Detailed information for compound 1399033

Basic information

Technical information
  • TDR Targets ID: 1399033
  • Name: N-[2-(4-chlorophenyl)ethyl]-2-pyridin-2-ylqui noline-4-carboxamide
  • MW: 387.862 | Formula: C23H18ClN3O
  • H donors: 1 H acceptors: 3 LogP: 4.68 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)CCNC(=O)c1cc(nc2c1cccc2)c1ccccn1
  • InChi: 1S/C23H18ClN3O/c24-17-10-8-16(9-11-17)12-14-26-23(28)19-15-22(21-7-3-4-13-25-21)27-20-6-2-1-5-18(19)20/h1-11,13,15H,12,14H2,(H,26,28)
  • InChiKey: YNGIGKPRMXIZGU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[2-(4-chlorophenyl)ethyl]-2-(2-pyridyl)quinoline-4-carboxamide
  • N-[2-(4-chlorophenyl)ethyl]-2-(2-pyridyl)-4-quinolinecarboxamide
  • N-[2-(4-chlorophenyl)ethyl]-2-(2-pyridyl)cinchoninamide
  • N-[2-(4-chlorophenyl)ethyl]-2-pyridin-2-yl-quinoline-4-carboxamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens SMAD family member 2 Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens polo-like kinase 1 Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania mexicana protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania infantum protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Brugia malayi MH2 domain containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Leishmania braziliensis protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni serine/threonine protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) PLK/PLK1 protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K06631 polo-like kinase 1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Echinococcus multilocularis serine:threonine protein kinase PLK1 Get druggable targets OG5_127396 All targets in OG5_127396
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) MH2 domain-containing protein Get druggable targets OG5_131716 All targets in OG5_131716
Brugia malayi serine/threonine-protein kinase plk-2 Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Leishmania major protein kinase, putative,polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Giardia lamblia Kinase, PLK Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma congolense protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma brucei gambiense polo-like protein kinase,protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Onchocerca volvulus Serine\/threonine kinase homolog Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) transcription factor SMAD2 Get druggable targets OG5_131716 All targets in OG5_131716
Schistosoma japonicum Serine/threonine-protein kinase PLK1, putative Get druggable targets OG5_127396 All targets in OG5_127396
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Trypanosoma brucei polo-like protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trypanosoma cruzi polo-like protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Entamoeba histolytica serine/threonine protein kinase, putative Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Candida albicans protein serine/threonine kinase Get druggable targets OG5_127396 All targets in OG5_127396
Trichomonas vaginalis CAMK family protein kinase Get druggable targets OG5_127396 All targets in OG5_127396
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Brugia malayi MH2 domain containing protein SMAD family member 2 467 aa 405 aa 31.6 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0012 0.0122 0.0177
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.5351 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0122 0.0122
Schistosoma mansoni hypothetical protein 0.0019 0.0473 0.0473
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0122 0.0122
Schistosoma mansoni hypothetical protein 0.0019 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0012 0.0122 0.0177
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.5351 0.5351
Loa Loa (eye worm) hypothetical protein 0.0012 0.0122 0.0177
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.6896 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.5351 0.5
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0122 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.5351 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0122 0.0122
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.2331 0.2331
Giardia lamblia Kinase, PLK 0.0114 0.5351 0.5
Loa Loa (eye worm) hypothetical protein 0.006 0.2586 0.375
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.2586 0.375
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0122 0.0177
Schistosoma mansoni coup transcription factor 0.0012 0.0122 0.0122
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0122 0.0122
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.2331 0.338
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0114 0.5351 0.5351
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0114 0.5351 0.5351
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0122 0.0122
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0019 0.0473 0.0473
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0122 0.0177
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0122 0.0177
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0012 0.0122 0.0177
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.2331 0.338
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0473 0.0473
Brugia malayi steroid hormone receptor 0.0012 0.0122 0.0177
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0122 0.0122
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0122 0.0177
Echinococcus granulosus GPCR family 2 0.0019 0.0473 0.0473
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0122 0.0177
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0122 0.0177
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0122 0.0122
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.2586 0.375
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0122 0.0122
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.2586 0.375
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.2331 0.2331
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0114 0.5351 0.7759
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.5351 1
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0473 0.0686
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.2331 0.2331
Entamoeba histolytica serine/threonine protein kinase, putative 0.0114 0.5351 0.5
Loa Loa (eye worm) hypothetical protein 0.0012 0.0122 0.0177
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0122 0.0177
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0122 0.0228
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0122 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.5351 1
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.6896 1
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.1608 0.2332
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0122 0.0177
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0122 0.0228
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0122 0.0177
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0122 0.0122
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0122 0.0177
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.5351 1
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0114 0.5351 0.5
Onchocerca volvulus Serine\/threonine kinase homolog 0.0114 0.5351 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0122 0.0122
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0122 0.0122
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0473 0.0686
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0122 0.0177
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.5351 1
Schistosoma mansoni hypothetical protein 0.0019 0.0473 0.0473
Trypanosoma brucei polo-like protein kinase 0.0114 0.5351 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.2331 0.2331
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0122 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0122 0.0177
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0122 0.0122
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0122 0.0122
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0473 0.0686
Schistosoma mansoni kinase 0.0058 0.2472 0.2472
Brugia malayi nuclear hormone receptor 0.0012 0.0122 0.0177
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0012 0.0122 0.0177
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0122 0.0122
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0122 0.0177
Brugia malayi ecdysteroid receptor 0.0012 0.0122 0.0177
Echinococcus multilocularis GPCR, family 2 0.0019 0.0473 0.0473
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.0012 0.0122 0.0177
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0122 0.0177
Onchocerca volvulus 0.0012 0.0122 0.0228
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0122 0.0177
Loa Loa (eye worm) hypothetical protein 0.0019 0.0473 0.0686
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0122 0.0122
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0122 0.0177
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.5351 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0122 0.0122
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.2331 0.2331
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0122 0.0177
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0122 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0122 0.0177
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0122 0.0122
Brugia malayi serine/threonine-protein kinase plk-2 0.0114 0.5351 0.7759
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0122 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0122 0.0177
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0122 0.0122
Brugia malayi nuclear receptor NHR-88 0.0012 0.0122 0.0177
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.2331 0.2331
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0122 0.0122
Schistosoma mansoni hypothetical protein 0.0041 0.1608 0.1608
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0473 0.0473
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.5351 0.5
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0122 0.0177
Loa Loa (eye worm) hypothetical protein 0.0041 0.1608 0.2332
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0122 0.0122
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0122 0.0177
Brugia malayi MH2 domain containing protein 0.0144 0.6896 1
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0122 0.0228
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0122 0.0122
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0122 0.0122
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.2331 0.2331
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0122 0.0177
Schistosoma mansoni hypothetical protein 0.0019 0.0473 0.0473
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0122 0.0177
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0019 0.0473 0.0473
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0122 0.0177
Loa Loa (eye worm) hypothetical protein 0.0012 0.0122 0.0177

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.8913 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.1623 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860] ChEMBL. No reference
Potency (functional) 8.9125 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860] ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 12.9953 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.526 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 18.8876 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 20.5878 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 23.1093 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) 25.1189 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS of TDP-43 Inhibitors. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23
Homo sapiens ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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