Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | coagulation factor II (thrombin) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.761 | 0.8437 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0039 | 0.0457 | 0.0457 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0039 | 0.0457 | 0.0506 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0039 | 0.0457 | 0.0457 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0197 | 0.9019 | 1 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0039 | 0.0457 | 0.0506 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.0039 | 0.0457 | 0.0506 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0057 | 0.1437 | 0.1594 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0039 | 0.0457 | 0.0506 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0039 | 0.0457 | 0.0506 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0039 | 0.0457 | 0.0506 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0184 | 0.8317 | 1 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.0039 | 0.0457 | 0.0506 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0039 | 0.0457 | 0.0506 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0039 | 0.0457 | 0.0506 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0039 | 0.0457 | 0.0457 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0457 | 0.0506 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel alpha 3 | 0.0039 | 0.0457 | 0.0506 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0057 | 0.1437 | 0.1437 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0057 | 0.1437 | 0.1594 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0057 | 0.1437 | 0.1594 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0039 | 0.0457 | 0.0457 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0031 | 0.0028 | 0.0028 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0039 | 0.0457 | 0.0457 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1437 | 0.1594 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0057 | 0.1437 | 0.1437 |
Loa Loa (eye worm) | cyclic-nucleotide gated cation channel | 0.0039 | 0.0457 | 0.0506 |
Brugia malayi | Cyclic-nucleotide gated cation channel | 0.0039 | 0.0457 | 0.0506 |
Echinococcus granulosus | voltage gated potassium channel | 0.0057 | 0.1437 | 0.1594 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0197 | 0.9019 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0057 | 0.1437 | 0.1594 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0184 | 0.8317 | 1 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0039 | 0.0457 | 0.0457 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0197 | 0.9019 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0197 | 0.9019 | 1 |
Echinococcus multilocularis | cyclic nucleotide gated cation channel | 0.0039 | 0.0457 | 0.0506 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0039 | 0.0457 | 0.0506 |
Schistosoma mansoni | 60S ribosomal protein L21 | 0.0031 | 0.0028 | 0.0028 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.