561 | 0.559 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Onchocerca volvulus | 0.0084 | 0.0695 | 0.0654 | |
Brugia malayi | conserved hypotetical protein | 0.0039 | 0.0214 | 0.0214 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0069 | 0.0539 | 0.2677 |
Brugia malayi | nuclear receptor RXR | 0.0039 | 0.0214 | 0.0214 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0.027 | 0.6651 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0045 | 0.027 | 0.6981 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0003 | 0.0063 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0084 | 0.0695 | 0.1644 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0033 | 0.0146 | 0.0345 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.0387 | 0.9526 |
Brugia malayi | Doublecortin family protein | 0.0024 | 0.0044 | 0.0044 |
Echinococcus granulosus | Smad4 | 0.0033 | 0.0146 | 0.0345 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0039 | 0.0214 | 0.1063 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0039 | 0.0214 | 0.0171 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Brugia malayi | Endoplasmin precursor | 0.0055 | 0.0387 | 0.0387 |
Schistosoma mansoni | hypothetical protein | 0.0043 | 0.0258 | 0.128 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0052 | 0.035 | 0.6004 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.0387 | 0.9526 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0039 | 0.0214 | 0.0506 |
Schistosoma mansoni | heat shock protein | 0.0055 | 0.0387 | 0.1923 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0035 | 0.0168 | 0.0812 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0069 | 0.0539 | 0.3959 |
Loa Loa (eye worm) | inositol-1 | 0.0045 | 0.027 | 0.0227 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0069 | 0.0539 | 0.9244 |
Echinococcus granulosus | heat shock protein 90 | 0.0047 | 0.03 | 0.071 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0073 | 0.0583 | 0.2819 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0084 | 0.0695 | 0.0695 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0057 | 0.0406 | 0.1965 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0.027 | 0.6651 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0442 | 0.04 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0045 | 0.027 | 0.027 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0145 | 0.1361 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0084 | 0.0695 | 0.1644 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0084 | 0.0695 | 0.0654 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0043 | 0.0249 | 0.0588 |
Leishmania major | DNA polymerase kappa, putative | 0.0025 | 0.0062 | 0.1057 |
Schistosoma mansoni | smad1 5 8 and | 0.0033 | 0.0146 | 0.0726 |
Schistosoma mansoni | lozenge | 0.0067 | 0.0515 | 0.2559 |
Trichomonas vaginalis | endoplasmin, putative | 0.004 | 0.0222 | 0.5731 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.013 | 0.1203 | 0.8837 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0045 | 0.027 | 0.4223 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0265 | 0.0223 |
Schistosoma mansoni | zinc finger protein | 0.0039 | 0.0214 | 0.1063 |
Giardia lamblia | Grp94/Hsp90 | 0.0052 | 0.035 | 0.9044 |
Brugia malayi | ecdysteroid receptor | 0.0084 | 0.0695 | 0.0695 |
Onchocerca volvulus | Alhambra homolog | 0.0035 | 0.0168 | 0.0125 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0084 | 0.0695 | 0.3452 |
Brugia malayi | Hsp90 protein | 0.0037 | 0.0185 | 0.0185 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0695 | 0.0654 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0055 | 0.0387 | 0.9526 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0.027 | 0.6651 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0055 | 0.0387 | 0.9526 |
Plasmodium vivax | heat shock protein 86, putative | 0.0055 | 0.0387 | 0.1872 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0039 | 0.0214 | 0.0171 |
Trichomonas vaginalis | heat shock protein, putative | 0.004 | 0.0222 | 0.5731 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0039 | 0.0214 | 0.0214 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.0249 | 0.1235 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0145 | 0.1361 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0039 | 0.0214 | 0.0171 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0258 | 0.36 |
Brugia malayi | glutathione reductase | 0.0057 | 0.0406 | 0.0406 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0039 | 0.0214 | 0.0171 |
Trichomonas vaginalis | heat shock protein, putative | 0.0052 | 0.035 | 0.9044 |
Schistosoma mansoni | nuclear receptor | 0.0039 | 0.0214 | 0.1063 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0057 | 0.0406 | 0.2985 |
Brugia malayi | jmjC domain containing protein | 0.0115 | 0.104 | 0.104 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0084 | 0.0695 | 0.0695 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0193 | 0.4757 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0047 | 0.03 | 0.7751 |
Echinococcus multilocularis | heat shock protein | 0.0055 | 0.0387 | 0.0916 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0084 | 0.0695 | 0.0654 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0037 | 0.0185 | 0.0142 |
Plasmodium vivax | endoplasmin, putative | 0.0055 | 0.0387 | 0.1872 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0695 | 0.0654 |
Schistosoma mansoni | lipoxygenase | 0.0067 | 0.0511 | 0.2536 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0065 | 0.0488 | 0.0446 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0073 | 0.0583 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0039 | 0.0214 | 0.0214 |
Plasmodium falciparum | heat shock protein 90 | 0.0055 | 0.0387 | 0.1872 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0265 | 0.0223 |
Schistosoma mansoni | rab6-interacting | 0.0024 | 0.0044 | 0.0218 |
Echinococcus multilocularis | geminin | 0.0205 | 0.2013 | 0.4761 |
Schistosoma mansoni | heat shock protein | 0.0037 | 0.0185 | 0.0918 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0145 | 0.1361 | 1 |
Echinococcus multilocularis | Smad4 | 0.0033 | 0.0146 | 0.0345 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0084 | 0.0695 | 0.1644 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0055 | 0.0387 | 0.9526 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0084 | 0.0695 | 0.0695 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0038 | 0.0193 | 0.4757 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0084 | 0.0695 | 0.0654 |
Schistosoma mansoni | nuclear hormone receptor | 0.0039 | 0.0214 | 0.1063 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0084 | 0.0695 | 0.0695 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0258 | 0.36 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0043 | 0.0258 | 0.0609 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0084 | 0.0695 | 0.0654 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0049 | 0.0314 | 0.1561 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0052 | 0.035 | 0.6004 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0043 | 0.0258 | 0.0609 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0695 | 0.0654 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0073 | 0.0583 | 0.2896 |
Brugia malayi | jmjC domain containing protein | 0.0043 | 0.0249 | 0.0249 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.013 | 0.1203 | 0.8837 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0024 | 0.0044 | 0.0104 |
Schistosoma mansoni | smad1 5 8 and | 0.0033 | 0.0146 | 0.0726 |
Brugia malayi | nuclear receptor NHR-88 | 0.0039 | 0.0214 | 0.0214 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0387 | 0.9526 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0073 | 0.0583 | 1 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0052 | 0.035 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.0035 | 0.0168 | 0.0812 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Echinococcus granulosus | heat shock protein 90 | 0.0055 | 0.0387 | 0.0916 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Brugia malayi | hypothetical protein | 0.0044 | 0.0265 | 0.0265 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0033 | 0.0146 | 0.0103 |
Trichomonas vaginalis | heat shock protein, putative | 0.0052 | 0.035 | 0.9044 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0084 | 0.0695 | 0.1644 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0073 | 0.0583 | 0.4283 |
Mycobacterium ulcerans | DNA polymerase IV | 0.005 | 0.0325 | 0.5567 |
Onchocerca volvulus | 0.0039 | 0.0214 | 0.0171 | |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0035 | 0.0168 | 0.0397 |
Schistosoma mansoni | endoplasmin | 0.0055 | 0.0387 | 0.1923 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0037 | 0.0185 | 0.0894 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0435 | 0.0393 |
Echinococcus granulosus | endoplasmin | 0.0052 | 0.035 | 0.0828 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0084 | 0.0695 | 0.0654 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0057 | 0.0406 | 0.0961 |
Brugia malayi | hypothetical protein | 0.0106 | 0.0943 | 0.0943 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0084 | 0.0695 | 0.0695 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0067 | 0.0511 | 0.1207 |
Loa Loa (eye worm) | hypothetical protein | 0.0535 | 0.561 | 0.559 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0024 | 0.0044 | 0.0104 |
Echinococcus multilocularis | RUN | 0.0024 | 0.0044 | 0.0104 |
Echinococcus multilocularis | Protein lozenge | 0.0067 | 0.0515 | 0.1219 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Schistosoma mansoni | nuclear hormone receptor | 0.0084 | 0.0695 | 0.3452 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0033 | 0.0146 | 0.0726 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0387 | 0.9526 |
Schistosoma mansoni | thyroid hormone receptor | 0.0084 | 0.0695 | 0.3452 |
Trypanosoma cruzi | heat shock protein, putative | 0.0037 | 0.0185 | 0.4549 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0084 | 0.0695 | 0.0695 |
Echinococcus multilocularis | dna polymerase kappa | 0.005 | 0.0325 | 0.0768 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0695 | 0.0654 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0003 | 0.0063 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0084 | 0.0695 | 0.1644 |
Mycobacterium tuberculosis | Probable reductase | 0.013 | 0.1203 | 0.8837 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0168 | 0.0812 |
Brugia malayi | hypothetical protein | 0.0535 | 0.561 | 0.561 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.028 | 0.283 | 0.2799 |
Brugia malayi | hypothetical protein | 0.0044 | 0.0265 | 0.0265 |
Plasmodium falciparum | heat shock protein 90, putative | 0.021 | 0.2068 | 1 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0037 | 0.0185 | 0.0142 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0024 | 0.0044 | 0.0104 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.021 | 0.2068 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0258 | 0.36 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.2013 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0024 | 0.0044 | 0.0104 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0069 | 0.0539 | 0.9244 |
Schistosoma mansoni | coup transcription factor | 0.0084 | 0.0695 | 0.3452 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.005 | 0.0325 | 0.8384 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0039 | 0.0214 | 0.0506 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0033 | 0.0146 | 0.0103 |
Schistosoma mansoni | loxhd1 | 0.0024 | 0.0044 | 0.0218 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0084 | 0.0695 | 0.3452 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0084 | 0.0695 | 0.0695 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0039 | 0.0214 | 0.0506 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0073 | 0.0583 | 0.2896 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0037 | 0.0185 | 0.4549 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0039 | 0.0214 | 0.0214 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0487 | 0.5091 | 0.507 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0233 | 0.1156 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0265 | 0.0223 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0055 | 0.0387 | 0.9526 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0042 | 0.0238 | 0.614 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0214 | 0.0214 |
Schistosoma mansoni | nuclear hormone receptor | 0.0039 | 0.0214 | 0.1063 |
Giardia lamblia | DINP protein human, muc B family | 0.0025 | 0.0062 | 0.1592 |
Plasmodium vivax | heat shock protein, putative | 0.021 | 0.2068 | 1 |
Treponema pallidum | heat shock protein 90 | 0.0052 | 0.035 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0049 | 0.0314 | 0.1561 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0387 | 0.9526 |
Brugia malayi | Thioredoxin reductase | 0.0057 | 0.0406 | 0.0406 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0084 | 0.0695 | 0.3452 |
Schistosoma mansoni | lipoxygenase | 0.0024 | 0.0044 | 0.0218 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0084 | 0.0695 | 0.3452 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0039 | 0.0214 | 0.1063 |
Schistosoma mansoni | jumonji domain containing protein | 0.0092 | 0.0782 | 0.3886 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.005 | 0.0325 | 0.7987 |
Entamoeba histolytica | hypothetical protein | 0.0043 | 0.0258 | 0.36 |
Trypanosoma brucei | unspecified product | 0.0042 | 0.0238 | 0.5852 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0084 | 0.0695 | 0.0695 |
Brugia malayi | nuclear receptor RXR | 0.0044 | 0.0265 | 0.0265 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0084 | 0.0695 | 0.3452 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0084 | 0.0695 | 0.1644 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0695 | 0.0654 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0073 | 0.0583 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.013 | 0.1203 | 0.8614 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0043 | 0.0249 | 0.1235 |
Plasmodium falciparum | glutathione reductase | 0.0057 | 0.0406 | 0.1965 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0045 | 0.027 | 0.772 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0055 | 0.0387 | 0.1872 |
Giardia lamblia | PHD finger protein 15 | 0.0035 | 0.0168 | 0.4338 |
Trichomonas vaginalis | heat shock protein, putative | 0.0032 | 0.0135 | 0.3482 |
Brugia malayi | follicle stimulating hormone receptor | 0.028 | 0.283 | 0.283 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0084 | 0.0695 | 0.0695 |
Plasmodium vivax | heat shock protein 90, putative | 0.0037 | 0.0185 | 0.0894 |
Trichomonas vaginalis | heat shock protein, putative | 0.0047 | 0.03 | 0.7751 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0193 | 0.015 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0084 | 0.0695 | 0.0654 |
Echinococcus multilocularis | peregrin | 0.0035 | 0.0168 | 0.0397 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0084 | 0.0695 | 0.1644 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0045 | 0.027 | 0.6981 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0084 | 0.0695 | 0.1644 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0055 | 0.0387 | 0.9526 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0039 | 0.0214 | 0.0214 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0214 | 0.0214 |
Echinococcus granulosus | tumor protein p63 | 0.0408 | 0.4228 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0487 | 0.5091 | 0.507 |
Echinococcus multilocularis | heat shock protein 90 | 0.0047 | 0.03 | 0.071 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0033 | 0.0146 | 0.0345 |
Brugia malayi | PHD-finger family protein | 0.0035 | 0.0168 | 0.0168 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0203 | 0.1991 | 0.471 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0035 | 0.0168 | 0.0812 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0067 | 0.0511 | 0.1207 |
Schistosoma mansoni | endoplasmin | 0.0055 | 0.0387 | 0.1923 |
Loa Loa (eye worm) | DR-78 | 0.0039 | 0.0214 | 0.0171 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0084 | 0.0695 | 0.0695 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.005 | 0.0325 | 0.7987 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0073 | 0.0583 | 0.1379 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0057 | 0.0406 | 1 |
Brugia malayi | Inositol-1 | 0.0045 | 0.027 | 0.027 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0084 | 0.0695 | 0.0654 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0084 | 0.0695 | 0.0695 |
Brugia malayi | heat shock protein 90 | 0.0055 | 0.0387 | 0.0387 |
Schistosoma mansoni | polycystin 1-related | 0.0024 | 0.0044 | 0.0218 |
Echinococcus multilocularis | smad | 0.0033 | 0.0146 | 0.0345 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0035 | 0.0168 | 0.0397 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0003 | 0.0063 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.006 | 0.0435 | 0.2161 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0055 | 0.0387 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0145 | 0.1361 | 1 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0037 | 0.0185 | 0.0437 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.013 | 0.1203 | 0.8837 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0084 | 0.0695 | 0.3452 |
Echinococcus granulosus | peregrin | 0.0035 | 0.0168 | 0.0397 |
Echinococcus multilocularis | endoplasmin | 0.0052 | 0.035 | 0.0828 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0039 | 0.0214 | 0.0214 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0158 | 0.151 | 0.3572 |
Schistosoma mansoni | eyes absent homolog | 0.0106 | 0.0943 | 0.4687 |
Brugia malayi | polk-prov protein | 0.0038 | 0.0193 | 0.0193 |
Schistosoma mansoni | inositol monophosphatase | 0.0045 | 0.027 | 0.1343 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0049 | 0.0318 | 0.0752 |
Brugia malayi | Bromodomain containing protein | 0.0035 | 0.0168 | 0.0168 |
Loa Loa (eye worm) | Smad1 | 0.0033 | 0.0146 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0039 | 0.0214 | 0.0506 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0084 | 0.0695 | 0.0695 |
Schistosoma mansoni | inositol monophosphatase | 0.0045 | 0.027 | 0.1343 |
Leishmania major | heat shock protein, putative | 0.0037 | 0.0185 | 0.317 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0084 | 0.0695 | 0.0654 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0084 | 0.0695 | 0.3452 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0043 | 0.0249 | 0.0588 |
Brugia malayi | nuclear receptor NHR-67 | 0.0039 | 0.0214 | 0.0214 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0168 | 0.0834 |
Echinococcus granulosus | heat shock protein | 0.0055 | 0.0387 | 0.0916 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0233 | 0.019 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0084 | 0.0695 | 0.1644 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0069 | 0.0539 | 0.1275 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0084 | 0.0695 | 0.0695 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Onchocerca volvulus | 0.0535 | 0.561 | 0.559 | |
Toxoplasma gondii | heat shock protein 90, putative | 0.0055 | 0.0387 | 0.1872 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0025 | 0.0062 | 0.1516 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0387 | 0.9526 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0695 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0023 | 0.0037 | 0.0906 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0039 | 0.0214 | 0.0506 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0044 | 0.0265 | 0.0223 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0039 | 0.0214 | 0.1063 |
Brugia malayi | MH1 domain containing protein | 0.0033 | 0.0146 | 0.0146 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0084 | 0.0695 | 0.0695 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0084 | 0.0695 | 0.0695 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0206 | 0.0162 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0033 | 0.0146 | 0.0345 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0069 | 0.0539 | 0.1275 |
Loa Loa (eye worm) | endoplasmin | 0.0055 | 0.0387 | 0.0345 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0035 | 0.0168 | 0.0834 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0042 | 0.0238 | 0.5852 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.013 | 0.1203 | 0.8837 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.006 | 0.044 | 0.044 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0025 | 0.0062 | 0.1057 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0044 | 0.0265 | 0.0628 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0041 | 0.0233 | 0.0233 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0042 | 0.0238 | 0.614 |
Onchocerca volvulus | 0.006 | 0.0435 | 0.0393 | |
Schistosoma mansoni | Smad4 | 0.0033 | 0.0146 | 0.0726 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0024 | 0.0044 | 0.0104 |
Toxoplasma gondii | thioredoxin reductase | 0.0057 | 0.0406 | 0.1965 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0047 | 0.03 | 0.7384 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0039 | 0.0214 | 0.0506 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0073 | 0.0583 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0033 | 0.0146 | 0.0146 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0039 | 0.0214 | 0.0506 |
Brugia malayi | tailless protein | 0.0039 | 0.0214 | 0.0214 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0115 | 0.104 | 0.246 |
Schistosoma mansoni | nuclear receptor | 0.0039 | 0.0214 | 0.1063 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.006 | 0.044 | 0.0398 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.005 | 0.0325 | 0.7987 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0052 | 0.035 | 0.2572 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0044 | 0.0265 | 0.0628 |
Brugia malayi | nuclear receptor NHR-88 | 0.0084 | 0.0695 | 0.0695 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0024 | 0.0044 | 0.0212 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0084 | 0.0695 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Echinococcus granulosus | jumonji domain containing protein | 0.0049 | 0.0318 | 0.0752 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.006 | 0.044 | 0.044 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0214 | 0.0171 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0044 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0695 | 0.0654 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0055 | 0.0387 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0168 | 0.0125 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0044 | 0.0265 | 0.1319 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.044 | 0.0398 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0044 | 0.0265 | 0.0265 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0084 | 0.0695 | 0.1644 |
Trypanosoma brucei | heat shock protein, putative | 0.0055 | 0.0387 | 0.9526 |
Echinococcus multilocularis | tumor protein p63 | 0.0408 | 0.4228 | 1 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0069 | 0.0539 | 0.0539 |
Echinococcus granulosus | RUN | 0.0024 | 0.0044 | 0.0104 |
Leishmania major | heat shock protein 83-1 | 0.0055 | 0.0387 | 0.6639 |
Loa Loa (eye worm) | glutathione reductase | 0.0057 | 0.0406 | 0.0364 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0043 | 0.0258 | 0.128 |
Brugia malayi | hypothetical protein | 0.0024 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0943 | 0.0904 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0044 | 0.0265 | 0.0265 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0055 | 0.0387 | 0.9526 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0265 | 0.0223 |
Echinococcus granulosus | smad | 0.0033 | 0.0146 | 0.0345 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0084 | 0.0695 | 0.1644 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0073 | 0.0583 | 0.1379 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0084 | 0.0695 | 0.1644 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0045 | 0.027 | 0.4635 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0265 | 0.0223 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0084 | 0.0695 | 0.0654 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0084 | 0.0695 | 0.0654 |
Brugia malayi | hypothetical protein | 0.0043 | 0.0258 | 0.0258 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0039 | 0.0214 | 0.0506 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0057 | 0.0406 | 0.0364 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0039 | 0.0214 | 0.0214 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0045 | 0.027 | 0.0638 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0032 | 0.0135 | 0.0652 |
Schistosoma mansoni | thyroid hormone receptor | 0.0084 | 0.0695 | 0.3452 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.2013 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0045 | 0.027 | 0.0227 |
Trichomonas vaginalis | heat shock protein, putative | 0.0055 | 0.0387 | 1 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0045 | 0.027 | 0.0639 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0039 | 0.0214 | 0.0506 |
Echinococcus granulosus | geminin | 0.0205 | 0.2013 | 0.4761 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0047 | 0.03 | 0.7384 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
AC50 (functional) | = 3.26 uM | PUBCHEM_BIOASSAY: Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504596] | ChEMBL. | No reference |
AC50 (functional) | = 4.525 uM | PUBCHEM_BIOASSAY: HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504596] | ChEMBL. | No reference |
Potency (functional) | 0.0046 uM | PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 0.0126 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] | ChEMBL. | No reference |
Potency (functional) | 0.0731 uM | PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] | ChEMBL. | No reference |
Potency (functional) | 0.0953 uM | PubChem BioAssay. qHTS for Inhibitors of the Phosphatase Activity of Eya2: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 0.1648 uM | PUBCHEM_BIOASSAY: qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation in HepG2 cytotox. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540272] | ChEMBL. | No reference |
Potency (functional) | 0.1831 uM | PUBCHEM_BIOASSAY: qHTS of small molecules that selectively kill Giardia lamblia: Hit Validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540272] | ChEMBL. | No reference |
Potency (functional) | 0.1995 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of estrogen receptor alpha signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 0.3162 uM | PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 0.631 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] | ChEMBL. | No reference |
Potency (functional) | 0.7079 uM | PUBCHEM_BIOASSAY: qHTS Assay for Substrates of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] | ChEMBL. | No reference |
Potency (functional) | 1.0418 uM | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] | ChEMBL. | No reference |
Potency (functional) | 1.1689 uM | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] | ChEMBL. | No reference |
Potency (functional) | = 1.9953 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 1.9953 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-024. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 2.2387 uM | PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] | ChEMBL. | No reference |
Potency (functional) | 2.5119 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] | ChEMBL. | No reference |
Potency (functional) | = 2.5119 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-022. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 2.5929 uM | PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 3.1623 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-010. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 3.1623 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-018. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 3.6626 uM | PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 3.9811 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-009. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 3.9811 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-015. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 3.9811 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-002. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 3.9811 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-017. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 3.9811 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-008. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 3.9811 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-012. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 3.9811 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-021. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 5.0119 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-020. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 5.0119 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-016. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 5.0119 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-001. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 5.0119 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-007. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 5.0119 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-014. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 5.0119 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-019. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 5.0119 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-006. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 6.3096 um | PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 6.3096 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of estrogen receptor alpha signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 6.3096 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of vitamin D receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 6.3096 uM | PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 6.3096 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-011. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 6.3096 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-005. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 6.3096 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-023. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 6.3096 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-004. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 6.3096 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-013. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 7.6959 uM | PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 7.9433 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 7.9433 uM | PubChem BioAssay. qHTS assay for small molecule activators of the p53 signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 7.9433 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-026. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 7.9433 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-025. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 8.802 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 8.8772 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 8.9125 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] | ChEMBL. | No reference |
Potency (functional) | 8.9125 uM | PubChem BioAssay. qHTS assay for small molecule activators of the p53 signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 10 um | PUBCHEM_BIOASSAY: MultiTox-Fluor Cytotoxicity Assay - LYMP1-002 - Live Cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 10 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP1-003 - Assay at 40 hr. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 10 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP2-003. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 11.2202 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] | ChEMBL. | No reference |
Potency (functional) | 11.2202 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 12.5893 um | PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 12.5893 um | PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] | ChEMBL. | No reference |
Potency (functional) | = 12.5893 um | PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 12.5893 um | PUBCHEM_BIOASSAY: qHTS Assay for Anthrax Lethal Toxin Internalization. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 12.5893 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of androgen receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 12.5893 um | PUBCHEM_BIOASSAY: MultiTox-Fluor Cytotoxicity Assay - LYMP1-001 - Live Cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 12.5893 um | PUBCHEM_BIOASSAY: MultiTox-Fluor Cytotoxicity Assay - LYMP1-003 - Live Cells. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 12.5893 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP1-003 - Assay at 24 hr. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 12.5893 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] | ChEMBL. | No reference |
Potency (functional) | 13.3332 uM | PubChem BioAssay. qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 13.6854 uM | PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 13.9503 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 14.1254 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of farnesoid X receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 14.1254 uM | PUBCHEM_BIOASSAY: qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 14.1254 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor delta signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 14.1254 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 14.1254 uM | PubChem BioAssay. qHTS Assay for Inhibitors of the HIV-1 protein Vpr. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (ADMET) | = 15.8489 um | PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] | ChEMBL. | No reference |
Potency (ADMET) | = 15.8489 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] | ChEMBL. | No reference |
Potency (binding) | 15.8489 uM | PUBCHEM_BIOASSAY: qHTS Assay for Compounds Blocking the Interaction Between CBF-beta and RUNX1 for the Treatment of Acute Myeloid Leukemia. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1484, AID504370, AID504374, AID504375] | ChEMBL. | No reference |
Potency (functional) | 15.8489 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of retinoid X receptor alpha signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 15.8489 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of androgen receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 15.8489 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP1-002 - Assay at 24 hr. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 15.8489 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP1-002 - Assay at 40 hr. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 15.8489 um | PUBCHEM_BIOASSAY: Cell Viability - LYMP1-002 - Assay at 16 hr. CellTiter-Glo luminescent cell viability assay (Promega), as a homogeneous method to measure the number of viable cells in culture was used. The end point readout of this assay is based on quantitation of intracellular ATP, an indicator of metabolic activity, using the luciferase reaction. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 19.9526 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Mammalian Selenoprotein Thioredoxin Reductase 1 (TrxR1): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488771] | ChEMBL. | No reference |
Potency (functional) | 22.2986 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 22.2986 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 25.1189 um | PUBCHEM_BIOASSAY: qHTS Assay for Identification of Small Molecule Inducers of Hypoxia Response. (Class of assay: confirmatory) [Related pubchem assays: 914 (Primary screen.), 915 (Primary screen.)] | ChEMBL. | No reference |
Potency (functional) | 25.1189 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of thyroid hormone receptor beta signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 25.1189 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor delta signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 25.1189 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 25.1189 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of estrogen receptor alpha signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 25.1189 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of glucocorticoid receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 25.1189 uM | PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 25.1189 um | PUBCHEM_BIOASSAY: MultiTox-Fluor Cytotoxicity Assay - LYMP1-001 - Dead Cells. Luminescent cell viability assay, measuring the amount of cellular ATP in the cell line following compound treatment for 24 hours (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 28.1838 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of androgen receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 28.1838 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor delta signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 28.1838 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of vitamin D receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 28.1838 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 28.1838 uM | PubChem BioAssay. qHTS assay for environmental chemicals that activate the Aryl hydrocarbon Receptor (AhR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 29.081 uM | PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] | ChEMBL. | No reference |
Potency (functional) | = 31.6228 um | PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins. (Class of assay: confirmatory) [Related pubchem assays: 1011 (Confirmation Concentration-Response Assay for Inhibitors of the Schistosoma mansoni Redox Cascade ), 448 (Schistosoma Mansoni Peroxiredoxins (Prx2) and thioredoxin glutathione reductase (TGR) coupled assay)] | ChEMBL. | No reference |
Potency (functional) | 31.6228 uM | PUBCHEM_BIOASSAY: qHTS assay for re-activators of p53 using a Luc reporter. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504709] | ChEMBL. | No reference |
Potency (functional) | 31.6228 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of farnesoid X receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 31.6228 uM | PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 31.6228 um | PUBCHEM_BIOASSAY: qHTS Assay for Small Molecule Inhibitors of Mitochondrial Division or Activators of Mitochondrial Fusion. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 35.3409 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 35.4813 um | PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 35.4813 um | PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 35.4813 um | PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 35.4813 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] | ChEMBL. | No reference |
Potency (functional) | 35.4813 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Potency (functional) | 35.4813 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of androgen receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 35.4813 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 35.4813 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of farnesoid X receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 35.4813 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of glucocorticoid receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 35.4813 uM | PubChem BioAssay. qHTS assay for small molecule activators of the nuclear factor-kappa B (NF-kB) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 35.4813 uM | PubChem BioAssay. qHTS of alpha-syn Inhibitors. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 37.578 uM | PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 39.6531 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 39.6531 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of L3MBTL1. (Class of assay: confirmatory) [Related pubchem assays: 485292 (Probe Development Summary for Inhibitors of L3MBTL1)] | ChEMBL. | No reference |
Potency (functional) | = 39.8107 um | PUBCHEM_BIOASSAY: qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-1. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 39.8107 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] | ChEMBL. | No reference |
Potency (functional) | 39.8107 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of estrogen receptor alpha signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 39.8107 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor delta signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 39.8107 uM | PubChem BioAssay. qHTS assay for small molecule activators of the nuclear factor-kappa B (NF-kB) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 39.8107 uM | PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (binding) | = 44.6684 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 44.6684 um | PUBCHEM_BIOASSAY: Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 44.6684 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of thyroid hormone receptor beta signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 44.6684 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor gamma signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 50.1187 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of vitamin D receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 63.0957 uM | PubChem BioAssay. qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 66.8242 uM | PubChem BioAssay. qHTS assay to identify small molecules that stimulate interleukin-8 (IL-8) secretion. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 66.8242 uM | PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 79.4328 uM | PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 125.8925 uM | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] | ChEMBL. | No reference |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Homo sapiens | ChEMBL23 | ||
Plasmodium falciparum | ChEMBL23 | ||
Giardia lamblia |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.