Detailed information for compound 1407455

Basic information

Technical information
  • TDR Targets ID: 1407455
  • Name: N-(2,6-dimethylphenyl)-3-oxo-2-(thiophen-2-yl methyl)-1,4-dihydropyrido[2,1-c]pyrazin-5-ium -1-carboxamide iodide
  • MW: 519.398 | Formula: C22H22IN3O2S
  • H donors: 1 H acceptors: 2 LogP: 4.12 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=C1C[n+]2ccccc2C(N1Cc1cccs1)C(=O)Nc1c(C)cccc1C.[I-]
  • InChi: 1S/C22H21N3O2S.HI/c1-15-7-5-8-16(2)20(15)23-22(27)21-18-10-3-4-11-24(18)14-19(26)25(21)13-17-9-6-12-28-17;/h3-12,21H,13-14H2,1-2H3;1H
  • InChiKey: MWMPQUCLLOBOAT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(2,6-dimethylphenyl)-3-oxo-2-(2-thienylmethyl)-1,4-dihydropyrido[2,1-c]pyrazin-5-ium-1-carboxamide iodide
  • N-(2,6-dimethylphenyl)-3-keto-2-(2-thenyl)-1,4-dihydropyrido[2,1-c]pyrazin-5-ium-1-carboxamide iodide
  • 1-{[(2,6-dimethylphenyl)amino]carbonyl}-3-oxo-2-(thien-2-ylmethyl)-1,2,3,4-tetrahydropyrido[1,2-a]pyrazin-5-ium
  • MLS000731364
  • SMR000309639

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni tar DNA-binding protein 0.0193 0.1907 0.3783
Brugia malayi mothers against decapentaplegic homolog 3 0.0022 0.0143 0.014
Echinococcus multilocularis mothers against decapentaplegic 5 0.0049 0.042 0.04
Brugia malayi MH1 domain containing protein 0.0027 0.0196 0.0214
Brugia malayi MH2 domain containing protein 0.0715 0.7278 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0488 0.0467
Echinococcus multilocularis isocitrate dehydrogenase 0.0047 0.0401 0.0381
Echinococcus granulosus ETS transcription factor Elf 2 0.0013 0.005 0.0057
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0401 0.6315
Schistosoma mansoni ap endonuclease 0.0023 0.0153 0.0264
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0401 1
Echinococcus multilocularis mothers against decapentaplegic 6 0.0022 0.0143 0.0122
Loa Loa (eye worm) isocitrate dehydrogenase 0.0047 0.0401 0.0495
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0277 0.0512
Echinococcus multilocularis ewsr:fli fusion protein type 0.0013 0.005 0.0028
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0013 0.005 0.0028
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0298 0.0277
Loa Loa (eye worm) RNA binding protein 0.0193 0.1907 0.2576
Echinococcus multilocularis ETS transcription factor Elf 2 0.0013 0.005 0.0028
Echinococcus multilocularis ets variant gene 4 0.0013 0.005 0.0028
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0013 0.005 0.0009
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0153 0.0132
Brugia malayi transcription factor E74 isoform 0.0013 0.005 0.0011
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.0609 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0187 0.3966
Brugia malayi RNA recognition motif domain containing protein 0.0193 0.1907 0.2577
Schistosoma mansoni tar DNA-binding protein 0.0193 0.1907 0.3783
Schistosoma mansoni ets-related 0.0013 0.005 0.0057
Brugia malayi latrophilin 2 splice variant baaae 0.0341 0.3434 0.4687
Echinococcus granulosus ETS transcription factor Elf 5 0.0013 0.005 0.0057
Toxoplasma gondii isocitrate dehydrogenase 0.0047 0.0401 0.6315
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0158 0.1546 0.3059
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0187 0.3966
Brugia malayi hypothetical protein 0.0017 0.0092 0.0069
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0153 0.0264
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0488 0.0936
Schistosoma mansoni Smad4 0.0049 0.042 0.0801
Echinococcus granulosus ewsr:fli fusion protein type 0.0013 0.005 0.0057
Brugia malayi Pre-SET motif family protein 0.0037 0.0298 0.0354
Onchocerca volvulus 0.0287 0.2872 1
Echinococcus granulosus dnaJ subfamily B 0.0494 0.5004 1
Schistosoma mansoni hypothetical protein 0.0158 0.1546 0.3059
Brugia malayi isocitrate dehydrogenase 0.0047 0.0401 0.0497
Brugia malayi Pre-SET motif family protein 0.0252 0.2514 0.3417
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0334 0.0402
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0488 0.0614
Brugia malayi MH1 domain containing protein 0.0027 0.0196 0.0214
Echinococcus granulosus ETS transcription factor Elf 2 0.0013 0.005 0.0057
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0298 0.0555
Schistosoma mansoni elf1 0.0013 0.005 0.0057
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0153 0.3021
Loa Loa (eye worm) MH2 domain-containing protein 0.0715 0.7278 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0325 0.7841
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0047 0.0401 1
Schistosoma mansoni hypothetical protein 0.0013 0.005 0.0057
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0047 0.0401 1
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0325 0.7841
Loa Loa (eye worm) transcription factor SMAD2 0.0715 0.7278 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.069 0.1342
Echinococcus granulosus cpg binding protein 0.0037 0.0296 0.0552
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0298 0.0277
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0158 0.1546 0.1528
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0488 0.0616
Plasmodium vivax SET domain protein, putative 0.0037 0.0298 0.5839
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0153 0.0532
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0049 0.042 0.04
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0187 0.1354
Schistosoma mansoni Smad4 0.0022 0.0143 0.0244
Loa Loa (eye worm) ets-domain-containing protein 0.0013 0.005 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0193 0.1907 0.3783
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0401 1
Leishmania major hypothetical protein, conserved 0.0026 0.0187 0.3966
Echinococcus granulosus mothers against decapentaplegic 2 0.0022 0.0143 0.0244
Trichomonas vaginalis rotamase, putative 0.004 0.0334 0.1164
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0153 0.3021
Schistosoma mansoni ets 0.0013 0.005 0.0057
Loa Loa (eye worm) hypothetical protein 0.0499 0.506 0.6935
Brugia malayi MH2 domain containing protein 0.0022 0.0143 0.014
Schistosoma mansoni hypothetical protein 0.0158 0.1546 0.3059
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0325 0.7841
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0325 1
Loa Loa (eye worm) hypothetical protein 0.0341 0.3434 0.4686
Brugia malayi Ets-domain containing protein 0.0087 0.0819 0.1075
Loa Loa (eye worm) MH1 domain-containing protein 0.0049 0.042 0.0521
Echinococcus granulosus mothers against decapentaplegic 5 0.0049 0.042 0.0801
Schistosoma mansoni hypothetical protein 0.0158 0.1546 0.3059
Echinococcus multilocularis cpg binding protein 0.0037 0.0296 0.0276
Echinococcus multilocularis ETS transcription factor Elf 1 0.0013 0.005 0.0028
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0153 0.0154
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0193 0.1907 0.2576
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0047 0.0401 1
Echinococcus granulosus expressed protein 0.004 0.0334 0.0628
Schistosoma mansoni smad1 5 8 and 0.0049 0.042 0.0801
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0013 0.005 0.0057
Loa Loa (eye worm) D-ets-2 protein 0.0013 0.005 0.0009
Echinococcus granulosus TGF beta signal transducer SmadC 0.0049 0.042 0.0801
Brugia malayi Fli-1 protein 0.0265 0.2652 0.3608
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.5004 0.4993
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0013 0.005 0.0009
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0043 0.0044
Echinococcus granulosus ETS transcription factor Elf 1 0.0013 0.005 0.0057
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0488 0.0936
Schistosoma mansoni smad1 5 8 and 0.0049 0.042 0.0801
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0153 0.5
Loa Loa (eye worm) hypothetical protein 0.0022 0.0143 0.0138
Loa Loa (eye worm) fli-1 protein 0.0265 0.2652 0.3606
Loa Loa (eye worm) hypothetical protein 0.0026 0.0187 0.0198
Loa Loa (eye worm) hypothetical protein 0.0037 0.0298 0.0352
Brugia malayi MH2 domain containing protein 0.0049 0.042 0.0523
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0325 0.4952
Echinococcus multilocularis smad 0.0049 0.042 0.04
Echinococcus multilocularis expressed protein 0.004 0.0334 0.0314
Echinococcus granulosus GA binding protein alpha chain 0.0087 0.0819 0.1601
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0401 0.0381
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0298 0.4481
Brugia malayi Calcitonin receptor-like protein seb-1 0.0499 0.506 0.6935
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0158 0.1546 0.2079
Brugia malayi RNA binding protein 0.0193 0.1907 0.2577
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0049 0.042 0.0801
Echinococcus multilocularis protein C ets 2 0.0013 0.005 0.0028
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0153 0.0152
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0298 0.0555
Brugia malayi TAR-binding protein 0.0193 0.1907 0.2577
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0488 0.0467
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0047 0.0401 1
Echinococcus granulosus tar DNA binding protein 0.0193 0.1907 0.3783
Echinococcus multilocularis Smad4 0.0049 0.042 0.04
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0153 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0276 0.0322
Loa Loa (eye worm) hypothetical protein 0.0075 0.0689 0.0892
Loa Loa (eye worm) MH2 domain-containing protein 0.0022 0.0143 0.0138
Brugia malayi MH1 domain containing protein 0.0049 0.042 0.0523
Brugia malayi Isocitrate dehydrogenase 0.0047 0.0401 0.0497
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.2514 0.3416
Schistosoma mansoni ets-related 0.0265 0.2652 0.528
Trichomonas vaginalis rotamase, putative 0.0039 0.0325 0.113
Schistosoma mansoni hypothetical protein 0.0158 0.1546 0.3059
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0153 0.3021
Loa Loa (eye worm) hypothetical protein 0.0027 0.0196 0.0212
Loa Loa (eye worm) hypothetical protein 0.0013 0.005 0.0009
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0298 0.0555
Schistosoma mansoni rotamase 0.004 0.0334 0.0628
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0047 0.0401 1
Brugia malayi CXXC zinc finger family protein 0.0035 0.0276 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0334 0.1164
Loa Loa (eye worm) latrophilin receptor protein 2 0.0158 0.1546 0.2077
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0047 0.0401 0.0763
Brugia malayi DNA-binding protein D-ETS-3 0.0013 0.005 0.0011
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0039 0.0035
Echinococcus granulosus protein C ets 2 0.0013 0.005 0.0057
Loa Loa (eye worm) MH1 domain-containing protein 0.0022 0.0143 0.0138
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0158 0.1546 0.3059
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0153 0.3021
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0325 0.7841
Echinococcus granulosus GPCR family 2 0.0158 0.1546 0.3059
Echinococcus multilocularis ETS transcription factor Elf 2 0.0013 0.005 0.0028
Onchocerca volvulus 0.0035 0.0276 0.0487
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0043 0.0022
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0039 0.0018
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0499 0.506 0.6935
Schistosoma mansoni ap endonuclease 0.0023 0.0153 0.0264
Brugia malayi Smad1 0.0049 0.042 0.0523
Schistosoma mansoni hypothetical protein 0.0012 0.0039 0.0035
Schistosoma mansoni cpg binding protein 0.0035 0.0276 0.0511
Echinococcus granulosus ETS domain containing protein Elk 1 0.0013 0.005 0.0057
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0334 0.0404
Schistosoma mansoni gabp alpha 0.0087 0.0819 0.1601
Loa Loa (eye worm) nuclear factor I 0.0027 0.0196 0.0212
Trichomonas vaginalis set domain proteins, putative 0.0287 0.2872 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0401 0.0381
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0047 0.0401 0.0381
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0298 0.0555
Schistosoma mansoni tar DNA-binding protein 0.0193 0.1907 0.3783
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0187 0.1354
Loa Loa (eye worm) Smad1 0.0049 0.042 0.0521
Brugia malayi MH1 domain containing protein 0.0049 0.042 0.0523
Loa Loa (eye worm) hypothetical protein 0.0158 0.1546 0.2077
Onchocerca volvulus 0.0037 0.0298 0.0567
Echinococcus multilocularis GA binding protein alpha chain 0.0087 0.0819 0.08
Brugia malayi MH2 domain containing protein 0.0049 0.042 0.0523
Schistosoma mansoni cpg binding protein 0.0037 0.0296 0.0552
Echinococcus multilocularis mothers against decapentaplegic 2 0.0022 0.0143 0.0122
Brugia malayi Ets-domain containing protein 0.0087 0.0819 0.1075
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0047 0.0401 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0488 0.0936
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0047 0.0401 0.0763
Schistosoma mansoni tar DNA-binding protein 0.0193 0.1907 0.3783
Echinococcus granulosus mothers against decapentaplegic 6 0.0022 0.0143 0.0244
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0187 0.2504
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0488 0.0936
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0488 0.0936
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0047 0.0401 0.0381
Schistosoma mansoni cpg binding protein 0.0037 0.0296 0.0552
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0153 0.0532
Brugia malayi Latrophilin receptor protein 2 0.0158 0.1546 0.2079
Brugia malayi hypothetical protein 0.0026 0.0187 0.02
Schistosoma mansoni hypothetical protein 0.0013 0.005 0.0057
Schistosoma mansoni hypothetical protein 0.0341 0.3434 0.6848
Echinococcus multilocularis ETS transcription factor Elf 5 0.0013 0.005 0.0028
Echinococcus granulosus Smad4 0.0049 0.042 0.0801
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0153 0.5
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0158 0.1546 0.1528
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0087 0.0819 0.1073
Loa Loa (eye worm) hypothetical protein 0.0013 0.005 0.0009
Schistosoma mansoni hypothetical protein 0.0494 0.5004 1
Schistosoma mansoni Smad4 0.0022 0.0143 0.0244
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0187 0.1354
Brugia malayi Ets-domain containing protein 0.0013 0.005 0.0011
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0187 0.3966
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0499 0.506 0.6935
Schistosoma mansoni smad1 5 8 and 0.0049 0.042 0.0801
Echinococcus granulosus smad 0.0049 0.042 0.0801
Toxoplasma gondii exonuclease III APE 0.0023 0.0153 0.1908
Schistosoma mansoni smad 0.0049 0.042 0.0801
Treponema pallidum exodeoxyribonuclease (exoA) 0.0023 0.0153 0.5
Echinococcus multilocularis tar DNA binding protein 0.0193 0.1907 0.1889
Loa Loa (eye worm) TAR-binding protein 0.0193 0.1907 0.2576
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0298 0.0555
Echinococcus multilocularis GPCR, family 2 0.0158 0.1546 0.1528
Loa Loa (eye worm) MH2 domain-containing protein 0.0049 0.042 0.0521
Schistosoma mansoni smad 0.0022 0.0143 0.0244

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.0517 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen. (Class of assay: confirmatory) [Related pubchem assays: 1473, 1466 ] ChEMBL. No reference
Potency (functional) 35.4813 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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