Detailed information for compound 1294988

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 353.372 | Formula: C19H19N3O4
  • H donors: 3 H acceptors: 4 LogP: 3.15 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCN1C(=O)NC(=O)/C(=C(\C=C\c2c[nH]c3c2cccc3)/O)/C1=O
  • InChi: 1S/C19H19N3O4/c1-2-3-10-22-18(25)16(17(24)21-19(22)26)15(23)9-8-12-11-20-14-7-5-4-6-13(12)14/h4-9,11,20,23H,2-3,10H2,1H3,(H,21,24,26)/b9-8+,16-15-
  • InChiKey: OQLXZBCHTNEOPS-DBQILDTASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens G protein-coupled receptor 35 Starlite/ChEMBL No references
Homo sapiens neuropeptide S receptor 1 Starlite/ChEMBL No references
Homo sapiens karyopherin (importin) beta 1 No references
Homo sapiens polo-like kinase 1 Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens corticotropin releasing hormone binding protein No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens ATM serine/threonine kinase Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens corticotropin releasing hormone receptor 2 No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G Starlite/ChEMBL No references
Homo sapiens snurportin 1 No references
Homo sapiens apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D Starlite/ChEMBL No references
Homo sapiens RAN, member RAS oncogene family No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum ko:K06631 polo-like kinase 1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Theileria parva importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans identical to the C terminus of CaP19.5580 potential phosphatidylinositol kinase Get druggable targets OG5_128955 All targets in OG5_128955
Echinococcus granulosus GTP binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus granulosus serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 Get druggable targets OG5_130760 All targets in OG5_130760
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Brugia malayi GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania donovani importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica Ran family GTPase Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma brucei gambiense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein Get druggable targets OG5_128955 All targets in OG5_128955
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_130760 All targets in OG5_130760
Leishmania major GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Schistosoma mansoni hypothetical protein Get druggable targets OG5_131808 All targets in OG5_131808
Plasmodium knowlesi GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Entamoeba histolytica hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis serine protein kinase ATM Get druggable targets OG5_128955 All targets in OG5_128955
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Brugia malayi Importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus multilocularis serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Cryptosporidium hominis importin-beta2 Get druggable targets OG5_127843 All targets in OG5_127843
Toxoplasma gondii HEAT repeat-containing protein Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus serine protein kinase ATM Get druggable targets OG5_128955 All targets in OG5_128955
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania major phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Trypanosoma brucei polo-like protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana phosphatidylinositol 3-kinase-like protein Get druggable targets OG5_128955 All targets in OG5_128955
Plasmodium vivax importin-beta 2, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Neospora caninum GTP-binding nuclear protein Ran, related Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania mexicana protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei gambiense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma congolense importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Echinococcus granulosus neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma japonicum IPR001879,Hormone receptor, extracellular,domain-containing Get druggable targets OG5_130760 All targets in OG5_130760
Neospora caninum phosphatidylinositol 3- and 4-kinase domain- containing protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Trichomonas vaginalis PIKK family atypical protein kinase Get druggable targets OG5_128955 All targets in OG5_128955
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma brucei gambiense polo-like protein kinase,protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Cryptosporidium hominis GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Trichomonas vaginalis importin beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Babesia bovis importin beta subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Cryptosporidium parvum GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Toxoplasma gondii FATC domain-containing protein Get druggable targets OG5_128955 All targets in OG5_128955
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica serine/threonine protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei gambiense phosphatidylinositol kinase domain protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Echinococcus multilocularis neuropeptide receptor A26 Get druggable targets OG5_136011 All targets in OG5_136011
Candida albicans similar to putative phosphatidylinositol kinase involved in telomere length regulation Get druggable targets OG5_128955 All targets in OG5_128955
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) nucleolar RNA-associated protein alpha Get druggable targets OG5_131808 All targets in OG5_131808
Leishmania braziliensis importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum IPR000971,Globin;IPR012292,Globin-related;IPR009050,Globin-like,domain-containing Get druggable targets OG5_128955 All targets in OG5_128955
Plasmodium knowlesi importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi serine/threonine-protein kinase plk-2 Get druggable targets OG5_127396 All targets in OG5_127396
Cryptosporidium parvum importin/karyopherin Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania infantum phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Leishmania donovani GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Importin subunit beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Babesia bovis GTP-binding nuclear protein Ran Get druggable targets OG5_127514 All targets in OG5_127514
Trypanosoma congolense GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans similar to putative phosphatidylinositol kinase involved in telomere length regulation Get druggable targets OG5_128955 All targets in OG5_128955
Plasmodium yoelii importin beta-1 subunit Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Theileria parva GTP-binding nuclear protein ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Candida albicans Ran, Ras family GTP-binding protein Get druggable targets OG5_127514 All targets in OG5_127514
Onchocerca volvulus Serine\/threonine kinase homolog Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Neospora caninum hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus importin subunit beta 1 Get druggable targets OG5_127843 All targets in OG5_127843
Echinococcus granulosus neuropeptide s receptor Get druggable targets OG5_136011 All targets in OG5_136011
Leishmania braziliensis phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania infantum protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania donovani phosphatidylinositol 3-kinase-like protein Get druggable targets OG5_128955 All targets in OG5_128955
Brugia malayi RNA, U transporter 1 Get druggable targets OG5_131808 All targets in OG5_131808
Schistosoma japonicum ko:K07936 GTP-binding nuclear protein Ran, putative Get druggable targets OG5_127514 All targets in OG5_127514
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 Get druggable targets OG5_130760 All targets in OG5_130760
Trichomonas vaginalis Importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative Get druggable targets OG5_127514 All targets in OG5_127514
Schistosoma japonicum Snurportin-1, putative Get druggable targets OG5_131808 All targets in OG5_131808
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128955 All targets in OG5_128955
Giardia lamblia Kinase, PLK Get druggable targets OG5_127396 All targets in OG5_127396
Plasmodium yoelii GTP-binding nuclear protein ran/tc4 Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium berghei importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni importin beta-1 Get druggable targets OG5_127843 All targets in OG5_127843
Giardia lamblia GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Loa Loa (eye worm) PLK/PLK1 protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative Get druggable targets OG5_130760 All targets in OG5_130760
Leishmania braziliensis protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans karyopherin-beta Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum IPR000276,Rhodopsin-like GPCR superfamily,domain-containing Get druggable targets OG5_136011 All targets in OG5_136011
Schistosoma japonicum ko:K04728 ataxia telangectasia mutated family protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Echinococcus multilocularis snurportin 1 Get druggable targets OG5_131808 All targets in OG5_131808
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Entamoeba histolytica hypothetical protein Get druggable targets OG5_127843 All targets in OG5_127843
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 Get druggable targets OG5_127514 All targets in OG5_127514
Leishmania infantum importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Leishmania major protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum Importin subunit beta-1, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma mansoni ataxia telangiectasia mutated (atm) Get druggable targets OG5_128955 All targets in OG5_128955
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative Get druggable targets OG5_128955 All targets in OG5_128955
Schistosoma mansoni ran Get druggable targets OG5_127514 All targets in OG5_127514
Plasmodium falciparum importin beta, putative Get druggable targets OG5_127843 All targets in OG5_127843
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania mexicana importin beta-1 subunit, putative Get druggable targets OG5_127843 All targets in OG5_127843
Schistosoma japonicum Serine/threonine-protein kinase PLK1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Loa Loa (eye worm) pigment dispersing factor receptor c corticotropin releasing hormone receptor 2 438 aa 383 aa 26.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0088 0.0133
Loa Loa (eye worm) hypothetical protein 0.0018 0.0099 0.0135
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0031 0.0056
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Plasmodium falciparum multidrug resistance-associated protein 1 0.0196 0.1932 0.3082
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0009 0.0007 0.0005
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0088 0.0088
Schistosoma mansoni hypothetical protein 0.0098 0.0925 0.1328
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0116 0.0136
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0038 0.005
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0038
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0432 0.4366 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0616 0.6257 1
Trichomonas vaginalis abca2, putative 0.0012 0.0031 0.0039
Giardia lamblia ABC-type transport system ATP-binding chain, putative 0.0012 0.0031 0.0063
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.3741 0.5367
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0432 0.4366 0.6975
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1086 0.1727
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0038 0.005
Schistosoma mansoni calpain-7 (C02 family) 0.0009 0.0007 0.001
Trypanosoma cruzi ABC transporter, putative 0.0076 0.0698 0.1585
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Leishmania major ATP-binding cassette protein subfamily F, member 3, putative 0.0012 0.0031 0.0039
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0059 0.0521 0.0521
Entamoeba histolytica ABC transporter, putative 0.0196 0.1932 0.308
Mycobacterium tuberculosis Probable O-antigen/lipopolysaccharide transport integral membrane protein ABC transporter RfbD 0.0065 0.0578 0.0878
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0098 0.0925 0.1322
Echinococcus granulosus mothers against decapentaplegic 2 0.0015 0.0063 0.009
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0284 0.2833 0.2833
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Plasmodium falciparum ABC transporter B family member 7, putative 0.0196 0.1932 0.3082
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0196 0.1932 0.3082
Brugia malayi hypothetical protein 0.0365 0.3671 0.5267
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0616 0.6257 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0009 0.0007 0.0004
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0116 0.0174
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0184 0.1812 0.2888
Brugia malayi MH1 domain containing protein 0.0018 0.0099 0.0135
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0012 0.0031 0.0045
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0114 0.1086 0.1727
Brugia malayi P-glycoprotein related protein 2 0.0012 0.0031 0.0038
Trypanosoma cruzi glycosomal transporter (GAT3), putative 0.0012 0.0031 0.0056
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0432 0.4366 0.6267
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0009 0.0007 0.0007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0009 0.0007 0.001
Trichomonas vaginalis ABC transporter, putative 0.0616 0.6257 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0116 0.025
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0588 0.0933
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0188 0.1852 0.2654
Schistosoma mansoni ran 0.0026 0.0175 0.0252
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0196 0.1932 0.4416
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0616 0.6257 0.8981
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0012 0.0031 0.0039
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0088 0.0088
Brugia malayi ABC transporter transmembrane region family protein 0.0196 0.1932 0.2768
Schistosoma mansoni peptidase 0.001 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0014 0.0053 0.0069
Brugia malayi ABC transporter family protein 0.0196 0.1932 0.2768
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0098 0.0925 0.1328
Giardia lamblia ABC transporter, ATP-binding protein, putative 0.0012 0.0031 0.0063
Plasmodium falciparum protein GCN20 0.0012 0.0031 0.0042
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0059 0.0521 0.0747
Entamoeba histolytica ABC transporter ATP-binding protein, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0116 0.0174
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0088 0.0126
Trypanosoma cruzi ABC transporter, putative 0.0065 0.0578 0.131
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0196 0.1932 0.4384
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0038
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.025 0.0359
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.025 0.0359
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0616 0.6257 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0004
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0022 0.0136 0.0297
Giardia lamblia ABC transporter 0.0012 0.0031 0.0063
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0136 0.0189
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0009 0.0007 0.0007
Entamoeba histolytica ATP-binding cassette protein, putative 0.0196 0.1932 0.308
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0196 0.1932 0.2768
Brugia malayi RE11181p 0.0065 0.0578 0.0824
Schistosoma mansoni DNA helicase recq5 0.0009 0.0005 0.0007
Trypanosoma brucei ATP-binding cassette protein, putative 0.0432 0.4366 1
Schistosoma mansoni DNA helicase recq1 0.0009 0.0005 0.0007
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Leishmania major ATP-binding cassette protein subfamily F, member 2, putative 0.0012 0.0031 0.0039
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0009 0.0007 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.1852 0.1852
Treponema pallidum ribose/galactose ABC transporter, ATP-binding protein (rbsA-1) 0.0012 0.0031 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trypanosoma brucei ABC transporter, putative 0.0076 0.0698 0.1585
Echinococcus multilocularis geminin 0.0205 0.2019 0.2019
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.0611 0.0966
Brugia malayi MH2 domain containing protein 0.0483 0.4888 0.7014
Brugia malayi Pax transcription factor protein 2 0.0261 0.2597 0.3724
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0012 0.0038 0.005
Echinococcus granulosus ATP binding cassette sub family F 0.0012 0.0031 0.0045
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0022 0.0136 0.0207
Schistosoma mansoni multidrug resistance protein 0.0616 0.6257 0.8981
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0493 0.0778
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0196 0.1932 0.308
Plasmodium falciparum ABC transporter B family member 3, putative 0.0196 0.1932 0.3082
Schistosoma mansoni multidrug resistance protein 0.0184 0.1812 0.2601
Echinococcus multilocularis multidrug resistance associated protein 7 0.0196 0.1932 0.1932
Leishmania major ATP-binding cassette protein subfamily D, member 1, putative 0.0012 0.0031 0.0039
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Echinococcus multilocularis tar DNA binding protein 0.0685 0.6967 0.6967
Toxoplasma gondii LsmAD domain-containing protein 0.0132 0.127 0.2024
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0202 0.0312
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Loa Loa (eye worm) latrophilin receptor protein 2 0.0098 0.0925 0.1322
Leishmania major ATP-binding cassette protein subfamily D, member 2, putative 0.0012 0.0031 0.0039
Entamoeba histolytica P-glycoprotein-2 0.0616 0.6257 1
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0009 0.0007 0.001
Trichomonas vaginalis metal ABC transporter, putative 0.0012 0.0031 0.0039
Mycobacterium ulcerans glutaminase 0.0281 0.2808 0.6407
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0116 0.025
Trypanosoma cruzi hypothetical protein 0.0012 0.0031 0.0056
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0007 0.001
Schistosoma mansoni multidrug resistance protein 0.0012 0.0031 0.0045
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0616 0.6257 1
Leishmania major ATP-binding cassette protein subfamily H, member 1, putative 0.0012 0.0031 0.0039
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0009 0.0007 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0053 0.0073
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0316 0.0316
Schistosoma mansoni hypothetical protein 0.0356 0.3579 0.5138
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0116 0.0166
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Toxoplasma gondii ABC transporter, ATP-binding domain-containing protein 0.0012 0.0031 0.0042
Entamoeba histolytica ABC transporter, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0184 0.1812 0.2888
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0202 0.0312
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0022 0.0136 0.0297
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0009 0.0007 0.0007
Brugia malayi ABC transporter family protein 0.0616 0.6257 0.898
Entamoeba histolytica ABC transporter, putative 0.0012 0.0031 0.0039
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0175 0.0386
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1086 0.1727
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0114 0.1086 0.156
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0137 0.0209
Trichomonas vaginalis abca12, putative 0.0012 0.0031 0.0039
Entamoeba histolytica hypothetical protein 0.003 0.022 0.0341
Toxoplasma gondii ABC transporter, ATP-binding domain-containing protein 0.0012 0.0031 0.0042
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0616 0.6257 1
Trypanosoma cruzi multidrug resistance protein E, putative 0.0012 0.0031 0.0056
Trichomonas vaginalis abca12, putative 0.0012 0.0031 0.0039
Entamoeba histolytica P-glycoprotein 5, putative 0.0184 0.1812 0.2888
Giardia lamblia Multidrug resistance-associated protein 1 0.0196 0.1932 0.4544
Entamoeba histolytica ABC transporter, putative 0.0432 0.4366 0.6975
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0616 0.6257 0.8981
Brugia malayi ABC transporter family protein 0.0368 0.3699 0.5307
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0116 0.0116
Leishmania major ATP-binding cassette protein subfamily A, member 5, putative 0.0012 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0365 0.3671 0.5267
Echinococcus granulosus multidrug resistance protein 1 0.0616 0.6257 0.8981
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0022 0.0031
Schistosoma mansoni ATP-binding cassette sub-family E (oabp) member 0.0012 0.0031 0.0045
Toxoplasma gondii ATP-binding cassette G family transporter ABCG107 0.0076 0.0698 0.1109
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0009 0.0007 0.001
Giardia lamblia Hypothetical protein 0.0184 0.1812 0.4261
Echinococcus multilocularis ATP binding cassette sub family A 0.0012 0.0031 0.0031
Onchocerca volvulus 0.0365 0.3671 0.5863
Loa Loa (eye worm) hypothetical protein 0.0065 0.0578 0.0824
Leishmania major p-glycoprotein e 0.0196 0.1932 0.308
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0616 0.6257 1
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.003 0.022 0.0316
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0175 0.0386
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0088 0.0133
Brugia malayi hypothetical protein 0.0196 0.1932 0.2768
Brugia malayi hypothetical protein 0.0012 0.0031 0.0038
Echinococcus multilocularis cpg binding protein 0.0037 0.0289 0.0289
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.025 0.0359
Treponema pallidum excinuclease ABC subunit A 0.0012 0.0031 0.5
Entamoeba histolytica ATP-binding cassette protein, putative 0.0196 0.1932 0.308
Echinococcus multilocularis ATP binding cassette sub family E 0.0012 0.0031 0.0031
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0009 0.0007 0.0007
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Schistosoma mansoni multidrug resistance protein 0.0012 0.0031 0.0045
Echinococcus granulosus multidrug resistance associated protein 7 0.0196 0.1932 0.2773
Schistosoma mansoni cpg binding protein 0.0037 0.0289 0.0415
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0088 0.0185
Brugia malayi RNA, U transporter 1 0.0099 0.0931 0.1331
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.025 0.025
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Leishmania major GTP-binding protein, putative 0.0026 0.0175 0.0269
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0064 0.0092
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0004
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0009 0.0007 0.0005
Schistosoma mansoni ATP-binding cassette transporter 0.0012 0.0031 0.0045
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.1852 0.2659
Brugia malayi ABC transporter family protein 0.0012 0.0031 0.0038
Trypanosoma brucei glycosomal transporter (GAT3), putative 0.0012 0.0031 0.0056
Loa Loa (eye worm) multidrug resistance-associated protein 0.0012 0.0031 0.0038
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0196 0.1932 0.308
Brugia malayi hypothetical protein 0.0012 0.0031 0.0038
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0175 0.0245
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0031 0.0039
Echinococcus multilocularis ATP binding cassette sub family B 0.0196 0.1932 0.1932
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0196 0.1932 0.4416
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0022 0.0136 0.0297
Entamoeba histolytica P-glycoprotein 5, putative 0.0616 0.6257 1
Mycobacterium ulcerans antibiotic resistance ABC transporter efflux protein 0.0065 0.0578 0.1261
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.0137 0.0298
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0196 0.1932 0.4384
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0012 0.0038 0.0055
Trypanosoma cruzi ABC transporter, putative 0.0432 0.4366 1
Trypanosoma brucei ATP-binding cassette protein subfamily G 0.0076 0.0698 0.1585
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.009 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Loa Loa (eye worm) hypothetical protein 0.0015 0.0063 0.0084
Plasmodium falciparum ubiquitin specific protease, putative 0.0009 0.0007 0.0004
Trypanosoma cruzi glycosomal transporter (GAT1), putative 0.0012 0.0031 0.0056
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0175 0.0269
Trypanosoma brucei ABC transporter family-like protein 0.0012 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0184 0.1812 0.2596
Echinococcus granulosus multidrug resistance protein 1 0.0616 0.6257 0.8981
Echinococcus multilocularis dna polymerase eta 0.0046 0.0386 0.0386
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0052 0.0104
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0009 0.0007 0.001
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.0611 0.0966
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trypanosoma cruzi glycosomal transporter (GAT2), putative 0.0012 0.0031 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0031 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0031 0.0039
Brugia malayi MH1 domain containing protein 0.0018 0.0099 0.0135
Mycobacterium tuberculosis Probable conserved integral membrane protein ABC transporter 0.0065 0.0578 0.0878
Toxoplasma gondii ATP-binding cassette sub-family F member 1 0.0012 0.0031 0.0042
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0616 0.6257 1
Loa Loa (eye worm) hypothetical protein 0.0196 0.1932 0.2768
Plasmodium vivax CCR4-associated factor 16, putative 0.0012 0.0031 0.0039
Echinococcus granulosus tar DNA binding protein 0.0685 0.6967 1
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Schistosoma mansoni Smad4 0.0033 0.025 0.0359
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0616 0.6257 1
Schistosoma mansoni DNA polymerase eta 0.0046 0.0386 0.0554
Loa Loa (eye worm) RecQ helicase 0.0022 0.0137 0.0191
Leishmania major phosphatidylinositol kinase related protein, putative 0.0022 0.0137 0.0208
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0616 0.6257 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0022 0.0136 0.0297
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0022 0.0136 0.0297
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0009 0.0007 0.001
Leishmania major ATP-binding cassette protein subfamily G, member 2, putative 0.0076 0.0698 0.1106
Echinococcus granulosus mothers against decapentaplegic 6 0.0015 0.0063 0.009
Leishmania major ABC transporter family-like protein 0.0012 0.0031 0.0039
Giardia lamblia ABC transporter family protein 0.0012 0.0031 0.0063
Leishmania major ATP-binding cassette protein subfamily G, member 3, putative 0.0012 0.0031 0.0039
Brugia malayi latrophilin 2 splice variant baaae 0.0213 0.2102 0.3013
Trichomonas vaginalis abca6, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trypanosoma brucei p-glycoprotein 0.0196 0.1932 0.4416
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0116 0.016
Entamoeba histolytica P-glycoprotein-1 0.0616 0.6257 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0196 0.1932 0.308
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0009 0.0007 0.0007
Treponema pallidum thiamine ABC transporter, ATP-binding protein 0.0012 0.0031 0.5
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0022 0.0136 0.0297
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0009 0.0007 0.0007
Treponema pallidum spermidine/putrescine ABC transporter, ATP-binding protein (potA) 0.0012 0.0031 0.5
Leishmania major ATP-binding cassette protein subfamily G, member 5, putative 0.0076 0.0698 0.1106
Toxoplasma gondii ubiquitin-specific protease USP4 0.0009 0.0007 0.0004
Trichomonas vaginalis abca4, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0431 0.4356 0.6959
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0116 0.025
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0022 0.0136 0.0196
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0005 0.0005
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0616 0.6257 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trypanosoma cruzi ATP-binding cassette protein subfamily G 0.0076 0.0698 0.1585
Brugia malayi hypothetical protein 0.0009 0.0007 0.0003
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.1086 0.2477
Schistosoma mansoni hypothetical protein 0.0012 0.0031 0.0045
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0116 0.025
Leishmania major ATP-binding cassette protein subfamily A, member 3, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0038 0.005
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0116 0.0195
Plasmodium vivax ABC transporter B family member 6, putative 0.0196 0.1932 0.308
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0245 0.0546
Toxoplasma gondii ABC transporter family protein 0.0196 0.1932 0.3082
Brugia malayi multidrug resistance protein 3 0.0616 0.6257 0.898
Onchocerca volvulus 0.0261 0.2597 0.4145
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.022 0.0341
Brugia malayi ATP-binding cassette, sub-family F, member 2 0.0012 0.0031 0.0038
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.001 0.0009 0.0009
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0009 0.0007 0.001
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0196 0.1932 0.308
Brugia malayi ABC transporter family protein 0.0012 0.0031 0.0038
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0009 0.0007 0.001
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0032 0.0058
Trichomonas vaginalis taga, putative 0.0616 0.6257 1
Brugia malayi Importin beta-1 subunit 0.0035 0.027 0.0381
Plasmodium falciparum multidrug resistance protein 2 0.0196 0.1932 0.3082
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Schistosoma mansoni smad 0.0033 0.025 0.0359
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Plasmodium vivax ABC transporter G family member 2, putative 0.0432 0.4366 0.6975
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0038
Leishmania major ATP-binding cassette protein subfamily A, member 8, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Toxoplasma gondii ATP-binding protein 0.0012 0.0031 0.0042
Giardia lamblia Multidrug resistance-associated protein 1 0.0196 0.1932 0.4544
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis ATP-dependent transporter, putative 0.0012 0.0031 0.0039
Plasmodium falciparum ABC transporter F family member 1, putative 0.0012 0.0031 0.0042
Plasmodium vivax importin-beta 2, putative 0.0035 0.027 0.0421
Trypanosoma brucei ABC transporter, putative 0.0012 0.0031 0.0056
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0196 0.1932 0.4384
Plasmodium vivax ABC transporter I family member 1, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1086 0.1727
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.0611 0.0871
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0116 0.025
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.1852 0.2659
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0009 0.0007 0.0007
Schistosoma mansoni multidrug resistance protein 0.0196 0.1932 0.2773
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Onchocerca volvulus 0.0012 0.0031 0.0039
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0088 0.0091
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0116 0.0174
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0432 0.4366 0.6976
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0196 0.1932 0.308
Schistosoma mansoni Smad4 0.0015 0.0063 0.009
Plasmodium vivax ABC transporter F family member 1, putative 0.0012 0.0031 0.0039
Echinococcus granulosus neuropeptide s receptor 0.0561 0.5694 0.8173
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.025 0.0353
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0184 0.1812 0.4261
Loa Loa (eye worm) ABC transporter 0.0012 0.0031 0.0038
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.003 0.022 0.031
Trypanosoma brucei PAB1-binding protein , putative 0.0132 0.127 0.2898
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0616 0.6257 0.6257
Schistosoma mansoni ABC transporter 0.0368 0.3699 0.531
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0196 0.1932 0.308
Entamoeba histolytica protein kinase rad3, putative 0.0012 0.0038 0.005
Treponema pallidum methylgalactoside ABC transporter, ATP binding protein (mglA) 0.0012 0.0031 0.5
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0038
Giardia lamblia DINP protein human, muc B family 0.002 0.0116 0.0262
Trichomonas vaginalis peroxisomal membrane protein, putative 0.0012 0.0031 0.0039
Loa Loa (eye worm) TAR-binding protein 0.0685 0.6967 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0116 0.025
Treponema pallidum ABC transporter, ATP-binding protein 0.0012 0.0031 0.5
Loa Loa (eye worm) hypothetical protein 0.0035 0.027 0.0381
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0196 0.1932 0.3082
Trypanosoma brucei glycosomal transporter (GAT2) 0.0012 0.0031 0.0056
Brugia malayi ABC transporter family protein 0.0196 0.1932 0.2768
Trichomonas vaginalis conserved hypothetical protein 0.0184 0.1812 0.2888
Brugia malayi hypothetical protein 0.0132 0.127 0.1818
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0009 0.0007 0.0007
Leishmania major ABC transporter-like protein 0.0012 0.0031 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0009 0.0007 0.001
Brugia malayi ABC transporter 0.0012 0.0031 0.0038
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.0611 0.0877
Echinococcus granulosus ATP binding cassette sub family E 0.0012 0.0031 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0116 0.025
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1086 0.1727
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.027 0.0424
Entamoeba histolytica hypothetical protein 0.0196 0.1932 0.308
Giardia lamblia ATP-binding cassette protein 5 0.0012 0.0031 0.0063
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0196 0.1932 0.3082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0009 0.0007 0.001
Trypanosoma cruzi ATP-binding cassette sub-family F member 1, putative 0.0012 0.0031 0.0056
Giardia lamblia ABC transporter 0.0421 0.4246 1
Brugia malayi Smad1 0.0033 0.025 0.0353
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.1086 0.2477
Toxoplasma gondii hypothetical protein 0.0009 0.0007 0.0004
Trichomonas vaginalis abcb9, putative 0.0616 0.6257 1
Brugia malayi ABC transporter family protein 0.0012 0.0031 0.0038
Echinococcus granulosus Smad4 0.0033 0.025 0.0359
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0088 0.0119
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Brugia malayi RNA recognition motif domain containing protein 0.0685 0.6967 1
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0116 0.0195
Trichomonas vaginalis abca2, putative 0.0012 0.0031 0.0039
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0616 0.6257 0.6257
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0009 0.0007 0.0007
Entamoeba histolytica ATP-binding cassette sub-family G1, putative 0.0065 0.0578 0.0914
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Trypanosoma brucei atp-binding cassette sub-family e member 1 0.0012 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0132 0.127 0.1818
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0052 0.0104
Echinococcus granulosus ATP binding cassette sub family G 0.0432 0.4366 0.6267
Echinococcus multilocularis multidrug resistance protein 1 0.0431 0.4356 0.4356
Toxoplasma gondii ATP-binding cassette G family transporter ABCG89 0.0076 0.0698 0.1109
Trichomonas vaginalis abca10, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Trypanosoma cruzi ABC transporter family-like protein 0.0012 0.0031 0.0056
Plasmodium vivax ataxin-2 like protein, putative 0.0132 0.127 0.2021
Trichomonas vaginalis glutaminase, putative 0.0281 0.2808 0.4483
Brugia malayi ATP-binding cassette, sub-family F 0.0012 0.0031 0.0038
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0114 0.1086 0.1554
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0009 0.0007 0.001
Loa Loa (eye worm) ABC transporter 0.0196 0.1932 0.2768
Echinococcus granulosus ATP binding cassette sub family A 0.0012 0.0031 0.0045
Schistosoma mansoni hypothetical protein 0.0098 0.0925 0.1328
Brugia malayi ubiquitin specific protease 14 0.0009 0.0007 0.0003
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.011 0.0168
Schistosoma mansoni cpg binding protein 0.0035 0.0269 0.0385
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0196 0.1932 0.3082
Brugia malayi RNA binding protein 0.0685 0.6967 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0116 0.025
Loa Loa (eye worm) ABC transporter 0.0196 0.1932 0.2768
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0616 0.6257 0.8981
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0022 0.0136 0.0207
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0022 0.0136 0.0207
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0196 0.1932 0.4416
Entamoeba histolytica P-glycoprotein-2, putative 0.0616 0.6257 1
Trichomonas vaginalis ran, putative 0.0026 0.0175 0.0269
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0009 0.0007 0.001
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0009 0.0007 0.0007
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0116 0.025
Leishmania major ATP-binding cassette protein subfamily H, member 3, putative 0.0012 0.0031 0.0039
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0004
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0009 0.0007 0.001
Echinococcus granulosus serine protein kinase ATM 0.003 0.022 0.0316
Loa Loa (eye worm) multidrug resistance protein 3 0.0616 0.6257 0.898
Loa Loa (eye worm) hypothetical protein 0.0046 0.0386 0.0547
Leishmania major ATP-binding cassette protein subfamily A, member 6, putative 0.0012 0.0031 0.0039
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0311 0.3116 0.4469
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0088 0.0126
Brugia malayi MH1 domain containing protein 0.0033 0.025 0.0353
Schistosoma mansoni multidrug resistance protein 0.0196 0.1932 0.2773
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis ABC transporter, putative 0.0616 0.6257 1
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Loa Loa (eye worm) ABC transporter 0.0368 0.3699 0.5307
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0196 0.1932 0.4416
Leishmania major hypothetical protein, conserved 0.0132 0.127 0.2021
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0196 0.1932 0.308
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0136 0.0189
Leishmania major ABC-thiol transporter 0.0196 0.1932 0.308
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0022 0.0136 0.0297
Giardia lamblia RNase L inhibitor 0.0012 0.0031 0.0063
Schistosoma mansoni hypothetical protein 0.001 0.0009 0.0013
Entamoeba histolytica hypothetical protein 0.0028 0.0202 0.0312
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0685 0.6967 1
Trichomonas vaginalis ATP-dependent transporter, putative 0.0012 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0616 0.6257 0.898
Brugia malayi ATP-binding cassette sub-family E member 1 (Ribonuclease 4 inhibitor) 0.0012 0.0031 0.0038
Plasmodium falciparum multidrug resistance-associated protein 2 0.0196 0.1932 0.3082
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0022 0.0136 0.0207
Plasmodium falciparum ABC transporter B family member 4, putative 0.0196 0.1932 0.3082
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0616 0.6257 1
Brugia malayi ABC transporter family protein 0.0196 0.1932 0.2768
Giardia lamblia ABC transporter, ATP-binding protein 0.0012 0.0031 0.0063
Loa Loa (eye worm) hypothetical protein 0.0616 0.6257 0.898
Schistosoma mansoni tar DNA-binding protein 0.0685 0.6967 1
Brugia malayi P-glycoprotein-like protein 0.0196 0.1932 0.2768
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0012 0.0038 0.0048
Plasmodium falciparum multidrug resistance protein 1 0.0616 0.6257 1
Echinococcus multilocularis Smad4 0.0033 0.025 0.025
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.002 0.0023
Trypanosoma brucei ABC transporter, putative 0.0432 0.4366 1
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0196 0.1932 0.3053
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0616 0.6257 0.6257
Leishmania major ATP-binding cassette protein subfamily A, member 2, putative 0.0012 0.0031 0.0039
Schistosoma mansoni kinase 0.0058 0.0509 0.073
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Echinococcus granulosus GPCR family 2 0.0098 0.0925 0.1328
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0184 0.1812 0.2888
Echinococcus multilocularis mothers against decapentaplegic 2 0.0015 0.0063 0.0063
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0004
Echinococcus granulosus geminin 0.0205 0.2019 0.2899
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0616 0.6257 1
Giardia lamblia ABC-type multidrug transport system, ATPase component 0.0012 0.0031 0.0063
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0616 0.6257 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0188 0.1852 0.2659
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0012 0.0038 0.0038
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0604 0.6137 0.8809
Schistosoma mansoni ATP-dependent transporter 0.0012 0.0031 0.0045
Trichomonas vaginalis abca5, putative 0.0012 0.0031 0.0039
Echinococcus multilocularis 0.0196 0.1932 0.1932
Echinococcus multilocularis neuropeptide s receptor 0.0561 0.5694 0.5694
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1086 0.1727
Giardia lamblia MRP-like ABC transporter 0.0196 0.1932 0.4544
Loa Loa (eye worm) MH2 domain-containing protein 0.0015 0.0063 0.0084
Treponema pallidum ABC transporter, ATP-binding protein (natA) 0.0012 0.0031 0.5
Schistosoma mansoni multidrug resistance protein 0.0196 0.1932 0.2773
Brugia malayi MH2 domain containing protein 0.0033 0.025 0.0353
Schistosoma mansoni hypothetical protein 0.0098 0.0925 0.1328
Schistosoma mansoni hypothetical protein 0.0009 0.0007 0.001
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0015 0.0063 0.0089
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0098 0.0925 0.0925
Brugia malayi hypothetical protein 0.0065 0.0578 0.0824
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0018 0.0092 0.0125
Echinococcus multilocularis multidrug resistance associated protein 1 0.0196 0.1932 0.1932
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trypanosoma cruzi ABC transporter family-like protein 0.0012 0.0031 0.0056
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0012 0.0038 0.0072
Toxoplasma gondii ATP-binding cassette G family transporter ABCG96 0.0076 0.0698 0.1109
Schistosoma mansoni ran 0.0026 0.0175 0.0252
Echinococcus granulosus multidrug resistance protein 1 0.0431 0.4356 0.6253
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0009 0.0007 0.0003
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0004
Trichomonas vaginalis abca4, putative 0.0012 0.0031 0.0039
Echinococcus granulosus dna polymerase kappa 0.002 0.0116 0.0166
Trypanosoma brucei unspecified product 0.0014 0.0052 0.0104
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0196 0.1932 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0116 0.025
Plasmodium vivax ABC transporter B family member 3, putative 0.0196 0.1932 0.308
Giardia lamblia ABC transporter, ATP-binding protein 0.0012 0.0031 0.0063
Echinococcus granulosus dna polymerase eta 0.0046 0.0386 0.0554
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0088 0.0129
Trypanosoma brucei unspecified product 0.0014 0.0052 0.0104
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0052 0.0104
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Brugia malayi ABC transporter 0.0184 0.1812 0.2596
Plasmodium falciparum ataxin-2 like protein, putative 0.0132 0.127 0.2024
Trichomonas vaginalis ABC transporter, putative 0.0616 0.6257 1
Plasmodium vivax ABC transporter B family member 4, putative 0.0196 0.1932 0.308
Brugia malayi glutaminase DH11.1 0.0281 0.2808 0.4027
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0014 0.0053 0.0105
Plasmodium falciparum FeS assembly ATPase SufC 0.0012 0.0031 0.0042
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0616 0.6257 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0175 0.0273
Mycobacterium ulcerans antibiotic ABC transporter integral membrane protein 0.0065 0.0578 0.1261
Entamoeba histolytica P-glycoprotein-2, putative 0.0184 0.1812 0.2888
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0009 0.0007 0.001
Toxoplasma gondii iron-sulfur assembly ATPase 0.0012 0.0031 0.0042
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0188 0.1852 0.1852
Brugia malayi MH1 domain containing protein 0.0033 0.025 0.0353
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0088 0.0088
Entamoeba histolytica multidrug resistance protein, putative 0.0196 0.1932 0.308
Treponema pallidum ribose/galactose ABC transporter, ATP-binding protein (rbsA-2) 0.0012 0.0031 0.5
Treponema pallidum ABC transporter, ATP-binding protein 0.0012 0.0031 0.5
Entamoeba histolytica P-glycoprotein 6, putative 0.0196 0.1932 0.308
Trypanosoma brucei ABC transporter, putative 0.0012 0.0031 0.0056
Trypanosoma cruzi PAB1-binding protein , putative 0.0132 0.127 0.2898
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Giardia lamblia ABC transporter, putative 0.0196 0.1932 0.4544
Trichomonas vaginalis abca6, putative 0.0012 0.0031 0.0039
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0009 0.0007 0.001
Loa Loa (eye worm) nuclear factor I 0.0018 0.0099 0.0135
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0032 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0038 0.005
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0007 0.001
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.001 0.0009 0.0013
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0009 0.0007 0.0005
Brugia malayi Calcitonin receptor-like protein seb-1 0.0311 0.3116 0.4469
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0245 0.0384
Schistosoma mansoni multidrug resistance protein 0.0196 0.1932 0.2773
Trypanosoma cruzi DNA polymerase eta, putative 0.0046 0.0386 0.0869
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Leishmania major DNA polymerase kappa, putative 0.002 0.0116 0.0174
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Entamoeba histolytica serine/threonine protein kinase, putative 0.0114 0.1086 0.1727
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0014 0.0053 0.0077
Trichomonas vaginalis abcb9, putative 0.0616 0.6257 1
Schistosoma mansoni tar DNA-binding protein 0.0685 0.6967 1
Giardia lamblia ABC transporter ABCA.1, putative 0.0012 0.0031 0.0063
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0137 0.0191
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0088 0.0185
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.1852 0.2659
Brugia malayi MH2 domain containing protein 0.0015 0.0063 0.0084
Giardia lamblia Multidrug resistance-associated protein 1 0.0184 0.1812 0.4261
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.001
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0022 0.0136 0.0136
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Trypanosoma brucei unspecified product 0.002 0.0116 0.025
Trypanosoma brucei glycosomal transporter (GAT1) 0.0012 0.0031 0.0056
Trypanosoma cruzi ABC transporter, putative 0.0065 0.0578 0.131
Trichomonas vaginalis abcb9, putative 0.0616 0.6257 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0116 0.025
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.0611 0.0611
Echinococcus multilocularis smad 0.0033 0.025 0.025
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0196 0.1932 1
Schistosoma mansoni multidrug resistance protein 0.0616 0.6257 0.8981
Trichomonas vaginalis ATP-dependent transporter, putative 0.0012 0.0031 0.0039
Trypanosoma cruzi ATP-binding cassette transporter ABCA1, putative 0.0012 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0038
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0022 0.0136 0.0136
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0196 0.1932 0.2773
Leishmania major ATP-binding cassette protein subfamily A, member 9, putative 0.0012 0.0031 0.0039
Schistosoma mansoni hypothetical protein 0.0205 0.2019 0.2899
Giardia lamblia Hypothetical protein 0.0009 0.0007 0.0005
Toxoplasma gondii ATP-binding cassette G family transporter ABCG87 0.0076 0.0698 0.1109
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0038 0.005
Entamoeba histolytica non-transporter ABC protein, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0009 0.0007 0.0007
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0432 0.4366 1
Schistosoma mansoni glutaminase 0.0281 0.2808 0.4031
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0009 0.0007 0.0004
Trichomonas vaginalis RNAse L inhibitor, putative 0.0012 0.0031 0.0039
Giardia lamblia DUB-1 0.0009 0.0007 0.0005
Trichomonas vaginalis abca2, putative 0.0012 0.0031 0.0039
Echinococcus granulosus smad 0.0033 0.025 0.0359
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0009 0.0007 0.001
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.001
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0022 0.0025
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0009 0.0007 0.0004
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0137 0.0209
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0009 0.0007 0.001
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0038
Entamoeba histolytica P-glycoprotein 6, putative 0.0196 0.1932 0.308
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0616 0.6257 1
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0616 0.6257 0.6257
Trichomonas vaginalis peroxisomal long-chain fatty acid import protein, putative 0.0012 0.0031 0.0039
Echinococcus granulosus ubiquitin specific protease 41 0.0009 0.0007 0.001
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0616 0.6257 1
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Echinococcus granulosus ATP binding cassette sub family B 0.0184 0.1812 0.2601
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0026 0.0177 0.0248
Onchocerca volvulus Serine\/threonine kinase homolog 0.0114 0.1086 0.1727
Plasmodium falciparum ABC transporter B family member 5, putative 0.0196 0.1932 0.3082
Schistosoma mansoni tar DNA-binding protein 0.0685 0.6967 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0022 0.0136 0.0189
Trypanosoma brucei ABC transporter, putative 0.0012 0.0031 0.0056
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Schistosoma mansoni smad1 5 8 and 0.0033 0.025 0.0359
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0009 0.0007 0.0007
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1086 0.1727
Trypanosoma cruzi multidrug resistance protein E, putative 0.0196 0.1932 0.4416
Entamoeba histolytica ATP-binding cassette protein, putative 0.0196 0.1932 0.308
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0698 0.1585
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Giardia lamblia ABC transporter family protein 0.0012 0.0031 0.0063
Leishmania major ATP-binding cassette protein subfamily G, member 1, putative 0.0076 0.0698 0.1106
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0009 0.0007 0.001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0284 0.2833 0.4067
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Schistosoma mansoni smad1 5 8 and 0.0033 0.025 0.0359
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0009 0.0007 0.001
Echinococcus granulosus ATP binding cassette sub family G 0.0432 0.4366 0.6267
Brugia malayi mothers against decapentaplegic homolog 3 0.0015 0.0063 0.0084
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0116 0.025
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.0007
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0022 0.0136 0.0207
Brugia malayi serine/threonine-protein kinase plk-2 0.0114 0.1086 0.1554
Schistosoma mansoni ATP-dependent transporter 0.0012 0.0031 0.0045
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0088 0.0185
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0175 0.0252
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0065 0.0578 0.0824
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0175 0.0402
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0116 0.0136
Plasmodium falciparum ABC transporter I family member 1, putative 0.0012 0.0031 0.0042
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0038
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis ABC transporter, putative 0.0616 0.6257 1
Echinococcus granulosus ATP binding cassette sub family B 0.0196 0.1932 0.2773
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0009 0.0007 0.001
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0022 0.0136 0.0189
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0196 0.1932 0.3082
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0196 0.1932 0.2768
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.027 0.0604
Giardia lamblia Kinase, PLK 0.0114 0.1086 0.2551
Schistosoma mansoni ATP-binding cassette transporter 0.0012 0.0031 0.0045
Trichomonas vaginalis abca5, putative 0.0012 0.0031 0.0039
Plasmodium vivax ABC transporter B family member 7, putative 0.0196 0.1932 0.308
Brugia malayi multidrug resistance related protein 1 0.0196 0.1932 0.2768
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0088 0.0133
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0175 0.0175
Echinococcus multilocularis importin subunit beta 1 0.0035 0.027 0.027
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0202 0.0448
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0022 0.0136 0.0196
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0009 0.0007 0.001
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0116 0.025
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0009 0.0007 0.0007
Schistosoma mansoni multidrug resistance protein 0.0196 0.1932 0.2773
Toxoplasma gondii ATP-binding cassette sub-family E member 1, putative 0.0012 0.0031 0.0042
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0032 0.004
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0175 0.0386
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0356 0.3579 0.57
Echinococcus granulosus ATP binding cassette sub family G 0.0432 0.4366 0.6267
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0053 0.0073
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0009 0.0007 0.001
Mycobacterium ulcerans O-antigen/lipopolysaccharide transport integral membrane protein ABC transporter RfbD 0.0065 0.0578 0.1261
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0116 0.0166
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0196 0.1932 0.4384
Treponema pallidum amino acid ABC transporter ATP-binding protein 0.0012 0.0031 0.5
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0009 0.0007 0.001
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0196 0.1932 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0009 0.0007 0.001
Treponema pallidum ABC transporter, ATP-binding protein 0.0012 0.0031 0.5
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0196 0.1932 0.308
Entamoeba histolytica ATP-binding cassette sub-family E member 1, putative 0.0012 0.0031 0.0039
Echinococcus multilocularis serine protein kinase ATM 0.003 0.022 0.022
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0004
Echinococcus multilocularis ATP binding cassette sub family B 0.0196 0.1932 0.1932
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0032 0.004
Schistosoma mansoni ATP-dependent transporter 0.0012 0.0031 0.0045
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0009 0.0007 0.001
Plasmodium falciparum ataxin-2 like protein, putative 0.0132 0.127 0.2024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0611 0.1386
Trypanosoma cruzi ATP-binding cassette protein subfamily G 0.0076 0.0698 0.1585
Echinococcus multilocularis multidrug resistance protein 1 0.0616 0.6257 0.6257
Entamoeba histolytica P-glycoprotein-5 0.0616 0.6257 1
Schistosoma mansoni hypothetical protein 0.0372 0.3741 0.537
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.1086 0.156
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Leishmania major pentamidine resistance protein 1 0.0196 0.1932 0.308
Trypanosoma brucei multidrug resistance protein E 0.0196 0.1932 0.4416
Brugia malayi ABC transporter 0.0196 0.1932 0.2768
Echinococcus multilocularis ubiquitin specific protease 41 0.0009 0.0007 0.0007
Brugia malayi P-glycoprotein 0.0012 0.0031 0.0038
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0009 0.0007 0.0004
Plasmodium falciparum ubiquitin specific protease, putative 0.0009 0.0007 0.0004
Trypanosoma cruzi ribonuclease L inhibitor, putative 0.0012 0.0031 0.0056
Echinococcus multilocularis mothers against decapentaplegic 6 0.0015 0.0063 0.0063
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0616 0.6257 0.8981
Onchocerca volvulus 0.0012 0.0031 0.0039
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0196 0.1932 0.3082
Loa Loa (eye worm) glutaminase 2 0.0281 0.2808 0.4027
Trichomonas vaginalis Phosphonates import ATP-binding protein phnC, putative 0.0012 0.0031 0.0039
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0114 0.1086 0.1086
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0184 0.1812 0.2596
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0009 0.0007 0.0007
Schistosoma mansoni hypothetical protein 0.0098 0.0925 0.1328
Echinococcus granulosus ATP binding cassette sub family F 0.0012 0.0031 0.0045
Loa Loa (eye worm) hypothetical protein 0.0496 0.5024 0.721
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0432 0.4366 1
Loa Loa (eye worm) RIM ABC transporter 0.0012 0.0031 0.0038
Loa Loa (eye worm) RIM ABC transporter 0.0012 0.0031 0.0038
Entamoeba histolytica RNAseL inhibitor-like protein, putative 0.0012 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Schistosoma mansoni hypothetical protein 0.0205 0.2019 0.2899
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0022 0.0136 0.0207
Loa Loa (eye worm) pax transcription factor protein 2 0.0261 0.2597 0.3724
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0196 0.1932 0.308
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0175 0.0273
Leishmania major hypothetical protein, conserved 0.0012 0.0031 0.0039
Leishmania major ATP-binding cassette subfamily A, member 1, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0493 0.0778
Entamoeba histolytica P-glyco protein 6, putative 0.0616 0.6257 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0196 0.1932 0.4384
Loa Loa (eye worm) glutaminase 0.0281 0.2808 0.4027
Trichomonas vaginalis abca8, putative 0.0012 0.0031 0.0039
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.025 0.0353
Giardia lamblia GTOR 0.0022 0.0136 0.031
Leishmania major ATP-binding cassette protein subfamily F, member 1, putative 0.0012 0.0031 0.0039
Brugia malayi MH2 domain containing protein 0.0033 0.025 0.0353
Onchocerca volvulus 0.0012 0.0031 0.0039
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0009 0.0007 0.001
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0005 0.0007
Mycobacterium ulcerans hypothetical protein 0.0065 0.0578 0.1261
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Schistosoma mansoni tar DNA-binding protein 0.0685 0.6967 1
Trypanosoma cruzi ATP-binding cassette transporter ABCA1, putative 0.0012 0.0031 0.0056
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0616 0.6257 1
Plasmodium vivax FeS assembly ATPase SufC, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Echinococcus granulosus ubiquitin specific peptidase c family 0.0009 0.0007 0.001
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0009 0.0007 0.001
Leishmania major ATP-binding cassette protein subfamily A, member 7, putative 0.0012 0.0031 0.0039
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0184 0.1812 0.2601
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0196 0.1932 0.4416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0669 0.096
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0009 0.0007 0.001
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0088 0.0119
Toxoplasma gondii target of rapamycin (TOR), putative 0.0022 0.0136 0.0211
Brugia malayi CXXC zinc finger family protein 0.0035 0.0269 0.0379
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Trypanosoma brucei ABC transporter, putative 0.0012 0.0031 0.0056
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Trichomonas vaginalis abca7, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0616 0.6257 1
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0116 0.016
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0009 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0196 0.1932 0.4416
Schistosoma mansoni fkbp-rapamycin associated protein 0.0012 0.0038 0.0055
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0088 0.0088
Mycobacterium ulcerans antibiotic ABC transporter transmembrane protein 0.0065 0.0578 0.1261
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0196 0.1932 0.4416
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0038
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0012 0.0038 0.0048
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0316 0.0454
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0009 0.0007 0.0004
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0196 0.1932 0.4416
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0031 0.0039
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0088 0.0185
Loa Loa (eye worm) ABC transporter 0.0012 0.0031 0.0038
Echinococcus granulosus bloom syndrome protein 0.0022 0.0137 0.0197
Schistosoma mansoni Smad4 0.0015 0.0063 0.009
Brugia malayi Latrophilin receptor protein 2 0.0098 0.0925 0.1322
Entamoeba histolytica ATP-binding cassette protein, putative 0.0012 0.0031 0.0039
Leishmania major DNA polymerase eta, putative 0.0046 0.0386 0.0606
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0032 0.0058
Entamoeba histolytica P-glycoprotein-2 0.0616 0.6257 1
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0611 0.1386
Trypanosoma cruzi hypothetical protein, conserved 0.0065 0.0578 0.131
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1086 0.1727
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Echinococcus granulosus neuropeptide receptor A26 0.0561 0.5694 0.8173
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0009 0.0007 0.001
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0012 0.0031 0.0056
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.0611 0.0871
Entamoeba histolytica Ran family GTPase 0.0026 0.0175 0.0269
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0009 0.0007 0.001
Schistosoma mansoni hypothetical protein 0.0213 0.2102 0.3017
Echinococcus multilocularis ATP binding cassette sub family G 0.0432 0.4366 0.4366
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0196 0.1932 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0616 0.6257 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0031 0.0038
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0175 0.0245
Treponema pallidum sugar ABC transporter ATP-binding protein 0.0012 0.0031 0.5
Schistosoma mansoni hypothetical protein 0.0059 0.0521 0.0747
Loa Loa (eye worm) hypothetical protein 0.0196 0.1932 0.2768
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.0611 0.1386
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0009 0.0007 0.001
Loa Loa (eye worm) RNA binding protein 0.0685 0.6967 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0116 0.025
Trypanosoma brucei ABC transporter, putative 0.0012 0.0031 0.0056
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0009 0.0007 0.001
Leishmania major p-glycoprotein 0.0616 0.6257 1
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0116 0.025
Loa Loa (eye worm) ATP-binding cassette 0.0012 0.0031 0.0038
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0616 0.6257 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0015 0.0063 0.0084
Loa Loa (eye worm) ABC transporter 0.0196 0.1932 0.2768
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0022 0.0022
Echinococcus multilocularis ATP binding cassette sub family F 0.0012 0.0031 0.0031
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0009 0.0007 0.001
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0088 0.0088
Leishmania major ATP-binding cassette protein subfamily A, member 4, putative 0.0012 0.0031 0.0039
Loa Loa (eye worm) hypothetical protein 0.0098 0.0925 0.1322
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0009 0.0007 0.001
Echinococcus multilocularis ATP binding cassette sub family B 0.0604 0.6137 0.6137
Plasmodium vivax ABC transporter E family member 1, putative 0.0012 0.0031 0.0039
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0009 0.0007 0.001
Trypanosoma cruzi multidrug resistance protein E, putative 0.0012 0.0031 0.0056
Onchocerca volvulus 0.0012 0.0031 0.0039
Echinococcus multilocularis ATP binding cassette sub family B 0.0196 0.1932 0.1932
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Mycobacterium tuberculosis Probable daunorubicin-dim-transport integral membrane protein ABC transporter DrrC 0.0065 0.0578 0.0878
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0116 0.0174
Echinococcus granulosus snurportin 1 0.0372 0.3741 0.537
Leishmania major ATP-binding cassette protein subfamily E, member 1, putative 0.0012 0.0031 0.0039
Trypanosoma cruzi ABC transport system ATP-binding protein, putative 0.0012 0.0031 0.0056
Echinococcus multilocularis ATP binding cassette sub family G 0.0432 0.4366 0.4366
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0004
Entamoeba histolytica ATP-binding cassette, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0616 0.6257 1
Trypanosoma brucei ATP-binding cassette sub-family F member 1, putative 0.0012 0.0031 0.0056
Echinococcus multilocularis expressed protein 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0009 0.0007 0.001
Trypanosoma brucei DNA polymerase eta, putative 0.0046 0.0386 0.0869
Mycobacterium leprae Probable lipopolysaccharide transport integral membrane ABC transporter RfbD 0.0065 0.0578 0.2877
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0616 0.6257 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0004
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0009 0.0007 0.001
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0005 0.0005
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0202 0.0312
Brugia malayi 6-phosphofructokinase 0.0012 0.0031 0.0038
Trichomonas vaginalis abca8, putative 0.0012 0.0031 0.0039
Loa Loa (eye worm) P-glycoprotein 0.0012 0.0031 0.0038
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.003 0.022 0.049
Trypanosoma brucei ABC transporter, putative 0.0012 0.0031 0.0056
Plasmodium vivax ABC transporter F family member 2, putative 0.0012 0.0031 0.0039
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0116 0.0166
Trichomonas vaginalis abca1, putative 0.0012 0.0031 0.0039
Schistosoma mansoni cpg binding protein 0.0037 0.0289 0.0415
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0038 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0038 0.005
Giardia lamblia ABC transporter, ATP-binding protein 0.0012 0.0031 0.0063
Brugia malayi isocitrate dehydrogenase 0.0017 0.0088 0.0119
Leishmania major ATP-binding cassette protein subfamily D, member 3, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Trypanosoma cruzi glycosomal transporter (GAT1), putative 0.0012 0.0031 0.0056
Giardia lamblia ABC transporter family protein 0.0012 0.0031 0.0063
Giardia lamblia ABC transporter, ATP-binding protein 0.0012 0.0031 0.0063
Echinococcus granulosus importin subunit beta 1 0.0035 0.027 0.0388
Entamoeba histolytica ATP-binding cassette, sub-family C, putative 0.0012 0.0031 0.0039
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Plasmodium vivax multidrug resistance protein 1, putative 0.0616 0.6257 1
Loa Loa (eye worm) Smad1 0.0033 0.025 0.0353
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0009 0.0007 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Plasmodium falciparum importin beta, putative 0.0035 0.027 0.0424
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0026 0.0177 0.039
Schistosoma mansoni ABC transporter 0.0065 0.0578 0.083
Leishmania major phosphatidylinositol 3-kinase, putative 0.0022 0.0136 0.0207
Echinococcus multilocularis ATP binding cassette sub family F 0.0012 0.0031 0.0031
Toxoplasma gondii ABC transporter, putative 0.0196 0.1932 0.3082
Echinococcus multilocularis neuropeptide receptor A26 0.0561 0.5694 0.5694
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0003
Leishmania major hypothetical protein, conserved 0.0012 0.0031 0.0039
Trichomonas vaginalis abca1, putative 0.0012 0.0031 0.0039
Mycobacterium ulcerans daunorubicin-DIM-transport integral membrane protein ABC transporter DrrB 0.0065 0.0578 0.1261
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0616 0.6257 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0616 0.6257 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.0611 0.0877
Leishmania major ATP-binding cassette protein subfamily H, member 2, putative 0.0012 0.0031 0.0039
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0616 0.6257 1
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Leishmania major DNA polymerase eta, putative 0.0032 0.0245 0.038
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0022 0.0136 0.0297
Giardia lamblia ABC transporter family protein 0.0012 0.0031 0.0063
Echinococcus granulosus multidrug resistance protein 1 0.0616 0.6257 0.8981
Treponema pallidum ABC transporter, ATP-binding protein 0.0012 0.0031 0.5
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0196 0.1932 0.308
Plasmodium falciparum ABC transporter E family member 1, putative 0.0012 0.0031 0.0042
Giardia lamblia ABC transporter family protein 0.0012 0.0031 0.0063
Loa Loa (eye worm) hypothetical protein 0.0196 0.1932 0.2768
Trypanosoma cruzi PAB1-binding protein , putative 0.0132 0.127 0.2898
Brugia malayi ABC transporter transmembrane region family protein 0.0196 0.1932 0.2768
Schistosoma mansoni ATP-dependent transporter 0.0012 0.0031 0.0045
Echinococcus granulosus multidrug resistance protein 1 0.0431 0.4356 0.6253
Echinococcus multilocularis GPCR, family 2 0.0098 0.0925 0.0925
Brugia malayi ImpB/MucB/SamB family protein 0.0046 0.0386 0.0547
Echinococcus multilocularis ATP binding cassette sub family B 0.0196 0.1932 0.1932
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0188 0.1852 0.2659
Echinococcus granulosus multidrug resistance associated protein 1 0.0196 0.1932 0.2773
Loa Loa (eye worm) ATP-binding cassette subfamily E 0.0012 0.0031 0.0038
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0196 0.1932 0.308
Schistosoma mansoni multidrug resistance protein 0.0012 0.0031 0.0045
Echinococcus multilocularis ATP binding cassette sub family G 0.0432 0.4366 0.4366
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0088 0.0129
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0432 0.4366 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0578 0.0824
Trichomonas vaginalis abca6, putative 0.0012 0.0031 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0116 0.025
Trichomonas vaginalis abca9, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0009 0.0004
Echinococcus multilocularis multidrug resistance protein 1 0.0616 0.6257 0.6257
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0616 0.6257 0.6257
Brugia malayi ABC transporter transmembrane region family protein 0.0184 0.1812 0.2596
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0009 0.0007 0.0004
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Echinococcus granulosus cpg binding protein 0.0037 0.0289 0.0415
Schistosoma mansoni calpain-7 (C02 family) 0.0009 0.0007 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0009 0.0007 0.0005
Brugia malayi TAR-binding protein 0.0685 0.6967 1
Brugia malayi hypothetical protein 0.0085 0.0789 0.1126
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0009 0.0007 0.0003
Treponema pallidum ABC transporter, ATP-binding protein (troB) 0.0012 0.0031 0.5
Trypanosoma cruzi target of rapamycin kinase 3 0.0022 0.0136 0.0297
Loa Loa (eye worm) MH2 domain-containing protein 0.0483 0.4888 0.7014
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.027 0.0604
Schistosoma mansoni smad 0.0015 0.0063 0.009
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0022 0.0136 0.0196
Schistosoma mansoni smdr2 0.0616 0.6257 0.8981
Treponema pallidum ABC transporter, ATP-binding protein 0.0012 0.0031 0.5
Entamoeba histolytica P-glycoprotein 5, putative 0.0012 0.0031 0.0039
Trypanosoma cruzi ABC transporter, putative 0.0012 0.0031 0.0056
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0009 0.0007 0.001
Plasmodium falciparum CCR4-associated factor 16, putative 0.0012 0.0031 0.0042
Treponema pallidum ABC transporter, ATP-binding protein 0.0012 0.0031 0.5
Treponema pallidum cobalt ABC transporter, ATP-binding protein 0.0012 0.0031 0.5
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0009 0.0007 0.0003
Toxoplasma gondii ABC transporter, ATP-binding domain-containing protein 0.0012 0.0031 0.0042
Trypanosoma brucei ABC transport system ATP-binding protein, putative 0.0012 0.0031 0.0056
Leishmania major importin beta-1 subunit, putative 0.0028 0.0202 0.0312
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0009 0.0007 0.001
Trypanosoma brucei ABC transporter, putative 0.0012 0.0031 0.0056
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0116 0.025
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0009 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0003
Trichomonas vaginalis ATP binding cassete (ABC) transporter, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0616 0.6257 1
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0009 0.0007 0.0003
Onchocerca volvulus 0.0035 0.0269 0.0419
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0012 0.0031 0.0045
Echinococcus granulosus ATP binding cassette sub family B 0.0196 0.1932 0.2773
Trichomonas vaginalis PIKK family atypical protein kinase 0.0022 0.0136 0.0207
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0022 0.0136 0.0196
Trypanosoma brucei polo-like protein kinase 0.0114 0.1086 0.2477
Loa Loa (eye worm) transcription factor SMAD2 0.0483 0.4888 0.7014
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0196 0.1932 0.3082
Loa Loa (eye worm) hypothetical protein 0.0604 0.6137 0.8808
Mycobacterium ulcerans daunorubicin-DIM-transport integral membrane protein ABC transporter DrrC 0.0065 0.0578 0.1261
Plasmodium falciparum ABC transporter G family member 2 0.0432 0.4366 0.6976
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0031 0.0056
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0009 0.0007 0.0004
Schistosoma mansoni smad1 5 8 and 0.0033 0.025 0.0359
Schistosoma mansoni importin beta-1 0.0035 0.027 0.0388
Echinococcus multilocularis snurportin 1 0.0372 0.3741 0.3741
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0062 0.0092
Giardia lamblia Multidrug resistance ABC transporter ATP-binding and permease protein 0.0012 0.0031 0.0063
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.003 0.022 0.049
Loa Loa (eye worm) ATP-binding cassette 0.0012 0.0031 0.0038
Leishmania major ATP-binding cassette protein subfamily A, member 10, putative,ABC transporter, putative 0.0012 0.0031 0.0039
Giardia lamblia ABC transporter family protein 0.0012 0.0031 0.0063
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0009 0.0007 0.0007
Schistosoma mansoni multidrug resistance protein 0.0616 0.6257 0.8981
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0005 0.000000000068003
Plasmodium vivax multidrug resistance protein 2, putative 0.0196 0.1932 0.308
Entamoeba histolytica ABC transporter, putative 0.0012 0.0031 0.0039
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0616 0.6257 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0188 0.1852 0.2654
Echinococcus multilocularis dna polymerase kappa 0.002 0.0116 0.0116
Schistosoma mansoni smdr1 0.0196 0.1932 0.2773
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0007
Plasmodium falciparum ABC transporter B family member 6, putative 0.0196 0.1932 0.3082
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0698 0.1585
Onchocerca volvulus 0.0616 0.6257 1
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0616 0.6257 0.898
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0005 0.0007
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.025 0.025
Schistosoma mansoni tar DNA-binding protein 0.0685 0.6967 1
Entamoeba histolytica ATP-binding cassette sub-family E member 1, putative 0.0012 0.0031 0.0039
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0196 0.1932 0.3053
Loa Loa (eye worm) hypothetical protein 0.0213 0.2102 0.3013
Trypanosoma brucei ABC transporter, putative 0.0012 0.0031 0.0056
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0432 0.4366 0.6975
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0022 0.0136 0.0297
Toxoplasma gondii FATC domain-containing protein 0.003 0.022 0.0345
Brugia malayi FAT domain containing protein 0.001 0.0009 0.0007
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0496 0.5024 0.721
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0269 0.0379
Plasmodium vivax ABC transporter B family member 5, putative 0.0196 0.1932 0.308
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0009 0.0007 0.0004
Trichomonas vaginalis ABC transporter, putative 0.0012 0.0031 0.0039

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 6.02 uM PUBCHEM_BIOASSAY: Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex. (Class of assay: confirmatory) ChEMBL. No reference
IC50 (functional) = 3.101923 uM PUBCHEM_BIOASSAY: Image-Based HTS for Selective Antagonists of GPR35. High content imaging assay of the inhibition of receptor-mediated beta-arrestin GFP translocation to cytosolic compartments Secondary Screen (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2079, AID2397, AID2480, AID463201, AID463202, AID463217, AID463227, AID463228, AID488987] ChEMBL. No reference
Potency (functional) 0.2592 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 2.0667 uM PUBCHEM_BIOASSAY: qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia: Secondary assay (no NCS) hit validation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485356] ChEMBL. No reference
Potency (functional) 3.1623 uM PubChem BioAssay. qHTS for Inhibitors of Vif-A3G Interactions: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.4411 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3G interactions: Cherry picks counterscreen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 8.9125 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of binding or entry into cells for Lassa Virus. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463114, AID540249] ChEMBL. No reference
Potency (functional) 12.5168 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3F interactions: Cherry picks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Antagonists of the Neuropeptide S Receptor: cAMP Signal Transduction. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of RanGTP induced Rango (Ran-regulated importin-beta cargo) - Importin beta complex dissociation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540262] ChEMBL. No reference
Potency (functional) = 14.1254 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) 15.7578 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3G interactions: Cherry picks. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 16.3601 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 17.6805 uM PubChem BioAssay. qHTS for inhibitors of Vif-A3F interactions: Cherry picks counterscreen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 17.7828 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.3564 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.8876 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 42.5615 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Rango (Ran-regulated importin-beta cargo) - Importin beta complex formation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID540273] ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID485342, AID485388] ChEMBL. No reference
Potency (functional) 63.0957 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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