Detailed information for compound 1439876

Basic information

Technical information
  • TDR Targets ID: 1439876
  • Name: 3-(benzoylamino)-N-(4-methoxybenzyl)benzamide
  • MW: 360.406 | Formula: C22H20N2O3
  • H donors: 2 H acceptors: 2 LogP: 3.5 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)CNC(=O)c1cccc(c1)NC(=O)c1ccccc1
  • InChi: 1S/C22H20N2O3/c1-27-20-12-10-16(11-13-20)15-23-21(25)18-8-5-9-19(14-18)24-22(26)17-6-3-2-4-7-17/h2-14H,15H2,1H3,(H,23,25)(H,24,26)
  • InChiKey: XMDLFIZNQOBBBY-UHFFFAOYSA-N  

Network

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Synonyms

  • STK116474
  • ZINC01126700
  • MLS000675685
  • SMR000292054

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens GNAS complex locus Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain Get druggable targets OG5_131088 All targets in OG5_131088
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K04632 guanine nucleotide binding protein (G protein), alpha stimulating, putative Get druggable targets OG5_131088 All targets in OG5_131088
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit Get druggable targets OG5_131088 All targets in OG5_131088
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723

By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Schistosoma mansoni GTP-binding protein alpha subunit gna GNAS complex locus 394 aa 450 aa 28.7 %
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Leishmania major hypothetical protein, conserved 0.0466 0.3533 0.5116
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0127 0.0109
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0262 0.1875 0.3028
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0602 0.4635 0.6738
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0109 0.0635 0.0806
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0046 0.0127 0.0112
Echinococcus multilocularis diphthine synthase 0.0037 0.0055 0.0069
Trypanosoma brucei calpain-like protein, putative 0.0348 0.2578 0.3739
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.1306 0.1874
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0327 0.2408 0.3489
Plasmodium vivax hypothetical protein, conserved 0.0068 0.0302 0.0981
Loa Loa (eye worm) hypothetical protein 0.0086 0.0452 0.0439
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0696 0.5393 0.7862
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0046 0.0127 0.0351
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0416 0.0604
Echinococcus granulosus cathepsin l cysteine peptidase 0.0342 0.2525 0.2525
Echinococcus granulosus cathepsin l1 0.0342 0.2525 0.2525
Loa Loa (eye worm) hypothetical protein 0.0059 0.0229 0.0216
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi hypothetical protein, conserved 0.035 0.2593 0.376
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Toxoplasma gondii microneme protein, putative 0.0045 0.0119 0.0319
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase isozyme L3 0.0131 0.0814 0.3074
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Entamoeba histolytica protein kinase, putative 0.0038 0.0059 0.0075
Echinococcus multilocularis dnaJ subfamily B 0.0433 0.3265 0.4143
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0046 0.0127 0.0112
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Echinococcus granulosus Dipeptidyl peptidase 9 0.0061 0.0251 0.0251
Leishmania major calpain family cysteine protease-like protein 0.0594 0.4566 0.6637
Toxoplasma gondii subtilisin SUB2 0.0058 0.0223 0.0737
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0061 0.0251 0.085
Brugia malayi calpain D 0.0313 0.2289 0.2275
Echinococcus multilocularis Ubiquitin thioesterase otubain protein 0.009 0.0484 0.0614
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0109 0.0635 0.0892
Leishmania major hypothetical protein, conserved 0.0281 0.2032 0.2909
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0411 0.0596
Loa Loa (eye worm) hypothetical protein 0.0046 0.0127 0.0114
Brugia malayi Peptidase C13 family protein 0.0037 0.0053 0.0034
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Giardia lamblia Cathepsin L precursor 0.0081 0.0412 0.1042
Entamoeba histolytica cysteine protease, putative 0.0081 0.0412 0.1495
Trypanosoma cruzi cysteine peptidase, putative 0.049 0.3726 0.5419
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0051 0.0166 0.0189
Giardia lamblia Hypothetical protein 0.0081 0.0412 0.1042
Trypanosoma brucei cysteine peptidase C (CPC) 0.0276 0.1988 0.2874
Toxoplasma gondii peptidase c13 family protein 0.0064 0.0273 0.0938
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0271 0.1954 0.2824
Brugia malayi CG8232-PA 0.0062 0.0259 0.0241
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0081 0.0411 0.0393
Giardia lamblia Cathepsin B precursor 0.0276 0.1988 0.5645
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0243 0.1728 0.2493
Echinococcus multilocularis cathepsin L cysteine protease 0.0342 0.2525 0.3205
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.1875 0.3028
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0397 0.2972 0.2972
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Onchocerca volvulus 0.0045 0.0119 0.0401
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0084 0.0435 0.0635
Trypanosoma cruzi kinesin, putative 0.0087 0.0464 0.0641
Trypanosoma cruzi kinesin, putative 0.0087 0.0464 0.0641
Giardia lamblia Cathepsin B precursor 0.0276 0.1988 0.5645
Giardia lamblia Cathepsin L precursor 0.0081 0.0412 0.1042
Entamoeba histolytica cysteine protease, putative 0.0081 0.0412 0.1495
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0086 0.0452 0.0663
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0051 0.0166 0.051
Schistosoma mansoni lamin 0.0033 0.0019 0.0004
Trypanosoma brucei hypothetical protein, conserved 0.035 0.2593 0.376
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.011 0.0649 0.0632
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0068 0.0302 0.0287
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0229 0.0214
Leishmania major pyroglutamyl-peptidase I (C15 family) 0.0451 0.3408 0.4933
Loa Loa (eye worm) hypothetical protein 0.0046 0.0127 0.0114
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0607 0.4677 0.6814
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0068 0.0302 0.0302
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0046 0.0127 0.0127
Leishmania major hypothetical protein, conserved 0.0071 0.0327 0.0401
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0438 0.3306 0.4805
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0046 0.0127 0.0161
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Loa Loa (eye worm) DOMON domain-containing protein 0.0049 0.0156 0.0142
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0064 0.0273 0.0366
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Loa Loa (eye worm) calpain family protein 1 0.0392 0.2934 0.2925
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0109 0.0635 0.0621
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0412 0.0397
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0046 0.0127 0.0123
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0019 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0081 0.0412 0.0398
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0202 0.0257
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0138 0.0873 0.1204
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0779 0.6068 1
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0241 0.1706 0.2461
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Brugia malayi calpain 7 0.0361 0.2684 0.2671
Trypanosoma brucei antigen, putative 0.0328 0.2415 0.3499
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0319 0.2343 0.3807
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0876 0.6852 1
Toxoplasma gondii cathepsin CPC1 0.0081 0.0412 0.1495
Toxoplasma gondii hypothetical protein 0.0046 0.0127 0.0351
Leishmania major hypothetical protein, conserved 0.0281 0.2032 0.2909
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Loa Loa (eye worm) hypothetical protein 0.0064 0.0273 0.026
Brugia malayi PAN domain containing protein 0.0045 0.0119 0.0101
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0046 0.0127 0.0112
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0653 0.505 0.7349
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0274 0.1975 0.2855
Toxoplasma gondii cathepsin CPC2 0.0081 0.0412 0.1495
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0337 0.2483 0.2472
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0124
Brugia malayi hypothetical protein 0.0047 0.0134 0.0116
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0342 0.2525 0.3205
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Leishmania major cathepsin L-like protease 0.049 0.3726 0.54
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0261 0.1869 0.7361
Plasmodium falciparum subtilisin-like protease 1 0.0058 0.0223 0.0682
Brugia malayi cathepsin L-like cysteine proteinase 0.0081 0.0412 0.0394
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0327 0.2408 0.3489
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0127 0.0109
Brugia malayi Ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0131 0.0814 0.0797
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0372 0.0507
Loa Loa (eye worm) hypothetical protein 0.0045 0.0119 0.0105
Giardia lamblia Furin precursor putative serine protease 0.0262 0.1875 0.5314
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.049 0.3726 0.5419
Schistosoma mansoni growth factor receptor-bound protein 0.0272 0.196 0.1948
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0372 0.2773 0.4024
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0074 0.0357 0.0883
Loa Loa (eye worm) hypothetical protein 0.0392 0.2934 0.2925
Loa Loa (eye worm) hypothetical protein 0.0081 0.0412 0.0398
Trypanosoma cruzi diphthine synthase, putative 0.0037 0.0055 0.0041
Onchocerca volvulus 0.0072 0.0338 0.1273
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0082 0.0416 0.0528
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Leishmania major calpain protease-like protein 0.0274 0.1975 0.2826
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0243 0.1728 0.2493
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0076 0.0372 0.0359
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0104 0.0594 0.0581
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.1875 0.3028
Entamoeba histolytica peptidase, C54 family 0.0086 0.0452 0.1657
Schistosoma mansoni calpain (C02 family) 0.0328 0.2415 0.2403
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0229 0.0214
Schistosoma mansoni cathepsin C 0.0081 0.0412 0.0397
Loa Loa (eye worm) hypothetical protein 0.0062 0.0259 0.0246
Brugia malayi PAN domain containing protein 0.0045 0.0119 0.0101
Entamoeba histolytica peptidase, C54 family 0.0205 0.1416 0.5536
Brugia malayi PAN domain containing protein 0.0045 0.0119 0.0101
Toxoplasma gondii subtilisin SUB6 0.0058 0.0223 0.0737
Trypanosoma cruzi cysteine proteinase, putative 0.0191 0.1306 0.1874
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0602 0.4635 0.6752
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0118 0.0712 0.2704
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0182 0.1232 0.4839
Leishmania major trypanothione synthetase, putative 0.0071 0.0327 0.0401
Entamoeba histolytica cysteine protease, putative 0.0342 0.2525 1
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0086 0.0452 0.0437
Onchocerca volvulus 0.0081 0.0412 0.1567
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0205 0.1416 0.2036
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Loa Loa (eye worm) fibroinase 0.0342 0.2525 0.2515
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0229 0.0214
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0046 0.0127 0.0127
Giardia lamblia Cysteine protease 0.0081 0.0412 0.1042
Trichomonas vaginalis calpain, putative 0.0241 0.1706 0.2748
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0342 0.2525 0.2515
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0127 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0081 0.0412 0.0596
Brugia malayi Subtilase family protein 0.0058 0.0223 0.0205
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0276 0.1988 0.1976
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0119 0.0105
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0086 0.0452 0.0623
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0241 0.1706 0.2748
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0051 0.0166 0.051
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0435 0.0598
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Echinococcus multilocularis transmembrane protease serine 3 0.0059 0.0229 0.0291
Plasmodium vivax vivapain-1 0.0191 0.1306 0.4958
Onchocerca volvulus 0.0049 0.0156 0.0546
Trichomonas vaginalis AGC family protein kinase 0.0038 0.0059 0.001
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0327 0.2408 0.3462
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0046 0.0127 0.0123
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0051 0.0166 0.0444
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0081 0.0412 0.0596
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0319 0.2343 0.3807
Trypanosoma cruzi small myristoylated protein 1-1 0.0438 0.3302 0.4799
Trypanosoma brucei Calpain-like protein 1.2 0.0672 0.5201 0.758
Onchocerca volvulus 0.0342 0.2525 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.046 0.3482 0.5063
Echinococcus granulosus Mastin 0.0059 0.0229 0.0229
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0081 0.0412 0.0596
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0704 0.546 0.7953
Echinococcus multilocularis epidermal growth factor receptor 0.0264 0.1898 0.2408
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Brugia malayi cathepsin Z-like cysteine proteinase 0.0081 0.0412 0.0394
Toxoplasma gondii ubiquitin thioesterase otubain-like family protein 0.009 0.0484 0.1787
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0417 0.3138 0.4536
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0319 0.2343 0.3807
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0046 0.0127 0.0123
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0229 0.0214
Entamoeba histolytica cysteine protease inhibitor 2 (EhICP2) 0.0245 0.1742 0.6848
Leishmania major cathepsin L-like protease 0.0342 0.2525 0.3635
Echinococcus granulosus cathepsin b 0.0565 0.4335 0.4335
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0417 0.3138 0.4559
Entamoeba histolytica cysteine proteinase 1, putative 0.0191 0.1306 0.5093
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Entamoeba histolytica cysteine proteinase, putative 0.0191 0.1306 0.5093
Plasmodium falciparum subtilisin-like protease 2 0.0058 0.0223 0.0682
Echinococcus granulosus ubiquitin specific peptidase c family 0.0138 0.0873 0.0873
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0276 0.1993 0.2881
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi hypothetical protein, conserved 0.0281 0.2032 0.2938
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0131 0.0814 0.08
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0412 0.0596
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0036 0.0048 0.0033
Entamoeba histolytica cysteine proteinase 2 0.0191 0.1306 0.5093
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0068 0.0302 0.0364
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0565 0.4335 0.4326
Entamoeba histolytica cysteine protease, putative 0.0081 0.0412 0.1495
Plasmodium vivax GPI-anchor transamidase, putative 0.0064 0.0273 0.0866
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0241 0.1706 0.2748
Echinococcus granulosus neuroendocrine convertase 2 0.0805 0.6275 0.6275
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0081 0.0412 0.1414
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0082 0.0416 0.0402
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0058 0.0223 0.0208
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0081 0.0411 0.1041
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0411 0.0596
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0046 0.0127 0.0112
Schistosoma mansoni calpain-7 (C02 family) 0.0407 0.3057 0.3046
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0104 0.0594 0.0794
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0074 0.0357 0.1276
Loa Loa (eye worm) calpain family protein 1 0.0305 0.2225 0.2215
Echinococcus multilocularis expressed protein 0.0046 0.0127 0.0161
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase BAP1 0.0065 0.0278 0.0278
Brugia malayi Kringle domain containing protein 0.0141 0.0895 0.0878
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Brugia malayi proprotein convertase 2 0.0805 0.6275 0.6268
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0127 0.0109
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0357 0.0484
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0163 0.108 0.1543
Echinococcus multilocularis neuroendocrine convertase 2 0.0805 0.6275 0.7963
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0241 0.1706 0.2748
Loa Loa (eye worm) ubiquitin C-terminal hydrolase UCH-L5 0.0118 0.0712 0.0699
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0182 0.1232 0.1232
Brugia malayi Protein kinase domain containing protein 0.0141 0.0895 0.0878
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0223 0.0283
Echinococcus multilocularis growth factor receptor bound protein 2 0.0272 0.196 0.2487
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0019 0.0005
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0084 0.0435 0.0552
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0081 0.0412 0.0394
Trichomonas vaginalis WD repeat domain, putative 0.0072 0.0338 0.0474
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0081 0.0412 0.1414
Leishmania major small myristoylated protein-3, putative 0.0381 0.284 0.4097
Toxoplasma gondii PAN/Apple domain-containing protein 0.0045 0.0119 0.0319
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0062 0.0256 0.0337
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase isozyme L3, putative 0.0131 0.0814 0.3009
Leishmania major otubain, putative,otubain cysteine peptidase, Clan CA, family C65, putative 0.009 0.0484 0.0632
Plasmodium vivax calpain, putative 0.0348 0.2578 1
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0262 0.1875 0.3028
Schistosoma mansoni lamin 0.0033 0.0019 0.0004
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0412 0.0397
Plasmodium falciparum deubiquinating/deneddylating enzyme 0.0118 0.0712 0.2661
Loa Loa (eye worm) hypothetical protein 0.0064 0.0274 0.0261
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0061 0.0251 0.0237
Entamoeba histolytica protein kinase, putative 0.0088 0.0466 0.1714
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0081 0.0412 0.1042
Trypanosoma brucei calpain-like protein, putative 0.0602 0.4635 0.6752
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0081 0.0412 0.1445
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.1875 0.3028
Loa Loa (eye worm) hypothetical protein 0.0337 0.2483 0.2473
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0046 0.0127 0.0127
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0412 0.0596
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0081 0.0411 0.0411
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0046 0.0127 0.0288
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0876 0.6852 1
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-4 0.0589 0.4525 0.6591
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0221 0.1546 0.2226
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0046 0.0127 0.0351
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0131 0.0814 0.1117
Trypanosoma brucei diphthine synthase, putative 0.0037 0.0055 0.0041
Echinococcus granulosus Peptidase C54 0.0086 0.0452 0.0452
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0083 0.043 0.1489
Loa Loa (eye worm) hypothetical protein 0.0305 0.2225 0.2215
Giardia lamblia Cathepsin B precursor 0.0081 0.0412 0.1042
Echinococcus multilocularis glycoprotein Antigen 5 0.0059 0.0229 0.0291
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0191 0.1306 0.2083
Toxoplasma gondii preprocathepsin c precursor, putative 0.0081 0.0412 0.1495
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0696 0.5393 0.7853
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0241 0.1706 0.2748
Brugia malayi PAN domain containing protein 0.0045 0.0119 0.0101
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0055 0.0202 0.0257
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0082 0.0416 0.1514
Giardia lamblia Cathepsin L precursor 0.0081 0.0412 0.1042
Plasmodium falciparum serine repeat antigen 9 0.0081 0.0412 0.1445
Brugia malayi Trypsin family protein 0.0059 0.0229 0.0211
Onchocerca volvulus 0.0045 0.0119 0.0401
Toxoplasma gondii microneme protein MIC4 0.0045 0.0119 0.0319
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Leishmania major cathepsin L-like protease 0.0342 0.2525 0.3635
Giardia lamblia Cysteine protease 0.0081 0.0412 0.1042
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0189 0.1283 0.1842
Trypanosoma brucei calpain-like protein, putative 0.0348 0.2578 0.3739
Loa Loa (eye worm) prolyl oligopeptidase 0.0182 0.1232 0.1219
Trypanosoma brucei calpain-like protein, putative 0.0328 0.2415 0.3499
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0068 0.0302 0.0404
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0672 0.5201 0.758
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0243 0.1728 0.2493
Echinococcus granulosus lamin dm0 0.0033 0.0019 0.0019
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0081 0.0411 0.0398
Echinococcus granulosus calpain A 0.0328 0.2415 0.2415
Trypanosoma cruzi hypothetical protein, conserved 0.0141 0.0895 0.1273
Trypanosoma cruzi cysteine peptidase, putative 0.049 0.3726 0.5419
Schistosoma mansoni growth factor receptor-bound protein 0.0272 0.196 0.1948
Onchocerca volvulus 0.0342 0.2525 1
Trypanosoma cruzi trypanothione synthetase, putative 0.0071 0.0327 0.044
Giardia lamblia GPI-anchor transamidase, putative 0.0064 0.0273 0.0638
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0065 0.0278 0.0369
Loa Loa (eye worm) hypothetical protein 0.0082 0.0416 0.0403
Loa Loa (eye worm) hypothetical protein 0.0046 0.0127 0.0114
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0081 0.0411 0.1443
Brugia malayi Cathepsin L-like precursor 0.0232 0.1631 0.1615
Schistosoma mansoni Mername-AA248 (C02 family) 0.0328 0.2415 0.2403
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.1875 0.3028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0412 0.0596
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0281 0.2032 0.2938
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0109 0.0635 0.0635
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0327 0.2408 0.3489
Entamoeba histolytica cysteine protease, putative 0.0081 0.0412 0.1495
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Loa Loa (eye worm) hypothetical protein 0.0047 0.0134 0.0121
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Echinococcus granulosus GPI anchor transamidase 0.0064 0.0273 0.0273
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0191 0.1306 0.1293
Brugia malayi neuroendocrine convertase 1 precursor 0.0805 0.6275 0.6268
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0046 0.0127 0.0161
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0381 0.284 0.4122
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Giardia lamblia Cysteine protease 0.0081 0.0412 0.1042
Loa Loa (eye worm) trypsin family protein 0.0059 0.0229 0.0216
Schistosoma mansoni diphthine synthase 0.0037 0.0055 0.004
Plasmodium falciparum serine repeat antigen 7 0.0081 0.0412 0.1445
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0046 0.0127 0.0161
Giardia lamblia Cathepsin L-like protease 0.0081 0.0412 0.1042
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0342 0.2525 1
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Brugia malayi cathepsin L-like precursor 0.0232 0.1631 0.1615
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0638 0.4929 0.7171
Schistosoma mansoni hypothetical protein 0.0049 0.0156 0.0141
Echinococcus multilocularis calpain 7 (C02 family) 0.0361 0.2684 0.3406
Brugia malayi cathepsin Z-like cysteine proteinase 0.0081 0.0412 0.0394
Trypanosoma cruzi trypanothione synthetase, putative 0.0071 0.0327 0.044
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0138 0.0873 0.3351
Trypanosoma cruzi cysteine peptidase, Clan CA, family C54, putative 0.0205 0.1416 0.2036
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0059 0.0229 0.0211
Leishmania major PFPI/DJ-1-like protein, putative 0.0473 0.3589 0.52
Onchocerca volvulus 0.0049 0.0156 0.0546
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0271 0.1954 0.2824
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0131 0.0814 0.1265
Onchocerca volvulus 0.0049 0.0156 0.0546
Echinococcus multilocularis cathepsin b 0.0565 0.4335 0.5501
Onchocerca volvulus 0.0059 0.0229 0.084
Leishmania major hypothetical protein, conserved 0.0281 0.2032 0.2909
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0081 0.0412 0.0596
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0081 0.0412 0.1414
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0068 0.0302 0.0302
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.009 0.0484 0.0671
Plasmodium falciparum subtilisin-like protease 3 0.0058 0.0223 0.0682
Schistosoma mansoni cathepsin s 0.011 0.0649 0.0635
Loa Loa (eye worm) ctsf protein 0.0342 0.2525 0.2515
Leishmania major small myristoylated protein 4, putative 0.0652 0.5043 0.7338
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Toxoplasma gondii ubiquitin-specific protease USP4 0.0046 0.0127 0.0351
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0076 0.0372 0.0531
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0182 0.1232 0.1563
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0127 0.0109
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0272 0.196 0.1949
Toxoplasma gondii subtilisin SUB9 0.0058 0.0223 0.0737
Onchocerca volvulus Cathepsin L homolog 0.0081 0.0412 0.1567
Loa Loa (eye worm) hypothetical protein 0.0046 0.0127 0.0114
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0109 0.0635 0.0622
Onchocerca volvulus 0.0064 0.0274 0.1019
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0438 0.3306 0.4784
Brugia malayi hypothetical protein 0.0046 0.0127 0.0109
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0138 0.0873 0.124
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Giardia lamblia Cathepsin L precursor 0.0081 0.0412 0.1042
Plasmodium falciparum cysteine proteinase falcipain 1 0.0191 0.1306 0.5064
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0118 0.0712 0.1005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0086 0.0452 0.0663
Echinococcus granulosus furin 0.1264 1 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi otubain cysteine peptidase, Clan CA, family C65, putative 0.009 0.0484 0.0671
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0068 0.0302 0.0404
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0046 0.0127 0.0351
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0522 0.3983 0.5796
Brugia malayi PAN domain containing protein 0.0045 0.0119 0.0101
Onchocerca volvulus 0.0059 0.0235 0.0865
Trypanosoma cruzi cysteine peptidase inhibitor, putative 0.0245 0.1742 0.2514
Loa Loa (eye worm) hypothetical protein 0.0045 0.0119 0.0105
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0262 0.1875 0.3028
Giardia lamblia Cathepsin B precursor 0.0081 0.0412 0.1042
Trichomonas vaginalis Clan CA, family C12, ubiquitin hydrolase-like cysteine peptidase 0.0131 0.0814 0.1265
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0223 0.0283
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0109 0.0635 0.0854
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0081 0.0412 0.0398
Trichomonas vaginalis AGC family protein kinase 0.0038 0.0059 0.001
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0281 0.2032 0.2938
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0046 0.0127 0.0112
Echinococcus multilocularis cathepsin L cysteine protease 0.0342 0.2525 0.3205
Toxoplasma gondii microneme protein MIC17C 0.0045 0.0119 0.0319
Brugia malayi Cathepsin L-like cysteine proteinase 0.0232 0.1631 0.1615
Echinococcus multilocularis protein will die slowly 0.0072 0.0338 0.0429
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0342 0.2525 0.411
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Leishmania major small myristoylated protein-1 0.0438 0.3302 0.4777
Schistosoma mansoni cathepsin B (C01 family) 0.0081 0.0412 0.0397
Schistosoma mansoni site-1 peptidase (S08 family) 0.0058 0.0223 0.0208
Leishmania major ubiquitin carboxyl-terminal hydrolase, putative,cysteine peptidase, Clan CA, family C12, putative 0.0118 0.0712 0.0967
Leishmania major META domain containing protein 0.0281 0.2032 0.2909
Onchocerca volvulus 0.0232 0.1631 0.6433
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0046 0.0127 0.0161
Toxoplasma gondii subtilisin SUB7 0.0058 0.0223 0.0737
Loa Loa (eye worm) hypothetical protein 0.0565 0.4335 0.4327
Loa Loa (eye worm) hypothetical protein 0.0081 0.0412 0.0398
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0357 0.1198
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0229 0.0214
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0068 0.0302 0.0404
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0104 0.0594 0.09
Loa Loa (eye worm) hypothetical protein 0.011 0.0649 0.0636
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0876 0.6852 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.1631 0.2624
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0079 0.0395 0.0395
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0342 0.2525 0.411
Plasmodium falciparum serine repeat antigen 2 0.0081 0.0412 0.1445
Brugia malayi PAN domain containing protein 0.0045 0.0119 0.0101
Trichomonas vaginalis AGC family protein kinase 0.0038 0.0059 0.001
Schistosoma mansoni cathepsin F (C01 family) 0.0342 0.2525 0.2514
Loa Loa (eye worm) calpain D 0.0313 0.2289 0.2279
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0081 0.0412 0.1414
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0281 0.2032 0.2938
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0127 0.0288
Brugia malayi calpain 5 0.0087 0.0464 0.0446
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0061 0.0251 0.0319
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Echinococcus granulosus transmembrane protease serine 3 0.0059 0.0229 0.0229
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0084 0.0435 0.1588
Mycobacterium ulcerans hypothetical protein 0.0104 0.0596 1
Loa Loa (eye worm) hypothetical protein 0.0485 0.3687 0.3678
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0342 0.2525 0.411
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0191 0.1306 0.1874
Echinococcus multilocularis Furin 1 0.0319 0.2343 0.2973
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0081 0.0411 0.0596
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.049 0.3726 0.5419
Brugia malayi Muscle positioning protein 4 0.0059 0.0235 0.0217
Onchocerca volvulus 0.0045 0.0119 0.0401
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Schistosoma mansoni hypothetical protein 0.0433 0.3265 0.3255
Onchocerca volvulus Legumain homolog 0.0037 0.0053 0.0137
Echinococcus granulosus cathepsin L 0.0191 0.1306 0.1306
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0292 0.2118 0.3064
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0131 0.0814 0.1154
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0522 0.3983 0.5796
Leishmania major cysteine peptidase A (CPA) 0.0342 0.2525 0.3635
Toxoplasma gondii microneme protein MIC17B 0.0045 0.0119 0.0319
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0119 0.0319
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0526 0.4015 0.5844
Trypanosoma cruzi hypothetical protein, conserved 0.035 0.2593 0.376
Giardia lamblia Encystation-specific protease 0.0081 0.0412 0.1042
Loa Loa (eye worm) WD40 repeat protein 0.0072 0.0338 0.0324
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Loa Loa (eye worm) hypothetical protein 0.0059 0.0229 0.0216
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0876 0.6852 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0069 0.031 0.0428
Leishmania major hypothetical protein, conserved 0.035 0.2593 0.3734
Echinococcus granulosus intermediate filament protein 0.0033 0.0019 0.0019
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0163 0.108 0.1543
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Echinococcus granulosus cathepsin L cysteine proteinase 0.0342 0.2525 0.2525
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0046 0.0127 0.0161
Echinococcus multilocularis 0.1003 0.788 1
Schistosoma mansoni furin-1 (S08 family) 0.0543 0.4155 0.4146
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0074 0.0357 0.0453
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0602 0.4635 0.6752
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0876 0.6852 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0081 0.0412 0.1042
Brugia malayi Protein kinase domain containing protein 0.0038 0.0059 0.004
Schistosoma mansoni cathepsin F (C01 family) 0.0342 0.2525 0.2514
Brugia malayi Papain family cysteine protease containing protein 0.0191 0.1306 0.129
Leishmania major cathepsin L-like protease 0.049 0.3726 0.54
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0059 0.0229 0.0229
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.035 0.2589 0.2578
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0086 0.0452 0.0663
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0221 0.1546 0.2226
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0064 0.027 0.0358
Echinococcus granulosus dnaJ subfamily B 0.0433 0.3265 0.3265
Entamoeba histolytica cysteine protease, putative 0.0081 0.0412 0.1495
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0565 0.4335 0.6312
Brugia malayi Cathepsin L-like precursor 0.0342 0.2525 0.2511
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0281 0.2032 0.2938
Loa Loa (eye worm) hypothetical protein 0.0049 0.0156 0.0142
Loa Loa (eye worm) hypothetical protein 0.0046 0.0127 0.0114
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) 0.0058 0.0223 0.5
Plasmodium falciparum cysteine proteinase falcipain 3 0.0342 0.2525 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Toxoplasma gondii kringle domain-containing protein 0.0141 0.0895 0.3442
Leishmania major cathepsin L-like protease 0.0342 0.2525 0.3635
Schistosoma mansoni hypothetical protein 0.0141 0.0895 0.0882
Brugia malayi Cathepsin L-like precursor 0.0342 0.2525 0.2511
Leishmania major hypothetical protein, unknown function 0.0704 0.546 0.7953
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0174 0.1165 0.1668
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0163 0.108 0.4183
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0051 0.0166 0.0453
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0046 0.0127 0.0351
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0672 0.5201 0.757
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0189 0.1283 0.1808
Brugia malayi cathepsin L precursor 0.0081 0.0412 0.0394
Plasmodium vivax unspecified product 0.011 0.0649 0.2355
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0223 0.0283
Onchocerca volvulus 0.0045 0.0119 0.0401
Echinococcus multilocularis cathepsin b 0.0565 0.4335 0.5501
Trichomonas vaginalis hypothetical protein 0.0241 0.1706 0.2748
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0397 0.2972 0.2962
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0412 0.0394
Leishmania major hypothetical protein, conserved 0.0281 0.2032 0.2909
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0081 0.0412 0.1445
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0082 0.0416 0.0604
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.046 0.3482 0.5063
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0438 0.3306 0.4784
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0068 0.0302 0.0383
Schistosoma mansoni tyrosine kinase 0.0264 0.1898 0.1886
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0061 0.0247 0.0834
Mycobacterium tuberculosis Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) 0.0058 0.0223 0.5
Brugia malayi calpain family protein 1 0.0392 0.2934 0.2921
Giardia lamblia Cathepsin B precursor 0.0081 0.0412 0.1042
Leishmania major receptor-type adenylate cyclase a-like protein 0.0281 0.2032 0.2909
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0276 0.1988 0.2844
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0081 0.0412 0.1042
Loa Loa (eye worm) hypothetical protein 0.009 0.0484 0.0471
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0276 0.1988 0.3217
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0058 0.0223 0.0205
Loa Loa (eye worm) hypothetical protein 0.0081 0.0412 0.0398
Brugia malayi Trypsin family protein 0.0337 0.2483 0.2469
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0055 0.0202 0.0184
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.1264 1 1
Onchocerca volvulus 0.0342 0.2525 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0109 0.0635 0.0892
Schistosoma mansoni cathepsin F (C01 family) 0.0232 0.1631 0.1618
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0319 0.2343 0.2331
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0082 0.0416 0.0416
Giardia lamblia Hypothetical protein 0.0051 0.0166 0.0327
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Echinococcus granulosus ubiquitin specific protease 41 0.0082 0.0416 0.0416
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0119 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0607 0.4677 0.6814
Echinococcus granulosus lamin 0.0033 0.0019 0.0019
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0292 0.2118 0.3064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0342 0.2525 0.411
Toxoplasma gondii autophagy-related cysteine peptidase atg4, putative 0.0048 0.0146 0.0426
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0831 0.6486 0.9461
Entamoeba histolytica cysteine proteinase, putative 0.0191 0.1306 0.5093
Echinococcus multilocularis calpain A 0.0397 0.2972 0.3772
Echinococcus multilocularis ubiquitin specific protease 41 0.0082 0.0416 0.0528
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0082 0.0416 0.0416
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0243 0.1728 0.2461
Echinococcus multilocularis PAB dependent poly(A) specific ribonuclease 0.0032 0.0015 0.0019
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0319 0.2343 0.3807
Schistosoma mansoni site-1 peptidase (S08 family) 0.0058 0.0223 0.0208
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0412 0.0397
Echinococcus granulosus epidermal growth factor receptor 0.0264 0.1898 0.1898
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0081 0.0412 0.0397
Trypanosoma brucei small myristoylated protein 1-2 0.0438 0.3302 0.4799
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Onchocerca volvulus 0.0059 0.0229 0.084
Plasmodium falciparum cysteine protease ATG4, putative 0.0048 0.0146 0.0369
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0191 0.1306 0.2083
Toxoplasma gondii subtilisin SUB11 0.0058 0.0223 0.0737
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0046 0.0127 0.0351
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0061 0.0251 0.033
Loa Loa (eye worm) hypothetical protein 0.0041 0.0088 0.0075
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0104 0.0594 0.0577
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0082 0.0416 0.1056
Leishmania major GPI-anchor transamidase subunit 8 (GPI8), putative 0.0064 0.0273 0.0321
Loa Loa (eye worm) hypothetical protein 0.011 0.0649 0.0636
Brugia malayi Papain family cysteine protease containing protein 0.0342 0.2525 0.2511
Loa Loa (eye worm) hypothetical protein 0.0037 0.0058 0.0044
Plasmodium vivax ubiquitin C-terminal hydrolase, family 1, putative 0.0118 0.0712 0.2605
Trichomonas vaginalis conserved hypothetical protein 0.0241 0.1706 0.2748
Echinococcus granulosus cysteine protease atg4b 0.0086 0.0452 0.0452
Leishmania major trypanothione synthetase, putative 0.0071 0.0327 0.0401
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0342 0.2525 0.411
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0327 0.2408 0.3489
Schistosoma mansoni hemoglobinase (C13 family) 0.0037 0.0053 0.0038
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0565 0.4335 0.4326
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0638 0.4929 0.7182
Schistosoma mansoni hypothetical protein 0.0072 0.0338 0.0323
Trypanosoma brucei calpain, putative 0.0515 0.3926 0.5713
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0412 0.0596
Echinococcus multilocularis calpain 0.0328 0.2415 0.3065
Schistosoma mansoni ubiquitinyl hydrolase-BAP1 (C12 family) 0.0065 0.0278 0.0263
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0229 0.0214
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0046 0.0127 0.0127
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0342 0.2525 0.411
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0076 0.0372 0.0358
Onchocerca volvulus 0.0278 0.2009 0.794
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.049 0.3726 0.5419
Onchocerca volvulus 0.0342 0.2525 1
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0082 0.0416 0.0571
Trypanosoma brucei conserved protein 0.0225 0.1581 0.2278
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Onchocerca volvulus 0.0045 0.0119 0.0401
Loa Loa (eye worm) cathepsin B 0.0276 0.1988 0.1977
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0274 0.1975 0.2855
Trypanosoma brucei inhibitor of cysteine peptidase 0.0245 0.1742 0.2514
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0051 0.0166 0.0153
Echinococcus granulosus diphthine synthase 0.0037 0.0055 0.0055
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0082 0.0416 0.0571
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0131 0.0814 0.08
Leishmania major kinesin, putative 0.0087 0.0464 0.0602
Echinococcus multilocularis hypothetical protein 0.0328 0.2415 0.3065
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0081 0.0411 0.1412
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0243 0.1728 0.2493
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma brucei Calpain-like protein CALP1.3 0.0522 0.3983 0.5796
Entamoeba histolytica peptidase, C54 family 0.0048 0.0146 0.0426
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Loa Loa (eye worm) hypothetical protein 0.0037 0.0055 0.0041
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0274 0.1975 0.2855
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0138 0.0873 0.0859
Entamoeba histolytica calpain family cysteine protease, putative 0.0313 0.2289 0.9051
Plasmodium vivax subtilisin-like protease 2, putative 0.0058 0.0223 0.0668
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0082 0.0416 0.0571
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0061 0.0251 0.033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0372 0.2773 0.4024
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0109 0.0635 0.0892
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.1875 0.3028
Entamoeba histolytica GPI-anchor transamidase, putative 0.0064 0.0273 0.0938
Brugia malayi Papain family cysteine protease containing protein 0.0191 0.1306 0.129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0779 0.6068 0.77
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0081 0.0412 0.0397
Trypanosoma cruzi cysteine peptidase, putative 0.011 0.0649 0.0912
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0342 0.2525 0.411
Brugia malayi hypothetical protein 0.0059 0.0229 0.0211
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.038 0.2831 0.4109
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0412 0.0394
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0051 0.0166 0.0152
Loa Loa (eye worm) TK/EGFR protein kinase 0.0264 0.1898 0.1887
Loa Loa (eye worm) hypothetical protein 0.0045 0.0119 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Loa Loa (eye worm) hypothetical protein 0.0033 0.0019 0.0005
Schistosoma mansoni hypothetical protein 0.0041 0.0088 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0327 0.044
Trypanosoma brucei trypanothione synthetase, putative 0.0071 0.0327 0.044
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0357 0.0484
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0109 0.0635 0.0618
Onchocerca volvulus 0.0049 0.0156 0.0546
Trypanosoma cruzi hypothetical protein, conserved 0.0281 0.2032 0.2938
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0342 0.2525 0.411
Schistosoma mansoni intermediate filament proteins 0.0033 0.0019 0.0004
Schistosoma mansoni calpain-2 (C02 family) 0.0241 0.1706 0.1693
Trypanosoma brucei GPI-anchor transamidase subunit 8 (GPI8) 0.0064 0.0273 0.0362
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0638 0.4929 0.7182
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0082 0.0416 0.0398
Brugia malayi celfurPC protein 0.1003 0.788 0.7876
Toxoplasma gondii diphthine synthase, putative 0.0037 0.0055 0.0059
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0086 0.0452 0.0584
Echinococcus granulosus tissue type plasminogen activator 0.0141 0.0895 0.0895
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Brugia malayi Will die slowly protein 0.0072 0.0338 0.032
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0046 0.0127 0.0112
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0327 0.2408 0.3489
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0119 0.0105
Giardia lamblia Cathepsin L precursor 0.0081 0.0412 0.1042
Trypanosoma cruzi cruzipain precursor, putative 0.011 0.0649 0.0912
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0084 0.0435 0.0598
Mycobacterium leprae Possible secreted protease 0.0058 0.0223 0.5
Loa Loa (eye worm) proprotein convertase 2 0.0319 0.2343 0.2332
Trypanosoma brucei otubain cysteine peptidase, Clan CA, family C65, putative 0.009 0.0484 0.0671
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0412 0.0397
Plasmodium falciparum serine repeat antigen 3 0.0081 0.0412 0.1445
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0602 0.4635 0.6752
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.1875 0.3028
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Schistosoma mansoni glycosylphosphatidylinositol:protein transamidase (C13 family) 0.0064 0.0273 0.0258
Onchocerca volvulus 0.0342 0.2525 1
Plasmodium falciparum serine repeat antigen 6 0.0081 0.0412 0.1445
Trypanosoma brucei META domain/Domain of unknown function (DUF1935), putative 0.0281 0.2032 0.2938
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0046 0.0127 0.0161
Echinococcus multilocularis GPI anchor transamidase 0.0064 0.0273 0.0347
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0223 0.0283
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0074 0.0357 0.1224
Trypanosoma brucei kinesin, putative 0.0087 0.0464 0.0641
Trichomonas vaginalis ubiquitin specific protease, putative 0.0066 0.0291 0.0396
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0046 0.0127 0.0112
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0051 0.0166 0.0166
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0058 0.0223 0.0283
Loa Loa (eye worm) hypothetical protein 0.0059 0.0229 0.0216
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0191 0.1306 0.1293
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0397 0.2972 0.2962
Onchocerca volvulus 0.0045 0.0119 0.0401
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0081 0.0412 0.0596
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0051 0.0166 0.0153
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Onchocerca volvulus 0.0046 0.0127 0.0433
Trypanosoma brucei cysteine peptidase, Clan CA, family C51, putative 0.0327 0.2408 0.3489
Trypanosoma cruzi major cysteine proteinase, putative 0.0229 0.1612 0.2323
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Echinococcus multilocularis cysteine protease 0.0342 0.2525 0.3205
Loa Loa (eye worm) peptidase C13 family protein 0.0037 0.0053 0.0039
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0086 0.0452 0.0663
Onchocerca volvulus 0.0045 0.0119 0.0401
Echinococcus multilocularis cysteine protease 0.0342 0.2525 0.3205
Brugia malayi PAN domain containing protein 0.0045 0.0119 0.0101
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0372 0.0507
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0046 0.0127 0.0114
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0076 0.0372 0.0355
Mycobacterium tuberculosis Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) 0.0058 0.0223 0.5
Brugia malayi PAN domain containing protein 0.0045 0.0119 0.0101
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0046 0.0127 0.0127
Trypanosoma brucei SUMO1/Ulp2, putative 0.0189 0.1283 0.1842
Entamoeba histolytica cysteine protease inhibitor 1 (EhICP1) 0.0245 0.1742 0.6848
Brugia malayi Trypsin family protein 0.0059 0.0229 0.0211
Echinococcus granulosus Ubiquitin thioesterase otubain protein 0.009 0.0484 0.0484
Trypanosoma cruzi trypanothione synthetase 0.0071 0.0327 0.044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0602 0.4635 0.6752
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Onchocerca volvulus 0.0045 0.0119 0.0401
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0068 0.0302 0.0383
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0068 0.0302 0.0284
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0046 0.0127 0.0112
Mycobacterium tuberculosis Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) 0.0058 0.0223 0.5
Onchocerca volvulus 0.0059 0.0229 0.084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0232 0.1631 0.2624
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0141 0.0895 0.3331
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Plasmodium vivax vivapain-2 0.0342 0.2525 0.979
Trypanosoma cruzi Domain of unknown function (DUF1935), putative 0.0281 0.2032 0.2938
Onchocerca volvulus Cathepsin L homolog 0.0342 0.2525 1
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0035 0.004 0.0026
Loa Loa (eye worm) hypothetical protein 0.0081 0.0412 0.0398
Toxoplasma gondii exonuclease 0.0064 0.027 0.0928
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0342 0.2525 0.3205
Brugia malayi Furin-like cysteine rich region family protein 0.0264 0.1898 0.1883
Onchocerca volvulus 0.0045 0.0119 0.0401
Loa Loa (eye worm) hypothetical protein 0.0074 0.0357 0.0344
Plasmodium falciparum GPI-anchor transamidase, putative 0.0064 0.0273 0.0884
Echinococcus granulosus growth factor receptor bound protein 2 0.0272 0.196 0.196
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0221 0.1546 0.2226
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0051 0.0166 0.0153
Echinococcus granulosus calpain A 0.0397 0.2972 0.2972
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Echinococcus multilocularis Peptidase C54 0.0086 0.0452 0.0573
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0104 0.0594 0.0754
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0127 0.0109
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0163 0.108 0.1543
Trypanosoma cruzi conserved protein 0.0466 0.3533 0.5137
Trichomonas vaginalis AGC family protein kinase 0.0038 0.0059 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0281 0.2032 0.2938
Loa Loa (eye worm) calpain 5 0.0087 0.0464 0.0451
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0081 0.0412 0.0596
Onchocerca volvulus 0.0045 0.0119 0.0401
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0191 0.1306 0.1874
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0046 0.0127 0.0114
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0081 0.0412 0.0397
Brugia malayi Trypsin-like protease protein 5 0.0059 0.0229 0.0211
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0061 0.0251 0.033
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0526 0.4015 0.5844
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0635 0.4901 0.7141
Loa Loa (eye worm) hypothetical protein 0.0342 0.2525 0.2515
Trypanosoma cruzi trypanothione synthetase-like protein, putative 0.0071 0.0327 0.044
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0607 0.4677 0.6814
Entamoeba histolytica protein kinase, putative 0.0038 0.0059 0.0075
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0068 0.0302 0.0414
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0223 0.0283
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0319 0.2343 0.3807
Trypanosoma cruzi cysteine peptidase, Clan CD, family C13, putative 0.0064 0.0273 0.0362
Trichomonas vaginalis AGC family protein kinase 0.0038 0.0059 0.001
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0189 0.1283 0.1842
Toxoplasma gondii cathepsin B 0.0276 0.1988 0.7838
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0876 0.6852 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0118 0.0712 0.0904
Loa Loa (eye worm) hypothetical protein 0.0045 0.0119 0.0105
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0081 0.0412 0.1445
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Echinococcus granulosus calpain 7 C02 family 0.0361 0.2684 0.2684
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0119 0.0319
Trypanosoma cruzi subtilisin peptidase 0.0058 0.0223 0.0288
Trypanosoma brucei cysteine peptidase, Clan CA, family C54, putative 0.0205 0.1416 0.2036
Trypanosoma brucei unspecified product 0.0281 0.2032 0.2938
Brugia malayi Cathepsin L-like precursor 0.0342 0.2525 0.2511
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0046 0.0127 0.0351
Schistosoma mansoni family C13 non-peptidase homologue (C13 family) 0.0037 0.0053 0.0038
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0397 0.2972 0.3772
Trypanosoma cruzi cruzipain precursor, putative 0.049 0.3726 0.5419
Plasmodium falciparum ubiquitin specific protease, putative 0.0046 0.0127 0.0294
Echinococcus multilocularis enteropeptidase 0.0059 0.0229 0.0291
Trypanosoma cruzi subtilisin-like serine peptidase, putative 0.0062 0.0256 0.0337
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0061 0.0251 0.0289
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0051 0.0166 0.0166
Leishmania major subtilisin-like serine peptidase 0.0058 0.0223 0.0248
Loa Loa (eye worm) subtilase 0.0058 0.0223 0.021
Trypanosoma cruzi cysteine proteinase, putative 0.0191 0.1306 0.1874
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0046 0.0127 0.0161
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0059 0.0229 0.0229
Mycobacterium leprae PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) 0.0058 0.0223 0.5
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0051 0.0166 0.0148
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase UCHL3 0.0131 0.0814 0.3115
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0127 0.0109
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0082 0.0416 0.0532
Schistosoma mansoni hypothetical protein 0.0046 0.0127 0.0112
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0704 0.546 0.7953
Schistosoma mansoni hypothetical protein 0.0059 0.0229 0.0214
Brugia malayi calpain family protein 1 0.0392 0.2934 0.2921
Trypanosoma brucei trypanothione synthetase 0.0071 0.0327 0.044
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0342 0.2525 0.411
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0276 0.1988 0.2874
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0063 0.0262 0.0248
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Echinococcus multilocularis calpain family protein 1, d 0.0305 0.2225 0.2824
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0046 0.0127 0.0351
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma brucei pyroglutamyl-peptidase I, putative 0.0451 0.3408 0.4954
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.049 0.3726 0.5419
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0274 0.1975 0.2855
Loa Loa (eye worm) hypothetical protein 0.0081 0.0412 0.0398
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0074 0.0357 0.0339
Brugia malayi Trypsin family protein 0.0059 0.0229 0.0211
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0229 0.0214
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0381 0.284 0.4122
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0051 0.0166 0.0189
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0271 0.1954 0.2794
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0522 0.3983 0.5796
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.1875 0.3028
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0672 0.5201 0.758
Trypanosoma cruzi hypothetical protein, conserved 0.0281 0.2032 0.2938
Onchocerca volvulus 0.0046 0.0127 0.0433
Trypanosoma cruzi unspecified product 0.0438 0.3302 0.4799
Brugia malayi SEA domain containing protein 0.0049 0.0156 0.0137
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0348 0.2578 0.3739
Trypanosoma cruzi cysteine peptidase, putative 0.0342 0.2525 0.3661
Plasmodium vivax vivapain-2 0.0342 0.2525 0.979
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0081 0.0412 0.1042
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0127 0.0109
Mycobacterium leprae PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) 0.0058 0.0223 0.5
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0059 0.0229 0.0291
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0081 0.0412 0.1495
Loa Loa (eye worm) hypothetical protein 0.0058 0.0223 0.021
Brugia malayi Cathepsin L-like precursor 0.0342 0.2525 0.2511
Loa Loa (eye worm) AGC/AKT protein kinase 0.0038 0.0059 0.0045
Toxoplasma gondii hypothetical protein 0.0045 0.0119 0.0319
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0119 0.0319
Loa Loa (eye worm) hypothetical protein 0.0081 0.0412 0.0398
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0046 0.0127 0.0112
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0074 0.0357 0.0342
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0046 0.0127 0.0127
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Entamoeba histolytica cysteine proteinase, putative 0.0191 0.1306 0.5093
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0342 0.2525 1
Echinococcus multilocularis lamin 0.0033 0.0019 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Toxoplasma gondii subtilisin SUB4 0.0058 0.0223 0.0737
Echinococcus granulosus calpain 0.0328 0.2415 0.2415
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0088 0.007
Leishmania major hypothetical protein, conserved 0.0281 0.2032 0.2909
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0081 0.0412 0.1414
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0081 0.0412 0.0596
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0118 0.0712 0.0712
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0138 0.0873 0.1363
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0119 0.0319
Brugia malayi prolyl oligopeptidase family protein 0.0182 0.1232 0.1215
Schistosoma mansoni autophagin-1 (C54 family) 0.0086 0.0452 0.0437
Entamoeba histolytica cysteine proteinase, putative 0.0191 0.1306 0.5093
Loa Loa (eye worm) hypothetical protein 0.0232 0.1631 0.162
Plasmodium vivax ubiquitin specific protease, putative 0.0046 0.0127 0.0288
Entamoeba histolytica cysteine proteinase, putative 0.0342 0.2525 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0202 0.0188
Loa Loa (eye worm) hypothetical protein 0.0141 0.0895 0.0883
Brugia malayi cathepsin F-like cysteine proteinase 0.011 0.0649 0.0632
Onchocerca volvulus 0.0046 0.0127 0.0433
Entamoeba histolytica peptidase, C54 family 0.0048 0.0146 0.0426
Brugia malayi prolyl oligopeptidase family protein 0.0061 0.0251 0.0233
Plasmodium falciparum serine repeat antigen 8 0.0081 0.0412 0.1445
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0342 0.2525 0.411
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0068 0.0302 0.0414
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.046 0.3482 0.5042
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Schistosoma mansoni calpain-7 (C02 family) 0.0407 0.3057 0.3046
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Plasmodium vivax unspecified product 0.0081 0.0412 0.1414
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0082 0.0416 0.0402
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0104 0.0594 0.0832
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0081 0.0412 0.0398
Schistosoma mansoni calpain C (C02 family) 0.0328 0.2415 0.2403
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0243 0.1728 0.2493
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0064 0.0273 0.0366
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi serine peptidase, clan SB, family S8-like protein 0.0058 0.0223 0.0288
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0138 0.0873 0.1107
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0104 0.0594 0.0832
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0602 0.4635 0.6752
Loa Loa (eye worm) hypothetical protein 0.0059 0.0229 0.0216
Brugia malayi Cathepsin L-like precursor 0.0342 0.2525 0.2511
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0412 0.0596
Echinococcus multilocularis cysteine protease atg4b 0.0086 0.0452 0.0573
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0119 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0051 0.0166 0.0189
Loa Loa (eye worm) hypothetical protein 0.006 0.0243 0.0229
Trypanosoma cruzi glutathionylspermidine synthase, putative 0.0071 0.0327 0.044
Onchocerca volvulus Cathepsin L homolog 0.0342 0.2525 1
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0243 0.1728 0.2461
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0118 0.0712 0.0904
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Echinococcus multilocularis Mastin 0.0059 0.0229 0.0291
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0229 0.0214
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0241 0.1706 0.2748
Toxoplasma gondii microneme protein MIC17A 0.0045 0.0119 0.0319
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0319 0.2343 0.3807
Trypanosoma brucei subtilisin peptidase 0.0058 0.0223 0.0288
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0348 0.2578 0.3739
Loa Loa (eye worm) hypothetical protein 0.0131 0.0814 0.0801
Schistosoma mansoni hypothetical protein 0.0262 0.1875 0.1862
Echinococcus multilocularis membrane bound transcription factor site 1 0.0058 0.0223 0.0283
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0086 0.0452 0.0437
Trichomonas vaginalis ubiquitin specific protease, putative 0.0046 0.0127 0.0123
Brugia malayi Cathepsin L-like precursor 0.0232 0.1631 0.1615
Echinococcus granulosus PAB dependent polyA specific ribonuclease 0.0032 0.0015 0.0015
Plasmodium falciparum cysteine repeat modular protein 1 0.0141 0.0895 0.3403
Entamoeba histolytica cysteine protease, putative 0.0081 0.0412 0.1495
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0243 0.0224
Entamoeba histolytica diphthine synthase, putative 0.0037 0.0055 0.0059
Loa Loa (eye worm) hypothetical protein 0.0045 0.0119 0.0105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0058 0.0223 0.0223
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.1264 1 1
Onchocerca volvulus 0.0045 0.0119 0.0401
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0243 0.1728 0.2493
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase, family 1 protein 0.0118 0.0712 0.2704
Giardia lamblia Cysteine protease 0.0081 0.0412 0.1042
Schistosoma mansoni hemoglobinase (C13 family) 0.0037 0.0053 0.0038
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0046 0.0127 0.0127
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0607 0.4677 0.6814
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0412 0.0596
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase isozyme 0.0131 0.0814 0.1033
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0061 0.0247 0.0323
Plasmodium vivax serine-repeat antigen (SERA) 0.0081 0.0412 0.1414
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0058 0.0223 0.0208
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0051 0.0166 0.0148
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0381 0.284 0.4122
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0138 0.0873 0.124
Leishmania major cathepsin L-like protease 0.0342 0.2525 0.3635
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Brugia malayi calpain 5 0.0241 0.1706 0.169
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0081 0.0412 0.1414
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0081 0.0412 0.1414
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0392 0.2934 0.2924
Onchocerca volvulus 0.0337 0.2483 0.9832
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0652 0.5043 0.7349
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0045 0.0119 0.0319
Entamoeba histolytica hypothetical protein 0.0065 0.0278 0.0958
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Trypanosoma cruzi cysteine protease, putative 0.0191 0.1306 0.1874
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0059 0.0229 0.0214
Entamoeba histolytica hypothetical protein 0.0046 0.0127 0.0351
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0221 0.1546 0.2194
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0138 0.0873 0.124
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0081 0.0412 0.1414
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0274 0.1975 0.2855
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0081 0.0412 0.1414
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0202 0.0188
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.049 0.3726 0.5419
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0081 0.0412 0.0596
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0055 0.0202 0.0189
Echinococcus granulosus cathepsin L 0.0081 0.0412 0.0412
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0229 0.0214
Echinococcus granulosus calpain 5 0.0328 0.2415 0.2415
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.1875 0.3028
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0104 0.0594 0.0594
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0118 0.0712 0.1005
Loa Loa (eye worm) hypothetical protein 0.0046 0.0127 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.1875 0.3028
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0876 0.6852 1
Brugia malayi Cathepsin L-like precursor 0.011 0.0649 0.0632
Plasmodium vivax subtilisin-like serine protease, putative 0.0058 0.0223 0.0668
Plasmodium falciparum serine repeat antigen 5 0.0081 0.0412 0.1445
Onchocerca volvulus 0.0059 0.0229 0.084
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0831 0.6486 0.9461
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0119 0.0319
Toxoplasma gondii subtilisin SUB12 0.0103 0.0587 0.2203
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0229 0.0214
Onchocerca volvulus 0.0342 0.2525 1
Echinococcus granulosus glycoprotein Antigen 5 0.0059 0.0229 0.0229
Onchocerca volvulus 0.0083 0.0424 0.1617
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0229 0.0214
Echinococcus granulosus cathepsin b 0.0565 0.4335 0.4335
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0046 0.0127 0.0127
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0086 0.0452 0.0663
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0131 0.0814 0.1154
Trichomonas vaginalis AGC family protein kinase 0.0038 0.0059 0.001
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.049 0.3726 0.5419
Onchocerca volvulus 0.0058 0.0223 0.0816
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0081 0.0412 0.1495
Echinococcus multilocularis cathepsin L 0.0191 0.1306 0.1657
Trichomonas vaginalis hypothetical protein 0.0262 0.1875 0.3028
Entamoeba histolytica cysteine proteinase, putative 0.0342 0.2525 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0381 0.284 0.4122
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0046 0.0127 0.0351
Trypanosoma brucei small myristoylated protein 1-1 0.0438 0.3302 0.4799
Schistosoma mansoni family C12 unassigned peptidase (C12 family) 0.0131 0.0814 0.08
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0046 0.0127 0.0161
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0229 0.0214
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Leishmania major hypothetical protein, conserved,calpain-like cysteine peptidase, Clan CA, family C2 0.0589 0.4525 0.6577
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0243 0.1728 0.2493
Onchocerca volvulus Cathepsin F homolog 0.0342 0.2525 1
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0079 0.0395 0.0541
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Entamoeba histolytica calpain large subunit domain III containing protein 0.0087 0.0464 0.1705
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0243 0.0229
Brugia malayi Cathepsin L-like precursor 0.0342 0.2525 0.2511
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0061 0.0251 0.033
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0084 0.0435 0.042
Onchocerca volvulus 0.0141 0.0895 0.3497
Loa Loa (eye worm) hypothetical protein 0.0046 0.0127 0.0114
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0074 0.0357 0.0445
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0046 0.0127 0.0112
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Giardia lamblia Cathepsin B precursor 0.0276 0.1988 0.5645
Schistosoma mansoni hypothetical protein 0.0241 0.1706 0.1693
Giardia lamblia Cathepsin L precursor 0.0081 0.0412 0.1042
Trypanosoma brucei rac serine-threonine kinase, putative 0.0038 0.0059 0.0047
Plasmodium falciparum calpain 0.0261 0.1869 0.7345
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.1875 0.3028
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma brucei Calpain-like protein 2 0.0653 0.505 0.736
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma brucei Domain of unknown function (DUF1935), putative 0.0281 0.2032 0.2938
Trypanosoma cruzi cysteine peptidase, putative 0.0191 0.1306 0.1874
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0046 0.0127 0.0294
Trypanosoma cruzi cysteine peptidase inhibitor 0.0245 0.1742 0.2514
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Giardia lamblia DUB-1 0.0046 0.0127 0.0212
Trypanosoma brucei calpain, putative 0.0241 0.1706 0.2461
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0118 0.0712 0.0698
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0163 0.108 0.1508
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0229 0.0214
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.049 0.3726 0.5419
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0051 0.0166 0.0211
Brugia malayi p70 ribosomal S6 kinase beta 0.0035 0.004 0.0021
Brugia malayi cathepsin F-like cysteine proteinase 0.0081 0.0412 0.0394
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0565 0.4335 0.4326
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0243 0.1728 0.2493
Trypanosoma cruzi diphthine synthase, putative 0.0037 0.0055 0.0041
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0607 0.4677 0.6801
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0069 0.031 0.0428
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0262 0.1875 0.3028
Brugia malayi fibroinase precursor 0.0081 0.0412 0.0394
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0068 0.0302 0.1055
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0831 0.6486 0.9461
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase BAP1 0.0065 0.0278 0.0353
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0104 0.0594 0.058
Trichomonas vaginalis calpain, putative 0.0241 0.1706 0.2748
Trichomonas vaginalis Clan CD, family C13, legumain-like cysteine peptidase 0.0064 0.0273 0.0366
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0412 0.0596
Brugia malayi Peptidase family C54 containing protein 0.0086 0.0452 0.0434
Leishmania major trypanothione synthetase-like protein 0.0071 0.0327 0.0401
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0069 0.031 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Trypanosoma cruzi trypanothione synthetase 0.0071 0.0327 0.044
Entamoeba histolytica cysteine proteinase, putative 0.0232 0.1631 0.6402
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Loa Loa (eye worm) hypothetical protein 0.0074 0.0357 0.0344
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0081 0.0412 0.1414
Brugia malayi ubiquitin C-terminal hydrolase UCH-L5 0.0118 0.0712 0.0695
Giardia lamblia Hypothetical protein 0.0081 0.0412 0.1042
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0074 0.0357 0.0357
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Loa Loa (eye worm) PAN domain-containing protein 0.0045 0.0119 0.0105
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0081 0.0412 0.0397
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0779 0.6068 0.6068
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0046 0.0127 0.0127
Schistosoma mansoni peptidase 0.0046 0.0129 0.0114
Toxoplasma gondii PAN domain-containing protein 0.0045 0.0119 0.0319
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Toxoplasma gondii hypothetical protein 0.0241 0.1706 0.6703
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Toxoplasma gondii subtilisin SUB1 0.0058 0.0223 0.0737
Brugia malayi diphthine synthase 0.0037 0.0055 0.0036
Leishmania major inhibitor of cysteine peptidase 0.0245 0.1742 0.2482
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0565 0.4335 0.4326
Echinococcus granulosus membrane bound transcription factor site 1 0.0058 0.0223 0.0223
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0046 0.0127 0.0351
Trichomonas vaginalis ubiquitin specific protease, putative 0.0046 0.0127 0.0123
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0064 0.027 0.0318
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0046 0.0127 0.0212
Giardia lamblia Cathepsin L-like protease 0.0081 0.0412 0.1042
Plasmodium vivax unspecified product 0.0191 0.1306 0.4958
Giardia lamblia Cathepsin B precursor 0.0081 0.0412 0.1042
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0229 0.0214
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi small myristoylated protein 1-2 0.0438 0.3302 0.4799
Plasmodium vivax serine-repeat antigen (SERA) 0.0081 0.0412 0.1414
Trypanosoma cruzi Cysteine peptidase, Clan CF, family C15 0.0451 0.3408 0.4954
Entamoeba histolytica hypothetical protein 0.0081 0.0412 0.1495
Loa Loa (eye worm) hypothetical protein 0.0045 0.0119 0.0105
Toxoplasma gondii subtilisin SUB5 0.0058 0.0223 0.0737
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0074 0.0357 0.0484
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase isozyme 0.0131 0.0814 0.0814
Loa Loa (eye worm) hypothetical protein 0.0046 0.0127 0.0114
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0602 0.4635 0.6738
Trypanosoma cruzi major cysteine proteinase, putative 0.0081 0.0412 0.0564
Brugia malayi PAN domain containing protein 0.0045 0.0119 0.0101
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0051 0.0166 0.0189
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Plasmodium falciparum ubiquitin specific protease, putative 0.0046 0.0127 0.0294
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0081 0.0412 0.0397
Loa Loa (eye worm) hypothetical protein 0.0046 0.0127 0.0114
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0779 0.6068 1
Loa Loa (eye worm) TK/ROR protein kinase 0.0141 0.0895 0.0883
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0081 0.0411 0.0522
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0076 0.0372 0.0473
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Giardia lamblia Cathepsin B precursor 0.0081 0.0412 0.1042
Echinococcus multilocularis cathepsin L 0.0081 0.0412 0.0522
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0076 0.0372 0.0468
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0082 0.0416 0.0528
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0055 0.0202 0.0202
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0051 0.0166 0.0211
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0412 0.0596
Entamoeba histolytica cysteine protease, putative 0.0191 0.1306 0.5093
Plasmodium falciparum serine repeat antigen 4 0.0081 0.0412 0.1445
Trypanosoma brucei serine peptidase, clan SB, family S8-like protein 0.0062 0.0256 0.0337
Loa Loa (eye worm) papain family cysteine protease containing protein 0.011 0.0649 0.0636
Loa Loa (eye worm) hypothetical protein 0.0045 0.0119 0.0105
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0068 0.0302 0.1002
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0046 0.0127 0.0114
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0059 0.0229 0.0291
Brugia malayi GPI-anchor transamidase 0.0064 0.0273 0.0255
Loa Loa (eye worm) hypothetical protein 0.0059 0.0235 0.0222
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0515 0.3926 0.5695
Trypanosoma brucei hypothetical protein 0.0515 0.3926 0.5713
Echinococcus granulosus Furin 1 0.0319 0.2343 0.2343
Schistosoma mansoni ubiquitinyl hydrolase-UCH37 (C12 family) 0.0118 0.0712 0.0698
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0241 0.1706 0.2748
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0051 0.0166 0.0152
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0058 0.0223 0.0205
Leishmania major hypothetical protein, conserved 0.0141 0.0895 0.1237
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0076 0.0372 0.0372
Loa Loa (eye worm) endoprotease bli-4 0.1264 1 1
Brugia malayi Sex muscle abnormal protein 5 0.0272 0.196 0.1945
Loa Loa (eye worm) hypothetical protein 0.0241 0.1706 0.1694
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0084 0.0435 0.1588
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.049 0.3726 0.5419
Echinococcus multilocularis calpain 5 0.0328 0.2415 0.3065
Trichomonas vaginalis calpain, putative 0.0241 0.1706 0.2748
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0046 0.0127 0.0123
Trypanosoma cruzi cysteine peptidase, Clan CA, family C51, putative 0.0327 0.2408 0.3489
Loa Loa (eye worm) cysteine protease 0.0342 0.2525 0.2515
Schistosoma mansoni cercarial elastase (S01 family) 0.0059 0.0229 0.0214
Leishmania major cathepsin L-like protease 0.0342 0.2525 0.3635
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi pyroglutamyl-peptidase I, putative 0.0451 0.3408 0.4954
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0412 0.0596
Giardia lamblia High cysteine membrane protein Group 2 0.046 0.348 1
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0086 0.0452 0.0623
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0243 0.1728 0.2493
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Brugia malayi PAN domain containing protein 0.0045 0.0119 0.0101
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0076 0.0372 0.0507
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0191 0.1306 0.1293
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0182 0.1232 0.1218
Trypanosoma brucei CHAP domain containing protein, putative 0.0071 0.0327 0.044
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0696 0.5393 0.7862
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0082 0.0416 0.0604
Trypanosoma brucei glutathionylspermidine synthetase, putative 0.0071 0.0327 0.044
Onchocerca volvulus 0.0342 0.2525 1
Loa Loa (eye worm) hypothetical protein 0.0337 0.2483 0.2473
Toxoplasma gondii cathepsin CPL 0.0342 0.2525 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0081 0.0412 0.0596
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma brucei Small kinetoplastid calpain-related protein 1-5 0.0281 0.2032 0.2938
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0438 0.3306 0.4805
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0274 0.1975 0.2855
Trypanosoma brucei Calpain-like protein 1.1 0.0876 0.6852 1
Plasmodium vivax vivapain-3 0.0191 0.1306 0.4958
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0055 0.0202 0.0188
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Brugia malayi ubiquitin specific protease 14 0.0074 0.0357 0.0339
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0381 0.284 0.4122
Trichomonas vaginalis conserved hypothetical protein 0.035 0.2593 0.4222
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Toxoplasma gondii hypothetical protein 0.0045 0.0119 0.0319
Plasmodium falciparum serine repeat antigen 1 0.0081 0.0412 0.1445
Trypanosoma cruzi cysteine peptidase, putative 0.049 0.3726 0.5419
Loa Loa (eye worm) hypothetical protein 0.0152 0.0983 0.0971
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trichomonas vaginalis AGC family protein kinase 0.0038 0.0059 0.001
Echinococcus multilocularis musashi 0.0033 0.0019 0.0024
Echinococcus granulosus cathepsin L cysteine protease 0.0191 0.1306 0.1306
Loa Loa (eye worm) hypothetical protein 0.0232 0.1631 0.162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.049 0.3726 0.5419
Echinococcus granulosus enteropeptidase 0.0059 0.0229 0.0229
Toxoplasma gondii subtilisin SUB10 0.0058 0.0223 0.0737
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0068 0.0302 0.1055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Leishmania major small myristoylated protein-2 0.0744 0.5786 0.8432
Schistosoma mansoni hypothetical protein 0.0059 0.0229 0.0214
Brugia malayi Papain family cysteine protease containing protein 0.0081 0.0412 0.0394
Trypanosoma brucei amidase, putative 0.0071 0.0327 0.044
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0046 0.0127 0.0109
Toxoplasma gondii subtilisin SUB8 0.0058 0.0223 0.0737
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0074 0.0357 0.0505
Trypanosoma brucei cysteine peptidase, putative 0.0607 0.4677 0.6814
Leishmania major D-alanyl-glycyl endopeptidase-like protein,cysteine peptidase, Clan CA, family C51, putative 0.0327 0.2408 0.3462
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0342 0.2525 0.411
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Schistosoma mansoni otubain-1 (C65 family) 0.009 0.0484 0.047
Loa Loa (eye worm) hypothetical protein 0.0059 0.0229 0.0216
Plasmodium vivax subtilisin-like protease 1 0.0058 0.0223 0.0668
Loa Loa (eye worm) calpain 0.0361 0.2684 0.2674
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0515 0.3926 0.5713
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0271 0.1954 0.2794
Echinococcus multilocularis lamin dm0 0.0033 0.0019 0.0024
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0526 0.4015 0.5844
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0061 0.0247 0.078
Leishmania major cathepsin L-like protease 0.049 0.3726 0.54
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0243 0.1728 0.2461
Loa Loa (eye worm) hypothetical protein 0.0046 0.0127 0.0114
Schistosoma mansoni cathepsin S (C01 family) 0.0081 0.0412 0.0397
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0046 0.0127 0.0127
Mycobacterium ulcerans hypothetical protein 0.0059 0.0229 0.0163
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0205 0.1416 0.2003
Echinococcus granulosus cathepsin l1 0.0232 0.1631 0.1631
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0438 0.3306 0.4805
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0084 0.0435 0.0559
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Echinococcus granulosus protein will die slowly 0.0072 0.0338 0.0338
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0046 0.0127 0.0123
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0046 0.0127 0.0288
Echinococcus granulosus cysteine protease 0.0191 0.1306 0.1306
Loa Loa (eye worm) hypothetical protein 0.011 0.0649 0.0636
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0243 0.0224
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0058 0.0223 0.0283
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0046 0.0127 0.0351
Brugia malayi cathepsin B-like cysteine proteinase 0.0565 0.4335 0.4324
Entamoeba histolytica peptidase, C54 family 0.0048 0.0146 0.0426
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0061 0.0247 0.0323
Onchocerca volvulus 0.0059 0.0229 0.084
Leishmania major hypothetical protein, conserved 0.0281 0.2032 0.2909
Echinococcus multilocularis tissue type plasminogen activator 0.0141 0.0895 0.1136
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.049 0.3726 0.5419
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0342 0.2525 0.2515
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0081 0.0412 0.0596
Loa Loa (eye worm) hypothetical protein 0.0232 0.1631 0.162
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0138 0.0873 0.1363
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0342 0.2525 0.411
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.0127 0.0123
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.049 0.3726 0.5419

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 2.8184 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.0119 uM PubChem BioAssay. qHTS for Agonist of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 10 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 26.8545 uM PUBCHEM_BIOASSAY: qHTS profiling assay for firefly luciferase inhibitor/activator using purified enzyme and Km concentrations of substrates (counterscreen for miR-21 project). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2288, AID2289, AID2598, AID411] ChEMBL. No reference
Potency (functional) 29.081 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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