Detailed information for compound 1397735

Basic information

Technical information
  • TDR Targets ID: 1397735
  • Name: 5,6,7-trimethoxy-4-[4-(4-methylphenyl)phenyl] chromen-2-one
  • MW: 402.439 | Formula: C25H22O5
  • H donors: 0 H acceptors: 1 LogP: 4.99 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1c(OC)c(OC)cc2c1c(cc(=O)o2)c1ccc(cc1)c1ccc(cc1)C
  • InChi: 1S/C25H22O5/c1-15-5-7-16(8-6-15)17-9-11-18(12-10-17)19-13-22(26)30-20-14-21(27-2)24(28-3)25(29-4)23(19)20/h5-14H,1-4H3
  • InChiKey: GAUDGAGNQFFNCB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5,6,7-trimethoxy-4-[4-(4-methylphenyl)phenyl]-2-chromenone
  • 5,6,7-trimethoxy-4-[4-(4-methylphenyl)phenyl]coumarin
  • KUC100455N
  • NCGC00159812-01
  • KUCT2B37C37D37F33

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Equus caballus Ferritin light chain Starlite/ChEMBL No references
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 44.4 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 142 aa 29.6 %
Echinococcus multilocularis expressed protein Ferritin light chain   175 aa 146 aa 30.1 %
Schistosoma mansoni ferritin Ferritin light chain   175 aa 171 aa 43.9 %
Echinococcus granulosus expressed protein Ferritin light chain   175 aa 146 aa 28.8 %
Schistosoma japonicum Ferritin, putative Ferritin light chain   175 aa 144 aa 24.3 %
Schistosoma mansoni apoferritin-2 Ferritin light chain   175 aa 146 aa 28.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica protein kinase , putative 0.0062 0.0087 0.2473
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0614 0.5338
Echinococcus granulosus biogenic amine 5HT receptor 0.0023 0.0005 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.0095 0.0157 0.1338
Leishmania major alpha glucosidase II subunit, putative 0.0142 0.0256 0.6032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0005 0.0001
Echinococcus granulosus transcription factor btf3 0.0034 0.0027 0.0055
Brugia malayi Protein kinase domain containing protein 0.0172 0.0319 0.161
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0081 0.0128 0.0124
Echinococcus granulosus histone acetyltransferase KAT2B 0.0149 0.027 0.0623
Loa Loa (eye worm) hypothetical protein 0.0045 0.0051 0.0261
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0614 0.5338
Trypanosoma cruzi hypothetical protein, conserved 0.0186 0.0348 0.8234
Echinococcus granulosus fmrfamide receptor 0.0023 0.0005 0.0003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Loa Loa (eye worm) hypothetical protein 0.0133 0.0236 0.1207
Echinococcus granulosus beta LACTamase domain containing family member 0.0186 0.0348 0.0807
Schistosoma mansoni serine/threonine protein kinase 0.0043 0.0046 0.0109
Loa Loa (eye worm) acetyltransferase 0.0155 0.0284 0.1453
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0312 0.0614 0.3146
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.01 0.0166 0.0434
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0118 0.0998
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0541
Trypanosoma brucei SLACS retrotransposable element (part), putative 0.0041 0.0042 0.0101
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Echinococcus multilocularis lysosomal alpha glucosidase 0.064 0.1308 0.1305
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.0162 0.0298 0.1528
Echinococcus granulosus Smad4 0.0057 0.0077 0.0172
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0043 0.0221
Schistosoma mansoni Smad4 0.0026 0.001 0.0023
Brugia malayi hypothetical protein 0.0041 0.0042 0.0188
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Loa Loa (eye worm) Smad1 0.0057 0.0077 0.0395
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0053 0.0068 0.0064
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0057 0.0077 0.0073
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0074 0.0113 0.2613
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0008 0.001
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0057 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0005 0.0001
Echinococcus multilocularis survival motor neuron protein 1 0.0718 0.1473 0.1469
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0068 0.01 0.2296
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0068 0.1898
Echinococcus multilocularis allatostatin A receptor 0.0023 0.0005 0.0001
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0005 0.0003
Schistosoma mansoni hypothetical protein 0.0041 0.0042 0.0098
Trypanosoma brucei unspecified product 0.0026 0.0012 0.002
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0079 0.0123 0.0628
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0028 0.0015 0.028
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0067 0.0097 0.0093
Echinococcus granulosus RUN 0.0341 0.0676 0.1578
Echinococcus multilocularis lamin dm0 0.0079 0.0123 0.0119
Echinococcus multilocularis aurora kinase A 0.0062 0.0087 0.0083
Schistosoma mansoni lipoxygenase 0.2041 0.4267 1
Leishmania major hypothetical protein, conserved 0.01 0.0166 0.3891
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0028 0.0015 0.0016
Plasmodium falciparum plasmepsin IX 0.0068 0.01 0.1405
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Toxoplasma gondii pyruvate carboxylase 0.0064 0.0091 0.2087
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0037 0.0088
Plasmodium falciparum LCCL domain-containing protein 0.0341 0.0676 1
Loa Loa (eye worm) nuclear factor I 0.0032 0.0023 0.0117
Echinococcus multilocularis tumor protein p63 0.0343 0.0681 0.0677
Schistosoma mansoni alpha glucosidase 0.0142 0.0256 0.0599
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0022 0.0049
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0037 0.0785
Onchocerca volvulus Telomerase reverse transcriptase homolog 0.0041 0.0042 0.0361
Echinococcus multilocularis g-protein coupled receptor 0.0023 0.0005 0.0001
Brugia malayi hypothetical protein 0.0292 0.0573 0.2918
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0087 0.0083
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0118 0.1672
Schistosoma mansoni amine GPCR 0.0023 0.0005 0.0012
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0077 0.0118 0.0114
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0023 0.0005 0.0026
Trichomonas vaginalis reverse transcriptase [C. elegans], putative 0.0041 0.0042 0.0303
Echinococcus granulosus somatostatin receptor 0.0023 0.0005 0.0003
Giardia lamblia Kinase, CMGC GSK 0.0053 0.0068 0.1271
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0005 0.0003
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0002 0.0008
Brugia malayi RNA, U transporter 1 0.0089 0.0145 0.0716
Loa Loa (eye worm) hypothetical protein 0.0038 0.0037 0.0188
Loa Loa (eye worm) doublecortin family protein 0.0341 0.0676 0.3464
Echinococcus granulosus ubiquitin specific protease 41 0.0077 0.0118 0.0267
Echinococcus granulosus hypothetical protein 0.0023 0.0005 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0005 0.0012
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0024 0.002
Brugia malayi cytoplasmic intermediate filament protein 0.0042 0.0045 0.0206
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0077 0.0118 0.0578
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0179 0.0334 0.033
Plasmodium vivax aspartyl protease, putative 0.0068 0.01 0.1405
Echinococcus granulosus lipoxygenase domain containing protein 0.0341 0.0676 0.1578
Toxoplasma gondii aspartyl protease ASP3 0.0068 0.01 0.2296
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.022 0.0515
Brugia malayi hypothetical protein 0.0341 0.0676 0.3447
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0005 0.0001
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0186 0.0348 0.1781
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0023 0.0005 0.0012
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0028 0.0015 0.0095
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0029 0.0148
Brugia malayi Pre-SET motif family protein 0.0064 0.0091 0.0443
Schistosoma mansoni importin beta-1 0.0031 0.0022 0.0052
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0024 0.0007 0.0009
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0033 0.0029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0453 0.0913 0.2132
Plasmodium falciparum plasmepsin III 0.0068 0.01 0.1405
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0005 0.0003
Echinococcus multilocularis Polycystic kidney disease protein 0.0341 0.0676 0.0673
Mycobacterium tuberculosis Probable esterase LipL 0.0186 0.0348 0.0499
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0015 0.0259
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0037 0.0088
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0076 0.0116 0.0272
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0024 0.0485
Schistosoma mansoni hypothetical protein 0.0341 0.0676 0.1585
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0077 0.0118 0.2722
Echinococcus granulosus KRAB A domain containing protein 0.0041 0.0042 0.0089
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0023 0.0005 0.0026
Schistosoma mansoni smad 0.0026 0.001 0.0023
Trypanosoma brucei RNA helicase, putative 0.1796 0.3749 1
Loa Loa (eye worm) hypothetical protein 0.0077 0.0118 0.0603
Echinococcus granulosus g protein coupled receptor 0.0023 0.0005 0.0003
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0055 0.0071 0.0158
Onchocerca volvulus Glucosylceramidase homolog 0.0205 0.0388 0.3773
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0023 0.0005 0.0003
Treponema pallidum ribonuclease H (rnhA) 0.022 0.0421 0.5611
Toxoplasma gondii Erv1 / Alr family protein 0.01 0.0166 0.3891
Brugia malayi Doublecortin family protein 0.0341 0.0676 0.3447
Echinococcus granulosus neuropeptide FF receptor 2 0.0023 0.0005 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0388 0.3347
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0015 0.005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Mycobacterium ulcerans replicative DNA helicase DnaB 0.0375 0.0747 0.6512
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0015 0.0259
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0068 0.1536
Entamoeba histolytica transcription factor BTF3, putative 0.0034 0.0027 0.0661
Entamoeba histolytica hypothetical protein 0.0024 0.0007 0.0051
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0042 0.0905
Echinococcus granulosus geminin 0.069 0.1413 0.3306
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0024 0.0123
Toxoplasma gondii aurora kinase 0.0062 0.0087 0.1982
Entamoeba histolytica hypothetical protein 0.0179 0.0334 1
Mycobacterium tuberculosis Probable hydrolase 0.0186 0.0348 0.0499
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0041 0.0042 0.0626
Echinococcus multilocularis serotonin receptor 0.0534 0.1085 0.1081
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0146 0.0265 0.1335
Schistosoma mansoni cathepsin D (A01 family) 0.0068 0.01 0.0234
Echinococcus granulosus ribonuclease H1 0.022 0.0421 0.098
Schistosoma mansoni opsin-like receptor 0.0023 0.0005 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0614 0.5338
Loa Loa (eye worm) hypothetical protein 0.0186 0.0348 0.1781
Trichomonas vaginalis ap endonuclease, putative 0.0074 0.0113 0.093
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Echinococcus multilocularis rho associated protein kinase 0.0157 0.0288 0.0284
Echinococcus granulosus L aminoadipate semialdehyde 0.0084 0.0133 0.0302
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0005 0.0003
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0453 0.0913 0.2139
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0176
Schistosoma mansoni polycystin 1-related 0.0341 0.0676 0.1585
Schistosoma mansoni cathepsin D (A01 family) 0.0068 0.01 0.0234
Brugia malayi AMP-binding enzyme family protein 0.0095 0.0157 0.0778
Plasmodium falciparum acyl-CoA synthetase 0.0071 0.0106 0.1494
Trichomonas vaginalis alpha-glucosidase, putative 0.0053 0.0067 0.053
Loa Loa (eye worm) oxidoreductase 0.0028 0.0015 0.0075
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0012 0.009
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0068 0.0064
Echinococcus granulosus histone lysine methyltransferase setb 0.0081 0.0128 0.0291
Schistosoma mansoni hypothetical protein 0.0113 0.0195 0.0456
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0023 0.0005 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0005 0.0001
Loa Loa (eye worm) glutaminase 0.0563 0.1145 0.5862
Loa Loa (eye worm) hypothetical protein 0.0095 0.0157 0.0801
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0095 0.0157 0.0222
Mycobacterium leprae Probable lipase LipE 0.0186 0.0348 0.1505
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.017
Echinococcus granulosus tar DNA binding protein 0.0062 0.0087 0.0195
Plasmodium falciparum basic transcription factor 3b, putative 0.0034 0.0027 0.0323
Loa Loa (eye worm) melatonin receptor type 1A 0.0023 0.0005 0.0026
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0113 0.0195 0.0191
Schistosoma mansoni neuropeptide receptor 0.0023 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Trypanosoma brucei Endonuclease-reverse transcriptase/Reverse transcriptase (RNA-dependent DNA polymerase), putative 0.0041 0.0042 0.0101
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0005 0.0001
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0085 0.019
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0068 0.01 0.2296
Brugia malayi hypothetical protein 0.0149 0.0271 0.1365
Trypanosoma cruzi DNA repair protein, putative 0.0032 0.0024 0.0476
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0068 0.01 0.0096
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0095 0.0157 0.0668
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0064 0.0091 0.0126
Brugia malayi MH2 domain containing protein 0.0026 0.001 0.0026
Plasmodium vivax glycogen synthase kinase 3, putative 0.0053 0.0068 0.0928
Trypanosoma cruzi acetyl-CoA carboxylase 0.0104 0.0176 0.4112
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0057 0.0515
Toxoplasma gondii hypothetical protein 0.0026 0.0012 0.0184
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0068 0.0533
Plasmodium vivax multidomain scavenger receptor, putative 0.0341 0.0676 1
Brugia malayi serine/threonine protein kinase 6 0.0062 0.0087 0.0419
Loa Loa (eye worm) ICD-1 protein 0.0034 0.0027 0.0139
Schistosoma mansoni memapsin-2 (A01 family) 0.0883 0.1821 0.4267
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0022 0.0438
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0087 0.0698
Mycobacterium ulcerans acetyl-CoA synthetase 0.0028 0.0015 0.0095
Wolbachia endosymbiont of Brugia malayi replicative DNA helicase 0.0375 0.0747 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0005 0.0012
Loa Loa (eye worm) DnaJ domain-containing protein 0.0059 0.0081 0.0414
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0024 0.0054
Onchocerca volvulus 0.0157 0.0288 0.2788
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0024 0.0485
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1186 0.246 0.3565
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0064 0.0091 0.2087
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0095 0.0157 0.0222
Echinococcus multilocularis sex peptide receptor 0.0023 0.0005 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0015 0.0095
Echinococcus multilocularis mothers against decapentaplegic 5 0.0057 0.0077 0.0073
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0028 0.0015 0.0047
Toxoplasma gondii exonuclease III APE 0.0074 0.0113 0.2613
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0176
Echinococcus multilocularis ubiquitin specific protease 41 0.0077 0.0118 0.0114
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0062 0.0136
Echinococcus granulosus 7TM GPCR rhodopsin 0.0023 0.0005 0.0003
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0057 0.0134
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0005 0.0001
Leishmania major DNA polymerase eta, putative 0.0038 0.0037 0.0785
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0095 0.0157 0.1338
Brugia malayi Pre-SET motif family protein 0.0443 0.0891 0.4548
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0028 0.0015 0.0259
Echinococcus granulosus orexin receptor type 2 0.0023 0.0005 0.0003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0128 0.03
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0005 0.0003
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0023 0.0005 0.0001
Schistosoma mansoni neuropeptide receptor 0.0023 0.0005 0.0012
Toxoplasma gondii propionate-CoA ligase 0.0028 0.0015 0.0259
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0005 0.0001
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0068 0.01 0.0814
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0015 0.0259
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0043 0.0092
Toxoplasma gondii FATC domain-containing protein 0.0024 0.0007 0.008
Echinococcus multilocularis mothers against decapentaplegic 2 0.0026 0.001 0.0006
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0028 0.0015 0.0025
Echinococcus granulosus neuropeptide receptor A26 0.0487 0.0984 0.23
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0055 0.0071 0.0067
Echinococcus multilocularis muscleblind protein 1 0.0309 0.0608 0.0604
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0053 0.0067 0.053
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0614 0.5338
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0053 0.0068 0.0159
Echinococcus granulosus neuropeptide Y receptor 0.0023 0.0005 0.0003
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0041 0.0042 0.0038
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0084 0.0133 0.0656
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0453 0.0913 0.0909
Trichomonas vaginalis set domain proteins, putative 0.0504 0.102 0.8902
Trypanosoma brucei protein kinase, putative 0.0053 0.0068 0.0171
Brugia malayi MH2 domain containing protein 0.0844 0.1738 0.8894
Schistosoma mansoni cpg binding protein 0.0039 0.0037 0.0087
Leishmania major 4-coumarate:coa ligase-like protein 0.0095 0.0157 0.3656
Plasmodium falciparum glycogen synthase kinase 3 0.0053 0.0068 0.0928
Echinococcus multilocularis somatostatin receptor 0.0023 0.0005 0.0001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0067 0.0098 0.0136
Loa Loa (eye worm) hypothetical protein 0.0079 0.0123 0.0628
Echinococcus granulosus neuropeptide receptor 0.0023 0.0005 0.0003
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0074 0.0113 0.2386
Mycobacterium ulcerans acyl-CoA synthetase 0.0095 0.0157 0.1338
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0118 0.097
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.0005 0.004
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0008 0.0019
Plasmodium falciparum plasmepsin V 0.0068 0.01 0.1405
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0024 0.0485
Loa Loa (eye worm) TYRA-2 protein 0.0023 0.0005 0.0026
Schistosoma mansoni rab6-interacting 0.0341 0.0676 0.1585
Echinococcus multilocularis beta LACTamase domain containing family member 0.0186 0.0348 0.0344
Schistosoma mansoni opsin-like receptor 0.0023 0.0005 0.0012
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0068 0.015
Loa Loa (eye worm) hypothetical protein 0.0718 0.1473 0.754
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Echinococcus granulosus RNA directed DNA polymerase 0.0041 0.0042 0.0089
Schistosoma mansoni myosin xvIII 0.0023 0.0005 0.0012
Echinococcus granulosus dna polymerase eta 0.0038 0.0037 0.0077
Echinococcus granulosus intermediate filament protein 0.0079 0.0123 0.0278
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.0091 0.0087
Trichomonas vaginalis bromodomain-containing protein, putative 0.0047 0.0056 0.0427
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0037 0.0088
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0068 0.1536
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0053 0.0068 0.0347
Onchocerca volvulus 0.0068 0.01 0.0934
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0041 0.0042 0.0038
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0077 0.0118 0.0304
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0041 0.0042 0.0626
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0005 0.0003
Onchocerca volvulus 0.0041 0.0042 0.0361
Loa Loa (eye worm) hypothetical protein 0.0041 0.0043 0.0221
Echinococcus multilocularis G protein coupled receptor 139 0.0023 0.0005 0.0001
Entamoeba histolytica protein kinase, putative 0.0062 0.0087 0.2473
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0005 0.0001
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0028 0.0015 0.005
Trypanosoma cruzi PAB1-binding protein , putative 0.0149 0.0271 0.6396
Mycobacterium tuberculosis Conserved protein 0.0186 0.0348 0.0499
Schistosoma mansoni biogenic amine receptor 0.0023 0.0005 0.0012
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0023 0.0005 0.0001
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0041 0.0042 0.0089
Schistosoma mansoni amine GPCR 0.0023 0.0005 0.0012
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0074 0.0113 0.2613
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0067 0.0098 0.0136
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0068 0.01 0.0234
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0068 0.0159
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0015 0.0075
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.022 0.5172
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0028 0.0015 0.0011
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0028 0.0015 0.0016
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0186 0.0348 0.0815
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Brugia malayi latrophilin 2 splice variant baaae 0.0244 0.0472 0.2396
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0005 0.0003
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0074 0.0113 0.3276
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0336 0.0665 0.3403
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0037 0.0088
Onchocerca volvulus 0.0095 0.0157 0.1493
Leishmania major hypothetical protein, conserved 0.0149 0.0271 0.6396
Brugia malayi Zinc knuckle family protein 0.0041 0.0042 0.0188
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0064 0.0091 0.0764
Brugia malayi MH2 domain containing protein 0.0057 0.0077 0.037
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0028 0.0015 0.0075
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0068 0.0535
Toxoplasma gondii aspartyl protease 0.0068 0.01 0.2296
Schistosoma mansoni zinc finger protein 0.0026 0.001 0.0023
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0064 0.0091 0.2087
Loa Loa (eye worm) hypothetical protein 0.0186 0.0348 0.1781
Entamoeba histolytica protein kinase, putative 0.0062 0.0087 0.2473
Schistosoma mansoni alpha-1 adrenergic receptor 0.0023 0.0005 0.0012
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0074 0.0113 0.1469
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0118 0.1533
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0541
Loa Loa (eye worm) hypothetical protein 0.0048 0.0057 0.0293
Brugia malayi hypothetical protein 0.0179 0.0334 0.1687
Echinococcus multilocularis dna polymerase eta 0.0038 0.0037 0.0033
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0024 0.0007 0.0011
Mycobacterium leprae RECA PROTEIN (RECOMBINASE A) [CONTAINS: Mle RECA INTEIN]. 0.0105 0.0177 0.0756
Brugia malayi hypothetical protein 0.0041 0.0042 0.0188
Echinococcus granulosus Polycystic kidney disease protein 0.0341 0.0676 0.1578
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0614 0.5338
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0005 0.0001
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0005 0.0001
Echinococcus multilocularis neutral alpha glucosidase AB 0.0142 0.0256 0.0252
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0005 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0005 0.0003
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0012 0.0034
Giardia lamblia Ribonuclease H 0.022 0.0421 1
Toxoplasma gondii NAC domain-containing protein 0.0034 0.0027 0.0559
Entamoeba histolytica hypothetical protein 0.0034 0.0027 0.0661
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0043 0.0092
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0024 0.0485
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0023 0.0005 0.0012
Chlamydia trachomatis biotin carboxylase 0.0058 0.0079 0.1005
Brugia malayi Glycosyl hydrolases family 31 protein 0.064 0.1308 0.6688
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0037 0.0259
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0023 0.0005 0.0003
Echinococcus granulosus GPCR family 2 0.0113 0.0195 0.0447
Mycobacterium ulcerans esterase/lipase LipP 0.0186 0.0348 0.3014
Brugia malayi RNase H family protein 0.022 0.0421 0.2138
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0041 0.0042 0.0038
Trichomonas vaginalis D-aminoacylase, putative 0.0186 0.0348 0.2993
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0186 0.0348 0.1759
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0204 0.0388 0.0384
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0028 0.0015 0.0029
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0024 0.002
Trichomonas vaginalis alpha-glucosidase, putative 0.0053 0.0067 0.053
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0005 0.0014
Schistosoma mansoni biogenic amine (5HT) receptor 0.0023 0.0005 0.0012
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0062 0.0084
Loa Loa (eye worm) glutaminase 2 0.0563 0.1145 0.5862
Brugia malayi hypothetical protein 0.0096 0.0159 0.0792
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.01 0.0166 0.2397
Echinococcus granulosus tumor protein p63 0.0343 0.0681 0.1588
Entamoeba histolytica hypothetical protein 0.0025 0.001 0.0124
Echinococcus multilocularis muscleblind protein 0.0309 0.0608 0.0604
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.022 0.1893
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0056 0.0122
Echinococcus granulosus dnaJ subfamily B 0.0494 0.0999 0.2334
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0012 0.0081
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0028 0.0015 0.0259
Brugia malayi MAP kinase sur-1 0.0053 0.0068 0.0323
Loa Loa (eye worm) aspartyl protease 6 0.0068 0.01 0.0511
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Brugia malayi CXXC zinc finger family protein 0.0035 0.0029 0.0123
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0005 0.0003
Schistosoma mansoni Smad4 0.0026 0.001 0.0023
Plasmodium vivax acetyl-CoA synthetase, putative 0.0028 0.0015 0.0137
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Schistosoma mansoni hypothetical protein 0.0023 0.0005 0.0012
Echinococcus multilocularis protein kinase shaggy 0.0053 0.0068 0.0064
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0084 0.0133 0.0311
Schistosoma mansoni hypothetical protein 0.0067 0.0097 0.0228
Echinococcus granulosus arachidonate 5 lipoxygenase 0.2041 0.4267 1
Brugia malayi RNase H family protein 0.022 0.0421 0.2138
Schistosoma mansoni alpha-glucosidase 0.0551 0.112 0.2624
Onchocerca volvulus 0.0155 0.0283 0.2741
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0053 0.0067 0.1524
Plasmodium vivax plasmepsin IV, putative 0.0068 0.01 0.1405
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0005 0.0003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0023 0.0005 0.0003
Trypanosoma cruzi DNA repair protein, putative 0.0032 0.0024 0.0476
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0118 0.1672
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0077 0.0118 0.097
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0037 0.0088
Brugia malayi beta-lactamase 0.0186 0.0348 0.1759
Plasmodium vivax aspartyl proteinase, putative 0.0068 0.01 0.1405
Schistosoma mansoni phosphoglucomutase 0.022 0.0421 0.0988
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.0128 0.03
Brugia malayi intracellular kinase 0.0053 0.0068 0.0322
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0068 0.1536
Schistosoma mansoni ap endonuclease 0.0074 0.0113 0.0265
Echinococcus multilocularis protein patched 0.0041 0.0043 0.0039
Echinococcus multilocularis expressed conserved protein 0.0091 0.0147 0.0144
Schistosoma mansoni serine/threonine protein kinase 0.0157 0.0288 0.0675
Trypanosoma brucei transcription factor BTF3, putative 0.0034 0.0027 0.0062
Echinococcus multilocularis mothers against decapentaplegic 6 0.0026 0.001 0.0006
Loa Loa (eye worm) RNA binding protein 0.0062 0.0087 0.0445
Plasmodium falciparum histone acetyltransferase GCN5 0.0041 0.0043 0.0556
Toxoplasma gondii ABC1 family protein 0.0186 0.0348 0.8234
Echinococcus multilocularis transcription factor btf3 0.0034 0.0027 0.0023
Schistosoma mansoni lamin 0.0079 0.0123 0.0287
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0024 0.002
Echinococcus granulosus sex peptide receptor 0.0023 0.0005 0.0003
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.0096 0.0092
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0068 0.01 0.0234
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0064 0.0091 0.0764
Echinococcus multilocularis neuropeptide receptor A26 0.0487 0.0984 0.0981
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0015 0.0016
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0037 0.0077
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0024 0.002
Trichomonas vaginalis alpha-glucosidase, putative 0.0053 0.0067 0.053
Brugia malayi Eukaryotic aspartyl protease family protein 0.0068 0.01 0.0486
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Echinococcus multilocularis lamin 0.0079 0.0123 0.0119
Onchocerca volvulus 0.0035 0.0029 0.0236
Mycobacterium tuberculosis Probable lipase LipE 0.0186 0.0348 0.0499
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0068 0.01 0.0511
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0028 0.0015 0.0016
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0142 0.0256 0.7628
Onchocerca volvulus 0.0028 0.0015 0.0095
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0062 0.0087 0.2473
Loa Loa (eye worm) hypothetical protein 0.0097 0.016 0.0818
Schistosoma mansoni protein kinase 0.0041 0.0042 0.0098
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0087 0.0204
Schistosoma mansoni biogenic amine receptor 0.0023 0.0005 0.0012
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0037 0.0088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.0075
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0077 0.0118 0.0114
Schistosoma mansoni hypothetical protein 0.0244 0.0472 0.1105
Onchocerca volvulus 0.0028 0.0015 0.0095
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0024 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0012 0.002
Schistosoma mansoni hypothetical protein 0.0023 0.0005 0.0012
Echinococcus multilocularis smad 0.0057 0.0077 0.0073
Loa Loa (eye worm) hypothetical protein 0.0133 0.0236 0.1207
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.0168 0.0311 0.7351
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0037 0.0162
Giardia lamblia DINP protein human, muc B family 0.0038 0.0037 0.0502
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0087 0.0445
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0172 0.0319 0.3091
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0118 0.0498
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0005 0.0001
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Trypanosoma brucei acetyl-CoA carboxylase 0.0168 0.0311 0.082
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.001 0.0137
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0057 0.0053
Brugia malayi Glycosyl hydrolases family 31 protein 0.0142 0.0256 0.1287
Echinococcus multilocularis g protein coupled receptor 0.0023 0.0005 0.0001
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0005 0.0026
Loa Loa (eye worm) neuropeptide F receptor 0.0023 0.0005 0.0026
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.016 0.0365
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0012 0.002
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0041 0.0042 0.0038
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0041 0.0042 0.0089
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0041 0.0042 0.0038
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0118 0.1533
Loa Loa (eye worm) hypothetical protein 0.0186 0.0348 0.1781
Schistosoma mansoni hypothetical protein 0.069 0.1413 0.3312
Schistosoma mansoni DNA polymerase eta 0.0038 0.0037 0.0086
Plasmodium vivax SET domain protein, putative 0.0064 0.0091 0.1278
Brugia malayi AMP-binding enzyme family protein 0.0095 0.0157 0.0778
Echinococcus multilocularis histone acetyltransferase MYST2 0.0055 0.0071 0.0067
Trichomonas vaginalis ribonuclease H1, putative 0.022 0.0421 0.3642
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0053 0.0067 0.1889
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Schistosoma mansoni hypothetical protein 0.0179 0.0334 0.0782
Schistosoma mansoni transcription factor btf3 0.0034 0.0027 0.0064
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0064 0.0091 0.0233
Giardia lamblia Kinase, CMGC GSK 0.0053 0.0068 0.1271
Brugia malayi RNA binding protein 0.0062 0.0087 0.0421
Trichomonas vaginalis alpha-glucosidase, putative 0.0142 0.0256 0.2185
Onchocerca volvulus 0.0028 0.0015 0.0095
Loa Loa (eye worm) AUR protein kinase 0.0062 0.0087 0.0444
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0064 0.0091 0.0126
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0005 0.0003
Brugia malayi Protein kinase domain containing protein 0.0485 0.0979 0.5001
Loa Loa (eye worm) hypothetical protein 0.0095 0.0157 0.0801
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0005 0.0026
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0055 0.0071 0.034
Echinococcus granulosus biogenic amine 5HT receptor 0.0534 0.1085 0.2535
Brugia malayi MH2 domain containing protein 0.0057 0.0077 0.037
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.2041 0.4267 0.4265
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0179 0.0334 0.0773
Loa Loa (eye worm) hypothetical protein 0.0081 0.0128 0.0655
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0037 0.0785
Schistosoma mansoni pyruvate carboxylase 0.0064 0.0091 0.0213
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0122 0.0213 0.3088
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0006 0.0004
Onchocerca volvulus 0.0053 0.0068 0.0619
Trypanosoma brucei glucosidase, putative 0.0142 0.0256 0.0673
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0041 0.0042 0.0626
Schistosoma mansoni neuropeptide f receptor 76f 0.0023 0.0005 0.0012
Brugia malayi Pepsin A precursor 0.0068 0.01 0.0486
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0023 0.0005 0.0001
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0062 0.0087 0.2473
Echinococcus granulosus G protein coupled receptor 139 0.0023 0.0005 0.0003
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0411 0.3552
Schistosoma mansoni lipoxygenase 0.1427 0.297 0.696
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.0096 0.0216
Loa Loa (eye worm) MBCTL1 0.0055 0.0071 0.0365
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0071 0.0106 0.1372
Loa Loa (eye worm) latrophilin receptor protein 2 0.0113 0.0195 0.0996
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0077 0.0118 0.0275
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0005 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0186 0.0348 0.5101
Schistosoma mansoni hypothetical protein 0.0113 0.0195 0.0456
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0028 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0534 0.1085 0.5553
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0041 0.0042 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0172 0.0319 0.0747
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0357 0.071 0.3622
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0037 0.0287
Plasmodium vivax basic transcription factor 3b, putative 0.0034 0.0027 0.0323
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0142 0.0256 0.7628
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0037 0.0785
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0015 0.0095
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0037 0.0088
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0015 0.0095
Echinococcus multilocularis serotonin receptor 0.0534 0.1085 0.1081
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0028 0.0015 0.0095
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0068 0.01 0.0234
Schistosoma mansoni opsin-like receptor 0.0023 0.0005 0.0012
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0012 0.009
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0024 0.0098
Leishmania major acetyl-CoA synthetase, putative 0.0028 0.0015 0.0259
Plasmodium falciparum importin beta, putative 0.0031 0.0022 0.0248
Echinococcus multilocularis lipoxygenase domain containing protein 0.0341 0.0676 0.0673
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0024 0.0007 0.0017
Trypanosoma cruzi ribonuclease H1, putative 0.022 0.0421 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0077 0.0118 0.2499
Onchocerca volvulus 0.0028 0.0015 0.0095
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0028 0.0015 0.0016
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0037 0.0088
Loa Loa (eye worm) hypothetical protein 0.0026 0.001 0.0051
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0037 0.0287
Brugia malayi hypothetical protein 0.0068 0.01 0.0486
Mycobacterium ulcerans beta-lactamase 0.0186 0.0348 0.3014
Trichomonas vaginalis penicillin-binding protein, putative 0.0186 0.0348 0.2993
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0022 0.0049
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0077 0.0118 0.2722
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0015 0.0016
Schistosoma mansoni cpg binding protein 0.0039 0.0037 0.0087
Loa Loa (eye worm) hypothetical protein 0.0028 0.0015 0.0075
Schistosoma mansoni hypothetical protein 0.0023 0.0005 0.0012
Brugia malayi reverse transcriptase 0.0041 0.0042 0.0188
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0037 0.0785
Brugia malayi Carboxyl transferase domain containing protein 0.0162 0.0298 0.1506
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0122 0.0213 0.3088
Mycobacterium ulcerans acyl-CoA synthetase 0.0095 0.0157 0.1338
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0071 0.0106 0.0148
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0005 0.0012
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0028 0.0015 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0037 0.0088
Entamoeba histolytica hypothetical protein 0.0179 0.0334 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0453 0.0913 0.466
Echinococcus granulosus allatostatin A receptor 0.0023 0.0005 0.0003
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0041 0.0042 0.0038
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0062 0.0087 0.1209
Leishmania major basic transcription factor 3a, putative 0.0034 0.0027 0.0559
Echinococcus granulosus snurportin 1 0.0336 0.0665 0.155
Loa Loa (eye worm) AUR protein kinase 0.0062 0.0087 0.0444
Trypanosoma cruzi aurora B kinase, putative 0.0062 0.0087 0.1982
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0005 0.0014
Plasmodium falciparum plasmepsin VII 0.0068 0.01 0.1405
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0028 0.0015 0.0095
Trypanosoma brucei ribonuclease H1 0.022 0.0421 0.1115
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0077 0.0118 0.0275
Leishmania major importin beta-1 subunit, putative 0.0025 0.001 0.0137
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0028 0.0015 0.0095
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0023 0.0005 0.0001
Echinococcus granulosus protein kinase shaggy 0.0053 0.0068 0.015
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Loa Loa (eye worm) hypothetical protein 0.0072 0.0108 0.055
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.022 0.1893
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0062 0.0087 0.0194
Mycobacterium tuberculosis Possible maturase 0.0041 0.0042 0.0055
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.01 0.0166 0.0163
Leishmania major acetyl-CoA carboxylase, putative 0.0168 0.0311 0.7351
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.01 0.0166 0.3891
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0037 0.0088
Giardia lamblia Reverse transcriptase/endonuclease, putative 0.0041 0.0042 0.0626
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0015 0.0066
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0015 0.0095
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0074 0.0113 0.0158
Loa Loa (eye worm) hypothetical protein 0.0244 0.0472 0.2415
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0068 0.0171
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0005 0.0001
Treponema pallidum replicative DNA helicase (dnaB) 0.0375 0.0747 1
Schistosoma mansoni intermediate filament proteins 0.0079 0.0123 0.0287
Echinococcus granulosus peptide allatostatin:somatostatin 0.0023 0.0005 0.0003
Echinococcus multilocularis geminin 0.069 0.1413 0.141
Plasmodium falciparum plasmepsin II 0.0068 0.01 0.1405
Plasmodium falciparum plasmepsin X 0.0068 0.01 0.1405
Mycobacterium leprae conserved hypothetical protein 0.0186 0.0348 0.1505
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0068 0.1536
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0064 0.0091 0.1173
Schistosoma mansoni glutaminase 0.0563 0.1145 0.2683
Plasmodium vivax acyl-CoA synthetase, putative 0.0071 0.0106 0.1494
Echinococcus granulosus mothers against decapentaplegic 6 0.0026 0.001 0.0014
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.005 0.0062 0.0317
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0113 0.0195 0.0447
Loa Loa (eye worm) hypothetical protein 0.0051 0.0063 0.0322
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.022 0.0314
Wolbachia endosymbiont of Brugia malayi ribonuclease HI 0.022 0.0421 0.5621
Loa Loa (eye worm) hypothetical protein 0.0078 0.012 0.0612
Mycobacterium ulcerans lipase LipD 0.0186 0.0348 0.3014
Mycobacterium tuberculosis Probable replicative DNA helicase DnaB 0.3284 0.6894 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.0091 0.0214
Echinococcus granulosus rho-associated protein kinase 1 0.0157 0.0288 0.0666
Brugia malayi acetyltransferase, GNAT family protein 0.0155 0.0284 0.1431
Brugia malayi mothers against decapentaplegic homolog 3 0.0026 0.001 0.0026
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0028 0.0015 0.0016
Brugia malayi reverse transcriptase 0.0041 0.0042 0.0188
Loa Loa (eye worm) twinkle helicase 0.0107 0.0182 0.0931
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0087 0.0204
Echinococcus multilocularis snurportin 1 0.0336 0.0665 0.0661
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0057 0.0077 0.0181
Loa Loa (eye worm) hypothetical protein 0.0309 0.0608 0.3114
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0005 0.0001
Loa Loa (eye worm) MH2 domain-containing protein 0.0057 0.0077 0.0395
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.022 0.5172
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0037 0.0048
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0015 0.0016
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0163 0.0382
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0037 0.0088
Brugia malayi MH1 domain containing protein 0.0032 0.0023 0.0092
Loa Loa (eye worm) hypothetical protein 0.0341 0.0676 0.3464
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0118 0.1533
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0388 0.3347
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0023 0.0004 0.0009
Plasmodium falciparum plasmepsin IV 0.0068 0.01 0.1405
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0388 0.3347
Trichomonas vaginalis reverse transcriptases, putative 0.0041 0.0042 0.0303
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0024 0.0056
Echinococcus multilocularis microtubule associated protein 2 0.1397 0.2906 0.2903
Brugia malayi exodeoxyribonuclease III family protein 0.0074 0.0113 0.0554
Onchocerca volvulus 0.0041 0.0042 0.0361
Onchocerca volvulus 0.037 0.0738 0.722
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0388 0.3347
Brugia malayi mbt repeat family protein 0.0048 0.0057 0.0268
Trichomonas vaginalis D-aminoacylase, putative 0.0186 0.0348 0.2993
Brugia malayi mbt repeat family protein 0.0048 0.0057 0.0268
Brugia malayi follicle stimulating hormone receptor 0.0946 0.1953 1
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.0999 0.0996
Loa Loa (eye worm) beta-lactamase 0.0186 0.0348 0.1781
Giardia lamblia Histone acetyltransferase GCN5 0.0041 0.0043 0.0654
Chlamydia trachomatis replicative DNA helicase 0.0375 0.0747 1
Schistosoma mansoni hypothetical protein 0.1796 0.3749 0.8785
Echinococcus granulosus alpha 1A adrenergic receptor 0.0023 0.0005 0.0003
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0028 0.0015 0.0016
Echinococcus multilocularis orexin receptor type 2 0.0023 0.0005 0.0001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.001 0.0021
Brugia malayi hypothetical protein 0.0133 0.0236 0.1185
Brugia malayi beta-lactamase family protein 0.0186 0.0348 0.1759
Leishmania major hypothetical protein, conserved 0.0186 0.0348 0.8234
Brugia malayi hypothetical protein 0.0068 0.01 0.0486
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0186 0.0348 0.0499
Brugia malayi aspartic protease BmAsp-1, identical 0.0068 0.01 0.0486
Echinococcus multilocularis dro:myosuppressin receptor 0.0023 0.0005 0.0001
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0118 0.2727
Entamoeba histolytica hypothetical protein 0.0179 0.0334 1
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0087 0.0698
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0453 0.0913 0.2132
Trypanosoma brucei unspecified product 0.0261 0.0507 0.1345
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0068 0.0535
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0037 0.0785
Brugia malayi MH1 domain containing protein 0.0057 0.0077 0.037
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.01 0.0166 0.2397
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0095 0.0157 0.1338
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0026 0.001 0.0049
Wolbachia endosymbiont of Brugia malayi recombinase A 0.0105 0.0177 0.2326
Trichomonas vaginalis antibiotic synthetase, putative 0.0028 0.0015 0.0066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0005 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0023 0.0005 0.0003
Plasmodium falciparum ataxin-2 like protein, putative 0.0149 0.0271 0.3957
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0087 0.0204
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0068 0.01 0.0234
Trypanosoma brucei recA bacterial DNA recombination protein, putative 0.0032 0.0024 0.0053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0005 0.0012
Trypanosoma brucei unspecified product 0.0042 0.0045 0.0109
Brugia malayi hypothetical protein 0.0341 0.0676 0.3447
Loa Loa (eye worm) hypothetical protein 0.0149 0.0271 0.1387
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.0037 0.0088
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0453 0.0913 0.0909
Giardia lamblia Reverse transcriptase/endonuclease 0.0041 0.0042 0.0626
Loa Loa (eye worm) hypothetical protein 0.0534 0.1085 0.5553
Onchocerca volvulus 0.0146 0.0265 0.2563
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0118 0.2727
Schistosoma mansoni hypothetical protein 0.0113 0.0195 0.0456
Schistosoma mansoni loxhd1 0.0341 0.0676 0.1585
Schistosoma mansoni acetyl-CoA carboxylase 0.0168 0.0311 0.0728
Echinococcus multilocularis dnaJ subfamily C 6 0.0059 0.0081 0.0077
Brugia malayi CHE-14 protein 0.0041 0.0043 0.0196
Schistosoma mansoni transcription factor LCR-F1 0.0179 0.0334 0.0782
Brugia malayi Smad1 0.0057 0.0077 0.037
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0037 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0015 0.005
Echinococcus granulosus 7tm_1 domain containing protein 0.0023 0.0005 0.0003
Echinococcus multilocularis ribonuclease H1 0.022 0.0421 0.0418
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.0005 0.0022
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Brugia malayi Calcitonin receptor-like protein seb-1 0.0357 0.071 0.3622
Brugia malayi Glycosyl hydrolases family 31 protein 0.0053 0.0067 0.0321
Onchocerca volvulus 0.0084 0.0133 0.1258
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0142 0.0256 0.2185
Plasmodium vivax aspartyl protease, putative 0.0068 0.01 0.1405
Chlamydia trachomatis recombinase RecA 0.0105 0.0177 0.2326
Echinococcus granulosus expressed conserved protein 0.0091 0.0147 0.0336
Trypanosoma cruzi ribonuclease H1, putative 0.022 0.0421 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0057 0.0077 0.0395
Schistosoma mansoni smad1 5 8 and 0.0057 0.0077 0.0181
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0946 0.1953 1
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0024 0.0007 0.008
Trichomonas vaginalis ap endonuclease, putative 0.0074 0.0113 0.093
Echinococcus granulosus neuropeptide receptor 0.0023 0.0005 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0142 0.0256 0.2185
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0028 0.0015 0.0259
Schistosoma mansoni smad1 5 8 and 0.0057 0.0077 0.0181
Schistosoma mansoni Smad4 0.0057 0.0077 0.0181
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.001 0.0051
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0023 0.0005 0.0001
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0142 0.0256 0.6032
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Mycobacterium tuberculosis Probable lipase LipD 0.0186 0.0348 0.0499
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0247 0.0571
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Schistosoma mansoni hypothetical protein 0.0494 0.0999 0.2341
Schistosoma mansoni smad 0.0057 0.0077 0.0181
Leishmania major DNA polymerase kappa, putative 0.0038 0.0037 0.0785
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0037 0.0033
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0064 0.0091 0.0087
Onchocerca volvulus 0.0186 0.0348 0.3377
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0005 0.0001
Giardia lamblia Aurora kinase 0.0062 0.0087 0.1736
Brugia malayi Intermediate filament tail domain containing protein 0.0079 0.0123 0.0604
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0041 0.0042 0.0038
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0067 0.0097 0.0219
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0064 0.0091 0.0381
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0186 0.0348 0.0815
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0053 0.0067 0.053
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.016 0.0794
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0068 0.0533
Echinococcus granulosus g protein coupled receptor 0.0023 0.0005 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0015 0.005
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0074 0.0113 0.0956
Brugia malayi Muscleblind-like protein 0.0309 0.0608 0.3096
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Echinococcus granulosus importin subunit beta 1 0.0031 0.0022 0.0043
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0005 0.004
Echinococcus multilocularis protein dispatched 1 0.0047 0.0056 0.0052
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0022 0.0018
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0064 0.0091 0.2087
Echinococcus multilocularis cpg binding protein 0.0039 0.0037 0.0033
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0068 0.1536
Mycobacterium tuberculosis Conserved protein 0.0186 0.0348 0.0499
Brugia malayi serine/threonine kinase 12 0.0062 0.0087 0.0419
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0005 0.0004
Schistosoma mansoni Replicative DNA helicase 0.0375 0.0747 0.175
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0068 0.01 0.0511
Loa Loa (eye worm) hepatopoietin HPO2 0.01 0.0166 0.0852
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.022 0.1893
Brugia malayi PHD-finger family protein 0.0031 0.0021 0.0084
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0037 0.0259
Echinococcus granulosus muscleblind protein 0.0309 0.0608 0.1417
Echinococcus multilocularis neuropeptide FF receptor 2 0.0023 0.0005 0.0001
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0064 0.0091 0.0233
Brugia malayi hypothetical protein 0.0041 0.0042 0.0188
Brugia malayi Augmenter of liver regeneration 0.01 0.0166 0.0828
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0015 0.0259
Echinococcus granulosus neuropeptides capa receptor 0.0023 0.0005 0.0003
Echinococcus granulosus serine protein kinase ATM 0.0024 0.0007 0.0008
Toxoplasma gondii aspartyl protease ASP1 0.0068 0.01 0.2296
Schistosoma mansoni alpha-glucosidase 0.0551 0.112 0.2624
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0172 0.0319 0.1632
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0005 0.0022
Schistosoma mansoni growth hormone secretagogue receptor 0.0023 0.0005 0.0012
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0106 0.0893
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0068 0.0535
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0064 0.0091 0.0204
Schistosoma mansoni survival motor neuron protein 0.0146 0.0265 0.0621
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.0005 0.004
Schistosoma mansoni adenoreceptor 0.0023 0.0005 0.0012
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0037 0.0086
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0041 0.0042 0.0038
Echinococcus granulosus acetyl coenzyme A carboxylase 1 0.0168 0.0311 0.072
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0047 0.0056 0.0749
Brugia malayi Latrophilin receptor protein 2 0.0113 0.0195 0.0973
Leishmania major 4-coumarate:coa ligase-like protein 0.0095 0.0157 0.3656
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0037 0.0088
Echinococcus multilocularis rhodopsin orphan GPCR 0.0023 0.0005 0.0001
Echinococcus granulosus mothers against decapentaplegic 5 0.0057 0.0077 0.0172
Onchocerca volvulus 0.0079 0.0123 0.1158
Echinococcus granulosus histone acetyltransferase MYST2 0.0055 0.0071 0.0158
Plasmodium falciparum ataxin-2 like protein, putative 0.0149 0.0271 0.3957
Schistosoma mansoni biogenic amine (5HT) receptor 0.0534 0.1085 0.2542
Echinococcus multilocularis musashi 0.0079 0.0123 0.0119
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0015 0.0095
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0057 0.0125
Mycobacterium tuberculosis Conserved protein 0.0186 0.0348 0.0499
Echinococcus multilocularis Smad4 0.0057 0.0077 0.0073
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0077 0.0118 0.0267
Onchocerca volvulus 0.0341 0.0676 0.6616
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0005 0.0002
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0027 0.0559
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0053 0.0067 0.1524
Echinococcus multilocularis RNA directed DNA polymerase (reverse transcriptase) 0.0041 0.0042 0.0038
Plasmodium vivax aspartyl protease, putative 0.0068 0.01 0.1405
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0388 0.3347
Trichomonas vaginalis importin beta-1, putative 0.0025 0.001 0.0021
Mycobacterium ulcerans hypothetical protein 0.0186 0.0348 0.3014
Loa Loa (eye worm) MH2 domain-containing protein 0.0844 0.1738 0.8897
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0037 0.0086
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0118 0.0998
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0023 0.0005 0.0001
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0057 0.0134
Loa Loa (eye worm) hypothetical protein 0.0032 0.0023 0.0117
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0028 0.0015 0.0095
Schistosoma mansoni phosphoglucomutase 0.022 0.0421 0.0988
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0074 0.0113 0.2613
Schistosoma mansoni myelin transcription factor 1 myt1 0.0055 0.0071 0.0167
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0186 0.0348 0.3014
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0023 0.0005 0.0012
Onchocerca volvulus Huntingtin homolog 0.0133 0.0236 0.2274
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0068 0.1536
Trichomonas vaginalis penicillin-binding protein, putative 0.0186 0.0348 0.2993
Trichomonas vaginalis alpha-glucosidase, putative 0.0142 0.0256 0.2185
Onchocerca volvulus 0.0064 0.0091 0.085
Schistosoma mansoni hypothetical protein 0.004 0.004 0.0094
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0041 0.0042 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0027 0.0176
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0077 0.0118 0.2722
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.0091 0.2093
Echinococcus granulosus microtubule associated protein 2 0.1397 0.2906 0.6807
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0118 0.0114
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0247 0.0243
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0357 0.071 0.3638
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0068 0.01 0.0234
Onchocerca volvulus 0.0292 0.0573 0.5601
Schistosoma mansoni amine GPCR 0.0023 0.0005 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0186 0.0348 0.8234
Onchocerca volvulus 0.0341 0.0676 0.6616
Leishmania major protein kinase, putative 0.0062 0.0087 0.1982
Onchocerca volvulus 0.0186 0.0348 0.3377
Brugia malayi DnaJ domain containing protein 0.0059 0.0081 0.039
Schistosoma mansoni cpg binding protein 0.0035 0.0029 0.0068
Entamoeba histolytica hypothetical protein 0.0179 0.0334 1
Brugia malayi isocitrate dehydrogenase 0.0032 0.0024 0.0098
Echinococcus granulosus aurora kinase A 0.0062 0.0087 0.0194
Brugia malayi beta-NAC-like protein 0.0034 0.0027 0.0114
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0047 0.0056 0.1243
Schistosoma mansoni rab6-interacting 0.0341 0.0676 0.1585
Trichomonas vaginalis alpha-glucosidase, putative 0.0142 0.0256 0.2185
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0077 0.0118 0.097
Schistosoma mansoni hypothetical protein 0.004 0.004 0.0094
Brugia malayi TAR-binding protein 0.0062 0.0087 0.0421
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0095 0.0157 0.1338
Plasmodium vivax importin-beta 2, putative 0.0031 0.0022 0.0248
Loa Loa (eye worm) hypothetical protein 0.0357 0.071 0.3638
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0023 0.0005 0.0012
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0087 0.0698
Onchocerca volvulus 0.0068 0.01 0.0934
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0023 0.0005 0.0003
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0062 0.0084
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0118 0.1514
Mycobacterium tuberculosis RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. 0.3015 0.6324 0.9172
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0028 0.0015 0.0047
Loa Loa (eye worm) hypothetical protein 0.0068 0.01 0.0511
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0068 0.1276
Loa Loa (eye worm) hypothetical protein 0.0309 0.0608 0.3114
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Trichomonas vaginalis reverse transcriptases, putative 0.0041 0.0042 0.0303
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0186 0.0348 0.1781
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0028 0.0015 0.005
Mycobacterium leprae PROBABLE REPLICATIVE DNA HELICASE DNAB replicative DNA helicase 0.0375 0.0747 0.3252
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.022 0.0507
Brugia malayi Probable ClpP-like protease 0.0077 0.0118 0.0579
Brugia malayi Zinc knuckle family protein 0.0041 0.0042 0.0188
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0091 0.0214
Loa Loa (eye worm) hypothetical protein 0.0068 0.01 0.0511
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0015 0.0095
Leishmania major 4-coumarate:coa ligase-like protein 0.0095 0.0157 0.3656
Onchocerca volvulus 0.005 0.0062 0.056
Onchocerca volvulus 0.0079 0.0123 0.1158
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0172 0.0319 0.1632
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0023 0.0005 0.0012
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0113 0.0195 0.0973
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0074 0.0113 0.0291
Schistosoma mansoni hypothetical protein 0.004 0.004 0.0094
Onchocerca volvulus 0.0048 0.0057 0.0515
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.022 0.0216
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0068 0.01 0.0225
Trichomonas vaginalis maltase-glucoamylase, putative 0.0053 0.0067 0.053
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0037 0.0162
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0453 0.0913 0.4674
Loa Loa (eye worm) hypothetical protein 0.0031 0.0022 0.0113
Plasmodium vivax plasmepsin V, putative 0.0068 0.01 0.1405
Schistosoma mansoni hypothetical protein 0.0113 0.0195 0.0456
Schistosoma mansoni ap endonuclease 0.0074 0.0113 0.0265
Echinococcus granulosus tachykinin peptides receptor 99D 0.0023 0.0005 0.0003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0074 0.0113 0.1602
Brugia malayi aspartic protease BmAsp-2, identical 0.0068 0.01 0.0486
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0037 0.0088
Schistosoma mansoni hypothetical protein 0.0041 0.0042 0.0098
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0005 0.0012
Loa Loa (eye worm) transcription factor SMAD2 0.0844 0.1738 0.8897
Trypanosoma brucei retrotransposon hot spot protein 4 (RHS4), interrupted 0.0261 0.0507 0.1345
Mycobacterium ulcerans pyruvate carboxylase 0.0064 0.0091 0.0764
Loa Loa (eye worm) hypothetical protein 0.0053 0.0067 0.0345
Schistosoma mansoni neuropeptide F-like receptor 0.0023 0.0005 0.0012
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0057 0.0293
Brugia malayi hypothetical protein 0.0718 0.1473 0.7534
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0053 0.0068 0.1531
Brugia malayi MH1 domain containing protein 0.0057 0.0077 0.037
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0028 0.0015 0.0047
Echinococcus granulosus lamin 0.0079 0.0123 0.0278
Echinococcus granulosus RNA directed DNA polymerase reverse transcriptase 0.0041 0.0042 0.0089
Trichomonas vaginalis alpha-glucosidase, putative 0.0142 0.0256 0.2185
Loa Loa (eye worm) hypothetical protein 0.0077 0.0118 0.0602
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0008 0.0004
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0062 0.0087 0.0083
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0024 0.002
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0074 0.0113 0.0256
Trypanosoma brucei unspecified product 0.0026 0.0012 0.002
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0047 0.0056 0.0427
Schistosoma mansoni hypothetical protein 0.0146 0.0265 0.0621
Echinococcus multilocularis neuropeptides capa receptor 0.0023 0.0005 0.0001
Schistosoma mansoni neuropeptide receptor 0.0023 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0049 0.0059 0.0304
Loa Loa (eye worm) intermediate filament protein 0.0079 0.0123 0.0628
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0118 0.0267
Brugia malayi reverse transcriptase 0.0041 0.0042 0.0188
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0172 0.0319 0.0739
Echinococcus granulosus g protein coupled receptor 0.0023 0.0005 0.0003
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0024 0.0054
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0062 0.0087 0.2473
Loa Loa (eye worm) hypothetical protein 0.0186 0.0348 0.1781
Echinococcus granulosus lamin dm0 0.0079 0.0123 0.0278
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.001 0.0051
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.0087 0.2473
Loa Loa (eye worm) hypothetical protein 0.0113 0.0195 0.0996
Echinococcus multilocularis serine protein kinase ATM 0.0024 0.0007 0.0003
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0042 0.0045 0.0231
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0015 0.0029
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0172 0.0319 0.161
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0024 0.0485
Schistosoma mansoni histamine h1 receptor 0.0023 0.0005 0.0012
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0074 0.0113 0.1602
Treponema pallidum exodeoxyribonuclease (exoA) 0.0074 0.0113 0.145
Trypanosoma brucei ingi protein (ORF1) 0.0261 0.0507 0.1345
Mycobacterium ulcerans hypothetical protein 0.0095 0.0157 0.1338
Brugia malayi beta-lactamase family protein 0.0186 0.0348 0.1759
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0023 0.0005 0.0001
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0443 0.0891 0.4562
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.0168 0.0311 0.0307
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0312 0.0614 0.3129
Loa Loa (eye worm) hypothetical protein 0.0292 0.0573 0.2936
Brugia malayi glutaminase DH11.1 0.0563 0.1145 0.5852
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0142 0.0256 0.2185
Echinococcus multilocularis fmrfamide receptor 0.0023 0.0005 0.0001
Trichomonas vaginalis sucrase-isomaltase, putative 0.0142 0.0256 0.2185
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0005 0.0001
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0053 0.0068 0.1531
Brugia malayi serine/threonine-protein kinase 6 0.0062 0.0087 0.0419
Trypanosoma brucei ingi protein (ORF1) 0.0261 0.0507 0.1345
Brugia malayi MH1 domain containing protein 0.0032 0.0023 0.0092
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Echinococcus granulosus lysosomal alpha glucosidase 0.064 0.1308 0.3059
Trypanosoma brucei SLACS reverse transcriptase, putative 0.0041 0.0042 0.0101
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0028 0.0015 0.0095
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.016 0.4699
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.064 0.1308 0.6697
Schistosoma mansoni lamin 0.0079 0.0123 0.0287
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0023 0.0005 0.0003
Brugia malayi Importin beta-1 subunit 0.0031 0.0022 0.0088
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0074 0.0113 0.0578
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0068 0.0535
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0142 0.0256 0.131
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0062 0.0145
Echinococcus granulosus tm gpcr rhodopsin 0.0023 0.0005 0.0003
Schistosoma mansoni smad1 5 8 and 0.0057 0.0077 0.0181
Echinococcus granulosus mothers against decapentaplegic 2 0.0026 0.001 0.0014
Plasmodium falciparum serine/threonine protein kinase, putative 0.0062 0.0087 0.1209
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0068 0.01 0.0234
Trichomonas vaginalis protein kinase inhibitor, putative 0.0059 0.0081 0.0648
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0095 0.0157 0.1338
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Trichomonas vaginalis glutaminase, putative 0.0563 0.1145 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Echinococcus multilocularis RUN 0.0341 0.0676 0.0673
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.01 0.0166 0.3891
Plasmodium falciparum plasmepsin VIII, putative 0.0068 0.01 0.1405
Trypanosoma cruzi PAB1-binding protein , putative 0.0149 0.0271 0.6396
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Loa Loa (eye worm) hypothetical protein 0.0055 0.0071 0.0365
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0057 0.0134
Trypanosoma cruzi transcription factor btf3, putative 0.0034 0.0027 0.0559
Toxoplasma gondii LsmAD domain-containing protein 0.0149 0.0271 0.6396
Schistosoma mansoni hypothetical protein 0.004 0.004 0.0094
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0204 0.0388 0.09
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0541
Trypanosoma brucei hypothetical protein, conserved 0.0186 0.0348 0.0918
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0062 0.0254
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0541
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0023 0.0005 0.0026
Schistosoma mansoni phosphoglucomutase 0.022 0.0421 0.0988
Trypanosoma brucei unspecified product 0.0038 0.0037 0.0088
Echinococcus granulosus dnaJ subfamily C 6 0.0059 0.0081 0.0181
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0043 0.0317
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0068 0.015
Trypanosoma brucei protein kinase, putative 0.0053 0.0068 0.0171
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0186 0.0348 0.0499
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0087 0.0421
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0068 0.01 0.0234
Loa Loa (eye worm) hypothetical protein 0.0071 0.0106 0.0541
Plasmodium falciparum plasmepsin VI 0.0068 0.01 0.1405
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0067 0.0098 0.0136
Brugia malayi intermediate filament protein 0.0079 0.0123 0.0604
Plasmodium falciparum plasmepsin I 0.0068 0.01 0.1405
Echinococcus granulosus survival motor neuron protein 1 0.0718 0.1473 0.3445
Toxoplasma gondii Erv1 / Alr family protein 0.01 0.0166 0.3891
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0028 0.0015 0.0095
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0155 0.0284 0.028
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0047 0.0056 0.1243
Schistosoma mansoni amine GPCR 0.0023 0.0005 0.0012
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0118 0.0276
Schistosoma mansoni biogenic amine receptor 0.0023 0.0005 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0453 0.0913 0.2139
Schistosoma mansoni microtubule-associated protein tau 0.1397 0.2906 0.681
Schistosoma mansoni hypothetical protein 0.0023 0.0005 0.0012
Trichomonas vaginalis alpha-glucosidase, putative 0.0053 0.0067 0.053
Loa Loa (eye worm) hypothetical protein 0.0068 0.01 0.0511
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0053 0.0068 0.015
Brugia malayi AMP-binding enzyme family protein 0.0095 0.0157 0.0778
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0057 0.0125
Entamoeba histolytica acyl-CoA synthetase, putative 0.0095 0.0157 0.4603
Echinococcus granulosus neuropeptide s receptor 0.0487 0.0984 0.23
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0053 0.0068 0.0347
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0033 0.0068
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0037 0.0949
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0087 0.0204
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.0168 0.0311 0.7351
Echinococcus multilocularis L aminoadipate semialdehyde 0.0084 0.0133 0.0129
Entamoeba histolytica acyl-CoA synthetase, putative 0.0095 0.0157 0.4603
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0113 0.0195 0.0191
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0037 0.0188
Trypanosoma brucei glycosyl hydrolase-like protein 0.0053 0.0067 0.017
Schistosoma mansoni hypothetical protein 0.0059 0.0081 0.019
Leishmania major ribonuclease H1, putative 0.022 0.0421 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0113 0.0195 0.0447
Echinococcus multilocularis zinc finger protein 0.0026 0.001 0.0006
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0068 0.0064
Echinococcus multilocularis lipoxygenase domain containing protein 0.0341 0.0676 0.0673
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.01 0.0166 0.0381
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0037 0.0785
Schistosoma mansoni acetyl-CoA synthetase 0.0028 0.0015 0.0034
Onchocerca volvulus 0.0504 0.102 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0023 0.0005 0.0001
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0024 0.0277
Trichomonas vaginalis glucosylceramidase, putative 0.0312 0.0614 0.5338
Schistosoma mansoni hypothetical protein 0.0307 0.0605 0.1417
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0043 0.0039
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0023 0.0005 0.0012
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0037 0.0048
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0053 0.0067 0.0616
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0068 0.0348
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0012 0.002
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0087 0.0445
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0388 0.3347
Echinococcus multilocularis GPCR, family 2 0.0113 0.0195 0.0191
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0087 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.0087 0.0203
Loa Loa (eye worm) hypothetical protein 0.0039 0.0038 0.0195
Leishmania major carboxylase, putative 0.0064 0.0091 0.2087
Trypanosoma cruzi hypothetical protein, conserved 0.0142 0.0256 0.6032
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0074 0.0113 0.0109
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0186 0.0348 0.0499
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0024 0.0277
Trichomonas vaginalis D-aminoacylase, putative 0.0186 0.0348 0.2993
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0023 0.0005 0.0001
Echinococcus granulosus TGF beta signal transducer SmadC 0.0057 0.0077 0.0172
Trichomonas vaginalis esterase, putative 0.0186 0.0348 0.2993
Echinococcus multilocularis lysosomal alpha glucosidase 0.064 0.1308 0.1305
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0023 0.0005 0.0012
Echinococcus granulosus cpg binding protein 0.0039 0.0037 0.0078
Loa Loa (eye worm) AUR protein kinase 0.0062 0.0087 0.0444
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0005 0.0012
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0028 0.0015 0.0016
Schistosoma mansoni hypothetical protein 0.0336 0.0665 0.1557
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0023 0.0005 0.0012
Echinococcus multilocularis neuropeptide s receptor 0.0487 0.0984 0.0981
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0064 0.0091 0.0764
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0095 0.0157 0.0668
Loa Loa (eye worm) G-protein coupled receptor 0.0023 0.0005 0.0026
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0064 0.0091 0.0214
Trichomonas vaginalis maltase-glucoamylase, putative 0.0142 0.0256 0.2185
Schistosoma mansoni protein kinase 0.0062 0.0087 0.0203
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0062 0.0058
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0053 0.0067 0.053
Brugia malayi Bromodomain containing protein 0.0043 0.0046 0.021
Echinococcus multilocularis neuropeptide receptor 0.0023 0.0005 0.0001
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.022 0.0515
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0068 0.01 0.0234
Trichomonas vaginalis glucosylceramidase, putative 0.0205 0.0388 0.3347
Loa Loa (eye worm) hypothetical protein 0.0186 0.0348 0.1781
Echinococcus granulosus dro:myosuppressin receptor 0.0023 0.0005 0.0003
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0038 0.0036 0.0032
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0453 0.0913 0.2139
Brugia malayi AMP-binding enzyme family protein 0.0028 0.0015 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0005 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0261 0.0507 0.1345
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Loa Loa (eye worm) hypothetical protein 0.0037 0.0033 0.017
Echinococcus granulosus g-protein coupled receptor 0.0023 0.0005 0.0003
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.01 0.0166 0.3891
Onchocerca volvulus Ribonuclease H1 homolog 0.022 0.0421 0.4103
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.016 0.0156
Echinococcus granulosus lipoxygenase domain containing protein 0.0341 0.0676 0.1578
Schistosoma mansoni patched 1 0.0041 0.0043 0.0101
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0068 0.01 0.0234
Brugia malayi Pao retrotransposon peptidase family protein 0.0041 0.0042 0.0188
Toxoplasma gondii ribonuclease HI protein 0.022 0.0421 1
Entamoeba histolytica acetyltransferase, GNAT family 0.0041 0.0043 0.1136
Loa Loa (eye worm) hypothetical protein 0.0095 0.0157 0.0801
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0015 0.0095
Mycobacterium ulcerans acyl-CoA synthetase 0.0028 0.0015 0.0095
Loa Loa (eye worm) hypothetical protein 0.0341 0.0676 0.3464
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0005 0.0007
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0172 0.0319 0.0315
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0155 0.0284 0.0665
Echinococcus granulosus serotonin receptor 0.0023 0.0005 0.0003
Schistosoma mansoni amine GPCR 0.0023 0.0005 0.0012
Trypanosoma cruzi hypothetical protein, conserved 0.0142 0.0256 0.6032
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0029 0.0016 0.0329
Leishmania major glycosyl hydrolase-like protein 0.0053 0.0067 0.1524
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0077 0.0118 0.0267
Entamoeba histolytica protein kinase domain containing protein 0.0053 0.0068 0.1898
Loa Loa (eye worm) hypothetical protein 0.0038 0.0036 0.0186
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0024 0.0029
Schistosoma mansoni bromodomain containing protein 0.007 0.0104 0.0243
Echinococcus multilocularis RNA directed DNA polymerase 0.0041 0.0042 0.0038
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0067 0.0098 0.0136
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0077 0.0118 0.3415
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.0485 0.0979 0.5014
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0028 0.0015 0.0259
Loa Loa (eye worm) hypothetical protein 0.0084 0.0133 0.0679
Schistosoma mansoni scy1(yeast) protein kinase-like 0.0041 0.0042 0.0098
Trypanosoma brucei aurora B kinase 0.0062 0.0087 0.0221
Echinococcus multilocularis G-protein coupled receptor, putative 0.0023 0.0005 0.0001
Treponema pallidum recombinase A 0.0105 0.0177 0.2308
Trichomonas vaginalis NeSL-1_NeSL reverse transcriptases, putative 0.0041 0.0042 0.0303
Echinococcus granulosus smad 0.0057 0.0077 0.0172
Trypanosoma brucei PAB1-binding protein , putative 0.0149 0.0271 0.0713
Trichomonas vaginalis AGC family protein kinase 0.0062 0.0087 0.0698
Entamoeba histolytica acyl-coA synthetase, putative 0.0095 0.0157 0.4603
Brugia malayi RNase H family protein 0.022 0.0421 0.2138
Entamoeba histolytica protein kinase, putative 0.0053 0.0068 0.1898
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0064 0.0091 0.0214
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0023 0.0005 0.0001
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Echinococcus granulosus dna polymerase kappa 0.0038 0.0037 0.0077
Echinococcus granulosus zinc finger protein 0.0026 0.001 0.0014
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0023 0.0005 0.0012
Brugia malayi hypothetical protein 0.0041 0.0042 0.0188
Echinococcus multilocularis neuropeptide Y receptor 0.0023 0.0005 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0023 0.0005 0.0012
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0028 0.0015 0.0095
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.001 0.0021
Onchocerca volvulus Huntingtin homolog 0.0133 0.0236 0.2274
Toxoplasma gondii histone lysine methyltransferase SET1 0.0074 0.0112 0.26
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0068 0.1536
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0023 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0023 0.0005 0.0026
Mycobacterium leprae Conserved hypothetical protein 0.1104 0.2288 1
Mycobacterium ulcerans recombinase A 0.0105 0.0177 0.1514
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0053 0.0068 0.1531
Schistosoma mansoni neuropeptide receptor 0.0023 0.0005 0.0012
Mycobacterium ulcerans glutaminase 0.0563 0.1145 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0038 0.0036 0.0076
Brugia malayi Bromodomain containing protein 0.0082 0.0129 0.0635
Plasmodium vivax aspartyl proteinase, putative 0.0068 0.01 0.1405
Schistosoma mansoni hypothetical protein 0.069 0.1413 0.3312
Plasmodium vivax ataxin-2 like protein, putative 0.0149 0.0271 0.3957
Echinococcus granulosus neutral alpha glucosidase AB 0.0142 0.0256 0.0591
Trichomonas vaginalis glucosylceramidase, putative 0.0216 0.0411 0.3552
Onchocerca volvulus 0.0186 0.0348 0.3377

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 6.3096 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (binding) = 15.8489 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Identifying the Cell-Membrane Permeable IMPase Inhibitors: Potentiation with Lithium. (Class of assay: confirmatory) [Related pubchem assays: 901 ] ChEMBL. No reference
Potency (functional) 89.1251 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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