TDR Targets

Basic information

Technical information

TDR Targets ID: 1403401
Name: (6Z)-1-[(4-fluorophenyl)methyl]-8-(4-methoxyp henyl)-4-[(E)-2-phenylethenyl]sulfonyl-5,8-di hydro-3H-1,4-diazocin-2-one
MW: 506.588 | Formula: C28H27FN2O4S
H donors: 0 H acceptors: 3 LogP: 4.51 Rotable bonds: 7
Rule of 5 violations (Lipinski): 2
SMILES: COc1ccc(cc1)C1C=CCN(CC(=O)N1Cc1ccc(cc1)F)S(=O)(=O)/C=C/c1ccccc1
InChi: 1S/C28H27FN2O4S/c1-35-26-15-11-24(12-16-26)27-8-5-18-30(36(33,34)19-17-22-6-3-2-4-7-22)21-28(32)31(27)20-23-9-13-25(29)14-10-23/h2-17,19,27H,18,20-21H2,1H3/b8-5-,19-17+
InChiKey: DCTNPDNRYKVBHB-IERIWBHQSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

(6Z)-1-[(4-fluorophenyl)methyl]-8-(4-methoxyphenyl)-4-[(E)-2-phenylvinyl]sulfonyl-5,8-dihydro-3H-1,4-diazocin-2-one
(6Z)-1-(4-fluorobenzyl)-8-(4-methoxyphenyl)-4-[(E)-2-phenylvinyl]sulfonyl-5,8-dihydro-3H-1,4-diazocin-2-one
MLS000863220
SMR000465299

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	glucagon-like peptide 1 receptor	Starlite/ChEMBL	No references
Homo sapiens	SMAD family member 2	Starlite/ChEMBL	No references
Influenza A virus	Nonstructural protein 1	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Brugia malayi	MH2 domain containing protein	Get druggable targets OG5_131716	All targets in OG5_131716
Loa Loa (eye worm)	MH2 domain-containing protein	Get druggable targets OG5_131716	All targets in OG5_131716
Loa Loa (eye worm)	transcription factor SMAD2	Get druggable targets OG5_131716	All targets in OG5_131716

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Mycobacterium tuberculosis	Hypothetical protein	Nonstructural protein 1	230 aa	202 aa	23.8 %
Brugia malayi	MH2 domain containing protein	SMAD family member 2	467 aa	405 aa	31.6 %
Loa Loa (eye worm)	pigment dispersing factor receptor c	glucagon-like peptide 1 receptor	463 aa	388 aa	25.8 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0438	0.4633	1
Entamoeba histolytica	cysteine proteinase, putative	0.0237	0.1878	0.4054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0438	0.4633	1
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Giardia lamblia	Cathepsin B precursor	0.0326	0.3093	1
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0521	0.0521
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Plasmodium vivax	vivapain-2	0.0438	0.4633	1
Trypanosoma cruzi	cruzipain precursor, putative	0.0438	0.4633	0.4633
Leishmania major	cathepsin L-like protease	0.0438	0.4633	1
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0438	0.4633	0.4633
Schistosoma mansoni	cathepsin F (C01 family)	0.0438	0.4633	0.4633
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Onchocerca volvulus	Cathepsin F homolog	0.0438	0.4633	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0438	0.4633	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0438	0.4633	1
Echinococcus granulosus	cathepsin L cysteine protease	0.0237	0.1878	0.1878
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Echinococcus granulosus	cathepsin l1	0.0438	0.4633	0.4633
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0438	0.4633	1
Treponema pallidum	fructose-bisphosphate aldolase	0.03	0.2744	0.5
Entamoeba histolytica	cysteine proteinase, putative	0.0301	0.2755	0.5946
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Echinococcus multilocularis	cathepsin L	0.0237	0.1878	0.1878
Trypanosoma cruzi	cysteine peptidase, putative	0.0237	0.1878	0.1878
Onchocerca volvulus		0.0438	0.4633	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0438	0.4633	1
Brugia malayi	Cathepsin L-like precursor	0.0438	0.4633	0.4633
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0137	0.0521	0.0521
Leishmania major	cathepsin L-like protease	0.0438	0.4633	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0438	0.4633	1
Entamoeba histolytica	cysteine proteinase 1, putative	0.0237	0.1878	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0438	0.4633	1
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0438	0.4633	0.4633
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0237	0.1878	0.1878
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.03	0.2744	0.5923
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0438	0.4633	1
Brugia malayi	Papain family cysteine protease containing protein	0.0438	0.4633	0.4633
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0438	0.4633	1
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0237	0.1878	0.1878
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.03	0.2744	0.5923
Brugia malayi	Papain family cysteine protease containing protein	0.0237	0.1878	0.1878
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0438	0.4633	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Plasmodium vivax	unspecified product	0.0137	0.0521	0.1123
Echinococcus granulosus	cysteine protease	0.0237	0.1878	0.1878
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0326	0.3093	0.3093
Trypanosoma cruzi	cysteine peptidase, putative	0.0438	0.4633	0.4633
Brugia malayi	Cathepsin L-like precursor	0.0438	0.4633	0.4633
Echinococcus multilocularis	cathepsin L cysteine protease	0.0438	0.4633	0.4633
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0438	0.4633	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0326	0.3093	0.6676
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0438	0.4633	0.4633
Trypanosoma cruzi	cysteine peptidase, putative	0.0438	0.4633	0.4633
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0438	0.4633	1
Loa Loa (eye worm)	ctsf protein	0.0438	0.4633	0.4633
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0438	0.4633	1
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Onchocerca volvulus		0.0438	0.4633	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.03	0.2744	0.5923
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0438	0.4633	1
Giardia lamblia	Cathepsin B precursor	0.0326	0.3093	1
Onchocerca volvulus		0.0438	0.4633	1
Entamoeba histolytica	cysteine proteinase, putative	0.0237	0.1878	0.4054
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0326	0.3093	0.3093
Trypanosoma cruzi	cysteine peptidase, putative	0.0438	0.4633	0.4633
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0438	0.4633	0.4633
Loa Loa (eye worm)	fibroinase	0.0438	0.4633	0.4633
Loa Loa (eye worm)	transcription factor SMAD2	0.0144	0.0613	0.0613
Trypanosoma cruzi	cruzipain precursor, putative	0.0137	0.0521	0.0521
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.03	0.2744	0.5923
Echinococcus granulosus	cathepsin l1	0.0301	0.2755	0.2755
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Entamoeba histolytica	cysteine proteinase, putative	0.0237	0.1878	0.4054
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0438	0.4633	1
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0326	0.3093	0.4409
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0301	0.2755	0.2755
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Leishmania major	cathepsin L-like protease	0.0438	0.4633	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0438	0.4633	1
Loa Loa (eye worm)	MH2 domain-containing protein	0.0144	0.0613	0.0613
Loa Loa (eye worm)	cathepsin B	0.0326	0.3093	0.3093
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0438	0.4633	1
Loa Loa (eye worm)	hypothetical protein	0.0301	0.2755	0.2755
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Entamoeba histolytica	cysteine proteinase 2	0.0237	0.1878	0.4054
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0237	0.1878	0.1878
Echinococcus multilocularis	cysteine protease	0.0438	0.4633	0.4633
Entamoeba histolytica	cysteine proteinase, putative	0.0237	0.1878	0.4054
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0438	0.4633	0.4633
Entamoeba histolytica	cysteine proteinase, putative	0.0438	0.4633	1
Plasmodium vivax	vivapain-3	0.0237	0.1878	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0301	0.2755	0.5946
Trypanosoma cruzi	cysteine peptidase, putative	0.0438	0.4633	0.4633
Entamoeba histolytica	cysteine proteinase, putative	0.0438	0.4633	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Leishmania major	cathepsin L-like protease	0.0438	0.4633	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Leishmania major	cathepsin L-like protease	0.0438	0.4633	1
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0237	0.1878	0.1878
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Loa Loa (eye worm)	cysteine protease	0.0438	0.4633	0.4633
Onchocerca volvulus	Cathepsin L homolog	0.0438	0.4633	1
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.0137	0.0521	0.0521
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Mycobacterium tuberculosis	Probable fructose-bisphosphate aldolase Fba	0.0147	0.0646	0.5
Schistosoma mansoni	cathepsin s	0.0137	0.0521	0.0521
Loa Loa (eye worm)	hypothetical protein	0.0301	0.2755	0.2755
Giardia lamblia	Cathepsin B precursor	0.0326	0.3093	1
Loa Loa (eye worm)	hypothetical protein	0.0438	0.4633	0.4633
Trypanosoma cruzi	cysteine protease, putative	0.0237	0.1878	0.1878
Brugia malayi	Cathepsin L-like precursor	0.0438	0.4633	0.4633
Trypanosoma cruzi	cysteine peptidase, putative	0.0137	0.0521	0.0521
Mycobacterium leprae	Probable fructose bisphosphate aldolase Fba	0.0147	0.0646	0.5
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0438	0.4633	1
Brugia malayi	MH2 domain containing protein	0.0144	0.0613	0.0613
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0237	0.1878	0.4054
Onchocerca volvulus		0.0438	0.4633	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0438	0.4633	1
Plasmodium vivax	vivapain-2	0.0438	0.4633	1
Onchocerca volvulus		0.0438	0.4633	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0438	0.4633	1
Brugia malayi	Papain family cysteine protease containing protein	0.0237	0.1878	0.1878
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0438	0.4633	0.4633
Entamoeba histolytica	fructose-1,6-bisphosphate aldolase, putative	0.03	0.2744	0.5923
Brugia malayi	cathepsin L-like precursor	0.0301	0.2755	0.2755
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0438	0.4633	1
Leishmania major	cysteine peptidase A (CPA)	0.0438	0.4633	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.03	0.2744	0.5923
Brugia malayi	Cathepsin L-like precursor	0.0438	0.4633	0.4633
Leishmania major	cathepsin L-like protease	0.0438	0.4633	1
Brugia malayi	Cathepsin L-like precursor	0.0438	0.4633	0.4633
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0438	0.4633	1
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0237	0.1878	0.4054
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.03	0.2744	0.5923
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.03	0.2744	0.5923
Echinococcus granulosus	cathepsin L	0.0237	0.1878	0.1878
Schistosoma mansoni	cathepsin F (C01 family)	0.0301	0.2755	0.2755
Onchocerca volvulus		0.0301	0.2755	0.5946
Mycobacterium ulcerans	fructose-bisphosphate aldolase	0.0147	0.0646	0.5
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Trypanosoma cruzi	cysteine proteinase, putative	0.0237	0.1878	0.1878
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Trypanosoma cruzi	cysteine proteinase, putative	0.0237	0.1878	0.1878
Brugia malayi	Cathepsin L-like precursor	0.0438	0.4633	0.4633
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0438	0.4633	1
Leishmania major	cathepsin L-like protease	0.0438	0.4633	1
Leishmania major	cathepsin L-like protease	0.0438	0.4633	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0438	0.4633	1
Toxoplasma gondii	cathepsin B	0.0326	0.3093	0.6676
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0521	0.0521
Brugia malayi	cathepsin F-like cysteine proteinase	0.0137	0.0521	0.0521
Onchocerca volvulus		0.0438	0.4633	1
Brugia malayi	Cathepsin L-like precursor	0.0301	0.2755	0.2755
Echinococcus multilocularis	cathepsin L cysteine protease	0.0438	0.4633	0.4633
Brugia malayi	Cathepsin L-like precursor	0.0137	0.0521	0.0521
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0301	0.2755	0.2755
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0438	0.4633	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.03	0.2744	0.5923
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0237	0.1878	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0237	0.1878	0.4054
Brugia malayi	Cathepsin L-like precursor	0.0301	0.2755	0.2755
Loa Loa (eye worm)	hypothetical protein	0.0301	0.2755	0.2755
Giardia lamblia	Fructose-bisphosphate aldolase	0.03	0.2744	0.8873
Toxoplasma gondii	cathepsin CPL	0.0438	0.4633	1
Schistosoma mansoni	cathepsin F (C01 family)	0.0438	0.4633	0.4633
Onchocerca volvulus		0.0438	0.4633	1
Trichomonas vaginalis	fructose-bisphosphate aldolase, putative	0.03	0.2744	0.5923
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0301	0.2755	0.5946
Plasmodium vivax	unspecified product	0.0237	0.1878	0.4054
Echinococcus multilocularis	cysteine protease	0.0438	0.4633	0.4633
Plasmodium vivax	vivapain-1	0.0237	0.1878	0.4054
Onchocerca volvulus	Cathepsin L homolog	0.0438	0.4633	1
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0521	0.0521
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0438	0.4633	1

Activities

Activity type	Activity value	Assay description	Source	Reference
Potency (functional)	10.4179 uM	PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850]	ChEMBL.	No reference
Potency (functional)	11.2202 uM	PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	11.6891 uM	PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850]	ChEMBL.	No reference
Potency (functional)	12.5893 uM	PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b: Cytotox Counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588855, AID588860]	ChEMBL.	No reference
Potency (functional)	= 15.8489 um	PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory)	ChEMBL.	No reference
Potency (functional)	15.8489 uM	PUBCHEM_BIOASSAY: qHTS for Inhibitors of TGF-b. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588856, AID588860]	ChEMBL.	No reference
Potency (functional)	125.8925 uM	PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory)	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Homo sapiens	ChEMBL23
Plasmodium falciparum	ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL1563845

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1403401